Robert S. Paton - Publications

Affiliations: 
Organic Chemistry University of Oxford, Oxford, United Kingdom 
 2018- Chemistry Colorado State University, Fort Collins, CO 
Area:
Computational organic chemistry
Website:
http://patonlab.com

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ascough DMH, Duarte F, Paton RS. Stereospecific 1,3-H Transfer of Indenols Proceeds via Persistent Ion-Pairs Anchored By NH··· Pi Interactions. Journal of the American Chemical Society. PMID 30338998 DOI: 10.1021/jacs.8b09874  1
2018 Anderson EA, Paton RS. Selectivity in Transition Metal-catalyzed Cyclizations: Insights from Experiment and Theory. Chimia. 72: 614-620. PMID 30257737 DOI: 10.2533/chimia.2018.614  0.56
2018 Dixon DJ, Franchino A, Chapman J, Funes-Ardoiz I, Paton R. Catalytic Enantio- and Diastereoselective Mannich Addition of TosMIC to Ketimines. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30246415 DOI: 10.1002/chem.201804099  1
2018 Galan SRG, Wickens JR, Dadova J, Ng WL, Zhang X, Simion RA, Quinlan R, Pires E, Paton RS, Caddick S, Chudasama V, Davis BG. Post-translational site-selective protein backbone α-deuteration. Nature Chemical Biology. 14: 955-963. PMID 30224694 DOI: 10.1038/s41589-018-0128-y  0.16
2018 Formica M, Sorin G, Farley AJM, Díaz J, Paton RS, Dixon DJ. Bifunctional iminophosphorane catalysed enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles. Chemical Science. 9: 6969-6974. PMID 30210771 DOI: 10.1039/c8sc01804a  1
2018 Pupo G, Ibba F, Ascough DMH, Vicini AC, Ricci P, Christensen KE, Pfeifer L, Morphy JR, Brown JM, Paton RS, Gouverneur V. Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis. Science (New York, N.Y.). 360: 638-642. PMID 29748281 DOI: 10.1126/science.aar7941  1
2018 Tan JSJ, Hirvonen V, Paton RS. Dynamic Intermediates in the Radical Cation Diels-Alder Cycloaddition: Lifetime and Suprafacial Stereoselectivity. Organic Letters. PMID 29741386 DOI: 10.1021/acs.orglett.8b00737  0.64
2018 Kumar K, Woo SM, Siu T, Cortopassi WA, Duarte F, Paton RS. Cation-π interactions in protein-ligand binding: theory and data-mining reveal different roles for lysine and arginine. Chemical Science. 9: 2655-2665. PMID 29719674 DOI: 10.1039/c7sc04905f  1
2018 Ardkhean R, Mortimore M, Paton RS, Fletcher SP. Formation of quaternary centres by copper catalysed asymmetric conjugate addition to β-substituted cyclopentenones with the aid of a quantitative structure-selectivity relationship. Chemical Science. 9: 2628-2632. PMID 29675255 DOI: 10.1039/c7sc05304e  0.24
2018 Johnson TC, Elbert BL, Farley AJM, Gorman TW, Genicot C, Lallemand B, Pasau P, Flasz J, Castro JL, MacCoss M, Dixon DJ, Paton RS, Schofield CJ, Smith MD, Willis MC. Direct sulfonylation of anilines mediated by visible light. Chemical Science. 9: 629-633. PMID 29629128 DOI: 10.1039/c7sc03891g  1
2018 Al Temimi AHK, Belle R, Kumar K, Poater J, Betlem P, Pieters BJGE, Paton RS, Bickelhaupt FM, Mecinović J. Recognition of shorter and longer trimethyllysine analogues by epigenetic reader proteins. Chemical Communications (Cambridge, England). PMID 29457186 DOI: 10.1039/c8cc01009a  1
2017 Lohans CT, van Groesen E, Kumar K, Tooke CL, Spencer J, Paton RS, Brem J, Schofield C. A New Mechanism for β-Lactamases: Class D Enzymes Degrade 1β-Methyl Carbapenems via Lactone Formation. Angewandte Chemie (International Ed. in English). PMID 29236332 DOI: 10.1002/anie.201711308  1
2017 Kim D, Kim B, Sohn TI, Paton RS. Asymmetric Total Syntheses and Structure Confirmation of Chlorofucins and Bromofucins. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29222867 DOI: 10.1002/chem.201704564  0.4
