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David S. Latchman, Ph.D. - Publications

Affiliations: 
Molecular Pathology University College London, London, United Kingdom 
Area:
Gene Regulation
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Year Citation  Score
2016 Hudson CD, Morris PJ, Latchman DS, Budhram-Mahadeo VS. Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate. The Journal of Biological Chemistry. 291: 15909. PMID 27451431 DOI: 10.1074/Jbc.A116.408679  0.365
2013 Carroll CJ, Sayan BS, Bailey SG, McCormick J, Stephanou A, Latchman DS, Townsend PA. Regulation of myocardial interleukin-6 expression by p53 and STAT1. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 542-8. PMID 23675777 DOI: 10.1089/Jir.2012.0165  0.309
2012 McCormick J, Knight RA, Barry SP, Scarabelli TM, Abounit K, Latchman DS, Stephanou A. Autophagy in the stress-induced myocardium. Frontiers in Bioscience (Elite Edition). 4: 2131-2141. PMID 22202025 DOI: 10.2741/530  0.322
2012 Latchman DS. HSV-Cellular Protein Interactions. Methods in Molecular Medicine. 10: 257-72. PMID 21374235 DOI: 10.1385/0-89603-347-3:257  0.388
2010 Dimco G, Knight RA, Latchman DS, Stephanou A. STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest Cell Cycle. 9: 4638-4649. PMID 21084836 DOI: 10.4161/Cc.9.23.13955  0.31
2010 Barry SP, Lawrence KM, McCormick J, Soond SM, Hubank M, Eaton S, Sivarajah A, Scarabelli TM, Knight RA, Thiemermann C, Latchman DS, Townsend PA, Stephanou A. New targets of urocortin-mediated cardioprotection Journal of Molecular Endocrinology. 45: 69-85. PMID 20501665 DOI: 10.1677/Jme-09-0148  0.369
2010 Gascoyne DM, Dunne J, Behjati S, Sebire NJ, Anderson J, Latchman DS. EWS/ETS proteins promote expression and regulate function of the homeodomain transcription factor BRN3A Oncogene. 29: 3134-3145. PMID 20348952 DOI: 10.1038/Onc.2010.72  0.367
2010 Ripley BJM, Fujimoto M, Serada S, Ohkawara T, Nishikawa T, Terabe F, Matsukawa Y, Stephanou A, Knight RA, Isenberg DA, Latchman DS, Kishimoto T, Naka T. Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression International Immunology. 22: 359-366. PMID 20190037 DOI: 10.1093/Intimm/Dxq015  0.342
2010 van der Weerd L, Tariq Akbar M, Aron Badin R, Valentim LM, Thomas DL, Wells DJ, Latchman DS, Gadian DG, Lythgoe MF, de Belleroche JS. Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 849-56. PMID 19997117 DOI: 10.1038/Jcbfm.2009.249  0.322
2009 Barry SP, Townsend PA, McCormick J, Knight RA, Scarabelli TM, Latchman DS, Stephanou A. STAT3 deletion sensitizes cells to oxidative stress Biochemical and Biophysical Research Communications. 385: 324-329. PMID 19450559 DOI: 10.1016/J.Bbrc.2009.05.051  0.338
2009 Giles I, Pericleous C, Liu X, Ehsanullah J, Clarke L, Brogan P, Newton-West M, Swerlick R, Lambrianides A, Chen P, Latchman D, Isenberg D, Pierangeli S, Rahman A. Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions Journal of Immunology. 182: 4836-4843. PMID 19342662 DOI: 10.4049/Jimmunol.0804241  0.307
2009 Berwick DC, Calissano M, Corness JD, Cook SJ, Latchman DS. Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation. Brain Research. 1256: 8-18. PMID 19135033 DOI: 10.1016/J.Brainres.2008.12.009  0.338
2009 Scarabelli TM, Mariotto S, Abdel-Azeim S, Shoji K, Darra E, Stephanou A, Chen-Scarabelli C, Marechal JD, Knight R, Ciampa A, Saravolatz L, de Prati AC, Yuan Z, Cavalieri E, Menegazzi M, ... Latchman D, et al. Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion-induced injury Febs Letters. 583: 531-541. PMID 19116149 DOI: 10.1016/J.Febslet.2008.12.037  0.308
2008 Scarabelli TM, Townsend PA, Chen Scarabelli C, Yuan Z, McCauley RB, Di Rezze J, Patel D, Putt J, Allebban Z, Abboud J, Chilukuri K, Gardin J, Saravolatz L, Knight RA, Latchman DS, et al. Amino acid supplementation differentially modulates STAT1 and STAT3 activation in the myocardium exposed to ischemia/reperfusion injury. The American Journal of Cardiology. 101: 63E-68E. PMID 18514629 DOI: 10.1016/J.Amjcard.2008.03.003  0.309
2008 Soond SM, Barry SP, Melino G, Knight RA, Latchman DS, Stephanou A. p73-mediated transcriptional activity is negatively regulated by polo-like kinase Cell Cycle. 7: 1214-1223. PMID 18418051 DOI: 10.4161/Cc.7.9.5777  0.371
2008 Soond SM, Townsend PA, Barry SP, Knight RA, Latchman DS, Stephanou A. ERK and the F-box protein βTRCP target STAT1 for degradation Journal of Biological Chemistry. 283: 16077-16083. PMID 18378670 DOI: 10.1074/Jbc.M800384200  0.34
2008 Farooqui-Kabir SR, Diss JKJ, Henderson D, Marber MS, Latchman DS, Budhram-Mahadeo V, Heads RJ. Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression Cell Stress and Chaperones. 13: 297-312. PMID 18368538 DOI: 10.1007/S12192-008-0028-2  0.365
2008 Sharp PS, Akbar MT, Bouri S, Senda A, Joshi K, Chen HJ, Latchman DS, Wells DJ, de Belleroche J. Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression Neurobiology of Disease. 30: 42-55. PMID 18255302 DOI: 10.1016/J.Nbd.2007.12.002  0.301
2008 Diss JK, Calissano M, Gascoyne D, Djamgoz MB, Latchman DS. Identification and characterization of the promoter region of the Nav1.7 voltage-gated sodium channel gene (SCN9A). Molecular and Cellular Neurosciences. 37: 537-47. PMID 18249135 DOI: 10.1016/J.Mcn.2007.12.002  0.338
2008 Budhram-Mahadeo VS, Irshad S, Bowen S, Lee SA, Samady L, Tonini GP, Latchman DS. Proliferation-associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cells Oncogene. 27: 145-154. PMID 17637757 DOI: 10.1038/Sj.Onc.1210621  0.302
2007 Calissano M, Diss JKJ, Latchman DS. Post-transcriptional regulation of the Brn-3b transcription factor in differentiating neuroblastoma cells Febs Letters. 581: 2490-2496. PMID 17490655 DOI: 10.1016/J.Febslet.2007.04.066  0.359
2007 Zourlidou A, Gidalevitz T, Kristiansen M, Landles C, Woodman B, Wells DJ, Latchman DS, de Belleroche J, Tabrizi SJ, Morimoto RI, Bates GP. Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation. Human Molecular Genetics. 16: 1078-90. PMID 17360721 DOI: 10.1093/Hmg/Ddm057  0.317
2007 Soond SM, Carroll C, Townsend PA, Sayan E, Melino G, Behrmann I, Knight RA, Latchman DS, Stephanou A. STAT1 regulates p73-mediated Bax gene expression Febs Letters. 581: 1217-1226. PMID 17346710 DOI: 10.1016/J.Febslet.2007.02.049  0.328
2007 Francis YI, Diss JKJ, Kariti M, Stephanou A, Latchman DS. p300 activation by Presenilin 1 but not by its M146L mutant Neuroscience Letters. 413: 137-140. PMID 17197080 DOI: 10.1016/J.Neulet.2006.11.036  0.308
2006 Budhram-Mahadeo VS, Bowen S, Lee S, Perez-Sanchez C, Ensor E, Morris PJ, Latchman DS. Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression Nucleic Acids Research. 34: 6640-6652. PMID 17145718 DOI: 10.1093/Nar/Gkl878  0.349
2006 McCormick J, Barry SP, Sivarajah A, Stefanutti G, Townsend PA, Lawrence KM, Eaton S, Knight RA, Thiemermann C, Latchman DS, Stephanou A. Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2115-7. PMID 16935931 DOI: 10.1096/Fj.06-6188Fje  0.317
2006 Soond SM, Latchman DS, Stephanou A. STAT signalling in the heart and cardioprotection Expert Reviews in Molecular Medicine. 8: 1-16. PMID 16836797 DOI: 10.1017/S1462399406000032  0.312
2006 Francis YI, Stephanou A, Latchman DS. CREB-binding protein activation by presenilin 1 but not by its M146L mutant Neuroreport. 17: 917-921. PMID 16738488 DOI: 10.1097/01.Wnr.0000220137.06542.A0  0.36
2006 Valentim L, Laurence KM, Townsend PA, Carroll CJ, Soond S, Scarabelli TM, Knight RA, Latchman DS, Stephanou A. Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury Journal of Molecular and Cellular Cardiology. 40: 846-852. PMID 16697404 DOI: 10.1016/J.Yjmcc.2006.03.428  0.32
2006 Kabakov AE, Malyutina YV, Latchman DS. Hsf1-mediated stress response can transiently enhance cellular radioresistance Radiation Research. 165: 410-423. PMID 16579653 DOI: 10.1667/Rr3514.1  0.352
2006 Scarabelli TM, Knight R, Stephanou A, Townsend P, Chen-Scarabelli C, Lawrence K, Gottlieb R, Latchman D, Narula J. Clinical implications of apoptosis in ischemic myocardium Current Problems in Cardiology. 31: 181-264. PMID 16503249 DOI: 10.1016/J.Cpcardiol.2005.11.002  0.314
2006 Diss JK, Faulkes DJ, Walker MM, Patel A, Foster CS, Budhram-Mahadeo V, Djamgoz MB, Latchman DS. Brn-3a neuronal transcription factor functional expression in human prostate cancer. Prostate Cancer and Prostatic Diseases. 9: 83-91. PMID 16276351 DOI: 10.1038/Sj.Pcan.4500837  0.363
2006 Samady L, Faulkes DJ, Budhram-Mahadeo V, Ndisang D, Potter E, Brabant G, Latchman DS. The Brn-3b POU family transcription factor represses plakoglobin gene expression in human breast cancer cells International Journal of Cancer. 118: 869-878. PMID 16152597 DOI: 10.1002/Ijc.21435  0.344
2006 Badin RA, Lythgoe MF, van der Weerd L, Thomas DL, Gadian DG, Latchman DS. Neuroprotective effects of virally delivered HSPs in experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 371-81. PMID 16079790 DOI: 10.1038/Sj.Jcbfm.9600190  0.318
2005 Mason LJ, Lambrianides A, Haley JD, Manson JJ, Latchman DS, Isenberg DA, Rahman A. Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity. Arthritis Research & Therapy. 7: R971-83. PMID 16207338 DOI: 10.1186/Ar1768  0.302
2005 Calissano M, Faulkes D, Latchman DS. Phosphorylation of the Brn-3a transcription factor is modulated during differentiation and regulates its functional activity Molecular Brain Research. 141: 10-18. PMID 16126301 DOI: 10.1016/J.Molbrainres.2005.07.013  0.367
2005 Patel YJK, Payne Smith MD, De Belleroche J, Latchman DS. Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells Molecular Brain Research. 134: 256-274. PMID 15836922 DOI: 10.1016/J.Molbrainres.2004.10.028  0.338
2005 Lee SA, Ndisang D, Patel C, Dennis JH, Faulkes DJ, D'Arrigo C, Samady L, Farooqui-Kabir S, Heads RJ, Latchman DS, Budhram-Mahadeo VS. Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in cancer and is required for maximal activation of the HSP-27 promoter Cancer Research. 65: 3072-3080. PMID 15833836 DOI: 10.1158/0008-5472.Can-04-2865  0.62
2005 Ripley BJM, Rahman MA, Isenberg DA, Latchman DS. Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies to Brn-3 and overexpression of Hsp90 Arthritis and Rheumatism. 52: 1171-1179. PMID 15818685 DOI: 10.1002/Art.21000  0.37
2005 Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage Journal of Cell Science. 118: 1629-1639. PMID 15784679 DOI: 10.1242/Jcs.01728  0.316
2005 Davidson SM, Townsend PA, Carroll C, Yurek-George A, Balasubramanyam K, Kundu TK, Stephanou A, Packham G, Ganesan A, Latchman DS. The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin Chembiochem. 6: 162-170. PMID 15593114 DOI: 10.1002/Cbic.200400246  0.331
2005 Townsend PA, Stephanou A, Packham G, Latchman DS. BAG-1: A multi-functional pro-survival molecule International Journal of Biochemistry and Cell Biology. 37: 251-259. PMID 15474970 DOI: 10.1016/J.Biocel.2004.03.016  0.348
2004 Kabakov AE, Budagova KR, Malyutina YV, Latchman DS, Csermely P. Pharmacological attenuation of apoptosis in reoxygenated endothelial cells. Cellular and Molecular Life Sciences : Cmls. 61: 3076-86. PMID 15583868 DOI: 10.1007/S00018-004-4204-Y  0.33
2004 Munarriz E, Barcaroli D, Stephanou A, Townsend PA, Maisse C, Terrinoni A, Neale MH, Martin SJ, Latchman DS, Knight RA, Melino G, De Laurenzi V. PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73. Molecular and Cellular Biology. 24: 10593-610. PMID 15572666 DOI: 10.1128/Mcb.24.24.10593-10610.2004  0.312
2004 MacCormac LP, Muqit MM, Faulkes DJ, Wood NW, Latchman DS. Reduction in endogenous parkin levels renders glial cells sensitive to both caspase-dependent and caspase-independent cell death. The European Journal of Neuroscience. 20: 2038-48. PMID 15450083 DOI: 10.1111/J.1460-9568.2004.03659.X  0.349
2004 Lawrence KM, Townsend PA, Davidson SM, Carroll CJ, Eaton S, Hubank M, Knight RA, Stephanou A, Latchman DS. The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage. Biochemical and Biophysical Research Communications. 321: 479-86. PMID 15358201 DOI: 10.1016/J.Bbrc.2004.06.170  0.328
2004 Townsend PA, Scarabelli TM, Pasini E, Gitti G, Menegazzi M, Suzuki H, Knight RA, Latchman DS, Stephanou A. Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1621-3. PMID 15319365 DOI: 10.1096/Fj.04-1716Fje  0.325
2004 West DA, Valentim LM, Lythgoe MF, Stephanou A, Proctor E, van der Weerd L, Ordidge RJ, Latchman DS, Gadian DG. MR image-guided investigation of regional signal transducers and activators of transcription-1 activation in a rat model of focal cerebral ischemia. Neuroscience. 127: 333-9. PMID 15262323 DOI: 10.1016/J.Neuroscience.2004.05.022  0.312
2004 Faulkes DJ, Ensor E, Le Rouzic E, Latchman DS. Distinct domains of Brn-3a regulate apoptosis and neurite outgrowth in vivo. Neuroreport. 15: 1421-5. PMID 15194866 DOI: 10.1097/01.Wnr.0000129371.81377.05  0.318
2004 Thomas GR, Faulkes DJ, Gascoyne D, Latchman DS. EWS differentially activates transcription of the Brn-3a long and short isoform mRNAs from distinct promoters Biochemical and Biophysical Research Communications. 318: 1045-1051. PMID 15147979 DOI: 10.1016/J.Bbrc.2004.04.134  0.357
2004 Parkinson EJ, Townsend PA, Stephanou A, Latchman DS, Eaton S, Pierro A. The Protective Effect of Moderate Hypothermia during Intestinal Ischemia-Reperfusion is Associated with Modification of Hepatic Transcription Factor Activation Journal of Pediatric Surgery. 39: 696-701. PMID 15137002 DOI: 10.1016/J.Jpedsurg.2004.01.025  0.314
2004 Calissano M, Ensor E, Brown DR, Latchman DS. Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors. Neuroreport. 15: 483-6. PMID 15094508 DOI: 10.1097/00001756-200403010-00020  0.382
2004 Gascoyne DM, Thomas GR, Latchman DS. The effects of Brn-3a on neuronal differentiation and apoptosis are differentially modulated by EWS and its oncogenic derivative EWS/Fli-1. Oncogene. 23: 3830-40. PMID 15021903 DOI: 10.1038/Sj.Onc.1207497  0.372
2004 Alsbury S, Papageorgiou K, Latchman DS. Heat shock proteins can protect aged human and rodent cells from different stressful stimuli. Mechanisms of Ageing and Development. 125: 201-9. PMID 15013664 DOI: 10.1016/J.Mad.2003.11.015  0.321
2004 Zourlidou A, Payne Smith MD, Latchman DS. HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells. Journal of Neurochemistry. 88: 1439-48. PMID 15009645 DOI: 10.1046/J.1471-4159.2003.02273.X  0.334
2004 Gusterson RJ, Yuan LW, Latchman DS. Distinct serine residues in CBP and p300 are necessary for their activation by phenylephrine. The International Journal of Biochemistry & Cell Biology. 36: 893-9. PMID 15006641 DOI: 10.1016/J.Biocel.2003.10.004  0.327
2004 Townsend PA, Cutress RI, Carroll CJ, Lawrence KM, Scarabelli TM, Packham G, Stephanou A, Latchman DS. BAG-1 proteins protect cardiac myocytes from simulated ischemia/reperfusion-induced apoptosis via an alternate mechanism of cell survival independent of the proteasome. The Journal of Biological Chemistry. 279: 20723-8. PMID 14978028 DOI: 10.1074/Jbc.M400399200  0.365
2004 Samady L, Dennis J, Budhram-Mahadeo V, Latchman DS. Activation of CDK4 gene expression in human breast cancer cells by the Brn-3b POU family transcription factor. Cancer Biology & Therapy. 3: 317-23. PMID 14726699 DOI: 10.4161/Cbt.3.3.698  0.607
2004 Haley J, Mason LJ, Nagl S, Giles I, Latchman DS, Isenberg DA, Rahman A. Somatic mutations to arginine residues affect the binding of human monoclonal antibodies to DNA, histones, SmD and Ro antigen. Molecular Immunology. 40: 745-58. PMID 14687932 DOI: 10.1016/J.Molimm.2003.10.018  0.304
2004 Muqit MM, Davidson SM, Payne Smith MD, MacCormac LP, Kahns S, Jensen PH, Wood NW, Latchman DS. Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. Human Molecular Genetics. 13: 117-35. PMID 14645198 DOI: 10.1093/Hmg/Ddh012  0.321
2004 Townsend PA, Scarabelli TM, Davidson SM, Knight RA, Latchman DS, Stephanou A. STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis. The Journal of Biological Chemistry. 279: 5811-20. PMID 14602726 DOI: 10.1074/Jbc.M302637200  0.349
2004 Irshad S, Pedley RB, Anderson J, Latchman DS, Budhram-Mahadeo VS. The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo Journal of Biological Chemistry. 279: 21617-21627. DOI: 10.1074/Jbc.A114.312506  0.324
