| Year |
Citation |
Score |
| 2020 |
Koh WX, Coppo L, Holmgren A, Kong JW, Leong WK. Inhibition of Thioredoxin Reductase by Triosmium Carbonyl Clusters. Chemical Research in Toxicology. PMID 32786549 DOI: 10.1021/Acs.Chemrestox.0C00214 |
0.355 |
|
| 2020 |
Cheng P, Liu H, Li Y, Pi P, Jiang Y, Zang S, Li X, Fu A, Ren X, Xu J, Holmgren A, Lu J. Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury. Biochemical Pharmacology. 113873. PMID 32092292 DOI: 10.1016/J.Bcp.2020.113873 |
0.32 |
|
| 2020 |
Ren X, Zou L, Holmgren A. Targeting Bacterial Antioxidant Systems for Antibiotics Development. Current Medicinal Chemistry. 27: 1922-1939. PMID 31589114 DOI: 10.2174/0929867326666191007163654 |
0.308 |
|
| 2019 |
Li J, Zuo X, Cheng P, Ren X, Sun S, Xu J, Holmgren A, Lu J. The production of reactive oxygen species enhanced with the reduction of menadione by active thioredoxin reductase. Metallomics : Integrated Biometal Science. PMID 31359011 DOI: 10.1039/C9Mt00133F |
0.364 |
|
| 2019 |
Sengupta R, Coppo L, Mishra P, Holmgren A. Glutathione-Glutaredoxin as an efficient electron donor system for mammalian p53R2-R1- dependent ribonucleotide reductase. The Journal of Biological Chemistry. PMID 31266802 DOI: 10.1074/Jbc.Ra119.008752 |
0.324 |
|
| 2019 |
Ren X, Sengupta R, Lu J, Lundberg JO, Holmgren A. Characterization of mammalian glutaredoxin isoforms as S-denitrosylases. Febs Letters. PMID 31125428 DOI: 10.1002/1873-3468.13454 |
0.351 |
|
| 2019 |
Ren X, Santhosh S, Coppo L, Ogata F, Lu J, Holmgren A. The combination of ascorbate and menadione causes cancer cell death by oxidative stress and replicative stress. Free Radical Biology & Medicine. PMID 30703479 DOI: 10.1016/J.Freeradbiomed.2019.01.037 |
0.367 |
|
| 2019 |
Coppo L, Ogata FT, Santhosh SM, Sventelius T, Holmgren A. Enzymatic glutaredoxin-dependent method to determine glutathione and protein S-glutathionylation using fluorescent eosin-glutathione. Analytical Biochemistry. 568: 24-30. PMID 30597126 DOI: 10.1016/J.Ab.2018.12.021 |
0.344 |
|
| 2018 |
Haffo L, Lu J, Bykov VJN, Martin SS, Ren X, Coppo L, Wiman KG, Holmgren A. Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246. Scientific Reports. 8: 12671. PMID 30140002 DOI: 10.1038/S41598-018-31048-7 |
0.34 |
|
| 2018 |
Ren X, Zou L, Lu J, Holmgren A. Selenocysteine in mammalian thioredoxin reductase and application of ebselen as a therapeutic. Free Radical Biology & Medicine. PMID 29807162 DOI: 10.1016/J.Freeradbiomed.2018.05.081 |
0.397 |
|
| 2018 |
Gopalakrishna R, Gundimeda U, Zhou S, Helena B, Holmgren A. Redox regulation of protein kinase C by selenometabolites and selenoprotein thioredoxin reductase limits cancer prevention by selenium. Free Radical Biology & Medicine. PMID 29775743 DOI: 10.1016/J.Freeradbiomed.2018.05.062 |
0.326 |
|
| 2018 |
Bräutigam L, Zhang J, Dreij K, Spahiu L, Holmgren A, Abe H, Tew KD, Townsend DM, Kelner MJ, Morgenstern R, Johansson K. MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. Redox Biology. 17: 171-179. PMID 29702404 DOI: 10.1016/J.Redox.2018.04.013 |
0.303 |
|
| 2018 |
Miller CG, Holmgren A, Arnér ESJ, Schmidt EE. NADPH-dependent and -independent Disulfide Reductase Systems. Free Radical Biology & Medicine. PMID 29609022 DOI: 10.1016/J.Freeradbiomed.2018.03.051 |
0.325 |
|
| 2018 |
Ouyang Y, Peng Y, Li J, Holmgren A, Lu J. Modulation of thiol-dependent redox system by metal ions via thioredoxin and glutaredoxin systems. Metallomics : Integrated Biometal Science. PMID 29410996 DOI: 10.1039/C7Mt00327G |
0.308 |
|
| 2017 |
Prigge JR, Coppo L, Martin SS, Ogata F, Miller CG, Bruschwein MD, Orlicky DJ, Shearn CT, Kundert JA, Lytchier J, Herr AE, Mattsson Å, Taylor MP, Gustafsson TN, Arnér ESJ, ... Holmgren A, et al. Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase. Cell Reports. 19: 2771-2781. PMID 28658624 DOI: 10.1016/J.Celrep.2017.06.019 |
0.341 |
|
| 2017 |
Lepka K, Volbracht K, Bill E, Schneider R, Rios N, Hildebrandt T, Ingwersen J, Prozorovski T, Lillig CH, van Horssen J, Steinman L, Hartung HP, Radi R, Holmgren A, Aktas O, et al. Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia. Glia. PMID 28618115 DOI: 10.1002/Glia.23178 |
0.332 |
|
| 2017 |
Branco V, Coppo L, Solá S, Lu J, Rodrigues CMP, Holmgren A, Carvalho C. Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury. Redox Biology. 13: 278-287. PMID 28600984 DOI: 10.1016/J.Redox.2017.05.024 |
0.346 |
|
| 2017 |
Ren X, Zou L, Zhang X, Branco V, Wang J, Carvalho C, Holmgren A, Lu J. Redox Signaling Mediated by the Thioredoxin and Glutathione Systems in the Central Nervous System. Antioxidants & Redox Signaling. PMID 28443683 DOI: 10.1089/Ars.2016.6925 |
0.316 |
|
| 2016 |
Owings JP, McNair NN, Mui YF, Gustafsson TN, Holmgren A, Contel M, Goldberg JB, Mead JR. Auranofin and N-heterocyclic carbene gold-analogs are potent inhibitors of the bacteria Helicobacter pylori. Fems Microbiology Letters. PMID 27279627 DOI: 10.1093/Femsle/Fnw148 |
0.326 |
|
| 2016 |
Alvarez-Zaldiernas C, Lu J, Zheng Y, Yang H, Blasi J, Solsona C, Holmgren A. Cellular redox Systems impact the Aggregation of Cu-Zn Superoxide Dismutase linked to Familial Amyotrophic Lateral Sclerosis. The Journal of Biological Chemistry. PMID 27261461 DOI: 10.1074/Jbc.M115.708230 |
0.321 |
|
| 2016 |
Coppo L, Montano SJ, Padilla A, Holmgren A. Determination of glutaredoxin enzyme activity and protein S-glutathionylation using fluorescent eosin-glutathione. Analytical Biochemistry. PMID 26836485 DOI: 10.1016/J.Ab.2016.01.012 |
0.34 |
|
| 2016 |
Lei XG, Zhu JH, Cheng WH, Bao Y, Ho YS, Reddi AR, Holmgren A, Arnér ES. Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications. Physiological Reviews. 96: 307-64. PMID 26681794 DOI: 10.1152/Physrev.00010.2014 |
0.359 |
|
| 2015 |
Liang W, Fernandes AP, Holmgren A, Li X, Zhong L. Bacterial thioredoxin and thioredoxin reductase as mediators for epigallocatechin 3-gallate-induced antimicrobial action. The Febs Journal. PMID 26546231 DOI: 10.1111/Febs.13587 |
0.331 |
|
| 2015 |
Zhang X, Lu J, Ren X, Du Y, Zheng Y, Ioannou PV, Holmgren A. Oxidation of structural cysteine residues in thioredoxin 1 by aromatic arsenicals enhances cancer cell cytotoxicity caused by the inhibition of thioredoxin reductase 1. Free Radical Biology & Medicine. PMID 26169724 DOI: 10.1016/J.Freeradbiomed.2015.07.010 |
0.373 |
|
| 2015 |
Shelar SB, Kaminska KK, Reddy SA, Kumar D, Tan CT, Yu VC, Lu J, Holmgren A, Hagen T, Chew EH. Thioredoxin-dependent regulation of AIF-mediated DNA damage. Free Radical Biology & Medicine. PMID 26119781 DOI: 10.1016/J.Freeradbiomed.2015.06.029 |
0.344 |
|
| 2015 |
Rodrigues J, Branco V, Lu J, Holmgren A, Carvalho C. Toxicological effects of thiomersal and ethylmercury: Inhibition of the thioredoxin system and NADP(+)-dependent dehydrogenases of the pentose phosphate pathway. Toxicology and Applied Pharmacology. 286: 216-23. PMID 25981166 DOI: 10.1016/J.Taap.2015.05.002 |
0.319 |
|
| 2015 |
Branco V, Lu J, Holmgren A, Carvalho C. Effect of mercury compounds over the redox state of thioredoxin 1 and 2 and its relation with glutathione levels and glutaredoxin activity in human neuroblastoma cells Toxicology Letters. 238: S314. DOI: 10.1016/J.Toxlet.2015.08.898 |
0.305 |
|
| 2014 |
Branco V, Godinho-Santos A, Gonçalves J, Lu J, Holmgren A, Carvalho C. Mitochondrial thioredoxin reductase inhibition, selenium status, and Nrf-2 activation are determinant factors modulating the toxicity of mercury compounds. Free Radical Biology & Medicine. 73: 95-105. PMID 24816296 DOI: 10.1016/J.Freeradbiomed.2014.04.030 |
0.335 |
|
| 2014 |
Pader I, Sengupta R, Cebula M, Xu J, Lundberg JO, Holmgren A, Johansson K, Arnér ES. Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase. Proceedings of the National Academy of Sciences of the United States of America. 111: 6964-9. PMID 24778250 DOI: 10.1073/Pnas.1317320111 |
0.376 |
|
| 2014 |
Sengupta R, Holmgren A. Thioredoxin and glutaredoxin-mediated redox regulation of ribonucleotide reductase. World Journal of Biological Chemistry. 5: 68-74. PMID 24600515 DOI: 10.4331/Wjbc.V5.I1.68 |