2017 Belle R, Al Temimi AHK, Kumar K, Pieters BJGE, Tumber A, Dunford JE, Johansson C, Oppermann U, Brown T, Schofield CJ, Hopkinson RJ, Paton RS, Kawamura A, Mecinović J. Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition. Chemical Communications (Cambridge, England). 53: 13264-13267. PMID 29186216 DOI: 10.1039/c7cc08028j  1
2017 Shi H, Michaelides IN, Darses B, Jakubec P, Nguyen QNN, Paton RS, Dixon DJ. Total synthesis of (-)-himalensine A. Journal of the American Chemical Society. PMID 29120635 DOI: 10.1021/jacs.7b10956  1
2017 Jeong D, Sohn TI, Kim JY, Kim G, Kim D, Paton RS. Construction of 6,10-syn- and -anti-2,5-Dioxabicyclo[2.2.1]heptane Skeletons via Oxonium Ion Formation/Fragmentation: Prediction of Structure of (E)-Ocellenyne by NMR Calculation. Organic Letters. PMID 29112433 DOI: 10.1021/acs.orglett.7b03226  0.4
2017 Li Y, Jackson KE, Charlton A, Le Neve-Foster B, Khurshid A, Rudy HA, Thompson AL, Paton RS, Hodgson DM. Asymmetric Induction in C-Alkylation of Tropane-Derived Enamines: Congruence Between Computation and Experiment. The Journal of Organic Chemistry. PMID 28952729 DOI: 10.1021/acs.joc.7b01954  0.6
2017 Elbert B, Farley A, Gorman T, Johnson T, Genicot C, Lallemand B, Pasau P, Flasz J, Castro J, Maccoss M, Paton R, Schofield C, Smith M, Willis M, Dixon DJ. A C-H Cyanation of 6-Ring N-Containing Heteroaromatics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28833674 DOI: 10.1002/chem.201703931  1
2017 Mekareeya A, Walker PR, Couce-Rios A, Campbell CD, Steven A, Paton RS, Anderson EA. Mechanistic Insight into Palladium-Catalyzed Cycloisomerization: A Combined Experimental and Theoretical Study. Journal of the American Chemical Society. PMID 28699749 DOI: 10.1021/jacs.7b05436  1
2017 Pliotas C, Grayer SC, Ekkerman S, Chan AK, Healy J, Marius P, Bartlett W, Khan A, Cortopassi WA, Chandler SA, Rasmussen T, Benesch JL, Paton RS, Claridge TDW, Miller S, et al. AMP binding stabilizes the KTN domain of the Shewanella denitrificans Kef potassium efflux system. Biochemistry. PMID 28656748 DOI: 10.1021/acs.biochem.7b00300  1
2017 Smith MD, Münster N, Parker N, van Dijk L, Paton R. Visible light photocatalysis of 6π heterocyclization. Angewandte Chemie (International Ed. in English). PMID 28640479 DOI: 10.1002/anie.201705333  0.48
2017 Duarte F, Paton RS. Molecular Recognition in Asymmetric Counteranion Catalysis: Understanding Chiral Phosphate-Mediated Desymmetrization. Journal of the American Chemical Society. PMID 28582626 DOI: 10.1021/jacs.7b02468  1
2017 Semakul N, Jackson KE, Paton RS, Rovis T. Heptamethylindenyl (Ind*) enables diastereoselective benzamidation of cyclopropenes via Rh(iii)-catalyzed C-H activation. Chemical Science. 8: 1015-1020. PMID 28451239 DOI: 10.1039/c6sc02587k  0.6
2017 Manzano R, Datta S, Paton RS, Dixon DJ. Enantioselective Silver and Amine Co-catalyzed Desymmetrizing Cycloisomerization of Alkyne-linked Cyclohexanones. Angewandte Chemie (International Ed. in English). PMID 28429384 DOI: 10.1002/anie.201612048  1
2017 Zhang Z, Smart TJ, Choi H, Hardy F, Lohans CT, Abboud MI, Richardson MSW, Paton RS, McDonough MA, Schofield CJ. Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate. Proceedings of the National Academy of Sciences of the United States of America. PMID 28420789 DOI: 10.1073/pnas.1617760114  0.44
