David S. Latchman, Ph.D. - Publications

Affiliations: 
Molecular Pathology University College London, London, United Kingdom 
Area:
Gene Regulation

205 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Artim-Esen B, Pericleous C, Mackie I, Ripoll VM, Latchman D, Isenberg D, Rahman A, Ioannou Y, Giles I. Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays. Arthritis Research & Therapy. 17: 47. PMID 25890027 DOI: 10.1186/s13075-015-0568-7  0.68
2015 Pericleous C, Ruiz-Limón P, Romay-Penabad Z, Marín AC, Garza-Garcia A, Murfitt L, Driscoll PC, Latchman DS, Isenberg DA, Giles I, Ioannou Y, Rahman A, Pierangeli SS. Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis. Rheumatology (Oxford, England). 54: 722-7. PMID 25273993 DOI: 10.1093/rheumatology/keu360  0.68
2015 Stephanou A, Scarabelli TM, Knight RA, Latchman DS. Antiapoptotic activity of the free caspase recruitment domain of procaspase-9: A Novel endogenous rescue pathway in cell death Journal of Biological Chemistry. 290: 1454. DOI: 10.1074/jbc.A114.108530  0.68
2014 Ripoll VM, Lambrianides A, Pierangeli SS, Poulton K, Ioannou Y, Heywood WE, Mills K, Latchman DS, Isenberg DA, Rahman A, Giles IP. Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. Blood. 124: 3808-16. PMID 25301710 DOI: 10.1182/blood-2014-05-577569  0.68
2014 Croca S, Bassett P, Pericleous C, Alber KF, Latchman D, Isenberg D, Giles I, Rahman A, Ioannou Y. Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study. Arthritis Research & Therapy. 16: R48. PMID 24502558 DOI: 10.1186/ar4477  0.68
2013 Carroll CJ, Sayan BS, Bailey SG, McCormick J, Stephanou A, Latchman DS, Townsend PA. Regulation of myocardial interleukin-6 expression by p53 and STAT1. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 542-8. PMID 23675777 DOI: 10.1089/jir.2012.0165  0.68
2013 Pericleous C, Clarke LA, Brogan PA, Latchman DS, Isenberg DA, Ioannou Y, Giles IP, Rahman A. Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome Thrombosis and Haemostasis. 109: 72-78. PMID 23152159 DOI: 10.1160/TH12-05-0346  0.68
2013 Barry SP, Ounzain S, McCormick J, Scarabelli TM, Chen-Scarabelli C, Saravolatz LII, Faggian G, Mazzucco A, Suzuki H, Thiemermann C, Knight RA, Latchman DS, Stephanou A. Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury International Journal of Cardiology. 163: 326-334. PMID 22030025 DOI: 10.1016/j.ijcard.2011.08.849  0.68
2012 McCormick J, Knight RA, Barry SP, Scarabelli TM, Abounit K, Latchman DS, Stephanou A. Autophagy in the stress-induced myocardium. Frontiers in Bioscience (Elite Edition). 4: 2131-2141. PMID 22202025  0.68
2012 Mccormick J, Suleman N, Scarabelli TM, Knight RA, Latchman DS, Stephanou A. STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy Journal of Cellular and Molecular Medicine. 16: 386-393. PMID 21447043 DOI: 10.1111/j.1582-4934.2011.01323.x  0.68
2011 Pericleous C, Miles J, Esposito D, Garza-Garcia A, Driscoll PC, Lambrianides A, Latchman D, Isenberg D, Rahman A, Ioannou Y, Giles I. Evaluating the conformation of recombinant domain I of β(2)-glycoprotein I and its interaction with human monoclonal antibodies. Molecular Immunology. 49: 56-63. PMID 21899894 DOI: 10.1016/j.molimm.2011.07.024  0.68
2011 Lambrianides A, Turner-Stokes T, Pericleous C, Ehsanullah J, Papadimitraki E, Poulton K, Ioannou Y, Lawrie A, Mackie I, Chen P, Latchman D, Isenberg D, Rahman A, Giles I. Interactions of human monoclonal and polyclonal antiphospholipid antibodies with serine proteases involved in hemostasis. Arthritis and Rheumatism. 63: 3512-21. PMID 21739425 DOI: 10.1002/art.30525  0.68
2011 Ulgen BO, Field MG, Qureshi W, Knight RA, Stephanou A, Latchman DS, Vasquez D, Barry SP, Saravolatz L, Scarabelli GM, Faggian G, Mazzucco A, Carol-Chen-Scarabelli, Scarabelli TM. The role of minocycline in ischemia-reperfusion injury: A comprehensive review of an old drug with new implications Recent Patents On Cardiovascular Drug Discovery. 6: 123-132. PMID 21599619 DOI: 10.2174/157489011795933783  0.68
2011 Ng KE, Joly P, Jayasinghe SN, Vernay B, Knight R, Barry SP, McComick J, Latchman D, Stephanou A. Bio-electrospraying primary cardiac cells: In vitro tissue creation and functional study Biotechnology Journal. 6: 86-95. PMID 21053334 DOI: 10.1002/biot.201000125  0.68
2011 Carroll CJ, Suleman N, Davidson SM, Faulkes DJ, Diss JK, Knight R, Stephanou A, Latchman DS, Townsend PA. Transgenic overexpression of HSP56 does not result in cardiac hypertrophy nor protect from ischaemia/reperfusion injury International Journal of Biochemistry and Cell Biology. 43: 74-79. PMID 20932935 DOI: 10.1016/j.biocel.2010.09.020  0.68
2011 Stephanou A, Latchman DS. Transcriptional modulation of heat-shock protein gene expression Biochemistry Research International. DOI: 10.1155/2011/238601  0.68
2010 Dimco G, Knight RA, Latchman DS, Stephanou A. STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest Cell Cycle. 9: 4638-4649. PMID 21084836 DOI: 10.4161/cc.9.23.13955  0.68
2010 Barry SP, Townsend PA, Knight RA, Scarabelli TM, Latchman DS, Stephanou A. STAT3 modulates the DNA damage response pathway International Journal of Experimental Pathology. 91: 506-514. PMID 20804538 DOI: 10.1111/j.1365-2613.2010.00734.x  0.68
2010 Calissano M, Latchman DS. Cell-specific regulation of the pro-survival Brn-3b transcription factor by microRNAs Molecular and Cellular Neuroscience. 45: 317-323. PMID 20609388 DOI: 10.1016/j.mcn.2010.06.015  0.68
2010 Barry SP, Lawrence KM, McCormick J, Soond SM, Hubank M, Eaton S, Sivarajah A, Scarabelli TM, Knight RA, Thiemermann C, Latchman DS, Townsend PA, Stephanou A. New targets of urocortin-mediated cardioprotection Journal of Molecular Endocrinology. 45: 69-85. PMID 20501665 DOI: 10.1677/JME-09-0148  0.68
2010 Lambrianides A, Carroll CJ, Pierangeli SS, Pericleous C, Branch W, Rice J, Latchman DS, Townsend P, Isenberg DA, Rahman A, Giles IP. Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways Journal of Immunology. 184: 6622-6628. PMID 20483743 DOI: 10.4049/jimmunol.0902765  0.68
2010 Fraser SP, Ozerlat-Gunduz I, Onkal R, Diss JK, Latchman DS, Djamgoz MB. Estrogen and non-genomic upregulation of voltage-gated Na(+) channel activity in MDA-MB-231 human breast cancer cells: role in adhesion. Journal of Cellular Physiology. 224: 527-39. PMID 20432453 DOI: 10.1002/jcp.22154  0.68
2010 Gascoyne DM, Dunne J, Behjati S, Sebire NJ, Anderson J, Latchman DS. EWS/ETS proteins promote expression and regulate function of the homeodomain transcription factor BRN3A Oncogene. 29: 3134-3145. PMID 20348952 DOI: 10.1038/onc.2010.72  0.68
