Year |
Citation |
Score |
2022 |
Patel JR, Oh J, Wang S, Crawford JM, Isaacs FJ. Cross-kingdom expression of synthetic genetic elements promotes discovery of metabolites in the human microbiome. Cell. PMID 35366417 DOI: 10.1016/j.cell.2022.03.008 |
0.667 |
|
2020 |
Goddard T, Patel JR, Park HB, Crawford JM. Dimeric Stilbene Antibiotics Target the Bacterial Cell Wall in Drug-resistant Gram-positive Pathogens. Biochemistry. PMID 32410442 DOI: 10.1021/Acs.Biochem.0C00213 |
0.679 |
|
2020 |
Park HB, Goddard TN, Oh J, Patel J, Wei Z, Perez CE, Mercado BQ, Wang R, Wyche TP, Piizzi G, Flavell RA, Crawford J. Bacterial Autoimmune Drug Metabolism Transforms an Immunomodulator into Structurally and Functionally Divergent Antibiotics. Angewandte Chemie (International Ed. in English). PMID 32097515 DOI: 10.1002/Anie.201916204 |
0.624 |
|
2018 |
Shine EE, Xue M, Patel JR, Healy AR, Surovtseva YV, Herzon SB, Crawford JM. Model colibactins exhibit human cell genotoxicity in the absence of host bacteria. Acs Chemical Biology. PMID 30403848 DOI: 10.1021/Acschembio.8B00714 |
0.673 |
|
2018 |
Oh J, Patel J, Park HB, Crawford JM. β-lactam Biotransformations Activate Innate Immunity. The Journal of Organic Chemistry. PMID 29616809 DOI: 10.1021/Acs.Joc.8B00241 |
0.694 |
|
2018 |
Martin RW, Des Soye BJ, Kwon YC, Kay J, Davis RG, Thomas PM, Majewska NI, Chen CX, Marcum RD, Weiss MG, Stoddart AE, Amiram M, Ranji Charna AK, Patel JR, Isaacs FJ, et al. Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids. Nature Communications. 9: 1203. PMID 29572528 DOI: 10.1038/S41467-018-03469-5 |
0.316 |
|
2018 |
Patel J, Crawford JM. Microbiota-Regulated Outcomes of Human Cancer Immunotherapy via the PD-1/PD-L1 Axis. Biochemistry. PMID 29350031 DOI: 10.1021/Acs.Biochem.7B01249 |
0.477 |
|
2016 |
Healy AR, Nikolayevskiy H, Patel JR, Crawford JM, Herzon SB. A Mechanistic Model for Colibactin-Induced Genotoxicity. Journal of the American Chemical Society. 138: 15563-15570. PMID 27934011 DOI: 10.1021/Jacs.6B10354 |
0.564 |
|
2015 |
Des Soye BJ, Patel JR, Isaacs FJ, Jewett MC. Repurposing the translation apparatus for synthetic biology. Current Opinion in Chemical Biology. 28: 83-90. PMID 26186264 DOI: 10.1016/J.Cbpa.2015.06.008 |
0.311 |
|
2015 |
Rovner AJ, Haimovich AD, Katz SR, Li Z, Grome MW, Gassaway BM, Amiram M, Patel JR, Gallagher RR, Rinehart J, Isaacs FJ. Recoded organisms engineered to depend on synthetic amino acids. Nature. 518: 89-93. PMID 25607356 DOI: 10.1038/Nature14095 |
0.324 |
|
2015 |
Gallagher RR, Patel JR, Interiano AL, Rovner AJ, Isaacs FJ. Multilayered genetic safeguards limit growth of microorganisms to defined environments. Nucleic Acids Research. 43: 1945-54. PMID 25567985 DOI: 10.1093/Nar/Gku1378 |
0.341 |
|
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