2017 Piou T, Romanov-Michailidis F, Romanova-Michaelides M, Jackson KE, Semakul N, Taggart TD, Newell BS, Rithner CD, Paton RS, Rovis T. Correlating Reactivity and Selectivity to Cyclopentadienyl Ligand Properties in Rh(III)-Catalyzed C-H Activation Reactions: An Experimental and Computational Study. Journal of the American Chemical Society. PMID 28060499 DOI: 10.1021/jacs.6b11670  0.6
2016 Choi H, Min M, Peng Q, Kang D, Paton RS, Hong S. Unraveling innate substrate control in site-selective palladium-catalyzed C-H heterocycle functionalization. Chemical Science. 7: 3900-3909. PMID 30155034 DOI: 10.1039/c5sc04590h  1
2016 Deb A, Peng Q, Hazra A, Paton RS, Maiti D. Detailed Mechanistic Studies on Palladium Catalyzed Selective C-H Olefination with Aliphatic Alkenes: A Significant Influence of Proton Shuttling. Journal of the American Chemical Society. PMID 27997801 DOI: 10.1021/jacs.6b10309  1
2016 Cortopassi WA, Kumar K, Paton RS. Cation-π interactions in CREBBP bromodomain inhibition: an electrostatic model for small-molecule binding affinity and selectivity. Organic & Biomolecular Chemistry. PMID 27814427 DOI: 10.1039/c6ob02234k  1
2016 Peng Q, Duarte F, Paton RS. Computing organic stereoselectivity - from concepts to quantitative calculations and predictions. Chemical Society Reviews. PMID 27722685 DOI: 10.1039/c6cs00573j  1
2016 Kiss E, Campbell CD, Driver RW, Jolliffe JD, Lang R, Sergeieva T, Okovytyy S, Paton RS, Smith MD. A Counterion-Directed Approach to the Diels-Alder Paradigm: Cascade Synthesis of Tricyclic Fused Cyclopropanes. Angewandte Chemie (International Ed. in English). PMID 27714921 DOI: 10.1002/anie.201608534  0.48
2016 Cortopassi WA, Kumar K, Duarte F, Pimentel AS, Paton RS. Mechanisms of histone lysine-modifying enzymes: A computational perspective on the role of the protein environment. Journal of Molecular Graphics & Modelling. 67: 69-84. PMID 27258188 DOI: 10.1016/j.jmgm.2016.04.011  1
2016 Peng Q, Paton RS. Catalytic Control in Cyclizations: From Computational Mechanistic Understanding to Selectivity Prediction. Accounts of Chemical Research. PMID 27137131 DOI: 10.1021/acs.accounts.6b00084  1
2016 Choi H, Paton RS, Park H, Schofield CJ. Investigations on recyclisation and hydrolysis in avibactam mediated serine β-lactamase inhibition. Organic & Biomolecular Chemistry. PMID 27072755 DOI: 10.1039/c6ob00353b  0.44
2016 Johnston CP, Kothari A, Sergeieva T, Okovytyy SI, Jackson KE, Paton RS, Smith MD. Corrigendum: Catalytic enantioselective synthesis of indanes by a cation-directed 5-endo-trig cyclization. Nature Chemistry. 8: 281. PMID 26892563 DOI: 10.1038/nchem.2457  0.6
2016 Brand M, Measures AR, Wilson BG, Cortopassi WA, Alexander R, Höss M, Hewings DS, Rooney TP, Paton RS, Conway SJ. Correction to Small Molecule Inhibitors of Bromodomain-Acetyl-lysine Interactions. Acs Chemical Biology. PMID 26756254 DOI: 10.1021/acschembio.5b01065  1
2016 Straker RN, Peng Q, Mekareeya A, Paton RS, Anderson EA. Computational ligand design in enantio- and diastereoselective ynamide [5+2] cycloisomerization. Nature Communications. 7: 10109. PMID 26728968 DOI: 10.1038/ncomms10109  1
2015 Engle KM, Pfeifer L, Pidgeon GW, Giuffredi GT, Thompson AL, Paton RS, Brown JM, Gouverneur V. Coordination diversity in hydrogen-bonded homoleptic fluoride-alcohol complexes modulates reactivity. Chemical Science. 6: 5293-5302. PMID 29449931 DOI: 10.1039/c5sc01812a  1
2015 Cortopassi WA, Simion R, Honsby CE, França TC, Paton RS. Dioxygen Binding in the Active Site of Histone Demethylase JMJD2A and the Role of the Protein Environment. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26663343 DOI: 10.1002/chem.201504536  1
