Joachim Frank - Publications

Affiliations: 
Biochemistry and Molecular Biophysics Columbia University, New York, NY 
Area:
cryo-electron microscopy (cryo-EM) of ribosomes
Website:
http://biochemistry.hs.columbia.edu/faculty/joachim.html

308 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Park J, Zuo H, Frangaj A, Fu Z, Yen LY, Zhang Z, Mosyak L, Slavkovich VN, Liu J, Ray KM, Cao B, Vallese F, Geng Y, Chen S, Grassucci R, ... ... Frank J, et al. Symmetric activation and modulation of the human calcium-sensing receptor. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34916296 DOI: 10.1073/pnas.2115849118  0.724
2020 Dashti A, Mashayekhi G, Shekhar M, Ben Hail D, Salah S, Schwander P, des Georges A, Singharoy A, Frank J, Ourmazd A. Retrieving functional pathways of biomolecules from single-particle snapshots. Nature Communications. 11: 4734. PMID 32948759 DOI: 10.1038/S41467-020-18403-X  0.768
2020 Washburn RS, Zuber PK, Sun M, Hashem Y, Shen B, Li W, Harvey S, Acosta Reyes FJ, Gottesman ME, Knauer SH, Frank J. Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience. 23: 101352. PMID 32726726 DOI: 10.1016/J.Isci.2020.101352  0.381
2020 Park J, Fu Z, Frangaj A, Liu J, Mosyak L, Shen T, Slavkovich VN, Ray KM, Taura J, Cao B, Geng Y, Zuo H, Kou Y, Grassucci R, Chen S, ... ... Frank J, et al. Author Correction: Structure of human GABA receptor in an inactive state. Nature. PMID 32665714 DOI: 10.1038/S41586-020-2543-Y  0.727
2020 Park J, Fu Z, Frangaj A, Liu J, Mosyak L, Shen T, Slavkovich VN, Ray KM, Taura J, Cao B, Geng Y, Zuo H, Kou Y, Grassucci R, Chen S, ... ... Frank J, et al. Structure of human GABA receptor in an inactive state. Nature. PMID 32581365 DOI: 10.1038/S41586-020-2452-0  0.747
2020 Zheng X, Fu Z, Su D, Zhang Y, Li M, Pan Y, Li H, Li S, Grassucci RA, Ren Z, Hu Z, Li X, Zhou M, Li G, Frank J, et al. Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nature Structural & Molecular Biology. PMID 32483338 DOI: 10.1038/S41594-020-0433-5  0.749
2020 Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, ... ... Frank J, et al. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Science Advances. 6: eaay9572. PMID 32270040 DOI: 10.1126/Sciadv.Aay9572  0.774
2019 Acosta-Reyes F, Neupane R, Frank J, Fernández IS. The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. The Embo Journal. e102226. PMID 31609474 DOI: 10.15252/Embj.2019102226  0.364
2019 Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M, Chen B, Grassucci RA, Ehrenberg M, Frank J. The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nature Communications. 10: 2579. PMID 31189921 DOI: 10.1016/J.Bpj.2018.11.3090  0.774
2019 Kaledhonkar S, Fu Z, Caban K, Li W, Chen B, Sun M, Gonzalez RL, Frank J. Late steps in bacterial translation initiation visualized using time-resolved cryo-EM. Nature. PMID 31108498 DOI: 10.1038/S41586-019-1249-5  0.763
2018 Qiu W, Fu Z, Xu GG, Grassucci RA, Zhang Y, Frank J, Hendrickson WA, Guo Y. Structure and activity of lipid bilayer within a membrane-protein transporter. Proceedings of the National Academy of Sciences of the United States of America. 115: 12985-12990. PMID 30509977 DOI: 10.1073/pnas.1812526115  0.744
2018 Gerbasi VR, Browne CM, Samir P, Shen B, Sun M, Hazelbaker DZ, Galassie AC, Frank J, Link AJ. Critical Role for Saccharomyces cerevisiae Asc1p in Translational Initiation at Elevated Temperatures. Proteomics. e1800208. PMID 30285306 DOI: 10.1002/Pmic.201800208  0.326
2018 Wang J, Liu Z, Crabtree RH, Frank J, Moore PB. On the damage done to the structure of the T. acidophilum proteasome by electron radiation. Protein Science : a Publication of the Protein Society. PMID 30242932 DOI: 10.1002/Pro.3511  0.336
2018 Samir P, Brown CM, Rahul R, Sun M, Shen B, Li W, Frank J, Link AJ. Identification of Changing Ribosome Protein Compositions using Mass Spectrometry. Proteomics. e1800217. PMID 30211483 DOI: 10.1002/Pmic.201800217  0.304
2018 Frank J. Single-Particle Reconstruction of Biological Molecules-Story in a Sample (Nobel Lecture). Angewandte Chemie (International Ed. in English). PMID 29978534 DOI: 10.1002/Anie.201802770  0.318
2018 Jobe A, Liu Z, Gutierrez-Vargas C, Frank J. New Insights into Ribosome Structure and Function. Cold Spring Harbor Perspectives in Biology. PMID 29903714 DOI: 10.1101/Cshperspect.A032615  0.369
2018 Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S, Ehrenberg M, Frank J. Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Research. PMID 29733411 DOI: 10.1093/Nar/Gky346  0.359
2018 Kaledhonkar S, Fu Z, White H, Frank J. Time-Resolved Cryo-electron Microscopy Using a Microfluidic Chip. Methods in Molecular Biology (Clifton, N.J.). 1764: 59-71. PMID 29605908 DOI: 10.1007/978-1-4939-7759-8_4  0.759
2018 Hashem Y, Frank J. The Jigsaw Puzzle of mRNA Translation Initiation in Eukaryotes: A Decade of Structures Unraveling the Mechanics of the Process. Annual Review of Biophysics. PMID 29494255 DOI: 10.1146/Annurev-Biophys-070816-034034  0.331
2018 Santulli G, Lewis D, des Georges A, Marks AR, Frank J. Ryanodine Receptor Structure and Function in Health and Disease. Sub-Cellular Biochemistry. 87: 329-352. PMID 29464565 DOI: 10.1007/978-981-10-7757-9_11  0.75
2018 Caban K, Pavlov M, Kaledhonkar S, Fu Z, Frank J, Ehrenberg M, Gonzalez RL. The Structural Basis for Initiation Factor 2 Activation during Translation Initiation Biophysical Journal. 114: 593a. DOI: 10.1016/J.Bpj.2017.11.3243  0.749
2018 Qiu W, Fu Z, Xu G, Grassucci RA, Hendrickson WA, Zhang Y, Frank J, Guo Y. Lipid Bilayer Structure in Native Cell Membrane Nanoparticles of Multidrug Exporter ACRB Biophysical Journal. 114: 369a-370a. DOI: 10.1016/J.Bpj.2017.11.2048  0.722
2017 Twomey EC, Yelshanskaya MV, Grassucci RA, Frank J, Sobolevsky AI. Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature. PMID 28737760 DOI: 10.1038/Nature23479  0.773
2017 Frank J. Time-resolved Cryo-Electron Microscopy: Recent Progress. Journal of Structural Biology. PMID 28625887 DOI: 10.1016/J.Jsb.2017.06.005  0.332
2017 Twomey EC, Yelshanskaya MV, Grassucci RA, Frank J, Sobolevsky AI. Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron. 94: 569-580.e5. PMID 28472657 DOI: 10.1016/J.Neuron.2017.04.025  0.802
2017 Frank J. The mechanism of translation. F1000research. 6: 198. PMID 28344776 DOI: 10.12688/F1000Research.9760.1  0.372
2017 Feng X, Fu Z, Kaledhonkar S, Jia Y, Shah B, Jin A, Liu Z, Sun M, Chen B, Grassucci RA, Ren Y, Jiang H, Frank J, Lin Q. A Fast and Effective Microfluidic Spraying-Plunging Method for High-Resolution Single-Particle Cryo-EM. Structure (London, England : 1993). PMID 28286002 DOI: 10.1016/J.Str.2017.02.005  0.745
2017 Maji S, Shahoei R, Schulten K, Frank J. Quantitative Characterization of Domain Motions in Molecular Machines. The Journal of Physical Chemistry. B. PMID 28199113 DOI: 10.1021/Acs.Jpcb.6B10732  0.453
2017 Malyutin AG, Musalgaonkar S, Patchett S, Frank J, Johnson AW. Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis. The Embo Journal. PMID 28179369 DOI: 10.15252/Embj.201696012  0.398
2017 Frank J. The translation elongation cycle-capturing multiple states by cryo-electron microscopy. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 28138066 DOI: 10.1098/Rstb.2016.0180  0.377
2017 Frank J. Advances in the field of single-particle cryo-electron microscopy over the last decade. Nature Protocols. 12: 209-212. PMID 28055037 DOI: 10.1038/Nprot.2017.004  0.358
2017 Georges Ad, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J. Functional Study of the Ryanodine Receptor Type 1 using Cryo-Electron Microscopy Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1813  0.386
2016 Fu Z, Kaledhonkar S, Borg A, Sun M, Chen B, Grassucci RA, Ehrenberg M, Frank J. Key Intermediates in Ribosome Recycling Visualized by Time-Resolved Cryoelectron Microscopy. Structure (London, England : 1993). PMID 27818103 DOI: 10.1016/J.Str.2016.09.014  0.778
2016 Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA, Ramesh M, Espina N, Sun M, Tutuncuoglu B, Madison-Antenucci S, Woolford JL, Tong L, Frank J. Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit. Proceedings of the National Academy of Sciences of the United States of America. 113: 12174-12179. PMID 27791004 DOI: 10.1073/Pnas.1614594113  0.391
2016 Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA, Espina N, Madison-Antenucci S, Tong L, Frank J. Determination of the ribosome structure to a resolution of 2.5 Å by single-particle cryo-EM. Protein Science : a Publication of the Protein Society. PMID 27750394 DOI: 10.1002/Pro.3068  0.365
2016 des Georges A, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J. Structural Basis for Gating and Activation of RyR1. Cell. 167: 145-157.e17. PMID 27662087 DOI: 10.1016/J.Cell.2016.08.075  0.757
2016 Chen Y, Clarke OB, Kim J, Stowe S, Kim YK, Assur Z, Cavalier M, Godoy-Ruiz R, von Alpen DC, Manzini C, Blaner WS, Frank J, Quadro L, Weber DJ, Shapiro L, et al. Structure of the STRA6 receptor for retinol uptake. Science (New York, N.Y.). 353. PMID 27563101 DOI: 10.1126/Science.Aad8266  0.344