0.311 |
|
| 2014 |
Lu J, Holmgren A. The thioredoxin superfamily in oxidative protein folding. Antioxidants & Redox Signaling. 21: 457-70. PMID 24483600 DOI: 10.1089/Ars.2014.5849 |
0.374 |
|
| 2014 |
Montano SJ, Lu J, Gustafsson TN, Holmgren A. Activity assays of mammalian thioredoxin and thioredoxin reductase: fluorescent disulfide substrates, mechanisms, and use with tissue samples. Analytical Biochemistry. 449: 139-46. PMID 24374250 DOI: 10.1016/J.Ab.2013.12.025 |
0.371 |
|
| 2014 |
Lu J, Holmgren A. The thioredoxin antioxidant system. Free Radical Biology & Medicine. 66: 75-87. PMID 23899494 DOI: 10.1016/J.Freeradbiomed.2013.07.036 |
0.41 |
|
| 2014 |
Du Y, Zhang H, Montano S, Hegestam J, Ekberg NR, Holmgren A, Brismar K, Ungerstedt JS. Plasma glutaredoxin activity in healthy subjects and patients with abnormal glucose levels or overt type 2 diabetes. Acta Diabetologica. 51: 225-32. PMID 23836328 DOI: 10.1007/S00592-013-0498-2 |
0.316 |
|
| 2013 |
Bräutigam L, Jensen LD, Poschmann G, Nyström S, Bannenberg S, Dreij K, Lepka K, Prozorovski T, Montano SJ, Aktas O, Uhlén P, Stühler K, Cao Y, Holmgren A, Berndt C. Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1. Proceedings of the National Academy of Sciences of the United States of America. 110: 20057-62. PMID 24277839 DOI: 10.1073/Pnas.1313753110 |
0.339 |
|
| 2013 |
Du Y, Zhang H, Zhang X, Lu J, Holmgren A. Thioredoxin 1 is inactivated due to oxidation induced by peroxiredoxin under oxidative stress and reactivated by the glutaredoxin system. The Journal of Biological Chemistry. 288: 32241-7. PMID 24062305 DOI: 10.1074/Jbc.M113.495150 |
0.407 |
|
| 2013 |
Lu J, Vodnala SK, Gustavsson AL, Gustafsson TN, Sjöberg B, Johansson HA, Kumar S, Tjernberg A, Engman L, Rottenberg ME, Holmgren A. Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei. The Journal of Biological Chemistry. 288: 27456-68. PMID 23900839 DOI: 10.1074/Jbc.M113.495101 |
0.363 |
|
| 2013 |
Aguilar-Melero P, Prieto-Álamo MJ, Jurado J, Holmgren A, Pueyo C. Proteomics in HepG2 hepatocarcinoma cells with stably silenced expression of PRDX1. Journal of Proteomics. 79: 161-71. PMID 23277276 DOI: 10.1016/J.Jprot.2012.12.005 |
0.364 |
|
| 2013 |
Lu J, Vlamis-Gardikas A, Kandasamy K, Zhao R, Gustafsson TN, Engstrand L, Hoffner S, Engman L, Holmgren A. Inhibition of bacterial thioredoxin reductase: an antibiotic mechanism targeting bacteria lacking glutathione. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1394-403. PMID 23248236 DOI: 10.1096/Fj.12-223305 |
0.374 |
|
| 2013 |
Sengupta R, Holmgren A. Thioredoxin and thioredoxin reductase in relation to reversible S-nitrosylation. Antioxidants & Redox Signaling. 18: 259-69. PMID 22702224 DOI: 10.1089/Ars.2012.4716 |
0.368 |
|
| 2012 |
Kosuri P, Alegre-Cebollada J, Feng J, Kaplan A, Inglés-Prieto A, Badilla CL, Stockwell BR, Sanchez-Ruiz JM, Holmgren A, Fernández JM. Protein folding drives disulfide formation. Cell. 151: 794-806. PMID 23141538 DOI: 10.1016/J.Cell.2012.09.036 |
0.381 |
|
| 2012 |
Gustafsson TN, Sahlin M, Lu J, Sjöberg BM, Holmgren A. Bacillus anthracis thioredoxin systems, characterization and role as electron donors for ribonucleotide reductase. The Journal of Biological Chemistry. 287: 39686-97. PMID 23012357 DOI: 10.1074/Jbc.M112.413427 |
0.371 |
|
| 2012 |
Ungerstedt J, Du Y, Zhang H, Nair D, Holmgren A. In vivo redox state of human thioredoxin and redox shift by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA). Free Radical Biology & Medicine. 53: 2002-7. PMID 23010496 DOI: 10.1016/J.Freeradbiomed.2012.09.019 |
0.425 |
|
| 2012 |
Du Y, Zhang H, Lu J, Holmgren A. Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose. The Journal of Biological Chemistry. 287: 38210-9. PMID 22977247 DOI: 10.1074/Jbc.M112.392225 |
0.413 |
|
| 2012 |
Branco V, Ramos P, Canário J, Lu J, Holmgren A, Carvalho C. Biomarkers of adverse response to mercury: histopathology versus thioredoxin reductase activity. Journal of Biomedicine & Biotechnology. 2012: 359879. PMID 22888199 DOI: 10.1155/2012/359879 |
0.307 |
|
| 2012 |
Buchanan BB, Holmgren A, Jacquot JP, Scheibe R. Fifty years in the thioredoxin field and a bountiful harvest. Biochimica Et Biophysica Acta. 1820: 1822-9. PMID 22863419 DOI: 10.1016/J.Bbagen.2012.07.006 |
0.6 |
|
| 2012 |
Paz MM, Zhang X, Lu J, Holmgren A. A new mechanism of action for the anticancer drug mitomycin C: mechanism-based inhibition of thioredoxin reductase. Chemical Research in Toxicology. 25: 1502-11. PMID 22694104 DOI: 10.1021/Tx3002065 |
0.348 |
|
| 2012 |
Lu J, Holmgren A. Thioredoxin system in cell death progression. Antioxidants & Redox Signaling. 17: 1738-47. PMID 22530689 DOI: 10.1089/Ars.2012.4650 |
0.331 |
|
| 2012 |
Branco V, Canário J, Lu J, Holmgren A, Carvalho C. Mercury and selenium interaction in vivo: effects on thioredoxin reductase and glutathione peroxidase. Free Radical Biology & Medicine. 52: 781-93. PMID 22198265 DOI: 10.1016/J.Freeradbiomed.2011.12.002 |
0.302 |
|
| 2012 |
Sengupta R, Holmgren A. The role of thioredoxin in the regulation of cellular processes by S-nitrosylation. Biochimica Et Biophysica Acta. 1820: 689-700. PMID 21878369 DOI: 10.1016/J.Bbagen.2011.08.012 |
0.332 |
|
| 2012 |
Carvalho C, Branco V, Canário J, Gonçalves J, Lu J, Holmgren A. Mercury and selenium effects on HepG2 cells: TrxR activity and expression levels Toxicology Letters. 211. DOI: 10.1016/J.Toxlet.2012.03.443 |
0.302 |
|
| 2011 |
Bräutigam L, Schütte LD, Godoy JR, Prozorovski T, Gellert M, Hauptmann G, Holmgren A, Lillig CH, Berndt C. Vertebrate-specific glutaredoxin is essential for brain development. Proceedings of the National Academy of Sciences of the United States of America. 108: 20532-7. PMID 22139372 DOI: 10.1073/Pnas.1110085108 |
0.332 |
|
| 2011 |
Berndt C, Kurz T, Bannenberg S, Jacob R, Holmgren A, Brunk UT. Ascorbate and endocytosed Motexafin gadolinium induce lysosomal rupture. Cancer Letters. 307: 119-23. PMID 21492999 DOI: 10.1016/J.Canlet.2011.03.023 |
0.301 |
|
| 2011 |
Perez-Jimenez R, Inglés-Prieto A, Zhao ZM, Sanchez-Romero I, Alegre-Cebollada J, Kosuri P, Garcia-Manyes S, Kappock TJ, Tanokura M, Holmgren A, Sanchez-Ruiz JM, Gaucher EA, Fernandez JM. Single-molecule paleoenzymology probes the chemistry of resurrected enzymes. Nature Structural & Molecular Biology. 18: 592-6. PMID 21460845 DOI: 10.1038/Nsmb.2020 |
0.33 |
|
| 2011 |
Cortes-Bratti X, Bassères E, Herrera-Rodriguez F, Botero-Kleiven S, Coppotelli G, Andersen JB, Masucci MG, Holmgren A, Chaves-Olarte E, Frisan T, Avila-Cariño J. Thioredoxin 80-activated-monocytes (TAMs) inhibit the replication of intracellular pathogens. Plos One. 6: e16960. PMID 21365006 DOI: 10.1371/Journal.Pone.0016960 |
0.325 |
|
| 2011 |
Zhang X, Zheng Y, Fried LE, Du Y, Montano SJ, Sohn A, Lefkove B, Holmgren L, Arbiser JL, Holmgren A, Lu J. Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes. Free Radical Biology & Medicine. 50: 811-20. PMID 21215310 DOI: 10.1016/J.Freeradbiomed.2010.12.036 |
0.34 |
|
| 2011 |
Carvalho CM, Lu J, Zhang X, Arnér ES, Holmgren A. Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 370-81. PMID 20810785 DOI: 10.1096/Fj.10-157594 |
0.359 |
|
| 2011 |
Kosuri P, Kaplan A, Inglés-Prieto Á, Badilla CL, Stockwell BR, Sánchez-Ruiz JM, Holmgren A, Fernández JM. Unraveling the Mechanisms of Oxidative Folding using Single Molecule Force Spectroscopy Biophysical Journal. 100: 480a. DOI: 10.1016/J.Bpj.2010.12.2812 |
0.424 |
|
| 2011 |
Kosuri P, Chen B, Holmgren A, Fernández JM. Mechanical Tuning of a Catalytic Cystein PKA in Thioredoxin Biophysical Journal. 100: 219a. DOI: 10.1016/J.Bpj.2010.12.1408 |
0.356 |
|
| 2010 |
Schoenmakers E, Agostini M, Mitchell C, Schoenmakers N, Papp L, Rajanayagam O, Padidela R, Ceron-Gutierrez L, Doffinger R, Prevosto C, Luan J, Montano S, Lu J, Castanet M, Clemons N, ... ... Holmgren A, et al. Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans. The Journal of Clinical Investigation. 120: 4220-35. PMID 21084748 DOI: 10.1172/Jci43653 |
