Matteo Borgini - Related publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Chemistry
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Yan J, Xu Y, Jin X, Zhang Q, Ouyang F, Han L, Zhan M, Li X, Liang B, Huang X. Structure modification and biological evaluation of indole-chalcone derivatives as anti-tumor agents through dual targeting tubulin and TrxR. European Journal of Medicinal Chemistry. 227: 113897. PMID 34649064 DOI: 10.1016/j.ejmech.2021.113897   
2021 Sherbiny FF, Bayoumi AH, El-Morsy AM, Sobhy M, Hagras M. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers. Bioorganic Chemistry. 116: 105325. PMID 34507234 DOI: 10.1016/j.bioorg.2021.105325   
2021 Tavares FM, Gomes AC, Assunção EM, de Medeiros JLS, Scotti MT, Scotti L, Ishiki HM. Virtual Screening and Molecular Docking: Discovering Novel c-KIT Inhibitors. Current Medicinal Chemistry. PMID 34525909 DOI: 10.2174/0929867328666210915102920   
2021 El Azab IH, Saied EM, Osman AA, Mehana AE, Saad HA, Elkanzi NA. Novel -bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis, and studies. Future Medicinal Chemistry. PMID 34427113 DOI: 10.4155/fmc-2021-0066   
2021 Pérez-Villanueva J, Matadamas-Martínez F, Yépez-Mulia L, Pérez-Koldenkova V, Leyte-Lugo M, Rodríguez-Villar K, Cortés-Benítez F, Macías-Jiménez AP, González-Sánchez I, Romero-Velásquez A, Palacios-Espinosa JF, Soria-Arteche O. Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2-indazole Hybrids. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451912 DOI: 10.3390/ph14080815   
2021 Han X, Song N, Saidahmatov A, Wang P, Wang Y, Hu X, Kan W, Zhu W, Gao L, Zeng M, Wang Y, Li C, Li J, Liu H, Zhou Y, et al. Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia. Journal of Medicinal Chemistry. PMID 34477384 DOI: 10.1021/acs.jmedchem.1c01148   
2021 Emam AM, Dahal A, Singh SS, Tosso RD, Ibrahim SM, El-Sadek M, Jois SD, Enriz RD, Kothayer H. Quinazoline-tethered hydrazone: A versatile scaffold toward dual anti-TB and EGFR inhibition activities in NSCLC. Archiv Der Pharmazie. e2100281. PMID 34585758 DOI: 10.1002/ardp.202100281   
2021 Elhady SS, Abdelhameed RFA, Zekry SH, Ibrahim AK, Habib ES, Darwish KM, Hazem RM, Mohammad KA, Hassanean HA, Ahmed SA. VEGFR-Mediated Cytotoxic Activity of Isolated Metabolites: A Biological Evaluation and In Silico Study. Life (Basel, Switzerland). 11. PMID 34440504 DOI: 10.3390/life11080759   
2021 Pellissier L, Koval A, Marcourt L, Ferreira Queiroz E, Lecoultre N, Leoni S, Quiros-Guerrero LM, Barthélémy M, Duivelshof BL, Guillarme D, Tardy S, Eparvier V, Perron K, Chave J, Stien D, et al. Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of . Frontiers in Chemistry. 9: 664489. PMID 34458231 DOI: 10.3389/fchem.2021.664489   
2021 Gaber AA, El-Morsy AM, Sherbiny FF, Bayoumi AH, El-Gamal KM, El-Adl K, Al-Karmalawy AA, Ezz Eldin RR, Saleh MA, Abulkhair HS. Pharmacophore-linked pyrazolo[3,4-d]pyrimidines as EGFR-TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies. Archiv Der Pharmazie. e2100258. PMID 34467546 DOI: 10.1002/ardp.202100258   
2021 Theofylaktou D, Takan I, Karakülah G, Biz GM, Zanni V, Pavlopoulou A, Georgakilas AG. Mining Natural Products with Anticancer Biological Activity through a Systems Biology Approach. Oxidative Medicine and Cellular Longevity. 2021: 9993518. PMID 34422220 DOI: 10.1155/2021/9993518   
2021 Mbaoji FN, Nweze JA, Yang L, Huang Y, Huang S, Onwuka AM, Peter IE, Mbaoji CC, Jiang M, Zhang Y, Pan L, Yang D. Novel Marine Secondary Metabolites Worthy of Development as Anticancer Agents: A Review. Molecules (Basel, Switzerland). 26. PMID 34641312 DOI: 10.3390/molecules26195769   
