Kenneth S Polonsky - Publications

Affiliations: 
Medicine Washington University, Saint Louis, St. Louis, MO 

236 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Sun J, Polonsky K, Ren D. IER3IP1 Regulates Beta-Cell Survival Diabetes. 67. DOI: 10.2337/Db18-2103-P  0.372
2016 Sun J, Mao LQ, Polonsky KS, Ren DC. Pancreatic β-Cell Death Due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax But Not Bak. The Journal of Biological Chemistry. PMID 27137932 DOI: 10.1074/Jbc.M115.705293  0.389
2015 Polonsky KS, Rubenstein AH. Donald F. Steiner, MD, 1930-2014: pioneering diabetes researcher. Diabetologia. 58: 419-21. PMID 25617020 DOI: 10.1007/S00125-015-3495-X  0.466
2015 Philipson LH, Bell G, Polonsky KS. Donald F. Steiner MD, 1930-2014: discoverer of proinsulin. Proceedings of the National Academy of Sciences of the United States of America. 112: 940-1. PMID 25561547 DOI: 10.1073/Pnas.1423774112  0.368
2015 Polonsky KS, Rubenstein AH. Donald F. Steiner, MD, 1930–2014: Pioneering diabetes researcher Diabetologia. 58: 419-421. DOI: 10.1007/s00125-015-3495-x  0.396
2014 Ren D, Sun J, Mao L, Ye H, Polonsky KS. BH3-only molecule Bim mediates β-cell death in IRS2 deficiency. Diabetes. 63: 3378-87. PMID 24760140 DOI: 10.2337/Db13-1814  0.428
2014 Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. The Journal of Clinical Endocrinology and Metabolism. 99: 1983-92. PMID 24712577 DOI: 10.1210/Jc.2014-1425  0.309
2014 Ren D, Sun J, Wang C, Ye H, Mao L, Cheng EH, Bell GI, Polonsky KS. Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiency. Diabetes. 63: 2744-50. PMID 24658302 DOI: 10.2337/Db13-1513  0.363
2014 Chowdhury S, Reeds DN, Crimmins DL, Patterson BW, Laciny E, Wang S, Tran HD, Griest TA, Rometo DA, Dunai J, Wallendorf MJ, Ladenson JH, Polonsky KS, Wice BM. Xenin-25 delays gastric emptying and reduces postprandial glucose levels in humans with and without type 2 diabetes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G301-9. PMID 24356886 DOI: 10.1152/Ajpgi.00383.2013  0.557
2013 Pedersen MG, Mosekilde E, Polonsky KS, Luciani DS. Complex patterns of metabolic and Ca²⁺ entrainment in pancreatic islets by oscillatory glucose. Biophysical Journal. 105: 29-39. PMID 23823221 DOI: 10.1016/J.Bpj.2013.05.036  0.755
2012 Han DH, Kim SH, Higashida K, Jung SR, Polonsky KS, Klein S, Holloszy JO. Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats. Metabolism: Clinical and Experimental. 61: 1615-21. PMID 22571876 DOI: 10.1016/J.Metabol.2012.04.008  0.484
2012 Wice BM, Reeds DN, Tran HD, Crimmins DL, Patterson BW, Dunai J, Wallendorf MJ, Ladenson JH, Villareal DT, Polonsky KS. Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes. Diabetes. 61: 1793-800. PMID 22522617 DOI: 10.2337/Db11-1451  0.593
2012 Klein S, Fabbrini E, Patterson BW, Polonsky KS, Schiavon CA, Correa JL, Salles JE, Wajchenberg BL, Cohen R. Moderate effect of duodenal-jejunal bypass surgery on glucose homeostasis in patients with type 2 diabetes. Obesity (Silver Spring, Md.). 20: 1266-72. PMID 22262157 DOI: 10.1038/Oby.2011.377  0.434
2011 Reeds DN, Patterson BW, Okunade A, Holloszy JO, Polonsky KS, Klein S. Ginseng and ginsenoside Re do not improve β-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes. Diabetes Care. 34: 1071-6. PMID 21411505 DOI: 10.2337/Dc10-2299  0.416
2010 Fujimoto K, Ford EL, Tran H, Wice BM, Crosby SD, Dorn GW, Polonsky KS. Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes Journal of Clinical Investigation. 120: 4031-4039. PMID 20978346 DOI: 10.1172/Jci44011  0.404
2010 Fujimoto K, Chen Y, Polonsky KS, Dorn GW. Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency. Proceedings of the National Academy of Sciences of the United States of America. 107: 10214-9. PMID 20479245 DOI: 10.1073/Pnas.0914209107  0.41
2010 Wice BM, Wang S, Crimmins DL, Diggs-Andrews KA, Althage MC, Ford EL, Tran H, Ohlendorf M, Griest TA, Wang Q, Fisher SJ, Ladenson JH, Polonsky KS. Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism. The Journal of Biological Chemistry. 285: 19842-53. PMID 20421298 DOI: 10.1074/Jbc.M110.129304  0.574
2010 Cheverud JM, Fawcett GL, Jarvis JP, Norgard EA, Pavlicev M, Pletscher LS, Polonsky KS, Ye H, Bell GI, Semenkovich CF. Calpain-10 is a component of the obesity-related quantitative trait locus Adip1. Journal of Lipid Research. 51: 907-13. PMID 20388922 DOI: 10.1194/Jlr.M900128  0.346
2010 Villareal DT, Polonsky KS. Response letter to comment on: Villareal et al. (2009) TCF7L2 Variant rs7903146 Affects the Risk of Type 2 Diabetes by Modulating Incretin Action. Diabetes; 59:479–485 Diabetes. 59. DOI: 10.2337/Db10-0303  0.505
2009 Johnson JD, Otani K, Bell GI, Polonsky KS. Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic β-cells. Islets. 1: 242-8. PMID 21099278 DOI: 10.4161/Isl.1.3.9780  0.701
2009 Fujimoto K, Polonsky KS. Pdx1 and other factors that regulate pancreatic β-cell survival Diabetes, Obesity and Metabolism. 11: 30-37. PMID 19817786 DOI: 10.1111/J.1463-1326.2009.01121.X  0.378
2009 Kawai T, Ng MC, Hayes MG, Yoshiuchi I, Tsuchiya T, Robertson H, Cox NJ, Polonsky KS, Bell GI, Ehrmann DA. Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome. Diabetes Research and Clinical Practice. 86: 186-92. PMID 19782423 DOI: 10.1016/J.Diabres.2009.09.002  0.36
2009 Fujimoto K, Hanson PT, Tran H, Ford EL, Han Z, Johnson JD, Schmidt RE, Green KG, Wice BM, Polonsky KS. Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation. The Journal of Biological Chemistry. 284: 27664-73. PMID 19654319 DOI: 10.1074/Jbc.M109.041616  0.553
2009 Villareal DT, Koster JC, Robertson H, Akrouh A, Miyake K, Bell GI, Patterson BW, Nichols CG, Polonsky KS. Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance. Diabetes. 58: 1869-78. PMID 19491206 DOI: 10.2337/Db09-0025  0.572
2009 Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, Ford EL, Herrera PL, Polonsky KS, McGuinness OP, Kulkarni RN. Insulin signaling in alpha cells modulates glucagon secretion in vivo. Cell Metabolism. 9: 350-61. PMID 19356716 DOI: 10.1016/J.Cmet.2009.02.007  0.553
2009 Uchizono Y, Baldwin AC, Sakuma H, Pugh W, Polonsky KS, Hara M. Role of HNF-1alpha in regulating the expression of genes involved in cellular growth and proliferation in pancreatic beta-cells. Diabetes Research and Clinical Practice. 84: 19-26. PMID 19181415 DOI: 10.1016/J.Diabres.2008.12.014  0.475
2009 Polonsky KS. Evolution of beta-cell dysfunction in impaired glucose tolerance and diabetes. Experimental and Clinical Endocrinology & Diabetes. 107. PMID 10522836 DOI: 10.1055/S-0029-1212166  0.616
2008 Jeffrey KD, Alejandro EU, Luciani DS, Kalynyak TB, Hu X, Li H, Lin Y, Townsend RR, Polonsky KS, Johnson JD. Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 8452-7. PMID 18550819 DOI: 10.1073/Pnas.0711232105  0.775
2008 Little RR, Rohlfing CL, Tennill AL, Madsen RW, Polonsky KS, Myers GL, Greenbaum CJ, Palmer JP, Rogatsky E, Stein DT. Standardization of C-peptide measurements. Clinical Chemistry. 54: 1023-6. PMID 18420730 DOI: 10.1373/Clinchem.2007.101287  0.328
2008 Althage MC, Ford EL, Wang S, Tso P, Polonsky KS, Wice BM. Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet Journal of Biological Chemistry. 283: 18365-18376. PMID 18420580 DOI: 10.1074/Jbc.M710466200  0.484
2008 Villareal DT, Banks MR, Patterson BW, Polonsky KS, Klein S. Weight loss therapy improves pancreatic endocrine function in obese older adults. Obesity (Silver Spring, Md.). 16: 1349-54. PMID 18388888 DOI: 10.1038/Oby.2008.226  0.489
