| Year |
Citation |
Score |
| 2023 |
Singh V, Menard MA, Serrano GE, Beach TG, Zhao HT, Riley-DiPaolo A, Subrahmanian N, LaVoie MJ, Volpicelli-Daley LA. Cellular and subcellular localization of Rab10 and phospho-T73 Rab10 in the mouse and human brain. Acta Neuropathologica Communications. 11: 201. PMID 38110990 DOI: 10.1186/s40478-023-01704-9 |
0.301 |
|
| 2020 |
Lee H, Fenster RJ, Pineda SS, Gibbs WS, Mohammadi S, Davila-Velderrain J, Garcia FJ, Therrien M, Novis HS, Gao F, Wilkinson H, Vogt T, Kellis M, LaVoie MJ, Heiman M. Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation. Neuron. PMID 32681824 DOI: 10.1016/J.Neuron.2020.06.021 |
0.32 |
|
| 2020 |
Sanyal A, Novis HS, Gasser E, Lin S, LaVoie MJ. LRRK2 Kinase Inhibition Rescues Deficits in Lysosome Function Due to Heterozygous Expression in Human iPSC-Derived Neurons. Frontiers in Neuroscience. 14: 442. PMID 32499675 DOI: 10.3389/Fnins.2020.00442 |
0.396 |
|
| 2020 |
Sanyal A, DeAndrade MP, Novis HS, Lin S, Chang J, Lengacher N, Tomlinson JJ, Tansey MG, LaVoie MJ. Lysosome and Inflammatory Defects in GBA1-Mutant Astrocytes Are Normalized by LRRK2 Inhibition. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32034799 DOI: 10.1002/Mds.27994 |
0.35 |
|
| 2018 |
Amin P, Florez M, Najafov A, Pan H, Geng J, Ofengeim D, Dziedzic SA, Wang H, Barrett VJ, Ito Y, LaVoie MJ, Yuan J. Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29891719 DOI: 10.1073/Pnas.1806973115 |
0.398 |
|
| 2017 |
Schapansky J, Khasnavis S, DeAndrade MP, Nardozzi JD, Falkson SR, Boyd JD, Sanderson JB, Bartels T, Melrose HL, LaVoie MJ. Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons. Neurobiology of Disease. PMID 29246723 DOI: 10.1016/J.Nbd.2017.12.005 |
0.376 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Lavoie MJ, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886 |
0.475 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... LaVoie MJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.536 |
|
| 2015 |
Charan RA, LaVoie MJ. Pathologic and therapeutic implications for the cell biology of parkin. Molecular and Cellular Neurosciences. 66: 62-71. PMID 25697646 DOI: 10.1016/J.Mcn.2015.02.008 |
0.367 |
|
| 2014 |
Schapansky J, Nardozzi JD, LaVoie MJ. The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease. Neuroscience. PMID 25284317 DOI: 10.1016/J.Neuroscience.2014.09.049 |
0.428 |
|
| 2014 |
Renella R, Schlehe JS, Selkoe DJ, Williams DA, LaVoie MJ. Genetic deletion of the GATA1-regulated protein α-synuclein reduces oxidative stress and nitric oxide synthase levels in mature erythrocytes. American Journal of Hematology. 89: 974-7. PMID 25043722 DOI: 10.1002/Ajh.23796 |
0.477 |
|
| 2014 |
Charan RA, Johnson BN, Zaganelli S, Nardozzi JD, LaVoie MJ. Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin. Cell Death & Disease. 5: e1313. PMID 24991765 DOI: 10.1038/Cddis.2014.278 |
0.385 |
|
| 2014 |
Schapansky J, Nardozzi JD, Felizia F, LaVoie MJ. Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy. Human Molecular Genetics. 23: 4201-14. PMID 24682598 DOI: 10.1093/Hmg/Ddu138 |
0.422 |
|
| 2013 |
Schlehe JS, Journel MS, Taylor KP, Amodeo KD, LaVoie MJ. The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress. Neurobiology of Disease. 58: 57-67. PMID 23702311 DOI: 10.1016/J.Nbd.2013.05.007 |