2010 Berwick DC, Diss JKJ, Budhram-Mahadeo VS, Latchman DS. A simple technique for the prediction of interacting proteins reveals a direct Brn-3a-androgen receptor interaction Journal of Biological Chemistry. 285: 15286-15295. PMID 20228055 DOI: 10.1074/jbc.M109.071456  0.68
2010 Ndisang D, Khan A, Lorenzato F, Sindos M, Singer A, Latchman DS. The cellular transcription factor Brn-3a and the smoking-related substance nicotine interact to regulate the activity of the HPV URR in the cervix Oncogene. 29: 2701-2711. PMID 20190800 DOI: 10.1038/onc.2010.33  0.68
2010 Ripley BJM, Fujimoto M, Serada S, Ohkawara T, Nishikawa T, Terabe F, Matsukawa Y, Stephanou A, Knight RA, Isenberg DA, Latchman DS, Kishimoto T, Naka T. Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression International Immunology. 22: 359-366. PMID 20190037 DOI: 10.1093/intimm/dxq015  0.68
2010 O'Neill SG, Giles I, Lambrianides A, Manson J, D'Cruz D, Schrieber L, March LM, Latchman DS, Isenberg DA, Rahman A. Antibodies to apolipoprotein A-I, high-density lipoprotein, and C-reactive protein are associated with disease activity in patients with systemic lupus erythematosus Arthritis and Rheumatism. 62: 845-854. PMID 20131231 DOI: 10.1002/art.27286  0.68
2010 van der Weerd L, Tariq Akbar M, Aron Badin R, Valentim LM, Thomas DL, Wells DJ, Latchman DS, Gadian DG, Lythgoe MF, de Belleroche JS. Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 849-56. PMID 19997117 DOI: 10.1038/jcbfm.2009.249  0.68
2009 Francis YI, Fà M, Ashraf H, Zhang H, Staniszewski A, Latchman DS, Arancio O. Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 18: 131-9. PMID 19625751 DOI: 10.3233/JAD-2009-1134  0.68
2009 Barry SP, Townsend PA, McCormick J, Knight RA, Scarabelli TM, Latchman DS, Stephanou A. STAT3 deletion sensitizes cells to oxidative stress Biochemical and Biophysical Research Communications. 385: 324-329. PMID 19450559 DOI: 10.1016/j.bbrc.2009.05.051  0.68
2009 Sleiman PM, Healy DG, Muqit MM, Yang YX, Van Der Brug M, Holton JL, Revesz T, Quinn NP, Bhatia K, Diss JK, Lees AJ, Cookson MR, Latchman DS, Wood NW. Characterisation of a novel NR4A2 mutation in Parkinson's disease brain. Neuroscience Letters. 457: 75-9. PMID 19429166 DOI: 10.1016/j.neulet.2009.03.021  0.68
2009 Giles I, Pericleous C, Liu X, Ehsanullah J, Clarke L, Brogan P, Newton-West M, Swerlick R, Lambrianides A, Chen P, Latchman D, Isenberg D, Pierangeli S, Rahman A. Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions Journal of Immunology. 182: 4836-4843. PMID 19342662 DOI: 10.4049/jimmunol.0804241  0.68
2009 Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW, Duchen MR, Abramov AY. PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. Molecular Cell. 33: 627-38. PMID 19285945 DOI: 10.1016/j.molcel.2009.02.013  0.68
2009 Ioannou Y, Romay-Penabad Z, Pericleous C, Giles I, Papalardo E, Vargas G, Shilagard T, Latchman DS, Isenberg DA, Rahman A, Pierangeli S. In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of β2-glycoprotein I: Proof of concept Journal of Thrombosis and Haemostasis. 7: 833-842. PMID 19220729 DOI: 10.1111/j.1538-7836.2009.03316.x  0.68
2009 Yang YX, Wood NW, Latchman DS. Molecular basis of Parkinson's disease Neuroreport. 20: 150-156. PMID 19151598 DOI: 10.1097/WNR.0b013e32831c50df  0.68
2009 Berwick DC, Calissano M, Corness JD, Cook SJ, Latchman DS. Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation. Brain Research. 1256: 8-18. PMID 19135033 DOI: 10.1016/j.brainres.2008.12.009  0.68
2009 Scarabelli TM, Mariotto S, Abdel-Azeim S, Shoji K, Darra E, Stephanou A, Chen-Scarabelli C, Marechal JD, Knight R, Ciampa A, Saravolatz L, de Prati AC, Yuan Z, Cavalieri E, Menegazzi M, ... Latchman D, et al. Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion-induced injury Febs Letters. 583: 531-541. PMID 19116149 DOI: 10.1016/j.febslet.2008.12.037  0.68
2009 Badin RA, Modo M, Cheetham M, Thomas DL, Gadian DG, Latchman DS, Lythgoe MF. Protective effect of post-ischaemic viral delivery of heat shock proteins in vivo. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 254-63. PMID 18781161 DOI: 10.1038/jcbfm.2008.106  0.68
2008 Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Abramov AS, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, Downward J, Mansfield L, Jat P, Taylor J, ... ... Latchman D, et al. PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. Plos One. 3: e2455. PMID 18560593 DOI: 10.1371/journal.pone.0002455  0.68
2008 Scarabelli TM, Townsend PA, Chen Scarabelli C, Yuan Z, McCauley RB, Di Rezze J, Patel D, Putt J, Allebban Z, Abboud J, Chilukuri K, Gardin J, Saravolatz L, Knight RA, Latchman DS, et al. Amino acid supplementation differentially modulates STAT1 and STAT3 activation in the myocardium exposed to ischemia/reperfusion injury. The American Journal of Cardiology. 101: 63E-68E. PMID 18514629 DOI: 10.1016/j.amjcard.2008.03.003  0.68
2008 Yang YX, Latchman DS. Nurr1 transcriptionally regulates the expression of α-synuclein Neuroreport. 19: 867-871. PMID 18463503 DOI: 10.1097/WNR.0b013e3282ffda48  0.68
2008 Hudson CD, Sayan AE, Melino G, Knight RA, Latchman DS, Budhram-Mahadeo V. Brn-3a/POU4F1 interacts with and differentially affects p73-mediated transcription Cell Death and Differentiation. 15: 1266-1278. PMID 18421303 DOI: 10.1038/cdd.2008.45  0.68
2008 Soond SM, Barry SP, Melino G, Knight RA, Latchman DS, Stephanou A. p73-mediated transcriptional activity is negatively regulated by polo-like kinase Cell Cycle. 7: 1214-1223. PMID 18418051  0.68
2008 Soond SM, Townsend PA, Barry SP, Knight RA, Latchman DS, Stephanou A. ERK and the F-box protein βTRCP target STAT1 for degradation Journal of Biological Chemistry. 283: 16077-16083. PMID 18378670 DOI: 10.1074/jbc.M800384200  0.68
2008 Farooqui-Kabir SR, Diss JKJ, Henderson D, Marber MS, Latchman DS, Budhram-Mahadeo V, Heads RJ. Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression Cell Stress and Chaperones. 13: 297-312. PMID 18368538 DOI: 10.1007/s12192-008-0028-2  0.68
2008 Knight RA, Chen-Scarabelli C, Yuan Z, McCauley RB, Di Rezze J, Scarabelli GM, Townsend PA, Latchman D, Saravolatz L, Faggian G, Mazzucco A, Chowdrey HS, Stephanou A, Scarabelli TM. Cardiac release of urocortin precedes the occurrence of irreversible myocardial damage in the rat heart exposed to ischemia/reperfusion injury. Febs Letters. 582: 984-90. PMID 18295601 DOI: 10.1016/j.febslet.2008.02.035  0.68
2008 Barry SP, Jayasinghe SN, Pericleous C, Hubank M, Latchman DS, Stephanou A. Gene expression studies on bio-electrosprayed primary cardiac myocytes Biotechnology Journal. 3: 530-535. PMID 18293311 DOI: 10.1002/biot.200700266  0.68