2008 Hara M, Shen J, Pugh W, Polonsky KS, Le Beau MM, Bell GI. Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 115: 654-61. PMID 18058600 DOI: 10.1055/S-2007-982514  0.39
2007 Wiedmeyer HM, Polonsky KS, Myers GL, Little RR, Greenbaum CJ, Goldstein DE, Palmer JP. International comparison of C-peptide measurements Clinical Chemistry. 53: 784-787. PMID 17332147 DOI: 10.1373/Clinchem.2006.081570  0.334
2006 Johnson JD, Bernal-Mizrachi E, Alejandro EU, Han Z, Kalynyak TB, Li H, Beith JL, Gross J, Warnock GL, Townsend RR, Permutt MA, Polonsky KS. Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome. Proceedings of the National Academy of Sciences of the United States of America. 103: 19575-80. PMID 17158802 DOI: 10.1073/Pnas.0604208103  0.809
2006 Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, Secchi A, Brendel MD, Berney T, Brennan DC, Cagliero E, Alejandro R, Ryan EA, DiMercurio B, Morel P, ... Polonsky KS, et al. International trial of the Edmonton protocol for islet transplantation. The New England Journal of Medicine. 355: 1318-30. PMID 17005949 DOI: 10.1056/Nejmoa061267  0.467
2006 Johnson JD, Ford EL, Bernal-Mizrachi E, Kusser KL, Luciani DS, Han Z, Tran H, Randall TD, Lund FE, Polonsky KS. Suppressed insulin signaling and increased apoptosis in CD38-null islets. Diabetes. 55: 2737-46. PMID 17003338 DOI: 10.2337/Db05-1455  0.784
2006 Polonsky KS. Retinol-binding protein 4, insulin resistance, and type 2 diabetes. The New England Journal of Medicine. 354: 2596-8. PMID 16775241 DOI: 10.1056/Nejme068091  0.46
2006 Otani K, Polonsky KS, Holloszy JO, Han DH. Inhibition of calpain results in impaired contraction-stimulated GLUT4 translocation in skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 291: E544-8. PMID 16705056 DOI: 10.1152/Ajpendo.00510.2005  0.442
2006 Luciani DS, Misler S, Polonsky KS. Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets. The Journal of Physiology. 572: 379-92. PMID 16455690 DOI: 10.1113/Jphysiol.2005.101766  0.782
2006 Dalla Man C, Campioni M, Polonsky KS, Basu R, Rizza RA, Toffolo G, Cobelli C. Two-hour seven-sample oral glucose tolerance test and meal protocol: minimal model assessment of beta-cell responsivity and insulin sensitivity in nondiabetic individuals. Diabetes. 54: 3265-73. PMID 16249454 DOI: 10.2337/Diabetes.54.11.3265  0.479
2005 Levisetti MG, Polonsky KS. Diabetic pancreatic beta cells ARNT all they should be. Cell Metabolism. 2: 78-80. PMID 16098823 DOI: 10.1016/J.Cmet.2005.07.005  0.427
2005 Kim SH, Abbasi F, Chu JW, McLaughlin TL, Lamendola C, Polonsky KS, Reaven GM. Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals. Diabetes. 54: 2447-52. PMID 16046313 DOI: 10.2337/Diabetes.54.8.2447  0.59
2005 Dalla Man C, Yarasheski KE, Caumo A, Robertson H, Toffolo G, Polonsky KS, Cobelli C. Insulin sensitivity by oral glucose minimal models: validation against clamp. American Journal of Physiology. Endocrinology and Metabolism. 289: E954-9. PMID 16014353 DOI: 10.1152/Ajpendo.00076.2005  0.475
2005 Ohsugi M, Cras-Méneur C, Zhou Y, Bernal-Mizrachi E, Johnson JD, Luciani DS, Polonsky KS, Permutt MA. Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion. The Journal of Biological Chemistry. 280: 4992-5003. PMID 15546857 DOI: 10.1074/Jbc.M411727200  0.815
2004 Bernal-Mizrachi E, Fatrai S, Johnson JD, Ohsugi M, Otani K, Han Z, Polonsky KS, Permutt MA. Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells. The Journal of Clinical Investigation. 114: 928-36. PMID 15467831 DOI: 10.1172/Jci20016  0.667
2004 Johnson JD, Han Z, Otani K, Ye H, Zhang Y, Wu H, Horikawa Y, Misler S, Bell GI, Polonsky KS. RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. The Journal of Biological Chemistry. 279: 24794-802. PMID 15044459 DOI: 10.1074/Jbc.M401216200  0.729
2004 Johnson JD, Kuang S, Misler S, Polonsky KS. Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 878-80. PMID 15033925 DOI: 10.1096/Fj.03-1280Fje  0.796
2004 Otani K, Han DH, Ford EL, Garcia-Roves PM, Ye H, Horikawa Y, Bell GI, Holloszy JO, Polonsky KS. Calpain system regulates muscle mass and glucose transporter GLUT4 turnover. The Journal of Biological Chemistry. 279: 20915-20. PMID 15014085 DOI: 10.1074/Jbc.M400213200  0.373
2004 Palmer JP, Fleming GA, Greenbaum CJ, Herold KC, Jansa LD, Kolb H, Lachin JM, Polonsky KS, Pozzilli P, Skyler JS, Steffes MW. C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001. Diabetes. 53: 250-64. PMID 14693724 DOI: 10.2337/Diabetes.53.1.250  0.463
2004 Ehrmann DA, Breda E, Corcoran MC, Cavaghan MK, Imperial J, Toffolo G, Cobelli C, Polonsky KS. Impaired beta-cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome. American Journal of Physiology. Endocrinology and Metabolism. 287: E241-6. PMID 14665448 DOI: 10.1152/Ajpendo.00475.2003  0.538
2004 Otani K, Kulkarni RN, Baldwin AC, Krutzfeldt J, Ueki K, Stoffel M, Kahn CR, Polonsky KS. Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice. American Journal of Physiology. Endocrinology and Metabolism. 286: E41-9. PMID 14519599 DOI: 10.1152/Ajpendo.00533.2001  0.601
2004 Palmer JP, Fleming GA, Greenbaum CJ, Herold KC, Jansa LD, Kolb H, Lachin JM, Polonsky KS, Pozzilli P, Skyler JS, Steffes MW. Erratum: C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve β-cell function: Report of an ADA workshop, 21-22 October 2001 (Diabetes (2004) 53 (250-264)) Diabetes. 53. DOI: 10.2337/Diabetes.53.7.1934  0.325
2003 Zhou YP, Sreenan S, Pan CY, Currie KP, Bindokas VP, Horikawa Y, Lee JP, Ostrega D, Ahmed N, Baldwin AC, Cox NJ, Fox AP, Miller RJ, Bell GI, Polonsky KS. A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin. Metabolism: Clinical and Experimental. 52: 528-34. PMID 12759879 DOI: 10.1053/Meta.2003.50091  0.582
2003 Polonsky KS, Bell GI. Organ alchemy: producing insulin in the liver. Nature Medicine. 9: 504-5. PMID 12724755 DOI: 10.1038/Nm0503-504  0.531
2003 Johnson JD, Ahmed NT, Luciani DS, Han Z, Tran H, Fujita J, Misler S, Edlund H, Polonsky KS. Increased islet apoptosis in Pdx1+/- mice. The Journal of Clinical Investigation. 111: 1147-60. PMID 12697734 DOI: 10.1172/Jci16537  0.834
2003 Bindokas VP, Kuznetsov A, Sreenan S, Polonsky KS, Roe MW, Philipson LH. Visualizing superoxide production in normal and diabetic rat islets of Langerhans. The Journal of Biological Chemistry. 278: 9796-801. PMID 12514170 DOI: 10.1074/Jbc.M206913200  0.437
2003 Breda E, Toffolo G, Polonsky KS, Cobelli C. Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times. Diabetes. S227-33. PMID 11815484 DOI: 10.2337/Diabetes.51.2007.S227  0.591
2002 Xie JT, Zhou Y-, Dey L, Attele AS, Wu JA, Gu M, Polonsky KS, Yuan C-. Ginseng berry reduces blood glucose and body weight in db/db mice. Phytomedicine. 9: 254-258. PMID 12046868 DOI: 10.1078/0944-7113-00106  0.334
2002 Ehrmann DA, Breda E, Cavaghan MK, Bajramovic S, Imperial J, Toffolo G, Cobelli C, Polonsky KS. Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance. Diabetologia. 45: 509-17. PMID 12032626 DOI: 10.1007/S00125-002-0776-Y  0.533
2002 Attele AS, Zhou YP, Xie JT, Wu JA, Zhang L, Dey L, Pugh W, Rue PA, Polonsky KS, Yuan CS. Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes. 51: 1851-8. PMID 12031973 DOI: 10.2337/Diabetes.51.6.1851  0.418
