Year |
Citation |
Score |
2019 |
Reisdorf WC, Xie Q, Zeng X, Xie W, Rajpal N, Hoang B, Burgert ME, Kumar V, Hurle MR, Rajpal DK, O'Donnell S, MacDonald TT, Vossenkämper A, Wang L, Reilly M, ... ... Agarwal P, et al. Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease. Plos One. 14: e0215033. PMID 31002701 DOI: 10.1371/Journal.Pone.0215033 |
0.661 |
|
2019 |
Jhamb D, Magid-Slav M, Hurle MR, Agarwal P. Pathway analysis of GWAS loci identifies novel drug targets and repurposing opportunities. Drug Discovery Today. PMID 30935985 DOI: 10.1016/J.Drudis.2019.03.024 |
0.384 |
|
2019 |
Yao J, Hurle MR, Nelson MR, Agarwal P. Predicting clinically promising therapeutic hypotheses using tensor factorization. Bmc Bioinformatics. 20: 69. PMID 30736745 DOI: 10.1186/S12859-019-2664-1 |
0.393 |
|
2019 |
Ji X, Freudenberg JM, Agarwal P. Integrating Biological Networks for Drug Target Prediction and Prioritization. Methods in Molecular Biology (Clifton, N.J.). 1903: 203-218. PMID 30547444 DOI: 10.1007/978-1-4939-8955-3_12 |
0.362 |
|
2018 |
Rouillard AD, Hurle MR, Agarwal P. Systematic interrogation of diverse Omic data reveals interpretable, robust, and generalizable transcriptomic features of clinically successful therapeutic targets. Plos Computational Biology. 14: e1006142. PMID 29782487 DOI: 10.1371/Journal.Pcbi.1006142 |
0.334 |
|
2017 |
Khaladkar M, Koscielny G, Hasan S, Agarwal P, Dunham I, Rajpal D, Sanseau P. Uncovering novel repositioning opportunities using the Open Targets platform. Drug Discovery Today. PMID 28919242 DOI: 10.1016/J.Drudis.2017.09.007 |
0.41 |
|
2017 |
Reisdorf WC, Chhugani N, Sanseau P, Agarwal P. Harnessing public domain data to discover and validate therapeutic targets. Expert Opinion On Drug Discovery. 1-7. PMID 28494630 DOI: 10.1080/17460441.2017.1329296 |
0.669 |
|
2016 |
Kumar V, Sanseau P, Simola DF, Hurle MR, Agarwal P. Systematic Analysis of Drug Targets Confirms Expression in Disease-Relevant Tissues. Scientific Reports. 6: 36205. PMID 27824084 DOI: 10.1038/Srep36205 |
0.375 |
|
2014 |
Cheng J, Yang L, Kumar V, Agarwal P. Systematic evaluation of connectivity map for disease indications. Genome Medicine. 6: 540. PMID 25606058 DOI: 10.1186/S13073-014-0095-1 |
0.374 |
|
2014 |
Swamidass SJ, Schillebeeckx CN, Matlock M, Hurle MR, Agarwal P. Combined Analysis of Phenotypic and Target-Based Screening in Assay Networks. Journal of Biomolecular Screening. 19: 782-790. PMID 24563424 DOI: 10.1177/1087057114523068 |
0.321 |
|
2014 |
Liu Y, Platchek M, Kement B, Bee WT, Truong M, Zeng X, Hung S, Lin H, Morrow D, Kallal LA, Xie Q, Agarwal P, Pope AJ, Wu Z. A novel approach applying a chemical biology strategy in phenotypic screening reveals pathway-selective regulators of histone 3 K27 tri-methylation. Molecular Biosystems. 10: 251-7. PMID 24257700 DOI: 10.1039/C3Mb70413K |
0.337 |
|
2013 |
Agarwal P, Sanseau P, Cardon LR. Novelty in the target landscape of the pharmaceutical industry. Nature Reviews. Drug Discovery. 12: 575-6. PMID 23903214 DOI: 10.1038/Nrd4089 |
0.335 |
|
2013 |
Hurle MR, Yang L, Xie Q, Rajpal DK, Sanseau P, Agarwal P. Computational Drug Repositioning: From Data to Therapeutics Clinical Pharmacology & Therapeutics. 93: 335-341. PMID 23443757 DOI: 10.1038/Clpt.2013.1 |
0.36 |
|
2011 |
Yang L, Agarwal P. Systematic drug repositioning based on clinical side-effects. Plos One. 6: e28025. PMID 22205936 DOI: 10.1371/Journal.Pone.0028025 |
0.353 |
|
2011 |