2003 Kabakov AE, Budagova KR, Bryantsev AL, Latchman DS. Heat shock protein 70 or heat shock protein 27 overexpressed in human endothelial cells during posthypoxic reoxygenation can protect from delayed apoptosis. Cell Stress & Chaperones. 8: 335-47. PMID 15115286 DOI: 10.1379/1466-1268(2003)008<0335:Hspohs>2.0.Co;2  0.336
2003 Stephanou A, Latchman DS. STAT-1: a novel regulator of apoptosis. International Journal of Experimental Pathology. 84: 239-44. PMID 14748743 DOI: 10.1111/J.0959-9673.2003.00363.X  0.381
2003 Davidson SM, Stephanou A, Latchman DS. FLIP protects cardiomyocytes from apoptosis induced by simulated ischemia/reoxygenation, as demonstrated by short hairpin-induced (shRNA) silencing of FLIP mRNA. Journal of Molecular and Cellular Cardiology. 35: 1359-64. PMID 14596792 DOI: 10.1016/J.Yjmcc.2003.08.001  0.314
2003 Lawrence KM, Scarabelli TM, Turtle L, Chanalaris A, Townsend PA, Carroll CJ, Hubank M, Stephanou A, Knight RA, Latchman DS. Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium-insensitive phospholipase A2 gene expression Faseb Journal. 17: 2313-2315. PMID 14563694 DOI: 10.1096/Fj.02-0832Fje  0.321
2003 Ensor E, Mathews K, Payne Smith MD, Latchman DS. Sensory neurons from mice lacking the Brn-3b POU family transcription factor are resistant to death-inducing stimuli both in vitro and in vivo. Brain Research. Molecular Brain Research. 117: 206-12. PMID 14559155 DOI: 10.1016/S0169-328X(03)00322-X  0.352
2003 Janjua S, Lawrence KM, Ng LL, Latchman DS. The cardioprotective agent urocortin induces expression of CT-1. Cardiovascular Toxicology. 3: 255-62. PMID 14555790 DOI: 10.1385/Ct:3:3:255  0.334
2003 Latchman DS. Herpes simplex virus vectors for Parkinson's disease. International Review of Neurobiology. 55: 223-41. PMID 12968539 DOI: 10.1016/S0074-7742(03)01010-9  0.331
2003 Calissano M, Latchman DS. Functional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor Oncogene. 22: 5408-5414. PMID 12934100 DOI: 10.1038/Sj.Onc.1206635  0.36
2003 Hargitai J, Lewis H, Boros I, Rácz T, Fiser A, Kurucz I, Benjamin I, Vígh L, Pénzes Z, Csermely P, Latchman DS. Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1 Biochemical and Biophysical Research Communications. 307: 689-695. PMID 12893279 DOI: 10.1016/S0006-291X(03)01254-3  0.34
2003 Zourlidou A, Payne Smith MD, Latchman DS. Modulation of cell death by α-synuclein is stimulus-dependent in mammalian cells Neuroscience Letters. 340: 234-238. PMID 12672549 DOI: 10.1016/S0304-3940(03)00081-8  0.302
2003 Kalwy SA, Akbar MT, Coffin RS, De Belleroche J, Latchman DS. Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss Molecular Brain Research. 111: 91-103. PMID 12654509 DOI: 10.1016/S0169-328X(02)00692-7  0.373
2003 Akbar MT, Lundberg AM, Liu K, Vidyadaran S, Wells KE, Dolatshad H, Wynn S, Wells DJ, Latchman DS, de Belleroche J. The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death. The Journal of Biological Chemistry. 278: 19956-65. PMID 12639970 DOI: 10.1074/Jbc.M207073200  0.346
2003 Patel Y, Collaco Moraes Y, Latchman D, Coffin R, de Belleroche J. Neuroprotective effects of copper/zinc-dependent superoxide dismutase against a wide variety of death-inducing stimuli and proapoptotic effect of familial amyotrophic lateral sclerosis mutations. Brain Research. Molecular Brain Research. 109: 189-97. PMID 12531528 DOI: 10.1016/S0169-328X(02)00560-0  0.337
2003 Gusterson RJ, Jazrawi E, Adcock IM, Latchman DS. The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity Journal of Biological Chemistry. 278: 6838-6847. PMID 12477714 DOI: 10.1074/Jbc.M211762200  0.371
2002 Latchman DS. Herpes simplex virus vectors for gene delivery to a variety of different cell types Current Gene Therapy. 2: 415-426. PMID 12477253 DOI: 10.2174/1566523023347698  0.348
2002 Perez-Sanchez C, Budhram-Mahadeo VS, Latchman DS. Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter Nucleic Acids Research. 30: 4872-4880. PMID 12433990 DOI: 10.1093/Nar/Gkf610  0.311
2002 Budhram-Mahadeo V, Morris P, Ndisang D, Irshad S, Lozano G, Pedley B, Latchman DS. The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells Neuroscience Letters. 334: 1-4. PMID 12431761 DOI: 10.1016/S0304-3940(02)00813-3  0.374
2002 Papageorgiou K, Isenberg DA, Latchman DS. Optimisation of herpes simplex virus-based vectors for delivery to human peripheral blood mononuclear cells Journal of Immunological Methods. 270: 235-246. PMID 12379328 DOI: 10.1016/S0022-1759(02)00299-5  0.312
2002 Stephanou A, Scarabelli TM, Townsend PA, Bell R, Yellon D, Knight RA, Latchman DS. The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1841-1843. PMID 12223448 DOI: 10.1096/Fj.02-0150Fje  0.32
2002 Budram-Mahadeo V, Morris PJ, Latchman DS. The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21CIP1/Waf1 Oncogene. 21: 6123-6131. PMID 12203124 DOI: 10.1038/Sj.Onc.1205842  0.353
2002 Kabakov AE, Budagova KR, Latchman DS, Kampinga HH. Stressful preconditioning and HSP70 overexpression attenuate proteotoxicity of cellular ATP depletion American Journal of Physiology - Cell Physiology. 283: C521-C534. PMID 12107062 DOI: 10.1152/Ajpcell.00503.2001  0.326
2002 Dennis JH, Budhram-Mahadeo V, Latchman DS. Functional interaction between Brn-3a and Src-1 co-activates Brn-3a-mediated transactivation Biochemical and Biophysical Research Communications. 294: 487-495. PMID 12051737 DOI: 10.1016/S0006-291X(02)00500-4  0.615
2002 Brar BK, Stephanou A, Knight R, Latchman DS. Activation of protein kinase B/Akt by urocortin is essential for its ability to protect cardiac cells against hypoxia/reoxygenation-induced cell death Journal of Molecular and Cellular Cardiology. 34: 483-492. PMID 11991736 DOI: 10.1006/Jmcc.2002.1529  0.302
2002 Latchman DS. Protection of neuronal and cardiac cells by HSP27 Progress in Molecular and Subcellular Biology. 28: 253-265. PMID 11908064 DOI: 10.1007/978-3-642-56348-5_14  0.343
2002 Thomas SK, Lilley CE, Latchman DS, Coffin RS. A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV genome Journal of Virology. 76: 4056-4067. PMID 11907244 DOI: 10.1128/Jvi.76.8.4056-4067.2002  0.372
2002 Stephanou A, Scarabelli TM, Knight RA, Latchman DS. Antiapoptotic activity of the free caspase recruitment domain of procaspase-9. A novel endogenous rescue pathway in cell death Journal of Biological Chemistry. 277: 13693-13699. PMID 11825888 DOI: 10.1074/Jbc.M108530200  0.344
2002 Thomas GR, Latchman DS. The pro-oncoprotein EWS (Ewing's sarcoma protein) interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription Cancer Biology and Therapy. 1: 428-432. DOI: 10.4161/Cbt.1.4.23  0.376
2001 Latchman DS. Gene therapy with herpes simplex virus vectors: Progress and prospects for clinical neuroscience Neuroscientist. 7: 528-537. PMID 11765130 DOI: 10.1177/107385840100700609  0.315
2001 Sugars KL, Budhram-Mahadeo V, Packham G, Latchman DS. A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53 Nucleic Acids Research. 29: 4530-4540. PMID 11713302 DOI: 10.1093/Nar/29.22.4530  0.348
2001 Smith MDP, Ensor EA, Kinloch RA, Latchman DS. The POU domain transcription factor Brn-3a protects cortical neurons from apoptosis Neuroreport. 12: 3183-3188. PMID 11711852 DOI: 10.1097/00001756-200110290-00008  0.327
2001 Latchman DS. Urocortin protects against ischemic injury via a MAPK-dependent pathway Trends in Cardiovascular Medicine. 11: 167-169. PMID 11597826 DOI: 10.1016/S1050-1738(01)00093-7  0.322
2001 Akbar MT, Wells DJ, Latchman DS, De Belleroche J. Heat shock protein 27 shows a distinctive widespread spatial and temporal pattern of induction in CNS glial and neuronal cells compared to heat shock protein 70 and caspase 3 following kainate administration Molecular Brain Research. 93: 148-163. PMID 11589992 DOI: 10.1016/S0169-328X(01)00199-1  0.326
2001 Latchman DS. Heat shock proteins and cardiac protection Cardiovascular Research. 51: 637-646. PMID 11530097 DOI: 10.1016/S0008-6363(01)00354-6  0.359
2001 Dennis JH, Budhram-Mahadeo V, Latchman DS. The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells Oncogene. 20: 4961-4971. PMID 11526481 DOI: 10.1038/Sj.Onc.1204491  0.617
2001 Ndisang D, Budhram-Mahadeo V, Pedley B, Latchman DS. The Brn-3a transcription factor plays a key role in regulating the growth of cervical cancer cells in vivo Oncogene. 20: 4899-4903. PMID 11521202 DOI: 10.1038/Sj.Onc.1204634  0.358
2001 Freeland K, Boxer LM, Latchman DS. The cyclic AMP response element in the Bcl-2 promoter confers inducibility by hypoxia in neuronal cells Molecular Brain Research. 92: 98-106. PMID 11483246 DOI: 10.1016/S0169-328X(01)00158-9  0.379
2001 Budhram-Mahadeo V, Moore A, Morris PJ, Ward T, Weber B, Sassone-Corsi P, Latchman DS. The closely related POU family transcription factors Brn-3a and Brn-3b are expressed in distinct cell types in the testis International Journal of Biochemistry and Cell Biology. 33: 1027-1039. PMID 11470235 DOI: 10.1016/S1357-2725(01)00069-3  0.366
2001 Latchman DS. Transcription factors as potential targets for therapeutic drugs. Current Pharmaceutical Biotechnology. 1: 57-61. PMID 11467361 DOI: 10.2174/1389201003379022  0.312
2001 Railson JE, Lawrence K, Buddle JC, Pennica D, Latchman DS. Heat shock protein-56 is induced by cardiotrophin-1 and mediates its hypertrophic effect Journal of Molecular and Cellular Cardiology. 33: 1209-1221. PMID 11444924 DOI: 10.1006/Jmcc.2001.1384  0.335
2001 Wright MJ, Wightman LM, Lilley C, de Alwis M, Hart SL, Miller A, Coffin RS, Thrasher A, Latchman DS, Marber MS. In vivo myocardial gene transfer: optimization, evaluation and direct comparison of gene transfer vectors. Basic Research in Cardiology. 96: 227-36. PMID 11403416 DOI: 10.1007/S003950170053  0.31
2001 Latchman DS. Transcription factors: bound to activate or repress. Trends in Biochemical Sciences. 26: 211-3. PMID 11295539 DOI: 10.1016/S0968-0004(01)01812-6  0.345
2001 Lilley CE, Groutsi F, Han Z, Palmer JA, Anderson PN, Latchman DS, Coffin RS. Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo Journal of Virology. 75: 4343-4356. PMID 11287583 DOI: 10.1128/Jvi.75.9.4343-4356.2001  0.331
2001 Smith MD, Melton LA, Ensor EA, Packham G, Anderson P, Kinloch RA, Latchman DS. Brn-3a activates the expression of Bcl-x(L) and promotes neuronal survival in vivo as well as in vitro. Molecular and Cellular Neurosciences. 17: 460-70. PMID 11273642 DOI: 10.1006/Mcne.2000.0927  0.343
2001 Latchman DS. Gene delivery and gene therapy with herpes simplex virus-based vectors. Gene. 264: 1-9. PMID 11245972 DOI: 10.1016/S0378-1119(01)00322-5  0.319
2001 Latchman DS, Coffin RS. Viral vectors for gene therapy in Parkinson's disease. Reviews in the Neurosciences. 12: 69-78. PMID 11236066 DOI: 10.1515/Revneuro.2001.12.1.69  0.323
2001 Railson J, Lawrence K, Stephanou A, Brar B, Pennica D, Latchman D. Cardiotrophin-1 reduces stress-induced heat shock protein production in cardiac myocytes. Cytokine. 12: 1741-4. PMID 11052830 DOI: 10.1006/Cyto.2000.0778  0.326
2001 Latchman DS. Gene therapy using herpes simplex virus-based vectors. Histology and Histopathology. 15: 1253-9. PMID 11005249 DOI: 10.14670/Hh-15.1253  0.312
2000 Ensor E, Smith MD, Latchman DS. The BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosis. The Journal of Biological Chemistry. 276: 5204-12. PMID 11053412 DOI: 10.1074/Jbc.M007068200  0.33
2000 Mockridge JW, Benton EC, Andreeva LV, Latchman DS, Marber MS, Heads RJ. IGF-1 regulates cardiac fibroblast apoptosis induced by osmotic stress. Biochemical and Biophysical Research Communications. 273: 322-7. PMID 10873605 DOI: 10.1006/Bbrc.2000.2934  0.315
2000 Palmer JA, Branston RH, Lilley CE, Robinson MJ, Groutsi F, Smith J, Latchman DS, Coffin RS. Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system. Journal of Virology. 74: 5604-18. PMID 10823868 DOI: 10.1128/Jvi.74.12.5604-5618.2000  0.306
2000 Latchman DS. Cardiotrophin-1: a novel cytokine and its effects in the heart and other tissues. Pharmacology & Therapeutics. 85: 29-37. PMID 10674712 DOI: 10.1016/S0163-7258(99)00049-2  0.328
2000 Brar BK, Stephanou A, Okosi A, Lawrence KM, Knight RA, Marber MS, Latchman DS. CRH-like peptides protect cardiac myocytes from lethal ischaemic injury. Molecular and Cellular Endocrinology. 158: 55-63. PMID 10630405 DOI: 10.1016/S0303-7207(99)00183-5  0.31
2000 Budhram-Mahadeo V, Ndisang D, Ward T, Weber BL, Latchman DS. The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells. Oncogene. 18: 6684-91. PMID 10597274 DOI: 10.1038/Sj.Onc.1203072  0.352
2000 Ripley BJ, Stephanou A, Isenberg DA, Latchman DS. Interleukin-10 activates heat-shock protein 90beta gene expression. Immunology. 97: 226-31. PMID 10447736 DOI: 10.1046/J.1365-2567.1999.00773.X  0.313
2000 FREELAND K, LIU Y, LATCHMAN DS. Distinct signalling pathways mediate the cAMP response element (CRE)-dependent activation of the calcitonin gene-related peptide gene promoter by cAMP and nerve growth factor Biochemical Journal. 345: 233-238. DOI: 10.1042/Bj3450233  0.344
1999 Smith MD, Ensor EA, Stohl L, Wagner JA, Latchman DS. Regulation of NGFI-A (Egr-1) gene expression by the POU domain transcription factor Brn-3a Molecular Brain Research. 74: 117-125. PMID 10640682 DOI: 10.1016/S0169-328X(99)00271-5  0.391
1999 Ndisang D, Budhram-Mahadeo V, Latchman DS. The Brn-3a transcription factor plays a critical role in regulating human papilloma virus gene expression and determining the growth characteristics of cervical cancer cells. The Journal of Biological Chemistry. 274: 28521-7. PMID 10497216 DOI: 10.1074/Jbc.274.40.28521  0.312
1999 Thomas SK, Lilley CE, Latchman DS, Coffin RS. Equine herpesvirus 1 gene 12 can substitute for vmw65 in the growth of herpes simplex virus (HSV) type 1, allowing the generation of optimized cell lines for the propagation of HSV vectors with multiple immediate-early gene defects Journal of Virology. 73: 7399-7409. PMID 10438830 DOI: 10.1128/Jvi.73.9.7399-7409.1999  0.349
1999 Latchman DS. Regulation of DNA virus transcription by cellular POU family transcription factors. Reviews in Medical Virology. 9: 31-8. PMID 10371670 DOI: 10.1002/(Sici)1099-1654(199901/03)9:1<31::Aid-Rmv231>3.0.Co;2-2  0.368
1999 Brownlees J, Gough G, Thomas S, Watts P, Cohen J, Coffin R, Latchman DS. Distinct responses of the herpes simplex virus and varicella zoster virus immediate early promoters to the cellular transcription factors Brn-3a and Brn-3b. The International Journal of Biochemistry & Cell Biology. 31: 451-61. PMID 10224669 DOI: 10.1016/S1357-2725(98)00151-4  0.361
1999 Liu YZ, Boxer LM, Latchman DS. Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade. Nucleic Acids Research. 27: 2086-90. PMID 10219080 DOI: 10.1093/Nar/27.10.2086  0.341
1999 Brar BK, Stephanou A, Wagstaff MJ, Coffin RS, Marber MS, Engelmann G, Latchman DS. Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress. Journal of Molecular and Cellular Cardiology. 31: 135-46. PMID 10072722 DOI: 10.1006/Jmcc.1998.0857  0.371
1999 Wagstaff MJ, Collaço-Moraes Y, Smith J, de Belleroche JS, Coffin RS, Latchman DS. Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector. The Journal of Biological Chemistry. 274: 5061-9. PMID 9988753 DOI: 10.1074/Jbc.274.8.5061  0.373
1999 Stephanou A, Isenberg DA, Nakajima K, Latchman DS. Signal transducer and activator of transcription-1 and heat shock factor-1 interact and activate the transcription of the Hsp-70 and Hsp-90beta gene promoters. The Journal of Biological Chemistry. 274: 1723-8. PMID 9880553 DOI: 10.1074/Jbc.274.3.1723  0.37
1999 Gay RD, Dawson SJ, Murphy WJ, Russell SW, Latchman DS. Activation of the iNOS gene promoter by Brn-3 POU family transcription factors is dependent upon the octamer motif in the promoter. Biochimica Et Biophysica Acta. 1443: 315-22. PMID 9878805 DOI: 10.1016/S0167-4781(98)00234-6  0.373
1999 Chapman CM, Latchman DS. The different alternatively spliced isoforms of the Oct-2 transcription factor repress the involucrin promoter in a cell type-specific manner. Molecular Biology Reports. 25: 253-7. PMID 9870616 DOI: 10.1023/A:1006801002594  0.379
1998 Wagstaff MJ, Lilley CE, Smith J, Robinson MJ, Coffin RS, Latchman DS. Gene transfer using a disabled herpes virus vector containing the EMCV IRES allows multiple gene expression in vitro and in vivo. Gene Therapy. 5: 1566-70. PMID 9930311 DOI: 10.1038/Sj.Gt.3300754  0.345