2002 Hofmann EA, Polonsky KS, Weiss RE. Diagnosis of acromegaly in a patient with type 1 diabetes mellitus. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 8: 113-8. PMID 11942776 DOI: 10.4158/Ep.8.2.113  0.307
2001 Bell GI, Polonsky KS. Diabetes mellitus and genetically programmed defects in β-cell function Nature. 414: 788-791. PMID 11742410 DOI: 10.1038/414788A  0.404
2001 Shih DQ, Screenan S, Munoz KN, Philipson L, Pontoglio M, Yaniv M, Polonsky KS, Stoffel M. Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes. 50: 2472-80. PMID 11679424 DOI: 10.2337/Diabetes.50.11.2472  0.397
2001 Tuttle RL, Gill NS, Pugh W, Lee JP, Koeberlein B, Furth EE, Polonsky KS, Naji A, Birnbaum MJ. Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha. Nature Medicine. 7: 1133-7. PMID 11590437 DOI: 10.1038/Nm1001-1133  0.469
2001 Fajans SS, Bell GI, Polonsky KS. Molecular Mechanisms and Clinical Pathophysiology of Maturity-Onset Diabetes of the Young The New England Journal of Medicine. 345: 971-980. PMID 11575290 DOI: 10.1056/Nejmra002168  0.311
2001 Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, ... Polonsky KS, et al. Calpains play a role in insulin secretion and action. Diabetes. 50: 2013-20. PMID 11522666 DOI: 10.2337/Diabetes.50.9.2013  0.573
2001 Gautier J, Wilson C, Weyer C, Mott D, Knowler WC, Cavaghan M, Polonsky KS, Bogardus C, Pratley RE. Low Acute Insulin Secretory Responses in Adult Offspring of People With Early Onset Type 2 Diabetes Diabetes. 50: 1828-1833. PMID 11473045 DOI: 10.2337/Diabetes.50.8.1828  0.512
2001 Brandt A, Katschinski M, Arnold R, Polonsky KS, Göke B, Byrne MM. GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve. American Journal of Physiology-Endocrinology and Metabolism. 281. PMID 11440899 DOI: 10.1152/Ajpendo.2001.281.2.E242  0.547
2001 Polonsky KS, Semenkovich CF. The pancreatic β cell heats up: UCP2 and insulin secretion in diabetes Cell. 105: 705-707. PMID 11440712 DOI: 10.1016/S0092-8674(01)00389-0  0.475
2001 Grimberg A, Ferry RJ, Kelly A, Koo-McCoy S, Polonsky K, Glaser B, Permutt MA, Aguilar-Bryan L, Stafford D, Thornton PS, Baker L, Stanley CA. Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations. Diabetes. 50: 322-328. PMID 11272143 DOI: 10.2337/Diabetes.50.2.322  0.531
2001 Breda E, Cavaghan MK, Toffolo G, Polonsky KS, Cobelli C. Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity. Diabetes. 50: 150-8. PMID 11147781 DOI: 10.2337/Diabetes.50.1.150  0.561
2001 Toffolo G, Breda E, Cavaghan MK, Ehrmann DA, Polonsky KS, Cobelli C. Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models. American Journal of Physiology. Endocrinology and Metabolism. 280: E2-10. PMID 11120653 DOI: 10.1152/Ajpendo.2001.280.1.E2  0.589
2001 Fajans SS, Bell GI, Herman WH, Polonsky KS, Halter JB. Beta-cell dysfunction in prediabetic and diabetic MODY subjects Journal of Diabetes and Its Complications. 15: 15. DOI: 10.1016/S1056-8727(00)00102-1  0.341
2000 Sreenan SK, Mittal AA, Dralyuk F, Pugh WL, Polonsky KS, Roe MW. Glucagon-like peptide-1 stimulates insulin secretion by a Ca2+-independent mechanism in Zucker diabetic fatty rat islets of Langerhans. Metabolism-Clinical and Experimental. 49: 1579-1587. PMID 11145120 DOI: 10.1053/Meta.2000.18555  0.578
2000 Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PEH, Del Bosque-Plata L, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus Nature Genetics. 26: 163-175. PMID 11017071 DOI: 10.1038/79876  0.332
2000 Polonsky K. Dynamics of insulin secretion in obesity and diabetes. International Journal of Obesity. 24. PMID 10997604 DOI: 10.1038/Sj.Ijo.0801273  0.548
2000 Cavaghan MK, Ehrmann DA, Polonsky KS. Interactions between insulin resistance and insulin secretion in the development of glucose intolerance Journal of Clinical Investigation. 106: 329-333. PMID 10930434 DOI: 10.1172/Jci10761  0.569
2000 Hollingdal M, Juhl CB, Pincus SM, Sturis J, Veldhuis JD, Polonsky KS, Pørksen N, Schmitz O. Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes. Diabetes. 49: 1334-40. PMID 10923634 DOI: 10.2337/Diabetes.49.8.1334  0.604
2000 Jones CN, Abbasi F, Carantoni M, Polonsky KS, Reaven GM. Roles of insulin resistance and obesity in regulation of plasma insulin concentrations. American Journal of Physiology. Endocrinology and Metabolism. 278: E501-8. PMID 10710505 DOI: 10.1152/Ajpendo.2000.278.3.E501  0.584
2000 Zhou YP, Pena JC, Roe MW, Mittal A, Levisetti M, Baldwin AC, Pugh W, Ostrega D, Ahmed N, Bindokas VP, Philipson LH, Hanahan D, Thompson CB, Polonsky KS. Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 278: E340-51. PMID 10662719 DOI: 10.1152/Ajpendo.2000.278.2.E340  0.505
1999 Plat L, Leproult R, L'Hermite-Baleriaux M, Fery F, Mockel J, Polonsky KS, Van Cauter E. Metabolic effects of short-term elevations of plasma cortisol are more pronounced in the evening than in the morning. The Journal of Clinical Endocrinology and Metabolism. 84: 3082-92. PMID 10487669 DOI: 10.1210/Jcem.84.9.5978  0.584
1999 Zhou YP, Cockburn BN, Pugh W, Polonsky KS. Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: role of enhanced fuel metabolism. Metabolism: Clinical and Experimental. 48: 857-64. PMID 10421226 DOI: 10.1016/S0026-0495(99)90219-6  0.585
1999 Sreenan S, Pick AJ, Levisetti M, Baldwin AC, Pugh W, Polonsky KS. Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse. Diabetes. 48: 989-96. PMID 10331402 DOI: 10.2337/Diabetes.48.5.989  0.435
1999 Wiesenthal SR, Sandhu H, McCall RH, Tchipashvili V, Yoshii H, Polonsky K, Shi ZQ, Lewis GF, Mari A, Giacca A. Free fatty acids impair hepatic insulin extraction in vivo. Diabetes. 48: 766-774. PMID 10102693 DOI: 10.2337/Diabetes.48.4.766  0.523
1998 McCall RH, Wiesenthal SR, Shi ZQ, Polonsky K, Giacca A. Insulin acutely suppresses glucose production by both peripheral and hepatic effects in normal dogs. American Journal of Physiology. Endocrinology and Metabolism. 274: E346-E356. PMID 29590782 DOI: 10.1152/Ajpendo.1998.274.2.E346  0.484
1998 Sreenan SK, Cockburn BN, Baldwin AC, Ostrega DM, Levisetti M, Grupe A, Bell GI, Stewart TA, Roe MW, Polonsky KS. Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice. Diabetes. 47: 1881-8. PMID 9836519 DOI: 10.2337/Diabetes.47.12.1881  0.572
1998 Dukes ID, Sreenan S, Roe MW, Levisetti M, Zhou Y, Ostrega D, Bell GI, Pontoglio M, Yaniv M, Philipson L, Polonsky KS. Defective Pancreatic β-Cell Glycolytic Signaling in Hepatocyte Nuclear Factor-1α-deficient Mice Journal of Biological Chemistry. 273: 24457-24464. PMID 9733737 DOI: 10.1074/Jbc.273.38.24457  0.479
1998 Byrne MM, Gliem K, Wank U, Arnold R, Katschinski M, Polonsky KS, Goke B. Glucagon-Like Peptide 1 Improves the Ability of the β-Cell to Sense and Respond to Glucose in Subjects With Impaired Glucose Tolerance Diabetes. 47: 1259-1265. PMID 9703326 DOI: 10.2337/Diab.47.8.1259  0.526
1998 Pontoglio M, Sreenan S, Roe M, Pugh W, Ostrega D, Doyen A, Pick AJ, Baldwin A, Velho G, Froguel P, Levisetti M, Bonner-Weir S, Bell GI, Yaniv M, Polonsky KS. Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. The Journal of Clinical Investigation. 101: 2215-22. PMID 9593777 DOI: 10.1172/Jci2548  0.465
1998 Polonsky KS, Sturis J, Van Cauter E. Temporal profiles and clinical significance of pulsatile insulin secretion. Hormone Research. 49: 178-84. PMID 9550122 DOI: 10.1159/000023168  0.607
1998 Zhou Y-, Teng D, Dralyuk F, Ostrega D, Roe MW, Philipson L, Polonsky KS. Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. Journal of Clinical Investigation. 101: 1623-1632. PMID 9541492 DOI: 10.1172/Jci1245  0.327
