Jia-huai Wang, Ph.D. - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Finci LI, Zhang J, Sun X, Smock RG, Meijers R, Zhang Y, Xiao J, Wang JH. Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC. Protein & Cell. PMID 28664251 DOI: 10.1007/S13238-017-0439-X  0.716
2017 Xu S, Wang J, Wang JH, Springer TA. Distinct recognition of complement iC3b by integrins αXβ2 and αMβ2. Proceedings of the National Academy of Sciences of the United States of America. PMID 28292891 DOI: 10.1073/Pnas.1620881114  0.465
2016 Liu H, Li W, Yu X, Gao F, Duan Z, Ma X, Tan S, Yuan Y, Liu L, Wang J, Zhou X, Yang Y. EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis. Oncotarget. PMID 27472460 DOI: 10.18632/oncotarget.10841  0.304
2016 Yang Y, Liu Y, He JC, Wang JM, Schemmer P, Ma CQ, Qian YW, Yao W, Zhang J, Qi WP, Fu Y, Feng W, Yang T. 14-3-3ζ and aPKC-ι synergistically facilitate epithelial-mesenchymal transition of cholangiocarcinoma via GSK-3β/snail signaling pathway. Oncotarget. PMID 27409422 DOI: 10.18632/oncotarget.10483  0.302
2016 Wang J, Yang Y, Li Y, Wang Y. A Computational study exploring the interaction mechanism of benzimidazole derivatives as potent cattle bovine viral diarrhea virus inhibitors. Journal of Agricultural and Food Chemistry. PMID 27355875 DOI: 10.1021/acs.jafc.6b01067  0.308
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Wang J, ... Wang J, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.414
2016 Yang Y, Li Y, Pan Y, Wang J, Lin F, Wang C, Zhang S, Yang L. Computational Analysis of Structure-Based Interactions for Novel H₁-Antihistamines. International Journal of Molecular Sciences. 17. PMID 26797608 DOI: 10.3390/ijms17010129  0.33
2015 Lian Y, Ding J, Zhang Z, Shi Y, Zhu Y, Li J, Peng P, Wang J, Fan Y, De W, Wang K. The long noncoding RNA HOXA transcript at the distal tip promotes colorectal cancer growth partially via silencing of p21 expression. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 26678886 DOI: 10.1007/s13277-015-4617-2  0.32
2015 Wang JD, Cao YL, Li Q, Yang YP, Jin M, Chen D, Wang F, Wang GH, Qin ZH, Hu LF, Liu CF. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 11: 2057-2073. PMID 26649942 DOI: 10.1080/15548627.2015.1100930  0.304
2015 Wang J, Hao J, Bai D, Gu Q, Han W, Wang L, Tan Y, Li X, Xue K, Han P, Liu Z, Jia Y, Wu J, Liu L, Wang L, et al. Generation of clinical-grade human induced pluripotent stem cells in Xeno-free conditions. Stem Cell Research & Therapy. 6: 223. PMID 26564165 DOI: 10.1186/S13287-015-0206-Y  0.349
2015 Tu X, Kuang Z, Gong X, Shi Y, Yu L, Shi H, Wang J, Sun Z. The Influence of LepR Tyrosine Site Mutations on Mouse Ovary Development and Related Gene Expression Changes. Plos One. 10: e0141800. PMID 26529315 DOI: 10.1371/journal.pone.0141800  0.312
2015 Chen X, Zhao C, Li X, Wang T, Li Y, Cao C, Ding Y, Dong M, Finci L, Wang JH, Li X, Liu L. Terazosin activates Pgk1 and Hsp90 to promote stress resistance. Nature Chemical Biology. 11: 19-25. PMID 25383758 DOI: 10.1038/nchembio.1657  0.718
2014 Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HD, Svergun DI, Zhang Y, Wang JH, Meijers R. The crystal structure of netrin-1 in complex with DCC reveals the bifunctionality of netrin-1 as a guidance cue. Neuron. 83: 839-49. PMID 25123307 DOI: 10.1016/J.Neuron.2014.07.010  0.724
2013 Yu Y, Zhu J, Huang PS, Wang JH, Pullen N, Springer TA. Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loop. The Journal of Biological Chemistry. 288: 6284-94. PMID 23297416 DOI: 10.1074/Jbc.M112.413153  0.48
2012 Schürpf T, Chen Q, Liu JH, Wang R, Springer TA, Wang JH. The RGD finger of Del-1 is a unique structural feature critical for integrin binding. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3412-20. PMID 22601780 DOI: 10.1096/Fj.11-202036  0.481
2009 Zhang H, Liu JH, Yang W, Springer T, Shimaoka M, Wang JH. Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1. Proceedings of the National Academy of Sciences of the United States of America. 106: 18345-50. PMID 19805116 DOI: 10.1073/Pnas.0909301106  0.468
2008 Zhang H, Casasnovas JM, Jin M, Liu JH, Gahmberg CG, Springer TA, Wang JH. An unusual allosteric mobility of the C-terminal helix of a high-affinity alphaL integrin I domain variant bound to ICAM-5. Molecular Cell. 31: 432-7. PMID 18691975 DOI: 10.1016/J.Molcel.2008.06.022  0.472
2008 Tan K, Duquette M, Liu JH, Shanmugasundaram K, Joachimiak A, Gallagher JT, Rigby AC, Wang JH, Lawler J. Heparin-induced cis- and trans-dimerization modes of the thrombospondin-1 N-terminal domain. The Journal of Biological Chemistry. 283: 3932-41. PMID 18065761 DOI: 10.1074/Jbc.M705203200  0.306