2021 KalantarMotamedi Y, Choi RJ, Koh SB, Bramhall JL, Fan TP, Bender A. Prediction and identification of synergistic compound combinations against pancreatic cancer cells. Iscience. 24: 103080. PMID 34585118 DOI: 10.1016/j.isci.2021.103080   
2021 Islam MK, Baek AR, Sung B, Yang BW, Choi G, Park HJ, Kim YH, Kim M, Ha S, Lee GH, Kim HK, Chang Y. Synthesis, Characterization, and Anticancer Activity of Benzothiazole Aniline Derivatives and Their Platinum (II) Complexes as New Chemotherapy Agents. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451928 DOI: 10.3390/ph14080832   
2021 Medina JR, Tian X, Li WH, Suarez D, Mack JF, LaFrance L, Martyr C, Brackley J, Di Marco C, Rivero R, Heerding DA, McHugh C, Minthorn E, Bhaskar A, Rubin J, et al. Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce -MYC Protein Levels in Cells. Journal of Medicinal Chemistry. PMID 34669409 DOI: 10.1021/acs.jmedchem.1c01416   
2021 Butala S, Suvarna V, Mallya R, Khan T. An insight into cytotoxic activity of flavonoids and sesquiterpenoids from selected plants of Asteraceae species. Chemical Biology & Drug Design. PMID 34626448 DOI: 10.1111/cbdd.13970   
2021 Saha T, Mondal J, Khiste S, Lusic H, Hu ZW, Jayabalan R, Hodgetts KJ, Jang H, Sengupta S, Eunice Lee S, Park Y, Lee LP, Goldman A. Nanotherapeutic approaches to overcome distinct drug resistance barriers in models of breast cancer. Nanophotonics. 10: 3063-3073. PMID 34589378 DOI: 10.1515/nanoph-2021-0142   
2021 Goehringer N, Biersack B, Peng Y, Schobert R, Herling M, Ma A, Nitzsche B, Höpfner M. Anticancer Activity and Mechanisms of Action of New Chimeric EGFR/HDAC-Inhibitors. International Journal of Molecular Sciences. 22. PMID 34445133 DOI: 10.3390/ijms22168432   
2021 Yuan P, Gu X, Ni X, Qi Y, Shao X, Xu X, Liu J, Qian X. Non-alkylator anti-glioblastoma agents induced cell cycle G2/M arrest and apoptosis:Design, In silico physicochemical and SAR Studies of 2-Aminoquinoline-3-carboxamides. Bioorganic & Medicinal Chemistry Letters. 128371. PMID 34534673 DOI: 10.1016/j.bmcl.2021.128371   
2021 Cao Z, Yang F, Wang J, Gu Z, Lin S, Wang P, An J, Liu T, Li Y, Li Y, Lin H, Zhao Y, He B. Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent Kinase and Histone Deacetylase for Treating Cancer. Journal of Medicinal Chemistry. PMID 34624191 DOI: 10.1021/acs.jmedchem.1c01311   
2021 Balbuena-Rebolledo I, Padilla-Martínez II, Rosales-Hernández MC, Bello M. Repurposing FDA Drug Compounds against Breast Cancer by Targeting EGFR/HER2. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451888 DOI: 10.3390/ph14080791   
2021 Onder FC, Durdagi S, Kahraman N, Uslu TN, Kandemir H, Atici EB, Ozpolat B, Ay M. Novel inhibitors of eukaryotic elongation factor 2 kinase: In silico, synthesis and in vitro studies. Bioorganic Chemistry. 116: 105296. PMID 34488125 DOI: 10.1016/j.bioorg.2021.105296   
2021 Yao Q, Gao S, Wu C, Lin T, Gao Y. Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance. Biomaterials. 277: 121119. PMID 34492583 DOI: 10.1016/j.biomaterials.2021.121119   
2021 Delbart DI, Giri GF, Cammarata A, Bareño LA, Amigo NL, Bechis A, Suarez AG, Spanevello RÁ, Todaro LB, Urtreger AJ. Antineoplastic activity of products derived from cellulose-containing materials: levoglucosenone and structurally-related derivatives as new alternatives for breast cancer treatment. Investigational New Drugs. PMID 34478029 DOI: 10.1007/s10637-021-01167-6   