2015 Cortopassi WA, Simion R, Honsby CE, França TC, Paton RS. Dioxygen Binding in the Active Site of Histone Demethylase JMJD2A and the Role of the Protein Environment. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26577067 DOI: 10.1002/chem.201502983  1
2015 Jackson KE, Mortimer CL, Odell B, McKenna JM, Claridge TD, Paton RS, Hodgson DM. α- and α'-Lithiation-Electrophile Trapping of N-Thiopivaloyl and N-tert-Butoxythiocarbonyl α-Substituted Azetidines: Rationalization of the Regiodivergence Using NMR and Computation. The Journal of Organic Chemistry. 80: 9838-46. PMID 26401908 DOI: 10.1021/acs.joc.5b01804  1
2015 Sohn TI, Kim D, Paton RS. Substrate-Controlled Asymmetric Total Syntheses of Microcladallenes A, B, and C Based on the Proposed Structures. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26376617 DOI: 10.1002/chem.201502592  1
2015 Han J, Lu Z, Flach AL, Paton RS, Hammond GB, Xu B. Role of Hydrogen Bonding Acceptors in Organo-Enamine Catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26178248 DOI: 10.1002/chem.201502407  1
2015 Johnston CP, Kothari A, Sergeieva T, Okovytyy SI, Jackson KE, Paton RS, Smith MD. Erratum: Catalytic enantioselective synthesis of indanes by a cation-directed 5-endo-trig cyclization. Nature Chemistry. 7: 359. PMID 25803476 DOI: 10.1038/nchem.2210  0.6
2015 Kim S, Robichaud DJ, Beckham GT, Paton RS, Nimlos MR. Ethanol dehydration in HZSM-5 studied by density functional theory: evidence for a concerted process. The Journal of Physical Chemistry. A. 119: 3604-14. PMID 25802969 DOI: 10.1021/jp513024z  1
2015 Gammack Yamagata AD, Datta S, Jackson KE, Stegbauer L, Paton RS, Dixon DJ. Enantioselective desymmetrization of prochiral cyclohexanones by organocatalytic intramolecular Michael additions to α,β-unsaturated esters. Angewandte Chemie (International Ed. in English). 54: 4899-903. PMID 25727215 DOI: 10.1002/anie.201411924  1
2015 Simón L, Paton RS. Origins of asymmetric phosphazene organocatalysis: computations reveal a common mechanism for nitro- and phospho-aldol additions. The Journal of Organic Chemistry. 80: 2756-66. PMID 25658042 DOI: 10.1021/acs.joc.5b00063  1
2015 Brand M, Measures AM, Wilson BG, Cortopassi WA, Alexander R, Höss M, Hewings DS, Rooney TP, Paton RS, Conway SJ. Small molecule inhibitors of bromodomain-acetyl-lysine interactions. Acs Chemical Biology. 10: 22-39. PMID 25549280 DOI: 10.1021/cb500996u  1
2015 Tang B, Simion R, Paton RS. Thermal and photochemical mechanisms for cyclobutane formation in bielschowskysin biosynthesis Synlett. 26: 501-507. DOI: 10.1055/s-0034-1379893  1
2015 Engle KM, Pfeifer L, Pidgeon GW, Giuffredi GT, Thompson AL, Paton RS, Brown JM, Gouverneur V. Coordination diversity in hydrogen-bonded homoleptic fluoride-alcohol complexes modulates reactivity Chemical Science. 6: 5293-5302. DOI: 10.1039/c5sc01812a  0.44
2014 Johnston CP, Kothari A, Sergeieva T, Okovytyy SI, Jackson KE, Paton RS, Smith MD. Catalytic enantioselective synthesis of indanes by a cation-directed 5-endo-trig cyclization. Nature Chemistry. 7: 171-7. PMID 25615672 DOI: 10.1038/nchem.2150  0.44
2014 Rooney TP, Filippakopoulos P, Fedorov O, Picaud S, Cortopassi WA, Hay DA, Martin S, Tumber A, Rogers CM, Philpott M, Wang M, Thompson AL, Heightman TD, Pryde DC, Cook A, ... Paton RS, et al. A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction. Angewandte Chemie (International Ed. in English). 53: 6126-30. PMID 24821300 DOI: 10.1002/anie.201402750  1
