Prashanth Rajarajan - Publications

Affiliations: 
Department of Neuroscience Icahn School of Medicine at Mount Sinai, New York, NY, United States 

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wahl N, Espeso-Gil S, Chietera P, Nagel A, Laighneach A, Morris DW, Rajarajan P, Akbarian S, Dechant G, Apostolova G. SATB2 organizes the 3D genome architecture of cognition in cortical neurons. Molecular Cell. PMID 38244545 DOI: 10.1016/j.molcel.2023.12.024  0.474
2023 Maury EA, Sherman MA, Genovese G, Gilgenast TG, Kamath T, Burris SJ, Rajarajan P, Flaherty E, Akbarian S, Chess A, McCarroll SA, Loh PR, Phillips-Cremins JE, Brennand KJ, Macosko EZ, et al. Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent and disruptions. Cell Genomics. 3: 100356. PMID 37601975 DOI: 10.1016/j.xgen.2023.100356  0.733
2021 Chandrasekaran S, Espeso-Gil S, Loh YE, Javidfar B, Kassim B, Zhu Y, Zhang Y, Dong Y, Bicks LK, Li H, Rajarajan P, Peter CJ, Sun D, Agullo-Pascual E, Iskhakova M, et al. Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions. Nature Communications. 12: 7243. PMID 34903713 DOI: 10.1038/s41467-021-26862-z  0.39
2020 Sey NYA, Hu B, Mah W, Fauni H, McAfee JC, Rajarajan P, Brennand KJ, Akbarian S, Won H. A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles. Nature Neuroscience. PMID 32152537 DOI: 10.1038/S41593-020-0603-0  0.672
2020 Espeso-Gil S, Halene T, Bendl J, Kassim B, Ben Hutta G, Iskhakova M, Shokrian N, Auluck P, Javidfar B, Rajarajan P, Chandrasekaran S, Peter CJ, Cote A, Birnbaum R, Liao W, et al. A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons. Genome Medicine. 12: 19. PMID 32075678 DOI: 10.1186/S13073-020-0715-X  0.487
2019 Rajarajan P, Akbarian S. Use of the epigenetic toolbox
to contextualize common variants associated with schizophrenia risk
. Dialogues in Clinical Neuroscience. 21: 407-416. PMID 31949408 DOI: 10.31887/Dcns.2019.21.4/Sakbarian  0.584
2019 Rajarajan P, Flaherty E, Akbarian S, Brennand KJ. CRISPR-based functional evaluation of schizophrenia risk variants. Schizophrenia Research. PMID 31277978 DOI: 10.1016/J.Schres.2019.06.017  0.771
2019 Rajarajan P, Borrman T, Liao W, Espeso-Gil S, Chandrasekaran S, Jiang Y, Weng Z, Brennand KJ, Akbarian S. Spatial genome exploration in the context of cognitive and neurological disease. Current Opinion in Neurobiology. 59: 112-119. PMID 31255842 DOI: 10.1016/J.Conb.2019.05.007  0.704
2018 Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, Powell S, Yashaswini C, LaMarca EA, Kassim B, Javidfar B, Espeso-Gil S, Li A, Won H, Geschwind DH, et al. Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk. Science (New York, N.Y.). 362. PMID 30545851 DOI: 10.1126/Science.Aat4311  0.649
2018 Boks MP, Houtepen LC, Xu Z, He Y, Ursini G, Maihofer AX, Rajarajan P, Yu Q, Xu H, Wu Y, Wang S, Shi JP, Hulshoff Pol HE, Strengman E, Rutten BPF, et al. Genetic vulnerability to DUSP22 promoter hypermethylation is involved in the relation between in utero famine exposure and schizophrenia. Npj Schizophrenia. 4: 16. PMID 30131491 DOI: 10.1038/S41537-018-0058-4  0.461
2018 Rajarajan P, Jiang Y, Kassim BS, Akbarian S. Chromosomal Conformations and Epigenomic Regulation in Schizophrenia. Progress in Molecular Biology and Translational Science. 157: 21-40. PMID 29933951 DOI: 10.1016/Bs.Pmbts.2017.11.022  0.593
2018 Boks M, Houtepen L, Xu Z, He Y, Ursini G, Maihofer A, Rajarajan P, Hulshoff Pol H, Rutten B, Jaffe AE, Kleinmann JE, Baker D, Hol E, Akbarian S, Nievergelt C, et al. O4.1. GENETIC VULNERABILITY TO DUSP22 PROMOTOR HYPERMETHYLATION IS INVOLVED IN THE RELATION BETWEEN IN UTERO FAMINE EXPOSURE AND SCHIZOPHRENIA Schizophrenia Bulletin. 44: S82-S82. DOI: 10.1093/Schbul/Sby015.207  0.505
2017 Ho SM, Hartley BJ, Flaherty E, Rajarajan P, Abdelaal R, Obiorah I, Barretto N, Muhammad H, Phatnani HP, Akbarian S, Brennand KJ. Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes. Stem Cell Reports. PMID 28757163 DOI: 10.1016/J.Stemcr.2017.06.012  0.698
2017 Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, et al. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature Genetics. PMID 28671686 DOI: 10.1038/Ng.3906  0.763
2016 Rajarajan P, Gil SE, Brennand KJ, Akbarian S. Spatial genome organization and cognition. Nature Reviews. Neuroscience. PMID 27708356 DOI: 10.1038/Nrn.2016.124  0.652
2015 Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, et al. Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients. Translational Psychiatry. 5: e662. PMID 26485546 DOI: 10.1038/Tp.2015.118  0.741
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