2008 Sharp PS, Akbar MT, Bouri S, Senda A, Joshi K, Chen HJ, Latchman DS, Wells DJ, de Belleroche J. Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression Neurobiology of Disease. 30: 42-55. PMID 18255302 DOI: 10.1016/j.nbd.2007.12.002  0.68
2008 Diss JK, Calissano M, Gascoyne D, Djamgoz MB, Latchman DS. Identification and characterization of the promoter region of the Nav1.7 voltage-gated sodium channel gene (SCN9A). Molecular and Cellular Neurosciences. 37: 537-47. PMID 18249135 DOI: 10.1016/j.mcn.2007.12.002  0.68
2008 Diss JK, Fraser SP, Walker MM, Patel A, Latchman DS, Djamgoz MB. Beta-subunits of voltage-gated sodium channels in human prostate cancer: quantitative in vitro and in vivo analyses of mRNA expression. Prostate Cancer and Prostatic Diseases. 11: 325-33. PMID 17893701 DOI: 10.1038/sj.pcan.4501012  0.68
2008 Budhram-Mahadeo VS, Irshad S, Bowen S, Lee SA, Samady L, Tonini GP, Latchman DS. Proliferation-associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cells Oncogene. 27: 145-154. PMID 17637757 DOI: 10.1038/sj.onc.1210621  0.68
2007 Wagstaff MJ, Shah M, McGrouther DA, Latchman DS. The heat shock proteins and plastic surgery. Journal of Plastic, Reconstructive & Aesthetic Surgery : Jpras. 60: 974-82. PMID 17662462 DOI: 10.1016/j.bjps.2006.03.065  0.68
2007 Lambrianides A, Giles I, Ioannou Y, Mason L, Latchman DS, Manson JJ, Isenberg DA, Rahman A. Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome Arthritis and Rheumatism. 56: 2392-2401. PMID 17599767 DOI: 10.1002/art.22743  0.68
2007 Calissano M, Diss JKJ, Latchman DS. Post-transcriptional regulation of the Brn-3b transcription factor in differentiating neuroblastoma cells Febs Letters. 581: 2490-2496. PMID 17490655 DOI: 10.1016/j.febslet.2007.04.066  0.68
2007 Townsend PA, Davidson SM, Clarke SJ, Khaliulin I, Carroll CJ, Scarabelli TM, Knight RA, Stephanou A, Latchman DS, Halestrap AP. Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress American Journal of Physiology - Heart and Circulatory Physiology. 293: H928-H938. PMID 17483234 DOI: 10.1152/ajpheart.01135.2006  0.68
2007 Zourlidou A, Gidalevitz T, Kristiansen M, Landles C, Woodman B, Wells DJ, Latchman DS, de Belleroche J, Tabrizi SJ, Morimoto RI, Bates GP. Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation. Human Molecular Genetics. 16: 1078-90. PMID 17360721 DOI: 10.1093/hmg/ddm057  0.68
2007 Soond SM, Carroll C, Townsend PA, Sayan E, Melino G, Behrmann I, Knight RA, Latchman DS, Stephanou A. STAT1 regulates p73-mediated Bax gene expression Febs Letters. 581: 1217-1226. PMID 17346710 DOI: 10.1016/j.febslet.2007.02.049  0.68
2007 Francis YI, Diss JKJ, Kariti M, Stephanou A, Latchman DS. p300 activation by Presenilin 1 but not by its M146L mutant Neuroscience Letters. 413: 137-140. PMID 17197080 DOI: 10.1016/j.neulet.2006.11.036  0.68
2007 Ioannou Y, Pericleous C, Giles I, Latchman DS, Isenberg DA, Rahman A. Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human β2-glycoprotein I: Mutation studies including residues R39 to R43 Arthritis and Rheumatism. 56: 280-290. PMID 17195232 DOI: 10.1002/art.22306  0.68
2007 Barry SP, Townsend PA, Latchman DS, Stephanou A. Role of the JAK-STAT pathway in myocardial injury Trends in Molecular Medicine. 13: 82-89. PMID 17194625 DOI: 10.1016/j.molmed.2006.12.002  0.68
2007 Latchman DS. Eukaryotic Transcription Factors Eukaryotic Transcription Factors 0.68
2006 Budhram-Mahadeo VS, Bowen S, Lee S, Perez-Sanchez C, Ensor E, Morris PJ, Latchman DS. Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression Nucleic Acids Research. 34: 6640-6652. PMID 17145718 DOI: 10.1093/nar/gkl878  0.68
2006 Lawrence KM, Latchman DS. The Urocortins: Mechanisms of cardioprotection and therapeutic potential Mini-Reviews in Medicinal Chemistry. 6: 1119-1126. PMID 17073712 DOI: 10.2174/138955706778560111  0.68
2006 Yang YX, Muqit MMK, Latchman DS. Induction of parkin expression in the presence of oxidative stress European Journal of Neuroscience. 24: 1366-1372. PMID 16987221 DOI: 10.1111/j.1460-9568.2006.04998.x  0.68
2006 Abou-Sleiman PM, Muqit MMK, McDonald NQ, Yang YX, Gandhi S, Healy DG, Harvey K, Harvey RJ, Deas E, Bhatia K, Quinn N, Lees A, Latchman DS, Wood NW. A heterozygous effect for PINK1 mutations in Parkinson's disease Annals of Neurology. 60: 414-419. PMID 16969854 DOI: 10.1002/ana.20960  0.68
2006 Giles I, Lambrianides N, Pattni N, Faulkes D, Latchman D, Chen P, Pierangeli S, Isenberg D, Rahman A. Arginine residues are important in determining the binding of human monoclonal antiphospholipid antibodies to clinically relevant antigens Journal of Immunology. 177: 1729-1736. PMID 16849482  0.68
2006 Soond SM, Latchman DS, Stephanou A. STAT signalling in the heart and cardioprotection Expert Reviews in Molecular Medicine. 8: 1-16. PMID 16836797 DOI: 10.1017/S1462399406000032  0.68
2006 Muqit MM, Abou-Sleiman PM, Saurin AT, Harvey K, Gandhi S, Deas E, Eaton S, Payne Smith MD, Venner K, Matilla A, Healy DG, Gilks WP, Lees AJ, Holton J, Revesz T, ... ... Latchman DS, et al. Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress. Journal of Neurochemistry. 98: 156-69. PMID 16805805 DOI: 10.1111/j.1471-4159.2006.03845.x  0.68
2006 Francis YI, Stephanou A, Latchman DS. CREB-binding protein activation by presenilin 1 but not by its M146L mutant Neuroreport. 17: 917-921. PMID 16738488 DOI: 10.1097/01.wnr.0000220137.06542.a0  0.68
2006 Gandhi S, Muqit MM, Stanyer L, Healy DG, Abou-Sleiman PM, Hargreaves I, Heales S, Ganguly M, Parsons L, Lees AJ, Latchman DS, Holton JL, Wood NW, Revesz T. PINK1 protein in normal human brain and Parkinson's disease. Brain : a Journal of Neurology. 129: 1720-31. PMID 16702191 DOI: 10.1093/brain/awl114  0.68
2006 Valentim L, Laurence KM, Townsend PA, Carroll CJ, Soond S, Scarabelli TM, Knight RA, Latchman DS, Stephanou A. Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury Journal of Molecular and Cellular Cardiology. 40: 846-852. PMID 16697404 DOI: 10.1016/j.yjmcc.2006.03.428  0.68
2006 Kabakov AE, Malyutina YV, Latchman DS. Hsf1-mediated stress response can transiently enhance cellular radioresistance Radiation Research. 165: 410-423. PMID 16579653 DOI: 10.1667/RR3514.1  0.68
2006 Scarabelli TM, Knight R, Stephanou A, Townsend P, Chen-Scarabelli C, Lawrence K, Gottlieb R, Latchman D, Narula J. Clinical implications of apoptosis in ischemic myocardium Current Problems in Cardiology. 31: 181-264. PMID 16503249 DOI: 10.1016/j.cpcardiol.2005.11.002  0.68
2006 Ioannou Y, Giles I, Lambrianides A, Richardson C, Pearl LH, Latchman DS, Isenberg DA, Rahman A. A novel expression system of domain I of human beta2 glycoprotein I in Escherichia coli Bmc Biotechnology. 6. PMID 16472380 DOI: 10.1186/1472-6750-6-8  0.68
