Carmine Coscia - Publications

Affiliations: 
1965-2014 Biochemistry and Molecular Biology Saint Louis University School of Medicine, St. Louis, MO, United States 
Area:
Opioid Biosynthesis and Mechanism of Action
Website:
https://biochem.slu.edu

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Year Citation  Score
2014 Phamduong E, Rathore MK, Crews NR, D'Angelo AS, Leinweber AL, Kappera P, Krenning TM, Rendell VR, Belcheva MM, Coscia CJ. Acute and chronic mu opioids differentially regulate thrombospondins 1 and 2 isoforms in astrocytes. Acs Chemical Neuroscience. 5: 106-14. PMID 24304333 DOI: 10.1021/cn400172n  0.622
2010 Ikeda H, Miyatake M, Koshikawa N, Ochiai K, Yamada K, Kiss A, Donlin MJ, Panneton WM, Churchill JD, Green M, Siddiqui AM, Leinweber AL, Crews NR, Ezerskiy LA, Rendell VR, ... ... Coscia CJ, et al. Morphine modulation of thrombospondin levels in astrocytes and its implications for neurite outgrowth and synapse formation. The Journal of Biological Chemistry. 285: 38415-27. PMID 20889977 DOI: 10.1074/Jbc.M110.109827  0.627
2010 Hahn JW, Jagwani S, Kim E, Rendell VR, He J, Ezerskiy LA, Wesselschmidt R, Coscia CJ, Belcheva MM. Mu and kappa opioids modulate mouse embryonic stem cell-derived neural progenitor differentiation via MAP kinases. Journal of Neurochemistry. 112: 1431-41. PMID 19895666 DOI: 10.1111/j.1471-4159.2009.06479.x  0.612
2009 Miyatake M, Rubinstein TJ, McLennan GP, Belcheva MM, Coscia CJ. Inhibition of EGF-induced ERK/MAP kinase-mediated astrocyte proliferation by mu opioids: integration of G protein and beta-arrestin 2-dependent pathways. Journal of Neurochemistry. 110: 662-74. PMID 19457093 DOI: 10.1111/j.1471-4159.2009.06156.x  0.63
2008 McLennan GP, Kiss A, Miyatake M, Belcheva MM, Chambers KT, Pozek JJ, Mohabbat Y, Moyer RA, Bohn LM, Coscia CJ. Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways. Journal of Neurochemistry. 107: 1753-65. PMID 19014370 DOI: 10.1111/J.1471-4159.2008.05745.X  0.724
2006 Kim E, Clark AL, Kiss A, Hahn JW, Wesselschmidt R, Coscia CJ, Belcheva MM. Mu- and kappa-opioids induce the differentiation of embryonic stem cells to neural progenitors. The Journal of Biological Chemistry. 281: 33749-60. PMID 16954126 DOI: 10.1074/jbc.M603862200  0.626
2006 Hou Y, Belcheva MM, Clark AL, Zahm DS, Coscia CJ. Increased opioid receptor binding and G protein coupling in the accumbens and ventral tegmental area of postnatal day 2 rats. Neuroscience Letters. 395: 244-8. PMID 16300888 DOI: 10.1016/J.Neulet.2005.10.086  0.598
2005 Belcheva MM, Clark AL, Haas PD, Serna JS, Hahn JW, Kiss A, Coscia CJ. Mu and kappa opioid receptors activate ERK/MAPK via different protein kinase C isoforms and secondary messengers in astrocytes. The Journal of Biological Chemistry. 280: 27662-9. PMID 15944153 DOI: 10.1074/jbc.M502593200  0.633
2004 Hou Y, Tan Y, Belcheva MM, Clark AL, Zahm DS, Coscia CJ. Differential effects of gestational buprenorphine, naloxone, and methadone on mesolimbic mu opioid and ORL1 receptor G protein coupling. Brain Research. Developmental Brain Research. 151: 149-57. PMID 15246701 DOI: 10.1016/J.Devbrainres.2004.05.002  0.637
2003 Belcheva MM, Tan Y, Heaton VM, Clark AL, Coscia CJ. Mu opioid transactivation and down-regulation of the epidermal growth factor receptor in astrocytes: implications for mitogen-activated protein kinase signaling. Molecular Pharmacology. 64: 1391-401. PMID 14645669 DOI: 10.1124/mol.64.6.1391  0.592
2002 Belcheva MM, Haas PD, Tan Y, Heaton VM, Coscia CJ. The fibroblast growth factor receptor is at the site of convergence between mu-opioid receptor and growth factor signaling pathways in rat C6 glioma cells. The Journal of Pharmacology and Experimental Therapeutics. 303: 909-18. PMID 12438509 DOI: 10.1124/jpet.102.038554  0.616