2014 Knipe PC, Gredi?ak M, Cernijenko A, Paton RS, Smith MD. Phase-transfer-catalysed synthesis of pyrroloindolines and pyridoindolines by a hydrogen-bond-assisted isocyanide cyclization cascade. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 3005-9. PMID 24523244 DOI: 10.1002/chem.201400192  1
2014 Paton RS. Dissecting non-covalent interactions in oxazaborolidinium catalyzed cycloadditions of maleimides. Organic & Biomolecular Chemistry. 12: 1717-20. PMID 24513964 DOI: 10.1039/c4ob00009a  1
2014 Daniels DS, Jones AS, Thompson AL, Paton RS, Anderson EA. Ligand bite angle-dependent palladium-catalyzed cyclization of propargylic carbonates to 2-alkynyl azacycles or cyclic dienamides. Angewandte Chemie (International Ed. in English). 53: 1915-20. PMID 24505010 DOI: 10.1002/anie.201309162  1
2014 Hornsby CE, Paton RS. Natural product biosynthesis: It's all downhill from here. Nature Chemistry. 6: 88-9. PMID 24451579 DOI: 10.1038/nchem.1852  1
2014 Pham HV, Paton RS, Ross AG, Danishefsky SJ, Houk KN. Intramolecular Diels-Alder reactions of cycloalkenones: stereoselectivity, Lewis acid acceleration, and halogen substituent effects. Journal of the American Chemical Society. 136: 2397-403. PMID 24410341 DOI: 10.1021/ja410220w  1
2014 Kim S, Ståhlberg J, Sandgren M, Paton RS, Beckham GT. Quantum mechanical calculations suggest that lytic polysaccharide monooxygenases use a copper-oxyl, oxygen-rebound mechanism. Proceedings of the National Academy of Sciences of the United States of America. 111: 149-54. PMID 24344312 DOI: 10.1073/pnas.1316609111  1
2014 Kim G, Sohn TI, Kim D, Paton RS. Asymmetric total synthesis of (+)-bermudenynol, a C15 Laurencia metabolite with a vinyl chloride containing oxocene skeleton, through intramolecular amide enolate alkylation. Angewandte Chemie (International Ed. in English). 53: 272-6. PMID 24227662 DOI: 10.1002/anie.201308077  1
2014 Sturgeon MR, Kim S, Lawrence K, Paton RS, Chmely SC, Nimlos M, Foust TD, Beckham GT. A Mechanistic investigation of acid-catalyzed cleavage of aryl-ether linkages: Implications for lignin depolymerization in acidic environments Acs Sustainable Chemistry and Engineering. 2: 472-485. DOI: 10.1021/sc400384w  1
2013 Han J, Paton RS, Xu B, Hammond GB. Synthesis of Cyclic α-Aminophosphonates through Copper Catalyzed Enamine Activation. Synthesis. 45: 463-470. PMID 24501432 DOI: 10.1055/s-0032-1317984  1
2013 Liu F, Paton RS, Kim S, Liang Y, Houk KN. Diels-Alder reactivities of strained and unstrained cycloalkenes with normal and inverse-electron-demand dienes: activation barriers and distortion/interaction analysis. Journal of the American Chemical Society. 135: 15642-9. PMID 24044412 DOI: 10.1021/ja408437u  1
2013 Sladojevich F, Fuentes de Arriba ÁL, Ortín I, Yang T, Ferrali A, Paton RS, Dixon DJ. Mechanistic investigations into the enantioselective Conia-ene reaction catalyzed by cinchona-derived amino urea pre-catalysts and Cu(I). Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 14286-95. PMID 24009075 DOI: 10.1002/chem.201200832  1
2013 Shepherd DJ, Broadwith PA, Dyson BS, Paton RS, Burton JW. Structure reassignment of laurefurenynes A and B by computation and total synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 12644-8. PMID 23963665 DOI: 10.1002/chem.201302349  1
2013 Lin YA, Boutureira O, Lercher L, Bhushan B, Paton RS, Davis BG. Rapid cross-metathesis for reversible protein modifications via chemical access to Se-allyl-selenocysteine in proteins. Journal of the American Chemical Society. 135: 12156-9. PMID 23889088 DOI: 10.1021/ja403191g  1