1998 Latchman DS. The Brn-3a transcription factor. The International Journal of Biochemistry & Cell Biology. 30: 1153-7. PMID 9839440 DOI: 10.1016/S1357-2725(98)00090-9  0.386
1998 Wagstaff MJ, Smith J, Collaco-Moraes Y, de Belleroche JS, Voellmy R, Coffin RS, Latchman DS. Delivery of a constitutively active form of the heat shock factor using a virus vector protects neuronal cells from thermal or ischaemic stress but not from apoptosis. The European Journal of Neuroscience. 10: 3343-50. PMID 9824447 DOI: 10.1046/J.1460-9568.1998.00339.X  0.379
1998 McMenamin MM, Byrnes AP, Pike FG, Charlton HM, Coffin RS, Latchman DS, Wood MJA. Potential and limitations of a γ34.5 mutant of herpes simplex 1 as a gene therapy vector in the CNS Gene Therapy. 5: 594-604. PMID 9797863 DOI: 10.1038/Sj.Gt.3300639  0.336
1998 Zhao J, Renner O, Wightman L, Sugden PH, Stewart L, Miller AD, Latchman DS, Marber MS. The expression of constitutively active isotypes of protein kinase C to investigate preconditioning. The Journal of Biological Chemistry. 273: 23072-9. PMID 9722533 DOI: 10.1074/Jbc.273.36.23072  0.309
1998 Dawson SJ, Palmer RD, Morris PJ, Latchman DS. Functional role of position 22 in the homeodomain of Brn-3 transcription factors. Neuroreport. 9: 2305-9. PMID 9694219 DOI: 10.1097/00001756-199807130-00029  0.38
1998 Stephanou A, Conroy S, Isenberg DA, Maione D, Poli V, Ciliberto G, Latchman DS. Elevation of IL-6 in transgenic mice results in increased levels of the 90 kDa heat shock protein (hsp90) and the production of anti-hsp90 antibodies. Journal of Autoimmunity. 11: 249-53. PMID 9693973 DOI: 10.1006/Jaut.1998.0194  0.302
1998 Patel Y, Gough G, Coffin RS, Thomas S, Cohen JI, Latchman DS. Cell type specific repression of the varicella zoster virus immediate early gene 62 promoter by the cellular Oct-2 transcription factor. Biochimica Et Biophysica Acta. 1397: 268-74. PMID 9582435 DOI: 10.1016/S0167-4781(97)00216-9  0.392
1998 Wyatt S, Ensor L, Begbie J, Ernfors P, Reichardt LF, Latchman DS. NT-3 regulates expression of Brn3a but not Brn3b in developing mouse trigeminal sensory neurons. Brain Research. Molecular Brain Research. 55: 254-64. PMID 9582431 DOI: 10.1016/S0169-328X(98)00006-0  0.329
1998 Smith MD, Morris PJ, Latchman DS. The Brn-3c transcription factor contains a neuronal-specific activation domain. Neuroreport. 9: 851-6. PMID 9579678 DOI: 10.1097/00001756-199803300-00016  0.383
1998 Budhram-Mahadeo V, Parker M, Latchman DS. POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element. Molecular and Cellular Biology. 18: 1029-41. PMID 9448000 DOI: 10.1128/Mcb.18.2.1029  0.336
1998 Latchman DS. How can we use our growing understanding of gene transcription to discover effective new medicines? Current Opinion in Biotechnology. 8: 713-7. PMID 9425662 DOI: 10.1016/S0958-1669(97)80125-5  0.336
1998 Thomas S, Coffin RS, Watts P, Gough G, Latchman DS. The TAATGARAT Motif in the Herpes Simplex Virus Immediate-Early Gene Promoters Can Confer both Positive and Negative Responses to Cellular Octamer-Binding Proteins When It Is Located within the Viral Genome Journal of Virology. 72: 3495-3500. DOI: 10.1128/Jvi.72.4.3495-3500.1998  0.348
1997 Deans ZC, Dawson SJ, Kilimann MW, Wallace D, Wilson MC, Latchman DS. Differential regulation of genes encoding synaptic proteins by the Oct-2 transcription factor. Brain Research. Molecular Brain Research. 51: 1-7. PMID 9427500 DOI: 10.1016/S0169-328X(97)00204-0  0.396
1997 Howard MK, Coffin RS, Maclean AR, Brown SM, Bailey D, Anderson PN, Burnstock G, Latchman DS. Gene delivery to rat enteric neurons using herpes simplex virus-based vectors. Journal of Molecular Neuroscience : Mn. 9: 65-74. PMID 9407388 DOI: 10.1007/Bf02736851  0.318
1997 Gay RD, Dawson SJ, Latchman DS. The different inhibitory domains of the Oct-2 transcription factor have distinct functional activities. Febs Letters. 416: 135-8. PMID 9369198 DOI: 10.1016/S0014-5793(97)01184-8  0.327
1997 Morris PJ, Dawson SJ, Wilson MC, Latchman DS. A single residue within the homeodomain of the Brn-3 POU family transcription factors determines whether they activate or repress the SNAP-25 promoter. Neuroreport. 8: 2041-5. PMID 9223099 DOI: 10.1097/00001756-199705260-00047  0.365
1997 Rose LM, Latchman DS, Isenberg DA. Apoptosis in peripheral lymphocytes in systemic lupus erythematosus: A review British Journal of Rheumatology. 36: 158-163. PMID 9133921 DOI: 10.1093/Rheumatology/36.2.158  0.314
1997 Stephanou A, Amin V, Isenberg DA, Akira S, Kishimoto T, Latchman DS. Interleukin 6 activates heat-shock protein 90 beta gene expression. The Biochemical Journal. 103-6. PMID 9003407 DOI: 10.1042/Bj3210103  0.303
1997 Smith MD, Dawson SJ, Latchman DS. Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor. The Journal of Biological Chemistry. 272: 1382-8. PMID 8995448 DOI: 10.1074/Jbc.272.2.1382  0.386
1997 Smith MD, Dawson SJ, Latchman DS. The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins. Molecular and Cellular Biology. 17: 345-54. PMID 8972215 DOI: 10.1128/Mcb.17.1.345  0.384
1997 Latchman DS. Inhibitory transcription factors. The International Journal of Biochemistry & Cell Biology. 28: 965-74. PMID 8930119 DOI: 10.1016/1357-2725(96)00039-8  0.333
1997 Kendall G, Crankson H, Ensor E, Lublin DM, Latchman DS. Activation of the gene encoding decay accelerating factor following nerve growth factor treatment of sensory neurons is mediated by promoter sequences within 206 bases of the transcriptional start site. Journal of Neuroscience Research. 45: 96-103. PMID 8843027 DOI: 10.1002/(Sici)1097-4547(19960715)45:2<96::Aid-Jnr2>3.0.Co;2-A  0.343
1997 Latchman DS. Activation and repression of gene expression by POU family transcription factors. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 351: 511-5. PMID 8735273 DOI: 10.1098/Rstb.1996.0049  0.376
1996 Morris PJ, Lakin ND, Dawson SJ, Ryabinin AE, Kilimann MW, Wilson MC, Latchman DS. Differential regulation of genes encoding synaptic proteins by members of the Brn-3 subfamily of POU transcription factors. Brain Research. Molecular Brain Research. 43: 279-85. PMID 9037543 DOI: 10.1016/S0169-328X(96)00207-0  0.382
1996 Wagstaff MJ, Collaço-Moraes Y, Aspey BS, Coffin RS, Harrison MJ, Latchman DS, de Belleroche JS. Focal cerebral ischaemia increases the levels of several classes of heat shock proteins and their corresponding mRNAs. Brain Research. Molecular Brain Research. 42: 236-44. PMID 9013779 DOI: 10.1016/S0169-328X(96)00127-1  0.303
1996 Watson A, Latchman D. Gene Delivery into Neuronal Cells by Calcium Phosphate-Mediated Transfection Methods. 10: 289-291. PMID 8954840 DOI: 10.1006/Meth.1996.0105  0.328
1996 Deans Z, Dawson SJ, Xie J, Young AP, Wallace D, Latchman DS. Differential regulation of the two neuronal nitric-oxide synthase gene promoters by the Oct-2 transcription factor. The Journal of Biological Chemistry. 271: 32153-8. PMID 8943269 DOI: 10.1074/Jbc.271.50.32153  0.4
1996 Latchman DS. The Oct-2 transcription factor. The International Journal of Biochemistry & Cell Biology. 28: 1081-3. PMID 8930131 DOI: 10.1016/1357-2725(96)00050-7  0.414
1996 Ensor E, Kendall G, Allchorne A, Woolf CJ, Latchman DS. Induction of the Oct-2 transcription factor in primary sensory neurons during inflammation is nerve growth factor-dependent. Neuroscience Letters. 204: 29-32. PMID 8929970 DOI: 10.1016/0304-3940(96)12308-9  0.323
1996 Amin V, Cumming DV, Latchman DS. Over-expression of heat shock protein 70 protects neuronal cells against both thermal and ischaemic stress but with different efficiencies. Neuroscience Letters. 206: 45-8. PMID 8848278 DOI: 10.1016/0304-3940(96)12421-6  0.33
1996 Liu YZ, Dawson SJ, Latchman DS. Alternative splicing of the Brn-3a and Brn-3b transcription factor RNAs is regulated in neuronal cells. Journal of Molecular Neuroscience : Mn. 7: 77-85. PMID 8835784 DOI: 10.1007/Bf02736850  0.392
1996 Galea-Lauri J, Latchman DS, Katz DR. The role of the 90-kDa heat shock protein in cell cycle control and differentiation of the monoblastoid cell line U937. Experimental Cell Research. 226: 243-54. PMID 8806428 DOI: 10.1006/Excr.1996.0225  0.344
1996 Wyatt S, Mailhos C, Latchman DS. Trigeminal ganglion neurons are protected by the heat shock proteins hsp70 and hsp90 from thermal stress but not from programmed cell death following nerve growth factor withdrawal Molecular Brain Research. 39: 52-56. PMID 8804713 DOI: 10.1016/0169-328X(95)00352-S  0.341
1996 Smith MD, Latchman DS. The functionally antagonistic POU family transcription factors Brn-3a and Brn-3b show opposite changes in expression during the growth arrest and differentiation of human neuroblastoma cells. International Journal of Cancer. 67: 653-60. PMID 8782654 DOI: 10.1002/(Sici)1097-0215(19960904)67:5<653::Aid-Ijc11>3.0.Co;2-6  0.361
1996 Begbie JL, Wood JN, Anderson PN, Latchman DS. Specific up-regulation of the POU domain transcription factor Oct-2 following axotomy. Neuroscience Letters. 207: 183-6. PMID 8728480 DOI: 10.1016/0304-3940(96)12514-3  0.359
1996 Milton NG, Bessis A, Changeux JP, Latchman DS. Differential regulation of neuronal nicotinic acetylcholine receptor subunit gene promoters by Brn-3 POU family transcription factors. The Biochemical Journal. 317: 419-23. PMID 8713067 DOI: 10.1042/Bj3170419  0.323
1996 Liu YZ, Dawson SJ, Gerster T, Friedl E, Pengue G, Matthias P, Lania L, Latchman DS. The ability of the inhibitory domain of the POU family transcription factor Oct-2 to interfere with promoter activation by different classes of activation domains is dependent upon the nature of the basal promoter elements. The Journal of Biological Chemistry. 271: 20853-60. PMID 8702841 DOI: 10.1074/Jbc.271.34.20853  0.306
1996 Deans Z, Dawson SJ, Buttery L, Polak JM, Wallace D, Latchman DS. Direct evidence that the POU family transcription factor Oct-2 represses the cellular tyrosine hydroxylase gene in neuronal cells. Journal of Molecular Neuroscience : Mn. 6: 159-67. PMID 8672399 DOI: 10.1007/Bf02736762  0.388
1996 Dawson SJ, Liu YZ, Rodel B, Möröy T, Latchman DS. The ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elements. The Biochemical Journal. 439-43. PMID 8670054 DOI: 10.1042/Bj3140439  0.363
1996 Dawson SJ, Morris PJ, Latchman DS. A single amino acid change converts an inhibitory transcription factor into an activator. The Journal of Biological Chemistry. 271: 11631-3. PMID 8662774 DOI: 10.1074/Jbc.271.20.11631  0.308
1996 Budhram-Mahadeo V, Morris PJ, Lakin ND, Dawson SJ, Latchman DS. The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site. The Journal of Biological Chemistry. 271: 9108-13. PMID 8621561 DOI: 10.1074/Jbc.271.15.9108  0.324
1996 Amin V, Cumming DV, Coffin RS, Latchman DS. The degree of protection provided to neuronal cells by a pre-conditioning stress correlates with the amount of heat shock protein 70 it induces and not with the similarity of the subsequent stress. Neuroscience Letters. 200: 85-8. PMID 8614569 DOI: 10.1016/0304-3940(95)12074-E  0.3
1996 Heads RJ, Latchman DS, Yellon DM. Differential stress protein mRNA expression during early ischaemic preconditioning in the rabbit heart and its relationship to adenosine receptor function. Journal of Molecular and Cellular Cardiology. 27: 2133-48. PMID 8576930 DOI: 10.1016/S0022-2828(95)91299-1  0.332
1996 Lillycrop KA, Latchman DS. The inhibitory domain in the Oct-2 transcription factor represses gene activity in a cell type-specific and promoter-independent manner. Molecular Biology Reports. 21: 87-94. PMID 8531926 DOI: 10.1007/Bf00986498  0.341
1996 Heads RJ, Yellon DM, Latchman DS. Differential cytoprotection against heat stress or hypoxia following expression of specific stress protein genes in myogenic cells. Journal of Molecular and Cellular Cardiology. 27: 1669-78. PMID 8523429 DOI: 10.1016/S0022-2828(95)90722-X  0.335
1996 Latchman DS. Transcription-factor mutations and disease. The New England Journal of Medicine. 334: 28-33. PMID 7494569 DOI: 10.1056/Nejm199601043340108  0.354
1995 Ryabinin AE, Sato TN, Morris PJ, Latchman DS, Wilson MC. Immediate upstream promoter regions required for neurospecific expression of SNAP-25. Journal of Molecular Neuroscience : Mn. 6: 201-10. PMID 8672402 DOI: 10.1007/Bf02736765  0.35
1995 Kendall G, Ensor E, Brar-Rai A, Winter J, Latchman DS. Nerve growth factor induces expression of immediate-early genes NGFI-A (Egr-1) and NGFI-B (nur 77) in adult rat dorsal root ganglion neurons. Brain Research. Molecular Brain Research. 25: 73-9. PMID 7984055 DOI: 10.1016/0169-328X(94)90280-1  0.346
1995 Latchman DS. Herpes simplex virus vectors for gene therapy. Molecular Biotechnology. 2: 179-95. PMID 7866875 DOI: 10.1007/Bf02824809  0.301
1995 Budhram-Mahadeo V, Morris PJ, Lakin ND, Theil T, Ching GY, Lillycrop KA, Möröy T, Liem RK, Latchman DS. Activation of the alpha-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein. The Journal of Biological Chemistry. 270: 2853-8. PMID 7852360 DOI: 10.1074/Jbc.270.6.2853  0.348
1995 Lakin ND, Morris PJ, Theil T, Sato TN, Möröy T, Wilson MC, Latchman DS. Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor. The Journal of Biological Chemistry. 270: 15858-63. PMID 7797590 DOI: 10.1074/Jbc.270.26.15858  0.4
1995 Milton NG, Bessis A, Changeux JP, Latchman DS. The neuronal nicotinic acetylcholine receptor alpha 2 subunit gene promoter is activated by the Brn-3b POU family transcription factor and not by Brn-3a or Brn-3c. The Journal of Biological Chemistry. 270: 15143-7. PMID 7797498 DOI: 10.1074/Jbc.270.25.15143  0.343
1995 Rose LM, Latchman DS, Isenberg DA. Bcl-2 expression is unaltered in unfractionated peripheral blood mononuclear cells in patients with systemic lupus erythematosus Rheumatology. 34: 316-320. PMID 7788144 DOI: 10.1093/Rheumatology/34.4.316  0.313
1995 Coffin RS, Howard MK, Latchman DS. Altered dinucleotide content within the latently transcribed regions of the DNA of alpha herpes viruses - Implications for latent RNA expression and DNA structure Virology. 209: 358-365. PMID 7778270 DOI: 10.1006/Viro.1995.1267  0.314
1995 Watson A, Ensor E, Symes A, Winter J, Kendall G, Latchman D. A minimal CGRP gene promoter is inducible by nerve growth factor in adult rat dorsal root ganglion neurons but not in PC12 phaeochromocytoma cells European Journal of Neuroscience. 7: 394-400. PMID 7773437 DOI: 10.1111/J.1460-9568.1995.Tb00335.X  0.364
1995 Huntriss JD, Twomey BM, Isenberg DA, Latchman DS. Enhanced transcription of the gene encoding the SmN autoantigen in patients with systemic lupus erythematosus does not result in enhanced levels of the SmN protein. Autoimmunity. 19: 81-7. PMID 7772706 DOI: 10.3109/08916939409009535  0.373
1995 Liu YZ, Lillycrop KA, Latchman DS. Regulated splicing of the Oct-2 transcription factor RNA in neuronal cells. Neuroscience Letters. 183: 8-12. PMID 7746493 DOI: 10.1016/0304-3940(94)11102-O  0.381
1995 Kendall G, Brar-Rai A, Ensor E, Winter J, Wood JN, Latchman DS. Nerve growth factor induces the Oct-2 transcription factor in sensory neurons with the kinetics of an immediate-early gene. Journal of Neuroscience Research. 40: 169-76. PMID 7745610 DOI: 10.1002/Jnr.490400205  0.355
1995 Lillycrop KA, Liu YZ, Theil T, Möröy T, Latchman DS. Activation of the herpes simplex virus immediate-early gene promoters by neuronally expressed POU family transcription factors. The Biochemical Journal. 581-4. PMID 7733899 DOI: 10.1042/Bj3070581  0.391
1995 Budhram-Mahadeo V, Lillycrop KA, Latchman DS. The levels of the antagonistic POU family transcription factors Brn-3a and Brn-3b in neuronal cells are regulated in opposite directions by serum growth factors. Neuroscience Letters. 185: 48-51. PMID 7731552 DOI: 10.1016/0304-3940(94)11222-5  0.366
1995 Watson A, Latchman D. The cyclic AMP response element in the calcitonin/calcitonin gene-related peptide gene promoter is necessary but not sufficient for its activation by nerve growth factor. The Journal of Biological Chemistry. 270: 9655-60. PMID 7721899 DOI: 10.1074/Jbc.270.16.9655  0.318
1995 Lakin ND, Palmer R, Lillycrop KA, Howard MK, Burke LC, Thomas NSB, Latchman DS. Down regulation of the octamer binding protein Oct-1 during growth arrest and differentiation of a neuronal cell line Molecular Brain Research. 28: 47-54. PMID 7707877 DOI: 10.1016/0169-328X(94)00183-F  0.363