1998 Pick A, Clark J, Kubstrup C, Levisetti M, Pugh W, Bonner-Weir S, Polonsky KS. Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes. 47: 358-64. PMID 9519740 DOI: 10.2337/Diabetes.47.3.358  0.42
1998 Maggs DG, Buchanan TA, Burant CF, Cline G, Gumbiner B, Hsueh WA, Inzucchi S, Kelley D, Nolan J, Olefsky JM, Polonsky KS, Silver D, Valiquett TR, Shulman GI. Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Annals of Internal Medicine. 128: 176-85. PMID 9454525 DOI: 10.7326/0003-4819-128-3-199802010-00002  0.446
1998 Ehrmann DA, Schneider DJ, Sobel BE, Cavaghan MK, Imperial J, Rosenfield RL, Polonsky KS. Troglitazone Improves Defects in Insulin Action, Insulin Secretion, Ovarian Steroidogenesis, and Fibrinolysis in Women With Polycystic Ovary Syndrome Obstetrical & Gynecological Survey. 53: 28-30. DOI: 10.1097/00006254-199801000-00017  0.495
1997 Maheux P, Chen YDI, Polonsky KS, Reaven GM. Evidence that insulin can directly inhibit hepatic glucose production. Diabetologia. 40: 1300-1306. PMID 9389422 DOI: 10.1007/S001250050824  0.527
1997 Herman WH, Fajans SS, Smith MJ, Polonsky KS, Bell GI, Halter JB. Diminished Insulin and Glucagon Secretory Responses to Arginine in Nondiabetic Subjects With a Mutation in the Hepatocyte Nuclear Factor–4α/MODY1 Gene Diabetes. 46: 1749-1754. PMID 9356021 DOI: 10.2337/Diab.46.11.1749  0.558
1997 Regazzi R, Verchere CB, Halban PA, Polonsky KS. Insulin production: from gene to granule Diabetologia. 40. PMID 9345643 DOI: 10.1007/Bf03168184  0.569
1997 Van Cauter E, Polonsky KS, Scheen AJ. Roles of circadian rhythmicity and sleep in human glucose regulation. Endocrine Reviews. 18: 716-38. PMID 9331550 DOI: 10.1210/Edrv.18.5.0317  0.511
1997 Cockburn BN, Ostrega DM, Sturis J, Kubstrup C, Polonsky KS, Bell GI. Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes. Diabetes. 46: 1434-9. PMID 9287043 DOI: 10.2337/Diab.46.9.1434  0.476
1997 Polonsky KS, Byrne MM, Sturis J. Alternative insulin delivery systems: how demanding should the patient be? Diabetologia. 40. PMID 9248709 DOI: 10.1007/S001250051417  0.458
1997 Cavaghan MK, Ehrmann DA, Byrne MM, Polonsky KS. Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance. Journal of Clinical Investigation. 100: 530-537. PMID 9239399 DOI: 10.1172/Jci119562  0.581
1997 Ehrmann DA, Schneider DJ, Sobel BE, Cavaghan MK, Imperial J, Rosenfield RL, Polonsky KS. Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism. 82: 2108-16. PMID 9215280 DOI: 10.1210/Jcem.82.7.4069  0.563
1997 Jones CN, Pei D, Staris P, Polonsky KS, Chen YD, Reaven GM. Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals. The Journal of Clinical Endocrinology and Metabolism. 82: 1834-8. PMID 9177392 DOI: 10.1210/Jcem.82.6.3979  0.601
1997 Warren-Perry MG, Manley SE, Ostrega D, Polonsky K, Mussett S, Brown P, Turner RC. A novel point mutation in the insulin gene giving rise to hyperproinsulinemia. The Journal of Clinical Endocrinology and Metabolism. 82: 1629-31. PMID 9141561 DOI: 10.1210/Jcem.82.5.3914  0.505
1997 Del Sindaco P, Casucci G, Pampanelli S, Polonsky K, Fanelli C, Torlone E, Santeusanio F, Brunetti P, Bolli GB. Late post-prandial hypoglycaemia as the sole presenting feature of secreting pancreatic beta-cell adenoma in a subtotally gastrectomized patient. European Journal of Endocrinology. 136: 96-9. PMID 9037134 DOI: 10.1530/EJE.0.1360096  0.376
1997 Ehrmann DA, Cavaghan MK, Imperial J, Sturis J, Rosenfield RL, Polonsky KS. Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome The Journal of Clinical Endocrinology and Metabolism. 82: 524-530. PMID 9024248 DOI: 10.1210/Jcem.82.2.3722  0.531
1996 Gumbiner B, Van Cauter E, Beltz WF, Ditzler TM, Griver K, Polonsky KS, Henry RR. Abnormalities of insulin pulsatility and glucose oscillations during meals in obese noninsulin-dependent diabetic patients: effects of weight reduction. The Journal of Clinical Endocrinology and Metabolism. 81: 2061-8. PMID 8964829 DOI: 10.1210/Jcem.81.6.8964829  0.589
1996 Yamagata K, Oda N, Kaisaki PJ, Menzel S, Furuta H, Vaxillaire M, Southam L, Cox RD, Lathrop GM, Boriraj VV, Chen X, Cox NJ, Oda Y, Yano H, Le Beau MM, ... ... Polonsky KS, et al. Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3) Nature. 384: 455-458. PMID 8945470 DOI: 10.1038/384455A0  0.386
1996 Byrne MM, Sturis J, Sobel RJ, Polonsky KS. Elevated plasma glucose 2 h postchallenge predicts defects in beta-cell function. American Journal of Physiology-Endocrinology and Metabolism. 270. PMID 8928761 DOI: 10.1152/Ajpendo.1996.270.4.E572  0.482
1996 Biston P, Van Cauter E, Ofek G, Linkowski P, Polonsky KS, Degaute JP. Diurnal variations in cardiovascular function and glucose regulation in normotensive humans. Hypertension. 28: 863-71. PMID 8901836 DOI: 10.1161/01.Hyp.28.5.863  0.518
1996 Sreenan S, Sturis J, Pugh W, Burant CF, Polonsky KS. Prevention of hyperglycemia in the Zucker diabetic fatty rat by treatment with metformin or troglitazone American Journal of Physiology-Endocrinology and Metabolism. 271. PMID 8897863 DOI: 10.1152/Ajpendo.1996.271.4.E742  0.305
1996 Fajans SS, Bell GI, Bowden DW, Halter JB, Polonsky KS. Maturity onset diabetes of the young (MODY) Diabetic Medicine. 13. PMID 8894490  0.351
1996 MacDonald MJ, Tang J, Polonsky KS. Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats. Diabetes. 45: 1626-30. PMID 8866570 DOI: 10.2337/Diab.45.11.1626  0.374
1996 Byrne MM, Sturis J, Menzel S, Yamagata K, Fajans SS, Dronsfield MJ, Bain SC, Hattersley AT, Velho G, Froguel P, Bell GI, Polonsky KS. Altered Insulin Secretory Responses to Glucose in Diabetic and Nondiabetic Subjects With Mutations in the Diabetes Susceptibility Gene MODY3 on Chromosome 12 Diabetes. 45: 1503-1510. PMID 8866553 DOI: 10.2337/Diab.45.11.1503  0.546
1996 Bell GI, Pilkis SJ, Weber IT, Polonsky KS. Glucokinase mutations, insulin secretion, and diabetes mellitus. Annual Review of Physiology. 58: 171-86. PMID 8815790 DOI: 10.1146/Annurev.Ph.58.030196.001131  0.582
1996 Roe MW, Worley JF, Tokuyama Y, Philipson LH, Sturis J, Tang J, Dukes ID, Bell GI, Polonsky KS. NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity. The American Journal of Physiology. 270: E133-40. PMID 8772485 DOI: 10.1152/Ajpendo.1996.270.1.E133  0.536
1996 Plat L, Byrne MM, Sturis J, Polonsky KS, Mockel J, Féry F, Van Cauter E. Effects of morning cortisol elevation on insulin secretion and glucose regulation in humans. The American Journal of Physiology. 270: E36-42. PMID 8772471 DOI: 10.1152/Ajpendo.1996.270.1.E36  0.565
1996 Montgomery TM, Nelson RW, Feldman EC, Robertson K, Polonsky KS. Basal and glucagon-stimulated plasma C-peptide concentrations in healthy dogs, dogs with diabetes mellitus, and dogs with hyperadrenocorticism. Journal of Veterinary Internal Medicine. 10: 116-122. PMID 8743209 DOI: 10.1111/J.1939-1676.1996.Tb02042.X  0.543
1996 Scheen AJ, Sturis J, Polonsky KS, Van Cauter E. Alterations in the ultradian oscillations of insulin secretion and plasma glucose in aging. Diabetologia. 39: 564-72. PMID 8739916 DOI: 10.1007/Bf00403303  0.564
1996 Tang J, Pugh W, Polonsky KS, Zhang H. Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats. American Journal of Physiology-Endocrinology and Metabolism. 270. PMID 8638699 DOI: 10.1152/Ajpendo.1996.270.3.E504  0.529