2006 Budhram-Mahadeo VS, Latchman DS. Targeting Brn-3b in breast cancer therapy Expert Opinion On Therapeutic Targets. 10: 15-25. PMID 16441225 DOI: 10.1517/14728222.10.1.15  0.68
2006 Diss JK, Faulkes DJ, Walker MM, Patel A, Foster CS, Budhram-Mahadeo V, Djamgoz MB, Latchman DS. Brn-3a neuronal transcription factor functional expression in human prostate cancer. Prostate Cancer and Prostatic Diseases. 9: 83-91. PMID 16276351 DOI: 10.1038/sj.pcan.4500837  0.68
2006 Ndisang D, Faulkes DJ, Gascoyne D, Lee SA, Ripley BJ, Sindos M, Singer A, Budhram-Mahadeo V, Cason J, Latchman DS. Differential regulation of different human papilloma virus variants by the POU family transcription factor Brn-3a. Oncogene. 25: 51-60. PMID 16247485 DOI: 10.1038/sj.onc.1209006  0.68
2006 Smart N, Mojet MH, Latchman DS, Marber MS, Duchen MR, Heads RJ. IL-6 induces PI 3-kinase and nitric oxide-dependent protection and preserves mitochondrial function in cardiomyocytes Cardiovascular Research. 69: 164-177. PMID 16219301 DOI: 10.1016/j.cardiores.2005.08.017  0.68
2006 Samady L, Faulkes DJ, Budhram-Mahadeo V, Ndisang D, Potter E, Brabant G, Latchman DS. The Brn-3b POU family transcription factor represses plakoglobin gene expression in human breast cancer cells International Journal of Cancer. 118: 869-878. PMID 16152597 DOI: 10.1002/ijc.21435  0.68
2006 Ndisang D, Lorenzato F, Sindos M, Singer A, Latchman DS. Detection of cervical abnormalities in a developing country using measurement of Brn-3a in cervical smears Gynecologic Oncology. 100: 89-94. PMID 16126264 DOI: 10.1016/j.ygyno.2005.07.109  0.68
2006 Badin RA, Lythgoe MF, van der Weerd L, Thomas DL, Gadian DG, Latchman DS. Neuroprotective effects of virally delivered HSPs in experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 371-81. PMID 16079790 DOI: 10.1038/sj.jcbfm.9600190  0.68
2006 McCormick J, Barry SP, Sivarajah A, Stefanutti G, Townsend PA, Lawrence KM, Eaton S, Knight RA, Thiemermann C, Latchman DS, Stephanou A. Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury Faseb Journal. 20: E1404-E1410. DOI: 10.1096/fj.06-6188fje  0.68
2005 Latchman DS. Herpes simplex virus-based vectors for the treatment of cancer and neurodegenerative disease Current Opinion in Molecular Therapeutics. 7: 415-418. PMID 16248276  0.68
2005 Stephanou A, Latchman DS. Opposing actions of STAT-1 and STAT-3 Growth Factors. 23: 177-182. PMID 16243709 DOI: 10.1080/08977190500178745  0.68
2005 Mason LJ, Lambrianides A, Haley JD, Manson JJ, Latchman DS, Isenberg DA, Rahman A. Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity. Arthritis Research & Therapy. 7: R971-83. PMID 16207338 DOI: 10.1186/ar1768  0.68
2005 Fauchon MAC, Pell TJ, Baxter GF, Yellon DM, Latchman DS, Hubank MF, Mayne LV. Representational difference analysis of cDNA identifies novel genes expressed following preconditioning of the heart Experimental and Molecular Medicine. 37: 311-322. PMID 16155408  0.68
2005 Calissano M, Faulkes D, Latchman DS. Phosphorylation of the Brn-3a transcription factor is modulated during differentiation and regulates its functional activity Molecular Brain Research. 141: 10-18. PMID 16126301 DOI: 10.1016/j.molbrainres.2005.07.013  0.68
2005 Fraser SP, Diss JK, Chioni AM, Mycielska ME, Pan H, Yamaci RF, Pani F, Siwy Z, Krasowska M, Grzywna Z, Brackenbury WJ, Theodorou D, Koyutürk M, Kaya H, Battaloglu E, ... ... Latchman DS, et al. Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 5381-9. PMID 16061851 DOI: 10.1158/1078-0432.CCR-05-0327  0.68
2005 Chen-Scarabelli C, Hughes SE, Landon G, Rowley P, Allebban Z, Lawson N, Saravolatz L, Gardin J, Latchman D, Scarabelli TM. A case of fatal ephedra intake associated with lipofuscin accumulation, caspase activation and cleavage of myofibrillary proteins. European Journal of Heart Failure. 7: 927-30. PMID 16054866 DOI: 10.1016/j.ejheart.2004.09.012  0.68
2005 Latchman DS. Hsp27 and cell survival in neurones International Journal of Hyperthermia. 21: 393-402. PMID 16048837 DOI: 10.1080/02656730400023664  0.68
2005 Collino M, Patel NSA, Lawrence KM, Collin M, Latchman DS, Yaqoob MM, Thiemermann C. The selective PPARγ antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion Kidney International. 68: 529-536. PMID 16014029 DOI: 10.1111/j.1523-1755.2005.00430.x  0.68
2005 van der Weerd L, Lythgoe MF, Badin RA, Valentim LM, Akbar MT, de Belleroche JS, Latchman DS, Gadian DG. Neuroprotective effects of HSP70 overexpression after cerebral ischaemia--an MRI study. Experimental Neurology. 195: 257-66. PMID 15936758 DOI: 10.1016/j.expneurol.2005.05.002  0.68
2005 Ripley BJM, Goncalves B, Isenberg DA, Latchman DS, Rahman A. Raised levels of interleukin 6 in systemic lupus erythematosus correlate with anaemia Annals of the Rheumatic Diseases. 64: 849-853. PMID 15897306 DOI: 10.1136/ard.2004.022681  0.68
2005 Bandopadhyay R, Kingsbury AE, Muqit MM, Harvey K, Reid AR, Kilford L, Engelender S, Schlossmacher MG, Wood NW, Latchman DS, Harvey RJ, Lees AJ. Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition Neurobiology of Disease. 20: 401-411. PMID 15894486 DOI: 10.1016/j.nbd.2005.03.021  0.68
2005 Patel YJK, Payne Smith MD, De Belleroche J, Latchman DS. Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells Molecular Brain Research. 134: 256-274. PMID 15836922 DOI: 10.1016/j.molbrainres.2004.10.028  0.68
2005 Lee SA, Ndisang D, Patel C, Dennis JH, Faulkes DJ, D'Arrigo C, Samady L, Farooqui-Kabir S, Heads RJ, Latchman DS, Budhram-Mahadeo VS. Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in cancer and is required for maximal activation of the HSP-27 promoter Cancer Research. 65: 3072-3080. PMID 15833836  0.68
2005 Ripley BJM, Rahman MA, Isenberg DA, Latchman DS. Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies to Brn-3 and overexpression of Hsp90 Arthritis and Rheumatism. 52: 1171-1179. PMID 15818685 DOI: 10.1002/art.21000  0.68
2005 Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage Journal of Cell Science. 118: 1629-1639. PMID 15784679 DOI: 10.1242/jcs.01728  0.68
2005 Lawrence KM, Kabir AMN, Bellahcene M, Davidson S, Cao XB, McCormick J, Mesquita RA, Carroll CJ, Chanalaris A, Townsend PA, Hubank M, Stephanou A, Knight RA, Marber MS, Latchman DS. Cardioprotection mediated by urocortin is dependent on PKCε activation Faseb Journal. 19: 831-833. PMID 15764590 DOI: 10.1096/fj.04-2506fje  0.68
2005 Kumar S, Bunting KA, Kalsi J, Hinks JA, Latchman DS, Pearl LH, Isenberg DA. Lupus autoantibodies to native DNA preferentially bind DNA presented on PolIV Immunology. 114: 418-427. PMID 15720443 DOI: 10.1111/j.1365-2567.2005.02090.x  0.68
