| Year |
Citation |
Score |
| 2010 |
Chou YC, Chung YT, Liu TY, Wang SY, Chau GY, Chi CW, Souček P, Krausz KW, Gelboin HV, Lee CH, Ueng YF. The oxidative metabolism of dimemorfan by human cytochrome p450 enzymes Journal of Pharmaceutical Sciences. 99: 1063-1077. PMID 19593786 DOI: 10.1002/Jps.21866 |
0.309 |
|
| 2007 |
Elovaara E, Stockmann-Juvala H, Mikkola J, Gelboin HV. Interactive effects of methyl tertiary-butyl ether (MTBE) and tertiary-amyl methyl ether (TAME), ethanol and some drugs: Triglyceridemia, liver toxicity and induction of CYP (2E1, 2B1) and phase II enzymes in female Wistar rats. Environmental Toxicology and Pharmacology. 23: 64-72. PMID 21783738 DOI: 10.1016/J.Etap.2006.07.003 |
0.418 |
|
| 2006 |
Gelboin HV, Krausz K. Monoclonal antibodies and multifunctional cytochrome P450: Drug metabolism as paradigm Journal of Clinical Pharmacology. 46: 353-372. PMID 16490812 DOI: 10.1177/0091270005285200 |
0.379 |
|
| 2005 |
Aleksa K, Matsell D, Krausz K, Gelboin H, Ito S, Koren G. Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity. Pediatric Nephrology (Berlin, Germany). 20: 872-85. PMID 15875221 DOI: 10.1007/S00467-004-1807-3 |
0.325 |
|
| 2004 |
Ufer M, Svensson JO, Krausz KW, Gelboin HV, Rane A, Tybring G. Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro European Journal of Clinical Pharmacology. 60: 173-182. PMID 15054565 DOI: 10.1007/S00228-004-0740-5 |
0.388 |
|
| 2004 |
Hu Y, Krausz K, Gelboin HV, Kupfer D. CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: Use of inhibitory monoclonal antibodies in P450 identification Xenobiotica. 34: 117-132. PMID 14985143 DOI: 10.1080/00498250310001644535 |
0.305 |
|
| 2002 |
Granvil CP, Krausz KW, Gelboin HV, Idle JR, Gonzalez FJ. 4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine Journal of Pharmacology and Experimental Therapeutics. 301: 1025-1032. PMID 12023534 DOI: 10.1124/Jpet.301.3.1025 |
0.413 |
|
| 2001 |
Friedman FK, Park SS, Fujino T, Song BJ, Robinson RC, West D, Radkowsky AK, Miller H, Gelboin HV. Phenotyping cytochromes P450 with monoclonal antibodies. Toxicologic Pathology. 12: 155-61. PMID 11478317 DOI: 10.1177/019262338401200207 |
0.428 |
|
| 2000 |
Niemelä O, Parkkila S, Juvonen RO, Viitala K, Gelboin HV, Pasanen M. Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases Journal of Hepatology. 33: 893-901. PMID 11131450 DOI: 10.1016/S0168-8278(00)80120-8 |
0.345 |
|
| 2000 |
Krausz KW, Goldfarb I, Yang TJ, Gonzalez FJ, Gelboin HV. An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys Xenobiotica. 30: 619-625. PMID 10923863 DOI: 10.1080/004982500406444 |
0.373 |
|
| 2000 |
Sai Y, Dai R, Yang TJ, Krausz KW, Gonzalez FJ, Gelboin HV, Shou M. Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450 Xenobiotica. 30: 327-343. PMID 10821163 DOI: 10.1080/004982500237541 |
0.379 |
|
| 2000 |
Shou M, Lu T, Krausz KW, Sai Y, Yang T, Korzekwa KR, Gonzalez FJ, Gelboin HV. Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism European Journal of Pharmacology. 394: 199-209. PMID 10771285 DOI: 10.1016/S0014-2999(00)00079-0 |
0.454 |
|
| 1999 |
Gelboin HV, Krausz KW, Gonzalez FJ, Yang TJ. Inhibitory monoclonal antibodies to human cytochrome P450 enzymes: A new avenue for drug discovery Trends in Pharmacological Sciences. 20: 432-438. PMID 10542439 DOI: 10.1016/S0165-6147(99)01382-6 |
0.371 |
|
| 1999 |
Miyata M, Kudo G, Lee YH, Yang TJ, Gelboin HV, Fernandez-Salguero P, Kimura S, Gonzalez FJ. Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12- dimethylbenz[a]anthracene Journal of Biological Chemistry. 274: 23963-23968. PMID 10446164 DOI: 10.1074/Jbc.274.34.23963 |
0.318 |
|
| 1999 |
Sai Y, Jian Yang T, Krausz KW, Gonzalez FJ, Gelboin HV. An inhibitory monoclonal antibody to human cytochrome P450 2A6 defines its role in the metabolism of coumarin, 7-ethoxycoumarin and 4-nitroanisole in human liver Pharmacogenetics. 9: 229-237. PMID 10376770 |
0.31 |
|
| 1999 |
Chen SC, Wang X, Xu G, Zhou L, Vennerstrom JL, Gonzalez F, Gelboin HV, Mirvish SS. Depentylation of [3H-pentyl]methyl-n-amylnitrosamine by rat esophageal and liver microsomes and by rat and human cytochrome P450 isoforms Cancer Research. 59: 91-98. PMID 9892192 |
0.354 |
|
| 1999 |
Cai Y, Marcus C, Guengerich FP, Gelboin HV, Baird WM. Roles of cytochrome P450 1a1 and 1b1 in metabolic activation of dibenzo[a,l]pyrene by microsomes from the human mammary carcinoma cell line MCF-7 Polycyclic Aromatic Compounds. 16: 109-118. DOI: 10.1080/10406639908020578 |
0.402 |
|
| 1998 |
Gelboin HV, Shou M, Goldfarb I, Yang TJ, Krausz K. Monoclonal antibodies to cytochromes P450. Methods in Molecular Biology (Clifton, N.J.). 107: 227-237. PMID 14577233 DOI: 10.1385/0-89603-519-0:227 |
0.356 |
|
| 1998 |
Shou M, Martinet M, Korzekwa KR, Krausz KW, Gonzalez FJ, Gelboin HV. Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: Enzyme specificity, interindividual distribution and metabolic contribution in human liver Pharmacogenetics. 8: 391-401. PMID 9825831 DOI: 10.1097/00008571-199810000-00004 |
0.417 |
|
| 1998 |
Yang TJ, Sai Y, Krausz KW, Gonzalez FJ, Gelboin HV. Inhibitory monoclonal antibodies to human cytochrome P450 1A2: Analysis of phenacetin O-deethylation in human liver Pharmacogenetics. 8: 375-382. PMID 9825829 DOI: 10.1097/00008571-199810000-00002 |
0.37 |
|
| 1998 |
Yang TJ, Krausz KW, Shou M, Yang SK, Buters JTM, Gonzalez FJ, Gelboin HV. Inhibitory monoclonal antibody to human cytochrome P450 2B6 Biochemical Pharmacology. 55: 1633-1640. PMID 9633999 DOI: 10.1016/S0006-2952(98)00018-5 |
0.413 |
|
| 1998 |
Yang TJ, Shou M, Korzekwa KR, Gonzalez FJ, Gelboin HV, Yang SK. Role of cDNA-expressed human cytochromes P450 in the metabolism of diazepam Biochemical Pharmacology. 55: 889-896. PMID 9586962 DOI: 10.1016/S0006-2952(97)00558-3 |
0.354 |
|
| 1998 |
Zaher H, Yang TJ, Gelboin HV, Fernandez-Salguero P, Gonzalez FJ. Effect of phenobarbital on hepatic CYP1A1 and CYP1A2 in the Ahr-null mouse Biochemical Pharmacology. 55: 235-238. PMID 9448747 DOI: 10.1016/S0006-2952(97)00476-0 |
0.32 |
|
| 1997 |
Gelboin HV, Krausz KW, Shou M, Gonzalez FJ, Yang TJ. A monoclonal antibody inhibitory to human P450 2D6: A paradigm for use in combinatorial determination of individual P450 role in specific drug tissue metabolism Pharmacogenetics. 7: 469-477. PMID 9429232 DOI: 10.1097/00008571-199712000-00005 |
0.435 |
|
| 1997 |
Krausz KW, Yang TJ, Gonzalez FJ, Shou M, Gelboin HV. Inhibitory monoclonal antibodies to human cytochrome P450 2D6 Biochemical Pharmacology. 54: 15-17. PMID 9296346 DOI: 10.1016/S0006-2952(97)00261-X |
0.349 |
|
| 1997 |
Nakajima T, Wang RS, Elovaara E, Gonzalez FJ, Gelboin HV, Raunio H, Pelkonen O, Vainio H, Aoyama T. Toluene metabolism by cDNA-expressed human hepatic cytochrome P450 Biochemical Pharmacology. 53: 271-277. PMID 9065730 DOI: 10.1016/S0006-2952(96)00652-1 |
0.444 |
|
| 1997 |
Shou M, Korzekwa KR, Brooks EN, Krausz KW, Gonzalez FJ, Gelboin HV. Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone Carcinogenesis. 18: 207-214. PMID 9054608 DOI: 10.1093/Carcin/18.1.207 |
0.346 |
|
| 1996 |
Gut I, Nedelcheva V, Souček P, Stopka P, Vodička P, Gelboin HV, Ingelman-Sundberg M. The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives Archives of Toxicology. 71: 45-56. PMID 9010585 DOI: 10.1007/S002040050357 |
0.338 |
|
| 1996 |
Shou M, Korzekwa KR, Krausz KW, Buters JTM, Grogan J, Goldfarb I, Hardwick JP, Gonzalez FJ, Gelboin HV. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene Molecular Carcinogenesis. 17: 241-249. PMID 8989918 DOI: 10.1002/(Sici)1098-2744(199612)17:4<241::Aid-Mc8>3.0.Co;2-G |
0.453 |
|
| 1996 |
Shou M, Krausz KW, Gonzalez FJ, Gelboin HV. Metabolic activation of the potent carcinogen dibenzo[a,l]pyrene by human recombinant cytochromes P450, lung and liver microsomes Carcinogenesis. 17: 2429-2433. PMID 8968059 DOI: 10.1093/Carcin/17.11.2429 |