1996 Tokuyama Y, Fan Z, Furuta H, Makielski JC, Polonsky KS, Bell GI, Yano H. Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. Biochemical and Biophysical Research Communications. 220: 532-8. PMID 8607800 DOI: 10.1006/Bbrc.1996.0439  0.342
1996 Velho G, Byrne MM, Clément K, Sturis J, Pueyo ME, Blanché H, Vionnet N, Fiet J, Passa P, Robert J, Polonsky KS, Froguel P. Clinical Phenotypes, Insulin Secretion, and Insulin Sensitivity in Kindreds With Maternally Inherited Diabetes and Deafness Due to Mitochondrial tRNALeu(UUR) Gene Mutation Diabetes. 45: 478-487. PMID 8603770 DOI: 10.2337/Diab.45.4.478  0.601
1996 Polonsky KS, Sturis J, Bell GI. Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance. The New England Journal of Medicine. 334: 777-783. PMID 8592553 DOI: 10.1056/Nejm199603213341207  0.547
1996 Robbins DC, Andersen L, Bowsher R, Chance R, Dinesen B, Frank B, Gingerich R, Goldstein D, Widemeyer HM, Haffner S, Hales CN, Jarett L, Polonsky K, Porte D, Skyler J, et al. Report of the American Diabetes Asociation's task force on standardization of the insulin assay Diabetes. 45: 242-256. PMID 8549870 DOI: 10.2337/Diab.45.2.242  0.443
1996 O'Meara NM, Sturis J, Herold KC, Ostrega DM, Polonsky KS. Alterations in the patterns of insulin secretion before and after diagnosis of IDDM. Diabetes Care. 18: 568-71. PMID 7497873 DOI: 10.2337/Diacare.18.4.568  0.551
1995 Sturis J, Knudsen C, O'Meara NM, Thomsen JS, Mosekilde E, Van Cauter E, Polonsky KS. Phase-locking regions in a forced model of slow insulin and glucose oscillations. Chaos (Woodbury, N.Y.). 5: 193-199. PMID 12780173 DOI: 10.1063/1.166068  0.443
1995 Frank SA, Roland DC, Sturis J, Byrne MM, Refetoff S, Polonsky KS, Van Cauter E. Effects of aging on glucose regulation during wakefulness and sleep. The American Journal of Physiology. 269: E1006-16. PMID 8572190 DOI: 10.1152/Ajpendo.1995.269.6.E1006  0.534
1995 Byrne MM, Sturis J, Polonsky KS. Insulin secretion and clearance during low-dose graded glucose infusion American Journal of Physiology-Endocrinology and Metabolism. 268. PMID 7840177 DOI: 10.1152/Ajpendo.1995.268.1.E21  0.556
1995 Polonsky KS. Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research. Diabetes. 44: 705-717. PMID 7789637 DOI: 10.2337/Diab.44.6.705  0.605
1995 Byrne MM, Sturis J, Fajans SS, Ortiz FJ, Stoltz A, Stoffel M, Smith MJ, Bell GI, Halter JB, Polonsky KS. Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20. Diabetes. 44: 699-704. PMID 7789636 DOI: 10.2337/Diab.44.6.699  0.571
1995 Ryan EA, Imes SI, Liu D, McManus R, Finegood DT, Polonsky KS, Sturis J. Defects in Insulin Secretion and Action in Women With a History of Gestational Diabetes Diabetes. 44: 506-512. PMID 7729607 DOI: 10.2337/Diab.44.5.506  0.484
1995 Sturis J, Scheen AJ, Leproult R, Polonsky KS, Van Cauter E. 24-hour glucose profiles during continuous or oscillatory insulin infusion: Demonstration of the functional significance of ultradian insulin oscillations Journal of Clinical Investigation. 95: 1464-1471. PMID 7706450 DOI: 10.1172/Jci117817  0.585
1995 Ostrega D, Polonsky K, Nagi D, Yudkin J, Cox LJ, Clark PM, Hales CN. Measurement of proinsulin and intermediates. Validation of immunoassay methods by high-performance liquid chromatography. Diabetes. 44: 437-40. PMID 7698513 DOI: 10.2337/Diab.44.4.437  0.449
1995 Byrne MM, O'Meara JSNM, Polonsky KS. Insulin secretion in insulin-resistant women with a history of gestational diabetes. Metabolism-Clinical and Experimental. 44: 1067-1073. PMID 7637649 DOI: 10.1016/0026-0495(95)90106-X  0.607
1995 Stoffel M, Tokuyama Y, Trabb JB, German MS, Tsaar ML, Jan LY, Polonsky KS, Bell GI. Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. Biochemical and Biophysical Research Communications. 212: 894-9. PMID 7626127 DOI: 10.1006/Bbrc.1995.2053  0.397
1995 Ehrmann DA, Sturis J, Byrne MM, Karrison T, Rosenfield RL, Polonsky KS. Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus. Journal of Clinical Investigation. 96: 520-527. PMID 7615824 DOI: 10.1172/Jci118064  0.569
1995 Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J, Sun X, Polonsky KS, Bell GI. Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes. 44: 1447-57. PMID 7589853 DOI: 10.2337/Diab.44.12.1447  0.573
1995 Sturis J, Pugh WL, Tang J, Polonsky KS. Prevention of diabetes does not completely prevent insulin secretory defects in the ZDF rat. American Journal of Physiology-Endocrinology and Metabolism. 269. PMID 7485496 DOI: 10.1152/Ajpendo.1995.269.4.E786  0.475
1995 O'Rahilly S, Gray H, Humphreys PJ, Krook A, Polonsky KS, White A, Gibson S, Taylor K, Carr C. Brief report: Impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function The New England Journal of Medicine. 333: 1386-1390. PMID 7477119 DOI: 10.1056/Nejm199511233332104  0.581
1994 Herman WH, Fajans SS, Ortiz FJ, Smith MJ, Sturis J, Bell GI, Polonsky KS, Halter JB. Abnormal Insulin Secretion, Not Insulin Resistance, Is the Genetic or Primary Defect of MODY in the RW Pedigree Diabetes. 43: 40-46. PMID 8262315 DOI: 10.2337/Diab.43.1.40  0.606
1994 Sturis J, Kurland IJ, Byrne MM, Mosekilde E, Froguel P, Pilkis SJ, Bell GI, Polonsky KS. Compensation in pancreatic β-cell function in subjects with glucokinase mutations Diabetes. 43: 718-723. PMID 8168650 DOI: 10.2337/Diab.43.5.718  0.515
1994 Kelley DE, Wing R, Buonocore C, Sturis J, Polonsky K, Fitzsimmons M. Relative effects of calorie restriction and weight loss in noninsulin-dependent diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 77: 1287-93. PMID 8077323 DOI: 10.1210/Jcem.77.5.8077323  0.437
1994 Sturis J, Pugh WL, Tang J, Ostrega DM, Polonsky JS, Polonsky KS. Alterations in pulsatile insulin secretion in the Zucker diabetic fatty rat. The American Journal of Physiology. 267: E250-9. PMID 8074204 DOI: 10.1152/Ajpendo.1994.267.2.E250  0.562
1994 Iwashima Y, Kondoh-Abiko A, Seino S, Takeda J, Eto M, Polonsky KS, Makino I. Reduced levels of messenger ribonucleic acid for calcium channel, glucose transporter-2, and glucokinase are associated with alterations in insulin secretion in fasted rats Endocrinology. 135: 1010-1017. PMID 8070343 DOI: 10.1210/Endo.135.3.8070343  0.532
1994 Fajans SS, Bell GI, Bowden DW, Halter JB, Polonsky KS. Maturity-onset diabetes of the young Life Sciences. 55: 413-422. PMID 8035658 DOI: 10.1016/0024-3205(94)90052-3  0.463
1994 Lewis GF, Steiner G, Polonsky KS, Weller B, Zinman B. A new method for comparing portal and peripheral venous insulin delivery in humans: Tolbutamide versus insulin infusion Journal of Clinical Endocrinology and Metabolism. 79: 66-70. PMID 8027255 DOI: 10.1210/Jcem.79.1.8027255  0.587
1994 Polonsky KS, Gumbiner B, Ostrega D, Griver K, Tager H, Henry RR. Alterations in immunoreactive proinsulin and insulin clearance induced by weight loss in NIDDM Diabetes. 43: 871-877. PMID 8013750 DOI: 10.2337/Diab.43.7.871  0.559
1994 Van Cauter E, Polonsky KS, Blackman JD, Roland D, Sturis J, Byrne MM, Scheen AJ. Abnormal temporal patterns of glucose tolerance in obesity: Relationship to sleep-related growth hormone secretion and circadian cortisol rhythmicity Journal of Clinical Endocrinology and Metabolism. 79: 1797-1805. PMID 7989487 DOI: 10.1210/Jcem.79.6.7989487  0.476
1994 Polonsky KS. Oscillatory Insulin Secretion Ifac Proceedings Volumes. 27: 321-322. DOI: 10.1016/S1474-6670(17)46254-9  0.558
1993 O'Meara NM, Blackman JD, Ehrmann DA, Barnes RB, Jaspan JB, Rosenfield RL, Polonsky KS. Defects in beta-cell function in functional ovarian hyperandrogenism. The Journal of Clinical Endocrinology and Metabolism. 76: 1241-7. PMID 8496316 DOI: 10.1210/Jcem.76.5.8496316  0.573