0.341 |
|
| 2010 |
Holmgren A, Sengupta R. The use of thiols by ribonucleotide reductase. Free Radical Biology & Medicine. 49: 1617-28. PMID 20851762 DOI: 10.1016/J.Freeradbiomed.2010.09.005 |
0.346 |
|
| 2010 |
Holmgren A, Lu J. Thioredoxin and thioredoxin reductase: current research with special reference to human disease. Biochemical and Biophysical Research Communications. 396: 120-4. PMID 20494123 DOI: 10.1016/J.Bbrc.2010.03.083 |
0.392 |
|
| 2010 |
Chew EH, Nagle AA, Zhang Y, Scarmagnani S, Palaniappan P, Bradshaw TD, Holmgren A, Westwell AD. Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention. Free Radical Biology & Medicine. 48: 98-111. PMID 19837157 DOI: 10.1016/J.Freeradbiomed.2009.10.028 |
0.333 |
|
| 2010 |
Papp LV, Lu J, Bolderson E, Boucher D, Singh R, Holmgren A, Khanna KK. SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress. Antioxidants & Redox Signaling. 12: 797-808. PMID 19803747 DOI: 10.1089/Ars.2009.2913 |
0.374 |
|
| 2009 |
Perez-Jimenez R, Li J, Kosuri P, Sanchez-Romero I, Wiita AP, Rodriguez-Larrea D, Chueca A, Holmgren A, Miranda-Vizuete A, Becker K, Cho SH, Beckwith J, Gelhaye E, Jacquot JP, Gaucher EA, et al. Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nature Structural & Molecular Biology. 16: 890-6. PMID 19597482 DOI: 10.1038/Nsmb.1627 |
0.519 |
|
| 2009 |
Lu J, Berndt C, Holmgren A. Metabolism of selenium compounds catalyzed by the mammalian selenoprotein thioredoxin reductase. Biochimica Et Biophysica Acta. 1790: 1513-9. PMID 19406206 DOI: 10.1016/J.Bbagen.2009.04.013 |
0.376 |
|
| 2009 |
Lu J, Zhong L, Lönn ME, Burk RF, Hill KE, Holmgren A. Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2394-402. PMID 19351701 DOI: 10.1096/Fj.08-127662 |
0.344 |
|
| 2009 |
Fridlich R, Delalande F, Jaillard C, Lu J, Poidevin L, Cronin T, Perrocheau L, Millet-Puel G, Niepon ML, Poch O, Holmgren A, Van Dorsselaer A, Sahel JA, Léveillard T. The thioredoxin-like protein rod-derived cone viability factor (RdCVFL) interacts with TAU and inhibits its phosphorylation in the retina. Molecular & Cellular Proteomics : McP. 8: 1206-18. PMID 19279044 DOI: 10.1074/Mcp.M800406-Mcp200 |
0.326 |
|
| 2009 |
Zahedi Avval F, Holmgren A. Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for Mammalian s phase ribonucleotide reductase. The Journal of Biological Chemistry. 284: 8233-40. PMID 19176520 DOI: 10.1074/Jbc.M809338200 |
0.382 |
|
| 2009 |
Paupe V, Dassa EP, Goncalves S, Auchère F, Lönn M, Holmgren A, Rustin P. Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia. Plos One. 4: e4253. PMID 19158945 DOI: 10.1371/Journal.Pone.0004253 |
0.319 |
|
| 2009 |
Zahedi Avval F, Berndt C, Pramanik A, Holmgren A. Mechanism of inhibition of ribonucleotide reductase with motexafin gadolinium (MGd). Biochemical and Biophysical Research Communications. 379: 775-9. PMID 19121624 DOI: 10.1016/J.Bbrc.2008.12.128 |
0.336 |
|
| 2009 |
Du Y, Wu Y, Cao X, Cui W, Zhang H, Tian W, Ji M, Holmgren A, Zhong L. Inhibition of mammalian thioredoxin reductase by black tea and its constituents: implications for anticancer actions. Biochimie. 91: 434-44. PMID 19059456 DOI: 10.1016/J.Biochi.2008.11.005 |
0.338 |
|
| 2009 |
Hudemann C, Lönn ME, Godoy JR, Zahedi Avval F, Capani F, Holmgren A, Lillig CH. Identification, expression pattern, and characterization of mouse glutaredoxin 2 isoforms. Antioxidants & Redox Signaling. 11: 1-14. PMID 18707224 DOI: 10.1089/Ars.2008.2068 |
0.326 |
|
| 2009 |
Gurmu D, Lu J, Johnson KA, Nordlund P, Holmgren A, Erlandsen H. The crystal structure of the protein YhaK from Escherichia coli reveals a new subclass of redox sensitive enterobacterial bicupins. Proteins. 74: 18-31. PMID 18561187 DOI: 10.1002/Prot.22128 |
0.407 |
|
| 2008 |
Wang Y, Zhang H, Holmgren A, Tian W, Zhong L. Inhibitory effect of green tea extract and (-)-epigallocatechin-3-gallate on mammalian thioredoxin reductase and HeLa cell viability. Oncology Reports. 20: 1479-87. PMID 19020731 DOI: 10.3892/Or_00000169 |
0.36 |
|
| 2008 |
Hashemy SI, Holmgren A. Regulation of the catalytic activity and structure of human thioredoxin 1 via oxidation and S-nitrosylation of cysteine residues. The Journal of Biological Chemistry. 283: 21890-8. PMID 18544525 DOI: 10.1074/Jbc.M801047200 |
0.429 |
|
| 2008 |
Berndt C, Lillig CH, Holmgren A. Thioredoxins and glutaredoxins as facilitators of protein folding. Biochimica Et Biophysica Acta. 1783: 641-50. PMID 18331844 DOI: 10.1016/J.Bbamcr.2008.02.003 |
0.395 |
|
| 2008 |
Carvalho CM, Chew EH, Hashemy SI, Lu J, Holmgren A. Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity. The Journal of Biological Chemistry. 283: 11913-23. PMID 18321861 DOI: 10.1074/Jbc.M710133200 |
0.376 |
|
| 2008 |
Chew EH, Lu J, Bradshaw TD, Holmgren A. Thioredoxin reductase inhibition by antitumor quinols: a quinol pharmacophore effect correlating to antiproliferative activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2072-83. PMID 18180330 DOI: 10.1096/Fj.07-101477 |
0.358 |
|
| 2008 |
Lönn ME, Hudemann C, Berndt C, Cherkasov V, Capani F, Holmgren A, Lillig CH. Expression pattern of human glutaredoxin 2 isoforms: identification and characterization of two testis/cancer cell-specific isoforms. Antioxidants & Redox Signaling. 10: 547-558. PMID 18092940 DOI: 10.1089/Ars.2007.1821 |
0.311 |
|
| 2007 |
Wiita AP, Perez-Jimenez R, Walther KA, Gräter F, Berne BJ, Holmgren A, Sanchez-Ruiz JM, Fernandez JM. Probing the chemistry of thioredoxin catalysis with force. Nature. 450: 124-7. PMID 17972886 DOI: 10.1038/Nature06231 |
0.355 |
|
| 2007 |
Lu J, Chew E, Holmgren A. Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide Proceedings of the National Academy of Sciences of the United States of America. 104: 12288-12293. PMID 17640917 DOI: 10.1073/Pnas.0701549104 |
0.39 |
|
| 2007 |
Gustafsson TN, Sandalova T, Lu J, Holmgren A, Schneider G. High-resolution structures of oxidized and reduced thioredoxin reductase from Helicobacter pylori. Acta Crystallographica Section D-Biological Crystallography. 63: 833-843. PMID 17582174 DOI: 10.1107/S0907444907026303 |
0.341 |
|
| 2007 |
Sagemark J, Elgán TH, Bürglin TR, Johansson C, Holmgren A, Berndt KD. Redox properties and evolution of human glutaredoxins. Proteins. 68: 879-92. PMID 17546662 DOI: 10.1002/Prot.21416 |
0.332 |
|
| 2007 |
Lassing I, Schmitzberger F, Björnstedt M, Holmgren A, Nordlund P, Schutt CE, Lindberg U. Molecular and structural basis for redox regulation of beta-actin. Journal of Molecular Biology. 370: 331-48. PMID 17521670 DOI: 10.1016/J.Jmb.2007.04.056 |
0.315 |
|
| 2007 |
Papp LV, Lu J, Holmgren A, Khanna KK. From selenium to selenoproteins: Synthesis, identity, and their role in human health Antioxidants & Redox Signaling. 9: 775-806. PMID 17508906 DOI: 10.1089/Ars.2007.1528 |
0.329 |
|
| 2007 |
Hashemy SI, Johansson C, Berndt C, Lillig CH, Holmgren A. Oxidation and S-nitrosylation of cysteines in human cytosolic and mitochondrial glutaredoxins: effects on structure and activity. The Journal of Biological Chemistry. 282: 14428-36. PMID 17355958 DOI: 10.1074/Jbc.M700927200 |
0.423 |
|
| 2007 |
Berndt C, Lillig CH, Holmgren A. Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system American Journal of Physiology-Heart and Circulatory Physiology. 292. PMID 17172268 DOI: 10.1152/Ajpheart.01162.2006 |
0.313 |
|
| 2007 |
Berndt C, Hudemann C, Hanschmann E, Axelsson R, Holmgren A, Lillig CH. How does iron-sulfur cluster coordination regulate the activity of human glutaredoxin 2? Antioxidants & Redox Signaling. 9: 151-157. PMID 17115894 DOI: 10.1089/Ars.2007.9.151 |
0.335 |
|
| 2007 |
Lillig CH, Holmgren A. Thioredoxin and related molecules--from biology to health and disease. Antioxidants & Redox Signaling. 9: 25-47. PMID 17115886 DOI: 10.1089/Ars.2007.9.25 |
0.366 |
|
| 2006 |
Arnér ESJ, Holmgren A. The thioredoxin system in cancer. Seminars in Cancer Biology. 16: 420-426. PMID 17092741 DOI: 10.1016/J.Semcancer.2006.10.009 |