2016 Twomey EC, Yelshanskaya MV, Grassucci RA, Frank J, Sobolevsky AI. Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy. Science (New York, N.Y.). 353: 83-6. PMID 27365450 DOI: 10.1126/Science.Aaf8411  0.797
2016 Frank J. Whither ribosome structure and dynamics research? (A Perspective). Journal of Molecular Biology. PMID 27178840 DOI: 10.1016/J.Jmb.2016.04.034  0.357
2016 Frank J, Ourmazd A. Continuous Changes in Structure Mapped by Manifold Embedding of Single-Particle Data in Cryo-EM. Methods (San Diego, Calif.). PMID 26884261 DOI: 10.1016/J.Ymeth.2016.02.007  0.375
2015 Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD, Frank J. Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Research. PMID 26432834 DOI: 10.1093/Nar/Gkv991  0.348
2015 des Georges A, Dhote V, Kuhn L, Hellen CU, Pestova TV, Frank J, Hashem Y. Structure of mammalian eIF3 in the context of the 43S preinitiation complex. Nature. 525: 491-5. PMID 26344199 DOI: 10.1038/Nature14891  0.79
2015 Li W, Liu Z, Koripella RK, Langlois R, Sanyal S, Frank J. Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G. Science Advances. 1. PMID 26229983 DOI: 10.1126/Sciadv.1500169  0.362
2015 Chen B, Kaledhonkar S, Sun M, Shen B, Lu Z, Barnard D, Lu TM, Gonzalez RL, Frank J. Structural dynamics of ribosome subunit association studied by mixing-spraying time-resolved cryogenic electron microscopy. Structure (London, England : 1993). 23: 1097-105. PMID 26004440 DOI: 10.1016/J.Str.2015.04.007  0.374
2015 Liao HY, Hashem Y, Frank J. Efficient estimation of three-dimensional covariance and its application in the analysis of heterogeneous samples in cryo-electron microscopy. Structure (London, England : 1993). 23: 1129-37. PMID 25982529 DOI: 10.1016/J.Str.2015.04.004  0.365
2015 Marabini R, Carragher B, Chen S, Chen J, Cheng A, Downing KH, Frank J, Grassucci RA, Bernard Heymann J, Jiang W, Jonic S, Liao HY, Ludtke SJ, Patwari S, Piotrowski AL, et al. CTF Challenge: Result summary. Journal of Structural Biology. 190: 348-59. PMID 25913484 DOI: 10.1016/J.Jsb.2015.04.003  0.778
2015 Kinz-Thompson CD, Sharma AK, Frank J, Gonzalez RL, Chowdhury D. Quantitative Connection between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryogenic Electron Microscopy and Single-Molecule Fluorescence Resonance Energy Transfer Investigations of the Ribosome. The Journal of Physical Chemistry. B. PMID 25785884 DOI: 10.1021/Jp5128805  0.311
2015 Zalk R, Clarke OB, des Georges A, Grassucci RA, Reiken S, Mancia F, Hendrickson WA, Frank J, Marks AR. Structure of a mammalian ryanodine receptor. Nature. 517: 44-9. PMID 25470061 DOI: 10.1038/Nature13950  0.76
2014 Dashti A, Schwander P, Langlois R, Fung R, Li W, Hosseinizadeh A, Liao HY, Pallesen J, Sharma G, Stupina VA, Simon AE, Dinman JD, Frank J, Ourmazd A. Trajectories of the ribosome as a Brownian nanomachine. Proceedings of the National Academy of Sciences of the United States of America. 111: 17492-7. PMID 25422471 DOI: 10.1073/Pnas.1419276111  0.595
2014 Langlois R, Pallesen J, Ash JT, Nam Ho D, Rubinstein JL, Frank J. Automated particle picking for low-contrast macromolecules in cryo-electron microscopy. Journal of Structural Biology. 186: 1-7. PMID 24607413 DOI: 10.1016/J.Jsb.2014.03.001  0.338
2014 Boël G, Smith PC, Ning W, Englander MT, Chen B, Hashem Y, Testa AJ, Fischer JJ, Wieden HJ, Frank J, Gonzalez RL, Hunt JF. The ABC-F protein EttA gates ribosome entry into the translation elongation cycle. Nature Structural & Molecular Biology. 21: 143-51. PMID 24389466 DOI: 10.1038/Nsmb.2740  0.311
2014 Chen B, Boël G, Hashem Y, Ning W, Fei J, Wang C, Gonzalez RL, Hunt JF, Frank J. EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics. Nature Structural & Molecular Biology. 21: 152-9. PMID 24389465 DOI: 10.1038/Nsmb.2741  0.354
2014 des Georges A, Hashem Y, Unbehaun A, Grassucci RA, Taylor D, Hellen CU, Pestova TV, Frank J. Structure of the mammalian ribosomal pre-termination complex associated with eRF1.eRF3.GDPNP. Nucleic Acids Research. 42: 3409-18. PMID 24335085 DOI: 10.1093/Nar/Gkt1279  0.811
2014 Jobe A, Ruehle MD, Kieft JS, Frank J. A CRYO-EM Structure of a Minimal Translation Initiation System: Deletion in Self-Sufficient IRES Prevents Translocation Biophysical Journal. 106: 601a. DOI: 10.1016/J.Bpj.2013.11.3326  0.384
2014 Chen B, Sun M, Shen B, Lu Z, Barnard D, Lu T, Gonzalez R, Frank J. A Time-Resolved CRYO-EM Study of Ribosome Subunit Association by Mixing-Spraying Biophysical Journal. 106: 5-8. DOI: 10.1016/J.Bpj.2013.11.3310  0.343
2014 Ho DN, Shaqra A, Li W, deLivron MA, Dionne G, Gao N, Robinson VL, Frank J. The Cryo-EM Structure of the Ribosome Bound to BipA Biophysical Journal. 106: 492a. DOI: 10.1016/J.Bpj.2013.11.2752  0.387
2013 Hashem Y, des Georges A, Dhote V, Langlois R, Liao HY, Grassucci RA, Pestova TV, Hellen CU, Frank J. Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit. Nature. 503: 539-43. PMID 24185006 DOI: 10.1038/Nature12658  0.755
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Frank J, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/Ng.2711  0.353
2013 Pallesen J, Hashem Y, Korkmaz G, Koripella RK, Huang C, Ehrenberg M, Sanyal S, Frank J. Cryo-EM visualization of the ribosome in termination complex with apo-RF3 and RF1. Elife. 2: e00411. PMID 23755360 DOI: 10.7554/Elife.00411  0.383
2013 Hashem Y, des Georges A, Dhote V, Langlois R, Liao HY, Grassucci RA, Hellen CU, Pestova TV, Frank J. Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29. Cell. 153: 1108-19. PMID 23706745 DOI: 10.1016/J.Cell.2013.04.036  0.795
2013 Frank J. Story in a sample-the potential (and limitations) of cryo-electron microscopy applied to molecular machines. Biopolymers. 99: 832-6. PMID 23640776 DOI: 10.1002/Bip.22274  0.322
2013 Li W, Atkinson GC, Thakor NS, Allas U, Lu CC, Chan KY, Tenson T, Schulten K, Wilson KS, Hauryliuk V, Frank J. Mechanism of tetracycline resistance by ribosomal protection protein Tet(O). Nature Communications. 4: 1477. PMID 23403578 DOI: 10.1038/Ncomms2470  0.456
2013 Hashem Y, des Georges A, Fu J, Buss SN, Jossinet F, Jobe A, Zhang Q, Liao HY, Grassucci RA, Bajaj C, Westhof E, Madison-Antenucci S, Frank J. High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome. Nature. 494: 385-9. PMID 23395961 DOI: 10.1038/Nature11872  0.792
2013 Sharma G, Pallesen J, Das S, Grassucci R, Langlois R, Hampton CM, Kelly DF, des Georges A, Frank J. Affinity grid-based cryo-EM of PKC binding to RACK1 on the ribosome. Journal of Structural Biology. 181: 190-4. PMID 23228487 DOI: 10.1016/J.Jsb.2012.11.006  0.762
2013 Jobe A, Hashem Y, Georges Ad, Fu J, Buss SN, Jossinet F, Zhang Q, Liao HY, Grassucci B, Bajaj C, Madison-Antenucci S, Westhof E, Frank J. 33 High-resolution cryo-EM structure of theTrypanosoma brucei80S: a unique eukaryotic ribosome Journal of Biomolecular Structure and Dynamics. 31: 20-20. DOI: 10.1080/07391102.2013.786465  0.368
2012 Taylor D, Unbehaun A, Li W, Das S, Lei J, Liao HY, Grassucci RA, Pestova TV, Frank J. Cryo-EM structure of the mammalian eukaryotic release factor eRF1-eRF3-associated termination complex. Proceedings of the National Academy of Sciences of the United States of America. 109: 18413-8. PMID 23091004 DOI: 10.1073/Pnas.1216730109  0.57
2012 Frank J. Intermediate states during mRNA-tRNA translocation. Current Opinion in Structural Biology. 22: 778-85. PMID 22906732 DOI: 10.1016/J.Sbi.2012.08.001  0.347
2012 Bussiere C, Hashem Y, Arora S, Frank J, Johnson AW. Integrity of the P-site is probed during maturation of the 60S ribosomal subunit Journal of Cell Biology. 197: 747-759. PMID 22689654 DOI: 10.1083/Jcb.201112131  0.316
2012 Agirrezabala X, Liao HY, Schreiner E, Fu J, Ortiz-Meoz RF, Schulten K, Green R, Frank J. Structural characterization of mRNA-tRNA translocation intermediates. Proceedings of the National Academy of Sciences of the United States of America. 109: 6094-9. PMID 22467828 DOI: 10.1073/Pnas.1201288109  0.525
2012 Henderson R, Sali A, Baker ML, Carragher B, Devkota B, Downing KH, Egelman EH, Feng Z, Frank J, Grigorieff N, Jiang W, Ludtke SJ, Medalia O, Penczek PA, Rosenthal PB, et al. Outcome of the first electron microscopy validation task force meeting. Structure (London, England : 1993). 20: 205-14. PMID 22325770 DOI: 10.1016/J.Str.2011.12.014  0.634
2012 Leith A, Baxter W, Frank J. Use of SPIDER and SPIRE in image reconstruction International Tables For Crystallography. DOI: 10.1107/97809553602060000874  0.323
2012 Ho DN, deLivron MA, Gao N, Robinson VL, Frank J. Toward a Cryo-Em Structure of the Ribosome Bound to BipA Biophysical Journal. 102: 69. DOI: 10.1016/J.Bpj.2011.11.406  0.381
2012 Sharma G, Stupina V, Pallesen J, Shapiro B, Simon A, Dinman J, Frank J. Cryo-Electron Microscopy (Cryo-EM) Structure of a Cap-Independent Translational Enhancer of the Turnip Crinkle Virus (TCV) Bound to the Eukaryotic Ribosome Biophysical Journal. 102: 393a. DOI: 10.1016/J.Bpj.2011.11.2147  0.652
2011 Fu J, Hashem Y, Wower J, Frank J. tmRNA on its way through the ribosome: two steps of resume, and what next? Rna Biology. 8: 586-90. PMID 21593606 DOI: 10.4161/Rna.8.4.15585  0.385