2002 Fábián G, Bozó B, Szikszay M, Horváth G, Coscia CJ, Szücs M. Chronic morphine-induced changes in mu-opioid receptors and G proteins of different subcellular loci in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 302: 774-80. PMID 12130743 DOI: 10.1124/jpet.102.036152  0.651
2002 Belcheva MM, Coscia CJ. Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase. Neuro-Signals. 11: 34-44. PMID 11943881 DOI: 10.1159/000057320  0.561
2001 Belcheva MM, Szùcs M, Wang D, Sadee W, Coscia CJ. mu-Opioid receptor-mediated ERK activation involves calmodulin-dependent epidermal growth factor receptor transactivation. The Journal of Biological Chemistry. 276: 33847-53. PMID 11457825 DOI: 10.1074/jbc.M101535200  0.613
2000 Belcheva MM, Wong YH, Coscia CJ. Evidence for transduction of mu but not kappa opioid modulation of extracellular signal-regulated kinase activity by G(z) and G(12) proteins. Cellular Signalling. 12: 481-9. PMID 10989284 DOI: 10.1016/S0898-6568(00)00095-4  0.614
2000 Bohn LM, Belcheva MM, Coscia CJ. Mu-opioid agonist inhibition of kappa-opioid receptor-stimulated extracellular signal-regulated kinase phosphorylation is dynamin-dependent in C6 glioma cells. Journal of Neurochemistry. 74: 574-81. PMID 10646508 DOI: 10.1046/J.1471-4159.2000.740574.X  0.753
2000 Bohn LM, Belcheva MM, Coscia CJ. Mitogenic signaling via endogenous kappa-opioid receptors in C6 glioma cells: evidence for the involvement of protein kinase C and the mitogen-activated protein kinase signaling cascade. Journal of Neurochemistry. 74: 564-73. PMID 10646507 DOI: 10.1046/J.1471-4159.2000.740564.X  0.726
1999 Ignatova EG, Belcheva MM, Bohn LM, Neuman MC, Coscia CJ. Requirement of receptor internalization for opioid stimulation of mitogen-activated protein kinase: biochemical and immunofluorescence confocal microscopic evidence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 56-63. PMID 9870938 DOI: 10.1523/Jneurosci.19-01-00056.1999  0.751
1998 Pan EC, Bohn LM, Belcheva MM, Thomas GE, Manepalli AN, Mamone JY, Johnson FE, Coscia CJ. Kappa-opioid receptor binding varies inversely with tumor grade in human gliomas. Cancer. 83: 2561-6. PMID 9874464 DOI: 10.1002/(SICI)1097-0142(19981215)83:12<2561::AID-CNCR23>3.0.CO;2-H  0.762
1998 Belcheva MM, Bohn LM, Ho MT, Johnson FE, Yanai J, Barron S, Coscia CJ. Brain opioid receptor adaptation and expression after prenatal exposure to buprenorphine. Brain Research. Developmental Brain Research. 111: 35-42. PMID 9804882 DOI: 10.1016/S0165-3806(98)00117-5  0.766
1998 Bohn LM, Belcheva MM, Coscia CJ. Evidence for kappa- and mu-opioid receptor expression in C6 glioma cells. Journal of Neurochemistry. 70: 1819-25. PMID 9572265 DOI: 10.1046/J.1471-4159.1998.70051819.X  0.762
1998 Belcheva MM, Vogel Z, Ignatova E, Avidor-Reiss T, Zippel R, Levy R, Young EC, Barg J, Coscia CJ. Opioid modulation of extracellular signal-regulated protein kinase activity is ras-dependent and involves Gbetagamma subunits. Journal of Neurochemistry. 70: 635-45. PMID 9453557 DOI: 10.1046/J.1471-4159.1998.70020635.X  0.651
1997 Tencheva ZS, Belcheva MM, Velichkova AA, Lissichkova EG, Coscia CJ. Opioid regulation of AP-1 DNA-binding activity in NG108-15 cells under conditions of opioid-receptor adaptation. Brain Research. Molecular Brain Research. 48: 156-8. PMID 9379837 DOI: 10.1016/S0169-328X(97)00128-9  0.638
1997 Ignatov A, Neuman MC, Barg R, Krueger RJ, Coscia CJ. Immunoblot analyses of the elicited Sanguinaria canadensis enzyme, dihydrobenzophenanthridine oxidase: evidence for resolution from a polyphenol oxidase isozyme. Archives of Biochemistry and Biophysics. 347: 208-12. PMID 9367526 DOI: 10.1006/abbi.1997.0336  0.515