2005 Chanalaris A, Lawrence KM, Townsend PA, Davidson S, Jashmidi Y, Stephanou A, Knight RD, Hsu SY, Hsueh AJW, Latchman DS. Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway Biochemical and Biophysical Research Communications. 328: 442-448. PMID 15694367 DOI: 10.1016/j.bbrc.2005.01.001  0.68
2005 Hudson CD, Morris PJ, Latchman DS, Budhram-Mahadeo VS. Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate Journal of Biological Chemistry. 280: 11851-11858. PMID 15598651 DOI: 10.1074/jbc.M408679200  0.68
2005 Davidson SM, Townsend PA, Carroll C, Yurek-George A, Balasubramanyam K, Kundu TK, Stephanou A, Packham G, Ganesan A, Latchman DS. The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin Chembiochem. 6: 162-170. PMID 15593114 DOI: 10.1002/cbic.200400246  0.68
2005 Kumar S, Nagl S, Kalsi JK, Ravirajan CT, Athwal D, Latchman DS, Pearl LH, Isenberg DA. Beta-2-glycoprotein specificity of human anti-phospholipid antibody resides on the light chain: A novel mechanism for acquisition of cross-reactivity by an autoantibody Molecular Immunology. 42: 39-48. PMID 15488942 DOI: 10.1016/j.molimm.2004.07.012  0.68
2005 Townsend PA, Stephanou A, Packham G, Latchman DS. BAG-1: A multi-functional pro-survival molecule International Journal of Biochemistry and Cell Biology. 37: 251-259. PMID 15474970 DOI: 10.1016/j.biocel.2004.03.016  0.68
2005 Stephanou A, Latchman DS. Molecular chaperone-cytokine interactions at the transcriptional level Molecular Chaperones and Cell Signalling. 179-191. DOI: 10.1017/CBO9780511546310.012  0.68
2004 Latchman DS. Protective effect of heat shock proteins in the nervous system. Current Neurovascular Research. 1: 21-7. PMID 16181063  0.68
2004 Kabakov AE, Budagova KR, Malyutina YV, Latchman DS, Csermely P. Pharmacological attenuation of apoptosis in reoxygenated endothelial cells. Cellular and Molecular Life Sciences : Cmls. 61: 3076-86. PMID 15583868 DOI: 10.1007/s00018-004-4204-y  0.68
2004 Munarriz E, Barcaroli D, Stephanou A, Townsend PA, Maisse C, Terrinoni A, Neale MH, Martin SJ, Latchman DS, Knight RA, Melino G, De Laurenzi V. PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73. Molecular and Cellular Biology. 24: 10593-610. PMID 15572666 DOI: 10.1128/MCB.24.24.10593-10610.2004  0.68
2004 Hudson CD, Podesta J, Henderson D, Latchman DS, Budhram-Mahadeo V. Coexpression of Brn-3a POU protein with p53 in a population of neuronal progenitor cells is associated with differentiation and protection against apoptosis Journal of Neuroscience Research. 78: 803-814. PMID 15532030 DOI: 10.1002/jnr.20299  0.68
2004 MacCormac LP, Muqit MM, Faulkes DJ, Wood NW, Latchman DS. Reduction in endogenous parkin levels renders glial cells sensitive to both caspase-dependent and caspase-independent cell death. The European Journal of Neuroscience. 20: 2038-48. PMID 15450083 DOI: 10.1111/j.1460-9568.2004.03659.x  0.68
2004 Lawrence KM, Townsend PA, Davidson SM, Carroll CJ, Eaton S, Hubank M, Knight RA, Stephanou A, Latchman DS. The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage. Biochemical and Biophysical Research Communications. 321: 479-86. PMID 15358201 DOI: 10.1016/j.bbrc.2004.06.170  0.68
2004 Townsend PA, Scarabelli TM, Pasini E, Gitti G, Menegazzi M, Suzuki H, Knight RA, Latchman DS, Stephanou A. Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1621-3. PMID 15319365 DOI: 10.1096/fj.04-1716fje  0.68
2004 Farooqui-Kabir SR, Budhram-Mahadeo V, Lewis H, Latchman DS, Marber MS, Heads RJ. Regulation of Hsp27 expression and cell survival by the POU transcription factor Brn3a. Cell Death and Differentiation. 11: 1242-4. PMID 15272315 DOI: 10.1038/sj.cdd.4401478  0.68
2004 West DA, Valentim LM, Lythgoe MF, Stephanou A, Proctor E, van der Weerd L, Ordidge RJ, Latchman DS, Gadian DG. MR image-guided investigation of regional signal transducers and activators of transcription-1 activation in a rat model of focal cerebral ischemia. Neuroscience. 127: 333-9. PMID 15262323 DOI: 10.1016/j.neuroscience.2004.05.022  0.68
2004 Faulkes DJ, Ensor E, Le Rouzic E, Latchman DS. Distinct domains of Brn-3a regulate apoptosis and neurite outgrowth in vivo. Neuroreport. 15: 1421-5. PMID 15194866 DOI: 10.1097/01.wnr.0000129371.81377.05  0.68
2004 Kumar S, Kalsi J, Bunting K, Ravirajan CT, Latchman DS, Pearl LH, Isenberg DA. Fine binding characteristics of human autoantibodies-partial molecular characterization. Molecular Immunology. 41: 495-510. PMID 15183928 DOI: 10.1016/j.molimm.2004.03.039  0.68
2004 Thomas GR, Faulkes DJ, Gascoyne D, Latchman DS. EWS differentially activates transcription of the Brn-3a long and short isoform mRNAs from distinct promoters Biochemical and Biophysical Research Communications. 318: 1045-1051. PMID 15147979 DOI: 10.1016/j.bbrc.2004.04.134  0.68
2004 Parkinson EJ, Townsend PA, Stephanou A, Latchman DS, Eaton S, Pierro A. The Protective Effect of Moderate Hypothermia during Intestinal Ischemia-Reperfusion is Associated with Modification of Hepatic Transcription Factor Activation Journal of Pediatric Surgery. 39: 696-701. PMID 15137002 DOI: 10.1016/j.jpedsurg.2004.01.025  0.68
2004 Calissano M, Ensor E, Brown DR, Latchman DS. Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors. Neuroreport. 15: 483-6. PMID 15094508 DOI: 10.1097/00001756-200403010-00020  0.68
2004 Scarabelli TM, Pasini E, Stephanou A, Chen-Scarabelli C, Saravolatz L, Knight RA, Latchman DS, Gardin JM. Nutritional supplementation with mixed essential amino acids enhances myocyte survival, preserving mitochondrial functional capacity during ischemia-reperfusion injury. The American Journal of Cardiology. 93: 35A-40A. PMID 15094104 DOI: 10.1016/j.amjcard.2003.11.008  0.68
2004 Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, Ali Z, Del Turco D, Bentivoglio AR, Healy DG, Albanese A, Nussbaum R, González-Maldonado R, Deller T, Salvi S, ... ... Latchman DS, et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science (New York, N.Y.). 304: 1158-60. PMID 15087508 DOI: 10.1126/science.1096284  0.68
2004 Ravirajan CT, Wang Y, Matis LA, Papadaki L, Griffiths MH, Latchman DS, Isenberg DA. Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody Rheumatology. 43: 442-447. PMID 15024133 DOI: 10.1093/rheumatology/keh083  0.68
2004 Gascoyne DM, Thomas GR, Latchman DS. The effects of Brn-3a on neuronal differentiation and apoptosis are differentially modulated by EWS and its oncogenic derivative EWS/Fli-1. Oncogene. 23: 3830-40. PMID 15021903 DOI: 10.1038/sj.onc.1207497  0.68
2004 Alsbury S, Papageorgiou K, Latchman DS. Heat shock proteins can protect aged human and rodent cells from different stressful stimuli. Mechanisms of Ageing and Development. 125: 201-9. PMID 15013664 DOI: 10.1016/j.mad.2003.11.015  0.68
