Itai Benhar - Publications

Affiliations: 
Tel Aviv University, Tel Aviv-Yafo, Tel Aviv District, Israel 

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kedmi R, Veiga N, Ramishetti S, Goldsmith M, Rosenblum D, Dammes N, Hazan-Halevy I, Nahary L, Leviatan-Ben-Arye S, Harlev M, Behlke M, Benhar I, Lieberman J, Peer D. A modular platform for targeted RNAi therapeutics. Nature Nanotechnology. PMID 29379205 DOI: 10.1038/S41565-017-0043-5  0.349
2016 Halperin A, Shadkchan Y, Pisarevsky E, Szpilman AM, Sandovsky H, Osherov N, Benhar I. Novel Water-Soluble Amphotericin B-PEG Conjugates with Low Toxicity and Potent in Vivo Efficacy. Journal of Medicinal Chemistry. 59: 1197-206. PMID 26816333 DOI: 10.1021/Acs.Jmedchem.5B01862  0.345
2014 Mazor R, Eberle JA, Hu X, Vassall AN, Onda M, Beers R, Lee EC, Kreitman RJ, Lee B, Baker D, King C, Hassan R, Benhar I, Pastan I. Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes. Proceedings of the National Academy of Sciences of the United States of America. 111: 8571-6. PMID 24799704 DOI: 10.1073/Pnas.1405153111  0.442
2013 Mazor R, Vassall AN, Eberle JA, Beers R, Hu X, Benhar I, Pastan I. Abstract 4334: Identification and elimination of T-cell epitopes in recombinant immunotoxins used to treat cancer. Cancer Research. 73: 4334-4334. DOI: 10.1158/1538-7445.Am2013-4334  0.405
2012 Mazor R, Vassall AN, Eberle JA, Beers R, Weldon JE, Venzon DJ, Tsang KY, Benhar I, Pastan I. Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A. Proceedings of the National Academy of Sciences of the United States of America. 109: E3597-603. PMID 23213206 DOI: 10.1073/Pnas.1218138109  0.426
2012 Pichinuk E, Benhar I, Jacobi O, Chalik M, Weiss L, Ziv R, Sympson C, Karwa A, Smorodinsky NI, Rubinstein DB, Wreschner DH. Antibody targeting of cell-bound MUC1 SEA domain kills tumor cells. Cancer Research. 72: 3324-36. PMID 22507854 DOI: 10.1158/0008-5472.Can-12-0067  0.317
2012 Shapira A, Shapira S, Gal-Tanamy M, Zemel R, Tur-Kaspa R, Benhar I. Removal of hepatitis C virus-infected cells by a zymogenized bacterial toxin Plos One. 7. PMID 22359682 DOI: 10.1371/Journal.Pone.0032320  0.309
2010 Shapira A, Benhar I. Toxin-based therapeutic approaches Toxins. 2: 2519-2583. PMID 22069564 DOI: 10.3390/Toxins2112519  0.317
2009 Gal-Tanamy M, Zemel R, Bachmetov L, Jangra R, Villanueva R, Yi M, Lemon S, Benhar I, Tur-Kaspa R. 345 INHIBITION OF HCV CELL CULTURE INFECTIOUS VIRUS AND DRUG RESISTANT REPLICONS BY INTRABODIES Journal of Hepatology. 50: S132-S133. DOI: 10.1016/S0168-8278(09)60347-0  0.301
2008 Yacoby I, Benhar I. Antibacterial nanomedicine. Nanomedicine (London, England). 3: 329-41. PMID 18510428 DOI: 10.2217/17435889.3.3.329  0.652
2008 Bar H, Yacoby I, Benhar I. Killing cancer cells by targeted drug-carrying phage nanomedicines. Bmc Biotechnology. 8: 37-37. PMID 18387177 DOI: 10.1186/1472-6750-8-37  0.694
2008 Yacoby I, Benhar I. Targeted filamentous bacteriophages as therapeutic agents Expert Opinion On Drug Delivery. 5: 321-329. PMID 18318653 DOI: 10.1517/17425247.5.3.321  0.7
2008 Trahtenherts A, Gal-Tanamy M, Zemel R, Bachmatov L, Loewenstein S, Tur-Kaspa R, Benhar I. Inhibition of hepatitis C virus RNA replicons by peptide aptamers. Antiviral Research. 77: 195-205. PMID 18243349 DOI: 10.1016/J.Antiviral.2007.12.013  0.308
2007 Yacoby I, Benhar I. Targeted anti bacterial therapy. Infectious Disorders Drug Targets. 7: 221-229. PMID 17897058 DOI: 10.2174/187152607782109998  0.702
2007 Yacoby I, Bar H, Benhar I. Targeted drug-carrying bacteriophages as antibacterial nanomedicines. Antimicrobial Agents and Chemotherapy. 51: 2156-2163. PMID 17404004 DOI: 10.1128/Aac.00163-07  0.704
2006 Rubinstein DB, Karmely M, Ziv R, Benhar I, Leitner O, Baron S, Katz BZ, Wreschner DH. MUC1/X protein immunization enhances cDNA immunization in generating anti-MUC1 alpha/beta junction antibodies that target malignant cells. Cancer Research. 66: 11247-53. PMID 17145869 DOI: 10.1158/0008-5472.Can-06-1486  0.304