0.43 |
|
| 1996 |
Buters JTM, Tang BK, Pineau T, Gelboin HV, Kimura S, Gonzalez FJ. Role of CYP1A2 in caffeine pharmacokinetics and metabolism: Studies using mice deficient in CYP1A2 Pharmacogenetics. 6: 291-296. PMID 8873215 DOI: 10.1097/00008571-199608000-00002 |
0.32 |
|
| 1996 |
Gelboin HV, Goldfarb I, Krausz KW, Grogan J, Korzekwa KR, Gonzalez FJ, Shou M. Inhibitory and noninhibitory monoclonal antibodies to human cytochrome P450 2E1 Chemical Research in Toxicology. 9: 1023-1030. PMID 8870991 DOI: 10.1021/Tx9600154 |
0.465 |
|
| 1996 |
Kraul H, Pasanen M, Sigusch H, Stenbäck F, Park SS, Gelboin HV, Pelkonen O. Immunohistochemical properties of dipyrone-induced cytochromes P450 in rats Human and Experimental Toxicology. 15: 45-50. PMID 8845208 |
0.345 |
|
| 1996 |
Shou M, Krausz KW, Gonzalez FJ, Gelboin HV. Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450 Archives of Biochemistry and Biophysics. 328: 201-207. PMID 8638931 DOI: 10.1006/Abbi.1996.0161 |
0.39 |
|
| 1996 |
Omar RF, Gelboin HV, Rahimtula AD. Effect of cytochrome P450 induction on the metabolism and toxicity of ochratoxin A Biochemical Pharmacology. 51: 207-216. PMID 8573185 DOI: 10.1016/0006-2952(95)02194-9 |
0.405 |
|
| 1995 |
Gelboin HV, Krausz KW, Goldfarb I, Buters JTM, Yang SK, Gonzalez FJ, Korzekwa KR, Shou M. Inhibitory and non-inhibitory monoclonal antibodies to human cytochrome P450 3A3/4 Biochemical Pharmacology. 50: 1841-1850. PMID 8615863 DOI: 10.1016/0006-2952(95)02077-2 |
0.322 |
|
| 1995 |
Crespi CL, Steimel DT, Penman BW, Korzekwa KR, Fernandez-Salguero P, Buters JTM, Gelboin HV, Gonzalez FJ, Idle JR, Daly AK. Comparison of substrate metabolism by wild type CYP2D6 protein and a variant containing methionine, not valine, at position 374 Pharmacogenetics. 5: 234-243. PMID 8528270 DOI: 10.1097/00008571-199508000-00007 |
0.345 |
|
| 1995 |
Mirvish SS, Huang Q, Williamson J, Chen SC, Gelboin HV. Use of monoclonal antibodies to cytochrome P450s to indicate the critical dealkylation and the P450s involved in methyl-n-amylnitrosamine mutagenicity in the presence of induced rat liver microsomes Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 331: 161-170. PMID 7666863 DOI: 10.1016/0027-5107(95)00065-Q |
0.413 |
|
| 1995 |
Nakajima T, Elovaara E, Okino T, Gelboin HV, Klockars M, Riihimaki V, Aoyama T, Vainio H. Different contributions of cytochrome P450 2E1 and P450 2B1/2 to chloroform hepatotoxicity in rat Toxicology and Applied Pharmacology. 133: 215-222. PMID 7645016 DOI: 10.1006/Taap.1995.1144 |
0.367 |
|
| 1994 |
Shou M, Grogan J, Mancewicz JA, Krausz KW, Gonzalez FJ, Gelboin HV, Korzekwa KR. Activation of CYP3A4: Evidence for the simultaneous binding of two substrates in a cytochrome P450 active site Biochemistry®. 6450-6455. PMID 8204577 DOI: 10.1021/Bi00187A009 |
0.382 |
|
| 1994 |
Thirman MJ, Albrecht JH, Krueger MA, Erickson RR, Cherwitz DL, Park SS, Gelboin HV, Holtzman JL. Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: A possible role in atherogenesis Proceedings of the National Academy of Sciences of the United States of America. 91: 5397-5401. PMID 8202497 DOI: 10.1073/Pnas.91.12.5397 |
0.312 |
|
| 1994 |
Tsyrlov IB, Mikhailenko VM, Gelboin HV. Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1205: 325-335. PMID 8155716 DOI: 10.1016/0167-4838(94)90252-6 |
0.445 |
|
| 1994 |
Gonzalez FJ, Gelboin HV. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins Drug Metabolism Reviews. 26: 165-183. PMID 8082563 DOI: 10.3109/03602539409029789 |
0.408 |
|
| 1994 |
Tamie N, Rui-Sheng W, Elovaara E, Gonzalez FJ, Gelboin HV, Vainio H, Toshifumi A. CYP2C11 and CYP2B1 are major cytochrome P450 forms involved in styrene oxidation in liver and lung microsomes from untreated rats, respectively Biochemical Pharmacology. 48: 637-642. PMID 8080435 DOI: 10.1016/0006-2952(94)90039-6 |
0.461 |
|
| 1994 |
Shou M, Korzekwa KR, Krausz KW, Crespi CL, Gonzalez FJ, Gelboin HV. Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA-expressed human, rodent, and rabbit cytochromes P-450 Cancer Letters. 83: 305-313. PMID 8062229 DOI: 10.1016/0304-3835(94)90334-4 |
0.442 |
|
| 1994 |
Shou M, Korzekwa KR, Crespi CL, Gonzalez FJ, Gelboin HV. The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol Molecular Carcinogenesis. 10: 159-168. PMID 8043197 DOI: 10.1002/Mc.2940100307 |
0.429 |
|
| 1994 |
Omata Y, Robinson RC, Gelboin HV, Pincus MR, Friedman FK. Specificity of the cytochrome P-450 interaction with cytochrome b5 Febs Letters. 346: 241-245. PMID 8013641 DOI: 10.1016/0014-5793(94)00482-X |
0.391 |
|
| 1994 |
Chaloupka K, Santostefano M, Goldfarb IS, Liu G, Myers MJ, Tsyrolv IB, Gelboin HV, Krishnan V, Safe S. Aryl hydrocarbon (Ah) receptor-independent induction of Cyp1a2 gene expression by acenaphthylene and related compounds in B6C3F1 mice Carcinogenesis. 15: 2835-2840. PMID 8001243 DOI: 10.1093/Carcin/15.12.2835 |
0.397 |
|
| 1994 |
Penman BW, Chen L, Gelboin HV, Gonzalez FJ, Crespi CL. Development of a human lymphoblastoid cell line constitutively expressing human CYP1A1 cDNA: Substrate specificity with model substrates and promutagens Carcinogenesis. 15: 1931-1937. PMID 7923587 DOI: 10.1093/Carcin/15.9.1931 |
0.349 |
|
| 1994 |
Nakajima T, Elovaara E, Gonzalez FJ, Gelboin HV, Raunio H, Pelkonen O, Vainio H, Aoyama T. Styrene metabolism by cDNA-expressed human hepatic and pulmonary cytochromes P450 Chemical Research in Toxicology. 7: 891-896. PMID 7696548 DOI: 10.1021/Tx00042A026 |
0.443 |
|
| 1993 |
Huang Q, Wang S, Chen SC, Babcook DM, Park SS, Gelboin HV, Mirvish SS. Hydroxylation and dealkylation of methyl-n-butylnitrosamine and role of certain cytochrome P-450 isozymes in these reactions Cancer Letters. 69: 107-116. PMID 8495399 DOI: 10.1016/0304-3835(93)90162-3 |
0.387 |
|
| 1993 |
Penman BW, Reece J, Smith T, Yang CS, Gelboin HV, Gonzalez FJ, Crespi CL. Characterization of a human cell line expressing high levels of cDNA-derived CYP2D6 Pharmacogenetics. 3: 28-39. PMID 8485585 DOI: 10.1097/00008571-199302000-00003 |
0.399 |
|
| 1993 |
Tamie N, Rui-Sheng W, Elovaara E, Park SS, Gelboin HV, Vainio H. Cytochrome P450-related differences between rats and mice in the metabolism of benzene, toluene and trichloroethylene in liver microsomes Biochemical Pharmacology. 45: 1079-1085. PMID 8461037 DOI: 10.1016/0006-2952(93)90252-R |
0.41 |
|
| 1993 |
Goldfarb I, Korzekwa K, Krausz KW, Gonzalez F, Gelboin HV. Cross-reactivity of thirteen monoclonal antibodies with ten vaccinia cDNA expressed rat, mouse and human cytochrome P450s Biochemical Pharmacology. 46: 787-790. PMID 8373431 DOI: 10.1016/0006-2952(93)90485-F |
0.392 |
|
| 1993 |
Wang RS, Nakajima T, Park SS, Gelboin HV, Murayama N. Monoclonal antibody-directed assessment of toluene induction of rat hepatic cytochrome P450 isozymes. Biochemical Pharmacology. 46: 413-9. PMID 8347164 |
0.305 |
|
| 1993 |
Tsyrlov IB, Goldfarb IS, Gelboin HV. Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2 Archives of Biochemistry and Biophysics. 307: 259-266. PMID 8274012 DOI: 10.1006/Abbi.1993.1588 |
0.416 |
|
| 1993 |
Gonzalez FJ, Gelboin HV. Role of human cytochrome P-450s in risk assessment and susceptibility to environmentally based disease Journal of Toxicology and Environmental Health. 40: 289-308. PMID 8230303 DOI: 10.1080/15287399309531795 |
0.422 |
|
| 1993 |
Bjelogrlic N, Peng R, Park SS, Gelboin HV, Honkakoski P, Pelkonen O, Vahakangas K. Involvement of P450 1A1 in benzo(a)pyrene but not in benzo(a)pyrene-7,8-dihydrodiol activation by 3-methylcholanthrene-induced mouse liver microsomes Pharmacology and Toxicology. 73: 319-324. PMID 8153055 DOI: 10.1111/J.1600-0773.1993.Tb01359.X |
0.412 |
|
| 1993 |
Crespi CL, Penman BW, Gonzalez FJ, Gelboin HV, Galvin M, Langenbach R. Genetic toxicology using human cell lines expressing human P-450 Biochemical Society Transactions. 21: 1023-1028. PMID 8131891 DOI: 10.1042/Bst0211023 |