2004 Jamshidi Y, Zourlidou A, Carroll CJ, Sinclair J, Latchman DS. Signal-transduction pathways involved in the hypertrophic effect of hsp56 in neonatal cardiomyocytes Journal of Molecular and Cellular Cardiology. 36: 381-392. PMID 15010277 DOI: 10.1016/j.yjmcc.2003.12.011  0.68
2004 Zourlidou A, Payne Smith MD, Latchman DS. HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells. Journal of Neurochemistry. 88: 1439-48. PMID 15009645  0.68
2004 Gusterson RJ, Yuan LW, Latchman DS. Distinct serine residues in CBP and p300 are necessary for their activation by phenylephrine. The International Journal of Biochemistry & Cell Biology. 36: 893-9. PMID 15006641 DOI: 10.1016/j.biocel.2003.10.004  0.68
2004 Townsend PA, Cutress RI, Carroll CJ, Lawrence KM, Scarabelli TM, Packham G, Stephanou A, Latchman DS. BAG-1 proteins protect cardiac myocytes from simulated ischemia/reperfusion-induced apoptosis via an alternate mechanism of cell survival independent of the proteasome. The Journal of Biological Chemistry. 279: 20723-8. PMID 14978028 DOI: 10.1074/jbc.M400399200  0.68
2004 Irshad S, Pedley RB, Anderson J, Latchman DS, Budhram-Mahadeo V. The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo. The Journal of Biological Chemistry. 279: 21617-27. PMID 14970234 DOI: 10.1074/jbc.M312506200  0.68
2004 Samady L, Dennis J, Budhram-Mahadeo V, Latchman DS. Activation of CDK4 gene expression in human breast cancer cells by the Brn-3b POU family transcription factor. Cancer Biology & Therapy. 3: 317-23. PMID 14726699  0.68
2004 Haley J, Mason LJ, Nagl S, Giles I, Latchman DS, Isenberg DA, Rahman A. Somatic mutations to arginine residues affect the binding of human monoclonal antibodies to DNA, histones, SmD and Ro antigen. Molecular Immunology. 40: 745-58. PMID 14687932 DOI: 10.1016/j.molimm.2003.10.018  0.68
2004 Muqit MM, Davidson SM, Payne Smith MD, MacCormac LP, Kahns S, Jensen PH, Wood NW, Latchman DS. Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. Human Molecular Genetics. 13: 117-35. PMID 14645198 DOI: 10.1093/hmg/ddh012  0.68
2004 Townsend PA, Scarabelli TM, Davidson SM, Knight RA, Latchman DS, Stephanou A. STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis. The Journal of Biological Chemistry. 279: 5811-20. PMID 14602726 DOI: 10.1074/jbc.M302637200  0.68
2004 Brar BK, Jonassen AK, Egorina EM, Chen A, Negro A, Perrin MH, Mjøs OD, Latchman DS, Lee KF, Vale W. Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart. Endocrinology. 145: 24-35; discussion 21. PMID 12970163 DOI: 10.1210/en.2003-0689  0.68
2004 Latchman DS, Stephanou A. STAT-1 and STAT-3: Closely related transcription factors with antagonistic effects on cell proliferation and apoptosis Current Genomics. 5: 453-457. DOI: 10.2174/1389202043349066  0.68
2003 Kabakov AE, Budagova KR, Bryantsev AL, Latchman DS. Heat shock protein 70 or heat shock protein 27 overexpressed in human endothelial cells during posthypoxic reoxygenation can protect from delayed apoptosis. Cell Stress & Chaperones. 8: 335-47. PMID 15115286 DOI: 10.1379/1466-1268(2003)008<0335:HSPOHS>2.0.CO;2  0.68
2003 Stephanou A, Latchman DS. STAT-1: a novel regulator of apoptosis. International Journal of Experimental Pathology. 84: 239-44. PMID 14748743 DOI: 10.1111/j.0959-9673.2003.00363.x  0.68
2003 Davidson SM, Stephanou A, Latchman DS. FLIP protects cardiomyocytes from apoptosis induced by simulated ischemia/reoxygenation, as demonstrated by short hairpin-induced (shRNA) silencing of FLIP mRNA. Journal of Molecular and Cellular Cardiology. 35: 1359-64. PMID 14596792 DOI: 10.1016/j.yjmcc.2003.08.001  0.68
2003 Lawrence KM, Scarabelli TM, Turtle L, Chanalaris A, Townsend PA, Carroll CJ, Hubank M, Stephanou A, Knight RA, Latchman DS. Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium-insensitive phospholipase A2 gene expression Faseb Journal. 17: 2313-2315. PMID 14563694 DOI: 10.1096/fj.02-0832fje  0.68
2003 Kumar S, Nagl S, Kalsi JK, Ravirajan CT, Athwal D, Latchman DS, Pearl LH, Isenberg DA. Anti-cardiolipin/beta-2 glycoprotein activities co-exist on human anti-DNA antibody light chains. Molecular Immunology. 40: 517-30. PMID 14563371 DOI: 10.1016/S0161-5890(03)00225-6  0.68
2003 Ensor E, Mathews K, Payne Smith MD, Latchman DS. Sensory neurons from mice lacking the Brn-3b POU family transcription factor are resistant to death-inducing stimuli both in vitro and in vivo. Brain Research. Molecular Brain Research. 117: 206-12. PMID 14559155 DOI: 10.1016/S0169-328X(03)00322-X  0.68
2003 Janjua S, Lawrence KM, Ng LL, Latchman DS. The cardioprotective agent urocortin induces expression of CT-1. Cardiovascular Toxicology. 3: 255-62. PMID 14555790 DOI: 10.1385/CT:3:3:255  0.68
2003 Chanalaris A, Lawrence KM, Stephanou A, Knight RD, Hsu SY, Hsueh AJ, Latchman DS. Protective effects of the urocortin homologues stresscopin (SCP) and stresscopin-related peptide (SRP) against hypoxia/reoxygenation injury in rat neonatal cardiomyocytes. Journal of Molecular and Cellular Cardiology. 35: 1295-305. PMID 14519439 DOI: 10.1016/S0022-2828(03)00244-X  0.68
2003 Latchman DS. Herpes simplex virus vectors for Parkinson's disease. International Review of Neurobiology. 55: 223-41. PMID 12968539 DOI: 10.1016/S0074-7742(03)01010-9  0.68
2003 Calissano M, Latchman DS. Functional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor Oncogene. 22: 5408-5414. PMID 12934100 DOI: 10.1038/sj.onc.1206635  0.68
2003 Giles IP, Haley J, Nagl S, Latchman DS, Chen PP, Chukwuocha RU, Isenberg DA, Rahman A. Relative importance of different human aPL derived heavy and light chains in the binding of aPL to cardiolipin. Molecular Immunology. 40: 49-60. PMID 12909130 DOI: 10.1016/S0161-5890(03)00100-7  0.68
2003 Giles IP, Isenberg DA, Latchman DS, Rahman A. How do antiphospholipid antibodies bind β2-glycoprotein I? Arthritis and Rheumatism. 48: 2111-2121. PMID 12905463 DOI: 10.1002/art.11101  0.68
2003 Hargitai J, Lewis H, Boros I, Rácz T, Fiser A, Kurucz I, Benjamin I, Vígh L, Pénzes Z, Csermely P, Latchman DS. Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1 Biochemical and Biophysical Research Communications. 307: 689-695. PMID 12893279 DOI: 10.1016/S0006-291X(03)01254-3  0.68
2003 Sindos M, Ndisang D, Pisal N, Chow C, Singer A, Latchman DS. Measurement of Brn-3a levels in Pap smears provides a novel diagnostic marker for the detection of cervical neoplasia Gynecologic Oncology. 90: 366-371. PMID 12893201 DOI: 10.1016/S0090-8258(03)00261-0  0.68