2021 Yang BJ, Wang J, Zeng ZQ, Yang X, Huang AY, Hao XJ, Ding X, Li SL. Sesquiterpene lactones from L. and their activity in inducing protective autophagy. Natural Product Research. 1-4. PMID 34498970 DOI: 10.1080/14786419.2021.1955881   
2021 Xie Q, Chen Y, Tan H, Liu B, Zheng LL, Mu Y. Targeting Autophagy with Natural Compounds in Cancer: A Renewed Perspective from Molecular Mechanisms to Targeted Therapy. Frontiers in Pharmacology. 12: 748149. PMID 34512368 DOI: 10.3389/fphar.2021.748149   
2021 Xie SC, Metcalfe RD, Mizutani H, Puhalovich T, Hanssen E, Morton CJ, Du Y, Dogovski C, Huang SC, Ciavarri J, Hales P, Griffin RJ, Cohen LH, Chuang BC, Wittlin S, et al. Design of proteasome inhibitors with oral efficacy in vivo against and selectivity over the human proteasome. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34548400 DOI: 10.1073/pnas.2107213118   
2021 Lu B, Liu D, Gui B, Gou J, Dong H, Hu Q, Feng J, Mao Y, Shen X, Wang S, Zhang C, Shen R, Yan Y, Chen L, Wang H, et al. Discovery of 2-(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity. Journal of Medicinal Chemistry. PMID 34643383 DOI: 10.1021/acs.jmedchem.1c00828   
2021 Tuli HS, Joshi R, Aggarwal D, Kaur G, Kaur J, Kumar M, Parashar NC, Khan MA, Sak K. Molecular mechanisms underlying chemopreventive potential of butein: Current trends and future perspectives. Chemico-Biological Interactions. 350: 109699. PMID 34648814 DOI: 10.1016/j.cbi.2021.109699   
2021 Sharma B, Singh VJ, Chawla PA. Epidermal growth factor receptor inhibitors as potential anticancer agents: An update of recent progress. Bioorganic Chemistry. 116: 105393. PMID 34628226 DOI: 10.1016/j.bioorg.2021.105393   
2021 Zheng Q, Xu XB, Jin H, Zhang W, Rao GW. Synthesis and anti-proliferation activity evaluation of novel 2-chloroquinazoline as potential EGFR-TK inhibitors. Chemistry & Biodiversity. PMID 34510749 DOI: 10.1002/cbdv.202100478   
2021 Nelson GL, Ronayne CT, Solano LN, Jonnalagadda SK, Jonnalagadda S, Schumacher TJ, Gardner ZS, Palle H, Mani C, Rumbley J, Mereddy VR. Synthesis and biological evaluation of N, N-dialkylcarboxy coumarin-NO donor conjugates as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters. 128411. PMID 34626786 DOI: 10.1016/j.bmcl.2021.128411   
2021 Liu KL, Li XY, Wang DP, Xue WH, Qian XH, Li YH, Lin QQ, Li S, Meng FH. Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation. Journal of Medicinal Chemistry. PMID 34473510 DOI: 10.1021/acs.jmedchem.1c00582   
2021 He M, Yin WQ, Sun HF, Ding YW, Xu S, Sun H, Wang JM, Yu P, Qin HJ, Chen MH. Four new fatty acid derivatives from sp. T24, an endophytic fungus isolated from . Journal of Asian Natural Products Research. 1-14. PMID 34622714 DOI: 10.1080/10286020.2021.1962309   
2021 Yue K, Hou X, Jia G, Zhang L, Zhang J, Tan L, Wang X, Zhang Z, Li P, Xu W, Li X, Jiang Y. Design, synthesis and biological evaluation of hybrid of ubenimex-fluorouracil for hepatocellular carcinoma therapy. Bioorganic Chemistry. 116: 105343. PMID 34544027 DOI: 10.1016/j.bioorg.2021.105343   
2021 Manaithiya A, Alam O, Sharma V, Naim MJ, Mittal S, Azam F, Husain A, Sheikh AA, Imran M, Khan IA. Current status of novel pyridine fused derivatives as anticancer agents: An insight into future perspectives and structure activity relationship (SAR). Current Topics in Medicinal Chemistry. PMID 34530713 DOI: 10.2174/1568026621666210916171015   
2021 Lu M, Zhang H, Li D, Childers M, Pu Q, Palte RL, Gathiaka S, Lyons TW, Palani A, Fan PW, Spacciapoli P, Miller JR, Cho H, Cheng M, Chakravarthy K, et al. Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology. Acs Medicinal Chemistry Letters. 12: 1380-1388. PMID 34527178 DOI: 10.1021/acsmedchemlett.1c00195   