1996 Ignatov A, Clark WG, Cline SD, Psenak M, Krueger J, Coscia CJ. Elicitation of dihydrobenzophenanthridine oxidase in Sanguinaria canadensis cell cultures. Phytochemistry. 43: 1141-4. PMID 8987906 DOI: 10.1016/S0031-9422(96)00540-7  0.538
1996 Belcheva MM, Ignatova EG, Young EC, Coscia CJ. Agonist-induced desensitization and down-regulation of delta opioid receptors alter the levels of their 125I-beta-endorphin cross-linked products in subcellular fractions from NG108-15 cells. Biochemistry. 35: 14818-24. PMID 8942644 DOI: 10.1021/bi961579+  0.603
1996 Belcheva MM, Ho MT, Ignatova EG, Jefcoat LB, Barg J, Vogel Z, McHale RJ, Johnson FE, Coscia CJ. Buprenorphine differentially alters opioid receptor adaptation in rat brain regions. The Journal of Pharmacology and Experimental Therapeutics. 277: 1322-7. PMID 8667193  0.653
1995 Belcheva MM, Gucker S, Chuang DM, Clark WG, Jefcoat LB, McHale RJ, Toth G, Borsodi A, Coscia CJ. Modulation of opioid binding associated with nuclear matrix and nuclear membranes of NG108-15 cells. The Journal of Pharmacology and Experimental Therapeutics. 274: 1513-23. PMID 7562528  0.614
1995 Gorodinsky A, Barg J, Belcheva MM, Levy R, McHale RJ, Vogel Z, Coscia CJ. Dynorphins modulate DNA synthesis in fetal brain cell aggregates. Journal of Neurochemistry. 65: 1481-6. PMID 7561841 DOI: 10.1046/J.1471-4159.1995.65041481.X  0.617
1994 Barg J, Belcheva MM, Levy R, McHale RJ, McLachlan JA, Johnson FE, Coscia CJ, Vogel Z. A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA. Glia. 10: 10-5. PMID 8300189 DOI: 10.1002/Glia.440100103  0.65
1994 Belcheva MM, Dawn S, Barg J, McHale RJ, Ho MT, Ignatova E, Coscia CJ. Transient down-regulation of neonatal rat brain mu-opioid receptors upon in utero exposure to buprenorphine. Brain Research. Developmental Brain Research. 80: 158-62. PMID 7955341 DOI: 10.1016/0165-3806(94)90100-7  0.642
1994 Belcheva MM, Barg J, Mchale R, Coscia CJ. Naltrexone induces down- and upregulation of delta opioid receptors in rat brain regions. Brain Research Bulletin. 35: 69-72. PMID 7953760 DOI: 10.1016/0361-9230(94)90218-6  0.662
1994 Barg J, Belcheva MM, Zimlichman R, Levy R, Saya D, McHale RJ, Johnson FE, Coscia CJ, Vogel Z. Opioids inhibit endothelin-mediated DNA synthesis, phosphoinositide turnover, and Ca2+ mobilization in rat C6 glioma cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 5858-64. PMID 7931548  0.636
1994 Belcheva M, McHale R, Toth G, Borsodi A, Coscia C. Nuclear matrix associated opioid binding sites are increased upon D-Ala2-D-Leu5-enkephalin-induced down-regulation in NG108-15 cells Regulatory Peptides. 54: 21-22. DOI: 10.1016/0167-0115(94)90369-7  0.667
1993 Belcheva M, Barg J, Rowinski J, Clark WG, Gloeckner CA, Ho A, Gao XM, Chuang DM, Coscia C. Novel opioid binding sites associated with nuclei of NG108-15 neurohybrid cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 104-14. PMID 8423466 DOI: 10.1523/Jneurosci.13-01-00104.1993  0.68
1993 Belcheva MM, Barg J, McHale RJ, Dawn S, Ho MT, Ignatova E, Coscia CJ. Differential down- and up-regulation of rat brain opioid receptor types and subtypes by buprenorphine. Molecular Pharmacology. 44: 173-9. PMID 8393519  0.663
1993 Barg J, Belcheva MM, RowiÅ„ski J, Coscia CJ. kappa-Opioid agonist modulation of [3H]thymidine incorporation into DNA: evidence for the involvement of pertussis toxin-sensitive G protein-coupled phosphoinositide turnover. Journal of Neurochemistry. 60: 1505-11. PMID 8384252 DOI: 10.1111/J.1471-4159.1993.Tb03314.X  0.627