0.314 |
|
| 1993 |
Nakajima T, Elovaara E, Gonzalez FJ, Gelboin HV, Vainio H, Aoyama T. Characterization of the human cytochrome P450 isozymes responsible for styrene metabolism. Iarc Scientific Publications. 101-108. PMID 8070855 |
0.376 |
|
| 1992 |
Eberhart J, Coffing SL, Anderson JN, Marcus C, Kalogeris TJ, Baird WM, Park SS, Gelboin HV. The time-dependent increase in the binding of benzo[a]pyrene to DNA through (+)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide in primary rat hepatocyte cultures results from induction of cytochrome P450IA1 by benzo[a]pyrene treatment Carcinogenesis. 13: 297-301. PMID 1740021 DOI: 10.1093/Carcin/13.2.297 |
0.388 |
|
| 1992 |
Tamie N, Rui-Sheng W, Elovaara E, Park SS, Gelboin HV, Vainio H. A comparative study on the contribution of cytochrome P450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver Biochemical Pharmacology. 43: 251-257. PMID 1739413 DOI: 10.1016/0006-2952(92)90285-Q |
0.377 |
|
| 1992 |
Tsokos DC, Omata Y, Robinson RC, Krutzsch HC, Gelboin HV, Friedman FK. A proteolytically sensitive region common to several rat liver cytochromes P450: Effect of cleavage on substrate binding Biochemistry. 31: 7155-7159. PMID 1643049 DOI: 10.1021/Bi00146A018 |
0.429 |
|
| 1992 |
Park SS, Walker W, Aoyama T, Lapenson DP, Waxman DJ, Gonzalez FJ, Gelboin HV. Monoclonal antibodies to rat liver microsomal cytochrome b5 Biochemical Pharmacology. 43: 2201-2208. PMID 1599506 DOI: 10.1016/0006-2952(92)90179-M |
0.405 |
|
| 1992 |
Beebe L, Fox SD, Riggs CW, Park SS, Gelboin HV, Issaq HJ, Anderson LM. Persistent effects of a single dose of Aroclor 1254 on cytochromes P450IA1 and IIB1 in mouse lung Toxicology and Applied Pharmacology. 114: 16-24. PMID 1585368 DOI: 10.1016/0041-008X(92)90091-6 |
0.313 |
|
| 1992 |
Rettie AE, Korzekwa KR, Kunze KL, Lawrence RF, Craig Eddy A, Aoyama T, Gelboin HV, Gonzalez FJ, Trager WF. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: A role for P-4502C9 in the etiology of (S)-warfarin - Drug interactions Chemical Research in Toxicology. 5: 54-59. PMID 1581537 DOI: 10.1021/Tx00025A009 |
0.428 |
|
| 1992 |
Hanioka N, Gonzalez FJ, Lindberg NA, Liu G, Gelboin HV, Korzekwa KR. Site-directed mutagenesis of cytochrome P450s CYP2A1 and CYP2A2: influence of the distal helix on the kinetics of testosterone hydroxylation. Biochemistry. 31: 3364-70. PMID 1554718 DOI: 10.1021/Bi00128A009 |
0.342 |
|
| 1992 |
Christou M, Mitchell MJ, Aoyama T, Gelboin HV, Gonzalez FJ, Jefcoate CR. Selective suppression of the catalytic activity of cDNA-expressed cytochrome P4502B1 toward polycyclic hydrocarbons in the microsomal membrane: Modification of this effect by specific amino acid substitutions Biochemistry. 31: 2835-2841. PMID 1547225 DOI: 10.1021/Bi00125A027 |
0.42 |
|
| 1992 |
Tamura S, Korzekwa KR, Kimura S, Gelboin HV, Gonzalez FJ. Baculovirus-mediated expression and functional characterization of human NADPH-P450 oxidoreductase Archives of Biochemistry and Biophysics. 293: 219-223. PMID 1536559 DOI: 10.1016/0003-9861(92)90388-D |
0.432 |
|
| 1992 |
Gonzalez FJ, Gelboin HV. Human cytochromes p450: Evolution and cDNA-directed expression Environmental Health Perspectives. 98: 81-85. PMID 1486867 DOI: 10.1289/Ehp.929881 |
0.412 |
|
| 1992 |
Silvers KJ, Chazinski T, McManus ME, Bauer SL, Gonzalez FJ, Gelboin HV, Maurel P, Howard PC. Cytochrome P-450 3A4 (nifedipine oxidase) is responsible for the C- oxidative metabolism of 1-nitropyrene in human liver microsomal samples Cancer Research. 52: 6237-6243. PMID 1423267 |
0.338 |
|
| 1992 |
Gonzalez FJ, Crespi CL, Czerwinski M, Gelboin HV. Analysis of human cytochrome P450 catalytic activities and expression. Tohoku Journal of Experimental Medicine. 168: 67-72. PMID 1306334 DOI: 10.1620/Tjem.168.67 |
0.444 |
|
| 1991 |
Crespi CL, Penman BW, Gelboin HV, Gonzalez FJ. A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6. Carcinogenesis. 12: 1197-201. PMID 2070484 DOI: 10.1093/Carcin/12.7.1197 |
0.361 |
|
| 1991 |
Gonzalez FJ, Crespi CL, Gelboin HV. DNA-expressed human cytochrome P450s: a new age of molecular toxicology and human risk assessment. Mutation Research. 247: 113-27. PMID 2002797 DOI: 10.1016/0027-5107(91)90039-Q |
0.387 |
|
| 1991 |
Mirvish SS, Huang Q, Ji C, Wang S, Park SS, Gelboin HV. Positional specificity for methyl-n-amylnitrosamine hydroxylation by cytochrome P-450 isozymes determined with monoclonal antibodies Cancer Research. 51: 1059-1064. PMID 1997155 |
0.35 |
|
| 1991 |
Nakajima T, Wang RS, Elovaara E, Park SS, Gelboin HV, Hietanen E, Vainio H. Monoclonal antibody-directed characterization of cytochrome P450 isozymes responsible for toluene metabolism in rat liver Biochemical Pharmacology. 41: 395-404. PMID 1994898 DOI: 10.1016/0006-2952(91)90536-E |
0.388 |
|
| 1991 |
Liu G, Gelboin HV, Myers MJ. Role of cytochrome P450 IA2 in acetanilide 4-hydroxylation as determined with cDNA expression and monoclonal antibodies Archives of Biochemistry and Biophysics. 284: 400-406. PMID 1989524 DOI: 10.1016/0003-9861(91)90315-A |
0.502 |
|
| 1991 |
Sinclair JF, McCaffrey J, Sinclair PR, Bement WJ, Lambrecht LK, Wood SG, Smith EL, Schenkman JB, Guzelian PS, Park SS, Gelboin HV. Ethanol increases cytochromes P450IIE, IIB1/2, and IIIA in cultured rat hepatocytes Archives of Biochemistry and Biophysics. 284: 360-365. PMID 1989519 DOI: 10.1016/0003-9861(91)90308-6 |
0.311 |
|
| 1991 |
Alston K, Robinson RC, Park SS, Gelboin HV, Friedman FK. Interactions among cytochromes P-450 in the endoplasmic reticulum Journal of Biological Chemistry. 266: 735-739. PMID 1985961 |
0.305 |
|
| 1991 |
Elovaara E, Engström K, Nakajima T, Park SS, Gelboin HV, Vainio H. Metabolism of inhaled styrene in acetone-, phenobarbital- and 3-methylcholanthrene-pretreated rats: stimulation and stereochemical effects by induction of cytochromes P450IIE1, P450IIB and P450IA. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 21: 651-61. PMID 1949898 DOI: 10.3109/00498259109039505 |
0.438 |
|
| 1991 |
Crespi CL, Penman BW, Steimel DT, Gelboin HV, Gonzalez FJ. The development of a human cell line stably expressing human CYP3A4: Role in the metabolic activation of aflatoxin B1 and comparison to CYP1A2 and CYP2A3 Carcinogenesis. 12: 355-359. PMID 1899812 DOI: 10.1093/Carcin/12.2.355 |
0.304 |
|
| 1991 |
Waxman DJ, Lapenson DP, Aoyama T, Gelboin HV, Gonzalez FJ, Korzekwa K. Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s. Archives of Biochemistry and Biophysics. 290: 160-6. PMID 1898086 DOI: 10.1016/0003-9861(91)90602-F |
0.446 |
|
| 1991 |
Todorovic R, Devanesan PD, Cavalieri EL, Rogan EG, Park SS, Gelboin HV. A monoclonal antibody to rat liver cytochrome P450 IIC11 strongly and regiospecifically inhibits constitutive benzo[a]pyrene metabolism and DNA binding Molecular Carcinogenesis. 4: 308-314. PMID 1872951 DOI: 10.1002/Mc.2940040409 |
0.441 |
|
| 1991 |
Mirvish SS, Ji C, Huang Q, Wang S, Park SS, Gelboin HV. Use of monoclonal antibodies to identify cytochrome P450 isozymes in rat liver microsomes that hydroxylate N-nitrosomethylamylamine at each of six positions Iarc Scientific Publications. 392-397. PMID 1855887 |
0.371 |
|
| 1991 |
Tyndale R, Aoyama T, Broly F, Matsunaga T, Inaba T, Kalow W, Gelboin HV, Meyer UA, Gonzalez FJ. Identification of a new variant CYP2D6 allele lacking the codon encoding Lys-281: possible association with the poor metabolizer phenotype. Pharmacogenetics. 1: 26-32. PMID 1844820 DOI: 10.1097/00008571-199110000-00005 |
0.405 |
|
| 1991 |
Crespi CL, Gonzalez FJ, Steimel DT, Turner TR, Gelboin HV, Penman BW, Langenbach R. A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. Chemical Research in Toxicology. 4: 566-72. PMID 1793807 DOI: 10.1021/Tx00023A013 |
0.365 |
|
| 1991 |