2021 Poonan P, Agoni C, Ibrahim MAA, Soliman MES. Glioma-Targeted Therapeutics: Computer-Aided Drug Design Prospective. The Protein Journal. 40: 601-655. PMID 34590194 DOI: 10.1007/s10930-021-10021-w   
2021 Ii H, Nohara Y, Yoshiya T, Masuda S, Tsuda S, Oishi S, Friedman J, Kawabe T, Nakata S. Identification of U83836E as a γ-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth. Biochemical and Biophysical Research Communications. 549: 128-134. PMID 33676180 DOI: 10.1016/j.bbrc.2021.02.103   
2021 Yesilkanal AE, Johnson GL, Ramos AF, Rosner MR. New strategies for targeting kinase networks in cancer. The Journal of Biological Chemistry. 101128. PMID 34461089 DOI: 10.1016/j.jbc.2021.101128   
2021 Zhang Z, Zhang Q, Zhang H, Jiao M, Guo Z, Peng X, Fu L, Li J. Discovery of quinazolinyl-containing benzamides derivatives as novel HDAC1 inhibitors with in vitro and in vivo antitumor activities. Bioorganic Chemistry. 117: 105407. PMID 34653945 DOI: 10.1016/j.bioorg.2021.105407   
2021 Pathak A, Pandey V, Raj Pokharel Y, Devaraji V, Ali A, Haider K, Saad S, Dewangan RP, Siddiqui N, Shahar Yar M. Pharmacophore based drug design and synthesis of oxindole bearing hybrid as anticancer agents. Bioorganic Chemistry. 116: 105358. PMID 34544029 DOI: 10.1016/j.bioorg.2021.105358   
2021 Xuan GS, Zhan JH, Zhang AM, Li W, Zheng K. Inhibition of carbonic anhydrase II by sulfonamide derivatives. Die Pharmazie. 76: 412-415. PMID 34481530 DOI: 10.1691/ph.2021.1590   
2021 Wang B, Feng W, Wang J, Dong Y, Liu Y, Yao Y, Zhang J, Shi W, Liu L, Zhang H, He X, Chang X, Wang X, Xu H, Liu F, et al. Discovery of potent and selective Bcl-2 inhibitors with acyl sulfonamide skeleton. Bioorganic & Medicinal Chemistry. 47: 116350. PMID 34536651 DOI: 10.1016/j.bmc.2021.116350   
2021 Yu KH, Hung CC, Wu TS, Chen CF, Wu IT, Kuo PC, Lam SH, Hung HY. Chemoreversal Agents from Taiwanofungus Genus and Their More Potent Methyl Derivatives Targeting Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation. Pharmaceuticals (Basel, Switzerland). 14. PMID 34577615 DOI: 10.3390/ph14090916   
2021 Cooper E, Choi PJ, Schweder P, Mee E, Turner C, Faull R, Denny WA, Dragunow M, I-H Park T, Jose J. Cytoprotective agent troxipide-cyanine dye conjugate with cytotoxic and antiproliferative activity in patient-derived glioblastoma cell lines. Bioorganic & Medicinal Chemistry Letters. 128336. PMID 34438012 DOI: 10.1016/j.bmcl.2021.128336   
2021 Ali A, Ali A, Tahir A, Bakht MA, Salahuddin, Ahsan MJ. Molecular Engineering of Curcumin, an Active Constituent of L. (Turmeric) of the Family with Improved Antiproliferative Activity. Plants (Basel, Switzerland). 10. PMID 34451604 DOI: 10.3390/plants10081559   
2021 Bozzer S, Bo MD, Toffoli G, Macor P, Capolla S. Nanoparticles-Based Oligonucleotides Delivery in Cancer: Role of Zebrafish as Animal Model. Pharmaceutics. 13. PMID 34452067 DOI: 10.3390/pharmaceutics13081106   
2021 Finlay MRV, Barton P, Bickerton S, Bista M, Colclough N, Cross DAE, Evans L, Floc'h N, Gregson C, Guérot CM, Hargreaves D, Kang X, Lenz EM, Li X, Liu Y, et al. Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance. Journal of Medicinal Chemistry. PMID 34491761 DOI: 10.1021/acs.jmedchem.1c01055   
2021 Zhang D, Hu Y, Hao Z, Zhang Y, Luo S, Dang X, Sun R, Duan S, Lv D, Jiang F, Fu L. Design, synthesis and antitumor activities of thiazole-containing mitochondrial targeting agents. Bioorganic Chemistry. 115: 105271. PMID 34426155 DOI: 10.1016/j.bioorg.2021.105271