1993 Barg J, Belcheva M, McHale R, Levy R, Vogel Z, Coscia CJ. Beta-endorphin is a potent inhibitor of thymidine incorporation into DNA via mu- and kappa-opioid receptors in fetal rat brain cell aggregates in culture. Journal of Neurochemistry. 60: 765-7. PMID 8380443 DOI: 10.1111/J.1471-4159.1993.Tb03214.X  0.595
1993 Cline SD, McHale RJ, Coscia CJ. Differential enhancement of benzophenanthridine alkaloid content in cell suspension cultures of Sanguinaria canadensis under conditions of combined hormonal deprivation and fungal elicitation. Journal of Natural Products. 56: 1219-28. PMID 8229008 DOI: 10.1021/Np50098A003  0.519
1993 Barg J, Belcheva M, Rowinski J, Ho A, Burke WJ, Chung HD, Schmidt CA, Coscia CJ. Opioid receptor density changes in Alzheimer amygdala and putamen. Brain Research. 632: 209-15. PMID 8149229 DOI: 10.1016/0006-8993(93)91155-L  0.641
1992 Arakawa H, Clark WG, Psenak M, Coscia CJ. Purification and characterization of dihydrobenzophenanthridine oxidase from elicited Sanguinaria canadensis cell cultures. Archives of Biochemistry and Biophysics. 299: 1-7. PMID 1444440 DOI: 10.1016/0003-9861(92)90236-P  0.528
1992 Belcheva MM, Barg J, Gloeckner C, Gao XM, Chuang DM, Coscia CJ. Antagonist-induced transient down-regulation of delta-opioid receptors in NG108-15 cells. Molecular Pharmacology. 42: 445-52. PMID 1328845  0.668
1992 Barg J, Belcheva MM, Coscia CJ. Evidence for the implication of phosphoinositol signal transduction in mu-opioid inhibition of DNA synthesis. Journal of Neurochemistry. 59: 1145-52. PMID 1322969 DOI: 10.1111/J.1471-4159.1992.Tb08357.X  0.638
1992 Szücs M, Coscia CJ. Differential coupling of opioid binding sites to guanosine triphosphate binding regulatory proteins in subcellular fractions of rat brain. Journal of Neuroscience Research. 31: 565-72. PMID 1322465 DOI: 10.1002/jnr.490310322  0.662
1992 Barg J, Rius RA, Bem WT, Belcheva MM, Loh YP, Coscia CJ. Differential development of beta-endorphin and mu opioid binding sites in mouse brain. Brain Research. Developmental Brain Research. 66: 71-6. PMID 1318173 DOI: 10.1016/0165-3806(92)90142-J  0.644
1991 Rius RA, Barg J, Bem WT, Coscia CJ, Loh YP. The prenatal development profile of expression of opioid peptides and receptors in the mouse brain. Brain Research. Developmental Brain Research. 58: 237-41. PMID 1674235 DOI: 10.1016/0165-3806(91)90010-G  0.624
1991 Arakawa H, Mueller KJ, Doubek WG, Stern JA, La Regina MC, Tolman KC, Coscia CJ, Johnson FE. Distribution and metabolism of doxorubicin in rats undergoing testicular circulatory isolation. American Journal of Surgery. 162: 572-5. PMID 1670227 DOI: 10.1016/0002-9610(91)90111-P  0.489
1991 Barg J, Belcheva MM, Bem WT, Lambourne B, McLachlan JA, Tolman KC, Johnson FE, Coscia CJ. Desipramine modulation of sigma and opioid peptide receptor expression in glial cells. Peptides. 12: 845-9. PMID 1664948 DOI: 10.1016/0196-9781(91)90144-E  0.653
1991 Loh YP, Rius RA, Elkabes S, Bem W, Coscia CJ. Prenatal expression of pro-opiomelanocortin mRNA, POMC-derived peptides, and mu-opiate receptors in the mouse embryo. Nida Research Monograph. 111: 96-112. PMID 1663583  0.537
1991 Bem WT, Thomas GE, Mamone JY, Homan SM, Levy BK, Johnson FE, Coscia CJ. Overexpression of sigma receptors in nonneural human tumors. Cancer Research. 51: 6558-62. PMID 1660342  0.627
1991 Belcheva MM, Barg J, McHale RJ, Gao XM, Chuang DM, Coscia CJ. Up-regulation of delta opioid receptors in neuroblastoma hybrid cells: evidence for differences in the mechanisms of action of sodium butyrate and naltrexone. The Journal of Pharmacology and Experimental Therapeutics. 259: 302-9. PMID 1656025  0.671