2011 Fu J, Munro JB, Blanchard SC, Frank J. Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation. Proceedings of the National Academy of Sciences of the United States of America. 108: 4817-21. PMID 21383139 DOI: 10.1073/Pnas.1101503108  0.376
2011 Agirrezabala X, Schreiner E, Trabuco LG, Lei J, Ortiz-Meoz RF, Schulten K, Green R, Frank J. Structural insights into cognate versus near-cognate discrimination during decoding. The Embo Journal. 30: 1497-507. PMID 21378755 DOI: 10.1038/Emboj.2011.58  0.569
2011 Li W, Trabuco LG, Schulten K, Frank J. Molecular dynamics of EF-G during translocation. Proteins. 79: 1478-86. PMID 21365677 DOI: 10.1002/Prot.22976  0.501
2011 Harrison OJ, Jin X, Hong S, Bahna F, Ahlsen G, Brasch J, Wu Y, Vendome J, Felsovalyi K, Hampton CM, Troyanovsky RB, Ben-Shaul A, Frank J, Troyanovsky SM, Shapiro L, et al. The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. Structure (London, England : 1993). 19: 244-56. PMID 21300292 DOI: 10.1016/J.Str.2010.11.016  0.302
2011 Huang T, Shaikh TR, Gupta K, Contreras-Martin LM, Grassucci RA, Van Duyne GD, Frank J, Belfort M. The group II intron ribonucleoprotein precursor is a large, loosely packed structure Nucleic Acids Research. 39: 2845-2854. PMID 21131279 DOI: 10.1093/Nar/Gkq1202  0.363
2011 Liao HY, Langlois R, Frank J. Classification of Projections in Single Particle Electron Microscopy using Common Line Similarity Measure Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3538  0.318
2011 Hashem Y, Fu J, Frank J. The First Atomic Model of the Transfer-Messenger RNA in the Resume State Biophysical Journal. 100: 4-5. DOI: 10.1016/J.Bpj.2010.12.2402  0.393
2010 Frank J. The Ribosome Comes Alive. Israel Journal of Chemistry. 50: 95-98. PMID 21072331 DOI: 10.1002/Ijch.201000010  0.383
2010 Fu J, Hashem Y, Wower I, Lei J, Liao HY, Zwieb C, Wower J, Frank J. Visualizing the transfer-messenger RNA as the ribosome resumes translation. The Embo Journal. 29: 3819-25. PMID 20940705 DOI: 10.1038/Emboj.2010.255  0.413
2010 Sengupta J, Bussiere C, Pallesen J, West M, Johnson AW, Frank J. Characterization of the nuclear export adaptor protein Nmd3 in association with the 60S ribosomal subunit. The Journal of Cell Biology. 189: 1079-86. PMID 20584915 DOI: 10.1083/Jcb.201001124  0.416
2010 Agirrezabala X, Frank J. From DNA to proteins via the ribosome: structural insights into the workings of the translation machinery. Human Genomics. 4: 226-37. PMID 20511136 DOI: 10.1186/1479-7364-4-4-226  0.34
2010 Frank J, Gonzalez RL. Structure and dynamics of a processive Brownian motor: the translating ribosome. Annual Review of Biochemistry. 79: 381-412. PMID 20235828 DOI: 10.1146/Annurev-Biochem-060408-173330  0.374
2010 Réblová K, Rázga F, Li W, Gao H, Frank J, Sponer J. Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM. Nucleic Acids Research. 38: 1325-40. PMID 19952067 DOI: 10.1093/Nar/Gkp1057  0.308
2010 Liao HY, Frank J. On Bootstrap Techniques For Classifying Projections in Single Particle Electron Microscopy Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.066  0.315
2009 Agirrezabala X, Frank J. Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu. Quarterly Reviews of Biophysics. 42: 159-200. PMID 20025795 DOI: 10.1017/S0033583509990060  0.376
2009 Frank J. Single-particle reconstruction of biological macromolecules in electron microscopy--30 years. Quarterly Reviews of Biophysics. 42: 139-58. PMID 20025794 DOI: 10.1017/S0033583509990059  0.332
2009 Taylor DJ, Devkota B, Huang AD, Topf M, Narayanan E, Sali A, Harvey SC, Frank J. Comprehensive molecular structure of the eukaryotic ribosome. Structure (London, England : 1993). 17: 1591-604. PMID 20004163 DOI: 10.1016/J.Str.2009.09.015  0.567
2009 Shi Y, Di Giammartino DC, Taylor D, Sarkeshik A, Rice WJ, Yates JR, Frank J, Manley JL. Molecular architecture of the human pre-mRNA 3' processing complex. Molecular Cell. 33: 365-76. PMID 19217410 DOI: 10.1016/J.Molcel.2008.12.028  0.545
2009 Villa E, Sengupta J, Trabuco LG, LeBarron J, Baxter WT, Shaikh TR, Grassucci RA, Nissen P, Ehrenberg M, Schulten K, Frank J. Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 106: 1063-8. PMID 19122150 DOI: 10.1073/Pnas.0811370106  0.665
2009 Renken C, Hsieh CE, Marko M, Rath B, Leith A, Wagenknecht T, Frank J, Mannella CA. Structure of frozen-hydrated triad junctions: a case study in motif searching inside tomograms. Journal of Structural Biology. 165: 53-63. PMID 19028586 DOI: 10.1016/J.Jsb.2008.09.011  0.588
2009 Fu J, Lei J, Wower I, Wower J, Frank J. Visualizing tmRNA after its accommodation in the Ribosome Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.946  0.316
2009 Gao H, Frank J. Analysis Of Ribosomal Dynamics As Revealed By Cryo-EM And Flexible Fitting Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.3037  0.395
2008 Shaikh TR, Gao H, Baxter WT, Asturias FJ, Boisset N, Leith A, Frank J. SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs. Nature Protocols. 3: 1941-74. PMID 19180078 DOI: 10.1038/Nprot.2008.156  0.662
2008 Li W, Agirrezabala X, Lei J, Bouakaz L, Brunelle JL, Ortiz-Meoz RF, Green R, Sanyal S, Ehrenberg M, Frank J. Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. The Embo Journal. 27: 3322-31. PMID 19020518 DOI: 10.1038/Emboj.2008.243  0.361
2008 Agirrezabala X, Lei J, Brunelle JL, Ortiz-Meoz RF, Green R, Frank J. Visualization of the hybrid state of tRNA binding promoted by spontaneous ratcheting of the ribosome. Molecular Cell. 32: 190-7. PMID 18951087 DOI: 10.1016/J.Molcel.2008.10.001  0.346
2008 Sengupta J, Nilsson J, Gursky R, Kjeldgaard M, Nissen P, Frank J. Visualization of the eEF2-80S ribosome transition-state complex by cryo-electron microscopy. Journal of Molecular Biology. 382: 179-87. PMID 18644383 DOI: 10.1016/J.Jmb.2008.07.004  0.414
2008 LeBarron J, Grassucci RA, Shaikh TR, Baxter WT, Sengupta J, Frank J. Exploration of parameters in cryo-EM leading to an improved density map of the E. coli ribosome. Journal of Structural Biology. 164: 24-32. PMID 18606549 DOI: 10.1016/J.Jsb.2008.05.007  0.309
2008 Trabuco LG, Villa E, Mitra K, Frank J, Schulten K. Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics. Structure (London, England : 1993). 16: 673-83. PMID 18462672 DOI: 10.1016/J.Str.2008.03.005  0.666
2008 Grassucci RA, Taylor D, Frank J. Visualization of macromolecular complexes using cryo-electron microscopy with FEI Tecnai transmission electron microscopes. Nature Protocols. 3: 330-9. PMID 18274535 DOI: 10.1038/Nprot.2007.474  0.541
2008 Villa E, Trabuco L, Mitra K, Sengupta J, Frank J, Schulten K. Merging data from cryo-EM and X-ray crystallography to reveal biomolecular function Acta Crystallographica Section a Foundations of Crystallography. 64: C47-C47. DOI: 10.1107/S0108767308098498  0.591
2008 Marko M, Hsieh C, Salmon N, Rodriguez M, Frank J, Mannella C. FIB milling of frozen-hydrated cells and tissue for TEM cryo-tomography Microscopy and Microanalysis. 14: 968-969. DOI: 10.1017/S1431927608088673  0.521
2007 Grassucci RA, Taylor DJ, Frank J. Preparation of macromolecular complexes for cryo-electron microscopy. Nature Protocols. 2: 3239-46. PMID 18079724 DOI: 10.1038/Nprot.2007.452  0.528
2007 Frank J, Gao H, Sengupta J, Gao N, Taylor DJ. The process of mRNA-tRNA translocation. Proceedings of the National Academy of Sciences of the United States of America. 104: 19671-8. PMID 18003906 DOI: 10.1073/Pnas.0708517104  0.539
2007 Gao N, Zavialov AV, Ehrenberg M, Frank J. Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits. Journal of Molecular Biology. 374: 1345-58. PMID 17996252 DOI: 10.1016/J.Jmb.2007.10.021  0.371
2007 Li W, Frank J. Transfer RNA in the hybrid P/E state: correlating molecular dynamics simulations with cryo-EM data. Proceedings of the National Academy of Sciences of the United States of America. 104: 16540-5. PMID 17925437 DOI: 10.1073/Pnas.0708094104  0.346
2007 Gao H, Zhou Z, Rawat U, Huang C, Bouakaz L, Wang C, Cheng Z, Liu Y, Zavialov A, Gursky R, Sanyal S, Ehrenberg M, Frank J, Song H. RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors. Cell. 129: 929-41. PMID 17540173 DOI: 10.1016/J.Cell.2007.03.050  0.354
2007 Taylor DJ, Nilsson J, Merrill AR, Andersen GR, Nissen P, Frank J. Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation. The Embo Journal. 26: 2421-31. PMID 17446867 DOI: 10.1038/Sj.Emboj.7601677  0.586
2007 Nilsson J, Sengupta J, Gursky R, Nissen P, Frank J. Comparison of fungal 80 S ribosomes by cryo-EM reveals diversity in structure and conformation of rRNA expansion segments. Journal of Molecular Biology. 369: 429-38. PMID 17434183 DOI: 10.1016/J.Jmb.2007.03.035  0.38
2007 Marko M, Hsieh C, Schalek R, Frank J, Mannella C. Focused-ion-beam thinning of frozen-hydrated biological specimens for cryo-electron microscopy. Nature Methods. 4: 215-7. PMID 17277781 DOI: 10.1038/Nmeth1014  0.585
2007 Allen GS, Frank J. Structural insights on the translation initiation complex: ghosts of a universal initiation complex. Molecular Microbiology. 63: 941-50. PMID 17238926 DOI: 10.1111/J.1365-2958.2006.05574.X  0.382
2007 Scheres SH, Gao H, Valle M, Herman GT, Eggermont PP, Frank J, Carazo JM. Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization. Nature Methods. 4: 27-9. PMID 17179934 DOI: 10.1038/Nmeth992  0.794