2006 Yacoby I, Shamis M, Bar H, Shabat D, Benhar I. Targeting antibacterial agents by using drug-carrying filamentous bacteriophages. Antimicrobial Agents and Chemotherapy. 50: 2087-97. PMID 16723570 DOI: 10.1128/Aac.00169-06  0.706
2005 Gal-Tanamy M, Zemel R, Berdichevsky Y, Bachmatov L, Tur-Kaspa R, Benhar I. HCV NS3 serine protease-neutralizing single-chain antibodies isolated by a novel genetic screen. Journal of Molecular Biology. 347: 991-1003. PMID 15784258 DOI: 10.1016/J.Jmb.2005.02.020  0.318
2004 Zemel R, Berdichevsky Y, Bachmatov L, Benhar I, Tur-Kaspa R. Inhibition of hepatitis C virus NS3-mediated cell transformation by recombinant intracellular antibodies. Journal of Hepatology. 40: 1000-7. PMID 15158342 DOI: 10.1016/J.Jhep.2004.02.026  0.308
2004 Azriel-Rosenfeld R, Valensi M, Benhar I. A human synthetic combinatorial library of arrayable single-chain antibodies based on shuffling in vivo formed CDRs into general framework regions. Journal of Molecular Biology. 335: 177-92. PMID 14659749 DOI: 10.1016/J.Jmb.2003.10.053  0.315
2003 Denkberg G, Lev A, Eisenbach L, Benhar I, Reiter Y. Selective targeting of melanoma and APCs using a recombinant antibody with TCR-like specificity directed toward a melanoma differentiation antigen. Journal of Immunology (Baltimore, Md. : 1950). 171: 2197-207. PMID 12928363 DOI: 10.4049/Jimmunol.171.5.2197  0.318
2002 Mazor Y, Gilead S, Benhar I, Gazit E. Identification and characterization of a novel molecular-recognition and self-assembly domain within the islet amyloid polypeptide. Journal of Molecular Biology. 322: 1013-24. PMID 12367525 DOI: 10.1016/S0022-2836(02)00887-2  0.464
1998 Almog O, Benhar I, Vasmatzis G, Tordova M, Lee B, Pastan I, Gilliland GL. Crystal structure of the disulfide-stabilized Fv fragment of anticancer antibody B1: conformational influence of an engineered disulfide bond. Proteins. 31: 128-38. PMID 9593187 DOI: 10.1002/(Sici)1097-0134(19980501)31:2<128::Aid-Prot3>3.0.Co;2-I  0.413
1996 Li M, Dyda F, Benhar I, Pastan I, Davies DR. Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation. Proceedings of the National Academy of Sciences of the United States of America. 93: 6902-6. PMID 8692916 DOI: 10.1073/Pnas.93.14.6902  0.405
1995 Benhar I, Padlan EA, Jung SH, Lee B, Pastan I. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38. Proceedings of the National Academy of Sciences of the United States of America. 91: 12051-5. PMID 7991583 DOI: 10.1073/Pnas.91.25.12051  0.41
1995 Benhar I, Pastan I. Cloning, expression and characterization of the Fv fragments of the anti-carbohydrate mAbs B1 and B5 as single-chain immunotoxins. Protein Engineering. 7: 1509-15. PMID 7716163 DOI: 10.1093/Protein/7.12.1509  0.405
1995 Benhar I, Reiter Y, Pai LH, Pastan I. Administration of disulfide-stabilized Fv-immunotoxins B1(dsFv)-PE38 and B3(dsFv)-PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice. International Journal of Cancer. 62: 351-5. PMID 7628878 DOI: 10.1002/Ijc.2910620320  0.405
1995 Li M, Dyda F, Benhar I, Pastan I, Davies DR. The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin. Proceedings of the National Academy of Sciences of the United States of America. 92: 9308-12. PMID 7568123 DOI: 10.1073/Pnas.92.20.9308  0.405
1995 Benhar I, Pastan I. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3. The Journal of Biological Chemistry. 270: 23373-80. PMID 7559495 DOI: 10.1074/Jbc.270.40.23373  0.405
1994 Benhar I, Brinkmann U, Webber KO, Pastan I. Mutations of two lysine residues in the CDR loops of a recombinant immunotoxin that reduce its sensitivity to chemical derivatization. Bioconjugate Chemistry. 5: 321-326. PMID 7948099 DOI: 10.1021/Bc00028A007  0.405
1994 Roscoe DM, Jung SH, Benhar I, Pai L, Lee BK, Pastan I. Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin. Infection and Immunity. 62: 5055-65. PMID 7927788 DOI: 10.1128/Iai.62.11.5055-5065.1994  0.405
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