1991 Bem WT, Yeung SJ, Belcheva M, Barg J, Coscia CJ. Age-dependent changes in the subcellular distribution of rat brain mu-opioid receptors and GTP binding regulatory proteins. Journal of Neurochemistry. 57: 1470-7. PMID 1655974 DOI: 10.1111/J.1471-4159.1991.Tb06340.X  0.642
1991 Coscia CJ, Szücs M, Barg J, Belcheva MM, Bem WT, Khoobehi K, Donnigan TA, Juszczak R, McHale RJ, Hanley MR. A monoclonal anti-idiotypic antibody to mu and delta opioid receptors. Brain Research. Molecular Brain Research. 9: 299-306. PMID 1645433 DOI: 10.1016/0169-328X(91)90076-A  0.653
1990 Szücs M, Coscia CJ. Evidence for delta-opioid binding and GTP-regulatory proteins in 5-day-old rat brain membranes. Journal of Neurochemistry. 54: 1419-25. PMID 2156021 DOI: 10.1111/j.1471-4159.1990.tb01978.x  0.619
1990 Coscia CJ, Belcheva M, Gao XM, Chuang DM. Effects of up-regulation by butyrate on delta opioid receptor GTP sensitivity and distribution in subcellular compartments. Progress in Clinical and Biological Research. 328: 157-60. PMID 2154771  0.626
1990 Thomas GE, Szücs M, Mamone JY, Bem WT, Rush MD, Johnson FE, Coscia CJ. Sigma and opioid receptors in human brain tumors. Life Sciences. 46: 1279-86. PMID 1971702 DOI: 10.1016/0024-3205(90)90360-4  0.617
1989 Cline SD, Coscia CJ. Ultrastructural changes associated with the accumulation and secretion of sanguinarine in Papaver bracteatum suspension cultures treated with fungal elicitor. Planta. 178: 303-14. PMID 24212897 DOI: 10.1007/BF00391858  0.51
1989 Moudy AM, Coscia CJ, Laskowski MB. A mu-specific opioid peptide agonist increases excitability of pyramidal neurons in untreated and receptor up-regulated hippocampus. The Journal of Pharmacology and Experimental Therapeutics. 251: 536-42. PMID 2553926  0.64
1989 McLean S, Rothman RB, Chuang DM, Rice KC, Spain JW, Coscia CJ, Roth BL. Cross-linking of [125I]beta-endorphin to mu-opioid receptors during development. Brain Research. Developmental Brain Research. 45: 283-9. PMID 2540924 DOI: 10.1016/0165-3806(89)90046-1  0.691
1988 Cline SD, Coscia CJ. Stimulation of Sanguinarine Production by Combined Fungal Elicitation and Hormonal Deprivation in Cell Suspension Cultures of Papaver bracteatum. Plant Physiology. 86: 161-5. PMID 16665861 DOI: 10.1104/Pp.86.1.161  0.518
1988 Spain JW, Petta DE, Coscia CJ. Binding kinetics of delta opioid receptors differ for microsomal and synaptic sites. Molecular Pharmacology. 34: 23-8. PMID 2839762  0.609
1987 Roberts MF, Kutchan TM, Brown RT, Coscia CJ. Implication of tyramine in the biosynthesis of morphinan alkaloids in Papaver. Planta. 172: 230-7. PMID 24225875 DOI: 10.1007/BF00394592  0.531
1987 Spain JW, Coscia CJ. Multiple interconvertible affinity states for the delta opioid agonist-receptor complex. The Journal of Biological Chemistry. 262: 8948-51. PMID 3036838  0.585
1987 Johnson FE, Hudd C, LaRegina MC, Beinfeld MC, Tolbert DL, Spain JW, Szucs M, Coscia CJ. Exogenous cholecystokinin (CCK) reduces neonatal rat brain opioid receptor density and CCK levels. Brain Research. 429: 139-46. PMID 3032370 DOI: 10.1016/0165-3806(87)90147-7  0.611
1987 Oetting GM, Szücs M, Coscia CJ. Differential ontogeny of divalent cation effects on rat brain delta-, mu-, and kappa-opioid receptor binding. Brain Research. 428: 223-7. PMID 3030506 DOI: 10.1016/0165-3806(87)90120-9  0.636
1987 Szücs M, Spain JW, Oetting GM, Moudy AM, Coscia CJ. Guanine nucleotide and cation regulation of mu, delta, and kappa opioid receptor binding: evidence for differential postnatal development in rat brain. Journal of Neurochemistry. 48: 1165-70. PMID 3029328 DOI: 10.1111/j.1471-4159.1987.tb05642.x  0.64
1986 Kutchan TM, Rush M, Coscia CJ. Subcellular Localization of Alkaloids and Dopamine in Different Vacuolar Compartments of Papaver bracteatum. Plant Physiology. 81: 161-6. PMID 16664767 DOI: 10.1104/Pp.81.1.161  0.505