Gonzalez FJ, Kimura S, Tamura S, Gelboin HV. Expression of mammalian cytochrome P450 using baculovirus Methods in Enzymology. 206: 93-99. PMID 1784251 DOI: 10.1016/0076-6879(91)06080-M |
0.305 |
|
| 1991 |
Nakajima T, Elovaara E, Park SS, Gelboin HV, Vainio H. Immunochemical detection of cytochrome P450 isozymes induced in rat liver by n-hexane, 2-hexanone and acetonyl acetone Archives of Toxicology. 65: 542-547. PMID 1781736 DOI: 10.1007/Bf01973714 |
0.419 |
|
| 1991 |
Gonzalez FJ, Aoyama T, Gelboin HV. Expression of mammalian cytochrome P450 using vaccinia virus Methods in Enzymology. 206: 85-92. PMID 1664484 DOI: 10.1016/0076-6879(91)06079-I |
0.383 |
|
| 1990 |
Riddick DS, Park SS, Gelboin HV, Marks GS. Effects of 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on hepatic cytochrome P-450 heme, apoproteins, and catalytic activities following in vivo administration to rats. Molecular Pharmacology. 37: 130-6. PMID 2405248 |
0.344 |
|
| 1990 |
Tamie N, Elovaara E, Park SS, Gelboin HV, Hietanen E, Vainio H. Monoclonal antibody-directed characterization of benzene, ethoxyresorufin and pentoxyresorufin metabolism in rat liver microsomes Biochemical Pharmacology. 40: 1255-1261. PMID 2403379 DOI: 10.1016/0006-2952(90)90391-W |
0.415 |
|
| 1990 |
Myers MJ, Liu G, Miller H, Gelboin HV, Robinson RC, Friedman FK. Synthetic peptide antigens elicit monoclonal and polyclonal antibodies to cytochrome P450 IA2 Biochemical and Biophysical Research Communications. 169: 171-176. PMID 2350341 DOI: 10.1016/0006-291X(90)91450-7 |
0.34 |
|
| 1990 |
Robinson RC, Nagata K, Gelboin HV, Rifkind J, Gonzalez FJ, Friedman FK. Developmental regulation of hepatic testosterone hydroxylases: Simultaneous activation and repression of constitutively expressed cytochromes P450 in senescent rats Archives of Biochemistry and Biophysics. 277: 42-46. PMID 2306123 DOI: 10.1016/0003-9861(90)90547-C |
0.399 |
|
| 1990 |
Howard PC, Aoyama T, Bauer SL, Gelboin HV, Gonzalez FJ. The metabolism of 1-nitropyrene by human cytochromes P450 Carcinogenesis. 11: 1539-1542. PMID 2205409 DOI: 10.1093/Carcin/11.9.1539 |
0.435 |
|
| 1990 |
Aoyama T, Yamano S, Guzelian PS, Gelboin HV, Gonzalez FJ. Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1 Proceedings of the National Academy of Sciences of the United States of America. 87: 4790-4793. PMID 2162057 DOI: 10.1073/Pnas.87.12.4790 |
0.473 |
|
| 1990 |
Aoyama T, Korzekwa K, Nagata K, Gillette J, Gelboin HV, Gonzalez FJ. Estradiol metabolism by complementary deoxyribonucleic acid-expressed human cytochrome P450s Endocrinology. 126: 3101-3106. PMID 2161748 DOI: 10.1210/Endo-126-6-3101 |
0.482 |
|
| 1990 |
Gelboin HV, Park SS, Aoyama T, Fujino T, Crespi CL, Gonzalez FJ. Mapping of cytochrome P-450 distribution and function with monoclonal antibodies and cDNA expression Princess Takamatsu Symposia. 21: 3-16. PMID 2134683 |
0.348 |
|
| 1990 |
Fujino T, West D, Park SS, Gelboin HV. Studies on the mechanism of monoclonal antibody inhibition of enzyme activity of phenobarbital-induced cytochrome p-450 Pharmacology. 40: 301-311. PMID 2122480 DOI: 10.1159/000138677 |
0.411 |
|
| 1990 |
Lin DX, Malaveille C, Park SS, Gelboin HV, Bartsch H. Contribution of DNA methylation and benzylation to N-nitroso-N-benzyl-methylamine-induced mutagenesis in bacteria: Effects of rat liver cytochrome P450 isozymes and glutathione transferases Carcinogenesis. 11: 1653-1658. PMID 2119260 DOI: 10.1093/Carcin/11.9.1653 |
0.372 |
|
| 1990 |
Mays DC, Hilliard JB, Wong DD, Chambers MA, Park SS, Gelboin HV, Gerber N. Bioactivation of 8-methoxypsoralen and irreversible inactivation by cytochrome P-450 in mouse liver microsomes: Modification by monoclonal antibodies, inhibition of drug metabolism and distribution of covalent adducts Journal of Pharmacology and Experimental Therapeutics. 254: 720-731. PMID 2117068 |
0.358 |
|
| 1990 |
Aoyama T, Nagata K, Yamazoe Y, Kato R, Matsunaga E, Gelboin HV, Gonzalez FJ. Cytochrome 65 potentiation of cytochrome P-450 catalytic activity demonstrated by a vaccinia virus-mediated in situ reconstitution system Proceedings of the National Academy of Sciences of the United States of America. 87: 5425-5429. PMID 2115170 DOI: 10.1073/Pnas.87.14.5425 |
0.383 |
|
| 1990 |
Crespi CL, Steimel DT, Aoyama T, Gelboin HV, Gonzalez FJ. Stable expression of human cytochrome P4501A2 cDNA in human lymphoblastoid cell line: Role of the enzyme in the metabolic activation of aflatoxin B1 Molecular Carcinogenesis. 3: 5-8. PMID 2108694 DOI: 10.1002/Mc.2940030104 |
0.304 |
|
| 1990 |
Wilson JD, Miller H, Gelboin HV, Friedman FK. Variation in inducibility of cytochrome P-450c and aryl hydrocarbon hydroxylase in rat liver, lung, kidney, pancreas and nasopharynx Pharmacology. 41: 256-292. PMID 2092329 DOI: 10.1159/000138729 |
0.419 |
|
| 1990 |
Nhamburo PT, Kimura S, McBride OW, Kozak CA, Gelboin HV, Gonzalez FJ. The human CYP2F gene subfamily: Identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping Biochemistry. 29: 5491-5499. PMID 1974816 DOI: 10.1021/Bi00475A012 |
0.337 |
|
| 1990 |
Awney H, Mostafa M, Gelboin H, Myers M. Cytochrome P450 (P450) mediated H2O2 production and its role in mutagenesis Free Radical Biology and Medicine. 9: 162. DOI: 10.1016/B978-0-08-041749-3.50135-2 |
0.361 |
|
| 1990 |
Gelboin HV, Park SS, Aoyama T, Gonzalez FJ. Inhibitory monoclonal antibodies and cDNA expression for the characterization of cytochrome P450 function European Journal of Pharmacology. 183: 42. DOI: 10.1016/0014-2999(90)91291-I |
0.367 |
|
| 1989 |
Holm KA, Park SS, Gelboin HV, Kupfer D. Monoclonal antibody-directed characterization of rat hepatic P450 catalyzing the ω-1 and ω-2 hydroxylation of prostaglandins Archives of Biochemistry and Biophysics. 269: 664-677. PMID 2919889 DOI: 10.1016/0003-9861(89)90151-3 |
0.456 |
|
| 1989 |
Matsunaga E, Zanger UM, Hardwick JP, Gelboin HV, Meyer UA, Gonzalez FJ. The CYP2D gene subfamily: Analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats Biochemistry. 28: 7349-7355. PMID 2819073 DOI: 10.1021/Bi00444A030 |
0.357 |
|
| 1989 |
Aoyama T, Gonzalez FJ, Gelboin HV. Human cDNA-expressed cytochrome P450 IA2: Mutagen activation and substrate specificity Molecular Carcinogenesis. 2: 192-198. PMID 2803520 DOI: 10.1002/Mc.2940020405 |
0.426 |
|
| 1989 |
Aoyama T, Gonzalez FJ, Gelboin HV. Mutagen activation by cDNA-expressed P1450, P3450, and P450a Molecular Carcinogenesis. 1: 253-259. PMID 2789689 DOI: 10.1002/Mc.2940010408 |
0.412 |
|
| 1989 |
Waxman DJ, Lapenson DP, Morrissey JJ, Park SS, Gelboin HV, Doehmer J, Oesch F. Androgen hydroxylation catalysed by a cell line (SD1) that stably expresses rat hepatic cytochrome P-450 PB-4 (IIB1) Biochemical Journal. 260: 81-85. PMID 2789039 DOI: 10.1042/Bj2600081 |
0.466 |
|
| 1989 |
Friedman FK, Miller H, Park SS, Graham SA, Gelboin HV, Carubelli R. Induction of rat liver microsomal and nuclear cytochrome p-450 by dietary 2-acetylaminofluorene and butylated hydroxytoluene Biochemical Pharmacology. 38: 3075-3081. PMID 2783162 DOI: 10.1016/0006-2952(89)90018-X |
0.438 |
|
| 1989 |
Park SS, Waxman DJ, Lapenson DP, Schenkman JB, Gelboin HV. Monoclonal antibodies to rat liver cytochrome P-450 2c/RLM5 that regiospecifically inhibit steroid metabolism Biochemical Pharmacology. 38: 3067-3074. PMID 2783161 DOI: 10.1016/0006-2952(89)90017-8 |
0.431 |
|
| 1989 |
Nakajima T, Elovaara E, Park SS, Gelboin HV, Hietanen E, Vainio H. Immunochemical characterization of cytochrome P-450 isozymes responsible for benzene oxidation in the rat liver Carcinogenesis. 10: 1713-1717. PMID 2766463 DOI: 10.1093/Carcin/10.9.1713 |
0.459 |
|
| 1989 |
Yamano S, Nagata K, Yamazoe Y, Kato R, Gelboin HV, Gonzalez FJ. cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3) Nucleic Acids Research. 17: 4888. PMID 2748347 DOI: 10.1093/Nar/17.12.4888 |
0.351 |
|
| 1989 |