0.405 |
|
| 2006 |
Papp LV, Lu J, Striebel F, Kennedy D, Holmgren A, Khanna KK. The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Molecular and Cellular Biology. 26: 4895-910. PMID 16782878 DOI: 10.1128/Mcb.02284-05 |
0.39 |
|
| 2006 |
Lu J, Papp LV, Fang J, Rodriguez-Nieto S, Zhivotovsky B, Holmgren A. Inhibition of mammalian thioredoxin reductase by some flavonoids: Implications for myricetin and quercetin anticancer activity Cancer Research. 66: 4410-4418. PMID 16618767 DOI: 10.1158/0008-5472.Can-05-3310 |
0.371 |
|
| 2006 |
Hashemy SI, Ungerstedt JS, Avval FZ, Holmgren A. Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase. Journal of Biological Chemistry. 281: 10691-10697. PMID 16481328 DOI: 10.1074/Jbc.M511373200 |
0.38 |
|
| 2006 |
Fang J, Holmgren A. Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo. Journal of the American Chemical Society. 128: 1879-85. PMID 16464088 DOI: 10.1021/JA057358L |
0.321 |
|
| 2006 |
Lundberg M, Holmgren A, Johansson M. Human glutaredoxin 2 affinity tag for recombinant peptide and protein purification Protein Expression and Purification. 45: 37-42. PMID 16112873 DOI: 10.1016/J.Pep.2005.07.001 |
0.321 |
|
| 2005 |
Arnér ESJ, Holmgren A. Measurement of Thioredoxin and Thioredoxin Reductase Current Protocols in Immunology. 24. PMID 20954152 DOI: 10.1002/0471140856.Tx0704S05 |
0.376 |
|
| 2005 |
Holmgren A, Johansson C, Berndt C, Lönn ME, Hudemann C, Lillig CH. Thiol redox control via thioredoxin and glutaredoxin systems. Biochemical Society Transactions. 33: 1375-7. PMID 16246122 DOI: 10.1042/Bst20051375 |
0.303 |
|
| 2005 |
Bizzarri C, Holmgren A, Pekkari K, Chang G, Colotta F, Ghezzi P, Bertini R. Requirements for the different cysteines in the chemotactic and desensitizing activity of human thioredoxin. Antioxidants & Redox Signaling. 7: 1189-1194. PMID 16115022 DOI: 10.1089/Ars.2005.7.1189 |
0.346 |
|
| 2005 |
Fang J, Zhong L, Zhao R, Holmgren A. Ebselen: A thioredoxin reductase-dependent catalyst for α-tocopherol quinone reduction Toxicology and Applied Pharmacology. 207: 103-109. PMID 15979675 DOI: 10.1016/J.Taap.2005.02.022 |
0.365 |
|
| 2005 |
Lillig CH, Berndt C, Vergnolle O, Lönn ME, Hudemann C, Bill E, Holmgren A. Characterization of human glutaredoxin 2 as iron–sulfur protein: A possible role as redox sensor Proceedings of the National Academy of Sciences of the United States of America. 102: 8168-8173. PMID 15917333 DOI: 10.1073/Pnas.0500735102 |
0.38 |
|
| 2005 |
Fang J, Lu J, Holmgren A. Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity. Journal of Biological Chemistry. 280: 25284-25290. PMID 15879598 DOI: 10.1074/Jbc.M414645200 |
0.415 |
|
| 2005 |
Fernandes AP, Fladvad M, Berndt C, Andrésen C, Lillig CH, Neubauer P, Sunnerhagen M, Holmgren A, Vlamis-Gardikas A. A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase Journal of Biological Chemistry. 280: 24544-24552. PMID 15833738 DOI: 10.1074/Jbc.M500678200 |
0.444 |
|
| 2005 |
Xiao R, Lundström-Ljung J, Holmgren A, Gilbert HF. Catalysis of Thiol/Disulfide Exchange GLUTAREDOXIN 1 AND PROTEIN-DISULFIDE ISOMERASE USE DIFFERENT MECHANISMS TO ENHANCE OXIDASE AND REDUCTASE ACTIVITIES Journal of Biological Chemistry. 280: 21099-21106. PMID 15814611 DOI: 10.1074/Jbc.M411476200 |
0.427 |
|
| 2005 |
Enoksson M, Fernandes AP, Prast S, Lillig CH, Holmgren A, Orrenius S. Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release. Biochemical and Biophysical Research Communications. 327: 774-779. PMID 15649413 DOI: 10.1016/J.Bbrc.2004.12.067 |
0.321 |
|
| 2005 |
Randahl H, Slabý I, Holmgren A. An Improved Purification Method and a Physical Characterization of Phage T7 DNA Polymerase Febs Journal. 128: 445-449. PMID 6759119 DOI: 10.1111/J.1432-1033.1982.Tb06984.X |
0.302 |
|
| 2004 |
Lindberg MJ, Normark J, Holmgren A, Oliveberg M. Folding of human superoxide dismutase: Disulfide reduction prevents dimerization and produces marginally stable monomers Proceedings of the National Academy of Sciences of the United States of America. 101: 15893-15898. PMID 15522970 DOI: 10.1073/Pnas.0403979101 |
0.339 |
|
| 2004 |
Xiao R, Wilkinson B, Solovyov A, Winther JR, Holmgren A, Lundström-Ljung J, Gilbert HF. The contributions of protein disulfide isomerase and its homologues to oxidative protein folding in the yeast endoplasmic reticulum. The Journal of Biological Chemistry. 279: 49780-6. PMID 15377672 DOI: 10.1074/Jbc.M409210200 |
0.393 |
|
| 2004 |
Lillig CH, Lönn ME, Enoksson M, Fernandes AP, Holmgren A. Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide. Proceedings of the National Academy of Sciences of the United States of America. 101: 13227-13232. PMID 15328416 DOI: 10.1073/Pnas.0401896101 |
0.358 |
|
| 2004 |
Lundberg M, Fernandes AP, Kumar S, Holmgren A. Cellular and plasma levels of human glutaredoxin 1 and 2 detected by sensitive ELISA systems. Biochemical and Biophysical Research Communications. 319: 801-9. PMID 15184054 DOI: 10.1016/J.Bbrc.2004.04.199 |
0.318 |
|
| 2004 |
Zhao R, Holmgren A. Ebselen is a dehydroascorbate reductase mimic, facilitating the recycling of ascorbate via mammalian thioredoxin systems. Antioxidants & Redox Signaling. 6: 99-104. PMID 14713340 DOI: 10.1089/152308604771978390 |
0.302 |
|
| 2004 |
Fernandes AP, Holmgren A. Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system. Antioxidants & Redox Signaling. 6: 63-74. PMID 14713336 DOI: 10.1089/152308604771978354 |
0.45 |
|
| 2004 |
Pekkari K, Holmgren A. Truncated Thioredoxin: Physiological Functions and Mechanism Antioxidants & Redox Signaling. 6: 53-61. PMID 14713335 DOI: 10.1089/152308604771978345 |
0.351 |
|
| 2004 |
Johansson C, Lillig CH, Holmgren A. Human Mitochondrial Glutaredoxin Reduces S-Glutathionylated Proteins with High Affinity Accepting Electrons from Either Glutathione or Thioredoxin Reductase Journal of Biological Chemistry. 279: 7537-7543. PMID 14676218 DOI: 10.1074/Jbc.M312719200 |
0.412 |
|
| 2003 |
Lysell J, Vladic YS, Ciarlo N, Holmgren A, Sahlin L. Immunohistochemical determination of thioredoxin and glutaredoxin distribution in the human cervix, and possible relation to cervical ripening. Gynecological Endocrinology. 17: 303-310. PMID 14503974 DOI: 10.1080/Gye.17.4.303.310 |
0.333 |
|
| 2003 |
Lillig CH, Potamitou A, Schwenn J, Vlamis-Gardikas A, Holmgren A. Redox Regulation of 3′-Phosphoadenylylsulfate Reductase from Escherichia coli by Glutathione and Glutaredoxins Journal of Biological Chemistry. 278: 22325-22330. PMID 12682041 DOI: 10.1074/Jbc.M302304200 |
0.419 |
|
| 2003 |
Singha NC, Vlamis-Gardikas A, Holmgren A. Real-time kinetics of the interaction between the two subunits, Escherichia coli thioredoxin and gene 5 protein of phage T7 DNA polymerase. Journal of Biological Chemistry. 278: 21421-21428. PMID 12670954 DOI: 10.1074/Jbc.M302310200 |
0.304 |
|
| 2003 |
Pekkari K, Avila-Cariño J, Gurunath R, Bengtsson A, Scheynius A, Holmgren A. Truncated thioredoxin (Trx80) exerts unique mitogenic cytokine effects via a mechanism independent of thiol oxido-reductase activity. Febs Letters. 539: 143-8. PMID 12650942 DOI: 10.1016/S0014-5793(03)00214-X |
0.316 |
|
| 2003 |
Rouhier N, Vlamis-Gardikas A, Lillig CH, Berndt C, Schwenn J, Holmgren A, Jacquot J. Characterization of the redox properties of poplar glutaredoxin. Antioxidants & Redox Signaling. 5: 15-22. PMID 12626113 DOI: 10.1089/152308603321223504 |
0.649 |
|
| 2003 |
Kern R, Malki A, Holmgren A, Richarme G. Chaperone properties of Escherichia coli thioredoxin and thioredoxin reductase. Biochemical Journal. 371: 965-972. PMID 12549977 DOI: 10.1042/Bj20030093 |
0.378 |
|
| 2003 |
Söderdahl T, Enoksson M, Lundberg M, Holmgren A, Ottersen OP, Orrenius S, Bolcsfoldi G, Cotgreave IA. Visualization of the compartmentalization of glutathione and protein-glutathione mixed disulfides in cultured cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 124-6. PMID 12475911 DOI: 10.1096/Fj.02-0259Fje |
0.314 |
|
| 2002 |
