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Lydia Borgelt - Publications

Affiliations: 
Max Planck Institute for Molecular Physiology 
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Borgelt L, Hohnen L, Pallesen JS, Hommen P, Goebel GL, Bosica F, Liu Y, O'Mahony G, Wu P. -Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28- Interaction. Acs Medicinal Chemistry Letters. 14: 1707-1715. PMID 38116413 DOI: 10.1021/acsmedchemlett.3c00341  0.841
2023 Borgelt L, Wu P. Targeting Ribonucleases with Small Molecules and Bifunctional Molecules. Acs Chemical Biology. PMID 37382390 DOI: 10.1021/acschembio.3c00191  0.575
2023 Hommen P, Hwang J, Huang F, Borgelt L, Hohnen L, Wu P. Chromenopyrazole-peptide conjugates as small-molecule based inhibitors disrupting the protein-RNA interaction of LIN28-let-7. Chembiochem : a European Journal of Chemical Biology. e202300376. PMID 37224100 DOI: 10.1002/cbic.202300376  0.785
2023 Hwang J, Haacke N, Borgelt L, Qiu X, Gasper R, Wu P. Rational design and evaluation of 2-((pyrrol-2-yl)methylene)thiophen-4-ones as RNase L inhibitors. European Journal of Medicinal Chemistry. 256: 115439. PMID 37201427 DOI: 10.1016/j.ejmech.2023.115439  0.832
2023 Borgelt L, Huang F, Hohnen L, Qiu X, Goebel GL, Hommen P, Wu P. Spirocyclic Chromenopyrazole Inhibitors Disrupting the Interaction between the RNA-binding protein LIN28 and Let-7. Chembiochem : a European Journal of Chemical Biology. e202300168. PMID 37129525 DOI: 10.1002/cbic.202300168  0.818
2022 Borgelt L, Haacke N, Lampe P, Qiu X, Gasper R, Schiller D, Hwang J, Sievers S, Wu P. Small-molecule screening of ribonuclease L binders for RNA degradation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 154: 113589. PMID 36029542 DOI: 10.1016/j.biopha.2022.113589  0.77
2022 Hwang J, Qiu X, Borgelt L, Haacke N, Kanis L, Petroulia S, Gasper R, Schiller D, Lampe P, Sievers S, Imig J, Wu P. Synthesis and evaluation of RNase L-binding 2-aminothiophenes as anticancer agents. Bioorganic & Medicinal Chemistry. 58: 116653. PMID 35152173 DOI: 10.1016/j.bmc.2022.116653  0.647
2021 Goebel GL, Hohnen L, Borgelt L, Hommen P, Qiu X, Lightfoot H, Wu P. Small molecules with tetrahydroquinoline-containing Povarov scaffolds as inhibitors disrupting the Protein-RNA interaction of LIN28-let-7. European Journal of Medicinal Chemistry. 228: 114014. PMID 34883291 DOI: 10.1016/j.ejmech.2021.114014  0.709
2021 Borgelt L, Li F, Hommen P, Lampe P, Hwang J, Goebel GL, Sievers S, Wu P. Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and . Acs Medicinal Chemistry Letters. 12: 893-898. PMID 34136077 DOI: 10.1021/acsmedchemlett.0c00546  0.83
2020 Hwang J, Borgelt L, Wu P. Multicomponent Petasis Reaction for the Synthesis of Functionalized 2-Aminothiophenes and Thienodiazepines. Acs Combinatorial Science. PMID 32985878 DOI: 10.1021/acscombsci.0c00173  0.696
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