Khan WA, Park SS, Gelboin HV, Bickers DR, Mukhtar H. Monoclonal antibodies directed characterization of epidermal and hepatic cytochrome P-450 isozymes induced by skin application of therapeutic crude coal tar Journal of Investigative Dermatology. 93: 40-45. PMID 2746006 DOI: 10.1111/1523-1747.Ep12277342 |
0.477 |
|
| 1989 |
Khan WA, Park SS, Gelboin HV, Bickers DR, Mukhtar H. Epidermal cytochrome P-450: Immunochemical characterization of isoform induced by topical application of 3-methylcholanthrene to neonatal rat Journal of Pharmacology and Experimental Therapeutics. 249: 921-927. PMID 2732953 |
0.321 |
|
| 1989 |
Aoyama T, Yamano S, Waxman DJ, Lapenson DP, Meyer UA, Fischer V, Tyndale R, Inaba T, Kalow W, Gelboin HV, Gonzalez FJ. Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine Journal of Biological Chemistry. 264: 10388-10395. PMID 2732228 |
0.354 |
|
| 1989 |
Riddick DS, Park SS, Gelboin HV, Marks GS. Effects of a series of 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on the major inducible cytochrome P-450 isozymes of rat liver. Molecular Pharmacology. 35: 626-34. PMID 2725472 |
0.361 |
|
| 1989 |
Lorr NA, Bloom SE, Park SS, Gelboin HV, Miller H, Friedman FK. Evidence for a PCN-P450 enzyme in chickens and comparison of its development with that of other phenobarbital-inducible forms. Molecular Pharmacology. 35: 610-6. PMID 2725470 |
0.336 |
|
| 1989 |
Aoyama T, Korzekwa K, Nagata K, Gillette J, Gelboin HV, Gonzales FJ. cDNA-directed expression of rat testosterone 7α-hydroxylase using the modified vaccinia virus, T7-RNA-polymerase system and evidence for 6α-hydroxylation and Δ6-testosterone formation European Journal of Biochemistry. 181: 331-336. PMID 2714287 DOI: 10.1111/J.1432-1033.1989.Tb14728.X |
0.424 |
|
| 1989 |
Asseffa A, Smith SJ, Nagata K, Gillette J, Gelboin HV, Gonzalez FJ. Novel exogenous heme-dependent expression of mammalian cytochrome P450 using baculovirus Archives of Biochemistry and Biophysics. 274: 481-490. PMID 2679389 DOI: 10.1016/0003-9861(89)90461-X |
0.381 |
|
| 1989 |
Robinson RC, Shorr RGL, Varrichio A, Park SS, Gelboin HV, Miller H, Friedman FK. Human liver cytochrome P-450 related to a rat acetone-inducible, nitrosamine-mctabolizing cytochrome p-450: Identification and isolation Pharmacology. 39: 137-144. PMID 2587619 DOI: 10.1159/000138590 |
0.469 |
|
| 1989 |
Nhamburo PT, Gonzalez FJ, McBride OW, Gelboin HV, Kimura S. Identification of a new P450 expressed in human lung: Complete cDNA sequence, cDNA-directed expression, and chromosome mapping Biochemistry. 28: 8060-8066. PMID 2574990 DOI: 10.1021/Bi00446A014 |
0.409 |
|
| 1989 |
Khan WA, Kuhn C, Merk HF, Park SS, Gelboin HV, Bickers DR, Mukhtar H. Isozyme-specific monoclonal antibody-directed assessment of induction of hepatic cytochrome P-450 by clotrimazole Drug Metabolism and Disposition. 17: 360-364. PMID 2571472 |
0.347 |
|
| 1989 |
Deutsch J, Vatsis KP, Leutz JC, Coon MJ, Gelboin HV. Studies on covalent binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to cytochromes P-450 LM2 and LM4 and NADPH-cytochrome P-450 reductase. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 19: 1421-35. PMID 2515665 DOI: 10.3109/00498258909043193 |
0.429 |
|
| 1989 |
Lu SJ, Li MH, Park SS, Gelboin HV, Jeffrey AM. Metabolism of fusarin C by rat liver microsomes. Role of esterase and cytochrome P-450 enzymes with respect to the mutagenicity of fusarin C in Salmonella typhimurium. Biochemical Pharmacology. 38: 3811-7. PMID 2512928 DOI: 10.1016/0006-2952(89)90590-X |
0.472 |
|
| 1989 |
Vähäkangas K, Raunio H, Pasanen M, Sivonen P, Park SS, Gelboin HV, Pelkonen O. Comparison of the formation of benzo[a]pyrene diolepoxide-DNA adducts in vitro by rat and human microsomes: evidence for the involvement of P-450IA1 and P-450IA2 Journal of Biochemical Toxicology. 4: 79-86. PMID 2512389 DOI: 10.1002/Jbt.2570040203 |
0.469 |
|
| 1988 |
Gonzalez FJ, Vilbois F, Hardwick JP, McBride OW, Nebert DW, Gelboin HV, Meyer UA. Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22 Genomics. 2: 174-179. PMID 3410476 DOI: 10.1016/0888-7543(88)90100-0 |
0.341 |
|
| 1988 |
Umeno M, Morris S, Matsunaga E, Gelboin HV, Gonzalez FJ. Sequence of the 5' end of the developmentally regulated rat P450 PB1 (P450IIC6) gene Nucleic Acids Research. 16: 6249. PMID 3399405 DOI: 10.1093/Nar/16.13.6249 |
0.346 |
|
| 1988 |
Dong Z, Hong J, Ma Q, Li D, Bullock J, Gonzalez FJ, Park SS, Gelboin HV, Yang CS. Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats Archives of Biochemistry and Biophysics. 263: 29-35. PMID 3285794 DOI: 10.1016/0003-9861(88)90610-8 |
0.34 |
|
| 1988 |
Gonzalez FJ, Schmid BJ, Umeno M, McBride OW, Hardwick JP, Meyer UA, Gelboin HV, Idle JR. Human P450PCN1: Sequence, chromosome localization, and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase Dna. 7: 79-86. PMID 3267210 |
0.366 |
|
| 1988 |
Ladona MG, Park SS, Gelboin HV, Hammar L, Rane A. Monoclonal antibody directed detection of cytochrome P-450 (PCN) in human fetal liver Biochemical Pharmacology. 37: 4735-4741. PMID 3264502 DOI: 10.1016/0006-2952(88)90345-0 |
0.428 |
|
| 1988 |
Pacifici GM, Park SS, Gelboin HV, Rane A. 7-Ethoxycoumarin and 7-ethhoxyresorufin O-deethylase in human foetal and adult liver: Studies with monoclonal antibodies Pharmacology and Toxicology. 63: 26-29. PMID 3261011 DOI: 10.1111/J.1600-0773.1988.Tb00903.X |
0.424 |
|
| 1988 |
Honkakoski P, Autio S, Juvonen R, Raunio H, Gelboin HV, Park SS, Pelkonen O, Lang MA. Pyrazole is different from acetone and ethanol as an inducer of the polysubstrate monooxygenase system in mice: Evidence that pyrazole-inducible P450Coh is distinct from acetone-lnducible P450ac Archives of Biochemistry and Biophysics. 267: 589-598. PMID 3214171 DOI: 10.1016/0003-9861(88)90066-5 |
0.384 |
|
| 1988 |
Matsunaga T, Nagata K, Holsztynska EJ, Lapenson DP, Smith A, Kato R, Gelboin HV, Waxman DJ, Gonzalez FJ. Gene conversion and differential regulation in the rat P-450 IIA gene subfamily. Purification, catalytic activity, cDNA and deduced amino acid sequence, and regulation of an adult male-specific hepatic testosterone 15α-hydroxylase Journal of Biological Chemistry. 263: 17995-18002. PMID 3192524 |
0.311 |
|
| 1988 |
Faletto MB, Koser PL, Battula N, Townsend GK, Maccubbin AE, Gelboin HV, Gurtoo HL. Cytochrome P3-450 cDNA encodes aflatoxin B1-4-hydroxylase Journal of Biological Chemistry. 263: 12187-12189. PMID 3137222 |
0.319 |
|
| 1988 |
Gonzalez FJ, Skoda RC, Kimura S, Umeno M, Zanger UM, Nebert DW, Gelboin HV, Hardwick JP, Meyer UA. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism Nature. 331: 442-446. PMID 3123997 DOI: 10.1038/331442A0 |
0.346 |
|
| 1988 |
Raunio H, Kojo A, Juvonen R, Honkakoski P, Järvinen P, Lang MA, Vähäkangas K, Gelboin HV, Park SS, Pelkonen O. Mouse hepatic cytochrome p-450 isozyme induction by 1,4-bis[2-(3,5-dichloropyridyloxy)] benzene, pyrazole, and phenobarbital Biochemical Pharmacology. 37: 4141-4147. PMID 2903743 DOI: 10.1016/0006-2952(88)90108-6 |
0.409 |
|
| 1987 |
Hong J, Pan J, Gonzalez FJ, Gelboin HV, Yang CS. The induction of a specific form of cytochrome P-450 (P-450j) by fasting Biochemical and Biophysical Research Communications. 142: 1077-1083. PMID 3827895 DOI: 10.1016/0006-291X(87)91525-7 |
0.434 |
|
| 1987 |
Nagata K, Matsunaga T, Gillette J, Gelboin HV, Gonzalez FJ. Rat testosterone 7 alpha-hydroxylase. Isolation, sequence, and expression of cDNA and its developmental regulation and induction by 3-methylcholanthrene Journal of Biological Chemistry. 262: 2787-2793. PMID 3818621 |
0.308 |
|
| 1987 |
Khan WA, Asokan P, Park SS, Gelboin HV, Bickers DR, Mukhtar H. Use of monoclonal antibodies to characterize the induction response of the cytochrome P-450-dependent mixed function oxidase system to nitrofluoranthenes Carcinogenesis. 8: 1679-1684. PMID 3664959 DOI: 10.1093/Carcin/8.11.1679 |
0.426 |
|