0.387 |
|
| 2012 |
Johnson BN, Charan RA, LaVoie MJ. Recognizing the cooperative and independent mitochondrial functions of Parkin and PINK1. Cell Cycle (Georgetown, Tex.). 11: 2775-6. PMID 22801534 DOI: 10.4161/Cc.21261 |
0.327 |
|
| 2012 |
Johnson BN, Berger AK, Cortese GP, Lavoie MJ. The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax. Proceedings of the National Academy of Sciences of the United States of America. 109: 6283-8. PMID 22460798 DOI: 10.1073/Pnas.1113248109 |
0.392 |
|
| 2011 |
Wang X, Winter D, Ashrafi G, Schlehe J, Wong YL, Selkoe D, Rice S, Steen J, LaVoie MJ, Schwarz TL. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell. 147: 893-906. PMID 22078885 DOI: 10.1016/J.Cell.2011.10.018 |
0.468 |
|
| 2011 |
Bosco DA, LaVoie MJ, Petsko GA, Ringe D. Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis. Cold Spring Harbor Perspectives in Biology. 3: a007500. PMID 21844169 DOI: 10.1101/Cshperspect.A007500 |
0.364 |
|
| 2011 |
Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, LaVoie MJ, Gris D, Park DS, Angel JB, Shen J, et al. Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 795-808. PMID 21552986 DOI: 10.1007/S00702-011-0653-2 |
0.348 |
|
| 2010 |
Berger Z, Smith KA, Lavoie MJ. Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation. Biochemistry. 49: 5511-23. PMID 20515039 DOI: 10.1021/Bi100157U |
0.437 |
|
| 2010 |
Chen AC, Guo LY, Ostaszewski BL, Selkoe DJ, LaVoie MJ. Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substrates. The Journal of Biological Chemistry. 285: 11378-91. PMID 20145246 DOI: 10.1074/Jbc.M109.088815 |
0.686 |
|
| 2009 |
Venderova K, Kabbach G, Abdel-Messih E, Zhang Y, Parks RJ, Imai Y, Gehrke S, Ngsee J, Lavoie MJ, Slack RS, Rao Y, Zhang Z, Lu B, Haque ME, Park DS. Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease. Human Molecular Genetics. 18: 4390-404. PMID 19692353 DOI: 10.1093/Hmg/Ddp394 |
0.396 |
|
| 2009 |
Berger AK, Cortese GP, Amodeo KD, Weihofen A, Letai A, LaVoie MJ. Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release. Human Molecular Genetics. 18: 4317-28. PMID 19679562 DOI: 10.1093/Hmg/Ddp384 |
0.36 |
|
| 2009 |
Rappley I, Myers DS, Milne SB, Ivanova PT, Lavoie MJ, Brown HA, Selkoe DJ. Lipidomic profiling in mouse brain reveals differences between ages and genders, with smaller changes associated with alpha-synuclein genotype. Journal of Neurochemistry. 111: 15-25. PMID 19627450 DOI: 10.1111/J.1471-4159.2009.06290.X |
0.667 |
|
| 2009 |
Rappley I, Gitler AD, Selvy PE, LaVoie MJ, Levy BD, Brown HA, Lindquist S, Selkoe DJ. Evidence that alpha-synuclein does not inhibit phospholipase D. Biochemistry. 48: 1077-83. PMID 19146388 DOI: 10.1021/Bi801871H |
0.691 |
|
| 2007 |
LaVoie MJ, Cortese GP, Ostaszewski BL, Schlossmacher MG. The effects of oxidative stress on parkin and other E3 ligases. Journal of Neurochemistry. 103: 2354-68. PMID 17883392 DOI: 10.1111/J.1471-4159.2007.04911.X |
0.41 |
|
| 2005 |
Fraering PC, Ye W, LaVoie MJ, Ostaszewski BL, Selkoe DJ, Wolfe MS. gamma-Secretase substrate selectivity can be modulated directly via interaction with a nucleotide-binding site. The Journal of Biological Chemistry. 280: 41987-96. PMID 16236717 DOI: 10.1074/Jbc.M501368200 |