2007 Gillet R, Kaur S, Li W, Hallier M, Felden B, Frank J. Scaffolding as an organizing principle in trans-translation. The roles of small protein B and ribosomal protein S1. The Journal of Biological Chemistry. 282: 6356-63. PMID 17179154 DOI: 10.1074/Jbc.M609658200  0.367
2007 LeBarron J, Mitra K, Frank J. Displaying 3D data on RNA secondary structures: coloRNA. Journal of Structural Biology. 157: 262-70. PMID 17070699 DOI: 10.1016/J.Jsb.2006.08.018  0.354
2007 Fu J, Gao H, Frank J. Unsupervised classification of single particles by cluster tracking in multi-dimensional space. Journal of Structural Biology. 157: 226-39. PMID 16931050 DOI: 10.1016/J.Jsb.2006.06.012  0.311
2007 Yang C, Penczek PA, Leith A, Asturias FJ, Ng EG, Glaeser RM, Frank J. The parallelization of SPIDER on distributed-memory computers using MPI Journal of Structural Biology. 157: 240-249. PMID 16859923 DOI: 10.1016/J.Jsb.2006.05.011  0.495
2007 Taylor DJ, Frank J, Kinzy TG. 3 Structure and Function of the Eukaryotic Ribosome and Elongation Factors Cold Spring Harbor Monograph Archive. 48: 59-85. DOI: 10.1101/087969767.48.59  0.405
2007 Marko M, Scheeff M, Salmon N, Hsieh C, Rodriguez M, Frank J, Mannella C. Use of Focused Ion Beam Milling for Preparation of Frozen-Hydrated Specimens for TEM Tomography Microscopy and Microanalysis. 13: 1460-1461. DOI: 10.1017/S1431927607076520  0.519
2006 Mitra K, Frank J, Driessen A. Co- and post-translational translocation through the protein-conducting channel: analogous mechanisms at work? Nature Structural & Molecular Biology. 13: 957-64. PMID 17082791 DOI: 10.1038/Nsmb1166  0.328
2006 Kaur S, Gillet R, Li W, Gursky R, Frank J. Cryo-EM visualization of transfer messenger RNA with two SmpBs in a stalled ribosome. Proceedings of the National Academy of Sciences of the United States of America. 103: 16484-9. PMID 17056712 DOI: 10.1073/Pnas.0607438103  0.395
2006 Berman HM, Burley SK, Chiu W, Sali A, Adzhubei A, Bourne PE, Bryant SH, Dunbrack RL, Fidelis K, Frank J, Godzik A, Henrick K, Joachimiak A, Heymann B, Jones D, et al. Outcome of a Workshop on Archiving Structural Models of Biological Macromolecules Structure. 14: 1211-1217. PMID 16955948 DOI: 10.1016/J.Str.2006.06.005  0.425
2006 Slagter-Jäger JG, Allen GS, Smith D, Hahn IA, Frank J, Belfort M. Visualization of a group II intron in the 23S rRNA of a stable ribosome. Proceedings of the National Academy of Sciences of the United States of America. 103: 9838-43. PMID 16785426 DOI: 10.1073/Pnas.0603956103  0.38
2006 Marko M, Hsieh C, Moberlychan W, Mannella CA, Frank J. Focused ion beam milling of vitreous water: prospects for an alternative to cryo-ultramicrotomy of frozen-hydrated biological samples. Journal of Microscopy. 222: 42-7. PMID 16734713 DOI: 10.1111/J.1365-2818.2006.01567.X  0.553
2006 Mitra K, Frank J. A model for co-translational translocation: ribosome-regulated nascent polypeptide translocation at the protein-conducting channel. Febs Letters. 580: 3353-60. PMID 16714018 DOI: 10.1016/J.Febslet.2006.05.019  0.343
2006 Mitra K, Schaffitzel C, Fabiola F, Chapman MS, Ban N, Frank J. Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements. Molecular Cell. 22: 533-43. PMID 16713583 DOI: 10.1016/J.Molcel.2006.05.003  0.372
2006 Mitra K, Frank J. Ribosome dynamics: insights from atomic structure modeling into cryo-electron microscopy maps. Annual Review of Biophysics and Biomolecular Structure. 35: 299-317. PMID 16689638 DOI: 10.1146/Annurev.Biophys.35.040405.101950  0.407
2006 Li W, Sengupta J, Rath BK, Frank J. Functional conformations of the L11-ribosomal RNA complex revealed by correlative analysis of cryo-EM and molecular dynamics simulations. Rna (New York, N.Y.). 12: 1240-53. PMID 16682558 DOI: 10.1261/Rna.2294806  0.397
2006 Gao N, Frank J. A library of RNA bridges. Nature Chemical Biology. 2: 231-2. PMID 16619019 DOI: 10.1038/Nchembio0506-231  0.349
2006 Penczek PA, Frank J, Spahn CM. A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation. Journal of Structural Biology. 154: 184-94. PMID 16520062 DOI: 10.1016/J.Jsb.2005.12.013  0.661
2006 Penczek PA, Yang C, Frank J, Spahn CM. Estimation of variance in single-particle reconstruction using the bootstrap technique. Journal of Structural Biology. 154: 168-83. PMID 16510296 DOI: 10.1016/J.Jsb.2006.01.003  0.645
2006 Rawat U, Gao H, Zavialov A, Gursky R, Ehrenberg M, Frank J. Interactions of the release factor RF1 with the ribosome as revealed by cryo-EM. Journal of Molecular Biology. 357: 1144-53. PMID 16476444 DOI: 10.1016/J.Jmb.2006.01.038  0.396
2006 Hsieh CE, Leith A, Mannella CA, Frank J, Marko M. Towards high-resolution three-dimensional imaging of native mammalian tissue: electron tomography of frozen-hydrated rat liver sections. Journal of Structural Biology. 153: 1-13. PMID 16343943 DOI: 10.1016/J.Jsb.2005.10.004  0.586
2006 Frank J, Spahn CMT. The ribosome and the mechanism of protein synthesis Reports On Progress in Physics. 69: 1383-1417. DOI: 10.1088/0034-4885/69/5/R03  0.377
2006 Mitra K, Schaffitzel C, Shaikh T, Tama F, Jenni S, Brooks CL, Ban N, Frank J. Erratum: Structure of the E. coli protein-conducting channel bound to a translating ribosome Nature. 443: 718-718. DOI: 10.1038/Nature05086  0.322
2006 Penczek PA, Frank J. Determination of Resolution in Electron Tomography Microscopy and Microanalysis. 12: 1542-1543. DOI: 10.1017/S143192760606853X  0.304
2006 Penczek PA, Frank J, Spahn CMT. Conformational Heterogeneity of Macromolecules Analyzed by Cryo-Electron Microscopy Microscopy and Microanalysis. 12: 386-387. DOI: 10.1017/S1431927606068528  0.33
2006 Marko M, Hsieh CE, Shalek R, Ting CS, Mannella CA, Frank J. Focused ion beam (FIB) preparation methods for 3-D biological cryo-TEM Microscopy and Microanalysis. 12: 98-99. DOI: 10.1017/S1431927606066621  0.529
2005 Datta PP, Sharma MR, Qi L, Frank J, Agrawal RK. Interaction of the G' domain of elongation factor G and the C-terminal domain of ribosomal protein L7/L12 during translocation as revealed by cryo-EM. Molecular Cell. 20: 723-31. PMID 16337596 DOI: 10.1016/J.Molcel.2005.10.028  0.318
2005 Adiga U, Baxter WT, Hall RJ, Rockel B, Rath BK, Frank J, Glaeser R. Particle picking by segmentation: a comparative study with SPIDER-based manual particle picking. Journal of Structural Biology. 152: 211-20. PMID 16330229 DOI: 10.1016/J.Jsb.2005.09.007  0.54
2005 Mitra K, Schaffitzel C, Shaikh T, Tama F, Jenni S, Brooks CL, Ban N, Frank J. Structure of the E. coli protein-conducting channel bound to a translating ribosome. Nature. 438: 318-24. PMID 16292303 DOI: 10.1038/Nature04133  0.408
2005 Gao H, Ayub MJ, Levin MJ, Frank J. The structure of the 80S ribosome from Trypanosoma cruzi reveals unique rRNA components. Proceedings of the National Academy of Sciences of the United States of America. 102: 10206-11. PMID 16014419 DOI: 10.1073/Pnas.0500926102  0.42
2005 Gao N, Zavialov AV, Li W, Sengupta J, Valle M, Gursky RP, Ehrenberg M, Frank J. Mechanism for the disassembly of the posttermination complex inferred from cryo-EM studies. Molecular Cell. 18: 663-74. PMID 15949441 DOI: 10.1016/J.Molcel.2005.05.005  0.782
2005 Allen GS, Zavialov A, Gursky R, Ehrenberg M, Frank J. The cryo-EM structure of a translation initiation complex from Escherichia coli. Cell. 121: 703-12. PMID 15935757 DOI: 10.1016/J.Cell.2005.03.023  0.389
2005 Halic M, Becker T, Frank J, Spahn CM, Beckmann R. Localization and dynamic behavior of ribosomal protein L30e. Nature Structural & Molecular Biology. 12: 467-8. PMID 15864315 DOI: 10.1038/Nsmb933  0.65
2005 Gao H, Frank J. Molding atomic structures into intermediate-resolution cryo-EM density maps of ribosomal complexes using real-space refinement. Structure (London, England : 1993). 13: 401-6. PMID 15766541 DOI: 10.1016/J.Str.2005.01.004  0.331
2005 Frank J, Sengupta J, Gao H, Li W, Valle M, Zavialov A, Ehrenberg M. The role of tRNA as a molecular spring in decoding, accommodation, and peptidyl transfer. Febs Letters. 579: 959-62. PMID 15680982 DOI: 10.1016/J.Febslet.2004.10.105  0.778
2005 Frank J, Gao H, Li W, Sengupta J. Cryo-electron Microscopy of the Ribosome: Methods of Fitting, and Inference of Dynamics Acta Crystallographica Section A. 61: 67-67. DOI: 10.1107/S010876730509714X  0.328
2005 Marko M, Hsieh C, Dunn K, Typke D, Mannella C, Frank J. Use of the Zernike Phase Plate for Electron Tomography of Frozen-Hydrated Specimens Microscopy and Microanalysis. 11: 310-311. DOI: 10.1017/S1431927605501557  0.546
2005 Marko M, Hsieh C, MoberlyChan WJ, Mannella CA, Frank J. Feasibility of Focused Ion Beam Milling for Preparation of TEM Specimens of Biological Material Embedded in Vitreous Ice Microscopy and Microanalysis. 11: 802-803. DOI: 10.1017/S1431927605500709  0.52
2004 Nilsson J, Sengupta J, Frank J, Nissen P. Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome. Embo Reports. 5: 1137-41. PMID 15577927 DOI: 10.1038/Sj.Embor.7400291  0.351
2004 Gao H, Valle M, Ehrenberg M, Frank J. Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset. Journal of Structural Biology. 147: 283-90. PMID 15450297 DOI: 10.1016/J.Jsb.2004.02.008  0.782