1995 Latchman DS, Isenberg DA. The role of hsp90 in SLE. Autoimmunity. 19: 211-8. PMID 7605872 DOI: 10.3109/08916939408995696  0.314
1994 Twomey BM, Amin V, Isenberg DA, Latchman DS. Elevated levels of the 70 kD heat shock protein in patients with systemic lupus erythematosus are not dependent on enhanced transcription of the hsp70 gene. Lupus. 2: 297-301. PMID 8305922 DOI: 10.1177/096120339300200504  0.34
1994 Lillycrop KA, Howard MK, Estridge JK, Latchman DS. Inhibition of herpes simplex virus infection by ectopic expression of neuronal splice variants of the Oct-2 transcription factor Nucleic Acids Research. 22: 815-820. PMID 8139923 DOI: 10.1093/Nar/22.5.815  0.354
1994 Lillycrop KA, Estridge JK, Latchman DS. Functional interaction between different isoforms of the Oct-2 transcription factor expressed in neuronal cells. The Biochemical Journal. 245-8. PMID 8129727 DOI: 10.1042/Bj2980245  0.379
1994 Mailhos C, Howard MK, Latchman DS. A common pathway mediates retinoic acid and PMA-dependent programmed cell death (apoptosis) of neuronal cells Brain Research. 644: 7-12. PMID 8032951 DOI: 10.1016/0006-8993(94)90339-5  0.305
1994 Budhram-Mahadeo V, Lillycrop KA, Latchman DS. Cell cycle arrest and morphological differentiation can occur in the absence of apoptosis in a neuronal cell line. Neuroscience Letters. 165: 18-22. PMID 8015721 DOI: 10.1016/0304-3940(94)90699-8  0.336
1994 Lillycrop KA, Dawson SJ, Estridge JK, Gerster T, Matthias P, Latchman DS. Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependent on an inhibitory region at the N terminus of the protein. Molecular and Cellular Biology. 14: 7633-42. PMID 7935477 DOI: 10.1128/Mcb.14.11.7633  0.357
1994 Morris PJ, Theil T, Ring CJ, Lillycrop KA, Moroy T, Latchman DS. The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain. Molecular and Cellular Biology. 14: 6907-14. PMID 7935408 DOI: 10.1128/Mcb.14.10.6907  0.329
1994 Mailhos C, Howard MK, Latchman DS. Heat shock proteins hsp90 and hsp70 protect neuronal cells from thermal stress but not from programmed cell death Journal of Neurochemistry. 63: 1787-1795. PMID 7931334 DOI: 10.1046/J.1471-4159.1994.63051787.X  0.337
1994 Conroy SE, Faulds GB, Williams W, Latchman DS, Isenberg DA. Detection of autoantibodies to the 90 kDa heat shock protein in systemic lupus erythematosus and other autoimmune diseases. British Journal of Rheumatology. 33: 923-6. PMID 7921751 DOI: 10.1093/Rheumatology/33.10.923  0.305
1994 Dawson SJ, Yoon SO, Chikaraishi DM, Lillycrop KA, Latchman DS. The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter. Nucleic Acids Research. 22: 1023-8. PMID 7908738 DOI: 10.1093/Nar/22.6.1023  0.386
1994 Huntriss JD, Barr JA, Horn DA, Williams DG, Latchman DS. Mice lacking Snrpn expression show normal regulation of neuronal alternative splicing events. Molecular Biology Reports. 20: 19-25. PMID 7845394 DOI: 10.1007/Bf00999851  0.336
1994 Rose LM, Latchman DS, Isenberg DA. Bcl-2 and fas, molecules which influence apoptosis. A possible role in systemic lupus erythematosus? Autoimmunity. 17: 271-278. PMID 7524704 DOI: 10.3109/08916939409010667  0.327
1993 Gerrelli D, Grimaldi K, Horn D, Mahadeva U, Sharpe N, Latchman DS. The cardiac form of the tissue-specific SmN protein is identical to the brain and embryonic forms of the protein. Journal of Molecular and Cellular Cardiology. 25: 321-9. PMID 8510173 DOI: 10.1006/Jmcc.1993.1038  0.349
1993 Horn DA, Latchman DS. A distal region of the CALC-1 gene is necessary for regulated alternative splicing. Febs Letters. 324: 123-6. PMID 8508914 DOI: 10.1016/0014-5793(93)81376-B  0.33
1993 Mailhos C, Howard MK, Latchman DS. Heat shock protects neuronal cells from programmed cell death by apoptosis Neuroscience. 55: 621-627. PMID 8413925 DOI: 10.1016/0306-4522(93)90428-I  0.339
1993 Horn DA, Latchman DS. The tissue specific SmN protein does not influence the alternative splicing of endogenous N-Cam and C-SRC RNAs in transfected 3T3 cells. Brain Research. Molecular Brain Research. 19: 181-7. PMID 8412559 DOI: 10.1016/0169-328X(93)90024-J  0.317
1993 Dhillon V, McCallum S, Wilks D, Twomey B, Latchman D, Isenberg D. The differential expression of heat shock proteins in rheumatic disease. British Journal of Rheumatology. 32: 883-92. PMID 8401997 DOI: 10.1093/Rheumatology/32.10.883  0.314
1993 Lillycrop KA, Estridge JK, Latchman DS. The octamer binding protein Oct-2 inhibits transactivation of the herpes simplex virus immediate-early genes by the virion protein Vmw65. Virology. 196: 888-91. PMID 8396817 DOI: 10.1006/Viro.1993.1552  0.396
1993 Howard MK, Burke LC, Mailhos C, Pizzey A, Gilbert CS, Lawson WD, Collins MKL, Thomas NSB, Latchman DS. Cell cycle arrest of proliferating neuronal cells by serum deprivation can result in either apoptosis or differentiation Journal of Neurochemistry. 60: 1783-1791. PMID 8386223 DOI: 10.1111/J.1471-4159.1993.Tb13404.X  0.326
1993 Huntriss JD, Latchman DS, Williams DG. The snRNP core protein SmB and tissue-specific SmN protein are differentially distributed between snRNP particles. Nucleic Acids Research. 21: 4047-53. PMID 8371979 DOI: 10.1093/Nar/21.17.4047  0.318
1993 Horn DA, Latchman DS. Alternative splicing of the mRNA encoding the alpha subunits of the G(o) GTP-binding protein during brain development and in neuronal cell lines. Neuroscience Letters. 155: 57-60. PMID 8361664 DOI: 10.1016/0304-3940(93)90672-8  0.325
1993 Twomey BM, McCallum S, Isenberg DA, Latchman DS. Elevation of heat shock protein synthesis and hsp gene transcription during monocyte to macrophage differentiation of U937 cells. Clinical and Experimental Immunology. 93: 178-83. PMID 8348742 DOI: 10.1111/J.1365-2249.1993.Tb07962.X  0.348
1993 Ring CJ, Latchman DS. The human Brn-3b POU transcription factor shows only limited homology to the Brn-3a/RDC-1 factor outside the conserved POU domain. Nucleic Acids Research. 21: 2946. PMID 8332509 DOI: 10.1093/Nar/21.12.2946  0.312
1993 Morris PJ, Ring CJ, Lillycrop KA, Latchman DS. Transactivation of the human papilloma virus 16 octamer motif by the octamer binding protein Oct-2 requires both the N and C terminal activation domains. Nucleic Acids Research. 21: 4506-10. PMID 8233784 DOI: 10.1093/Nar/21.19.4506  0.342
1993 Twomey BM, Dhillon VB, McCallum S, Isenberg DA, Latchman DS. Elevated levels of the 90 kD heat shock protein in patients with systemic lupus erythematosus are dependent upon enhanced transcription of the hsp90 beta gene. Journal of Autoimmunity. 6: 495-506. PMID 8216691 DOI: 10.1006/Jaut.1993.1041  0.338
1993 Erkeller-Yüksel FM, Isenberg DA, Dhillon VB, Latchman DS, Lydyard PM. Surface expression of heat shock protein 90 by blood mononuclear cells from patients with systemic lupus erythematosus. Journal of Autoimmunity. 5: 803-14. PMID 1489490 DOI: 10.1016/0896-8411(92)90194-U  0.306
1993 Twomey B, McCallum S, Dhillon V, Isenberg D, Latchman D. Transcription of the genes encoding the small heat shock protein ubiquitin is unchanged in patients with systemic lupus erythematosus. Autoimmunity. 13: 197-200. PMID 1335295 DOI: 10.3109/08916939209004824  0.353
1992 Chapman CJ, Harris JD, Hardwicke MA, Sandri-Goldin RM, Collins MK, Latchman DS. Promoter-independent activation of heterologous virus gene expression by the herpes simplex virus immediate-early protein ICP27. Virology. 186: 573-8. PMID 1733102 DOI: 10.1016/0042-6822(92)90023-I  0.371
1992 Timmons PM, Brickell PM, Latchman DS, Rigby PW. Activation of endogenous retroviral transcription in SV40-transformed mouse cells. Nucleic Acids Research. 19: 7215-8. PMID 1662812 DOI: 10.1093/Nar/19.25.7215  0.328
1992 Grimaldi K, Gerrelli D, Sharpe NG, Lund T, Latchman DS. The intronless mouse gene for the tissue specific splicing protein SmN is a processed pseudogene containing a stop codon after thirty-one amino acids. Dna Sequence : the Journal of Dna Sequencing and Mapping. 2: 241-6. PMID 1627828 DOI: 10.3109/10425179209020809  0.335
1992 Orchard K, Lang G, Collins M, Latchman D. Characterization of a novel T lymphocyte protein which binds to a site related to steroid/thyroid hormone receptor response elements in the negative regulatory sequence of the human immunodeficiency virus long terminal repeat. Nucleic Acids Research. 20: 5429-34. PMID 1437560 DOI: 10.1093/Nar/20.20.5429  0.311
1992 Horn DA, Latchman DS. Neuronal expression of the tissue specific splicing protein SmN and its possible role in pre mRNA splicing. Biochemical Society Transactions. 20: 266S. PMID 1426556 DOI: 10.1042/Bst020266S  0.328
1992 Lillycrop KA, Budrahan VS, Lakin ND, Terrenghi G, Wood JN, Polak JM, Latchman DS. A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells. Nucleic Acids Research. 20: 5093-6. PMID 1383937 DOI: 10.1093/Nar/20.19.5093  0.391
1992 Wheatley SC, Dent CL, Wood JN, Latchman DS. Elevation of cyclic AMP levels in cell lines derived from latently infectable sensory neurons increases their permissivity for herpes virus infection by activating the viral immediate-early 1 gene promoter. Brain Research. Molecular Brain Research. 12: 149-54. PMID 1372062 DOI: 10.1016/0169-328X(92)90078-P  0.329
1992 Suburo AM, Wheatley SC, Horn DA, Gibson SJ, Jahn R, Fischer-Colbrie R, Wood JN, Latchman DS, Polak JM. Intracellular redistribution of neuropeptides and secretory proteins during differentiation of neuronal cell lines. Neuroscience. 46: 881-9. PMID 1347412 DOI: 10.1016/0306-4522(92)90191-4  0.332
1992 Horn DA, Suburo A, Terenghi G, Hudson LD, Polak JM, Latchman DS. Expression of the tissue specific splicing protein SmN in neuronal cell lines and in regions of the brain with different splicing capacities. Brain Research. Molecular Brain Research. 16: 13-9. PMID 1334191 DOI: 10.1016/0169-328X(92)90188-H  0.37
1991 Sharpe NG, Williams DG, Latchman DS. Regulated expression of the small nuclear ribonucleoprotein particle protein SmN in embryonic stem cell differentiation. Molecular and Cellular Biology. 10: 6817-20. PMID 2174118 DOI: 10.1128/Mcb.10.12.6817  0.328
1991 Dent CL, Lillycrop KA, Estridge JK, Thomas NS, Latchman DS. The B-cell and neuronal forms of the octamer-binding protein Oct-2 differ in DNA-binding specificity and functional activity. Molecular and Cellular Biology. 11: 3925-30. PMID 2072899 DOI: 10.1128/Mcb.11.8.3925  0.398
1991 Lea I, Moore HD, Latchman DS. Differential expression of the mouse U1a and U1b SnRNA genes is not dependent on sequence differences in the octamer motif. The Biochemical Journal. 719-22. PMID 1872807 DOI: 10.1042/Bj2770719  0.365
1991 Wheatley SC, Dent CL, Wood JN, Latchman DS. A cellular factor binding to the TAATGARAT DNA sequence prevents the expression of the HSV immediate-early genes following infection of nonpermissive cell lines derived from dorsal root ganglion neurons. Experimental Cell Research. 194: 78-82. PMID 1849828 DOI: 10.1016/0014-4827(91)90132-E  0.383
1991 Jang Kl, Pulverer B, Woodgett JR, Latchman DS. Activation of the cellular transcription factor AP-1 in herpes simplex virus infected cells is dependent on the viral immediate-early protein ICPO Nucleic Acids Research. 19: 4879-4883. PMID 1656381 DOI: 10.1093/Nar/19.18.4879  0.363
1991 Lillycrop KA, Dent CL, Wheatley SC, Beech MN, Ninkina NN, Wood JN, Latchman DS. The octamer-binding protein Oct-2 represses HSV immediate-early genes in cell lines derived from latently infectable sensory neurons. Neuron. 7: 381-90. PMID 1654947 DOI: 10.1016/0896-6273(91)90290-G  0.386
1991 Bansal GS, Norton PM, Latchman DS. The 90-kDa heat shock protein protects mammalian cells from thermal stress but not from viral infection. Experimental Cell Research. 195: 303-6. PMID 1649055 DOI: 10.1016/0014-4827(91)90377-7  0.335
1990 Perkins ND, Orchard KH, Collins ML, Latchman DS, Goodwin GH. Detection in non-erythroid cells of a factor with the binding characteristics of the erythroid cell transcription factor EF1. The Biochemical Journal. 269: 543-5. PMID 2386492 DOI: 10.1042/Bj2690543  0.365
1990 Estridge JK, Kemp LM, Latchman DS. The herpes simplex virus protein Vmw65 can trans-activate both viral and cellular promoters in neuronal cells. The Biochemical Journal. 271: 273-6. PMID 2171502 DOI: 10.1042/Bj2710273  0.397
1990 Wheatley SC, Kemp LM, Wood JN, Latchman DS. Cell lines derived from dorsal root ganglion neurons are nonpermissive for HSV and express only the latency-associated transcript following infection. Experimental Cell Research. 190: 243-6. PMID 2170153 DOI: 10.1016/0014-4827(90)90192-D  0.346
1990 Zwaagstra JC, Ghiasi H, Slanina SM, Nesburn AB, Wheatley SC, Lillycrop K, Wood J, Latchman DS, Patel K, Wechsler SL. Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript. Journal of Virology. 64: 5019-28. PMID 2168984 DOI: 10.1128/Jvi.64.10.5019-5028.1990  0.353
1990 Dent CL, Estridge JK, Kemp LM, Latchman DS. Inhibition of histone H2B gene transcription and of cellular growth by a truncated viral trans-activator protein. Molecular and Cellular Biology. 10: 3258-61. PMID 2160597 DOI: 10.1128/Mcb.10.6.3258  0.389
1990 Kemp LM, Dent CL, Latchman DS. Octamer motif mediates transcriptional repression of HSV immediate-early genes and octamer-containing cellular promoters in neuronal cells. Neuron. 4: 215-22. PMID 2155008 DOI: 10.1016/0896-6273(90)90096-X  0.398
1990 Wood JN, Bevan SJ, Coote PR, Dunn PM, Harmar A, Hogan P, Latchman DS, Morrison C, Rougon G, Theveniau M. Novel cell lines display properties of nociceptive sensory neurons. Proceedings. Biological Sciences / the Royal Society. 241: 187-94. PMID 1979443 DOI: 10.1098/Rspb.1990.0084  0.337
1990 Orchard K, Perkins N, Chapman C, Harris J, Emery V, Goodwin G, Latchman D, Collins M. A novel T-cell protein which recognizes a palindromic sequence in the negative regulatory element of the human immunodeficiency virus long terminal repeat. Journal of Virology. 64: 3234-3239. DOI: 10.1128/Jvi.64.7.3234-3239.1990  0.316
1989 Davis JM, La Thangue NB, Taylor DL, Latchman DS, Anderson M, Tyms AS. Cellular polypeptides overexpressed after herpes simplex infection permit virus subtyping and may help diagnose cervical cancer. Genitourinary Medicine. 64: 321-6. PMID 2849592 DOI: 10.1136/Sti.64.5.321  0.324
1989 Sharpe NG, Williams DG, Norton P, Latchman DS. Expression of the SmB' splicing protein in rodent cells capable of following an alternative RNA splicing pathway. Febs Letters. 243: 132-6. PMID 2783916 DOI: 10.1016/0014-5793(89)80114-0  0.33
1989 Sharpe NG, Williams DG, Howarth DN, Coles B, Latchman DS. Isolation of cDNA clones encoding the human Sm B/B' auto-immune antigen and specifically reacting with human anti-Sm auto-immune sera. Febs Letters. 250: 585-90. PMID 2753153 DOI: 10.1016/0014-5793(89)80801-4  0.301
1989 Estridge JK, Kemp LM, La Thangue NB, Mann BS, Tyms AS, Latchman DS. The herpes simplex virus type 1 immediate-early protein ICP27 is obligately required for the accumulation of a cellular protein during viral infection. Virology. 168: 67-72. PMID 2535908 DOI: 10.1016/0042-6822(89)90404-2  0.327
1989 SHARPE NG, WILLIAMS DG, NORTON PM, LATCHMAN DS. Cell-type specific expression of the SmB' splicing protein and alternative RNA splicing Biochemical Society Transactions. 17: 357-358. DOI: 10.1042/Bst0170357  0.304
1988 La Thangue NB, Latchman DS. A cellular protein related to heat-shock protein 90 accumulates during herpes simplex virus infection and is overexpressed in transformed cells. Experimental Cell Research. 178: 169-79. PMID 2842174 DOI: 10.1016/0014-4827(88)90388-6  0.334
1988 Kemp LM, Latchman DS. Induction and repression of cellular gene transcription during herpes simplex virus infection are mediated by different viral immediate-early gene products. European Journal of Biochemistry. 174: 443-9. PMID 2838278 DOI: 10.1111/J.1432-1033.1988.Tb14118.X  0.346
1988 LaThangue NB, Latchman DS. Nuclear accumulation of a heat-shock 70-like protein during herpes simplex virus replication. Bioscience Reports. 7: 475-83. PMID 2827804 DOI: 10.1007/Bf01116504  0.322
1987 Latchman DS, Estridge JK, Kemp LM. Transcriptional induction of the ubiquitin gene during herpes simplex virus infection is dependent upon the viral immediate-early protein ICP4. Nucleic Acids Research. 15: 7283-93. PMID 2821506 DOI: 10.1093/Nar/15.18.7283  0.372