0.565 |
|
| 2005 |
LaVoie MJ, Ostaszewski BL, Weihofen A, Schlossmacher MG, Selkoe DJ. Dopamine covalently modifies and functionally inactivates parkin. Nature Medicine. 11: 1214-21. PMID 16227987 DOI: 10.1038/Nm1314 |
0.518 |
|
| 2004 |
Baulac S, LaVoie MJ, Strahle J, Schlossmacher MG, Xia W. Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain. Molecular and Cellular Neurosciences. 27: 236-46. PMID 15519239 DOI: 10.1016/J.Mcn.2004.06.014 |
0.399 |
|
| 2004 |
Fraering PC, Ye W, Strub JM, Dolios G, LaVoie MJ, Ostaszewski BL, van Dorsselaer A, Wang R, Selkoe DJ, Wolfe MS. Purification and characterization of the human gamma-secretase complex. Biochemistry. 43: 9774-89. PMID 15274632 DOI: 10.1021/Bi0494976 |
0.593 |
|
| 2004 |
Fraering PC, LaVoie MJ, Ye W, Ostaszewski BL, Kimberly WT, Selkoe DJ, Wolfe MS. Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex. Biochemistry. 43: 323-33. PMID 14717586 DOI: 10.1021/Bi035748J |
0.711 |
|
| 2004 |
Selkoe DJ, LaVoie M, Fraering P, Ostaszewski B, Ye W, Zheng B, Taylor Kimberly W, Wolfe M. S2-03-01 Presenilin as the active site of gamma-secretase, a novel intramembranous aspartyl protease Neurobiology of Aging. 25: S28. DOI: 10.1016/S0197-4580(04)80091-5 |
0.5 |
|
| 2003 |
Baulac S, LaVoie MJ, Kimberly WT, Strahle J, Wolfe MS, Selkoe DJ, Xia W. Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates. Neurobiology of Disease. 14: 194-204. PMID 14572442 DOI: 10.1016/S0969-9961(03)00123-2 |
0.715 |
|
| 2003 |
LaVoie MJ, Fraering PC, Ostaszewski BL, Ye W, Kimberly WT, Wolfe MS, Selkoe DJ. Assembly of the gamma-secretase complex involves early formation of an intermediate subcomplex of Aph-1 and nicastrin. The Journal of Biological Chemistry. 278: 37213-22. PMID 12857757 DOI: 10.1074/Jbc.M303941200 |
0.71 |
|
| 2003 |
LaVoie MJ, Selkoe DJ. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments. The Journal of Biological Chemistry. 278: 34427-37. PMID 12826675 DOI: 10.1074/Jbc.M302659200 |
0.546 |
|
| 2003 |
Walsh DM, Fadeeva JV, LaVoie MJ, Paliga K, Eggert S, Kimberly WT, Wasco W, Selkoe DJ. gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry. 42: 6664-73. PMID 12779321 DOI: 10.1021/Bi027375C |
0.731 |
|
| 2003 |
Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS, Selkoe DJ. Gamma-secretase is a membrane protein complex comprised of presenilin, nicastrin, Aph-1, and Pen-2. Proceedings of the National Academy of Sciences of the United States of America. 100: 6382-7. PMID 12740439 DOI: 10.1073/Pnas.1037392100 |
0.727 |
|
| 2002 |
Kimberly WT, LaVoie MJ, Ostaszewski BL, Ye W, Wolfe MS, Selkoe DJ. Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular regulation. The Journal of Biological Chemistry. 277: 35113-7. PMID 12130643 DOI: 10.1074/Jbc.M204446200 |
0.708 |
|
| 2001 |
Silflow CD, Lavoie M, Tam LW, Tousey S, Sanders M, Wu WC, Borodovsky M, Lefebvre PA. The Vfl1 protein in Chlamydomonas localizes in a rotationally asymmetric pattern at the distal ends of the basal bodies Journal of Cell Biology. 153: 63-74. PMID 11285274 DOI: 10.1083/Jcb.153.1.63 |
0.307 |
|
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