1986 Chuang DM, Dillon-Carter O, Spain JW, Laskowski MB, Roth BL, Coscia CJ. Detection and characterization of beta-adrenergic receptors and adenylate cyclase in coated vesicles isolated from bovine brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 2578-84. PMID 3018196 DOI: 10.1523/Jneurosci.06-09-02578.1986  0.681
1986 Devane WA, Spain JW, Coscia CJ, Howlett AC. An assessment of the role of opioid receptors in the response to cannabimimetic drugs. Journal of Neurochemistry. 46: 1929-35. PMID 3009717 DOI: 10.1111/J.1471-4159.1986.Tb08515.X  0.634
1986 Szücs M, Oetting GM, Coscia CJ. Multiple sites of divalent cation modulation of delta opioid receptor binding. Nida Research Monograph. 75: 113-6. PMID 2828955  0.612
1986 Spain JW, Petta DE, Coscia CJ. A comparison of microsomal and synaptic delta site binding kinetics. Nida Research Monograph. 75: 109-12. PMID 2828954  0.572
1985 Rush MD, Kutchan TM, Coscia CJ. Correlation of the appearance of morphinan alkaloids and laticifer cells in germinating Papaver bracteatum seedlings. Plant Cell Reports. 4: 237-40. PMID 24253977 DOI: 10.1007/BF00269366  0.511
1985 Daw NW, Videen TO, Rader RK, Robertson TW, Coscia CJ. Substantial reduction of noradrenaline in kitten visual cortex by intraventricular injections of 6-hydroxydopamine does not always prevent ocular dominance shifts after monocular deprivation. Experimental Brain Research. 59: 30-5. PMID 3926529 DOI: 10.1007/BF00237662  0.463
1985 Moudy AM, Spain JW, Coscia CJ. Differential up-regulation of microsomal and synaptic membrane mu opioid receptors. Biochemical and Biophysical Research Communications. 132: 735-41. PMID 2998381 DOI: 10.1016/0006-291X(85)91194-5  0.648
1985 Spain JW, Roth BL, Coscia CJ. Differential ontogeny of multiple opioid receptors (mu, delta, and kappa). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 584-8. PMID 2983043 DOI: 10.1523/Jneurosci.05-03-00584.1985  0.71
1985 Bennett DB, Spain JW, Laskowski MB, Roth BL, Coscia CJ. Stereospecific opiate-binding sites occur in coated vesicles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 3010-5. PMID 2865342 DOI: 10.1523/Jneurosci.05-11-03010.1985  0.659
1984 Daw NW, Robertson TW, Rader RK, Videen TO, Coscia CJ. Substantial reduction of cortical noradrenaline by lesions of adrenergic pathway does not prevent effects of monocular deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 1354-60. PMID 6427422 DOI: 10.1523/Jneurosci.04-05-01354.1984  0.466
1984 Roth BL, Coscia CJ. Microsomal opiate receptors: characterization of smooth microsomal and synaptic membrane opiate receptors. Journal of Neurochemistry. 42: 1677-84. PMID 6327910 DOI: 10.1111/J.1471-4159.1984.Tb12759.X  0.68
1984 Spain JW, Bennett DB, Coscia CJ. Gpp(NH)p promotes the formation of a low affinity state for the delta opioid agonist-receptor complex. Neuropeptides. 5: 145-8. PMID 6099484 DOI: 10.1016/0143-4179(84)90048-9  0.614
1984 Scheibe SD, Bennett DB, Spain JW, Roth BL, Coscia CJ. Kinetic evidence for differential agonist and antagonist binding to bovine hippocampal synaptic membrane opioid receptors. The Journal of Biological Chemistry. 259: 13298-303. PMID 6092373  0.702
1983 Kutchan TM, Ayabe S, Krueger RJ, Coscia EM, Coscia CJ. Cytodifferentiation and alkaloid accumulation in cultured cells of Papaver bracteatum. Plant Cell Reports. 2: 281-4. PMID 24258185 DOI: 10.1007/BF00270181  0.502
1983 Roberts MF, McCarthy D, Kutchan TM, Coscia CJ. Localization of enzymes and alkaloidal metabolites in Papaver latex. Archives of Biochemistry and Biophysics. 222: 599-609. PMID 6847205 DOI: 10.1016/0003-9861(83)90558-1  0.558