1993 O'Meara NM, Sturis J, Blackman JD, Byrne MM, Jaspan JB, Roland DC, Thistlethwaite JR, Polonsky KS. Oscillatory Insulin Secretion After Pancreas Transplant Diabetes. 42: 855-861. PMID 8495809 DOI: 10.2337/Diab.42.6.855  0.521
1993 Sturis J, O'Meara NM, Shapiro ET, Blackman JD, Tillil H, Polonsky KS, Van Cauter E. Differential effects of glucose stimulation upon rapid pulses and ultradian oscillations of insulin secretion Journal of Clinical Endocrinology and Metabolism. 76: 895-901. PMID 8473402 DOI: 10.1210/Jcem.76.4.8473402  0.547
1993 O'Meara NM, Sturis J, Blackman JD, Roland DC, Van Cauter E, Polonsky KS. Analytical problems in detecting rapid insulin secretory pulses in normal humans American Journal of Physiology - Endocrinology and Metabolism. 264: E231-E238. PMID 8447390 DOI: 10.1152/Ajpendo.1993.264.2.E231  0.495
1993 O'Meara NM, Blackman JD, Sturis J, Polonsky KS. Alterations in the Kinetics of C-Peptide and Insulin Secretion in Hyperthyroidism* The Journal of Clinical Endocrinology and Metabolism. 76: 79-84. PMID 8421108 DOI: 10.1210/Jcem.76.1.8421108  0.564
1993 Reaven GM, Chen Y-I, Hollenbeck CB, Sheu WHH, Ostrega D, Polonsky KS. Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance. The Journal of Clinical Endocrinology and Metabolism. 76: 44-48. PMID 8421101 DOI: 10.1210/Jcem.76.1.8421101  0.59
1993 Levitt NS, Hirsch L, Rubenstein AH, Polonsky KS. Quantitative evaluation of the effect of low-intensity exercise on insulin secretion in man Metabolism. 42: 829-833. PMID 8345793 DOI: 10.1016/0026-0495(93)90054-R  0.637
1993 O'Meara NM, Sturis J, Van Cauter E, Polonsky KS. Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus Journal of Clinical Investigation. 92: 262-271. PMID 8325993 DOI: 10.1172/Jci116560  0.594
1993 Lewis GF, McNally C, Blackman JD, Polonsky KS, Barron WM. Prior feeding Alters the Response to the 50-g Glucose Challenge Test in Pregnancy: The Staub-Traugott Effect revisited Diabetes Care. 16: 1551-1556. PMID 8299450 DOI: 10.2337/Diacare.16.12.1551  0.5
1993 Jeng C-, Sheu WH-, Jaspan JB, Polonsky KS, Chen Y-I, Reaven GM. Glucagon does not increase plasma free fatty acid and glycerol concentrations in patients with noninsulin-dependent diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 77: 6-10. PMID 8100832 DOI: 10.1210/Jcem.77.1.8100832  0.487
1993 Iwashima Y, Pugh W, Depaoli AM, Takeda J, Seino S, Bell GI, Polonsky KS. Expression of Calcium Channel mRNAs in Rat Pancreatic Islets and Downregulation After Glucose Infusion Diabetes. 42: 948-955. PMID 7685720 DOI: 10.2337/Diab.42.7.948  0.435
1992 Sturis J, Polonsky KS, Shapiro ET, Blackman JD, O'Meara NM, Van Cauter E. Abnormalities in the ultradian oscillations of insulin secretion and glucose levels in Type 2 (non-insulin-dependent) diabetic patients Diabetologia. 35: 681-689. PMID 1644248 DOI: 10.1007/Bf00400263  0.588
1992 Yano H, Kitano N, Morimoto M, Polonsky KS, Imura H, Seino Y. A novel point mutation in the human insulin gene giving rise to hyperproinsulinemia (proinsulin Kyoto). Journal of Clinical Investigation. 89: 1902-1907. PMID 1601997 DOI: 10.1172/Jci115795  0.491
1992 Van Cauter E, Shapiro ET, Tillil H, Polonsky KS. Circadian modulation of glucose and insulin responses to meals: Relationship to cortisol rhythm American Journal of Physiology - Endocrinology and Metabolism. 262: E467-E475. PMID 1566835 DOI: 10.1152/Ajpendo.1992.262.4.E467  0.56
1992 Blackman JD, Towle VL, Sturis J, Lewis GF, Spire JP, Polonsky KS. Hypoglycemic thresholds for cognitive dysfunction in IDDM. Diabetes. 41: 392-9. PMID 1551499  0.376
1992 Van Cauter E, Mestrez F, Sturis J, Polonsky KS. Estimation of insulin secretion rates from C-peptide levels: Comparison of individual and standard kinetic parameters for C-peptide clearance Diabetes. 41: 368-377. PMID 1551497 DOI: 10.2337/Diab.41.3.368  0.432
1992 Polonsky KS. A practical approach to fasting hypoglycemia. The New England Journal of Medicine. 326: 1020-1021. PMID 1545839 DOI: 10.1056/Nejm199204093261511  0.382
1992 Blackman JD, Polonsky KS, Jaspan JB, Sturis J, Cauter EV, Thistlethwaite JR. Insulin Secretory Profiles and C-Peptide Clearance Kinetics at 6 Months and 2 Years After Kidney-Pancreas Transplantation Diabetes. 41: 1346-1354. PMID 1397710 DOI: 10.2337/Diab.41.10.1346  0.485
1991 Lewis GF, O'Meara NM, Cabana VG, Blackman JD, Pugh WL, Druetzler AF, Lukens JR, Getz GS, Polonsky KS. Postprandial triglyceride response in Type 1 (insulin-dependent) diabetes mellitus is not altered by short-term deterioration in glycaemic control or level of postprandial insulin replacement Diabetologia. 34: 253-259. PMID 2065859 DOI: 10.1007/Bf00405084  0.526
1991 Herold KC, Polonsky KS. Does tight glucose control enhance brain sensitivity to low glucose? Diabetes Care. 14: 141-3. PMID 2060418 DOI: 10.2337/Diacare.14.2.141  0.445
1991 Sturis J, Polonsky KS, Mosekilde E, Van Cauter E. Computer model for mechanisms underlying ultradian oscillations of insulin and glucose American Journal of Physiology - Endocrinology and Metabolism. 260: E801-E809. PMID 2035636 DOI: 10.1152/Ajpendo.1991.260.5.E801  0.57
1991 Lewis GF, O'Meara NM, Soltys PA, Blackman JD, Iverius PH, Pugh WL, Getz GS, Polonsky KS. Fasting hypertriglyceridemia in noninsulin-dependent diabetes mellitus is an important predictor of postprandial lipid and lipoprotein abnormalities. The Journal of Clinical Endocrinology and Metabolism. 72: 934-44. PMID 2005221 DOI: 10.1210/Jcem-72-4-934  0.346
1991 Sturis J, Van Cauter E, Blackman JD, Polonsky KS. Entrainment of pulsatile insulin secretion by oscillatory glucose infusion Journal of Clinical Investigation. 87: 439-445. PMID 1991830 DOI: 10.1172/Jci115015  0.588
1991 Shapiro ET, Polonsky KS, Copinschi G, Bosson D, Tillil H, Blackman J, Lewis G, Van Cauter E. Nocturnal elevation of glucose levels during fasting in noninsulin-dependent diabetes. The Journal of Clinical Endocrinology and Metabolism. 72: 444-54. PMID 1991813 DOI: 10.1210/Jcem-72-2-444  0.58
1991 Given BD, Ostrega DM, Polonsky KS, Baldwin D, Kelley RI, Rubenstein AH. Hypoglycemia due to surreptitious injection of insulin: Identification of insulin species by high-performance liquid chromatography Diabetes Care. 14: 544-547. PMID 1914793 DOI: 10.2337/Diacare.14.7.544  0.624
1991 Van Cauter E, Blackman JD, Roland D, Spire JP, Refetoff S, Polonsky KS. Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep. The Journal of Clinical Investigation. 88: 934-42. PMID 1885778 DOI: 10.1172/Jci115396  0.5
1990 Gumbiner B, Polonsky KS, Beltz WF, Wallace P, Brechtel G, Fink RI. Effects of aging on insulin secretion. Diabetes. 38: 1549-56. PMID 2684711 DOI: 10.2337/Diab.38.12.1549  0.579
1990 Strack TR, Greenberg GR, Polonsky KS, Albisser AM. The effect of a time delay on the characteristics of the canine glucoregulatory system. Metabolism: Clinical and Experimental. 39: 1219-24. PMID 2246959 DOI: 10.1016/0026-0495(90)90174-B  0.531
1990 Shapiro ET, Cooper M, Chen CT, Given BD, Polonsky KS. Change in Hexose Distribution Volume and Fractional Utilization of [18F]-2-Deoxy-2-Fluoro-D-Glucose in Brain During Acute Hypoglycemia in Humans Diabetes. 39: 175-180. PMID 2227124 DOI: 10.2337/Diab.39.2.175  0.435