1987 Latchman DS, Chan WL, Leaver CE, Patel R, Oliver P, La Thangue NB. The human Mr 90,000 heat shock protein and the Escherichia coli Lon protein share an antigenic determinant. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 87: 961-7. PMID 2444389 DOI: 10.1016/0305-0491(87)90419-6  0.321
1986 Patel R, Chan WL, Kemp LM, La Thangue NB, Latchman DS. Isolation of cDNA clones derived from a cellular gene transcriptionally induced by herpes simplex virus. Nucleic Acids Research. 14: 5629-40. PMID 3016658 DOI: 10.1093/Nar/14.14.5629  0.358
1986 Kemp LM, Brickell PM, Thangue NBL, Latchman DS. Transcriptional induction of cellular gene expression during lytic infection with herpes simplex virus Bioscience Reports. 6: 945-951. PMID 2883998 DOI: 10.1007/Bf01114970  0.337
1985 Rigby PW, Brickell PM, Latchman DS, Murphy D, Westphal KH, Willison K. The activation of cellular genes in transformed cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 347-51. PMID 6151708 DOI: 10.1098/Rstb.1984.0138  0.33
1985 Brickell PM, Latchman DS, Murphy D, Willison K, Rigby PW. The class I major histocompatibility antigen gene activated in a line of SV40-transformed mouse cells is H-2Dd, not Qa/Tla. Nature. 316: 162-3. PMID 2989712 DOI: 10.1038/316162A0  0.304
1984 Murphy D, Brickell PM, Latchman DS, Willison K, Rigby PW. Transcripts regulated during normal embryonic development and oncogenic transformation share a repetitive element. Cell. 35: 865-71. PMID 6652687 DOI: 10.1016/0092-8674(83)90119-8  0.317
1984 Brickell PM, Latchman DS, Murphy D, Willison K, Rigby PW. Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse. Nature. 306: 756-60. PMID 6318117 DOI: 10.1038/306756A0  0.338
Low-probability matches (unlikely to be authored by this person)
2009 Sleiman PM, Healy DG, Muqit MM, Yang YX, Van Der Brug M, Holton JL, Revesz T, Quinn NP, Bhatia K, Diss JK, Lees AJ, Cookson MR, Latchman DS, Wood NW. Characterisation of a novel NR4A2 mutation in Parkinson's disease brain. Neuroscience Letters. 457: 75-9. PMID 19429166 DOI: 10.1016/J.Neulet.2009.03.021  0.3
1996 GRENFELL SJ, LATCHMAN DS, THOMAS NSB. CT-1 and Oct-2 DNA-binding site specificity is regulated in vitro by different kinases Biochemical Journal. 317: 959-959. DOI: 10.1042/Bj3170959C  0.3
2002 Storey N, Latchman D, Bevan S. Selective internalization of sodium channels in rat dorsal root ganglion neurons infected with herpes simplex virus-1. The Journal of Cell Biology. 158: 1251-62. PMID 12356869 DOI: 10.1083/Jcb.200204010  0.299
2008 Barry SP, Jayasinghe SN, Pericleous C, Hubank M, Latchman DS, Stephanou A. Gene expression studies on bio-electrosprayed primary cardiac myocytes Biotechnology Journal. 3: 530-535. PMID 18293311 DOI: 10.1002/Biot.200700266  0.299
2007 Wagstaff MJ, Shah M, McGrouther DA, Latchman DS. The heat shock proteins and plastic surgery. Journal of Plastic, Reconstructive & Aesthetic Surgery : Jpras. 60: 974-82. PMID 17662462 DOI: 10.1016/J.Bjps.2006.03.065  0.298
2001 Scarabelli T, Stephanou A, Rayment N, Pasini E, Comini L, Curello S, Ferrari R, Knight R, Latchman D. Apoptosis of Endothelial Cells Precedes Myocyte Cell Apoptosis in Ischemia/Reperfusion Injury Circulation. 104: 253-256. PMID 11457740 DOI: 10.1161/01.Cir.104.3.253  0.298
2001 Kumar S, Kalsi J, Ravirajan CT, Rahman A, Athwal D, Latchman DS, Isenberg DA, Pearl LH. Molecular cloning and expression of the Fabs of human autoantibodies in Escherichia coli. Determination of the heavy or light chain contribution to the anti-DNA/-cardiolipin activity of the Fab. The Journal of Biological Chemistry. 275: 35129-36. PMID 10893224 DOI: 10.1074/Jbc.M001976200  0.298
1995 Kalsi J, Ravirajan C, Wiloch-Winska H, Blanco F, Longhurst C, Williams W, Chapman C, Hillson J, Youniou P, Latchman D, Isenberg D. Analysis of three new idiotypes on human monoclonal autoantibodies. Lupus. 4: 375-389. PMID 8563732 DOI: 10.1177/096120339500400508  0.297
1999 Rahman MA, Kettleborough CA, Latchman DS, Isenberg DA. Properties of whole human IgG molecules produced by the expression of cloned anti-DNA antibody cDNA in mammalian cells. Journal of Autoimmunity. 11: 661-9. PMID 9878088 DOI: 10.1006/Jaut.1998.0241  0.297
1992 Latchman DS, Dent CL, Lillycrop KA, Wood JN. POU family transcription factors in sensory neurons. Biochemical Society Transactions. 20: 627-31. PMID 1426602 DOI: 10.1042/Bst0200627  0.297
1999 Rahman A, Latchman DS, Isenberg DA. The role of in vitro expression systems in the investigation of antibodies to DNA. Seminars in Arthritis and Rheumatism. 28: 130-9. PMID 9806374 DOI: 10.1016/S0049-0172(98)80046-2  0.297
1993 Moore A, Penfold LM, Johnson JL, Latchman DS, Moore HD. Human sperm-egg binding is inhibited by peptides corresponding to core region of an acrosomal serine protease inhibitor. Molecular Reproduction and Development. 34: 280-91. PMID 8471250 DOI: 10.1002/Mrd.1080340308  0.296
2006 Gandhi S, Muqit MM, Stanyer L, Healy DG, Abou-Sleiman PM, Hargreaves I, Heales S, Ganguly M, Parsons L, Lees AJ, Latchman DS, Holton JL, Wood NW, Revesz T. PINK1 protein in normal human brain and Parkinson's disease. Brain : a Journal of Neurology. 129: 1720-31. PMID 16702191 DOI: 10.1093/Brain/Awl114  0.296
1997 Rose LM, Latchman DS, Isenberg DA. Elevated soluble fas production in SLE correlates with HLA status not with disease activity Lupus. 6: 717-722. PMID 9412987 DOI: 10.1177/096120339700600907  0.296
2014 Ripoll VM, Lambrianides A, Pierangeli SS, Poulton K, Ioannou Y, Heywood WE, Mills K, Latchman DS, Isenberg DA, Rahman A, Giles IP. Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. Blood. 124: 3808-16. PMID 25301710 DOI: 10.1182/Blood-2014-05-577569  0.296
2008 Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Abramov AS, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, Downward J, Mansfield L, Jat P, Taylor J, ... ... Latchman D, et al. PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. Plos One. 3: e2455. PMID 18560593 DOI: 10.1371/Journal.Pone.0002455  0.296
1999 Latchman DS. Cardiotrophin-1 (CT-1): a novel hypertrophic and cardioprotective agent. International Journal of Experimental Pathology. 80: 189-96. PMID 10583628 DOI: 10.1046/J.1365-2613.1999.00114.X  0.295
1988 Latchman DS. A potential role for U1 RNA genes in gene duplication and conversion events. Febs Letters. 236: 5-8. PMID 3402617 DOI: 10.1016/0014-5793(88)80274-6  0.295
2004 Stephanou A, Chen-Scarabelli C, Latchman D, Gardin J, Narula J, Scarabelli T. 1041-98 Epigallocatechin-3-gallate inhibits stat-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis Journal of the American College of Cardiology. 43. DOI: 10.1016/S0735-1097(04)91090-X  0.294
1989 Norton PM, Isenberg DA, Latchman DS. Elevated levels of the 90 kd heat shock protein in a proportion of SLE patients with active disease. Journal of Autoimmunity. 2: 187-95. PMID 2765096 DOI: 10.1016/0896-8411(89)90154-6  0.294
2006 Yang YX, Muqit MMK, Latchman DS. Induction of parkin expression in the presence of oxidative stress European Journal of Neuroscience. 24: 1366-1372. PMID 16987221 DOI: 10.1111/J.1460-9568.2006.04998.X  0.293
2004 Scarabelli TM, Pasini E, Ferrari G, Ferrari M, Stephanou A, Lawrence K, Townsend P, Chen-Scarabelli C, Gitti G, Saravolatz L, Latchman D, Knight RA, Gardin JM. Warm blood cardioplegic arrest induces mitochondrial-mediated cardiomyocyte apoptosis associated with increased urocortin expression in viable cells. The Journal of Thoracic and Cardiovascular Surgery. 128: 364-71. PMID 15354093 DOI: 10.1016/J.Jtcvs.2003.11.028  0.293
2002 Rahman A, Haley J, Latchman DS. Molecular expression systems for anti-DNA antibodies--1. Lupus. 11: 824-32. PMID 12529047 DOI: 10.1191/0961203302Lu303Oa  0.292
2004 Kumar S, Kalsi J, Bunting K, Ravirajan CT, Latchman DS, Pearl LH, Isenberg DA. Fine binding characteristics of human autoantibodies-partial molecular characterization. Molecular Immunology. 41: 495-510. PMID 15183928 DOI: 10.1016/J.Molimm.2004.03.039  0.292
2005 Fraser SP, Diss JK, Chioni AM, Mycielska ME, Pan H, Yamaci RF, Pani F, Siwy Z, Krasowska M, Grzywna Z, Brackenbury WJ, Theodorou D, Koyutürk M, Kaya H, Battaloglu E, ... ... Latchman DS, et al. Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 5381-9. PMID 16061851 DOI: 10.1158/1078-0432.Ccr-05-0327  0.292
2001 Kumar S, Kalsi J, Latchman DS, Pearl LH, Isenberg DA. Expression of the Fabs of human auto-antibodies in Escherichia coli: optimization and determination of their fine binding characteristics and cross-reactivity. Journal of Molecular Biology. 308: 527-39. PMID 11327785 DOI: 10.1006/Jmbi.2001.4534  0.291
1999 Latchman DS. POU family transcription factors in the nervous system. Journal of Cellular Physiology. 179: 126-33. PMID 10199551 DOI: 10.1002/(Sici)1097-4652(199905)179:2<126::Aid-Jcp2>3.0.Co;2-M  0.291
2001 Ripley BJM, Isenberg DA, Latchman DS. Elevated levels of the 90 kDa heat shock protein (hsp90) in SLE correlate with levels of IL-6 and autoantibodies to hsp90 Journal of Autoimmunity. 17: 341-346. PMID 11771959 DOI: 10.1006/Jaut.2001.0549  0.291
2011 Pericleous C, Miles J, Esposito D, Garza-Garcia A, Driscoll PC, Lambrianides A, Latchman D, Isenberg D, Rahman A, Ioannou Y, Giles I. Evaluating the conformation of recombinant domain I of β(2)-glycoprotein I and its interaction with human monoclonal antibodies. Molecular Immunology. 49: 56-63. PMID 21899894 DOI: 10.1016/J.Molimm.2011.07.024  0.29
2006 Ndisang D, Faulkes DJ, Gascoyne D, Lee SA, Ripley BJ, Sindos M, Singer A, Budhram-Mahadeo V, Cason J, Latchman DS. Differential regulation of different human papilloma virus variants by the POU family transcription factor Brn-3a. Oncogene. 25: 51-60. PMID 16247485 DOI: 10.1038/Sj.Onc.1209006  0.29
2001 Rahman A, Haley J, Radway-Bright E, Nagl S, Low DG, Latchman DS, Isenberg DA. The importance of somatic mutations in the V(lambda) gene 2a2 in human monoclonal anti-DNA antibodies. Journal of Molecular Biology. 307: 149-60. PMID 11243810 DOI: 10.1006/Jmbi.2000.4491  0.29
1993 Dhillon V, Latchman D, Isenberg D. Heat shock proteins and systemic lupus erythematosus. Lupus. 1: 3-8. PMID 1845360 DOI: 10.1177/096120339100100102  0.289
1992 Wheatley SC, Suburo AM, Horn DA, Vucicevic V, Terenghi G, Polak JM, Latchman DS. Redistribution of secretory granule components precedes that of synaptic vesicle proteins during differentiation of a neuronal cell line in serum-free medium. Neuroscience. 51: 575-82. PMID 1336820 DOI: 10.1016/0306-4522(92)90297-F  0.289
1997 Rahman A, Menon S, Latchman DS, Isenberg DA. Sequences of monoclonal antiphospholipid antibodies: variations on an anti-DNA antibody theme. Seminars in Arthritis and Rheumatism. 26: 515-25. PMID 8916296 DOI: 10.1016/S0049-0172(96)80040-0  0.289
2002 Railson JE, Liao Z, Brar BK, Buddle JC, Pennica D, Stephanou A, Latchman DS. Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes Cytokine. 17: 243-253. PMID 12027405 DOI: 10.1006/Cyto.2001.1011  0.289
1997 Begbie JL, Latchman DS. The two activation domains of the Brn-3a transcription factor have distinct functional properties The International Journal of Biochemistry & Cell Biology. 29: 1493-1500. DOI: 10.1016/S1357-2725(97)00089-7  0.289
1994 Budhram-Mahadeo V, Theil T, Morris PJ, Lillycrop KA, Moroy T, Latchman DS. The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells. Nucleic Acids Research. 22: 3092-8. PMID 8065921 DOI: 10.1093/nar/22.15.3092  0.289
1997 Liu YZ, Latchman DS. The octamer-binding proteins Oct-1 and Oct-2 repress the HIV long terminal repeat promoter and its transactivation by Tat. The Biochemical Journal. 155-8. PMID 9078256 DOI: 10.1042/Bj3220155  0.289
1993 Morris PJ, Dent CL, Ring CJ, Latchman DS. The octamer binding site in the HPV16 regulatory region produces opposite effects on gene expression in cervical and non-cervical cells. Nucleic Acids Research. 21: 1019-23. PMID 8383834 DOI: 10.1093/Nar/21.4.1019  0.289
1993 ORCHARD K, LANG G, HARRIS J, COLLINS M, LATCHMAN D. A Palindromic Element in the Human Immunodeficiency Virus Long Terminal Repeat Binds Retinoic Acid Receptors and Can Confer Retinoic Acid Responsiveness on a Heterologous Promoter Jaids Journal of Acquired Immune Deficiency Syndromes. 6: 440???445. DOI: 10.1097/00126334-199305000-00002  0.289
2002 Kumar S, Kalsi JK, Ravirajan CT, Latchman DS, Pearl LH, Isenberg DA. Molecular expression systems for anti-DNA antibodies - 2 Lupus. 11: 833-842. PMID 12529048 DOI: 10.1191/0961203302Lu304Rr  0.289
1999 Stephanou A, Latchman DS, Isenberg DA. The regulation of heat shock proteins and their role in systemic lupus erythematosus. Seminars in Arthritis and Rheumatism. 28: 155-62. PMID 9872476 DOI: 10.1016/S0049-0172(98)80032-2  0.288
2004 Giles I, Lambrianides N, Latchman D, Chen P, Chukwuocha R, Isenberg D, Rahman A. The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin. Arthritis Research & Therapy. 7: R47-56. PMID 15642142 DOI: 10.1186/Ar1449  0.288
1992 Gerrelli D, Sharpe NG, Latchman DS. Cloning and sequencing of a mouse embryonal carcinoma cell mRNA encoding the tissue specific RNA splicing protein SmN. Nucleic Acids Research. 19: 6642. PMID 1754402 DOI: 10.1093/Nar/19.23.6642  0.288
2000 NDISANG D, BUDHRAM-MAHADEO V, SINGER A, LATCHMAN DS. Widespread elevated expression of the human papilloma virus (HPV)-activating cellular transcription factor Brn-3a in the cervix of women with CIN3 (cervical intraepithelial neoplasia stage 3) Clinical Science. 98: 601. DOI: 10.1042/Cs0980601  0.287
2002 Scarabelli TM, Stephanou A, Pasini E, Comini L, Raddino R, Knight RA, Latchman DS. Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury Circulation Research. 90: 745-748. PMID 11934844 DOI: 10.1161/01.Res.0000015224.07870.9A  0.286
1998 Wright MJ, Rosenthal E, Stewart L, Wightman LML, Miller AD, Latchman DS, Marber MS. β-Galactosidase staining following intracoronary infusion of cationic liposomes in the in vivo rabbit heart is produced by microinfarction rather than effective gene transfer: a cautionary tale Gene Therapy. 5: 301-308. PMID 9614549 DOI: 10.1038/Sj.Gt.3300590  0.286
1998 Liu YZ, Lee IK, Locke I, Dawson SJ, Latchman DS. Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles. Nucleic Acids Research. 26: 2464-72. PMID 9580701 DOI: 10.1093/Nar/26.10.2464  0.286
2010 Barry SP, Townsend PA, Knight RA, Scarabelli TM, Latchman DS, Stephanou A. STAT3 modulates the DNA damage response pathway International Journal of Experimental Pathology. 91: 506-514. PMID 20804538 DOI: 10.1111/J.1365-2613.2010.00734.X  0.286
1993 Grimaldi K, Horn DA, Hudson LD, Terenghi G, Barton P, Polak JM, Latchman DS. Expression of the SmN splicing protein is developmentally regulated in the rodent brain but not in the rodent heart. Developmental Biology. 156: 319-23. PMID 8462734 DOI: 10.1006/Dbio.1993.1080  0.285
2003 Mason MRJ, Lieberman AR, Latchman DS, Anderson PN. FKBP12 mRNA expression is upregulated by intrinsic CNS neurons regenerating axons into peripheral nerve grafts in the brain Experimental Neurology. 181: 181-189. PMID 12781991 DOI: 10.1016/S0014-4886(03)00038-4  0.285
2007 Lambrianides A, Giles I, Ioannou Y, Mason L, Latchman DS, Manson JJ, Isenberg DA, Rahman A. Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome Arthritis and Rheumatism. 56: 2392-2401. PMID 17599767 DOI: 10.1002/Art.22743  0.284
2003 Samady L, Costigliola E, MacCormac L, McGrath Y, Cleverley S, Lilley CE, Smith J, Latchman DS, Chain B, Coffin RS. Deletion of the virion host shutoff protein (vhs) from herpes simplex virus (HSV) relieves the viral block to dendritic cell activation: Potential of vhs- HSV vectors for dendritic cell-mediated immunotherapy Journal of Virology. 77: 3768-3776. PMID 12610151 DOI: 10.1128/Jvi.77.6.3768-3776.2003  0.284
1992 Dhillon V, Studd M, Isenberg D, Lehner T, Latchman D. Expression of the 90 kD heat shock protein in Behçet's syndrome. Autoimmunity. 12: 241-243. PMID 1343770 DOI: 10.3109/08916939209148465  0.284
2004 Brar BK, Jonassen AK, Egorina EM, Chen A, Negro A, Perrin MH, Mjøs OD, Latchman DS, Lee KF, Vale W. Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart. Endocrinology. 145: 24-35; discussion 21. PMID 12970163 DOI: 10.1210/En.2003-0689  0.283
2006 Giles I, Lambrianides N, Pattni N, Faulkes D, Latchman D, Chen P, Pierangeli S, Isenberg D, Rahman A. Arginine residues are important in determining the binding of human monoclonal antiphospholipid antibodies to clinically relevant antigens Journal of Immunology. 177: 1729-1736. PMID 16849482 DOI: 10.4049/Jimmunol.177.3.1729  0.283