2004 Bzowska A, Koellner G, Wielgus-Kutrowska B, Stroh A, Raszewski G, Holý A, Steiner T, Frank J. Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis. Journal of Molecular Biology. 342: 1015-32. PMID 15342253 DOI: 10.1016/J.Jmb.2004.07.017  0.323
2004 Sengupta J, Nilsson J, Gursky R, Spahn CM, Nissen P, Frank J. Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM. Nature Structural & Molecular Biology. 11: 957-62. PMID 15334071 DOI: 10.1038/Nsmb822  0.645
2004 Spahn CM, Jan E, Mulder A, Grassucci RA, Sarnow P, Frank J. Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor. Cell. 118: 465-75. PMID 15315759 DOI: 10.1016/J.Cell.2004.08.001  0.671
2004 Agrawal RK, Sharma MR, Kiel MC, Hirokawa G, Booth TM, Spahn CM, Grassucci RA, Kaji A, Frank J. Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: functional implications. Proceedings of the National Academy of Sciences of the United States of America. 101: 8900-5. PMID 15178758 DOI: 10.1073/Pnas.0401904101  0.685
2004 Rath BK, Frank J. Fast automatic particle picking from cryo-electron micrographs using a locally normalized cross-correlation function: a case study Journal of Structural Biology. 145: 84-90. PMID 15065676 DOI: 10.1016/J.Jsb.2003.11.015  0.324
2004 Halic M, Becker T, Pool MR, Spahn CM, Grassucci RA, Frank J, Beckmann R. Structure of the signal recognition particle interacting with the elongation-arrested ribosome. Nature. 427: 808-14. PMID 14985753 DOI: 10.1038/Nature02342  0.673
2004 Spahn CM, Gomez-Lorenzo MG, Grassucci RA, Jørgensen R, Andersen GR, Beckmann R, Penczek PA, Ballesta JP, Frank J. Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. The Embo Journal. 23: 1008-19. PMID 14976550 DOI: 10.1038/Sj.Emboj.7600102  0.688
2004 Gao H, Valle M, Ehrenberg M, Frank J. Corrigendum to “Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset” [J. Struct. Biol. 147 (2004) 283–290] Journal of Structural Biology. 148: 375. DOI: 10.1016/J.Jsb.2004.09.002  0.744
2003 Frank J. Toward an understanding of the structural basis of translation. Genome Biology. 4: 237-237. PMID 14659007 DOI: 10.1186/Gb-2003-4-12-237  0.374
2003 Rath BK, Hegerl R, Leith A, Shaikh TR, Wagenknecht T, Frank J. Fast 3D motif search of EM density maps using a locally normalized cross-correlation function. Journal of Structural Biology. 144: 95-103. PMID 14643212 DOI: 10.1016/J.Jsb.2003.09.029  0.368
2003 Gomez-Lorenzo MG, Valle M, Frank J, Gruss C, Sorzano CO, Chen XS, Donate LE, Carazo JM. Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication. The Embo Journal. 22: 6205-13. PMID 14633980 DOI: 10.1093/Emboj/Cdg612  0.766
2003 Valle M, Zavialov A, Li W, Stagg SM, Sengupta J, Nielsen RC, Nissen P, Harvey SC, Ehrenberg M, Frank J. Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy. Nature Structural Biology. 10: 899-906. PMID 14566331 DOI: 10.1038/Nsb1003  0.793
2003 Moccia R, Chen D, Lyles V, Kapuya E, E Y, Kalachikov S, Spahn CM, Frank J, Kandel ER, Barad M, Martin KC. An unbiased cDNA library prepared from isolated Aplysia sensory neuron processes is enriched for cytoskeletal and translational mRNAs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9409-17. PMID 14561869 DOI: 10.1523/Jneurosci.23-28-09409.2003  0.618
2003 Tama F, Valle M, Frank J, Brooks CL. Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 100: 9319-23. PMID 12878726 DOI: 10.1073/Pnas.1632476100  0.788
2003 Valle M, Zavialov A, Sengupta J, Rawat U, Ehrenberg M, Frank J. Locking and unlocking of ribosomal motions. Cell. 114: 123-34. PMID 12859903 DOI: 10.1016/S0092-8674(03)00476-8  0.769
2003 Gao H, Sengupta J, Valle M, Korostelev A, Eswar N, Stagg SM, Van Roey P, Agrawal RK, Harvey SC, Sali A, Chapman MS, Frank J. Study of the structural dynamics of the E coli 70S ribosome using real-space refinement. Cell. 113: 789-801. PMID 12809609 DOI: 10.1016/S0092-8674(03)00427-6  0.782
2003 Valle M, Gillet R, Kaur S, Henne A, Ramakrishnan V, Frank J. Visualizing tmRNA entry into a stalled ribosome Science. 300: 127-130. PMID 12677067 DOI: 10.1126/Science.1081798  0.778
2003 Yarus M, Valle M, Frank J. A twisted tRNA intermediate sets the threshold for decoding. Rna (New York, N.Y.). 9: 384-5. PMID 12649490 DOI: 10.1261/Rna.2184703  0.779
2003 Frank J. Electron microscopy of functional ribosome complexes Biopolymers. 68: 223-233. PMID 12548625 DOI: 10.1002/Bip.10210  0.369
2003 Rawat UB, Zavialov AV, Sengupta J, Valle M, Grassucci RA, Linde J, Vestergaard B, Ehrenberg M, Frank J. A cryo-electron microscopic study of ribosome-bound termination factor RF2. Nature. 421: 87-90. PMID 12511960 DOI: 10.1038/Nature01224  0.772
2003 Hsieh C-, Marko M, Leith A, Frank J, Mannella CA. Electron Tomographic Comparison of Frozen-Hydrated and Freeze-Substituted Sections of High-Pressure Frozen Rat-Liver Tissue Microscopy and Microanalysis. 9: 1178-1179. DOI: 10.1017/S1431927603445893  0.536
2002 Gao H, Spahn CM, Grassucci RA, Frank J. An assay for local quality in cryo-electron micrographs of single particles. Ultramicroscopy. 93: 169-78. PMID 12425594 DOI: 10.1016/S0304-3991(02)00157-2  0.641
2002 Stagg SM, Valle M, Agrawal RK, Frank J, Harvey SC. Problems with the transorientation hypothesis. Rna (New York, N.Y.). 8: 1093-4. PMID 12358427 DOI: 10.1017/S1355838202027061  0.782
2002 Frank J, Wagenknecht T, McEwen BF, Marko M, Hsieh CE, Mannella CA. Three-dimensional imaging of biological complexity. Journal of Structural Biology. 138: 85-91. PMID 12160704 DOI: 10.1016/S1047-8477(02)00019-9  0.612
2002 Hsieh CE, Marko M, Frank J, Mannella CA. Electron tomographic analysis of frozen-hydrated tissue sections. Journal of Structural Biology. 138: 63-73. PMID 12160702 DOI: 10.1016/S1047-8477(02)00034-5  0.583
2002 Valle M, Sengupta J, Swami NK, Grassucci RA, Burkhardt N, Nierhaus KH, Agrawal RK, Frank J. Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process. The Embo Journal. 21: 3557-67. PMID 12093756 DOI: 10.1093/Emboj/Cdf326  0.795
2002 Frank J. Single-particle imaging of macromolecules by cryo-electron microscopy Annual Review of Biophysics and Biomolecular Structure. 31: 303-319. PMID 11988472 DOI: 10.1146/Annurev.Biophys.31.082901.134202  0.387
2002 Hsieh CE, Marko M, Frank J, Mannella CA. Electron Tomography of Frozen-Hydrated Sections Microscopy and Microanalysis. 8: 878-879. DOI: 10.1017/S1431927602106726  0.556
2002 Frank J, Sengupta J, Valle M, Agrawal R. The Ribosome – Ligand Interactions and Dynamics as Inferred by Cryo-EM Microscopy and Microanalysis. 8: 206-207. DOI: 10.1017/S1431927602100031  0.746
2001 Beckmann R, Spahn CM, Frank J, Blobel G. The active 80S ribosome-Sec61 complex. Cold Spring Harbor Symposia On Quantitative Biology. 66: 543-54. PMID 12762056 DOI: 10.1101/Sqb.2001.66.543  0.624
2001 Frank J. Ribosomal dynamics explored by cryo-electron microscopy Methods. 25: 309-315. PMID 11860285 DOI: 10.1006/Meth.2001.1243  0.371
2001 Spahn CM, Beckmann R, Eswar N, Penczek PA, Sali A, Blobel G, Frank J. Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions. Cell. 107: 373-86. PMID 11701127 DOI: 10.1016/S0092-8674(01)00539-6  0.687
2001 Beckmann R, Spahn CM, Eswar N, Helmers J, Penczek PA, Sali A, Frank J, Blobel G. Architecture of the protein-conducting channel associated with the translating 80S ribosome. Cell. 107: 361-72. PMID 11701126 DOI: 10.1016/S0092-8674(01)00541-4  0.676
2001 McEwen BF, Frank J. Electron tomographic and other approaches for imaging molecular machines. Current Opinion in Neurobiology. 11: 594-600. PMID 11595494 DOI: 10.1016/S0959-4388(00)00255-5  0.318
2001 Sengupta J, Agrawal RK, Frank J. Visualization of protein S1 within the 30S ribosomal subunit and its interaction with messenger RNA. Proceedings of the National Academy of Sciences of the United States of America. 98: 11991-11996. PMID 11593008 DOI: 10.1073/Pnas.211266898  0.384
2001 Agrawal RK, Linde J, Sengupta J, Nierhaus KH, Frank J. Localization of L11 Protein on the Ribosome and Elucidation of its Involvement in EF-G-dependent Translocation Journal of Molecular Biology. 311: 777-787. PMID 11518530 DOI: 10.1006/Jmbi.2001.4907  0.342
2001 Gabashvili IS, Gregory ST, Valle M, Grassucci R, Worbs M, Wahl MC, Dahlberg AE, Frank J. The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. Molecular Cell. 8: 181-8. PMID 11511371 DOI: 10.1016/S1097-2765(01)00293-3  0.785
2001 Frank J. Cryo-electron microscopy as an investigative tool: The ribosome as an example Bioessays. 23: 725-732. PMID 11494321 DOI: 10.1002/Bies.1102  0.438
2001 Spahn CM, Blaha G, Agrawal RK, Penczek P, Grassucci RA, Trieber CA, Connell SR, Taylor DE, Nierhaus KH, Frank J. Localization of the ribosomal protection protein Tet(O) on the ribosome and the mechanism of tetracycline resistance. Molecular Cell. 7: 1037-45. PMID 11389850 DOI: 10.1016/S1097-2765(01)00238-6  0.649
2001 Spahn CM, Kieft JS, Grassucci RA, Penczek PA, Zhou K, Doudna JA, Frank J. Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit. Science (New York, N.Y.). 291: 1959-62. PMID 11239155 DOI: 10.1126/Science.1058409  0.663