1990 Kryshak EJ, Butler PC, Marsh C, Miller A, Barr D, Polonsky K, Perkins JD, Rizza RA. Pattern of Postprandial Carbohydrate Metabolism and Effects of Portal and Peripheral Insulin Delivery Diabetes. 39: 142-148. PMID 2227121 DOI: 10.2337/Diab.39.2.142  0.585
1990 Tillil H, Frank BH, Pekar AH, Broelsch C, Rubenstein AH, Polonsky KS. Hypoglycemic potency and metabolic clearance rate of intravenously administered human proinsulin and metabolites Endocrinology. 127: 2418-2422. PMID 2226325 DOI: 10.1210/Endo-127-5-2418  0.656
1990 Beebe CA, Van Cauter E, Shapiro ET, Tillil H, Lyons R, Rubenstein AH, Polonsky KS. Effect of temporal distribution of calories on diurnal patterns of glucose levels and insulin secretion in NIDDM Diabetes Care. 13: 748-755. PMID 2201497 DOI: 10.2337/Diacare.13.7.748  0.701
1990 Wojcikowski C, Blackman J, Ostrega D, Lewis G, Galloway J, Rubenstein AH, Polonsky KS. Lack of effect of high-dose biosynthetic human C-peptide on pancreatic hormone release in normal subjects Metabolism. 39: 827-832. PMID 2198434 DOI: 10.1016/0026-0495(90)90127-X  0.679
1990 Blackman JD, Towle VL, Lewis GF, Spire JP, Polonsky KS. Hypoglycemic thresholds for cognitive dysfunction in humans. Diabetes. 39: 828-35. PMID 2191886 DOI: 10.2337/Diab.39.7.828  0.438
1990 Gumbiner B, Polonsky KS, Beltz WF, Griver K, Wallace P, Brechtel G, Henry RR. Effects of weight loss and reduced hyperglycemia on the kinetics of insulin secretion in obese non-insulin dependent diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 70: 1594-602. PMID 2189885 DOI: 10.1210/Jcem-70-6-1594  0.573
1990 Shapiro ET, Bell GI, Polonsky KS, Rubenstein AH, Kew MC, Tager HS. Tumor hypoglycemia: relationship to high molecular weight insulin-like growth factor-II. The Journal of Clinical Investigation. 85: 1672-9. PMID 2159026 DOI: 10.1172/Jci114619  0.641
1990 O'Meara NM, Shapiro ET, Van Cauter E, Polonsky KS. Effect of glyburide on beta cell responsiveness to glucose in non-insulin-dependent diabetes mellitus The American Journal of Medicine. 89: S11-S16. DOI: 10.1016/0002-9343(90)90331-7  0.61
1989 Shapiro ET, Van Cauter E, Tillil H, Given BD, Hirsch L, Beebe C, Rubenstein AH, Polonsky KS. Glyburide enhances the responsiveness of the β-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 69: 571-576. PMID 2503533 DOI: 10.1210/Jcem-69-3-571  0.693
1988 Shapiro ET, Tillil H, Polonsky KS, Fang VS, Rubenstein AH, Van Cauter E. Oscillations in insulin secretion during constant glucose infusion in normal man: Relationship to changes in plasma glucose Journal of Clinical Endocrinology and Metabolism. 67: 307-314. PMID 3292558 DOI: 10.1210/Jcem-67-2-307  0.686
1988 Polonsky KS, Given BD, Hirsch LJ, Tillil H, Shapiro ET, Beebe C, Frank BH, Galloway JA, Van Cauter E. Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. The New England Journal of Medicine. 318: 1231-9. PMID 3283554 DOI: 10.1056/Nejm198805123181903  0.568
1988 Tillil H, Shapiro ET, Miller MA, Karrison T, Frank BH, Galloway JA, Rubenstein AH, Polonsky KS. Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans American Journal of Physiology - Gastrointestinal and Liver Physiology. 254: 17/3. PMID 3279811 DOI: 10.1152/Ajpendo.1988.254.3.E349  0.704
1988 Polonsky KS, Given BD, Van Cauter E. Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects Journal of Clinical Investigation. 81: 442-448. PMID 3276730 DOI: 10.1172/Jci113339  0.543
1988 Polonsky KS, Given BD, Hirsch L, Shapiro ET, Tillil H, Beebe C, Galloway JA, Frank BH, Karrison T, Van Cauter E. Quantitative study of insulin secretion and clearance in normal and obese subjects Journal of Clinical Investigation. 81: 435-441. PMID 3276729 DOI: 10.1172/Jci113338  0.541
1988 Kremser CB, Levitt NS, Borow KM, Jaspan JB, Lindbloom C, Polonsky KS, Leff AR. Oxygen uptake kinetics during exercise in diabetic neuropathy. Journal of Applied Physiology. 65: 2665-2671. PMID 3215866 DOI: 10.1152/Jappl.1988.65.6.2665  0.337
1988 Alejandro R, Latif Z, Polonsky KS, Shienvold FL, Civantos F, Mintz DH. Natural history of multiple intrahepatic canine islet allografts during and following administration of cyclosporine Transplantation. 45: 1036-1044. PMID 3132761 DOI: 10.1097/00007890-198806000-00008  0.426
1988 Shapiro ET, Tillil H, Rubenstein AH, Polonsky KS. Peripheral insulin parallels changes in insulin secretion more closely than C-peptide after bolus intravenous glucose administration Journal of Clinical Endocrinology and Metabolism. 67: 1094-1099. PMID 3053748 DOI: 10.1210/Jcem-67-5-1094  0.691
1988 Tillil H, Shapiro ET, Rubenstein AH, Galloway JA, Polonsky KS. Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans Diabetes. 37: 1351-1357. PMID 3046967 DOI: 10.2337/Diab.37.10.1351  0.708
1988 Tillil H, Shapiro ET, Given BD, Rue P, Rubenstein AH, Galloway JA, Polonsky KS. Reevaluation of urine C-peptide as measure of insulin secretion Diabetes. 37: 1195-1201. PMID 3044885 DOI: 10.2337/Diab.37.9.1195  0.669
1987 Nanjo K, Miyano M, Kondo M, Sanke T, Nishimura S, Miyamura K, Inouye K, Given BD, Chan SJ, Polonsky KS, Tager HS, Steiner DF, Rubenstein AH. Insulin Wakayama: familial mutant insulin syndrome in Japan Diabetologia. 30: 87-92. PMID 3552828 DOI: 10.1007/Bf00274577  0.746
1987 Cohen RM, Licinio J, Polonsky KS, Galloway JA, Frank BH, Cherrington AD, Rubenstein AH. The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes Journal of Clinical Endocrinology and Metabolism. 64: 476-481. PMID 3546347 DOI: 10.1210/Jcem-64-3-476  0.696
1987 Shapiro ET, Tillil H, Miller MA, Frank BH, Galloway JA, Rubenstein AH, Polonsky KS. Insulin secretion and clearance. Comparison after oral and intravenous glucose Diabetes. 36: 1365-1371. PMID 3315785 DOI: 10.2337/Diab.36.12.1365  0.679
1987 Volund A, Polonsky KS, Bergman RN. Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics Diabetes. 36: 1195-1202. PMID 2888696 DOI: 10.2337/Diab.36.10.1195  0.508
1986 Shoelson SE, Polonsky KS, Nakabayashi T, Jaspan JB, Tager HS. Circulating forms of somatostatinlike immunoreactivity in human plasma. The American Journal of Physiology. 250: E428-34. PMID 3963183 DOI: 10.1152/Ajpendo.1986.250.4.E428  0.532
1986 Licinio-Paixao J, Polonsky KS, Given BD, Pugh W, Ostrega D, Frank BF, Rubenstein AH. Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide Journal of Clinical Endocrinology and Metabolism. 63: 401-403. PMID 3722329 DOI: 10.1210/Jcem-63-2-401  0.585
1986 Morishima T, Pye S, Polonsky K, Radziuk J. The measurement and validation of the nonsteady-state rates of C-peptide appearance in the dog. Diabetologia. 29: 440-446. PMID 3527843 DOI: 10.1007/Bf00506536  0.345
1986 Polonsky KS, Rubenstein AH. Current approaches to measurement of insulin secretion Diabetes/Metabolism Reviews. 2: 315-329. PMID 3527618 DOI: 10.1002/Dmr.5610020306  0.635
1986 Polonsky KS, Given BD, Pugh W, Licinio-Paixao J, Thompson JE, Karrison T, Rubenstein AH. Calculation of the systemic delivery rate of insulin in normal man Journal of Clinical Endocrinology and Metabolism. 63: 113-118. PMID 3519643 DOI: 10.1210/Jcem-63-1-113  0.654
1986 Polonsky K, Frank B, Pugh W, Addis A, Karrison T, Meier P, Tager H, Rubenstein A. The limitations to and valid use of C-peptide as a marker of the secretion of insulin Diabetes. 35: 379-386. PMID 3514322 DOI: 10.2337/Diab.35.4.379  0.605
1986 Polonsky KS, Licinio-Paixao J, Given BD, Pugh W, Rue P, Galloway J, Karrison T, Frank B. Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients. The Journal of Clinical Investigation. 77: 98-105. PMID 3511094 DOI: 10.1172/Jci112308  0.441