Jiménez A, Johansson C, Ljung J, Sagemark J, Berndt KD, Ren B, Tibbelin G, Ladenstein R, Kieselbach T, Holmgren A, Gustafsson JA, Miranda-Vizuete A. Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity Febs Letters. 530: 79-84. PMID 12387870 DOI: 10.1016/S0014-5793(02)03417-8 |
0.336 |
|
| 2002 |
Lind C, Gerdes R, Hamnell Y, Schuppe-Koistinen I, Löwenhielm HBv, Holmgren A, Cotgreave IA. Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis. Archives of Biochemistry and Biophysics. 406: 229-240. PMID 12361711 DOI: 10.1016/S0003-9861(02)00468-X |
0.373 |
|
| 2002 |
Zhao R, Holmgren A. A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase Journal of Biological Chemistry. 277: 39456-39462. PMID 12177067 DOI: 10.1074/Jbc.M206452200 |
0.311 |
|
| 2002 |
Porras P, Pedrajas JR, Martı́nez-Galisteo E, Padilla CA, Johansson C, Holmgren A, Bárcena JA. Glutaredoxins catalyze the reduction of glutathione by dihydrolipoamide with high efficiency. Biochemical and Biophysical Research Communications. 295: 1046-1051. PMID 12135599 DOI: 10.1016/S0006-291X(02)00771-4 |
0.383 |
|
| 2002 |
Casagrande S, Bonetto V, Fratelli M, Gianazza E, Eberini I, Massignan T, Salmona M, Chang G, Holmgren A, Ghezzi P. Glutathionylation of human thioredoxin: A possible crosstalk between the glutathione and thioredoxin systems Proceedings of the National Academy of Sciences of the United States of America. 99: 9745-9749. PMID 12119401 DOI: 10.1073/Pnas.152168599 |
0.412 |
|
| 2002 |
Zhao R, Masayasu H, Holmgren A. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proceedings of the National Academy of Sciences of the United States of America. 99: 8579-8584. PMID 12070343 DOI: 10.1073/Pnas.122061399 |
0.404 |
|
| 2002 |
Zhong L, Holmgren A. Mammalian thioredoxin reductases as hydroperoxide reductases Methods in Enzymology. 347: 236-243. PMID 11898412 DOI: 10.1016/S0076-6879(02)47023-1 |
0.373 |
|
| 2002 |
Potamitou A, Holmgren A, Vlamis-Gardikas A. Protein levels of Escherichia coli thioredoxins and glutaredoxins and their relation to null mutants, growth phase, and function. Journal of Biological Chemistry. 277: 18561-18567. PMID 11893749 DOI: 10.1074/Jbc.M201225200 |
0.301 |
|
| 2002 |
Vlamis-Gardikas A, Potamitou A, Zarivach R, Hochman A, Holmgren A. Characterization of Escherichia coli null mutants for glutaredoxin 2. The Journal of Biological Chemistry. 277: 10861-8. PMID 11741965 DOI: 10.1074/Jbc.M111024200 |
0.386 |
|
| 2001 |
Arnér ESJ, Nakamura H, Sasada T, Yodoi J, Holmgren A, Spyrou G. Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex. Free Radical Biology and Medicine. 31: 1170-1178. PMID 11705695 DOI: 10.1016/S0891-5849(01)00698-0 |
0.36 |
|
| 2001 |
Sandalova T, Zhong L, Lindqvist Y, Holmgren A, Schneider G. Three-dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine-dependent enzyme Proceedings of the National Academy of Sciences of the United States of America. 98: 9533-9538. PMID 11481439 DOI: 10.1073/Pnas.171178698 |
0.412 |
|
| 2001 |
Stehr M, Schneider G, Åslund F, Holmgren A, Lindqvist Y. Structural Basis for the Thioredoxin-like Activity Profile of the Glutaredoxin-like NrdH-redoxin from Escherichia coli Journal of Biological Chemistry. 276: 35836-35841. PMID 11441020 DOI: 10.1074/Jbc.M105094200 |
0.377 |
|
| 2001 |
Xiao R, Solovyov A, Gilbert HF, Holmgren A, Lundström-Ljung J. Combinations of protein-disulfide isomerase domains show that there is little correlation between isomerase activity and wild-type growth. The Journal of Biological Chemistry. 276: 27975-80. PMID 11375405 DOI: 10.1074/Jbc.M104203200 |
0.349 |
|
| 2001 |
Hammarberg T, Kuprin S, Rådmark O, Holmgren A. EPR investigation of the active site of recombinant human 5-lipoxygenase: inhibition by selenide. Biochemistry. 40: 6371-6378. PMID 11371199 DOI: 10.1021/Bi001595D |
0.308 |
|
| 2001 |
Lundberg M, Johansson C, Chandra J, Enoksson M, Jacobsson G, Ljung J, Johansson M, Holmgren A. Cloning and Expression of a Novel Human Glutaredoxin (Grx2) with Mitochondrial and Nuclear Isoforms Journal of Biological Chemistry. 276: 26269-26275. PMID 11297543 DOI: 10.1074/Jbc.M011605200 |
0.36 |
|
| 2001 |
Monje-Casas F, Jurado J, Prieto-Alamo MJ, Holmgren A, Pueyo C. Expression analysis of the nrdHIEF operon from Escherichia coli. Conditions that trigger the transcript level in vivo. The Journal of Biological Chemistry. 276: 18031-7. PMID 11278973 DOI: 10.1074/Jbc.M011728200 |
0.379 |
|
| 2000 |
Holmgren A. Antioxidant function of thioredoxin and glutaredoxin systems. Antioxidants & Redox Signaling. 2: 811-820. PMID 11213485 DOI: 10.1089/Ars.2000.2.4-811 |
0.404 |
|
| 2000 |
Nordstrand K, Sandström A, Åslund F, Holmgren A, Otting G, Berndt KD. NMR structure of oxidized glutaredoxin 3 from Escherichia coli Journal of Molecular Biology. 303: 423-432. PMID 11031118 DOI: 10.1006/Jmbi.2000.4145 |
0.384 |
|
| 2000 |
Arnér ESJ, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Febs Journal. 267: 6102-6109. PMID 11012661 DOI: 10.1046/J.1432-1327.2000.01701.X |
0.435 |
|
| 2000 |
Pekkari K, Gurunath R, Arnér ESJ, Holmgren A. Truncated Thioredoxin Is a Mitogenic Cytokine for Resting Human Peripheral Blood Mononuclear Cells and Is Present in Human Plasma Journal of Biological Chemistry. 275: 37474-37480. PMID 10982790 DOI: 10.1074/Jbc.M001012200 |
0.327 |
|
| 2000 |
Zhong L, Persson K, Sandalova T, Schneider G, Holmgren A. Purification, crystallization and preliminary crystallographic data for rat cytosolic selenocysteine 498 to cysteine mutant thioredoxin reductase. Acta Crystallographica Section D-Biological Crystallography. 56: 1191-1193. PMID 10957643 DOI: 10.1107/S0907444900009458 |
0.356 |
|
| 2000 |
Eftekharpour E, Holmgren A, Juurlink BHJ. Thioredoxin reductase and glutathione synthesis is upregulated by t-butylhydroquinone in cortical astrocytes but not in cortical neurons Glia. 31: 241-248. PMID 10941150 DOI: 10.1002/1098-1136(200009)31:3<241::Aid-Glia50>3.0.Co;2-9 |
0.356 |
|
| 2000 |
Zhong L, Holmgren A. Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations. Journal of Biological Chemistry. 275: 18121-18128. PMID 10849437 DOI: 10.1074/Jbc.M000690200 |
0.386 |
|
| 2000 |
Zhong L, Arnér ESJ, Holmgren A. Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence Proceedings of the National Academy of Sciences of the United States of America. 97: 5854-5859. PMID 10801974 DOI: 10.1073/Pnas.100114897 |
0.412 |
|
| 2000 |
Prieto-Alamo MJ, Jurado J, Gallardo-Madueno R, Monje-Casas F, Holmgren A, Pueyo C. Transcriptional regulation of glutaredoxin and thioredoxin pathways and related enzymes in response to oxidative stress. The Journal of Biological Chemistry. 275: 13398-405. PMID 10788450 DOI: 10.1074/Jbc.275.18.13398 |
0.351 |
|
| 2000 |
Holmgren A. Redox regulation by thioredoxin and thioredoxin reductase Biofactors. 11: 63-64. PMID 10705962 DOI: 10.1002/Biof.5520110117 |
0.314 |
|
| 1999 |
Arnér ESJ, Sarioglu H, Lottspeich F, Holmgren A, Böck A. High-level expression in Escherichia coli of selenocysteine-containing rat thioredoxin reductase utilizing gene fusions with engineered bacterial-type SECIS elements and co-expression with the selA, selB and selC genes. Journal of Molecular Biology. 292: 1003-1016. PMID 10512699 DOI: 10.1006/Jmbi.1999.3085 |
0.365 |
|
| 1999 |
Sasada T, Nakamura H, Ueda S, Sato N, Kitaoka Y, Gon Y, Takabayashi A, Spyrou G, Holmgren A, Yodoi J. Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II). Free Radical Biology and Medicine. 27: 504-514. PMID 10490269 DOI: 10.1016/S0891-5849(99)00101-X |
0.349 |
|
| 1999 |
Kumar S, Holmgren A. Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters. Carcinogenesis. 20: 1761-1767. PMID 10469622 DOI: 10.1093/Carcin/20.9.1761 |
0.32 |
|
| 1999 |
Bertini R, Howard OM, Dong HF, Oppenheim JJ, Bizzarri C, Sergi R, Caselli G, Pagliei S, Romines B, Wilshire JA, Mengozzi M, Nakamura H, Yodoi J, Pekkari K, Gurunath R, ... Holmgren A, et al. Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells. The Journal of Experimental Medicine. 189: 1783-9. PMID 10359582 DOI: 10.1084/Jem.189.11.1783 |
0.379 |
|
