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Xue Sherry Gao - Publications

Affiliations: 
Chemical Engineering Tianjin University, Tianjin, Tianjin Shi, China 
 2013 Chemical and Biomolecular Engineering University of California, Los Angeles, Los Angeles, CA 
 2013-2017 Chemistry and Chemical Biology Harvard University and the Broad Institute of MIT and Harvard, 
 2017- Chemical and Biomolecular Engineering Rice University, Houston, TX 
Website:
http://gaolab.rice.edu/
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zeng H, Yuan Q, Peng F, Ma D, Lingineni A, Chee K, Gilberd P, Osikpa EC, Sun Z, Gao X. A split and inducible adenine base editor for precise in vivo base editing. Nature Communications. 14: 5573. PMID 37696818 DOI: 10.1038/s41467-023-41331-5  0.41
2023 Tao Y, Lamas V, Du W, Zhu W, Li Y, Whittaker MN, Zuris JA, Thompson DB, Rameshbabu AP, Shu Y, Gao X, Hu JH, Pei C, Kong WJ, Liu X, et al. Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo. Nature Communications. 14: 4928. PMID 37582836 DOI: 10.1038/s41467-023-40476-7  0.365
2023 Ma D, Yuan Q, Peng F, Paredes V, Zeng H, Osikpa EC, Yang Q, Peddi A, Patel A, Liu MS, Sun Z, Gao X. Engineered PROTAC-CID Systems for Mammalian Inducible Gene Regulation. Journal of the American Chemical Society. PMID 36626587 DOI: 10.1021/jacs.2c09129  0.43
2020 Zhao F, Liu Z, Yang S, Ding N, Gao X. Quinolactacin Biosynthesis Involves NRPSs Catalyzed Dieckmann Condensation to Form the Quinolone-γ-lactam Hybrid. Angewandte Chemie (International Ed. in English). PMID 32663343 DOI: 10.1002/Anie.202005770  0.303
2020 Ding N, Lee S, Lieber-Kotz M, Yang J, Gao X. Advances in genome editing for genetic hearing loss. Advanced Drug Delivery Reviews. PMID 32387678 DOI: 10.1016/J.Addr.2020.05.001  0.308
2018 Hu JH, Miller SM, Geurts MH, Tang W, Chen L, Sun N, Zeina CM, Gao X, Rees HA, Lin Z, Liu DR. Evolved Cas9 variants with broad PAM compatibility and high DNA specificity. Nature. PMID 29512652 DOI: 10.1038/Nature26155  0.447
2017 Gao X, Tao Y, Lamas V, Huang M, Yeh WH, Pan B, Hu YJ, Hu JH, Thompson DB, Shu Y, Li Y, Wang H, Yang S, Xu Q, Polley DB, et al. Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. Nature. PMID 29258297 DOI: 10.1038/Nature25164  0.45
2016 Wang M, Zuris JA, Meng F, Rees H, Sun S, Deng P, Han Y, Gao X, Pouli D, Wu Q, Georgakoudi I, Liu DR, Xu Q. Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929348 DOI: 10.1073/Pnas.1520244113  0.434
2015 Fan H, Wu Y, Zhou X, Xia J, Zhang W, Song Y, Liu F, Chen Y, Zhang L, Gao X, Gao H, Li J. Pathway-Based Genome-Wide Association Studies for Two Meat Production Traits in Simmental Cattle. Scientific Reports. 5: 18389. PMID 26672757 DOI: 10.1038/srep18389  0.325
2014 Jiménez-Osés G, Osuna S, Gao X, Sawaya MR, Gilson L, Collier SJ, Huisman GW, Yeates TO, Tang Y, Houk KN. The role of distant mutations and allosteric regulation on LovD active site dynamics. Nature Chemical Biology. 10: 431-6. PMID 24727900 DOI: 10.1038/Nchembio.1503  0.474
2013 Gao X, Jiang W, Jiménez-Osés G, Choi MS, Houk KN, Tang Y, Walsh CT. An iterative, bimodular nonribosomal peptide synthetase that converts anthranilate and tryptophan into tetracyclic asperlicins. Chemistry & Biology. 20: 870-8. PMID 23890005 DOI: 10.1016/J.Chembiol.2013.04.019  0.45