| 1987 |
Pasanen M, Pelkonen O, Kauppila A, Park SS, Friedman FK, Gelboin HV. Characterization of human fetal hepatic cytochrome P-450-associated 7-ethoxyresorufin O-deethylase and aryl hydrocarbon hydroxylase activities by monoclonal antibodies Developmental Pharmacology and Therapeutics. 10: 125-132. PMID 3608743 DOI: 10.1159/000457737 |
0.464 |
|
| 1987 |
Ueng TH, Friedman FK, Miller H, Park SS, Gelboin HV, Alvares AP. Studies on ethanol-inducible cytochrome P-450 in rabbit liver, lungs and kidneys Biochemical Pharmacology. 36: 2689-2691. PMID 3606668 DOI: 10.1016/0006-2952(87)90554-5 |
0.348 |
|
| 1987 |
Kapitulnik J, Hardwick JP, Ostrow JD, Webster CC, Park SS, Gelboin HV. Increase in a specific cytochrome P-450 isoenzyme in the liver of congenitally jaundiced Gunn rats Biochemical Journal. 242: 297-300. PMID 3593244 DOI: 10.1042/Bj2420297 |
0.445 |
|
| 1987 |
Kloepper-Sams PJ, Park SS, Gelboin HV, Stegeman JJ. Specificity and cross-reactivity of monoclonal and polyclonal antibodies against cytochrome P-450E of the marine fish scup Archives of Biochemistry and Biophysics. 253: 268-278. PMID 3545085 DOI: 10.1016/0003-9861(87)90660-6 |
0.402 |
|
| 1987 |
Hietanen E, Ahotupa M, Béréziat Jc, Park SS, Gelboin HV, Bartsch H. Monoclonal antibody characterization of hepatic and extrahepatic cytochrome P-450 activities in rats treated with phenobarbital or methylcholanthrene and fed various cholesterol diets Biochemical Pharmacology. 36: 3973-3980. PMID 3500724 DOI: 10.1016/0006-2952(87)90466-7 |
0.391 |
|
| 1987 |
Malaveille C, Brun G, Park SS, Gelboin HV, Bartsch H. A monoclonal antibody against cytochrome P-450 enhances mutagen activation of N-nitrosodimethylamine by mouse liver S9: Studies on the mode of action Carcinogenesis. 8: 1775-1779. PMID 3315287 |
0.334 |
|
| 1987 |
Song BJ, Matsunaga T, Hardwick JP, Park SS, Veech RL, Yang CS, Gelboin HV, Gonzalez FJ. Stabilization of cytochrome P450j messenger ribonucleic acid in the diabetic rat Molecular Endocrinology (Baltimore, Md.). 1: 542-547. PMID 3153476 DOI: 10.1210/Mend-1-8-542 |
0.341 |
|
| 1987 |
Waxman DJ, Lapenson DP, Park SS, Attisano C, Gelboin HV. Monoclonal antibodies in hibitory to rat hepatic cytochromes P-450: P-450 form specificities and use as probes for cytochrome P-450-dependent steroid hydroxylations Molecular Pharmacology. 32: 615-624. PMID 3119986 |
0.385 |
|
| 1987 |
Ko IY, Park SS, Song BJ, Patten C, Tan YZ, Hah YC, Yang CS, Gelboin HV. Monoclonal antibodies to ethanol-induced rat liver cytochrome P-450 that metabolizes aniline and nitrosamines. Cancer Research. 47: 3101-9. PMID 3107803 |
0.399 |
|
| 1987 |
Battula N, Sagara J, Gelboin HV. Expression of P1-450 and P3-450 DNA coding sequences as enzymatically active cytochromes P-450 in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 4073-7. PMID 3035566 DOI: 10.1073/Pnas.84.12.4073 |
0.433 |
|
| 1987 |
Slusher LB, Park SS, Gelboin HV, Vesell ES. Studies on the metabolism of aminopyrine, antipyrine and theophylline using monoclonal antibodies to cytochrome P-450 isozymes purified from rat liver Biochemical Pharmacology. 36: 2359-2367. PMID 2440440 DOI: 10.1016/0006-2952(87)90604-6 |
0.46 |
|
| 1986 |
Friedman FK, Robinson RC, Song BJ, Park SS, Gelboin HV. Preparation of catalytically active cytochromes P-450 by antigen exchange on monoclonal antibody based immunoadsorbents. Biochemistry. 24: 7044-8. PMID 4084558 DOI: 10.1021/Bi00346A003 |
0.435 |
|
| 1986 |
Friedman FK, Park SS, Gelboin HV. The application of monoclonal antibodies for studies on cytochrome P-450. Reviews On Drug Metabolism and Drug Interactions. 5: 159-92. PMID 3915825 DOI: 10.1515/Dmdi.1985.5.2-3.159 |
0.351 |
|
| 1986 |
Friedman FK, West D, Dewick PM, Gelboin HV. Specificity of medicarpin and related isoflavonoids in inhibition of rat hepatic mixed function oxidase activity. Pharmacology. 31: 289-93. PMID 3877941 DOI: 10.1159/000138134 |
0.477 |
|
| 1986 |
Robinson RC, Cheng KC, Park SS, Gelboin HV, Friedman FK. Structural comparison of monoclonal antibody immunopurified pulmonary and hepatic cytochrome P-450 from 3-methylcholanthrene-treated rats. Biochemical Pharmacology. 35: 3827-30. PMID 3778507 DOI: 10.1016/0006-2952(86)90671-4 |
0.452 |
|
| 1986 |
Friedman FK, Park SS, Song BJ, Cheng KC, Fujino T, Gelboin HV. Monoclonal antibody-directed analysis of cytochrome P-450. Advances in Experimental Medicine and Biology. 197: 145-54. PMID 3766255 DOI: 10.1007/978-1-4684-5134-4_11 |
0.406 |
|
| 1986 |
Pelkonen O, Pasanen M, Kuha H, Gachalyi B, Kairaluoma M, Sotaniemi EA, Park SS, Friedman FK, Gelboin HV. The effect of cigarette smoking on 7-ethoxyresorufin O-deethylase and other monooxygenase activities in human liver: analyses with monoclonal antibodies. British Journal of Clinical Pharmacology. 22: 125-34. PMID 3756062 DOI: 10.1111/J.1365-2125.1986.Tb05239.X |
0.396 |
|
| 1986 |
Fagan JB, Pastewka JV, Chalberg SC, Gozukara E, Guengerich FP, Gelboin HV. Noncoordinate regulation of the mRNAs encoding cytochromes P-450BNF/MC-B and P-450ISF/BNF-G. Archives of Biochemistry and Biophysics. 244: 261-72. PMID 3753838 DOI: 10.1016/0003-9861(86)90116-5 |
0.35 |
|
| 1986 |
Park SS, Waxman DJ, Miller H, Robinson R, Attisano C, Guengerich FP, Gelboin HV. Preparation and characterization of monoclonal antibodies to pregnenolone 16-alpha-carbonitrile inducible rat liver cytochrome P-450. Biochemical Pharmacology. 35: 2859-67. PMID 3488743 DOI: 10.1016/0006-2952(86)90477-6 |
0.438 |
|
| 1986 |
Park SS, Miller H, Klotz AV, Kloepper-Sams PJ, Stegeman JJ, Gelboin HV. Monoclonal antibodies to liver microsomal cytochrome P-450E of the marine fish Stenotomus chrysops (scup): cross reactivity with 3-methylcholanthrene induced rat cytochrome P-450. Archives of Biochemistry and Biophysics. 249: 339-50. PMID 2428309 DOI: 10.1016/0003-9861(86)90010-X |
0.451 |
|
| 1986 |
Park SS, Ko IY, Patten C, Yang CS, Gelboin HV. Monoclonal antibodies to ethanol induced cytochrome P-450 that inhibit aniline and nitrosamine metabolism. Biochemical Pharmacology. 35: 2855-8. PMID 2427088 DOI: 10.1016/0006-2952(86)90476-4 |
0.367 |
|
| 1986 |
Song BJ, Gelboin HV, Park SS, Friedman FK. Epitope-relatedness and phenotyping of hepatic cytochromes P-450 with monoclonal antibodies. The Biochemical Journal. 231: 671-6. PMID 2416310 DOI: 10.1042/BJ2310671 |
0.352 |
|
| 1985 |
Wiebel FJ, Park SS, Kiefer F, Gelboin HV. Expression of cytochromes P-450 in rat hepatoma cells. Analysis by monoclonal antibodies specific for cytochromes P-450 from rat liver induced by 3-methylcholanthrene or phenobarbital. European Journal of Biochemistry. 145: 455-62. PMID 6334605 DOI: 10.1111/J.1432-1033.1984.Tb08577.X |
0.431 |
|
| 1985 |
Friedman FK, West D, Sugimura T, Gelboin HV. Flavone modulators of rat hepatic aryl hydrocarbon hydroxylase. Pharmacology. 31: 203-7. PMID 4059325 DOI: 10.1159/000138116 |
0.467 |
|
| 1985 |
Friedman FK, Wiebel FJ, Gelboin HV. Modulation of rat hepatic aryl hydrocarbon hydroxylase by various flavones and polycyclic aromatic hydrocarbons. Pharmacology. 31: 194-202. PMID 4059324 DOI: 10.1159/000138115 |
0.387 |
|
| 1985 |
Friedman FK, Robinson RC, Krutzsch HC, Grantham PH, Park SS, Gelboin HV. Monoclonal antibody directed isolation and amino-terminal sequence analysis of phenobarbital induced rat liver cytochromes P-450. Biochemical and Biophysical Research Communications. 129: 926-33. PMID 4015658 DOI: 10.1016/0006-291X(85)91980-1 |
0.438 |
|
| 1985 |
Friedman FK, Robinson RC, Park SS, Gelboin HV. Catalytic activity of cytochromes P-450 purified by monoclonal antibody-directed immunopurification. Biochemical Pharmacology. 34: 2051-4. PMID 4004923 DOI: 10.1016/0006-2952(85)90336-3 |
0.388 |
|
| 1985 |
Gelboin HV, Friedman FK. Monoclonal antibodies for studies on xenobiotic and endobiotic metabolism. Cytochromes P-450 as paradigm. Biochemical Pharmacology. 34: 2225-34. PMID 3893437 DOI: 10.1016/0006-2952(85)90776-2 |