1986 Alejandro R, Cutfield RG, Shienvold FL, Polonsky KS, Noel J, Olson L, Dillberger J, Miller J, Mintz DH. Natural history of intrahepatic canine islet cell autografts Journal of Clinical Investigation. 78: 1339-1348. PMID 3095376 DOI: 10.1172/Jci112720  0.418
1986 Cohen RM, Given BD, Licinio-Paixao J, Provow SA, Rue PA, Frank BH, Root MA, Polonsky KS, Tager HS, Rubenstein AH. Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia. Metabolism: Clinical and Experimental. 35: 1137-46. PMID 3023795 DOI: 10.1016/0026-0495(86)90027-2  0.676
1986 Stagner J, Samols E, Polonsky K, Pugh W. Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas Journal of Clinical Investigation. 78: 1193-1198. PMID 2877010 DOI: 10.1172/Jci112702  0.575
1986 Jaspan JB, Lever E, Polonsky KS, Van Cauter E. In vivo pulsatility of pancreatic islet peptides American Journal of Physiology - Endocrinology and Metabolism. 251: 14/2. PMID 2874743 DOI: 10.1152/Ajpendo.1986.251.2.E215  0.523
1985 Herold KC, Polonsky KS, Cohen RM, Levy J, Douglas F. Variable deterioration in cortical function during insulin-induced hypoglycemia. Diabetes. 34: 677-85. PMID 3891475 DOI: 10.2337/Diab.34.7.677  0.484
1985 Cutfield RG, Polonsky K, Olson L, Kyriakides G, Miller J, Mintz DH. Long-term follow-up of canine segmental pancreatic autografts. Diabetes. 34: 174-178. PMID 2857144 DOI: 10.2337/Diab.34.2.174  0.344
1984 Polonsky KS, Pugh W, Jaspan JB, Cohen DM, Karrison T, Tager HS, Rubenstein AH. C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog. The Journal of Clinical Investigation. 74: 1821-9. PMID 6389599 DOI: 10.1172/Jci111601  0.669
1984 Polonsky KS, Herold KC, Gilden JL, Bergenstal RM, Fang VS, Moossa AR, Jaspan JB. Glucose counterregulation in patients after pancreatectomy. Comparison with other clinical forms of diabetes. Diabetes. 33: 1112-9. PMID 6389228 DOI: 10.2337/Diab.33.11.1112  0.485
1984 Revers RR, Henry R, Schmeiser L, Kolterman O, Cohen R, Bergenstal R, Polonsky K, Jaspan J, Rubenstein A, Frank B. The effects of biosynthetic human proinsulin on carbohydrate metabolism Diabetes. 33: 762-770. PMID 6378699 DOI: 10.2337/Diab.33.8.762  0.686
1984 Bergenstal RM, Cohen RM, Lever E, Polonsky K, Jaspan J, Blix PM, Revers R, Olefsky JM, Kolterman O, Steiner K, Cherrington A, Frank B, Galloway J, Rubenstein AH. The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes. The Journal of Clinical Endocrinology and Metabolism. 58: 973-979. PMID 6373814 DOI: 10.1210/Jcem-58-6-973  0.585
1984 Polonsky KS, Rubenstein AH. C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations Diabetes. 33: 486-494. PMID 6373457 DOI: 10.2337/Diab.33.5.486  0.672
1984 Haneda M, Polonsky KS, Bergenstal RM, Jaspan JB, Shoelson SE, Blix PM, Chan SJ, Kwok SC, Wishner WB, Zeidler A. Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome. The New England Journal of Medicine. 310: 1288-94. PMID 6371526 DOI: 10.1056/NEJM198405173102004  0.713
1984 Shoelson SE, Polonsky KS, Zeidler A, Rubenstein AH, Tager HS. Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model. The Journal of Clinical Investigation. 73: 1351-8. PMID 6371057 DOI: 10.1172/Jci111338  0.811
1984 Cohen DM, Jaspan JB, Polonsky KS, Lever EG, Moossa A. Pancreatic hormone profiles and metabolism posthepatectomy in the dog Gastroenterology. 87: 679-687. DOI: 10.1016/0016-5085(84)90543-2  0.516
1983 Hagopian W, Lever EG, Cohen D, Emmanouel D, Polonsky KS, Pugh W, Moossa A, Jaspan JB. Predominance of renal and absence of hepatic metabolism of pancreatic polypeptide in the dog American Journal of Physiology-Endocrinology and Metabolism. 245. PMID 6881330 DOI: 10.1152/Ajpendo.1983.245.2.E171  0.336
1983 Bergenstal RM, Polonsky KS, Pons G, Jaspan JB, Rubenstein AH. Lack of glucagon response to hypoglycemia in type I diabetics after long-term optimal therapy with a continuous subcutaneous insulin infusion pump. Diabetes. 32: 398-402. PMID 6840400  0.632
1983 Judzewitsch RG, Jaspan JB, Polonsky KS, Weinberg CR, Halter JB, Halar E, Pfeifer MA, Vukadinovic C, Bernstein L, Schneider M, Liang KY, Gabbay KH, Rubenstein AH, Porte D. Aldose reductase inhibition improves nerve conduction velocity in diabetic patients. The New England Journal of Medicine. 308: 119-25. PMID 6401351 DOI: 10.1056/Nejm198301203080302  0.467
1983 Polonsky K, Jaspan J, Pugh W, Cohen D, Schneider M, Schwartz T, Moossa AR, Tager H, Rubenstein AH. Metabolism of C-peptide in the dog. In vivo demonstration of the absence of hepatic extraction. The Journal of Clinical Investigation. 72: 1114-23. PMID 6350363 DOI: 10.1172/Jci111036  0.61
1983 Polonsky K, Jaspan J, Emmanouel D, Holmes K, Moossa AR. Differences in the hepatic and renal extraction of insulin and glucagon in the dog: evidence for saturability of insulin metabolism. European Journal of Endocrinology. 102: 420-427. PMID 6338678 DOI: 10.1530/Acta.0.1020420  0.496
1983 Polonsky KS, Shoelson SE, Docherty HM. Plasma somatostatin 28 increases in response to feeding in man. The Journal of Clinical Investigation. 71: 1514-8. PMID 6133883 DOI: 10.1172/Jci110907  0.565
1982 Polonsky K, Bergenstal R, Pons G, Schneider M, Jaspan J, Rubenstein A. Relation of counterregulatory responses to hypoglycemia in Type I diabetics New England Journal of Medicine. 307: 1106-1112. PMID 7121528 DOI: 10.1056/Nejm198210283071802  0.64
1982 Jaspan J, Polonsky K. Glucose ingestion in dogs alters the hepatic extraction of insulin. In vivo evidence for a relationship between biologic action and extraction of insulin. Journal of Clinical Investigation. 69: 516-525. PMID 7037850 DOI: 10.1172/Jci110477  0.56
1982 Bonnevie-Nielsen V, Polonsky KS, Jaspan JJ, Rubenstein AH, Schwartz TW, Tager HS. Surface receptors for pancreatic hormones in dog and rat hepatocytes: qualitative and quantitative differences in hormone-target cell interactions. Proceedings of the National Academy of Sciences of the United States of America. 79: 2167-71. PMID 6285368 DOI: 10.1073/Pnas.79.7.2167  0.495
1982 Shoelson S, Polonsky K, Docherty H, Jaspan J, Rubenstein A. Evidence for the presence of somatostatin 28 in plasma Diabetes. 31: 474-477. PMID 6130021 DOI: 10.2337/Diab.31.5.474  0.625
1981 Jaspan JB, Polonsky KS, Röjdmark S, Ishida T, Field JB, Rubenstein AH. Hepatic extraction of plasma immunoreactive glucagon components. Predilection for 3500-dalton glucagon metabolism by the liver. Diabetes. 30: 767-72. PMID 7262472 DOI: 10.2337/Diab.30.9.767  0.474
1981 Jaspan JB, Polonsky KS, Lewis M, Pensler J, Pugh W, Moossa AR, Rubenstein AH. Hepatic metabolism of glucagon in the dog: contribution of the liver to overall metabolic disposal of glucagon. The American Journal of Physiology. 240: E233-44. PMID 7011049 DOI: 10.1152/Ajpendo.1981.240.3.E233  0.486
1981 Polonsky K, Jaspan J, Pugh W, Dhorajiwala J, Abraham M, Blix P, Moossa AR. Insulin and glucagon breakthrough of somatostatin suppression: importance of portal vein hormone measurements. Diabetes. 30: 664-9. PMID 6114006 DOI: 10.2337/diab.30.8.664  0.427
1981 Stacpoole PW, Jaspan J, Kasselberg AG, Halter SA, Polonsky K, Gluck FW, Liljenquist JE, Rabin D. A familial glucagonoma syndrome: genetic, clinical and biochemical features. The American Journal of Medicine. 70: 1017-1026. PMID 6112877 DOI: 10.1016/0002-9343(81)90858-5  0.478
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