2013 Walsh CT, Haynes SW, Ames BD, Gao X, Tang Y. Short pathways to complexity generation: fungal peptidyl alkaloid multicyclic scaffolds from anthranilate building blocks. Acs Chemical Biology. 8: 1366-82. PMID 23659680 DOI: 10.1021/Cb4001684  0.412
2013 Wang P, Bashiri G, Gao X, Sawaya MR, Tang Y. Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis. Journal of the American Chemical Society. 135: 7138-41. PMID 23621493 DOI: 10.1021/Ja403516U  0.437
2013 Haynes SW, Gao X, Tang Y, Walsh CT. Complexity generation in fungal peptidyl alkaloid biosynthesis: a two-enzyme pathway to the hexacyclic MDR export pump inhibitor ardeemin. Acs Chemical Biology. 8: 741-8. PMID 23330675 DOI: 10.1021/Cb3006787  0.502
2012 Haynes SW, Gao X, Tang Y, Walsh CT. Assembly of asperlicin peptidyl alkaloids from anthranilate and tryptophan: a two-enzyme pathway generates heptacyclic scaffold complexity in asperlicin E. Journal of the American Chemical Society. 134: 17444-7. PMID 23030663 DOI: 10.1021/Ja308371Z  0.482
2012 Wang P, Kim W, Pickens LB, Gao X, Tang Y. Heterologous expression and manipulation of three tetracycline biosynthetic pathways. Angewandte Chemie (International Ed. in English). 51: 11136-40. PMID 23024027 DOI: 10.1002/Anie.201205426  0.666
2012 Gao X, Haynes SW, Ames BD, Wang P, Vien LP, Walsh CT, Tang Y. Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain. Nature Chemical Biology. 8: 823-30. PMID 22902615 DOI: 10.1038/Nchembio.1047  0.401
2012 Wang P, Gao X, Tang Y. Complexity generation during natural product biosynthesis using redox enzymes. Current Opinion in Chemical Biology. 16: 362-9. PMID 22564679 DOI: 10.1016/J.Cbpa.2012.04.008  0.471
2011 Ames BD, Haynes SW, Gao X, Evans BS, Kelleher NL, Tang Y, Walsh CT. Complexity generation in fungal peptidyl alkaloid biosynthesis: oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from Aspergillus fumigatus. Biochemistry. 50: 8756-69. PMID 21899262 DOI: 10.1021/Bi201302W  0.464
2011 Wang P, Gao X, Chooi YH, Deng Z, Tang Y. Genetic characterization of enzymes involved in the priming steps of oxytetracycline biosynthesis in Streptomyces rimosus. Microbiology (Reading, England). 157: 2401-9. PMID 21622525 DOI: 10.1099/Mic.0.048439-0  0.659
2011 Haynes SW, Ames BD, Gao X, Tang Y, Walsh CT. Unraveling terminal C-domain-mediated condensation in fungal biosynthesis of imidazoindolone metabolites. Biochemistry. 50: 5668-79. PMID 21591693 DOI: 10.1021/Bi2004922  0.424
2011 Gao X, Chooi YH, Ames BD, Wang P, Walsh CT, Tang Y. Fungal indole alkaloid biosynthesis: genetic and biochemical investigation of the tryptoquialanine pathway in Penicillium aethiopicum. Journal of the American Chemical Society. 133: 2729-41. PMID 21299212 DOI: 10.1021/Ja1101085  0.676
2010 Gao X, Wang P, Tang Y. Engineered polyketide biosynthesis and biocatalysis in Escherichia coli. Applied Microbiology and Biotechnology. 88: 1233-42. PMID 20853106 DOI: 10.1007/S00253-010-2860-4  0.457
2009 Gao X, Xie X, Pashkov I, Sawaya MR, Laidman J, Zhang W, Cacho R, Yeates TO, Tang Y. Directed evolution and structural characterization of a simvastatin synthase. Chemistry & Biology. 16: 1064-74. PMID 19875080 DOI: 10.1016/J.Chembiol.2009.09.017  0.695
2009 Xie X, Pashkov I, Gao X, Guerrero JL, Yeates TO, Tang Y. Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity. Biotechnology and Bioengineering. 102: 20-8. PMID 18988191 DOI: 10.1002/Bit.22028  0.574
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