2001 McEwen BF, Barnard RM, Hsieh C, Frank J. Using Electron Tomography to Determine How Kinetochores Bind and Alter the Conformations of Microtubule Plus Ends Microscopy and Microanalysis. 7: 86-87. DOI: 10.1017/S1431927600026507  0.326
2000 VanLoock MS, Agrawal RK, Gabashvili IS, Qi L, Frank J, Harvey SC. Movement of the decoding region of the 16 S ribosomal RNA accompanies tRNA translocation. Journal of Molecular Biology. 304: 507-15. PMID 11099376 DOI: 10.1006/Jmbi.2000.4213  0.758
2000 Spahn CM, Penczek PA, Leith A, Frank J. A method for differentiating proteins from nucleic acids in intermediate-resolution density maps: cryo-electron microscopy defines the quaternary structure of the Escherichia coli 70S ribosome. Structure (London, England : 1993). 8: 937-48. PMID 10986461 DOI: 10.1016/S0969-2126(00)00185-4  0.661
2000 Wriggers W, Agrawal RK, Drew DL, McCammon A, Frank J. Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structures. Biophysical Journal. 79: 1670-8. PMID 10969026 DOI: 10.1016/S0006-3495(00)76416-2  0.377
2000 Agrawal RK, Spahn CM, Penczek P, Grassucci RA, Nierhaus KH, Frank J. Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. The Journal of Cell Biology. 150: 447-60. PMID 10931859 DOI: 10.1083/Jcb.150.3.447  0.644
2000 Frank J, Agrawal RK. A ratchet-like inter-subunit reorganization of the ribosome during translocation. Nature. 406: 318-322. PMID 10917535 DOI: 10.1038/35018597  0.394
2000 Frank J. The ribosome – a macromolecular machine par excellence Chemistry & Biology. 7. PMID 10873840 DOI: 10.1016/S1074-5521(00)00127-7  0.403
2000 Gomez-Lorenzo MG, Spahn CM, Agrawal RK, Grassucci RA, Penczek P, Chakraburtty K, Ballesta JP, Lavandera JL, Garcia-Bustos JF, Frank J. Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 A resolution. The Embo Journal. 19: 2710-8. PMID 10835368 DOI: 10.1093/Emboj/19.11.2710  0.692
2000 Blaha G, Stelzl U, Spahn CM, Agrawal RK, Frank J, Nierhaus KH. Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy. Methods in Enzymology. 317: 292-309. PMID 10829287 DOI: 10.1016/S0076-6879(00)17021-1  0.682
2000 Gabashvili IS, Agrawal RK, Spahn CM, Grassucci RA, Svergun DI, Frank J, Penczek P. Solution structure of the E. coli 70S ribosome at 11.5 A resolution. Cell. 100: 537-49. PMID 10721991 DOI: 10.1016/S0092-8674(00)80690-X  0.808
2000 Penczek P, Spahn CMT, Agrawal RK, Gabashvili IS, Grassucci RA, Frank J. Advances in High Resolution Cryo-EM Studies: the Quartenary Structure of the 70S E.Coli Ribosome Revealed at 11.5Å Resolution. Microscopy and Microanalysis. 6: 262-263. DOI: 10.1017/S1431927600033808  0.736
1999 Spahn CM, Grassucci RA, Penczek P, Frank J. Direct three-dimensional localization and positive identification of RNA helices within the ribosome by means of genetic tagging and cryo-electron microscopy. Structure (London, England : 1993). 7: 1567-73. PMID 10647187 DOI: 10.1016/S0969-2126(00)88347-1  0.661
1999 Penczek P, Ban N, Grassucci RA, Agrawal RK, Frank J. Haloarcula marismortui 50S subunit-complementarity of electron microscopy and X-Ray crystallographic information. Journal of Structural Biology. 128: 44-50. PMID 10600557 DOI: 10.1006/Jsbi.1999.4157  0.302
1999 Frank J, Heagle AB, Agrawal RK. Animation of the dynamical events of the elongation cycle based on cryoelectron microscopy of functional complexes of the ribosome. Journal of Structural Biology. 128: 15-18. PMID 10600553 DOI: 10.1006/Jsbi.1999.4138  0.361
1999 Gabashvili IS, Agrawal RK, Grassucci R, Squires CL, Dahlberg AE, Frank J. Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA. The Embo Journal. 18: 6501-7. PMID 10562562 DOI: 10.1093/Emboj/18.22.6501  0.762
1999 Agrawal RK, Heagle AB, Penczek P, Grassucci RA, Frank J. EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome. Nature Structural & Molecular Biology. 6: 643-647. PMID 10404220 DOI: 10.1038/10695  0.325
1999 Agrawal RK, Frank J. Structural studies of the translational apparatus Current Opinion in Structural Biology. 9: 215-221. PMID 10322215 DOI: 10.1016/S0959-440X(99)80031-1  0.361
1999 Agrawal RK, Lata RK, Frank J. Conformational variability in Escherichia coli 70S ribosome as revealed by 3D cryo-electron microscopy. The International Journal of Biochemistry & Cell Biology. 31: 243-254. PMID 10216957 DOI: 10.1016/S1357-2725(98)00149-6  0.407
1999 McCutcheon JP, Agrawal RK, Philips SM, Grassucci RA, Gerchman SE, Clemons WM, Ramakrishnan V, Frank J. Location of translational initiation factor IF3 on the small ribosomal subunit. Proceedings of the National Academy of Sciences of the United States of America. 96: 4301-6. PMID 10200257 DOI: 10.1073/Pnas.96.8.4301  0.421
1999 Agrawal RK, Penczek P, Grassucci RA, Burkhardt N, Nierhaus KH, Frank J. Effect of buffer conditions on the position of tRNA on the 70 S ribosome as visualized by cryoelectron microscopy. Journal of Biological Chemistry. 274: 8723-8729. PMID 10085112 DOI: 10.1074/Jbc.274.13.8723  0.325
1999 Gabashvili IS, Agrawal RK, Grassucci R, Frank J. Structure and structural variations of the Escherichia coli 30 S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy. Journal of Molecular Biology. 286: 1285-91. PMID 10064696 DOI: 10.1006/Jmbi.1999.2538  0.773
1999 Manoj N, Srinivas VR, Surolia A, Vijayan M, Suguna K, Ravishankar R, Schwarzenbacher R, Zeth K, Diederichs, Kostner GM, Gries A, Laggner P, Prassl R, Madhusudan, Akamine P, ... ... Frank J, et al. Contributory presentations/posters Journal of Biosciences. 24: 33-198. DOI: 10.1007/Bf02989373  0.386
1998 Frank J. The ribosome - Structure and functional ligand-binding experiments using cryo-electron microscopy Journal of Structural Biology. 124: 142-150. PMID 10049802 DOI: 10.1006/Jsbi.1998.4071  0.427
1998 Ban N, Freeborn B, Nissen P, Penczek P, Grassucci RA, Sweet R, Frank J, Moore PB, Steitz TA. A 9 A resolution X-ray crystallographic map of the large ribosomal subunit. Cell. 93: 1105-15. PMID 9657144 DOI: 10.1016/S0092-8674(00)81455-5  0.352
1998 Malhotra A, Penczek P, Agrawal RK, Gabashvili IS, Grassucci RA, Jünemann R, Burkhardt N, Nierhaus KH, Frank J. Escherichia coli 70 S ribosome at 15 A resolution by cryo-electron microscopy: localization of fMet-tRNAfMet and fitting of L1 protein. Journal of Molecular Biology. 280: 103-16. PMID 9653034 DOI: 10.1006/Jmbi.1998.1859  0.805
1998 Agrawal RK, Penczek PA, Grassucci RA, Frank J. Visualization of elongation factor G on the Escherichia coli 70S ribosome: The mechanism of translocation Proceedings of the National Academy of Sciences of the United States of America. 95: 6134-6138. PMID 9600930 DOI: 10.1073/Pnas.95.11.6134  0.397
1998 Samsó M, Radermacher M, Frank J, Koonce MP. Structural characterization of a dynein motor domain. Journal of Molecular Biology. 276: 927-37. PMID 9566197 DOI: 10.1006/Jmbi.1997.1584  0.367
1998 Frank J, Agrawal RK. The movement of tRNA through the ribosome. Biophysical Journal. 74: 589-594. PMID 9449359 DOI: 10.1016/S0006-3495(98)77817-8  0.343
1998 Verschoor A, Warner JR, Srivastava S, Grassucci RA, Frank J. Three-dimensional structure of the yeast ribosome Nucleic Acids Research. 26: 655-661. PMID 9421530 DOI: 10.1093/Nar/26.2.655  0.393
1998 Frank J, Penczek P, Malhotra A, Gabashvili I, Grassucci R, Heagle A, Srivastava S, Burkhardt N, Jünemann R, Nierhaus KH, Agrawal RK. The Ribosome - Three-Dimensional Structure and Ligand-Binding Studies Microscopy and Microanalysis. 4: 962-963. DOI: 10.1017/S1431927600024934  0.729
1997 Beckmann R, Bubeck D, Grassucci R, Penczek P, Verschoor A, Blobel G, Frank J. Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex. Science (New York, N.Y.). 278: 2123-6. PMID 9405348 DOI: 10.1126/Science.278.5346.2123  0.407
1997 Zhu J, Penczek PA, Schröder R, Frank J. Three-Dimensional Reconstruction with Contrast Transfer Function Correction from Energy-Filtered Cryoelectron Micrographs: Procedure and Application to the 70S Escherichia coli Ribosome Journal of Structural Biology. 118: 197-219. PMID 9169230 DOI: 10.1006/Jsbi.1997.3845  0.306
1997 Frank J. The ribosome at higher resolution--the donut takes shape. Current Opinion in Structural Biology. 7: 266-272. PMID 9094327 DOI: 10.1016/S0959-440X(97)80035-8  0.372
1997 Wadzack J, Burkhardt N, Jünemann R, Diedrich G, Nierhaus KH, Frank J, Penczek P, Meerwinck W, Schmitt M, Willumeit R, Stuhrmann HB. Direct localization of the tRNAs within the elongating ribosome by means of neutron scattering (proton-spin contrast-variation). Journal of Molecular Biology. 266: 343-56. PMID 9047368 DOI: 10.1006/Jmbi.1996.0788  0.316
1996 Lata KR, Agrawal RK, Penczek P, Grassucci R, Zhu J, Frank J. Three-dimensional reconstruction of the Escherichia coli 30 S ribosomal subunit in ice. Journal of Molecular Biology. 262: 43-52. PMID 8809178 DOI: 10.1006/Jmbi.1996.0497  0.326
1996 Marabini R, Vaquerizo C, Fernández JJ, Carazo JM, Engel A, Frank J. Proposal for a new distributed database of macromolecular and subcellular structures from different areas of microscopy. Journal of Structural Biology. 116: 161-5. PMID 8742739 DOI: 10.1006/Jsbi.1996.0026  0.754
1996 Verschoor A, Srivastava S, Grassucci R, Frank J. Native 3D structure of eukaryotic 80s ribosome: morphological homology with E. coli 70S ribosome. Journal of Cell Biology. 133: 495-505. PMID 8636226 DOI: 10.1083/Jcb.133.3.495  0.36