2006 Ioannou Y, Giles I, Lambrianides A, Richardson C, Pearl LH, Latchman DS, Isenberg DA, Rahman A. A novel expression system of domain I of human beta2 glycoprotein I in Escherichia coli Bmc Biotechnology. 6. PMID 16472380 DOI: 10.1186/1472-6750-6-8  0.283
1996 Kendall G, Ensor E, Crankson HD, Latchman DS. Nerve growth factor treatment of sensory neuron primary cultures causes elevated levels of the mRNA encoding the ATP synthase beta-subunit as detected by a novel PCR-based differential cloning method. European Journal of Biochemistry. 236: 360-4. PMID 8612603 DOI: 10.1111/J.1432-1033.1996.00360.X  0.283
2000 Mockridge JW, Punn A, Latchman DS, Marber MS, Heads RJ. PKC-dependent delayed metabolic preconditioning is independent of transient MAPK activation. American Journal of Physiology. Heart and Circulatory Physiology. 279: H492-501. PMID 10924046 DOI: 10.1152/Ajpheart.2000.279.2.H492  0.282
1998 Smith MD, Ensor EA, Coffin RS, Boxer LM, Latchman DS. Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor. The Journal of Biological Chemistry. 273: 16715-22. PMID 9642226 DOI: 10.1074/Jbc.273.27.16715  0.282
2008 Yang YX, Latchman DS. Nurr1 transcriptionally regulates the expression of α-synuclein Neuroreport. 19: 867-871. PMID 18463503 DOI: 10.1097/Wnr.0B013E3282Ffda48  0.281
2008 Knight RA, Chen-Scarabelli C, Yuan Z, McCauley RB, Di Rezze J, Scarabelli GM, Townsend PA, Latchman D, Saravolatz L, Faggian G, Mazzucco A, Chowdrey HS, Stephanou A, Scarabelli TM. Cardiac release of urocortin precedes the occurrence of irreversible myocardial damage in the rat heart exposed to ischemia/reperfusion injury. Febs Letters. 582: 984-90. PMID 18295601 DOI: 10.1016/J.Febslet.2008.02.035  0.281
2006 Budhram-Mahadeo VS, Latchman DS. Targeting Brn-3b in breast cancer therapy Expert Opinion On Therapeutic Targets. 10: 15-25. PMID 16441225 DOI: 10.1517/14728222.10.1.15  0.281
2014 Croca S, Bassett P, Pericleous C, Alber KF, Latchman D, Isenberg D, Giles I, Rahman A, Ioannou Y. Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study. Arthritis Research & Therapy. 16: R48. PMID 24502558 DOI: 10.1186/Ar4477  0.281
1997 Cumming DV, Heads RJ, Watson A, Latchman DS, Yellon DM. Differential protection of primary rat cardiocytes by transfection of specific heat stress proteins. Journal of Molecular and Cellular Cardiology. 28: 2343-9. PMID 9004151 DOI: 10.1006/Jmcc.1996.0227  0.28
1989 Sharpe NG, Isenberg D, Williams DG, Latchman DS. Elevation of the levels of SmB, B' and D proteins but not that of the La (SS-B) antigen during HSV infections. Journal of Autoimmunity. 2: 701-8. PMID 2803478 DOI: 10.1016/S0896-8411(89)80008-3  0.28
2003 Stephanou A, Scarabelli TM, Lawrence K, Townsend P, Chen-Scarabelli C, Knight R, Latchman D. Green tea inhibits stat-1 activation and reduces apoptosis in cardiac myocytes exposed to ischemia/reperfusion injury Journal of the American College of Cardiology. 41: 374. DOI: 10.1016/S0735-1097(03)81053-7  0.28
2019 Kendall G, Latchman DS. Polymerase Chain Reaction for RNA Analysis Methods (San Diego, Calif.). 10: 279-82. PMID 8954838 DOI: 10.1006/Meth.1996.0103  0.279
2005 Bandopadhyay R, Kingsbury AE, Muqit MM, Harvey K, Reid AR, Kilford L, Engelender S, Schlossmacher MG, Wood NW, Latchman DS, Harvey RJ, Lees AJ. Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition Neurobiology of Disease. 20: 401-411. PMID 15894486 DOI: 10.1016/J.Nbd.2005.03.021  0.279
1998 Coffin RS, Thomas SK, Thomas NS, Lilley CE, Pizzey AR, Griffiths CH, Gibb BJ, Wagstaff MJ, Inges SJ, Binks MH, Chain BM, Thrasher AJ, Rutault K, Latchman DS. Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry. Gene Therapy. 5: 718-22. PMID 9797879 DOI: 10.1038/Sj.Gt.3300634  0.279
1997 Menon S, Rahman MA, Ravirajan CT, Kandiah D, Longhurst CM, McNally T, Williams WM, Latchman DS, Isenberg DA. The production, binding characteristics and sequence analysis of four human IgG monoclonal antiphospholipid antibodies. Journal of Autoimmunity. 10: 43-57. PMID 9080299 DOI: 10.1006/Jaut.1996.0106  0.279
2009 Ioannou Y, Romay-Penabad Z, Pericleous C, Giles I, Papalardo E, Vargas G, Shilagard T, Latchman DS, Isenberg DA, Rahman A, Pierangeli S. In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of β2-glycoprotein I: Proof of concept Journal of Thrombosis and Haemostasis. 7: 833-842. PMID 19220729 DOI: 10.1111/J.1538-7836.2009.03316.X  0.278
1998 Ravirajan CT, Rahman MA, Papadaki L, Griffiths MH, Kalsi J, Martin AC, Ehrenstein MR, Latchman DS, Isenberg DA. Genetic, structural and functional properties of an IgG DNA-binding monoclonal antibody from a lupus patient with nephritis. European Journal of Immunology. 28: 339-50. PMID 9485213 DOI: 10.1002/(Sici)1521-4141(199801)28:01<339::Aid-Immu339>3.0.Co;2-C  0.277
2007 Barry SP, Townsend PA, Latchman DS, Stephanou A. Role of the JAK-STAT pathway in myocardial injury Trends in Molecular Medicine. 13: 82-89. PMID 17194625 DOI: 10.1016/J.Molmed.2006.12.002  0.277
1992 Yellon DM, Iliodromitis E, Latchman DS, Van Winkle DM, Downey JM, Williams FM, Williams TJ. Whole body heat stress fails to limit infarct size in the reperfused rabbit heart. Cardiovascular Research. 26: 342-6. PMID 1638564 DOI: 10.1093/Cvr/26.4.342  0.277
1997 Liu YZ, Lania L, Latchman DS. Functional interaction between the HIV-1 Tat transactivator and the inhibitory domain of the Oct-2 cellular transcription factor. Aids (London, England). 10: 1323-9. PMID 8902060 DOI: 10.1097/00002030-199610000-00003  0.276
2007 Townsend PA, Davidson SM, Clarke SJ, Khaliulin I, Carroll CJ, Scarabelli TM, Knight RA, Stephanou A, Latchman DS, Halestrap AP. Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress American Journal of Physiology - Heart and Circulatory Physiology. 293: H928-H938. PMID 17483234 DOI: 10.1152/Ajpheart.01135.2006  0.276
1993 Huntriss JD, Latchman DS, Williams DG. Lupus autoantibodies discriminate between the highly homologous Sm polypeptides B/B' and SmN by binding an epitope restricted to B/B'. Clinical and Experimental Immunology. 92: 263-7. PMID 7683587 DOI: 10.1111/J.1365-2249.1993.Tb03390.X  0.276
2003 Sindos M, Ndisang D, Pisal N, Chow C, Singer A, Latchman DS. Measurement of Brn-3a levels in Pap smears provides a novel diagnostic marker for the detection of cervical neoplasia Gynecologic Oncology. 90: 366-371. PMID 12893201 DOI: 10.1016/S0090-8258(03)00261-0  0.275
2005 Chen-Scarabelli C, Hughes SE, Landon G, Rowley P, Allebban Z, Lawson N, Saravolatz L, Gardin J, Latchman D, Scarabelli TM. A case of fatal ephedra intake associated with lipofuscin accumulation, caspase activation and cleavage of myofibrillary proteins. European Journal of Heart Failure. 7: 927-30. PMID 16054866 DOI: 10.1016/J.Ejheart.2004.09.012  0.274
1992 Jang KL, Latchman DS. The herpes simplex virus immediate-early protein ICP27 stimulates the transcription of cellular Alu repeated sequences by increasing the activity of transcription factor TFIIIC Biochemical Journal. 284: 667-673. PMID 1320373 DOI: 10.1042/bj2840667  0.274
2010 Ndisang D, Khan A, Lorenzato F, Sindos M, Singer A, Latchman DS. The cellular transcription factor Brn-3a and the smoking-related substance nicotine interact to regulate the activity of the HPV URR in the cervix Oncogene. 29: 2701-2711. PMID 20190800 DOI: 10.1038/Onc.2010.33  0.274
1991 Williams DG, Sharpe NG, Wallace G, Latchman DS. A repeated proline-rich sequence in Sm B/B' and N is a dominant epitope recognized by human and murine autoantibodies. Journal of Autoimmunity. 3: 715-25. PMID 1708261 DOI: 10.1016/S0896-8411(05)80038-1  0.274
2001 Wright MJ, Wightman LML, Latchman DS, Marber MS. In vivo myocardial gene transfer: Optimization and evaluation of intracoronary gene delivery in vivo Gene Therapy. 8: 1833-1839. PMID 11821936 DOI: 10.1038/Sj.Gt.3301614  0.273
1993 Howard MK, Mailhos C, Dent CL, Latchman DS. Transactivation by the herpes simplex virus virion protein Vmw65 and viral permissivity in a neuronal cell line with reduced levels of the cellular transcription factor Oct-1 Experimental Cell Research. 207: 194-196. PMID 8391464 DOI: 10.1006/excr.1993.1180  0.273
1992 Heads RJ, Patel VC, Latchman DS, Yellon DM. Ischaemic preconditioning causes rapid elevation of 65kDa stress protein in rabbit heart Journal of Molecular and Cellular Cardiology. 24: 94. DOI: 10.1016/0022-2828(92)90307-L  0.273
2005 Kumar S, Bunting KA, Kalsi J, Hinks JA, Latchman DS, Pearl LH, Isenberg DA. Lupus autoantibodies to native DNA preferentially bind DNA presented on PolIV Immunology. 114: 418-427. PMID 15720443 DOI: 10.1111/J.1365-2567.2005.02090.X  0.273
2002 Schulman D, Latchman DS, Yellon DM. Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway American Journal of Physiology - Heart and Circulatory Physiology. 283: H1481-H1488. PMID 12234800 DOI: 10.1152/Ajpheart.01089.2001  0.272
2004 Scarabelli TM, Stephanou A, Pasini E, Gitti G, Townsend P, Lawrence K, Chen-Scarabelli C, Saravolatz L, Latchman D, Knight R, Gardin J. Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. Journal of the American College of Cardiology. 43: 865-74. PMID 14998631 DOI: 10.1016/J.Jacc.2003.09.050  0.272
2012 Latchman DS, Kemp LM. Growth of herpes simplex virus and purification of viral DNA. Methods in Molecular Biology (Clifton, N.J.). 8: 191-200. PMID 21390712 DOI: 10.1385/0-89603-191-8:191  0.272
2011 Ulgen BO, Field MG, Qureshi W, Knight RA, Stephanou A, Latchman DS, Vasquez D, Barry SP, Saravolatz L, Scarabelli GM, Faggian G, Mazzucco A, Carol-Chen-Scarabelli, Scarabelli TM. The role of minocycline in ischemia-reperfusion injury: A comprehensive review of an old drug with new implications Recent Patents On Cardiovascular Drug Discovery. 6: 123-132. PMID 21599619 DOI: 10.2174/157489011795933783  0.271
2006 Muqit MM, Abou-Sleiman PM, Saurin AT, Harvey K, Gandhi S, Deas E, Eaton S, Payne Smith MD, Venner K, Matilla A, Healy DG, Gilks WP, Lees AJ, Holton J, Revesz T, ... ... Latchman DS, et al. Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress. Journal of Neurochemistry. 98: 156-69. PMID 16805805 DOI: 10.1111/J.1471-4159.2006.03845.X  0.271
2001 Baxter GF, Mocanu MM, Brar BK, Latchman DS, Yellon DM. Cardioprotective effects of transforming growth factor-β1 during early reoxygenation or reperfusion are mediated by p42/p44 MAPK Journal of Cardiovascular Pharmacology. 38: 930-939. PMID 11707697 DOI: 10.1097/00005344-200112000-00015  0.271
1993 Yellon DM, Latchman DS, Marber MS. Stress proteins--an endogenous route to myocardial protection: fact or fiction? Cardiovascular Research. 27: 158-61. PMID 8472265 DOI: 10.1093/Cvr/27.2.158  0.27
2009 Yang YX, Wood NW, Latchman DS. Molecular basis of Parkinson's disease Neuroreport. 20: 150-156. PMID 19151598 DOI: 10.1097/Wnr.0B013E32831C50Df  0.27
2003 Smith J, Thomas SK, Coffin RS, Latchman DS. Examination of the potential interactions between herpes simplex virus vectors and replication-competent virus in vitro and in vivo Gene Therapy and Regulation. 2: 29-47. DOI: 10.1163/156855803762295413  0.269
1998 Smith MD, Dawson SJ, Boxer LM, Latchman DS. The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression. Nucleic Acids Research. 26: 4100-7. PMID 9722627 DOI: 10.1093/Nar/26.18.4100  0.268
2009 Ndisang D, Lorenzato F, Sindos M, Khan A, Singer A, Latchman DS. The HPV Cellular Transactivator Brn-3a Can Be Used to Predict Cervical Adenocarcinoma and Squamous Carcinoma Precancer Lesions in the Developed and Developing Worlds. Obstetrics and Gynecology International. 2009: 359457. PMID 20224757 DOI: 10.1155/2009/359457  0.268
1992 Yellon DM, Latchman DS. Stress proteins and myocardial protection. Journal of Molecular and Cellular Cardiology. 24: 113-24. PMID 1583697 DOI: 10.1016/0022-2828(92)93148-D  0.268
2008 Diss JK, Fraser SP, Walker MM, Patel A, Latchman DS, Djamgoz MB. Beta-subunits of voltage-gated sodium channels in human prostate cancer: quantitative in vitro and in vivo analyses of mRNA expression. Prostate Cancer and Prostatic Diseases. 11: 325-33. PMID 17893701 DOI: 10.1038/Sj.Pcan.4501012  0.268
1991 Orchard K, Perkins N, Chapman C, Harris J, Emery V, Goodwin G, Latchman D, Collins M. A T-cell protein which recognizes a palindromic DNA sequence in the negative regulatory element of the HIV-1 long terminal repeat with homology to steroid/thyroid hormone receptor binding sites. Biochemical Society Transactions. 18: 555-6. PMID 2276432 DOI: 10.1042/Bst0180555  0.267
2013 Pericleous C, Clarke LA, Brogan PA, Latchman DS, Isenberg DA, Ioannou Y, Giles IP, Rahman A. Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome Thrombosis and Haemostasis. 109: 72-78. PMID 23152159 DOI: 10.1160/Th12-05-0346  0.267
1990 LEA I, MOORE A, LATCHMAN D, MOORE H. Temporal expression and characterisation of a testis expressed mRNA Cell Biology International Reports. 14: 165. DOI: 10.1016/0309-1651(90)90762-N  0.266
1991 Latchman DS. Heat-shock proteins The Lancet. 337: 424. PMID 1671438 DOI: 10.1016/0140-6736(91)91196-2  0.265
2000 Latchman DS. Herpes virus vectors for gene therapy in the nervous system. Biochemical Society Transactions. 27: 847-51. PMID 10830115 DOI: 10.1042/Bst0270847  0.265
1997 Smith MD, Morris PJ, Dawson SJ, Schwartz ML, Schlaepfer WW, Latchman DS. Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor. The Journal of Biological Chemistry. 272: 21325-33. PMID 9261145 DOI: 10.1074/Jbc.272.34.21325  0.265
2003 Giles IP, Isenberg DA, Latchman DS, Rahman A. How do antiphospholipid antibodies bind β2-glycoprotein I? Arthritis and Rheumatism. 48: 2111-2121. PMID 12905463 DOI: 10.1002/Art.11101  0.264
1988 Kemp LM, Latchman DS. The herpes simplex virus type 1 immediate-early protein ICP4 specifically induces increased transcription of the human ubiquitin B gene without affecting the ubiquitin A and C genes. Virology. 166: 258-61. PMID 2842951 DOI: 10.1016/0042-6822(88)90170-5  0.263
1999 Rahman A, Latchman DS, Isenberg DA. Immunoglobulin variable region sequences of human monoclonal anti-DNA antibodies. Seminars in Arthritis and Rheumatism. 28: 141-54. PMID 9872475 DOI: 10.1016/S0049-0172(98)80031-0  0.262
2005 van der Weerd L, Lythgoe MF, Badin RA, Valentim LM, Akbar MT, de Belleroche JS, Latchman DS, Gadian DG. Neuroprotective effects of HSP70 overexpression after cerebral ischaemia--an MRI study. Experimental Neurology. 195: 257-66. PMID 15936758 DOI: 10.1016/J.Expneurol.2005.05.002  0.262
1993 Willoughby JJ, Ninkina NN, Beech MM, Latchman DS, Wood JN. Molecular cloning of a human neuronal nicotinic acetylcholine receptor beta 3-like subunit. Neuroscience Letters. 155: 136-9. PMID 7690916 DOI: 10.1016/0304-3940(93)90691-D  0.261
1995 Towers G, Harris J, Lang G, Collins MK, Latchman DS. Retinoic acid inhibits both the basal activity and phorbol ester-mediated activation of the HIV long terminal repeat promoter Aids. 9: 129-136. DOI: 10.1097/00002030-199502000-00003  0.26
2013 Bourke LT, Knight RA, Latchman DS, Stephanou A, McCormick J. Signal transducer and activator of transcription-1 localizes to the mitochondria and modulates mitophagy. Jak-Stat. 2: e25666. PMID 24470977 DOI: 10.4161/jkst.25666  0.26
2003 Townsend P, Scarabelli TM, Lawrence K, Stephanou A, Christopher C, Chen-Scarabelli C, Cutress R, Packham G, Latchman D. Bag-1 relocates within cardiac myocytes following ischemia/reperfusion and prevents myocyte apoptosis by interaction with Hsc70 Journal of the American College of Cardiology. 41: 374. DOI: 10.1016/S0735-1097(03)81054-9  0.26
1993 Marber MS, Walker JM, Latchman DS, Yellon DM. Attenuation by heat stress of a submaximal calcium paradox in the rabbit heart. Journal of Molecular and Cellular Cardiology. 25: 1119-26. PMID 8283475 DOI: 10.1006/Jmcc.1993.1124  0.259
2004 Ravirajan CT, Wang Y, Matis LA, Papadaki L, Griffiths MH, Latchman DS, Isenberg DA. Effect of neutralizing antibodies to IL-10 and C5 on the renal damage caused by a pathogenic human anti-dsDNA antibody Rheumatology. 43: 442-447. PMID 15024133 DOI: 10.1093/Rheumatology/Keh083  0.259
1994 Blanco F, Longhurst C, Watts R, Kalsi J, Wiloch HW, Youinou P, Latchman DS, Isenberg DA. Identification and characterization of a new human DNA reactive monoclonal antibody and a common idiotype, WRI 176 Id beta. Lupus. 3: 15-24. PMID 8025580 DOI: 10.1177/096120339400300105  0.258