2013 Zou L, Paton RS, Eschenmoser A, Newhouse TR, Baran PS, Houk KN. Enhanced reactivity in dioxirane C-H oxidations via strain release: a computational and experimental study. The Journal of Organic Chemistry. 78: 4037-48. PMID 23461537 DOI: 10.1021/jo400350v  1
2013 Hodgson DM, Charlton A, Paton RS, Thompson AL. C-alkylation of chiral tropane- and homotropane-derived enamines. The Journal of Organic Chemistry. 78: 1508-18. PMID 23356473 DOI: 10.1021/jo3025972  1
2013 Jackson K, Jaffar SK, Paton RS. Computational organic chemistry Annual Reports On the Progress of Chemistry - Section B. 109: 235-255. DOI: 10.1039/c3oc90007j  1
2013 Chmely SC, Kim S, Ciesielski PN, Jiménez-Osés G, Paton RS, Beckham GT. Mechanistic study of a Ru-xantphos catalyst for tandem alcohol dehydrogenation and reductive aryl-ether cleavage Acs Catalysis. 3: 963-974. DOI: 10.1021/cs400110r  1
2012 Kim MJ, Sohn TI, Kim D, Paton RS. Concise substrate-controlled asymmetric total syntheses of dioxabicyclic marine natural products with 2,10-dioxabicyclo-[7.3.0]dodecene and 2,9-dioxabicyclo[6.3.0]undecene skeletons. Journal of the American Chemical Society. 134: 20178-88. PMID 23194584 DOI: 10.1021/ja310249u  1
2012 Paton RS, Brown JM. Dinuclear palladium complexes--precursors or catalysts? Angewandte Chemie (International Ed. in English). 51: 10448-50. PMID 22968902 DOI: 10.1002/anie.201205417  1
2012 Hotta K, Chen X, Paton RS, Minami A, Li H, Swaminathan K, Mathews II, Watanabe K, Oikawa H, Houk KN, Kim CY. Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis. Nature. 483: 355-8. PMID 22388816 DOI: 10.1038/nature10865  1
2012 Goetz AE, Bronner SM, Cisneros JD, Melamed JM, Paton RS, Houk KN, Garg NK. An efficient computational model to predict the synthetic utility of heterocyclic arynes. Angewandte Chemie (International Ed. in English). 51: 2758-62. PMID 22307724 DOI: 10.1002/anie.201108863  1
2011 Paton RS, Kim S, Ross AG, Danishefsky SJ, Houk KN. Experimental Diels-Alder reactivities of cycloalkenones and cyclic dienes explained through transition-state distortion energies. Angewandte Chemie (International Ed. in English). 50: 10366-8. PMID 21910195 DOI: 10.1002/anie.201103998  1
2011 Liu LP, Malhotra D, Jin Z, Paton RS, Houk KN, Hammond GB. Gold-catalyzed, intramolecular, oxygen-transfer reactions of 2-alkynyl-1,5-diketones or 2-alkynyl-5-ketoesters: scope, expansion, and mechanistic investigations on a new [4+2] cycloaddition. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 10690-9. PMID 21830243 DOI: 10.1002/chem.201101448  1
2011 Paton RS, Steinhardt SE, Vanderwal CD, Houk KN. Unraveling the mechanism of cascade reactions of zincke aldehydes. Journal of the American Chemical Society. 133: 3895-905. PMID 21351736 DOI: 10.1021/ja107988b  1
2011 Hodgson DM, Stent MAH, Paton RS, Wilson FX. Unusual base-induced rearrangement of exo-9-oxabicyclo[4.2.1]non-7-ene oxide to exo-8-hydroxybicyclo[3.3.0]octan-2-one Heterocycles. 84: 625-635. DOI: 10.3987/COM-11-S(P)35  1
2011 Kim S, Chmely SC, Nimlos MR, Bomble YJ, Foust TD, Paton RS, Beckham GT. Computational study of bond dissociation enthalpies for a large range of native and modified Lignins Journal of Physical Chemistry Letters. 2: 2846-2852. DOI: 10.1021/jz201182w  1
2011 Kim H, Bae H, Kim S, Kim D, Lee D, Paton RS. A stereoselective total synthesis of (±)-tormesol Tetrahedron. 67: 10017-10025. DOI: 10.1016/j.tet.2011.09.022  1
