Year |
Citation |
Score |
2018 |
Kedmi R, Veiga N, Ramishetti S, Goldsmith M, Rosenblum D, Dammes N, Hazan-Halevy I, Nahary L, Leviatan-Ben-Arye S, Harlev M, Behlke M, Benhar I, Lieberman J, Peer D. A modular platform for targeted RNAi therapeutics. Nature Nanotechnology. PMID 29379205 DOI: 10.1038/S41565-017-0043-5 |
0.349 |
|
2016 |
Halperin A, Shadkchan Y, Pisarevsky E, Szpilman AM, Sandovsky H, Osherov N, Benhar I. Novel Water-Soluble Amphotericin B-PEG Conjugates with Low Toxicity and Potent in Vivo Efficacy. Journal of Medicinal Chemistry. 59: 1197-206. PMID 26816333 DOI: 10.1021/Acs.Jmedchem.5B01862 |
0.345 |
|
2014 |
Mazor R, Eberle JA, Hu X, Vassall AN, Onda M, Beers R, Lee EC, Kreitman RJ, Lee B, Baker D, King C, Hassan R, Benhar I, Pastan I. Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes. Proceedings of the National Academy of Sciences of the United States of America. 111: 8571-6. PMID 24799704 DOI: 10.1073/Pnas.1405153111 |
0.442 |
|
2013 |
Mazor R, Vassall AN, Eberle JA, Beers R, Hu X, Benhar I, Pastan I. Abstract 4334: Identification and elimination of T-cell epitopes in recombinant immunotoxins used to treat cancer. Cancer Research. 73: 4334-4334. DOI: 10.1158/1538-7445.Am2013-4334 |
0.405 |
|
2012 |
Mazor R, Vassall AN, Eberle JA, Beers R, Weldon JE, Venzon DJ, Tsang KY, Benhar I, Pastan I. Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A. Proceedings of the National Academy of Sciences of the United States of America. 109: E3597-603. PMID 23213206 DOI: 10.1073/Pnas.1218138109 |
0.426 |
|
2012 |
Pichinuk E, Benhar I, Jacobi O, Chalik M, Weiss L, Ziv R, Sympson C, Karwa A, Smorodinsky NI, Rubinstein DB, Wreschner DH. Antibody targeting of cell-bound MUC1 SEA domain kills tumor cells. Cancer Research. 72: 3324-36. PMID 22507854 DOI: 10.1158/0008-5472.Can-12-0067 |
0.317 |
|
2012 |
Shapira A, Shapira S, Gal-Tanamy M, Zemel R, Tur-Kaspa R, Benhar I. Removal of hepatitis C virus-infected cells by a zymogenized bacterial toxin Plos One. 7. PMID 22359682 DOI: 10.1371/Journal.Pone.0032320 |
0.309 |
|
2010 |
Shapira A, Benhar I. Toxin-based therapeutic approaches Toxins. 2: 2519-2583. PMID 22069564 DOI: 10.3390/Toxins2112519 |
0.317 |
|
2009 |
Gal-Tanamy M, Zemel R, Bachmetov L, Jangra R, Villanueva R, Yi M, Lemon S, Benhar I, Tur-Kaspa R. 345 INHIBITION OF HCV CELL CULTURE INFECTIOUS VIRUS AND DRUG RESISTANT REPLICONS BY INTRABODIES Journal of Hepatology. 50: S132-S133. DOI: 10.1016/S0168-8278(09)60347-0 |
0.301 |
|
2008 |
Yacoby I, Benhar I. Antibacterial nanomedicine. Nanomedicine (London, England). 3: 329-41. PMID 18510428 DOI: 10.2217/17435889.3.3.329 |
0.652 |
|
2008 |
Bar H, Yacoby I, Benhar I. Killing cancer cells by targeted drug-carrying phage nanomedicines. Bmc Biotechnology. 8: 37-37. PMID 18387177 DOI: 10.1186/1472-6750-8-37 |
0.694 |
|
2008 |
Yacoby I, Benhar I. Targeted filamentous bacteriophages as therapeutic agents Expert Opinion On Drug Delivery. 5: 321-329. PMID 18318653 DOI: 10.1517/17425247.5.3.321 |
0.7 |
|
2008 |
Trahtenherts A, Gal-Tanamy M, Zemel R, Bachmatov L, Loewenstein S, Tur-Kaspa R, Benhar I. Inhibition of hepatitis C virus RNA replicons by peptide aptamers. Antiviral Research. 77: 195-205. PMID 18243349 DOI: 10.1016/J.Antiviral.2007.12.013 |
0.308 |
|
2007 |
Yacoby I, Benhar I. Targeted anti bacterial therapy. Infectious Disorders Drug Targets. 7: 221-229. PMID 17897058 DOI: 10.2174/187152607782109998 |
0.702 |
|
2007 |
Yacoby I, Bar H, Benhar I. Targeted drug-carrying bacteriophages as antibacterial nanomedicines. Antimicrobial Agents and Chemotherapy. 51: 2156-2163. PMID 17404004 DOI: 10.1128/Aac.00163-07 |
0.704 |
|
2006 |
Rubinstein DB, Karmely M, Ziv R, Benhar I, Leitner O, Baron S, Katz BZ, Wreschner DH. MUC1/X protein immunization enhances cDNA immunization in generating anti-MUC1 alpha/beta junction antibodies that target malignant cells. Cancer Research. 66: 11247-53. PMID 17145869 DOI: 10.1158/0008-5472.Can-06-1486 |
0.304 |
|
2006 |