| 1999 |
Nordstrand K, Åslund F, Meunier S, Holmgren A, Otting G, Berndt KD. Direct NMR observation of the Cys-14 thiol proton of reduced Escherichia coli glutaredoxin-3 supports the presence of an active site thiol-thiolate hydrogen bond. Febs Letters. 449: 196-200. PMID 10338131 DOI: 10.1016/S0014-5793(99)00401-9 |
0.336 |
|
| 1999 |
Lillig CH, Prior A, Schwenn JD, Aslund F, Ritz D, Vlamis-Gardikas A, Holmgren A. New thioredoxins and glutaredoxins as electron donors of 3'-phosphoadenylylsulfate reductase. The Journal of Biological Chemistry. 274: 7695-8. PMID 10075658 DOI: 10.1074/Jbc.274.12.7695 |
0.322 |
|
| 1999 |
Lundström-Ljung J, Vlamis-Gardikas A, Åslund F, Holmgren A. Reactivity of glutaredoxins 1, 2 and 3 from Escherichia coli and protein disulfide isomerase towards glutathionyl-mixed disulfides in ribonuclease A. Febs Letters. 443: 85-88. PMID 9989580 DOI: 10.1016/S0014-5793(98)01698-6 |
0.391 |
|
| 1999 |
Nordstrand K, Åslund F, Holmgren A, Otting G, Berndt KD. NMR structure of Escherichia coli glutaredoxin 3-glutathione mixed disulfide complex : Implications for the enzymatic mechanism Journal of Molecular Biology. 286: 541-552. PMID 9973569 DOI: 10.1006/Jmbi.1998.2444 |
0.384 |
|
| 1999 |
Arnér ESJ, Zhong L, Holmgren A. Preparation and assay of mammalian thioredoxin and thioredoxin reductase. Methods in Enzymology. 300: 226-239. PMID 9919525 DOI: 10.1016/S0076-6879(99)00129-9 |
0.409 |
|
| 1998 |
Jeng M, Reymond MT, Tennant LL, Holmgren A, Dyson HJ. Nmr Characterization Of A Single-Cysteine Mutant Of Escherichia Coli Thioredoxin And A Covalent Thioredoxin-Peptide Complex Febs Journal. 257: 299-308. PMID 9826174 DOI: 10.1046/J.1432-1327.1998.2570299.X |
0.341 |
|
| 1998 |
Söderberg A, Sahaf B, Holmgren A, Rosén A. Monoclonal antibodies to human thioredoxin reductase. Biochemical and Biophysical Research Communications. 249: 86-9. PMID 9705836 DOI: 10.1006/Bbrc.1998.9053 |
0.312 |
|
| 1998 |
Gallardo-Madueño R, Leal JFM, Dorado G, Holmgren A, López-Barea J, Pueyo C. In Vivo Transcription of nrdAB Operon and of grxA and fpg Genes Is Triggered inEscherichia coli Lacking both Thioredoxin and Glutaredoxin 1 or Thioredoxin and Glutathione, Respectively Journal of Biological Chemistry. 273: 18382-18388. PMID 9660805 DOI: 10.1074/Jbc.273.29.18382 |
0.327 |
|
| 1998 |
Nordberg J, Zhong L, Holmgren A, Arnér ESJ. Mammalian Thioredoxin Reductase Is Irreversibly Inhibited by Dinitrohalobenzenes by Alkylation of Both the Redox Active Selenocysteine and Its Neighboring Cysteine Residue Journal of Biological Chemistry. 273: 10835-10842. PMID 9556556 DOI: 10.1074/Jbc.273.18.10835 |
0.405 |
|
| 1998 |
Zhong L, Arnér ESJ, Ljung J, Åslund F, Holmgren A. Rat and Calf Thioredoxin Reductase Are Homologous to Glutathione Reductase with a Carboxyl-terminal Elongation Containing a Conserved Catalytically Active Penultimate Selenocysteine Residue Journal of Biological Chemistry. 273: 8581-8591. PMID 9535831 DOI: 10.1074/Jbc.273.15.8581 |
0.367 |
|
| 1998 |
Nikitovic D, Holmgren A, Spyrou G. Inhibition of AP-1 DNA binding by nitric oxide involving conserved cysteine residues in Jun and Fos. Biochemical and Biophysical Research Communications. 242: 109-112. PMID 9439619 DOI: 10.1006/Bbrc.1997.7930 |
0.342 |
|
| 1997 |
Magnusson CGM, Björnstedt M, Holmgren A. Human Igg Is Substrate For The Thioredoxin System : Differential Cleavage Pattern Of Interchain Disulfide Bridges In Igg Subclasses Molecular Immunology. 34: 709-717. PMID 9430198 DOI: 10.1016/S0161-5890(97)00092-8 |
0.375 |
|
| 1997 |
Åslund F, Berndt KD, Holmgren A. Redox Potentials of Glutaredoxins and Other Thiol-Disulfide Oxidoreductases of the Thioredoxin Superfamily Determined by Direct Protein-Protein Redox Equilibria Journal of Biological Chemistry. 272: 30780-30786. PMID 9388218 DOI: 10.1074/Jbc.272.49.30780 |
0.395 |
|
| 1997 |
Sahaf B, Söderberg A, Spyrou G, Barral AM, Pekkari K, Holmgren A, Rosén A. Thioredoxin expression and localization in human cell lines: detection of full-length and truncated species. Experimental Cell Research. 236: 181-92. PMID 9344598 DOI: 10.1006/Excr.1997.3699 |
0.334 |
|
| 1997 |
Prinz WA, Aslund F, Holmgren A, Beckwith J. The role of the thioredoxin and glutaredoxin pathways in reducing protein disulfide bonds in the Escherichia coli cytoplasm. The Journal of Biological Chemistry. 272: 15661-7. PMID 9188456 DOI: 10.1074/Jbc.272.25.15661 |
0.366 |
|
| 1997 |
Vlamis-Gardikas A, Åslund F, Spyrou G, Bergman T, Holmgren A. Cloning, Overexpression, and Characterization of Glutaredoxin 2, An Atypical Glutaredoxin from Escherichia coli Journal of Biological Chemistry. 272: 11236-11243. PMID 9111025 DOI: 10.1074/Jbc.272.17.11236 |
0.377 |
|
| 1997 |
Sun C, Holmgren A, Bushweller JH. Complete 1H, 13C, and 15N NMR resonance assignments and secondary structure of human glutaredoxin in the fully reduced form. Protein Science : a Publication of the Protein Society. 6: 383-90. PMID 9041640 DOI: 10.1002/Pro.5560060214 |
0.347 |
|
| 1996 |
Arnér ESJ, Nordberg J, Holmgren A. Efficient Reduction of Lipoamide and Lipoic Acid by Mammalian Thioredoxin Reductase Biochemical and Biophysical Research Communications. 225: 268-274. PMID 8769129 DOI: 10.1006/Bbrc.1996.1165 |
0.317 |
|
| 1996 |
Nikitovic D, Holmgren A. S-Nitrosoglutathione Is Cleaved by the Thioredoxin System with Liberation of Glutathione and Redox Regulating Nitric Oxide Journal of Biological Chemistry. 271: 19180-19185. PMID 8702596 DOI: 10.1074/Jbc.271.32.19180 |
0.421 |
|
| 1996 |
Miranda-Vizuete A, Rodríguez-Ariza A, Toribio F, Holmgren A, López-Barea J, Pueyo C. The Levels of Ribonucleotide Reductase, Thioredoxin, Glutaredoxin 1, and GSH Are Balanced in Escherichia coli K12 Journal of Biological Chemistry. 271: 19099-19103. PMID 8702583 DOI: 10.1074/Jbc.271.32.19099 |
0.381 |
|
| 1996 |
Björnstedt M, Odlander B, Kuprin S, Claesson H, Holmgren A. Selenite incubated with NADPH and mammalian thioredoxin reductase yields selenide, which inhibits lipoxygenase and changes the electron spin resonance spectrum of the active site iron. Biochemistry. 35: 8511-8516. PMID 8679612 DOI: 10.1021/Bi9528762 |
0.348 |
|
| 1996 |
Andersson M, Holmgren A, Spyrou G. NK-lysin, a disulfide-containing effector peptide of T-lymphocytes, is reduced and inactivated by human thioredoxin reductase. Implication for a protective mechanism against NK-lysin cytotoxicity. Journal of Biological Chemistry. 271: 10116-10120. PMID 8626570 DOI: 10.1074/Jbc.271.17.10116 |
0.316 |
|
| 1996 |
Slaby I, Cerna V, Jeng MF, Dyson HJ, Holmgren A. Replacement of Trp28 in Escherichia coli thioredoxin by site-directed mutagenesis affects thermodynamic stability but not function Journal of Biological Chemistry. 271: 3091-3096. PMID 8621706 DOI: 10.1074/Jbc.271.6.3091 |
0.391 |
|
| 1996 |
Spyrou G, Holmgren A. Deoxyribonucleoside triphosphate pools and growth of glutathione-depleted 3T6 mouse fibroblasts Biochemical and Biophysical Research Communications. 220: 42-46. PMID 8602854 DOI: 10.1006/Bbrc.1996.0353 |
0.326 |
|
| 1995 |
Arnér ESJ, Björnstedt M, Holmgren A. 1-Chloro-2,4-dinitrobenzene Is an Irreversible Inhibitor of Human Thioredoxin Reductase LOSS OF THIOREDOXIN DISULFIDE REDUCTASE ACTIVITY IS ACCOMPANIED BY A LARGE INCREASE IN NADPH OXIDASE ACTIVITY Journal of Biological Chemistry. 270: 3479-3482. PMID 7876079 DOI: 10.1074/Jbc.270.8.3479 |
0.432 |
|
| 1995 |
Padilla CA, Martínez-Galisteo E, Bárcena JA, Spyrou G, Holmgren A. Purification from Placenta, Amino Acid Sequence, Structure Comparisons and cDNA Cloning of Human Glutaredoxin Febs Journal. 227: 27-34. PMID 7851394 DOI: 10.1111/J.1432-1033.1995.Tb20356.X |
0.368 |
|
| 1995 |
Lundström-Ljung J, Birnbach U, Rupp K, Söling HD, Holmgren A. Two resident ER-proteins, CaBP1 and CaBP2, with thioredoxin domains, are substrates for thioredoxin reductase: comparison with protein disulfide isomerase. Febs Letters. 357: 305-8. PMID 7835433 DOI: 10.1016/0014-5793(94)01386-F |
0.414 |
|
| 1995 |