1983 Bennett DB, Coscia CJ. Differential inhibition of activated tyrosine hydroxylase. Archives of Biochemistry and Biophysics. 227: 562-9. PMID 6141765 DOI: 10.1016/0003-9861(83)90485-X  0.56
1983 Spain JW, Bennett DB, Roth BL, Coscia CJ. Ontogeny of benzomorphan-selective (kappa) sites: a computerized analysis. Life Sciences. 33: 235-8. PMID 6141487 DOI: 10.1016/0024-3205(83)90486-1  0.662
1982 Burke WJ, Galloway MP, Coscia CJ. Tetrahydroisoquinolinecarboxylic acids and regulation of phenylethanolamine N-methyltransferase in cultured adrenal medulla. Biochemical Pharmacology. 31: 3257-60. PMID 7150354 DOI: 10.1016/0006-2952(82)90559-7  0.68
1982 Galloway MP, Burke WJ, Coscia CJ. Tetrahydroisoquinolinecarboxylic acids and catecholamine metabolism in adrenal medulla explants. Biochemical Pharmacology. 31: 3251-6. PMID 7150353 DOI: 10.1016/0006-2952(82)90558-5  0.687
1982 Spitsberg VL, Coscia CJ. Quinone reductases of higher plants. European Journal of Biochemistry / Febs. 127: 67-70. PMID 7140760 DOI: 10.1111/J.1432-1033.1982.Tb06838.X  0.501
1982 Roth BL, Laskowski MB, Coscia CJ. Microsomal opiate receptors differ from synaptic membrane receptors in proteolytic sensitivity. Brain Research. 250: 101-9. PMID 6291719 DOI: 10.1016/0006-8993(82)90956-8  0.647
1982 Pryhuber KG, Roth BL, Coscia CJ. Demonstration of a slowly dissociating form of bovine hippocampal synaptic membrane opiate receptors. European Journal of Pharmacology. 83: 47-53. PMID 6290246 DOI: 10.1016/0014-2999(82)90284-9  0.682
1982 Wohltmann M, Roth BL, Coscia CJ. Differential postnatal development of mu and delta opiate receptors. Brain Research. 255: 679-84. PMID 6280810 DOI: 10.1016/0165-3806(82)90066-9  0.695
1982 Bennett DB, Galloway MP, Coscia CJ. Interaction of tetrahydroisoquinolines with activated tyrosine hydroxylase. Progress in Clinical and Biological Research. 90: 301-9. PMID 6125949  0.649
1981 Spitsberg V, Coscia CJ, Krueger RJ. Characterization of a monoterpene hydroxylase from cell suspension cultures of Catharanthus roseus (L.) G. Don. Plant Cell Reports. 1: 43-7. PMID 24258855 DOI: 10.1007/BF00269268  0.526
1981 Roth BL, Laskowski MB, Coscia CJ. Evidence for distinct subcellular sites of opiate receptors. Demonstration of opiate receptors in smooth microsomal fractions isolated from rat brain. The Journal of Biological Chemistry. 256: 10017-23. PMID 6268622  0.664
1981 Galloway MP, Roth BL, Coscia CJ. The effects of tetrahydroisoquinolinecarboxylic acids in tyrosine 3-monooxygenase. Archives of Biochemistry and Biophysics. 209: 620-7. PMID 6117253 DOI: 10.1016/0003-9861(81)90321-0  0.711
1980 Roth BL, Galloway MP, Coscia CJ. The effects of morphine on catecholamine metabolism during postnatal development. Brain Research. 197: 561-4. PMID 7407575 DOI: 10.1016/0006-8993(80)91147-6  0.734
1980 Lasala JM, Cicero TJ, Coscia CJ. Opiate-like effects of norlaudanosolinecarboxylic acids on the hypothalamic-pituitary-gonadal axis. Biochemical Pharmacology. 29: 57-61. PMID 6244829 DOI: 10.1016/0006-2952(80)90244-0  0.546
1980 Coscia CJ, Burke WJ, Galloway MP, Kosloff AH, Lasala JM, McFarlane J, Mitchell JS, O'Toole MM, Roth BL. Effects of norlaudanosolinecarboxylic acids on enzymes of catecholamine metabolism. The Journal of Pharmacology and Experimental Therapeutics. 212: 91-6. PMID 6101345  0.718
1979 Lasala JM, Coscia CJ. Accumulation of a tetrahydroisoquinoline in phenylketonuria. Science (New York, N.Y.). 203: 283-4. PMID 153583 DOI: 10.1126/Science.153583  0.52
1979 Madyastha KM, Coscia CJ. Detergent-solubilized NADPH-cytochrome c(P-450) reductase from the higher plant, Catharanthus roseus. Purification and characterization. The Journal of Biological Chemistry. 254: 2419-27. PMID 107158  0.489
