Sebastian Fica - Publications

Affiliations: 
University of Chicago, Chicago, IL 

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Aupič J, Borišek J, Fica SM, Galej WP, Magistrato A. Monovalent metal ion binding promotes the first transesterification reaction in the spliceosome. Nature Communications. 14: 8482. PMID 38123540 DOI: 10.1038/s41467-023-44174-2  0.418
2023 Parker MT, Fica SM, Barton GJ, Simpson GG. Inter-species association mapping links splice site evolution to METTL16 and SNRNP27K. Elife. 12. PMID 37787376 DOI: 10.7554/eLife.91997  0.314
2022 Parker MT, Soanes BK, Kusakina J, Larrieu A, Knop K, Joy N, Breidenbach F, Sherwood AV, Barton GJ, Fica SM, Davies BH, Simpson GG. mA modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site. Elife. 11. PMID 36409063 DOI: 10.7554/eLife.78808  0.449
2021 Strittmatter LM, Capitanchik C, Newman AJ, Hallegger M, Norman CM, Fica SM, Oubridge C, Luscombe NM, Ule J, Nagai K. psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation. Nature Communications. 12: 1488. PMID 33674615 DOI: 10.1038/s41467-021-21745-9  0.435
2020 Fica SM. Cryo-EM snapshots of the human spliceosome reveal structural adaptions for splicing regulation. Current Opinion in Structural Biology. 65: 139-148. PMID 32717639 DOI: 10.1016/j.sbi.2020.06.018  0.373
2019 Fica SM, Oubridge C, Wilkinson ME, Newman AJ, Nagai K. A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science (New York, N.Y.). PMID 30705154 DOI: 10.1126/science.aaw5569  0.438
2017 Wilkinson ME, Fica SM, Galej WP, Norman CM, Newman AJ, Nagai K. Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection. Science (New York, N.Y.). PMID 29146871 DOI: 10.1126/science.aar3729  0.388
2017 Fica SM, Nagai K. Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine. Nature Structural & Molecular Biology. 24: 791-799. PMID 28981077 DOI: 10.1038/nsmb.3463  0.307
2017 Fica SM, Oubridge C, Galej WP, Wilkinson ME, Bai XC, Newman AJ, Nagai K. Structure of a spliceosome remodelled for exon ligation. Nature. PMID 28076345 DOI: 10.1038/nature21078  0.471
2016 Galej WP, Wilkinson ME, Fica SM, Oubridge C, Newman AJ, Nagai K. Cryo-EM structure of the spliceosome immediately after branching. Nature. PMID 27459055 DOI: 10.1038/nature19316  0.444
2016 Nguyen TH, Galej WP, Fica SM, Lin PC, Newman AJ, Nagai K. CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast. Current Opinion in Structural Biology. 36: 48-57. PMID 26803803 DOI: 10.1016/j.sbi.2015.12.005  0.443
2013 Fica SM, Tuttle N, Novak T, Li NS, Lu J, Koodathingal P, Dai Q, Staley JP, Piccirilli JA. RNA catalyses nuclear pre-mRNA splicing. Nature. 503: 229-34. PMID 24196718 DOI: 10.1038/Nature12734  0.712
2013 Schellenberg MJ, Wu T, Ritchie DB, Fica S, Staley JP, Atta KA, LaPointe P, MacMillan AM. A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nature Structural & Molecular Biology. 20: 728-34. PMID 23686287 DOI: 10.1038/Nsmb.2556  0.711
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