Jeng MF, Campbell AP, Begley T, Holmgren A, Case DA, Wright PE, Dyson HJ. High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin. Structure (London, England : 1993). 2: 853-68. PMID 7812718 DOI: 10.1016/S0969-2126(94)00086-7 |
0.337 |
|
| 1995 |
Holmgren A. Thioredoxin structure and mechanism: conformational changes on oxidation of the active-site sulfhydryls to a disulfide Structure. 3: 239-243. PMID 7788289 DOI: 10.1016/S0969-2126(01)00153-8 |
0.385 |
|
| 1995 |
Martinez-Galisteo E, Padilla CA, Holmgren A, Bárcena JA. Characterization of mammalian thioredoxin reductase, thioredoxin and glutaredoxin by immunochemical methods. Comparative Biochemistry and Physiology B. 111: 17-25. PMID 7749633 DOI: 10.1016/0305-0491(94)00235-M |
0.324 |
|
| 1995 |
Björnstedt M, Hamberg M, Kumar S, Xue J, Holmgren A. Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols Journal of Biological Chemistry. 270: 11761-11764. PMID 7744824 DOI: 10.1074/Jbc.270.20.11761 |
0.343 |
|
| 1995 |
Lundström-Ljung J, Holmgren A. Glutaredoxin accelerates glutathione-dependent folding of reduced ribonuclease A together with protein disulfide-isomerase. Journal of Biological Chemistry. 270: 7822-7828. PMID 7713872 DOI: 10.1074/Jbc.270.14.7822 |
0.446 |
|
| 1995 |
Jeng M, Holmgren A, Dyson HJ. Proton sharing between cysteine thiols in Escherichia coli thioredoxin: implications for the mechanism of protein disulfide reduction. Biochemistry. 34: 10101-10105. PMID 7640264 DOI: 10.1021/Bi00032A001 |
0.405 |
|
| 1995 |
Spyrou G, Björnstedt M, Kumar S, Holmgren A. AP-1 DNA-binding activity is inhibited by selenite and selenodiglutathione Febs Letters. 368: 59-63. PMID 7615089 DOI: 10.1016/0014-5793(95)00599-5 |
0.312 |
|
| 1995 |
Wieles B, van Noort J, Drijfhout JW, Offringa R, Holmgren A, Ottenhoff TH. Purification and functional analysis of the Mycobacterium leprae thioredoxin/thioredoxin reductase hybrid protein. The Journal of Biological Chemistry. 270: 25604-6. PMID 7592733 DOI: 10.1074/Jbc.270.43.25604 |
0.361 |
|
| 1995 |
Rosén A, Lundman P, Carlsson M, Bhavani K, Srinivasa BR, Kjellström G, Nilsson K, Holmgren A. A CD4+ T cell line-secreted factor, growth promoting for normal and leukemic B cells, identified as thioredoxin International Immunology. 7: 625-633. PMID 7547690 DOI: 10.1093/Intimm/7.4.625 |
0.351 |
|
| 1995 |
Jornstedt MB, Kumar S, Holmgren A. [22] Selenite and selenodiglutathione: Reactions with thioredoxin systems Methods in Enzymology. 252: 209-219. PMID 7476355 DOI: 10.1016/0076-6879(95)52024-4 |
0.421 |
|
| 1995 |
Holmgren A, Bjornstedt M. [21] Thioredoxin and thioredoxin reductase Methods in Enzymology. 252: 199-208. PMID 7476354 DOI: 10.1016/0076-6879(95)52023-6 |
0.445 |
|
| 1995 |
Wieles B, van Soolingen D, Holmgren A, Offringa R, Ottenhoff T, Thole J. Unique gene organization of thioredoxin and thioredoxin reductase in Mycobacterium leprae. Molecular Microbiology. 16: 921-9. PMID 7476189 DOI: 10.1111/J.1365-2958.1995.Tb02318.X |
0.32 |
|
| 1994 |
Jane Dyson H, Jeng MF, Model P, Holmgren A. Characterization by 1H NMR of a C32S,C35S double mutant of Escherichia coli thioredoxin confirms its resemblance to the reduced wild-type protein Febs Letters. 339: 11-17. PMID 8313957 DOI: 10.1016/0014-5793(94)80375-7 |
0.369 |
|
| 1994 |
Bushweller JH, Billeter M, Holmgren A, Wüthrich K. The nuclear magnetic resonance solution structure of the mixed disulfide between Escherichia coli glutaredoxin(C14S) and glutathione. Journal of Molecular Biology. 235: 1585-97. PMID 8107093 DOI: 10.1006/Jmbi.1994.1108 |
0.341 |
|
| 1994 |
Chandrasekhar K, Campbell AP, Jeng M, Holmgren A, Dyson HJ. Effect of disulfide bridge formation on the NMR spectrum of a protein: Studies on oxidized and reduced Escherichia coli thioredoxin Journal of Biomolecular Nmr. 4: 411-432. PMID 8019144 DOI: 10.1007/Bf00179349 |
0.396 |
|
| 1994 |
Aslund F, Ehn B, Miranda-Vizuete A, Pueyo C, Holmgren A. Two additional glutaredoxins exist in Escherichia coli: glutaredoxin 3 is a hydrogen donor for ribonucleotide reductase in a thioredoxin/glutaredoxin 1 double mutant. Proceedings of the National Academy of Sciences of the United States of America. 91: 9813-9817. PMID 7937896 DOI: 10.1073/Pnas.91.21.9813 |
0.383 |
|
| 1993 |
Ren X, Björnstedt M, Shen B, Ericson ML, Holmgren A. Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione. Biochemistry. 32: 9701-8. PMID 8373774 DOI: 10.1021/Bi00088A023 |
0.371 |
|
| 1993 |
Xia TH, Bushweller JH, Sodano P, Billeter M, Björnberg O, Holmgren A, Wüthrich K. NMR structure of oxidized Escherichia coli glutaredoxin: comparison with reduced E. coli glutaredoxin and functionally related proteins. Protein Science : a Publication of the Protein Society. 1: 310-21. PMID 1304339 DOI: 10.1002/Pro.5560010302 |
0.384 |
|
| 1992 |
Soute BA, Groenen-van Dooren MM, Holmgren A, Lundström J, Vermeer C. Stimulation of the dithiol-dependent reductases in the vitamin K cycle by the thioredoxin system. Strong synergistic effects with protein disulphide-isomerase. The Biochemical Journal. 255-9. PMID 1731762 DOI: 10.1042/Bj2810255 |
0.319 |
|
| 1992 |
Padilla CA, Martínez-Galisteo E, López-Barea J, Holmgren A, Bárcena JA. Immunolocalization of thioredoxin and glutaredoxin in mammalian hypophysis. Molecular and Cellular Endocrinology. 85: 1-12. PMID 1526311 DOI: 10.1016/0303-7207(92)90119-Q |
0.332 |
|
| 1992 |
Kumar S, Björnstedt M, Holmgren A. Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen. Febs Journal. 207: 435-439. PMID 1321713 DOI: 10.1111/J.1432-1033.1992.Tb17068.X |
0.396 |
|
| 1991 |
Chandrasekhar K, Krause G, Holmgren A, Dyson HJ. Assignment of the 15N NMR spectra of reduced and oxidized Escherichia coli thioredoxin Febs Letters. 284: 178-183. PMID 2060637 DOI: 10.1016/0014-5793(91)80679-W |
0.326 |
|
| 1991 |
Eklund H, Gleason FK, Holmgren A. Structural and functional relations among thioredoxins of different species. Proteins. 11: 13-28. PMID 1961698 DOI: 10.1002/Prot.340110103 |
0.378 |
|
| 1991 |
Sodano P, Chary KV, Björnberg O, Holmgren A, Kren B, Fuchs JA, Wüthrich K. Nuclear magnetic resonance studies of recombinant Escherichia coli glutaredoxin. Sequence-specific assignments and secondary structure determination of the oxidized form. European Journal of Biochemistry. 200: 369-77. PMID 1889405 DOI: 10.1111/J.1432-1033.1991.Tb16194.X |
0.382 |
|
| 1991 |
Dyson HJ, Tennant LL, Holmgren A. Proton-transfer effects in the active-site region of Escherichia coli thioredoxin using two-dimensional 1H NMR. Biochemistry. 30: 4262-4268. PMID 1850621 DOI: 10.1021/Bi00231A023 |
0.307 |
|
| 1991 |
Björnberg O, Holmgren A. Characterization of homogeneous recombinant glutaredoxin from Escherichia coli: Purification from an inducible λPL expression system and properties of a novel elongated form Protein Expression and Purification. 2: 287-295. PMID 1821800 DOI: 10.1016/1046-5928(91)90085-W |
0.37 |
|
| 1991 |
Slaby I, Holmgren A. Rapid isolation of homogeneous cloned T7 gene 5 protein and T7 DNA polymerase by affinity chromatography on immobilized thioredoxin Protein Expression and Purification. 2: 270-277. PMID 1821798 DOI: 10.1016/1046-5928(91)90083-U |
0.329 |
|
| 1989 |
Dyson HJ, Holmgren A, Wright PE. Assignment of the proton NMR spectrum of reduced and oxidized thioredoxin: Sequence-specific assignments, secondary structure, and global fold Biochemistry. 28: 7074-7087. PMID 2684270 DOI: 10.1021/Bi00443A044 |
0.362 |
|
| 1989 |
Hansson H-, Holmgren A, Norstedt G, Rozell B. Changes in the distribution of insulin-like growth factor I, thioredoxin, thioredoxin reductase and ribonucleotide reductase during the development of the retina Experimental Eye Research. 48: 411-420. PMID 2647502 DOI: 10.1016/S0014-4835(89)80009-0 |
0.302 |
|
| 1988 |
Holmgren A. Thioredoxin and glutaredoxin: small multi-functional redox proteins with active-site disulphide bonds. Biochemical Society Transactions. 16: 95-96. PMID 3286320 DOI: 10.1042/Bst0160095 |
0.446 |
|
| 1988 |