Yao L, Zhang Y, Li Y, Sanseau P, Agarwal P. Electronic health records: Implications for drug discovery. Drug Discovery Today. 16: 594-9. PMID 21624499 DOI: 10.1016/J.Drudis.2011.05.009 |
0.337 |
|
2009 |
Agarwal P, Searls DB. Can literature analysis identify innovation drivers in drug discovery? Nature Reviews. Drug Discovery. 8: 865-78. PMID 19876041 DOI: 10.1038/Nrd2973 |
0.4 |
|
2009 |
Hu G, Agarwal P. Human disease-drug network based on genomic expression profiles. Plos One. 4. PMID 19657382 DOI: 10.1371/Journal.Pone.0006536 |
0.392 |
|
2009 |
Li Y, Agarwal P. A Pathway-Based View of Human Diseases and Disease Relationships Plos One. 4. PMID 19194489 DOI: 10.1371/Journal.Pone.0004346 |
0.366 |
|
2008 |
Agarwal P, Searls DB. Literature mining in support of drug discovery. Briefings in Bioinformatics. 9: 479-92. PMID 18820304 DOI: 10.1093/Bib/Bbn035 |
0.325 |
|
2008 |
Tanner SW, Agarwal P. Gene Vector Analysis (Geneva): a unified method to detect differentially-regulated gene sets and similar microarray experiments. Bmc Bioinformatics. 9: 348. PMID 18721468 DOI: 10.1186/1471-2105-9-348 |
0.309 |
|
2005 |
Liu R, Agarwal P. Computational identification of transcription factors involved in early cellular response to a stimulus. Journal of Bioinformatics and Computational Biology. 3: 949-64. PMID 16078369 DOI: 10.1142/S0219720005001405 |
0.673 |
|
2005 |
Rajagopalan D, Agarwal P. Inferring pathways from gene lists using a literature-derived network of biological relationships Bioinformatics. 21: 788-793. PMID 15509611 DOI: 10.1093/Bioinformatics/Bti069 |
0.348 |
|
2004 |
Kemmer D, Faxén M, Hodges E, Lim J, Herzog E, Ljungström E, Lundmark A, Olsen MK, Podowski R, Sonnhammer EL, Nilsson P, Reimers M, Lenhard B, Roberds SL, Wahlestedt C, ... ... Agarwal P, et al. Exploring the foundation of genomics: a northern blot reference set for the comparative analysis of transcript profiling technologies. Comparative and Functional Genomics. 5: 584-95. PMID 18629180 DOI: 10.1002/Cfg.443 |
0.319 |
|
2003 |
Guigo R, Dermitzakis ET, Agarwal P, Ponting CP, Parra G, Reymond A, Abril JF, Keibler E, Lyle R, Ucla C, Antonarakis SE, Brent MR. Comparison of mouse and human genomes followed by experimental verification yields an estimated 1,019 additional genes. Proceedings of the National Academy of Sciences of the United States of America. 100: 1140-5. PMID 12552088 DOI: 10.1073/Pnas.0337561100 |
0.334 |
|
2003 |
Parra G, Agarwal P, Abril JF, Wiehe T, Fickett JW, Guigó R. Comparative gene prediction in human and mouse. Genome Research. 13: 108-17. PMID 12529313 DOI: 10.1101/Gr.871403 |
0.307 |
|
2001 |
Betts MJ, Guigó R, Agarwal P, Russell RB. Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution? The Embo Journal. 20: 5354-60. PMID 11574467 DOI: 10.1093/Emboj/20.19.5354 |
0.32 |
|
2000 |
Guigó R, Agarwal P, Abril JF, Burset M, Fickett JW. An assessment of gene prediction accuracy in large DNA sequences. Genome Research. 10: 1631-42. PMID 11042160 DOI: 10.1101/Gr.122800 |
0.338 |
|
1998 |
Agarwal P, States DJ. Comparative accuracy of methods for protein sequence similarity search. Bioinformatics (Oxford, England). 14: 40-7. PMID 9520500 DOI: 10.1093/Bioinformatics/14.1.40 |
0.566 |
|
1996 |
Agarwal P, States DJ. A Bayesian evolutionary distance for parametrically aligned sequences. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 3: 1-17. PMID 8697232 DOI: 10.1089/Cmb.1996.3.1 |
0.544 |
|
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