2005 Song G, Yang Y, Liu JH, Casasnovas JM, Shimaoka M, Springer TA, Wang JH. An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2. Proceedings of the National Academy of Sciences of the United States of America. 102: 3366-71. PMID 15728350 DOI: 10.1073/Pnas.0500200102  0.554
2005 Meijers R, Lai CC, Yang Y, Liu JH, Zhong W, Wang JH, Reinherz EL. Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance. Journal of Molecular Biology. 345: 1099-110. PMID 15644207 DOI: 10.1016/J.Jmb.2004.11.023  0.386
2004 Springer TA, Wang JH. The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion. Advances in Protein Chemistry. 68: 29-63. PMID 15500858 DOI: 10.1016/S0065-3233(04)68002-8  0.474
2004 Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 432: 59-67. PMID 15378069 DOI: 10.1038/Nature02976  0.681
2004 Yang Y, Jun CD, Liu JH, Zhang R, Joachimiak A, Springer TA, Wang JH. Structural basis for dimerization of ICAM-1 on the cell surface. Molecular Cell. 14: 269-76. PMID 15099525 DOI: 10.1016/S1097-2765(04)00204-7  0.536
2004 Springer TA, Takagi J, Coller BS, Wang J, Xiao T. Crystal Structure of the Integrin αIIBβ3 Headpiece at 2.7–3.1 Å: Structure, Mechanisms of Activation and Ligand Binding, Inhibition by Eptifibatide, Tirofiban, and mAb 10E5, and Structure of the HPA-1 Alloantigen Epitope. Blood. 104: 327-327. DOI: 10.1182/Blood.V104.11.327.327  0.467
2003 Takagi J, Yang Y, Liu JH, Wang JH, Springer TA. Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface. Nature. 424: 969-74. PMID 12931195 DOI: 10.1038/Nature01873  0.552
2003 Sasada T, Yang Y, Lai CC, Touma M, Clayton LK, Liu JH, Parisini E, Wang JH, Reinherz EL. Disparate peptide-dependent thymic selection outcomes in beta2M-deficient mice versus TAP-1-deficient mice: implications for repertoire formation. European Journal of Immunology. 33: 368-80. PMID 12645934 DOI: 10.1002/Immu.200310011  0.364
2003 Shimaoka M, Xiao T, Liu JH, Yang Y, Dong Y, Jun CD, McCormack A, Zhang R, Joachimiak A, Takagi J, Wang JH, Springer TA. Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation. Cell. 112: 99-111. PMID 12526797 DOI: 10.1016/S0092-8674(02)01257-6  0.688
2002 Jing H, Takagi J, Liu JH, Lindgren S, Zhang RG, Joachimiak A, Wang JH, Springer TA. Archaeal surface layer proteins contain beta propeller, PKD, and beta helix domains and are related to metazoan cell surface proteins. Structure (London, England : 1993). 10: 1453-64. PMID 12377130 DOI: 10.1016/S0969-2126(02)00840-7  0.456
1999 Green N, Rosebrook J, Cochran N, Tan K, Wang JH, Springer TA, Briskin MJ. Mutational analysis of MAdCAM-1/alpha4beta7 interactions reveals significant binding determinants in both the first and second immunuglobulin domains. Cell Adhesion and Communication. 7: 167-81. PMID 10626902 DOI: 10.3109/15419069909010800  0.483
1998 Wang J, Springer TA. Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses. Immunological Reviews. 163: 197-215. PMID 9700512 DOI: 10.1111/J.1600-065X.1998.Tb01198.X  0.486
1998 Tan K, Casasnovas JM, Liu JH, Briskin MJ, Springer TA, Wang JH. The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition. Structure (London, England : 1993). 6: 793-801. PMID 9655832 DOI: 10.1016/S0969-2126(98)00080-X  0.477
1998 Casasnovas JM, Stehle T, Liu JH, Wang JH, Springer TA. A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1. Proceedings of the National Academy of Sciences of the United States of America. 95: 4134-9. PMID 9539702 DOI: 10.1073/Pnas.95.8.4134  0.47
1998 Wang J, Lim K, Smolyar A, Teng M, Liu J, Tse AG, Liu J, Hussey RE, Chishti Y, Thomson CT, Sweet RM, Nathenson SG, Chang HC, Sacchettini JC, Reinherz EL. Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. The Embo Journal. 17: 10-26. PMID 9427737 DOI: 10.1093/Emboj/17.1.10  0.317
1997 Casasnovas JM, Springer TA, Liu JH, Harrison SC, Wang JH. Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface. Nature. 387: 312-5. PMID 9153399 DOI: 10.1038/387312A0  0.485
1995 Wang JH, Blake Pepinsky R, Stehle T, Liu JH, Karpusas M, Browning B, Osborn L. The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): A cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-α4 integrin interaction Proceedings of the National Academy of Sciences of the United States of America. 92: 5714-5718. PMID 7539925 DOI: 10.1073/Pnas.92.12.5714  0.32
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