Clement-Metral JD, Holmgren A, Cambillau C, Jörnvall H, Eklund H, Thomas D, Lederer F. Amino acid sequence determination and three-dimensional modelling of thioredoxin from the photosynthetic bacterium Rhodobacter sphaeroides Y. European Journal of Biochemistry. 172: 413-9. PMID 3280308 DOI: 10.1111/J.1432-1033.1988.Tb13902.X |
0.357 |
|
| 1988 |
Dyson HJ, Holmgren A, Wright PE. Structural differences between oxidized and reduced thioredoxin monitored by two-dimensional 1H NMR spectroscopy Febs Letters. 228: 254-258. PMID 3277863 DOI: 10.1016/0014-5793(88)80010-3 |
0.362 |
|
| 1988 |
Gleason FK, Holmgren A. Thioredoxin and related proteins in procaryotes Fems Microbiology Letters. 54: 271-297. PMID 3152490 DOI: 10.1111/J.1574-6968.1988.Tb02747.X |
0.439 |
|
| 1987 |
Johnson TC, Wada K, Buchanan BB, Holmgren A. Reduction of purothionin by the wheat seed thioredoxin system. Plant Physiology. 85: 446-51. PMID 16665718 DOI: 10.1104/Pp.85.2.446 |
0.38 |
|
| 1986 |
Höög J, Bahr-Lindström Hv, Jörnvall H, Holmgren A. Cloning and expression of the glutaredoxin (grx) gene of Escherichia coli. Gene. 43: 13-21. PMID 3530878 DOI: 10.1016/0378-1119(86)90003-X |
0.321 |
|
| 1986 |
Hansson HA, Holmgren A, Rozell B, Täljedal IB. Immunohistochemical localization of thioredoxin and thioredoxin reductase in mouse exocrine and endocrine pancreas. Cell and Tissue Research. 245: 189-195. PMID 3524849 DOI: 10.1007/Bf00218100 |
0.335 |
|
| 1986 |
Hansson H, Rozell B, Stemme S, Engström Y, Thelander L, Holmgren A. Different cellular distribution of thioredoxin and subunit M1 of ribonucleotide reductase in rat tissues. Experimental Cell Research. 163: 363-369. PMID 3514246 DOI: 10.1016/0014-4827(86)90067-4 |
0.311 |
|
| 1986 |
Clement‐Metral JD, Höög J, Holmgren A. Characterization of the thioredoxin system in the facultative phototroph Rhodobacter sphaeroides Y Febs Journal. 161: 119-126. PMID 2430804 DOI: 10.1111/J.1432-1033.1986.Tb10131.X |
0.402 |
|
| 1985 |
Holmgren A. [68] Glutaredoxin from Escherichia coli and calf thymus Methods in Enzymology. 113: 525-540. PMID 3911009 DOI: 10.1016/S0076-6879(85)13071-5 |
0.435 |
|
| 1984 |
Hessel B, Jörnvall H, Thorell L, Söderman S, Larsson U, Egberg N, Blombäck B, Holmgren A. Structure-function relationships of human factor VIII complex studied by thioredoxin dependent disulfide reduction. Thrombosis Research. 35: 637-51. PMID 6438823 DOI: 10.1016/0049-3848(84)90267-6 |
0.332 |
|
| 1984 |
Slaby I, Lind B, Holmgren A. T7 DNA polymerase is not a zinc-metalloenzyme and the polymerase and exonuclease activities are inhibited by zinc ions. Biochemical and Biophysical Research Communications. 122: 1410-1417. PMID 6433910 DOI: 10.1016/0006-291X(84)91248-8 |
0.323 |
|
| 1984 |
Holmgren A. Enzymatic reduction-oxidation of protein disulfides by thioredoxin Methods in Enzymology. 107: 295-300. PMID 6390091 DOI: 10.1016/0076-6879(84)07019-1 |
0.401 |
|
| 1984 |
Klintrot I, Hoog J, Jornvall H, Holmgren A, Luthman M. The primary structure of calf thymus glutaredoxin. Homology with the corresponding Escherichia coli protein but elongation at both ends and with an additional half-cystine/cysteine pair. Febs Journal. 144: 417-423. PMID 6386471 DOI: 10.1111/J.1432-1033.1984.Tb08481.X |
0.39 |
|
| 1984 |
Eklund H, Cambillau C, Sjöberg BM, Holmgren A, Jörnvall H, Höög JO, Brändén CI. Conformational and functional similarities between glutaredoxin and thioredoxins. The Embo Journal. 3: 1443-1449. DOI: 10.1002/J.1460-2075.1984.Tb01994.X |
0.331 |
|
| 1983 |
Höög J, Jörnvall H, Holmgren A, Carlquist M, Persson M. The primary structure of Escherichia coli glutaredoxin Febs Journal. 136: 223-232. PMID 6352262 DOI: 10.1111/J.1432-1033.1983.Tb07730.X |
0.412 |
|
| 1983 |
Höög J, Jörnvall H, Holmgren A, Carlquist M, Persson M. THE PRIMARY STRUCTURE OF Escherichia coli GLUTAREDOXIN DISTANT HOMOLOGY WITH THIOREDOXINS IN A SUPERFAMILY OF SMALL PROTEINS WITH A REDOX‐ACTIVE CYSTINE DISULFIDE/CYSTEINE DITHIOL Febs Journal. 136: 230-232. DOI: 10.1111/J.1432-1033.1983.Tb07731.X |
0.419 |
|
| 1982 |
Luthman M, Holmgren A. Rat liver thioredoxin and thioredoxin reductase: purification and characterization Biochemistry. 21: 6628-6633. PMID 7159551 DOI: 10.1021/Bi00269A003 |
0.356 |
|
| 1982 |
Höög J, Holmgren A, D'Silva C, Douglas KT, Seddon AP. Glutathione derivatives as inhibitors of glutaredoxin and ribonucleotides reductase from Escherichia coli Febs Letters. 138: 59-61. PMID 7040106 DOI: 10.1016/0014-5793(82)80394-3 |
0.316 |
|
| 1982 |
Höög J, Douglas KT, D'Silva C, Holmgren A. Photo-labelling of glutaredoxin from Escherichia coli Biochemical and Biophysical Research Communications. 107: 1475-1481. PMID 6753845 DOI: 10.1016/S0006-291X(82)80165-4 |
0.324 |
|
| 1982 |
Grankvist K, Holmgren A, Luthman M, Täljedal I. Thioredoxin and thioredoxin reductase in pancreatic islets may participate in diabetogenic free-radical production. Biochemical and Biophysical Research Communications. 107: 1412-1418. PMID 6753843 DOI: 10.1016/S0006-291X(82)80156-3 |
0.317 |
|
| 1981 |
Holmgren A. Regulation of ribonucleotide reductase. Current Topics in Cellular Regulation. 19: 47-76. PMID 7037315 DOI: 10.1016/B978-0-12-152819-5.50019-1 |
0.337 |
|
| 1981 |
Nygren H, Rozell B, Holmgren A, Hansson H. Immunoelectron microscopic localization of glutaredoxin and thioredoxin in Escherichia coli cells Febs Letters. 133: 145-150. PMID 7030783 DOI: 10.1016/0014-5793(81)80492-9 |
0.399 |
|
| 1981 |
Holmgren A. Selective N-bromosuccinimide oxidation of the nonfluorescent tryptophan-31 in the active center of thioredoxin from Escherichia coli. Biochemistry. 20: 3204-3207. PMID 7018569 DOI: 10.1021/Bi00514A033 |
0.374 |
|
| 1981 |
Holmgren A. Thioredoxin: structure and functions Trends in Biochemical Sciences. 6: 26-29. DOI: 10.1016/0968-0004(81)90010-4 |
0.388 |
|
| 1980 |
Holmgren A. Pyridine nucleotide - disulfide oxidoreductases. Experientia. Supplementum. 36: 149-180. PMID 6987076 DOI: 10.1007/978-3-0348-5419-1_5 |
0.406 |
|
| 1980 |
Holmgren A, Lyckeborg C. Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase Proceedings of the National Academy of Sciences of the United States of America. 77: 5149-5152. PMID 6933551 DOI: 10.1073/Pnas.77.9.5149 |
0.399 |
|
| 1979 |
Luthman M, Eriksson S, Holmgren A, Thelander L. Glutathione-dependent hydrogen donor system for calf thymus ribonucleoside-diphosphate reductase. Proceedings of the National Academy of Sciences of the United States of America. 76: 2158-2162. PMID 377293 DOI: 10.1073/Pnas.76.5.2158 |
0.431 |
|
| 1977 |
Holmgren A. The function of thioredoxin and glutathione in deoxyribonucleic acid synthesis. Biochemical Society Transactions. 5: 611-612. PMID 332555 DOI: 10.1042/Bst0050611 |
0.43 |
|
| 1976 |
Holmgren A, Morgan FJ. Enzymic Reduction of Disulfide Bonds by Thioredoxin Febs Journal. 70: 377-383. PMID 12950 DOI: 10.1111/J.1432-1033.1976.Tb11027.X |
0.327 |
|
| 1976 |
Holmgren A. Hydrogen donor system for Escherichia coli ribonucleoside-diphosphate reductase dependent upon glutathione Proceedings of the National Academy of Sciences of the United States of America. 73: 2275-2279. PMID 7783 DOI: 10.1073/Pnas.73.7.2275 |
0.367 |
|
| 1975 |
Holmgren A, Söderberg BO, Eklund H, Brändén CI. Three-dimensional structure of Escherichia coli thioredoxin-S2 to 2.8 A resolution. Proceedings of the National Academy of Sciences of the United States of America. 72: 2305-9. PMID 1094461 DOI: 10.1073/Pnas.72.6.2305 |
0.337 |
|
| 1974 |
Blombäck B, Blombäck M, Finkbeiner W, Holmgren A, Kowalska-Loth B, Olovson G. Enzymatic reduction of disulfide bonds in fibrin-ogen by the thioredoxin system. I. Identification of reduced bonds and studies on reoxidation process. Thrombosis Research. 4: 55-75. PMID 4151431 DOI: 10.1016/0049-3848(74)90203-5 |
0.343 |
|
| 1972 |
Holmgren A. Reversible chemical modification of the tryptophan residues of thioredoxin from Escherichia coli B. Febs Journal. 26: 528-534. PMID 4554572 DOI: 10.1111/J.1432-1033.1972.Tb01795.X |
0.378 |
|
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