2001 Brar BK, Stephanou A, Pennica D, Latchman DS. CT-1 mediated cardioprotection against ischaemic re-oxygenation injury is mediated by PI3 kinase, Akt and MEK1/2 pathways Cytokine. 16: 93-96. PMID 11741348 DOI: 10.1006/Cyto.2001.0951  0.258
2005 Latchman DS. Hsp27 and cell survival in neurones International Journal of Hyperthermia. 21: 393-402. PMID 16048837 DOI: 10.1080/02656730400023664  0.258
1990 Kemp LM, Gelman IH, Silverstein SJ, Latchman DS. Regulation of herpes simplex virus immediate-early gene promoters in mouse neuroblastoma cells Neuroscience Letters. 118: 185-188. PMID 2177173 DOI: 10.1016/0304-3940(90)90622-G  0.258
2004 Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, Ali Z, Del Turco D, Bentivoglio AR, Healy DG, Albanese A, Nussbaum R, González-Maldonado R, Deller T, Salvi S, ... ... Latchman DS, et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science (New York, N.Y.). 304: 1158-60. PMID 15087508 DOI: 10.1126/Science.1096284  0.258
2003 Scarabelli TM, Pasini E, Ferrari G, Ferrari M, Stephanou A, Townsend P, Lawrence K, chen-Scarabelli C, Knight R, Latchman D. Warm blood cardioplegia induces mitochondria- initiated myocyte apoptosis which is ameliorated by overexpression of endogeneous urocortin Journal of the American College of Cardiology. 41: 514. DOI: 10.1016/S0735-1097(03)82779-1  0.257
2015 Pericleous C, Ruiz-Limón P, Romay-Penabad Z, Marín AC, Garza-Garcia A, Murfitt L, Driscoll PC, Latchman DS, Isenberg DA, Giles I, Ioannou Y, Rahman A, Pierangeli SS. Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis. Rheumatology (Oxford, England). 54: 722-7. PMID 25273993 DOI: 10.1093/Rheumatology/Keu360  0.256
2000 Latchman DS. Herpes simplex virus vectors for gene therapy in Parkinson's disease and other diseases of the nervous system. Journal of the Royal Society of Medicine. 92: 566-70. PMID 10703493 DOI: 10.1177/014107689909201107  0.256
2003 Kumar S, Nagl S, Kalsi JK, Ravirajan CT, Athwal D, Latchman DS, Pearl LH, Isenberg DA. Anti-cardiolipin/beta-2 glycoprotein activities co-exist on human anti-DNA antibody light chains. Molecular Immunology. 40: 517-30. PMID 14563371 DOI: 10.1016/S0161-5890(03)00225-6  0.255
2001 Brar BK, Stephanou A, Liao Z, O'Leary RM, Pennica D, Yellon DM, Latchman DS. Cardiotrophin-1 can protect cardiac myocytes from injury when added both prior to simulated ischaemia and at reoxygenation Cardiovascular Research. 51: 265-274. PMID 11470466 DOI: 10.1016/S0008-6363(01)00294-2  0.255
1997 Dollery C, McClelland A, Rollence M, Stevenson S, Latchman D, Henney A, Humphries S, McEwan J. In Vivo and in Vitro Vascular Gene Transfer of Timp-1 Using an Adenoviral Vector Clinical Science. 93: 28P-28P. DOI: 10.1042/Cs093028P  0.254
2003 Thomas GR, Latchman DS. The pro-oncoprotein EWS (Ewing's Sarcoma protein) interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription. Cancer Biology & Therapy. 1: 428-32. PMID 12432261 DOI: 10.4161/cbt.1.4.23  0.254
2005 Fauchon MAC, Pell TJ, Baxter GF, Yellon DM, Latchman DS, Hubank MF, Mayne LV. Representational difference analysis of cDNA identifies novel genes expressed following preconditioning of the heart Experimental and Molecular Medicine. 37: 311-322. PMID 16155408  0.254
1994 Heads RJ, Latchman DS, Yellon DM. Stable high level expression of a transfected human HSP70 gene protects a heart-derived muscle cell line against thermal stress. Journal of Molecular and Cellular Cardiology. 26: 695-9. PMID 8089850 DOI: 10.1006/jmcc.1994.1084  0.254
2009 Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW, Duchen MR, Abramov AY. PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. Molecular Cell. 33: 627-38. PMID 19285945 DOI: 10.1016/J.Molcel.2009.02.013  0.252
1999 Coffin RS, Thomas SK, Thomas DP, Latchman DS. The herpes simplex virus 2 kb latency associated transcript (LAT) leader sequence allows efficient expression of downstream proteins which is enhanced in neuronal cells: possible function of LAT ORFs. The Journal of General Virology. 3019-26. PMID 9880017 DOI: 10.1099/0022-1317-79-12-3019  0.252
2000 Jonassen AK, Brar BK, Mjøs OD, Sack MN, Latchman DS, Yellon DM. Insulin administered at reoxygenation exerts a cardioprotective effect in myocytes by a possible anti-apoptotic mechanism. Journal of Molecular and Cellular Cardiology. 32: 757-64. PMID 10775481 DOI: 10.1006/Jmcc.2000.1118  0.25
2001 Mason LJ, Ravirajan CT, Latchman DS, Isenberg DA. A human anti-dsDNA monoclonal antibody caused hyaline thrombi formation in kidneys of 'leaky' SCID mice Clinical and Experimental Immunology. 126: 137-142. PMID 11678910 DOI: 10.1046/J.1365-2249.2001.01651.X  0.25
2003 Giles IP, Haley JD, Nagl S, Isenberg DA, Latchman DS, Rahman A. A systematic analysis of sequences of human antiphospholipid and anti-beta2-glycoprotein I antibodies: the importance of somatic mutations and certain sequence motifs. Seminars in Arthritis and Rheumatism. 32: 246-65. PMID 12621590 DOI: 10.1053/Sarh.2003.49994  0.248
2005 Chanalaris A, Lawrence KM, Townsend PA, Davidson S, Jashmidi Y, Stephanou A, Knight RD, Hsu SY, Hsueh AJW, Latchman DS. Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway Biochemical and Biophysical Research Communications. 328: 442-448. PMID 15694367 DOI: 10.1016/J.Bbrc.2005.01.001  0.247
2005 Stephanou A, Latchman DS. Opposing actions of STAT-1 and STAT-3 Growth Factors. 23: 177-182. PMID 16243709 DOI: 10.1080/08977190500178745  0.247
2007 Ioannou Y, Pericleous C, Giles I, Latchman DS, Isenberg DA, Rahman A. Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human β2-glycoprotein I: Mutation studies including residues R39 to R43 Arthritis and Rheumatism. 56: 280-290. PMID 17195232 DOI: 10.1002/Art.22306  0.247
1989 Latchman DS, Partridge JF, Estridge JK, Kemp LM. The different competitive abilities of viral TAATGARAT elements and cellular octamer motifs, mediate the induction of viral immediate-early genes and the repression of the histone H2B gene in herpes simplex virus infected cells Nucleic Acids Research. 17: 8533-8542. PMID 2555775 DOI: 10.1093/nar/17.21.8533  0.247
2008 Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, Downward J, Mansfield L, Jat P, Taylor J, Heales S, ... ... Latchman D, et al. Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons Plos One. 3. DOI: 10.1371/Annotation/17D5Aaa1-C6D8-4Aad-A9A4-56B2C1220C83  0.246
1989 Kemp LM, Latchman DS. Regulated transcription of herpes simplex virus immediate-early genes in neuroblastoma cells. Virology. 171: 607-10. PMID 2548331 DOI: 10.1016/0042-6822(89)90631-4  0.246
2001 Schulman D, Latchman DS, Yellon DM. Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury American Journal of Physiology - Heart and Circulatory Physiology. 281: H1630-H1636. PMID 11557553 DOI: 10.1152/Ajpheart.2001.281.4.H1630  0.246
1999 Dollery CM, Humphries SE, McClelland A, Latchman DS, McEwan JR. In vivo adenoviral gene transfer of TIMP-1 after vascular injury reduces neointimal formation. Annals of the New York Academy of Sciences. 878: 742-3. PMID 10415824 DOI: 10.1111/J.1749-6632.1999.Tb07778.X  0.245
2004 Valente E, Abou-Sleiman P, Caputo V, Muqit M, Gispert S, Ali Z, Del Turco D, Wingerter O, Bentivoglio A, Healy D, Albanese A, Nussbaum R, Gonzalez-Maldonado R, Deller T, Mülsch A, ... ... Latchman D, et al. Die PARK6-Form der Parkinson'schen Krankheit wird ausgelöst durch Mutationen in einer mitochondrialen Protein-Kinase Aktuelle Neurologie. 31. DOI: 10.1055/S-2004-832984  0.245
2005 Collino M, Patel NSA, Lawrence KM, Collin M, Latchman DS, Yaqoob MM, Thiemermann C. The selective PPARγ antagonist GW9662 reverses the protection of LPS in a model of renal ischemia-reperfusion Kidney International. 68: 529-536. PMID 16014029 DOI: 10.1111/J.1523-1755.2005.00430.X  0.244
2011 Lambrianides A, Turner-Stokes T, Pericleous C, Ehsanullah J, Papadimitraki E, Poulton K, Ioannou Y, Lawrie A, Mackie I, Chen P, Latchman D, Isenberg D, Rahman A, Giles I. Interactions of human monoclonal and polyclonal antiphospholipid antibodies with serine proteases involved in hemostasis. Arthritis and Rheumatism. 63: 3512-21. PMID 21739425 DOI: 10.1002/Art.30525  0.243
2004 Scarabelli TM, Pasini E, Stephanou A, Chen-Scarabelli C, Saravolatz L, Knight RA, Latchman DS, Gardin JM. Nutritional supplementation with mixed essential amino acids enhances myocyte survival, preserving mitochondrial functional capacity during ischemia-reperfusion injury. The American Journal of Cardiology. 93: 35A-40A. PMID 15094104 DOI: 10.1016/J.Amjcard.2003.11.008  0.243
2004 Sindos M, Ndisang D, Pisal N, Chow C, Deery A, Singer A, Latchman D. Detection of cervical neoplasia using measurement of Brn-3a in cervical smears with persistent minor abnormality. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 13: 515-7. PMID 12911730 DOI: 10.1046/J.1525-1438.2003.13303.X  0.242
1992 Walker DM, Kucukoglu S, Pasini E, Marber MS, Latchman DS, Yellon DM. The effect of Heat Stress on infarct size in blood vs buffer perfused rabbit hearts Journal of Molecular and Cellular Cardiology. 24: 118. DOI: 10.1016/0022-2828(92)90379-E  0.242
1991 Latchman DS. Herpes simplex virus life cycle and the design of viral vectors. Methods of Molecular Biology. 8: 175-190. PMID 21390711 DOI: 10.1385/0-89603-191-8:175  0.242
1998 Stephanou A, Okosi A, Knight RA, Chowdrey HS, Latchman DS. C/EBP activates the human corticotropin-releasing hormone gene promoter. Molecular and Cellular Endocrinology. 134: 41-50. PMID 9406848 DOI: 10.1016/S0303-7207(97)00170-6  0.242
2005 Kumar S, Nagl S, Kalsi JK, Ravirajan CT, Athwal D, Latchman DS, Pearl LH, Isenberg DA. Beta-2-glycoprotein specificity of human anti-phospholipid antibody resides on the light chain: A novel mechanism for acquisition of cross-reactivity by an autoantibody Molecular Immunology. 42: 39-48. PMID 15488942 DOI: 10.1016/J.Molimm.2004.07.012  0.241
2005 Hudson CD, Morris PJ, Latchman DS, Budhram-Mahadeo VS. Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate Journal of Biological Chemistry. 280: 11851-11858. PMID 15598651 DOI: 10.1074/jbc.M408679200  0.24
2004 Latchman DS. Protective effect of heat shock proteins in the nervous system. Current Neurovascular Research. 1: 21-7. PMID 16181063  0.24
1999 Dollery CM, Humphries SE, McClelland A, Latchman DS, McEwan JR. Expression of tissue inhibitor of matrix metalloproteinases 1 by use of an adenoviral vector inhibits smooth muscle cell migration and reduces neointimal hyperplasia in the rat model of vascular balloon injury. Circulation. 99: 3199-205. PMID 10377085 DOI: 10.1161/01.Cir.99.24.3199  0.239
1992 Chapman CJ, Harris JD, Collins MK, Latchman DS. A recombinant HIV provirus is synergistically activated by the HIV Tat protein and the HSV IE1 protein but not by the HSV IE3 protein. Aids (London, England). 5: 945-50. PMID 1777175 DOI: 10.1097/00002030-199108000-00004  0.239
2002 Janjua S, Stephanou A, Latchman DS. The C-terminal activation domain of the STAT-1 transcription factor is necessary and sufficient for stress-induced apoptosis Cell Death and Differentiation. 9: 1140-1146. PMID 12232802 DOI: 10.1038/sj.cdd.4401082  0.238
1999 Liu YZ, Chrivia JC, Latchman DS. Nerve growth factor up-regulates the transcriptional activity of CBP through activation of the p42/p44(MAPK) cascade. The Journal of Biological Chemistry. 273: 32400-7. PMID 9829969 DOI: 10.1074/Jbc.273.49.32400  0.237
2000 Stephanou A, Brar BK, Scarabelli TM, Jonassen AK, Yellon DM, Marber MS, Knight RA, Latchman DS. Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis. The Journal of Biological Chemistry. 275: 10002-8. PMID 10744676 DOI: 10.1074/jbc.275.14.10002  0.237
2006 Smart N, Mojet MH, Latchman DS, Marber MS, Duchen MR, Heads RJ. IL-6 induces PI 3-kinase and nitric oxide-dependent protection and preserves mitochondrial function in cardiomyocytes Cardiovascular Research. 69: 164-177. PMID 16219301 DOI: 10.1016/J.Cardiores.2005.08.017  0.234
2002 Scarabelli TM, Stephanou A, Chen-Scarabelli CA, Knight RA, Latchman DS. Myocardial apoptosis following short periods of ischemia in the isolated rat heart: a hypothetical cut off point for experimental simulated angina? Journal of the American College of Cardiology. 39: 325. DOI: 10.1016/S0735-1097(02)81460-7  0.233
1996 Rahman A, Isenberg DA, Latchman DS. Monoclonal antiphospholipid antibodies and germline VH genes: comment on the article by Harmer et al. Arthritis and Rheumatism. 39: 537-8. PMID 8607907 DOI: 10.1002/Art.1780390327  0.233
2002 Brar BK, Railson J, Stephanou A, Knight RA, Latchman DS. Urocortin increases the expression of heat shock protein 90 in rat cardiac myocytes in a MEK1/2-dependent manner Journal of Endocrinology. 172: 283-293. PMID 11834446 DOI: 10.1677/joe.0.1720283  0.233
2009 Francis YI, Fà M, Ashraf H, Zhang H, Staniszewski A, Latchman DS, Arancio O. Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 18: 131-9. PMID 19625751 DOI: 10.3233/Jad-2009-1134  0.233
2013 Barry SP, Ounzain S, McCormick J, Scarabelli TM, Chen-Scarabelli C, Saravolatz LII, Faggian G, Mazzucco A, Suzuki H, Thiemermann C, Knight RA, Latchman DS, Stephanou A. Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury International Journal of Cardiology. 163: 326-334. PMID 22030025 DOI: 10.1016/J.Ijcard.2011.08.849  0.233
2006 Ndisang D, Lorenzato F, Sindos M, Singer A, Latchman DS. Detection of cervical abnormalities in a developing country using measurement of Brn-3a in cervical smears Gynecologic Oncology. 100: 89-94. PMID 16126264 DOI: 10.1016/J.Ygyno.2005.07.109  0.23
2004 Farooqui-Kabir SR, Budhram-Mahadeo V, Lewis H, Latchman DS, Marber MS, Heads RJ. Regulation of Hsp27 expression and cell survival by the POU transcription factor Brn3a. Cell Death and Differentiation. 11: 1242-4. PMID 15272315 DOI: 10.1038/sj.cdd.4401478  0.229
1990 Zwaagstra JC, Ghiasi H, Slanina SM, Nesburn AB, Wheatley SC, Lillycrop K, Wood J, Latchman DS, Patel K, Wechsler SL. Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript. Journal of Virology. 64: 5019-5028. DOI: 10.1128/jvi.64.10.5019-5028.1990  0.228
1990 Kemp LM, Estridge JK, Brennan A, Katz DR, Latchman DS. Mononuclear phagocytes and HSV-1 infection: increased permissivity in differentiated U937 cells is mediated by post-transcriptional regulation of viral immediate-early gene expression. Journal of Leukocyte Biology. 47: 483-9. PMID 2161891 DOI: 10.1002/jlb.47.6.483  0.227
2005 Chanalaris A, Lawrence KM, Townsend PA, Davidson S, Jamshidi Y, Stephanou A, Knight RD, Hsu SY, Hsueh AJW, Latchman DS. Corrigendum to “Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway” [Biochem. Biophys. Res. Commun. 328 (2005) 442–448] Biochemical and Biophysical Research Communications. 330: 356-356. DOI: 10.1016/J.Bbrc.2005.02.124  0.227
1993 Latchman DS. Transcriptional regulation of viral gene expression Reviews in Medical Virology. 3: 115-122. DOI: 10.1002/rmv.1980030208  0.225
1999 Budhram-Mahadeo V, Morris PJ, Smith MD, Midgley CA, Boxer LM, Latchman DS. p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor. The Journal of Biological Chemistry. 274: 15237-44. PMID 10329733 DOI: 10.1074/Jbc.274.21.15237  0.225
2001 Stephanou A, Scarabelli TM, Brar BK, Nakanishi Y, Matsumura M, Knight RA, Latchman DS. Induction of Apoptosis and Fas Receptor/Fas Ligand Expression by Ischemia/Reperfusion in Cardiac Myocytes Requires Serine 727 of the STAT-1 Transcription Factor but Not Tyrosine 701 Journal of Biological Chemistry. 276: 28340-28347. PMID 11309387 DOI: 10.1074/jbc.M101177200  0.225
2008 Hudson CD, Sayan AE, Melino G, Knight RA, Latchman DS, Budhram-Mahadeo V. Brn-3a/POU4F1 interacts with and differentially affects p73-mediated transcription Cell Death and Differentiation. 15: 1266-1278. PMID 18421303 DOI: 10.1038/cdd.2008.45  0.223
2008 Latchman DS. Heat shock proteins: protective effect and potential therapeutic use (review). International Journal of Molecular Medicine. 2: 375-81. PMID 9857220 DOI: 10.3892/ijmm.2.4.375  0.223
1991 Latchman DS. The herpes simplex virus virion protein Vmw65 transcriptionally activates the gene encoding the U4 snRNA but not that encoding the U2 snRNA during lytic infection. The Biochemical Journal. 369-72. PMID 1850984 DOI: 10.1042/bj2750369  0.223