1978 Licht HJ, Coscia CJ. Cytochrome P-450LM2 mediated hydroxylation of monoterpene alcohols. Biochemistry. 17: 5638-46. PMID 728422 DOI: 10.1021/Bi00619A009  0.466
1978 Mitchell J, Coscia CJ. Application of paired-ion high-pressure liquid column chromatography to the analysis of L-3,4-dihydroxyphenylalanine metabolites. Journal of Chromatography. 145: 295-301. PMID 649723 DOI: 10.1016/S0378-4347(00)81351-1  0.458
1977 Coscia CJ, Burke W, Jamroz G, Lasala JM, McFarlane J, Mitchell J, O'Toole MM, Wilson ML. Occurrence of a new class of tetrahydroisoquinoline alkaloids in L-dopa-treated parkinsonian patients. Nature. 269: 617-9. PMID 917111 DOI: 10.1038/269617a0  0.483
1977 Madyastha KM, Ridgway JE, Dwyer JG, Coscia CJ. Subcellular localization of a cytochrome P-450-dependent monogenase in vesicles of the higher plant Catharanthus roseus. The Journal of Cell Biology. 72: 302-13. PMID 833200  0.528
1976 Madyastha KM, Meehan TD, Coscia CJ. Characterization of a cytochrome P-450 dependent monoterpene hydroxylase from the higher plant Vinca rosea. Biochemistry. 15: 1097-102. PMID 3209 DOI: 10.1021/Bi00650A023  0.531
1975 McFarlane J, Madyastha KM, Coscia CJ. Regulation of secondary metabolism in higher plants. Effect of alkaloids on a cytochrome P-450 dependent monooxygenase. Biochemical and Biophysical Research Communications. 66: 1263-9. PMID 1191293 DOI: 10.1016/0006-291X(75)90495-7  0.544
1975 Wilson ML, Coscia CJ. Studies on the early stages of Papaver alkaloid biogenesis. Journal of the American Chemical Society. 97: 431-2. PMID 1133361  0.443
1973 Baxter C, Coscia CJ. In vitro synthesis of spermidine in the higher plant, Vinca rosea. Biochemical and Biophysical Research Communications. 54: 147-54. PMID 4741562 DOI: 10.1016/0006-291X(73)90901-7  0.507
1973 Madyastha KM, Guarnaccia R, Baxter C, Coscia CJ. S-Adenosyl-L-methionine: loganic acid methyltransferase. A carboxyl-alkylating enzyme from Vinca rosea. The Journal of Biological Chemistry. 248: 2497-501. PMID 4698228  0.486
1973 Meehan TD, Coscia CJ. Hydroxylation of geraniol and nerol by a monooxygenase from Vinca rosea. Biochemical and Biophysical Research Communications. 53: 1043-8. PMID 4147883 DOI: 10.1016/0006-291X(73)90570-6  0.528
1972 Madyastha KM, Guarnaccia R, Coscia CJ. Carboxyl group methylation of loganic acid by a cell-free enzyme preparation from Vinca rosea. The Biochemical Journal. 128: 34P. PMID 4404427 DOI: 10.1042/Bj1280034P  0.499
1971 Madyastha KM, Guarnaccia R, Coscia CJ. Enzymic synthesis of loganin by carboxyl group methylation of loganic acid. Febs Letters. 14: 175-177. PMID 11945749 DOI: 10.1016/0014-5793(71)80097-2  0.488
1970 Coscia CJ, Botta L, Guarnaccia R. On the mechanism of iridoid and secoiridoid monoterpene biosynthesis. Archives of Biochemistry and Biophysics. 136: 498-506. PMID 5435439 DOI: 10.1016/0003-9861(70)90221-3  0.485
1969 Coscia CJ, Guarnaccia R, Botta L. Monoterpene biosynthesis. I. Occurrence and mevalonoid origin of gentiopicroside and loganic acid in Swertia caroliniensis. Biochemistry. 8: 5036-43. PMID 5365793  0.477
1967 Coscia CJ, Guarnaccia R. Biosynthesis of gentiopicroside, a novel monoterpene. Journal of the American Chemical Society. 89: 1280-1. PMID 6041352  0.475
1967 Campbell IM, Coscia CJ, Kelsey M, Bentley R. Origin of the aromatic nucleus in bacterial menaquinones. Biochemical and Biophysical Research Communications. 28: 25-9. PMID 4860629  0.467
1962 COSCIA CJ, RAMIREZ MI, SCHUBERT WJ, NORD FF. Investigations on lignins and lignification. XXVI. Studies on the utilization of pyruvate in lignification. Biochemistry. 1: 447-51. PMID 13881532  0.46
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