Yacoby I, Shamis M, Bar H, Shabat D, Benhar I. Targeting antibacterial agents by using drug-carrying filamentous bacteriophages. Antimicrobial Agents and Chemotherapy. 50: 2087-97. PMID 16723570 DOI: 10.1128/Aac.00169-06 |
0.706 |
|
2005 |
Gal-Tanamy M, Zemel R, Berdichevsky Y, Bachmatov L, Tur-Kaspa R, Benhar I. HCV NS3 serine protease-neutralizing single-chain antibodies isolated by a novel genetic screen. Journal of Molecular Biology. 347: 991-1003. PMID 15784258 DOI: 10.1016/J.Jmb.2005.02.020 |
0.318 |
|
2004 |
Zemel R, Berdichevsky Y, Bachmatov L, Benhar I, Tur-Kaspa R. Inhibition of hepatitis C virus NS3-mediated cell transformation by recombinant intracellular antibodies. Journal of Hepatology. 40: 1000-7. PMID 15158342 DOI: 10.1016/J.Jhep.2004.02.026 |
0.308 |
|
2004 |
Azriel-Rosenfeld R, Valensi M, Benhar I. A human synthetic combinatorial library of arrayable single-chain antibodies based on shuffling in vivo formed CDRs into general framework regions. Journal of Molecular Biology. 335: 177-92. PMID 14659749 DOI: 10.1016/J.Jmb.2003.10.053 |
0.315 |
|
2003 |
Denkberg G, Lev A, Eisenbach L, Benhar I, Reiter Y. Selective targeting of melanoma and APCs using a recombinant antibody with TCR-like specificity directed toward a melanoma differentiation antigen. Journal of Immunology (Baltimore, Md. : 1950). 171: 2197-207. PMID 12928363 DOI: 10.4049/Jimmunol.171.5.2197 |
0.318 |
|
2002 |
Mazor Y, Gilead S, Benhar I, Gazit E. Identification and characterization of a novel molecular-recognition and self-assembly domain within the islet amyloid polypeptide. Journal of Molecular Biology. 322: 1013-24. PMID 12367525 DOI: 10.1016/S0022-2836(02)00887-2 |
0.464 |
|
1998 |
Almog O, Benhar I, Vasmatzis G, Tordova M, Lee B, Pastan I, Gilliland GL. Crystal structure of the disulfide-stabilized Fv fragment of anticancer antibody B1: conformational influence of an engineered disulfide bond. Proteins. 31: 128-38. PMID 9593187 DOI: 10.1002/(Sici)1097-0134(19980501)31:2<128::Aid-Prot3>3.0.Co;2-I |
0.413 |
|
1996 |
Li M, Dyda F, Benhar I, Pastan I, Davies DR. Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation. Proceedings of the National Academy of Sciences of the United States of America. 93: 6902-6. PMID 8692916 DOI: 10.1073/Pnas.93.14.6902 |
0.405 |
|
1995 |
Benhar I, Padlan EA, Jung SH, Lee B, Pastan I. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38. Proceedings of the National Academy of Sciences of the United States of America. 91: 12051-5. PMID 7991583 DOI: 10.1073/Pnas.91.25.12051 |
0.41 |
|
1995 |
Benhar I, Pastan I. Cloning, expression and characterization of the Fv fragments of the anti-carbohydrate mAbs B1 and B5 as single-chain immunotoxins. Protein Engineering. 7: 1509-15. PMID 7716163 DOI: 10.1093/Protein/7.12.1509 |
0.405 |
|
1995 |
Benhar I, Reiter Y, Pai LH, Pastan I. Administration of disulfide-stabilized Fv-immunotoxins B1(dsFv)-PE38 and B3(dsFv)-PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice. International Journal of Cancer. 62: 351-5. PMID 7628878 DOI: 10.1002/Ijc.2910620320 |
0.405 |
|
1995 |
Li M, Dyda F, Benhar I, Pastan I, Davies DR. The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin. Proceedings of the National Academy of Sciences of the United States of America. 92: 9308-12. PMID 7568123 DOI: 10.1073/Pnas.92.20.9308 |
0.405 |
|
1995 |
Benhar I, Pastan I. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3. The Journal of Biological Chemistry. 270: 23373-80. PMID 7559495 DOI: 10.1074/Jbc.270.40.23373 |
0.405 |
|
1994 |
Benhar I, Brinkmann U, Webber KO, Pastan I. Mutations of two lysine residues in the CDR loops of a recombinant immunotoxin that reduce its sensitivity to chemical derivatization. Bioconjugate Chemistry. 5: 321-326. PMID 7948099 DOI: 10.1021/Bc00028A007 |
0.405 |
|
1994 |
Roscoe DM, Jung SH, Benhar I, Pai L, Lee BK, Pastan I. Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin. Infection and Immunity. 62: 5055-65. PMID 7927788 DOI: 10.1128/Iai.62.11.5055-5065.1994 |
0.405 |
|
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