0.38 |
|
| 1985 |
Friedman FK, Pastewka JV, Robinson RC, Park SS, Marletta MA, Gelboin HV. Monoclonal antibodies to cytochrome P-450 immunopurify a 45-kDa protein from a human lymphoblastoid cell line. Febs Letters. 185: 67-70. PMID 2581816 DOI: 10.1016/0014-5793(85)80742-0 |
0.441 |
|
| 1985 |
Song BJ, Gelboin HV, Park SS, Tsokos GC, Friedman FK. Monoclonal antibody-directed radioimmunoassay detects cytochrome P-450 in human placenta and lymphocytes. Science (New York, N.Y.). 228: 490-2. PMID 2580351 DOI: 10.1126/Science.2580351 |
0.3 |
|
| 1985 |
Stegeman JJ, Woodin BR, Park SS, Kloepper-Sams PJ, Gelboin HV. Microsomal cytochrome P-450 function in fish evaluated with polyclonal and monoclonal antibodies to cytochrome P-450E from scup (Stenotomus chrysops) Marine Environmental Research. 17: 83-86. DOI: 10.1016/0141-1136(85)90045-5 |
0.433 |
|
| 1984 |
Friedman FK, Robinson RC, Park SS, Gelboin HV. Monoclonal antibody-directed immunopurification and identification of cytochromes P-450. Biochemical and Biophysical Research Communications. 116: 859-65. PMID 6651850 DOI: 10.1016/S0006-291X(83)80221-6 |
0.464 |
|
| 1984 |
Cheng KC, Krutzsch HC, Park SS, Grantham PH, Gelboin HV, Friedman FK. Amino-terminal sequence analysis of six cytochrome P-450 isozymes purified by monoclonal antibody directed immunopurification. Biochemical and Biophysical Research Communications. 123: 1201-8. PMID 6487327 DOI: 10.1016/S0006-291X(84)80260-0 |
0.327 |
|
| 1984 |
Gozukara EM, Fagan J, Pastewka JV, Guengerich FP, Gelboin HV. Induction of cytochrome P-450 mRNAs quantitated by in vitro translation and immunoprecipitation. Archives of Biochemistry and Biophysics. 232: 660-9. PMID 6465891 DOI: 10.1016/0003-9861(84)90586-1 |
0.356 |
|
| 1984 |
Park SS, Fujino T, Miller H, Guengerich FP, Gelboin HV. Monoclonal antibodies to phenobarbital-induced rat liver cytochrome P-450. Biochemical Pharmacology. 33: 2071-81. PMID 6331457 DOI: 10.1016/0006-2952(84)90576-8 |
0.484 |
|
| 1983 |
Fagan JB, Pastewka JV, Park SS, Guengerich FP, Gelboin HV. Identification and quantitation of a 2.0-kilobase messenger ribonucleic acid coding for 3-methylcholanthrene-induced cytochrome P-450 using cloned cytochrome P-450 complementary deoxyribonucleic acid. Biochemistry. 21: 6574-80. PMID 6897517 DOI: 10.1021/Bi00268A039 |
0.426 |
|
| 1983 |
Thorgeirsson SS, Sanderson N, Park SS, Gelboin HV. Inhibition of 2-acetylaminofluorene oxidations by monoclonal antibodies specific to 3-methylcholanthrene-induced rat liver cytochrome P450. Carcinogenesis. 4: 639-41. PMID 6850996 DOI: 10.1093/CARCIN/4.5.639 |
0.359 |
|
| 1983 |
Fagan J, Pastewka J, Guengerich F, Gelboin H. Multiple cytochromes P-450 are translated from multiple messenger ribonucleic acids. Biochemistry. 22: 1927-34. PMID 6849896 DOI: 10.1021/Bi00277A029 |
0.355 |
|
| 1982 |
Fujino T, Park SS, West D, Gelboin HV. Phenotyping of cytochromes P-450 in human tissues with monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 79: 3682-6. PMID 6980417 DOI: 10.1073/Pnas.79.12.3682 |
0.474 |
|
| 1982 |
Gozukara EM, Guengerich FP, Miller H, Gelboin HV. Different patterns of benzo[a]pyrene metabolism of purified cytochromes P-450 from methylcholanthrene, beta-naphthoflavone and phenobarbital treated rats. Carcinogenesis. 3: 129-33. PMID 6279326 DOI: 10.1093/Carcin/3.2.129 |
0.408 |
|
| 1981 |
Gelboin HV, West D, Gozukara E, Natori S, Nagao M, Sugimura T. (-)Maackiain acetate specifically inhibits different forms of aryl hydrocarbon hydroxylase in rat and man. Nature. 291: 659-61. PMID 7242671 DOI: 10.1038/291659A0 |
0.447 |
|
| 1981 |
Okano P, Whitlock JP, Gelboin HV. Aryl hydrocarbon hydroxylase and benzo[a] pyrene metabolism in rodent liver and human cels. Annals of the New York Academy of Sciences. 349: 232-46. PMID 6164323 DOI: 10.1111/J.1749-6632.1980.Tb29530.X |
0.372 |
|
| 1980 |
Robie-Suh K, Robinson R, Gelboin HV, Guengerich FP. Aryl hydrocarbon hydroxylase is inhibited by antibody to rat liver cytochrome P-450. Science (New York, N.Y.). 208: 1031-3. PMID 7375915 DOI: 10.1126/Science.7375915 |
0.489 |
|
| 1980 |
Belvedere G, Miller H, Vatsis KP, Coon MJ, Gelboin HV. Hydroxylation of benzo[a]pyrene and binding of (-)trans 5-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to deoxyribonucleic acid catalyzed by purified forms of rabbit liver microsomal cytochrome P-450. Effect of 7,8-benzoflavone, butylated hydroxytoluene and ascorbic acid Biochemical Pharmacology. 29: 1693-1702. PMID 7190824 DOI: 10.1016/0006-2952(80)90127-6 |
0.497 |
|
| 1980 |
Park SS, Persson AV, Coon MJ, Gelboin HV. Monoclonal antibodies to rabbit liver cytochrome P450 LM2 Febs Letters. 116: 231-235. PMID 6773800 DOI: 10.1016/0014-5793(80)80651-X |
0.461 |
|
| 1980 |
McIntosh PR, Peacock AC, Gelboin HV. The induction of liver microsomal proteins by 3-methylcholanthrene in rats of different age, sex and strain. Biochimica Et Biophysica Acta. 627: 290-300. PMID 6766329 DOI: 10.1016/0304-4165(80)90460-2 |
0.333 |
|
| 1980 |
Vatsis KP, Deutsche J, Gelboin HV, Coon MJ. CATALYTIC ACTIVITY AND STEREOSPECIFICITY OF PHENOBARBITAL-INDUCIBLE AND 5,6-BENZOFLAVONE-INDUCIBLE ISOZYMES OF LIVER MICROSOMAL CYTOCHROME P-450 IN THE OXYGENATION OF BENZO[a]-PYRENE AND trans-7,8-DIHYDROXY-7,8-DIHYDROBENZO[a]PYRENE Microsomes, Drug Oxidations and Chemical Carcinogenesis. 1065-1080. DOI: 10.1016/B978-0-12-187702-6.50090-6 |
0.438 |
|
| 1980 |
Guengerich FP, Wang P, Mason PS, Robie-Suh K, Robinson RC, Gelboin HV. Immunological Cross-Reactivity Of Rat Liver And Human Cytochromes P-450 Microsomes, Drug Oxidations and Chemical Carcinogenesis. 127-130. DOI: 10.1016/B978-0-12-187701-9.50022-X |
0.437 |
|
| 1978 |
Nemoto N, Takayama S, Gelboin HV. Sulfate conjugation of benzo[alpha]pyrene metabolites and derivates. Chemico-Biological Interactions. 23: 19-30. PMID 699189 DOI: 10.1016/0009-2797(78)90039-X |
0.341 |
|
| 1978 |
Deutsch J, Leutz JC, Yang SK, Gelboin HV, Chiang YL, Vatsis KP, Coon MJ. Regio- and stereoselectivity of various forms of purified cytochrome P-450 in the metabolism of benzo[a]pyrene and (-) trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene as shown by product formation and binding to DNA. Proceedings of the National Academy of Sciences of the United States of America. 75: 3123-7. PMID 277915 DOI: 10.1073/Pnas.75.7.3123 |
0.435 |
|
| 1977 |
Brown S, Wiebel FJ, Gelboin HV, Minna JD. Assignment of a locus required for flavoprotein-linked monooxygenase expression to human chromosome 2. Proceedings of the National Academy of Sciences of the United States of America. 73: 4628-32. PMID 1070014 DOI: 10.1073/Pnas.73.12.4628 |
0.317 |
|
| 1976 |
Wiebel FJ, Gelboin HV. Aryl hydrocarbon (benzo[a]pyrene) hydroxylases in liver from rats of different age, sex and nutritional status. Distinction of two types by 7,8-benzoflavone. Biochemical Pharmacology. 24: 1511-5. PMID 1191309 DOI: 10.1016/0006-2952(75)90028-3 |
0.367 |
|
| 1976 |
Wiebel FJ, Selkirk JK, Gelboin HV, Haugen DA, van der Hoeven TA, Coon MJ. Position-specific oxygenation of benzo(a)pyrene by different forms of purified cytochrome P-450 from rabbit liver. Proceedings of the National Academy of Sciences of the United States of America. 72: 3917-20. PMID 1060073 DOI: 10.1073/Pnas.72.10.3917 |
0.441 |
|
| 1976 |
Nemoto N, Gelboin H. Assay and properties of glutathione-S-benzo(a)pyrene-4,5-oxide transferase. Archives of Biochemistry and Biophysics. 170: 739-42. PMID 242265 DOI: 10.1016/0003-9861(75)90172-1 |
0.36 |
|
| 1975 |
Whitlock JP, Miller H, Gelboin HV. Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture. The Journal of Cell Biology. 63: 136-45. PMID 4153658 DOI: 10.1083/Jcb.63.1.136 |
0.353 |
|
| 1975 |