2003 Mason MRJ, Lieberman AR, Latchman DS, Anderson PN. FKBP12 mRNA expression is upregulated by intrinsic CNS neurons regenerating axons into peripheral nerve grafts in the brain Experimental Neurology. 181: 181-189. PMID 12781991 DOI: 10.1016/S0014-4886(03)00038-4  0.68
2003 Chanalaris A, Sun Y, Latchman DS, Stephanou A. SAG attenuates apoptotic cell death caused by simulated ischaemia/reoxygenation in rat cardiomyocytes Journal of Molecular and Cellular Cardiology. 35: 257-264. PMID 12676540 DOI: 10.1016/S0022-2828(03)00003-8  0.68
2003 Zourlidou A, Payne Smith MD, Latchman DS. Modulation of cell death by α-synuclein is stimulus-dependent in mammalian cells Neuroscience Letters. 340: 234-238. PMID 12672549 DOI: 10.1016/S0304-3940(03)00081-8  0.68
2003 Kalwy SA, Akbar MT, Coffin RS, De Belleroche J, Latchman DS. Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss Molecular Brain Research. 111: 91-103. PMID 12654509 DOI: 10.1016/S0169-328X(02)00692-7  0.68
2003 Akbar MT, Lundberg AM, Liu K, Vidyadaran S, Wells KE, Dolatshad H, Wynn S, Wells DJ, Latchman DS, de Belleroche J. The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death. The Journal of Biological Chemistry. 278: 19956-65. PMID 12639970 DOI: 10.1074/jbc.M207073200  0.68
2003 Giles IP, Haley JD, Nagl S, Isenberg DA, Latchman DS, Rahman A. A systematic analysis of sequences of human antiphospholipid and anti-beta2-glycoprotein I antibodies: the importance of somatic mutations and certain sequence motifs. Seminars in Arthritis and Rheumatism. 32: 246-65. PMID 12621590 DOI: 10.1053/sarh.2003.49994  0.68
2003 Samady L, Costigliola E, MacCormac L, McGrath Y, Cleverley S, Lilley CE, Smith J, Latchman DS, Chain B, Coffin RS. Deletion of the virion host shutoff protein (vhs) from herpes simplex virus (HSV) relieves the viral block to dendritic cell activation: Potential of vhs- HSV vectors for dendritic cell-mediated immunotherapy Journal of Virology. 77: 3768-3776. PMID 12610151 DOI: 10.1128/JVI.77.6.3768-3776.2003  0.68
2003 Gusterson RJ, Jazrawi E, Adcock IM, Latchman DS. The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity Journal of Biological Chemistry. 278: 6838-6847. PMID 12477714 DOI: 10.1074/jbc.M211762200  0.68
2003 Smith J, Thomas SK, Coffin RS, Latchman DS. Examination of the potential interactions between herpes simplex virus vectors and replication-competent virus in vitro and in vivo Gene Therapy and Regulation. 2: 29-47. DOI: 10.1163/156855803762295413  0.68
2003 Latchman DS. Eukaryotic Transcription Factors: Fourth Edition Eukaryotic Transcription Factors: Fourth Edition. 1-364.  0.68
2002 Kumar S, Kalsi JK, Ravirajan CT, Latchman DS, Pearl LH, Isenberg DA. Molecular expression systems for anti-DNA antibodies - 2 Lupus. 11: 833-842. PMID 12529048 DOI: 10.1191/0961203302lu304rr  0.68
2002 Rahman A, Haley J, Latchman DS. Molecular expression systems for anti-DNA antibodies--1. Lupus. 11: 824-32. PMID 12529047 DOI: 10.1191/0961203302lu303oa  0.68
2002 Latchman DS. Herpes simplex virus vectors for gene delivery to a variety of different cell types Current Gene Therapy. 2: 415-426. PMID 12477253  0.68
2002 Perez-Sanchez C, Budhram-Mahadeo VS, Latchman DS. Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter Nucleic Acids Research. 30: 4872-4880. PMID 12433990  0.68
2002 Budhram-Mahadeo V, Morris P, Ndisang D, Irshad S, Lozano G, Pedley B, Latchman DS. The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells Neuroscience Letters. 334: 1-4. PMID 12431761 DOI: 10.1016/S0304-3940(02)00813-3  0.68
2002 Papageorgiou K, Isenberg DA, Latchman DS. Optimisation of herpes simplex virus-based vectors for delivery to human peripheral blood mononuclear cells Journal of Immunological Methods. 270: 235-246. PMID 12379328 DOI: 10.1016/S0022-1759(02)00299-5  0.68
2002 Lawrence KM, Chanalaris A, Scarabelli T, Hubank M, Pasini E, Townsend PA, Comini L, Ferrari R, Tinker A, Stephanou A, Knight RA, Latchman DS. KATP channel gene expression is induced by urocortin and mediates its cardioprotective effect Circulation. 106: 1556-1562. PMID 12234964 DOI: 10.1161/01.CIR.0000028424.02525.AE  0.68
2002 Schulman D, Latchman DS, Yellon DM. Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway American Journal of Physiology - Heart and Circulatory Physiology. 283: H1481-H1488. PMID 12234800  0.68
2002 Janjua S, Stephanou A, Latchman DS. The C-terminal activation domain of the STAT-1 transcription factor is necessary and sufficient for stress-induced apoptosis Cell Death and Differentiation. 9: 1140-1146. PMID 12232802 DOI: 10.1038/sj.cdd.4401082  0.68
2002 Stephanou A, Scarabelli TM, Townsend PA, Bell R, Yellon D, Knight RA, Latchman DS. The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1841-1843. PMID 12223448  0.68
2002 Budram-Mahadeo V, Morris PJ, Latchman DS. The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21CIP1/Waf1 Oncogene. 21: 6123-6131. PMID 12203124 DOI: 10.1038/sj.onc.1205842  0.68
2002 Saurin AT, Pennington DJ, Raat NJH, Latchman DS, Owen MJ, Marber MS. Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts Cardiovascular Research. 55: 672-680. PMID 12160964 DOI: 10.1016/S0008-6363(02)00325-5  0.68
2002 Kabakov AE, Budagova KR, Latchman DS, Kampinga HH. Stressful preconditioning and HSP70 overexpression attenuate proteotoxicity of cellular ATP depletion American Journal of Physiology - Cell Physiology. 283: C521-C534. PMID 12107062  0.68
2002 Scarabelli TM, Pasini E, Stephanou A, Comini L, Curello S, Raddino R, Ferrari R, Knight R, Latchman DS. Urocortin promotes hemodynamic and bioenergetic recovery and improves cell survival in the isolated rat heart exposed to ischemia/reperfusion Journal of the American College of Cardiology. 40: 155-161. PMID 12103270 DOI: 10.1016/S0735-1097(02)01930-7  0.68
2002 Dennis JH, Budhram-Mahadeo V, Latchman DS. Functional interaction between Brn-3a and Src-1 co-activates Brn-3a-mediated transactivation Biochemical and Biophysical Research Communications. 294: 487-495. PMID 12051737 DOI: 10.1016/S0006-291X(02)00500-4  0.68
2002 Railson JE, Liao Z, Brar BK, Buddle JC, Pennica D, Stephanou A, Latchman DS. Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes Cytokine. 17: 243-253. PMID 12027405 DOI: 10.1006/cyto.2001.1011  0.68
2002 Brar BK, Stephanou A, Knight R, Latchman DS. Activation of protein kinase B/Akt by urocortin is essential for its ability to protect cardiac cells against hypoxia/reoxygenation-induced cell death Journal of Molecular and Cellular Cardiology. 34: 483-492. PMID 11991736 DOI: 10.1006/jmcc.2002.1529  0.68
2002 Scarabelli TM, Stephanou A, Pasini E, Comini L, Raddino R, Knight RA, Latchman DS. Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury Circulation Research. 90: 745-748. PMID 11934844 DOI: 10.1161/01.RES.0000015224.07870.9A  0.68