1996 Agrawal RK, Penczek PA, Grassucci RA, Li Y, Leith A, Nierhaus KH, Frank J. Direct Visualization of A-, P-, and E-Site Transfer RNAs in the Escherichia coli Ribosome Science. 271: 1000-1002. PMID 8584922 DOI: 10.1126/Science.271.5251.1000  0.347
1996 Liu W, Boisset N, Frank J. Estimation of variance distribution in three-dimensional reconstruction. II. Applications. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 12: 2628-35. PMID 7500222 DOI: 10.1364/Josaa.12.002628  0.664
1995 Frank J, Verschoor A, Li Y, Zhu J, Lata RK, Radermacher M, Penczek PA, Grassucci R, Agrawal RK, Srivastava S. A Model Of The Translational Apparatus Based On A Three-Dimensional Reconstruction Of The Escherichia Coli Ribosome Biochemistry and Cell Biology. 73: 757-765. PMID 8721992 DOI: 10.1139/O95-084  0.337
1995 Srivastava S, Verschoor A, Radermacher M, Grassucci R, Frank J. Three-dimensional reconstruction of mammalian 40 S ribosomal subunit embedded in ice. Journal of Molecular Biology. 245: 461-466. PMID 7844819 DOI: 10.1006/Jmbi.1994.0037  0.373
1995 Frank J. Approaches to large-scale structures Current Opinion in Structural Biology. 5: 194-201. PMID 7648321 DOI: 10.1016/0959-440X(95)80075-1  0.327
1995 Frank J, Zhu J, Penczek PA, Li Y, Srivastava S, Verschoor A, Radermacher M, Grassucci R, Lata RK, Agrawal RK. A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome Nature. 376: 441-444. PMID 7630422 DOI: 10.1038/376441A0  0.41
1995 Boisset N, Penczek PA, Taveau JC, Lamy J, Frank J, Lamy J. Three-dimensional reconstruction of Androctonus australis hemocyanin labeled with a monoclonal Fab fragment. Journal of Structural Biology. 115: 16-29. PMID 7577229 DOI: 10.1006/Jsbi.1995.1025  0.666
1995 Lata KR, Penczek PA, Frank J. Automatic particle picking from electron micrographs. Ultramicroscopy. 58: 381-391. PMID 7571118 DOI: 10.1016/0304-3991(95)00002-I  0.3
1994 Mannella CA, Marko M, Penczek P, Barnard D, Frank J. The internal compartmentation of rat-liver mitochondria: Tomographic study using the high-voltage transmission electron microscope Microscopy Research and Technique. 27: 278-283. PMID 8186446 DOI: 10.1002/Jemt.1070270403  0.596
1994 Penczek PA, Grassucci RA, Frank J. The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles. Ultramicroscopy. 53: 251-270. PMID 8160308 DOI: 10.1016/0304-3991(94)90038-8  0.355
1994 Lambert O, Boisset N, Penczek PA, Lamy J, Taveau JC, Frank J, Lamy JN. Quaternary structure of Octopus vulgaris hemocyanin. Three-dimensional reconstruction from frozen-hydrated specimens and intramolecular location of functional units Ove and Ovb. Journal of Molecular Biology. 238: 75-87. PMID 8145258 DOI: 10.1006/Jmbi.1994.1269  0.672
1994 Radermacher M, Rao V, Grassucci R, Frank J, Timerman AP, Fleischer S, Wagenknecht T. Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle Journal of Cell Biology. 127: 411-423. PMID 7929585 DOI: 10.1083/Jcb.127.2.411  0.346
1994 Boisset N, Penczek P, Pochon F, Frank J, Lamy J. Three‐Dimensional Reconstruction of Human α2‐Macroglobulin and Refinement of the Localization of Thiol Ester Bonds with Monomaleimido Nanogolda Annals of the New York Academy of Sciences. 737: 229-244. PMID 7524399 DOI: 10.1111/J.1749-6632.1994.Tb44315.X  0.615
1993 Frank J, Chiu W, Henderson R. Flopping polypeptide chains and Suleika's subtle imperfections: analysis of variations in the electron micrograph of a purple membrane crystal. Ultramicroscopy. 49: 387-96. PMID 8475603 DOI: 10.1016/0304-3991(93)90244-R  0.467
1993 McEwen BF, Arena JT, Frank J, Rieder CL. Structure of the colcemid-treated PtK1 kinetochore outer plate as determined by high voltage electron microscopic tomography. The Journal of Cell Biology. 120: 301-12. PMID 8421050 DOI: 10.1083/Jcb.120.2.301  0.304
1993 Boisset N, Radermacher M, Grassucci R, Taveau J, Liu W, Lamy J, Frank J, Lamy JN. Three-dimensional immunoelectron microscopy of scorpion hemocyanin labeled with a monoclonal Fab fragment. Journal of Structural Biology. 111: 234-244. PMID 8003384 DOI: 10.1006/Jsbi.1993.1053  0.67
1993 Boisset N, Penczek P, Pochon F, Frank J, Lamy J. Three-dimensional Architecture of Human α2-Macroglobulin Transformed with Methylamine Journal of Molecular Biology. 232: 522-529. PMID 7688427 DOI: 10.1006/Jmbi.1993.1408  0.651
1992 Srivastava S, Verschoor A, Frank J. Eukaryotic initiation factor 3 does not prevent association through physical blockage of the ribosomal subunit-subunit interface Journal of Molecular Biology. 226: 301-304. PMID 1640449 DOI: 10.1016/0022-2836(92)90946-H  0.355
1992 Morgan DG, Grant RA, Chiu W, Frank J. Patch averaging of electron images of GP32*I crystals with variable thickness Journal of Structural Biology. 108: 245-256. PMID 1335748 DOI: 10.1016/1047-8477(92)90025-6  0.455
1992 Radermacher M, Wagenknecht T, Grassucci R, Frank J, Iniu M, Chadwick C, Fleischer S. Cryo-EM of the native structure of the calcium release channel/ryanodine receptor from sarcoplasmic reticulum Biophysical Journal. 61: 936-940. PMID 1316182 DOI: 10.1016/S0006-3495(92)81900-8  0.311
1992 Boisset N, Grassucci R, Penczek P, Delain E, Pochon F, Frank J, Lamy JN. Three-dimensional reconstruction of a complex of human α2-macroglobulin with monomaleimido nanogold (Au1.4nm) embedded in ice Journal of Structural Biology. 109: 39-45. PMID 1283687 DOI: 10.1016/1047-8477(92)90065-I  0.656
1992 Penczek PA, Radermacher M, Frank J. Three-dimensional reconstruction of single particles embedded in ice. Ultramicroscopy. 40: 33-53. DOI: 10.1016/0304-3991(92)90233-A  0.309
1991 Frank J, Penczek P, Grassucci R, Srivastava S. Three-dimensional reconstruction of the 70S Escherichia coli ribosome in ice: the distribution of ribosomal RNA. Journal of Cell Biology. 115: 597-605. PMID 1918155 DOI: 10.1083/Jcb.115.3.597  0.388
1990 Verschoor A, Frank J. Three-dimensional structure of the mammalian cytoplasmic ribosome. Journal of Molecular Biology. 214: 737-749. PMID 2388265 DOI: 10.1016/0022-2836(90)90289-X  0.402
1990 Boisset N, Taveau JC, Lamy J, Wagenknecht T, Radermacher M, Frank J. Three-dimensional reconstruction of native Androctonus australis hemocyanin Journal of Molecular Biology. 216: 743-760. PMID 2258938 DOI: 10.1016/0022-2836(90)90396-4  0.665
1990 Carazo JM, Rivera FF, Zapata EL, Radermacher M, Frank J. Fuzzy sets-based classification of electron microscopy images of biological macromolecules with an application to ribosomal particles. Journal of Microscopy. 157: 187-203. PMID 2179560 DOI: 10.1111/J.1365-2818.1990.Tb02958.X  0.647
1989 Frank J, Chiu W, Degn L. The characterization of structural variations within a crystal field. Ultramicroscopy. 26: 345-60. PMID 3238812 DOI: 10.1016/0304-3991(88)90234-3  0.454
1989 Verschoor A, Zhang NY, Wagenknecht T, Obrig T, Radermacher M, Frank J. Three-dimensional reconstruction of mammalian 40 S ribosomal subunit Journal of Molecular Biology. 209: 115-126. PMID 2810364 DOI: 10.1016/0022-2836(89)90175-7  0.38
1989 Carazo JM, Wagenknecht T, Frank J. Variations of the three-dimensional structure of the Escherichia coli ribosome in the range of overlap views. An application of the methods of multicone and local single-cone three-dimensional reconstruction Biophysical Journal. 55: 465-477. PMID 2649164 DOI: 10.1016/S0006-3495(89)82840-1  0.699
1989 Wagenknecht T, Carazo JM, Radermacher M, Frank J. Three-dimensional reconstruction of the ribosome from Escherichia coli Biophysical Journal. 55: 455-464. PMID 2649163 DOI: 10.1016/S0006-3495(89)82839-5  0.711
1989 Wagenknecht T, Grassucci R, Frank J, Saito A, Inui M, Fleischer S. Three-dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum Nature. 338: 167-170. PMID 2537473 DOI: 10.1038/338167A0  0.315
1989 Frank J. Image analysis of single macromolecules Electron Microscopy Reviews. 2: 53-74. PMID 2491342 DOI: 10.1016/0892-0354(89)90010-5  0.366
1988 Carazo JM, Frank J. Three-dimensional matching of macromolecular structures obtained from electron microscopy: an application to the 70S and 50S E. coli ribosomal particles. Ultramicroscopy. 25: 13-22. PMID 3291355 DOI: 10.1016/0304-3991(88)90401-9  0.695
1988 Frank J, Verschoor A, Wagenknecht T, Radermacher M, Carazo JM. A new non-crystallographic image-processing technique reveals the architecture of ribosomes Trends in Biochemical Sciences. 13: 123-127. PMID 3075375 DOI: 10.1016/0968-0004(88)90063-1  0.704
1988 Frank J, Radermacher M, Wagenknecht T, Verschoor A. Studying ribosome structure by electron microscopy and computer-image processing Methods in Enzymology. 164: 3-35. PMID 3071670 DOI: 10.1016/S0076-6879(88)64032-8  0.393
1988 Wagenknecht T, Frank J, Boublik M, Nurse K, Ofengand J. Direct localization of the tRNA-anticodon interaction site on the Escherichia coli 30 S ribosomal subunit by electron microscopy and computerized image averaging Journal of Molecular Biology. 203: 753-760. PMID 3062179 DOI: 10.1016/0022-2836(88)90207-0  0.404
1988 Carazo JM, Wagenknecht T, Radermacher M, Mandiyan V, Boublik M, Frank J. Three-dimensional structure of 50 S Escherichia coli ribosomal subunits depleted of proteins L7/L12 Journal of Molecular Biology. 201: 393-404. PMID 3047401 DOI: 10.1016/0022-2836(88)90146-5  0.713