Nemoto N, Gelboin HV, Habig WH, Ketley JN, Jakoby WB. K region benzo (alpha) pyrene-4,5-oxide is conjugated by homogeneous gluthathione S-transferases. Nature. 255: 512-512. PMID 1138205 DOI: 10.1038/255512A0 |
0.314 |
|
| 1975 |
Leutz JC, Gelboin HV. Benzo(a)pyrene-4,5-oxide hydratase: assay, properties, and induction. Archives of Biochemistry and Biophysics. 168: 722-5. PMID 1137413 DOI: 10.1016/0003-9861(75)90307-0 |
0.317 |
|
| 1975 |
Wiebel FJ, Leutz JC, Gelboin HV. Aryl hydrocarbon (benzo[a]pyrene) hydroxylase: a mixed-function oxygenase in mouse skin. The Journal of Investigative Dermatology. 64: 184-9. PMID 234991 DOI: 10.1111/1523-1747.Ep12533351 |
0.308 |
|
| 1974 |
Bast RC, Whitlock JP, Miller H, Rapp HJ, Gelboin HV. Aryl hydrocarbon (benzo(a)pyrene) hydroxylase in human peripheral blood monocytes Nature. 250: 664-665. PMID 4850643 DOI: 10.1038/250664A0 |
0.365 |
|
| 1974 |
Wiebel FJ, Matthews EJ, Gelboin HV. On the relationship between transcription, translation, and ribosomal RNA synthesis during microsomal hydroxylase induction. Basic Life Sciences. 1: 459-72. PMID 4797929 DOI: 10.1007/978-1-4684-0877-5_35 |
0.334 |
|
| 1973 |
Wiebel FJ, Leutz JC, Gelboin HV. Aryl hydrocarbon (benzo ( ) pyrene) hydroxylase: inducible in extrahepatic tissues of mouse strains not inducible in liver. Archives of Biochemistry and Biophysics. 154: 292-4. PMID 4689780 DOI: 10.1016/0003-9861(73)90060-X |
0.305 |
|
| 1972 |
Wiebel FJ, Leutz JC, Diamond L, Gelboin HV. Aryl hydrocarbon (benzo(a)pyrene) hydroxylase in microsomes from rat tissues: differential inhibition and stimulation by benzoflavones and organic solvents. Archives of Biochemistry and Biophysics. 144: 78-86. PMID 5117540 DOI: 10.1016/0003-9861(71)90456-5 |
0.368 |
|
| 1972 |
Kinoshita N, Gelboin HV. Aryl hydrocarbon hydroxylase and polycyclic hydrocarbon tumorigenesis: effect of the enzyme inhibitor 7,8-benzoflavone on tumorigenesis and macromolecule binding. Proceedings of the National Academy of Sciences of the United States of America. 69: 824-8. PMID 4502935 DOI: 10.1073/Pnas.69.4.824 |
0.312 |
|
| 1972 |
Whitlock JP, Cooper HL, Gelboin HV. Aryl hydrocarbon (benzopyrene) hydroxylase is stimulated in human lymphocytes by mitogens and benz[a]anthracene Science. 177: 618-619. PMID 4403140 DOI: 10.1126/Science.177.4049.618 |
0.303 |
|
| 1970 |
Younger LR, Gelboin HV. The electrophoretic distribution of RNA synthesized in vitro by isolated rat liver nuclei. Biochimica Et Biophysica Acta. 204: 168-74. PMID 5437665 DOI: 10.1016/0005-2787(70)90499-5 |
0.313 |
|
| 1970 |
Gelboin HV, Huberman E, Sachs L. Enzymatic hydroxylation of benzopyrene and its relationship to cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 64: 1188-94. PMID 4318345 DOI: 10.1073/Pnas.64.4.1188 |
0.333 |
|
| 1969 |
Diamond L, Gelboin HV. Alpha-naphthoflavone: an inhibitor of hydrocarbon cytotoxicity and microsomal hydroxylase. Science (New York, N.Y.). 166: 1023-5. PMID 5347522 DOI: 10.1126/Science.166.3908.1023 |
0.368 |
|
| 1969 |
Nebert DW, Gelboin HV. The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states. Archives of Biochemistry and Biophysics. 134: 76-89. PMID 4981257 DOI: 10.1016/0003-9861(69)90253-7 |
0.396 |
|
| 1967 |
Gelboin HV, Wortham JS, Wilson RG. 3-methylcholanthrene and phenobarbital stimulation of rat liver RNA polymerase. Nature. 214: 281-283. PMID 6034244 DOI: 10.1038/214281A0 |
0.394 |
|
| 1967 |
Alfred LJ, Gelboin HV. Benzpyrene hydroxylase induction by polycyclic hydrocarbons in hamster embryonic cells grown in vitro. Science (New York, N.Y.). 157: 75-6. PMID 6026668 DOI: 10.1126/Science.157.3784.75 |
0.332 |
|
| 1967 |
Gelboin HV, Wortham JS, Wilson RG, Friedman M, Wogan GN. Rapid and marked inhibition of rat-liver RNA polymerase by aflatoxin B-1. Science (New York, N.Y.). 154: 1205-6. PMID 5921386 DOI: 10.1126/Science.154.3753.1205 |
0.329 |
|
| 1966 |
Kato R, Jondorf WR, Loeb LA, Ben T, Gelboin HV. Studies on the mechanism of drug-induced microsomal enzyme activities. V. Phenobarbital stimulation of endogenous messenger RNA and polyuridylic acid-directed L-[14C]-phenylalanine incorporation. Molecular Pharmacology. 2: 171-86. PMID 5905664 |
0.451 |
|
| 1965 |
Kato R, Loeb L, Gelboin HV. Increased Sensitivity Of Microsomes From Phenobarbital-Treated Rats To Synthetic Messenger Rna (Polyuridylic Acid): Lack Of Effect On Ribosomes. Nature. 205: 668-669. PMID 14287402 DOI: 10.1038/205668A0 |
0.318 |
|
| 1964 |
LOEB LA, GELBOIN HV. METHYLCHOLANTHRENE-INDUCED CHANGES IN RAT LIVER NUCLEAR RNA. Proceedings of the National Academy of Sciences of the United States of America. 52: 1219-26. PMID 14231444 DOI: 10.1073/Pnas.52.5.1219 |
0.528 |
|
| 1964 |
GELBOIN HV, SOKOLOFF L. STUDIES ON THE MECHANISM OF METHYLCHOLANTHRENE INDUCTION OF ENZYME ACTIVITIES OF RAT LIVER. I. AMINO ACID INCORPORATION IN RAT-LIVER HOMOGENATES. Biochimica Et Biophysica Acta. 91: 122-9. PMID 14227258 DOI: 10.1016/0926-6550(64)90176-8 |
0.566 |
|
| 1964 |
Gelboin HV. Studies on the mechanism of methylcholanthrene induction of enzyme activities Biochimica Et Biophysica Acta (Bba) - Specialized Section On Nucleic Acids and Related Subjects. 91: 130-144. DOI: 10.1016/0926-6550(64)90177-X |
0.392 |
|
| 1963 |
LOEB LA, GELBOIN HV. STIMULATION OF AMINO-ACID INCORPORATION BY NUCLEAR RIBONUCLEIC ACID FROM NORMAL AND METHYLCHOLANTHRENE-TREATED RATS. Nature. 199: 809-10. PMID 14071196 DOI: 10.1038/199809A0 |
0.559 |
|
| 1963 |
GELBOIN HV, SOKOLOFF L. EFFECT OF 3-METHYLCHOLANTHRENE ON AMINO ACID INCORPORATION INTO RAT LIVER PROTEIN. Acta - Unio Internationalis Contra Cancrum. 19: 568-70. PMID 14054096 |
0.483 |
|
| 1963 |
SOKOLOFF L, KAUFMAN S, CAMPBELL PL, FRANCIS CM, GELBOIN HV. Thyroxine stimulation of amino acid incorporation into protein. Localization of stimulated step. The Journal of Biological Chemistry. 238: 1432-7. PMID 13977956 |
0.384 |
|
| 1963 |
Gelboin HV, Blackburn NR. The stimulatory effect of 3-methylcholanthrene on microsomal amino acid incorporation and benzpyrene hydroxylase activity and its inhibition by actinomycin D Biochimica Et Biophysica Acta (Bba) - Specialized Section On Nucleic Acids and Related Subjects. 72: 657-660. DOI: 10.1016/0926-6550(63)90394-3 |
0.303 |
|
| 1962 |
CANTONI GL, GELBOIN HV, LUBORSKY SW, RICHARDS HH, SINGER MF. Studies on soluble ribonucleic acid of rabbit liver. II. Preparation and properties of rabbit-liver soluble RNA. Biochimica Et Biophysica Acta. 61: 354-67. PMID 14018363 DOI: 10.1016/0926-6550(62)90136-6 |
0.609 |
|
| 1962 |
Cantoni GL, Gelboin HV, Luborsky SW, Richards HH, Singer MF. Studies on soluble ribonucleic acid of rabbit liver III. Preparation and properties of rabbit-liver soluble RNA Bba Specialized Section On Nucleic Acids and Related Subjects. 61: 354-367. |
0.575 |
|
| 1961 |
SOKOLOFF L, KAUFMAN S, GELBOIN HV. Thyroxine stimulation of soluble ribonucleic acid bound amino acid transfer to microsomal protein. Biochimica Et Biophysica Acta. 52: 410-2. PMID 13914852 DOI: 10.1016/0006-3002(61)90701-6 |
0.467 |
|
| 1961 |
GELBOIN HV, SOKOLOFF L. Effects of 3-methylcholanthrene and phenobarbital on amino acid incorporation into protein. Science (New York, N.Y.). 134: 611-2. PMID 13704253 |
0.474 |
|
| 1959 |
GELBOIN HV, MILLER JA, MILLER EC. The in vitro formation of protein-bound derivatives of aminoazo dyes by rat liver preparations. Cancer Research. 19: 975-85. PMID 13827171 |
0.559 |
|
| 1958 |
GELBOIN HV, MILLER JA, MILLER EC. Studies on hepatic protein-bound dye formation in rats given single large doses of 3'methyl-4-dimethylaminoazobenzene. Cancer Research. 18: 608-17. PMID 13547059 |
0.508 |
|
| 1958 |
GELBOIN HV, MILLER JA, MILLER EC. The formation in vitro of proteinbound derivatives of aminoazo dyes by rat liver and its enhancement by benzpyrene pretreatment. Biochimica Et Biophysica Acta. 27: 655-6. PMID 13535659 |
0.558 |
|
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