1999 Thomas SK, Lilley CE, Latchman DS, Coffin RS. Equine Herpesvirus 1 Gene 12 Can Substitute for vmw65 in the Growth of Herpes Simplex Virus (HSV) Type 1, Allowing the Generation of Optimized Cell Lines for the Propagation of HSV Vectors with Multiple Immediate-Early Gene Defects Journal of Virology. 73: 7399-7409. DOI: 10.1128/jvi.73.9.7399-7409.1999  0.221
2011 Stephanou A, Latchman DS. Transcriptional modulation of heat-shock protein gene expression. Biochemistry Research International. 2011: 238601. PMID 21152185 DOI: 10.1155/2011/238601  0.22
2011 Stephanou A, Latchman DS. Transcriptional modulation of heat-shock protein gene expression Biochemistry Research International. DOI: 10.1155/2011/238601  0.22
2004 Hudson CD, Podesta J, Henderson D, Latchman DS, Budhram-Mahadeo V. Coexpression of Brn-3a POU protein with p53 in a population of neuronal progenitor cells is associated with differentiation and protection against apoptosis Journal of Neuroscience Research. 78: 803-814. PMID 15532030 DOI: 10.1002/jnr.20299  0.22
2019 Barry SP, Ounzain S, McCormick J, Scarabelli TM, Chen-Scarabelli C, Saravolatz LII, Faggian G, Mazzucco A, Suzuki H, Thiemermann C, Knight RA, Latchman DS, Stephanou A. Retraction notice to "Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury" [Int. J. Cardiol. 163 (2013) 326-334]. International Journal of Cardiology. 274: 404. PMID 30449337 DOI: 10.1016/J.Ijcard.2018.10.031  0.219
2002 Liao Z, Brar BK, Cai Q, Stephanou A, O'Leary RM, Pennica D, Yellon DM, Latchman DS. Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion Cardiovascular Research. 53: 902-910. PMID 11922900 DOI: 10.1016/S0008-6363(01)00531-4  0.219
2003 Chanalaris A, Sun Y, Latchman DS, Stephanou A. SAG attenuates apoptotic cell death caused by simulated ischaemia/reoxygenation in rat cardiomyocytes Journal of Molecular and Cellular Cardiology. 35: 257-264. PMID 12676540 DOI: 10.1016/S0022-2828(03)00003-8  0.218
1992 Marber MS, Malcolm Walker J, Latchman DS, Yellon DM. The resistance of rabbit papillary muscle to high flow hypoxia is enhanced by heat stress when pyruvate is used as substrate Journal of Molecular and Cellular Cardiology. 24: 120. DOI: 10.1016/0022-2828(92)90386-E  0.217
2010 Morgan MD, Burke F, Biela C, Harper L, Gordon C, Young SP, Goulden BS, Turner-Stokes TJ, Pericleous C, Lambrianides A, Bell K, Ioannou Y, Latchman D, Isenberg D, Rahman A, et al. SLE and Antiphospholipid Syndrome [223-231]: 223. Acid Disruption Biacore Analysis of Antibodies Against Rituximab in SLE Patients Rheumatology. 49: i119-i122. DOI: 10.1093/Rheumatology/Keq728  0.217
1997 Latchman DS. Herpes simplex virus and risk of Alzheimer's disease. Lancet (London, England). 349: 1101; author reply 1. PMID 9107269 DOI: 10.1016/S0140-6736(05)62323-9  0.216
2005 Lawrence KM, Kabir AMN, Bellahcene M, Davidson S, Cao XB, McCormick J, Mesquita RA, Carroll CJ, Chanalaris A, Townsend PA, Hubank M, Stephanou A, Knight RA, Marber MS, Latchman DS. Cardioprotection mediated by urocortin is dependent on PKCε activation Faseb Journal. 19: 831-833. PMID 15764590 DOI: 10.1096/fj.04-2506fje  0.214
1987 Kemp LM, Preston CM, Preston VG, Latchman DS. Cellular gene induction during herpes simplex virus infection can occur without viral protein synthesis. Nucleic Acids Research. 14: 9261-70. PMID 3797240 DOI: 10.1093/nar/14.23.9261  0.213
1997 Cumming DV, Heads RJ, Coffin RS, Yellon DM, Latchman DS. Pharmacological preconditioning of primary rat cardiac myocytes by FK506. Basic Research in Cardiology. 91: 367-73. PMID 8922254 DOI: 10.1007/BF00788716  0.211
1999 Rahman A, Latchman D, Isenberg D. Sequence features of monoclonal antiphospholipid antibodies: comment on the article by Ikematsu et al. Arthritis and Rheumatism. 42: 1783-4. PMID 10446886 DOI: 10.1002/1529-0131(199908)42:8<1783::Aid-Anr37>3.0.Co;2-T  0.206
1996 Morris SD, Cumming DV, Latchman DS, Yellon DM. Specific induction of the 70-kD heat stress proteins by the tyrosine kinase inhibitor herbimycin-A protects rat neonatal cardiomyocytes. A new pharmacological route to stress protein expression? The Journal of Clinical Investigation. 97: 706-12. PMID 8609226 DOI: 10.1172/JCI118468  0.206
2006 Abou-Sleiman PM, Muqit MMK, McDonald NQ, Yang YX, Gandhi S, Healy DG, Harvey K, Harvey RJ, Deas E, Bhatia K, Quinn N, Lees A, Latchman DS, Wood NW. A heterozygous effect for PINK1 mutations in Parkinson's disease Annals of Neurology. 60: 414-419. PMID 16969854 DOI: 10.1002/Ana.20960  0.205
2004 Latchman DS, Stephanou A. STAT-1 and STAT-3: Closely related transcription factors with antagonistic effects on cell proliferation and apoptosis Current Genomics. 5: 453-457. DOI: 10.2174/1389202043349066  0.204
1988 Kemp LM, Latchman DS. Differential regulation of octamer-containing cellular genes by the herpes simplex virus virion protein Vmw65 is mediated by sequence differences in the octamer element. The Embo Journal. 7: 4239-4244. DOI: 10.1002/j.1460-2075.1988.tb03321.x  0.204
1987 Latchman DS. Herpes infection and AIDS. Nature. 325: 487-487. PMID 3027578 DOI: 10.1038/325487A0  0.202
2011 Carroll CJ, Suleman N, Davidson SM, Faulkes DJ, Diss JK, Knight R, Stephanou A, Latchman DS, Townsend PA. Transgenic overexpression of HSP56 does not result in cardiac hypertrophy nor protect from ischaemia/reperfusion injury International Journal of Biochemistry and Cell Biology. 43: 74-79. PMID 20932935 DOI: 10.1016/j.biocel.2010.09.020  0.201
2001 Gusterson R, Brar B, Faulkes D, Giordano A, Chrivia J, Latchman D. The transcriptional co-activators CBP and p300 are activated via phenylephrine through the p42/p44 MAPK cascade. The Journal of Biological Chemistry. 277: 2517-24. PMID 11705990 DOI: 10.1074/Jbc.M104626200  0.201
1992 Latchman D. No diabetes link to hsp65? Nature. 356: 114. PMID 1545859 DOI: 10.1038/356114C0  0.199
1995 Latchman D, Polak J. Analysis of Neuronal Gene Regulation and Differentiation Using the ND (Neuroblastoma-Dorsal Root Ganglion) Series of Cell Lines Methods. 7: 277-284. DOI: 10.1006/meth.1995.1033  0.199
1995 Latchman DS. The s(p)elling of apo(p)tosis. Nature. 375: 100. PMID 7753159 DOI: 10.1038/375100A0  0.198
1983 Scott MR, Brickell PM, Latchman DS, Murphy D, Westphal KH, Rigby PW. The use of cDNA cloning techniques to isolate genes activated in tumour cells. Haematology and Blood Transfusion. 28: 236-40. PMID 6305792 DOI: 10.1007/978-3-642-68761-7_45  0.196
2000 Brar BK, Jonassen AK, Stephanou A, Santilli G, Railson J, Knight RA, Yellon DM, Latchman DS. Urocortin protects against ischemic and reperfusion injury via a MAPK-dependent pathway. The Journal of Biological Chemistry. 275: 8508-14. PMID 10722688 DOI: 10.1074/jbc.275.12.8508  0.196
1989 Norton PM, Latchman DS. Levels of the 90kd heat shock protein and resistance to glucocorticoid-mediated cell killing in a range of human and murine lymphocyte cell lines. Journal of Steroid Biochemistry. 33: 149-54. PMID 2770294 DOI: 10.1016/0022-4731(89)90288-4  0.195
1990 Hyams J, Latchman D. Bid for the top Nature. 347: 584-584. DOI: 10.1038/347584A0  0.194
2009 Badin RA, Modo M, Cheetham M, Thomas DL, Gadian DG, Latchman DS, Lythgoe MF. Protective effect of post-ischaemic viral delivery of heat shock proteins in vivo. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 254-63. PMID 18781161 DOI: 10.1038/Jcbfm.2008.106  0.191
2004 Irshad S, Pedley RB, Anderson J, Latchman DS, Budhram-Mahadeo V. The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo. The Journal of Biological Chemistry. 279: 21617-27. PMID 14970234 DOI: 10.1074/jbc.M312506200  0.191
1991 Dent CL, McIndoe GA, Latchman DS. The constitutively expressed octamer binding protein OTF-1 and a novel octamer binding protein expressed specifically in cervical cells bind to an octamer-related sequence in the human papillomavirus 16 enhancer. Nucleic Acids Research. 19: 4531-5. PMID 1653419 DOI: 10.1093/nar/19.16.4531  0.19
1996 Latchman DS. Cell stress genes and neuronal protection. Neuropathology and Applied Neurobiology. 21: 475-7. PMID 8745232 DOI: 10.1111/j.1365-2990.1995.tb01089.x  0.19
2010 Berwick DC, Diss JKJ, Budhram-Mahadeo VS, Latchman DS. A simple technique for the prediction of interacting proteins reveals a direct Brn-3a-androgen receptor interaction Journal of Biological Chemistry. 285: 15286-15295. PMID 20228055 DOI: 10.1074/jbc.M109.071456  0.189
2002 Saurin AT, Pennington DJ, Raat NJH, Latchman DS, Owen MJ, Marber MS. Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts Cardiovascular Research. 55: 672-680. PMID 12160964 DOI: 10.1016/S0008-6363(02)00325-5  0.189
1998 Stephanou A, Brar B, Heads R, Knight RD, Marber MS, Pennica D, Latchman DS. Cardiotrophin-1 induces heat shock protein accumulation in cultured cardiac cells and protects them from stressful stimuli. Journal of Molecular and Cellular Cardiology. 30: 849-55. PMID 9602434 DOI: 10.1006/jmcc.1998.0651  0.188
1989 Jang KL, Latchman DS. HSV infection induces increased transcription of Alu repeated sequences by RNA polymerase III Febs Letters. 258: 255-258. PMID 2557237 DOI: 10.1016/0014-5793(89)81667-9  0.188
1993 Latchman DS. PCR in situ Hybridization: Protocols and Applications G. J. Nuovo. Raven Press, New York (1993). 276 pp. ISBN 0–88167–940–2 Reviews in Medical Virology. 3: 245-245. DOI: 10.1002/Rmv.1980030408  0.186
1998 Stephanou A, Isenberg DA, Akira S, Kishimoto T, Latchman DS. The nuclear factor interleukin-6 (NF-IL6) and signal transducer and activator of transcription-3 (STAT-3) signalling pathways co-operate to mediate the activation of the hsp90beta gene by interleukin-6 but have opposite effects on its inducibility by heat shock. The Biochemical Journal. 189-95. PMID 9461509 DOI: 10.1042/bj3300189  0.186
1994 Gerrelli D, Huntriss JD, Latchman DS. Antagonistic effects of retinoic acid and thyroid hormone on the expression of the tissue-specific splicing protein SmN in a clonal cell line derived from rat heart. Journal of Molecular and Cellular Cardiology. 26: 713-9. PMID 8089852 DOI: 10.1006/jmcc.1994.1086  0.184
2004 Jamshidi Y, Zourlidou A, Carroll CJ, Sinclair J, Latchman DS. Signal-transduction pathways involved in the hypertrophic effect of hsp56 in neonatal cardiomyocytes Journal of Molecular and Cellular Cardiology. 36: 381-392. PMID 15010277 DOI: 10.1016/j.yjmcc.2003.12.011  0.183
1996 Conroy SE, Latchman DS. Do heat shock proteins have a role in breast cancer? British Journal of Cancer. 74: 717-21. PMID 8795573 DOI: 10.1038/bjc.1996.427  0.179
2013 Chen-Scarabelli C, Saravolatz Ii L, McCaukey R, Scarabelli G, Di Rezze J, Mohanty B, Barry S, Latchman D, Georgiadis V, McCormick J, Saravolatz L, Knight R, Faggian G, Narula J, Stephanou A, et al. The cardioprotective effects of urocortin are mediated via activation of the Src tyrosine kinase-STAT3 pathway. Jak-Stat. 2: e24812. PMID 24069562 DOI: 10.4161/jkst.24812  0.176
2012 Mccormick J, Suleman N, Scarabelli TM, Knight RA, Latchman DS, Stephanou A. STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy Journal of Cellular and Molecular Medicine. 16: 386-393. PMID 21447043 DOI: 10.1111/j.1582-4934.2011.01323.x  0.175
1995 Latchman DS. Biochemistry (4th edn) Trends in Biochemical Sciences. 20: 488. DOI: 10.1016/S0968-0004(00)89112-4  0.173
2000 Latchman DS, Coffin RS. Viral vectors in the treatment of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 15: 9-17. PMID 10634236 DOI: 10.1002/1531-8257(200001)15:1<9::AID-MDS1004>3.0.CO;2-5  0.173
1990 Bansal GS, Latchman DS. Oestrogen enhances the responsiveness of the MMTV-LTR to glucocorticoid in ZR-75-1 human breast cancer cells Journal of Steroid Biochemistry. 36: 399-405. PMID 2170763 DOI: 10.1016/0022-4731(90)90080-C  0.173
1988 Latchman DS. Effect of herpes simplex virus type 2 infection on mitochondrial gene expression. The Journal of General Virology. 1405-10. PMID 2838578 DOI: 10.1099/0022-1317-69-6-1405  0.169
2010 Calissano M, Latchman DS. Cell-specific regulation of the pro-survival Brn-3b transcription factor by microRNAs Molecular and Cellular Neuroscience. 45: 317-323. PMID 20609388 DOI: 10.1016/j.mcn.2010.06.015  0.167
1990 Sharpe NG, Wall W, Latchman DS. Expression of the tissue specific RNA splicing protein SmN in HeLa cells. Nucleic Acids Research. 18: 3425-6. PMID 2356141 DOI: 10.1093/nar/18.11.3425  0.166
1991 Dent CL, Latchman DS. The overlapping octamer/TAATGARAT motif is a high-affinity binding site for the cellular transcription factors Oct-1 and Oct-2. The Biochemical Journal. 277: 541-5. PMID 1650186 DOI: 10.1042/bj2770541  0.165
2010 Fraser SP, Ozerlat-Gunduz I, Onkal R, Diss JK, Latchman DS, Djamgoz MB. Estrogen and non-genomic upregulation of voltage-gated Na(+) channel activity in MDA-MB-231 human breast cancer cells: role in adhesion. Journal of Cellular Physiology. 224: 527-39. PMID 20432453 DOI: 10.1002/jcp.22154  0.165
1998 Bolla MK, Miller GJ, Yellon DM, Evans A, Luc G, Cambou JP, Arveiler D, Cambien F, Latchman DS, Humphries SE, Day IN. Analysis of the association of a heat shock protein70-1 gene promoter polymorphism with myocardial infarction and coronary risk traits. Disease Markers. 13: 227-35. PMID 9553737 DOI: 10.1155/1998/235151  0.164
1998 Ndisdang D, Morris PJ, Chapman C, Ho L, Singer A, Latchman DS. The HPV-activating cellular transcription factor Brn-3a is overexpressed in CIN3 cervical lesions. The Journal of Clinical Investigation. 101: 1687-92. PMID 9541499 DOI: 10.1172/JCI1089  0.164
1996 Grenfell SJ, Latchman DS, Thomas NS. Oct-1 [corrected] and Oct-2 DNA-binding site specificity is regulated in vitro by different kinases. The Biochemical Journal. 889-93. PMID 8645173 DOI: 10.1042/bj3150889  0.162
2003 Kabakov A, Budagova K, Malyutina Y, Latchman D. 1P-0171 Hsp70 or Hsp27 overexpressed in endothelial cells during post-ischemic reperfusion may protect from delayed apoptosis Atherosclerosis Supplements. 4: 57-58. DOI: 10.1016/S1567-5688(03)90244-3  0.16
2002 Latchman DS. Urocortin. The International Journal of Biochemistry & Cell Biology. 34: 907-10. PMID 12007627 DOI: 10.1016/s1357-2725(02)00011-0  0.158
2003 Chanalaris A, Lawrence KM, Stephanou A, Knight RD, Hsu SY, Hsueh AJ, Latchman DS. Protective effects of the urocortin homologues stresscopin (SCP) and stresscopin-related peptide (SRP) against hypoxia/reoxygenation injury in rat neonatal cardiomyocytes. Journal of Molecular and Cellular Cardiology. 35: 1295-305. PMID 14519439 DOI: 10.1016/S0022-2828(03)00244-X  0.158
2002 Lawrence KM, Chanalaris A, Scarabelli T, Hubank M, Pasini E, Townsend PA, Comini L, Ferrari R, Tinker A, Stephanou A, Knight RA, Latchman DS. KATP channel gene expression is induced by urocortin and mediates its cardioprotective effect Circulation. 106: 1556-1562. PMID 12234964 DOI: 10.1161/01.CIR.0000028424.02525.AE  0.157
1998 Latchman DS. Transcription factors: an overview. The International Journal of Biochemistry & Cell Biology. 29: 1305-12. PMID 9570129 DOI: 10.1016/S1357-2725(97)00085-X  0.156
1998 Conroy SE, Sasieni PD, Amin V, Wang DY, Smith P, Fentiman IS, Latchman DS. Antibodies to heat-shock protein 27 are associated with improved survival in patients with breast cancer. British Journal of Cancer. 77: 1875-9. PMID 9667662 DOI: 10.1038/bjc.1998.312  0.154
2007 Latchman DS. Eukaryotic Transcription Factors Eukaryotic Transcription Factors.  0.153
2003 Latchman DS. Eukaryotic Transcription Factors: Fourth Edition Eukaryotic Transcription Factors: Fourth Edition. 1-364.  0.152
1986 Rose DS, Shriver K, Latchman DS, LaThangue NB. A filamentous distribution for the herpes simplex virus type 2-encoded major DNA-binding protein The Journal of General Virology. 67. PMID 3014046 DOI: 10.1099/0022-1317-67-7-1315  0.15
1999 Scarabelli TM, Knight RA, Rayment NB, Cooper TJ, Stephanou A, Brar BK, Lawrence KM, Santilli G, Latchman DS, Baxter GF, Yellon DM. Quantitative assessment of cardiac myocyte apoptosis in tissue sections using the fluorescence-based tunel technique enhanced with counterstains. Journal of Immunological Methods. 228: 23-8. PMID 10556539 DOI: 10.1016/S0022-1759(99)00090-3  0.149
1995 Faulds G, Conroy S, Madaio M, Isenberg D, Latchman D. Increased levels of antibodies to heat shock proteins with increasing age in Mrl/Mp-lpr/lpr mice. British Journal of Rheumatology. 34: 610-5. PMID 7670777 DOI: 10.1093/Rheumatology/34.7.610  0.148
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