1988 Frank J, Bretaudiere JP, Carazo JM, Verschoor A, Wagenknecht T. Classification of images of biomolecular assemblies: a study of ribosomes and ribosomal subunits of Escherichia coli Journal of Microscopy. 150. PMID 3045323 DOI: 10.1111/J.1365-2818.1988.Tb04602.X  0.686
1988 Boisset N, Frank J, Taveau JC, Billiald P, Motta G, Lamy J, Sizaret PY, Lamy J. Intermolecular localization of epitopes within an oligomeric protein by immunoelectron microscopy and image processing Proteins. 3: 161-183. PMID 2474818 DOI: 10.1002/Prot.340030305  0.679
1988 Saito A, Inui M, Radermacher M, Frank J, Fleischer S. Ultrastructure of the calcium release channel of sarcoplasmic reticulum. Journal of Cell Biology. 107: 211-219. PMID 2455723 DOI: 10.1083/Jcb.107.1.211  0.337
1988 Wagenknecht T, Grassucci R, Frank J. Electron microscopy and computer image averaging of ice-embedded large ribosomal subunits from Escherichia coli Journal of Molecular Biology. 199: 137-147. PMID 2451023 DOI: 10.1016/0022-2836(88)90384-1  0.396
1987 Radermacher M, Wagenknecht T, Verschoor A, Frank J. Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli Journal of Microscopy. 146. PMID 3302267 DOI: 10.1111/J.1365-2818.1987.Tb01333.X  0.343
1987 Mannella CA, Frank J, Delihas N. Interrelatedness of 5S RNA sequences investigated by correspondence analysis. Journal of Molecular Evolution. 24: 228-235. PMID 3106638 DOI: 10.1007/Bf02111236  0.574
1987 Mannella CA, Ribeiro AJ, Frank J. Cytochrome c binds to lipid domains in arrays of mitochondrial outer membrane channels. Biophysical Journal. 51: 221-6. PMID 3030457 DOI: 10.1016/S0006-3495(87)83327-1  0.573
1987 Frank J, McEwen BF, Radermacher M, Turner JN, Rieder CL. Three-dimensional tomographic reconstruction in high voltage electron microscopy Journal of Electron Microscopy Technique. 6: 193-205. DOI: 10.1002/Jemt.1060060210  0.309
1987 Radermacher M, Wagenknecht T, Verschoor A, Frank J. Three-dimensional structure of the large ribosomal subunit from Escherichia coli. The Embo Journal. 6: 1107-1114. DOI: 10.1002/J.1460-2075.1987.Tb04865.X  0.433
1986 Frank J, Verschoor A, Wagenknecht T, Radermacher M, Rosenthal M, Boublik M. New strategies for determining ribosomal subunit structure from electron micrographs by single particle averaging methods. Biophysical Journal. 49: 9-11. PMID 19431662 DOI: 10.1016/S0006-3495(86)83571-8  0.369
1986 Mannella CA, Ribeiro A, Frank J. Structure of the Channels in the Outer Mitochondrial Membrane: Electron Microscopic Studies of the Periodic Arrays Induced by Phospholipase a2 Treatment of the Neurospora membrane Biophysical Journal. 49: 307-318. PMID 19431637 DOI: 10.1016/S0006-3495(86)83643-8  0.585
1986 Verschoor A, Frank J, Wagenknecht T, Boublik M. Computer-averaged views of the 70 S monosome from Escherichia coli Journal of Molecular Biology. 187: 581-590. PMID 3519978 DOI: 10.1016/0022-2836(86)90336-0  0.304
1986 McEwen BF, Radermacher M, Rieder CL, Frank J. Tomographic three-dimensional reconstruction of cilia ultrastructure from thick sections. Proceedings of the National Academy of Sciences of the United States of America. 83: 9040-9044. PMID 3466176 DOI: 10.1073/Pnas.83.23.9040  0.317
1986 Mannella CA, Frank J. Effect of succinylation on images of negatively stained arrays of mitochondrial outer membrane channels. Journal of Ultrastructure and Molecular Structure Research. 96: 31-40. PMID 2445865 DOI: 10.1016/0889-1605(86)90005-4  0.563
1986 Tsuji M, Frank J, Manley RSJ. Image analysis in the electron microscopy of cellulose protofibrils. II: Digital correlation methods Colloid and Polymer Science. 264: 89-96. DOI: 10.1007/Bf01410311  0.333
1985 Verschoor A, Frank J, Boublik M. Investigation of the 50 S ribosomal subunit by electron microscopy and image analysis. Journal of Ultrastructure Research. 92: 180-189. PMID 3913778 DOI: 10.1016/0889-1605(85)90045-X  0.318
1985 Kim CH, Radermacher M, Kessel M, Frank J, King TE. Three-dimensional reconstruction of cytochrome oxidase vesicle crystals prepared by cholate solubilization. Journal of Inorganic Biochemistry. 23: 163-9. PMID 2991453 DOI: 10.1016/0162-0134(85)85021-2  0.304
1984 Mannella CA, Frank J. Electron Microscopic Stains as Probes of the Surface Charge of Mitochondrial Outer Membrane Channels Biophysical Journal. 45: 139-141. PMID 19431542 DOI: 10.1016/S0006-3495(84)84140-5  0.6
1984 Woodcock CLF, Frank J. Nucleosome mass distribution using image averaging Journal of Ultrastructure Research. 89: 295-302. PMID 6544891 DOI: 10.1016/S0022-5320(84)80045-3  0.307
1984 Radermacher M, Frank J. Representation of three-dimensionally reconstructed objects in electron microscopy by surfaces of equal density. Journal of Microscopy. 136: 77-85. PMID 6392559 DOI: 10.1111/J.1365-2818.1984.Tb02547.X  0.329
1984 Verschoor A, Frank J, Radermacher M, Wagenknecht T, Boublik M. Three-dimensional reconstruction of the 30 S ribosomal subunit from randomly oriented particles Journal of Molecular Biology. 178: 677-695. PMID 6387155 DOI: 10.1016/0022-2836(84)90245-6  0.317
1984 Wagenknecht T, Frank J. Localization of lipoyl-bearing domains in the α-ketoglutarate dehydrogenase multienzyme complex Biochemistry. 23: 3383-3389. PMID 6380587 DOI: 10.1021/Bi00310A001  0.359
1984 Mannella CA, Frank J. Negative staining characteristics of arrays of mitochondrial pore protein: use of correspondence analysis to classify different staining patterns. Ultramicroscopy. 13: 93-102. PMID 6206632 DOI: 10.1016/0304-3991(84)90060-3  0.579
1984 Frank J. The role of multivariate image analysis in solving the architecture of the limulus polyphemus hemocyanin molecule Ultramicroscopy. 13: 153-164. DOI: 10.1016/0304-3991(84)90065-2  0.325
1983 Frank J, van Heel M. Correspondence analysis of aligned images of biological particles. Journal of Molecular Biology. 161: 134-7. PMID 7154073 DOI: 10.1016/0022-2836(82)90282-0  0.58
1983 Mannella CA, Colombini M, Frank J. Structural and functional evidence for multiple channel complexes in the outer membrane of Neurospora crassa mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 80: 2243-7. PMID 6300902 DOI: 10.1073/Pnas.80.8.2243  0.571
1982 Mannella CA, Frank J. Effects of divalent metal ions and chelators on the structure of outer mitochondrial membranes from neurospora crassa. Biophysical Journal. 37: 3-4. PMID 19431484 DOI: 10.1016/S0006-3495(82)84569-4  0.545
1982 Lamy J, Sizaret PY, Frank J, Verschoor A, Feldmann R, Bonaventura J. Architecture of Limulus polyphemus hemocyanin. Biochemistry. 21: 6825-33. PMID 7159564 DOI: 10.1021/Bi00269A031  0.315
1982 Zingsheim HP, Barrantes FJ, Frank J, Hänicke W, Neugebauer DC. Direct structural localization of two toxin-recognition sites on an ACh receptor protein Nature. 299: 81-84. PMID 7110329 DOI: 10.1038/299081A0  0.321
1982 Frank J, Verschoor A, Boublik M. Multivariate statistical analysis of ribosome electron micrographs. L and R lateral views of the 40 S subunit from HeLa cells. Journal of Molecular Biology. 161: 107-133. PMID 6185684 DOI: 10.1016/0022-2836(82)90281-9  0.312
1982 Zingsheim HP, Neugebauer DC, Frank J, Hänicke W, Barrantes FJ. Dimeric arrangement and structure of the membrane-bound acetylcholine receptor studied by electron microscopy. The Embo Journal. 1: 541-547. DOI: 10.1002/J.1460-2075.1982.Tb01206.X  0.358
1981 Frank J, Verschoor A, Boublik M. Computer Averaging of Electron Micrographs of 40S Ribosomal Subunits Science. 214: 1353-1355. PMID 7313694 DOI: 10.1126/Science.7313694  0.371
1981 Frank J. Three-dimensional reconstruction of single molecules Methods in Cell Biology. 22: 325-344. PMID 7022121 DOI: 10.1016/S0091-679X(08)61882-8  0.303
1981 Frank J, Shimkin B, Dowse H. SPIDER—A modular software system for electron image processing Ultramicroscopy. 6: 343-357. DOI: 10.1016/S0304-3991(81)80221-5  0.318
1981 Frank J. chapter 12 Introduction Methods in Cell Biology. 22: 199-213. DOI: 10.1016/S0091-679X(08)61878-6  0.307
1980 Zingsheim HP, Neugebauer -Ch. D, Barrantes FJ, Frank J. Structural details of membrane-bound acetylcholine receptor from Torpedo marmorata Proceedings of the National Academy of Sciences of the United States of America. 77: 952-956. PMID 6928692 DOI: 10.1073/Pnas.77.2.952  0.33
1979 Frank J. Image Analysis In Electron Microscopy Journal of Microscopy. 117: 25-38. DOI: 10.1111/J.1365-2818.1979.Tb00229.X  0.323
1975 Frank J. Controlled focusing and stigmating in the conventional and scanning transmission electron microscope Journal of Physics E: Scientific Instruments. 8: 582-587. DOI: 10.1088/0022-3735/8/7/014  0.323
1969 Hoppe W, Langer R, Frank J, Feltynowski A. [Image differentiation procedures in electron microscopy]. Die Naturwissenschaften. 56: 267-72. PMID 5360874 DOI: 10.1007/Bf00633921  0.548
1969 Langer R, Formanek S, Frank J, Martin HH, Hoppe W. [Structure of the murein sacculus of Spirillum serpens. Quantitative electron microscopy studies at high resolution]. Hoppe-Seyler's Zeitschrift FüR Physiologische Chemie. 350: 1173-4. PMID 5352337  0.544
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