2011 Kiss G, Johnson SA, Nosrati G, Çelebi-Ölçüm N, Kim S, Paton R, Houk KN. Computational Design of New Protein Catalysts Modeling of Molecular Properties. 241-266. DOI: 10.1002/9783527636402.ch16  1
2010 Im GY, Bronner SM, Goetz AE, Paton RS, Cheong PH, Houk KN, Garg NK. Indolyne experimental and computational studies: synthetic applications and origins of selectivities of nucleophilic additions. Journal of the American Chemical Society. 132: 17933-44. PMID 21114321 DOI: 10.1021/ja1086485  1
2010 Liu LP, Malhotra D, Paton RS, Houk KN, Hammond GB. The [4+2], not [2+2], mechanism occurs in the gold-catalyzed intramolecular oxygen transfer reaction of 2-alkynyl-1,5-diketones. Angewandte Chemie (International Ed. in English). 49: 9132-5. PMID 21031394 DOI: 10.1002/anie.201005514  1
2010 Paton RS, Mackey JL, Kim WH, Lee JH, Danishefsky SJ, Houk KN. Origins of stereoselectivity in the trans Diels-Alder paradigm. Journal of the American Chemical Society. 132: 9335-40. PMID 20557046 DOI: 10.1021/ja1009162  1
2010 Cheong PH, Paton RS, Bronner SM, Im GY, Garg NK, Houk KN. Indolyne and aryne distortions and nucleophilic regioselectivites. Journal of the American Chemical Society. 132: 1267-9. PMID 20058924 DOI: 10.1021/ja9098643  1
2010 Hayden AE, Paton RS, Becker J, Lim YH, Nicolaou KC, Houk KN. Origins of regioselectivity of Diels-Alder reactions for the synthesis of bisanthraquinone antibiotic BE-43472B. The Journal of Organic Chemistry. 75: 922-8. PMID 20027998 DOI: 10.1021/jo902572y  1
2009 Paton RS, Maseras F. Gold(I)-catalyzed intermolecular hydroalkoxylation of allenes: a DFT study. Organic Letters. 11: 2237-40. PMID 19400580 DOI: 10.1021/ol9004646  1
2009 Paton RS, Goodman JM. Hydrogen bonding and pi-stacking: how reliable are force fields? A critical evaluation of force field descriptions of nonbonded interactions. Journal of Chemical Information and Modeling. 49: 944-55. PMID 19309094 DOI: 10.1021/ci900009f  1
2009 Paton RS, Goodman JM, Pellegrinet SC. Mechanistic insights into the catalytic asymmetric allylboration of ketones: Brønsted or Lewis acid activation? Organic Letters. 11: 37-40. PMID 19035769 DOI: 10.1021/ol802270u  1
2008 Paton RS, Goodman JM, Pellegrinet SC. Theoretical study of the asymmetric conjugate alkenylation of enones catalyzed by binaphthols. The Journal of Organic Chemistry. 73: 5078-89. PMID 18543992 DOI: 10.1021/jo8007463  1
2008 Smith SG, Paton RS, Burton JW, Goodman JM. Stereostructure assignment of flexible five-membered rings by GIAO 13C NMR calculations: prediction of the stereochemistry of elatenyne. The Journal of Organic Chemistry. 73: 4053-62. PMID 18471017 DOI: 10.1021/jo8003138  1
2008 Paton RS, Goodman JM. 1,5-anti stereocontrol in the boron-mediated aldol reactions of beta-alkoxy methyl ketones: the role of the formyl hydrogen bond. The Journal of Organic Chemistry. 73: 1253-63. PMID 18211083 DOI: 10.1021/jo701849x  1
2007 Paton RS, Goodman JM. Exploration of the accessible chemical space of acyclic alkanes. Journal of Chemical Information and Modeling. 47: 2124-32. PMID 17949070 DOI: 10.1021/ci700246b  1
2007 Goodman JM, Paton RS. Enantioselectivity in the boron aldol reactions of methyl ketones. Chemical Communications (Cambridge, England). 2124-6. PMID 17520110 DOI: 10.1039/b704786j  1
2006 Paton RS, Goodman JM. Understanding the origins of remote asymmetric induction in the boron aldol reactions of beta-alkoxy methyl ketones. Organic Letters. 8: 4299-302. PMID 16956211 DOI: 10.1021/ol061671q  1
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