2002 Liao Z, Brar BK, Cai Q, Stephanou A, O'Leary RM, Pennica D, Yellon DM, Latchman DS. Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion Cardiovascular Research. 53: 902-910. PMID 11922900 DOI: 10.1016/S0008-6363(01)00531-4  0.68
2002 Latchman DS. Protection of neuronal and cardiac cells by HSP27 Progress in Molecular and Subcellular Biology. 28: 253-265. PMID 11908064  0.68
2002 Thomas SK, Lilley CE, Latchman DS, Coffin RS. A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV genome Journal of Virology. 76: 4056-4067. PMID 11907244 DOI: 10.1128/JVI.76.8.4056-4067.2002  0.68
2002 Brar BK, Railson J, Stephanou A, Knight RA, Latchman DS. Urocortin increases the expression of heat shock protein 90 in rat cardiac myocytes in a MEK1/2-dependent manner Journal of Endocrinology. 172: 283-293. PMID 11834446 DOI: 10.1677/joe.0.1720283  0.68
2002 Stephanou A, Scarabelli TM, Knight RA, Latchman DS. Antiapoptotic activity of the free caspase recruitment domain of procaspase-9. A novel endogenous rescue pathway in cell death Journal of Biological Chemistry. 277: 13693-13699. PMID 11825888 DOI: 10.1074/jbc.M108530200  0.68
2002 Thomas GR, Latchman DS. The pro-oncoprotein EWS (Ewing's sarcoma protein) interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription Cancer Biology and Therapy. 1: 428-432. DOI: 10.4161/cbt.1.4.23  0.68
2001 Wright MJ, Wightman LML, Latchman DS, Marber MS. In vivo myocardial gene transfer: Optimization and evaluation of intracoronary gene delivery in vivo Gene Therapy. 8: 1833-1839. PMID 11821936 DOI: 10.1038/sj.gt.3301614  0.68
2001 Ripley BJM, Isenberg DA, Latchman DS. Elevated levels of the 90 kDa heat shock protein (hsp90) in SLE correlate with levels of IL-6 and autoantibodies to hsp90 Journal of Autoimmunity. 17: 341-346. PMID 11771959 DOI: 10.1006/jaut.2001.0549  0.68
2001 Latchman DS. Gene therapy with herpes simplex virus vectors: Progress and prospects for clinical neuroscience Neuroscientist. 7: 528-537. PMID 11765130  0.68
2001 Brar BK, Stephanou A, Pennica D, Latchman DS. CT-1 mediated cardioprotection against ischaemic re-oxygenation injury is mediated by PI3 kinase, Akt and MEK1/2 pathways Cytokine. 16: 93-96. PMID 11741348 DOI: 10.1006/cyto.2001.0951  0.68
2001 Sugars KL, Budhram-Mahadeo V, Packham G, Latchman DS. A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53 Nucleic Acids Research. 29: 4530-4540. PMID 11713302  0.68
2001 Smith MDP, Ensor EA, Kinloch RA, Latchman DS. The POU domain transcription factor Brn-3a protects cortical neurons from apoptosis Neuroreport. 12: 3183-3188. PMID 11711852  0.68
2001 Baxter GF, Mocanu MM, Brar BK, Latchman DS, Yellon DM. Cardioprotective effects of transforming growth factor-β1 during early reoxygenation or reperfusion are mediated by p42/p44 MAPK Journal of Cardiovascular Pharmacology. 38: 930-939. PMID 11707697 DOI: 10.1097/00005344-200112000-00015  0.68
2001 Mason LJ, Ravirajan CT, Latchman DS, Isenberg DA. A human anti-dsDNA monoclonal antibody caused hyaline thrombi formation in kidneys of 'leaky' SCID mice Clinical and Experimental Immunology. 126: 137-142. PMID 11678910 DOI: 10.1046/j.1365-2249.2001.01651.x  0.68
2001 Latchman DS. Urocortin protects against ischemic injury via a MAPK-dependent pathway Trends in Cardiovascular Medicine. 11: 167-169. PMID 11597826 DOI: 10.1016/S1050-1738(01)00093-7  0.68
2001 Akbar MT, Wells DJ, Latchman DS, De Belleroche J. Heat shock protein 27 shows a distinctive widespread spatial and temporal pattern of induction in CNS glial and neuronal cells compared to heat shock protein 70 and caspase 3 following kainate administration Molecular Brain Research. 93: 148-163. PMID 11589992 DOI: 10.1016/S0169-328X(01)00199-1  0.68
2001 Schulman D, Latchman DS, Yellon DM. Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury American Journal of Physiology - Heart and Circulatory Physiology. 281: H1630-H1636. PMID 11557553  0.68
2001 Stephanou A, Brar B, Liao Z, Scarabelli T, Knight RA, Latchman DS. Distinct initiator caspases are required for the induction of apoptosis in cardiac myocytes during ischaemia versus reperfusion injury Cell Death and Differentiation. 8: 434-435. PMID 11550095 DOI: 10.1038/sj.cdd.4400846  0.68
2001 Latchman DS. Heat shock proteins and cardiac protection Cardiovascular Research. 51: 637-646. PMID 11530097 DOI: 10.1016/S0008-6363(01)00354-6  0.68
2001 Dennis JH, Budhram-Mahadeo V, Latchman DS. The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells Oncogene. 20: 4961-4971. PMID 11526481 DOI: 10.1038/sj.onc.1204491  0.68
2001 Ndisang D, Budhram-Mahadeo V, Pedley B, Latchman DS. The Brn-3a transcription factor plays a key role in regulating the growth of cervical cancer cells in vivo Oncogene. 20: 4899-4903. PMID 11521202 DOI: 10.1038/sj.onc.1204634  0.68
2001 Freeland K, Boxer LM, Latchman DS. The cyclic AMP response element in the Bcl-2 promoter confers inducibility by hypoxia in neuronal cells Molecular Brain Research. 92: 98-106. PMID 11483246 DOI: 10.1016/S0169-328X(01)00158-9  0.68
2001 Brar BK, Stephanou A, Liao Z, O'Leary RM, Pennica D, Yellon DM, Latchman DS. Cardiotrophin-1 can protect cardiac myocytes from injury when added both prior to simulated ischaemia and at reoxygenation Cardiovascular Research. 51: 265-274. PMID 11470466 DOI: 10.1016/S0008-6363(01)00294-2  0.68
2001 Budhram-Mahadeo V, Moore A, Morris PJ, Ward T, Weber B, Sassone-Corsi P, Latchman DS. The closely related POU family transcription factors Brn-3a and Brn-3b are expressed in distinct cell types in the testis International Journal of Biochemistry and Cell Biology. 33: 1027-1039. PMID 11470235 DOI: 10.1016/S1357-2725(01)00069-3  0.68
2001 Railson JE, Lawrence K, Buddle JC, Pennica D, Latchman DS. Heat shock protein-56 is induced by cardiotrophin-1 and mediates its hypertrophic effect Journal of Molecular and Cellular Cardiology. 33: 1209-1221. PMID 11444924 DOI: 10.1006/jmcc.2001.1384  0.68
2001 Stephanou A, Scarabelli TM, Brar BK, Nakanishi Y, Matsumura M, Knight RA, Latchman DS. Induction of Apoptosis and Fas Receptor/Fas Ligand Expression by Ischemia/Reperfusion in Cardiac Myocytes Requires Serine 727 of the STAT-1 Transcription Factor but Not Tyrosine 701 Journal of Biological Chemistry. 276: 28340-28347. PMID 11309387 DOI: 10.1074/jbc.M101177200  0.68
2001 Lilley CE, Groutsi F, Han Z, Palmer JA, Anderson PN, Latchman DS, Coffin RS. Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo Journal of Virology. 75: 4343-4356. PMID 11287583 DOI: 10.1128/JVI.75.9.4343-4356.2001  0.68
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