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Thu Thuy T Dang - Publications

Affiliations: 
Chemistry University of British Columbia, Okanagan 
Area:
biosynthesis of natural products, biological chemistry, cytochrome P450s
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Stander EA, Lehka B, Carqueijeiro I, Cuello C, Hansson FG, Jansen HJ, Dugé De Bernonville T, Birer Williams C, Vergès V, Lezin E, Lorensen MDBB, Dang TT, Oudin A, Lanoue A, Durand M, et al. The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids. Communications Biology. 6: 1197. PMID 38001233 DOI: 10.1038/s42003-023-05574-8  0.403
2023 Bui VH, Rodríguez-López CE, Dang TT. Integration of discovery and engineering in plant alkaloid research: Recent developments in elucidation, reconstruction, and repurposing biosynthetic pathways. Current Opinion in Plant Biology. 74: 102379. PMID 37182414 DOI: 10.1016/j.pbi.2023.102379  0.516
2023 Nguyen TM, Grzech D, Chung K, Xia Z, Nguyen TD, Dang TT. Discovery of a cytochrome P450 enzyme catalyzing the formation of spirooxindole alkaloid scaffold. Frontiers in Plant Science. 14: 1125158. PMID 36818833 DOI: 10.3389/fpls.2023.1125158  0.49
2023 Kwan BD, Seligmann B, Nguyen TD, Franke J, Dang TT. Leveraging synthetic biology and metabolic engineering to overcome obstacles in plant pathway elucidation. Current Opinion in Plant Biology. 71: 102330. PMID 36599248 DOI: 10.1016/j.pbi.2022.102330  0.771
2022 Nguyen TM, McConnachie M, Nguyen TD, Dang TT. Discovery and Characterization of Oxidative Enzymes Involved in Monoterpenoid Indole Alkaloid Biosynthesis. Methods in Molecular Biology (Clifton, N.J.). 2505: 141-164. PMID 35732943 DOI: 10.1007/978-1-0716-2349-7_11  0.502
2021 Nguyen TM, Nguyen TD, Leung YY, McConnachie M, Sannikov O, Xia Z, Dang TT. Discovering and harnessing oxidative enzymes for chemoenzymatic synthesis and diversification of anticancer camptothecin analogues. Communications Chemistry. 4: 177. PMID 36697859 DOI: 10.1038/s42004-021-00602-2  0.371
2021 Franke J, Zhang Y, Dang TT. Editorial: Exploring and Engineering Plant Specialized Metabolism: Latest Advances and New Horizons. Frontiers in Plant Science. 12: 783465. PMID 34777454 DOI: 10.3389/fpls.2021.783465  0.727
2021 Nguyen TD, Dang TT. Cytochrome P450 Enzymes as Key Drivers of Alkaloid Chemical Diversification in Plants. Frontiers in Plant Science. 12: 682181. PMID 34367208 DOI: 10.3389/fpls.2021.682181  0.568
2021 Nguyen T, Dang TT. Cytochrome P450 Enzymes as Key Drivers of Alkaloid Chemical Diversification in Plants Frontiers in Plant Science. 12. DOI: 10.3389/fpls.2021.682181  0.553
2018 Dang TT, Franke J, Carqueijeiro IST, Langley C, Courdavault V, O'Connor SE. Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes. Nature Chemical Biology. PMID 29942076 DOI: 10.1038/S41589-018-0078-4  0.768
2018 Carqueijeiro IT, Brown S, Chung K, Dang TT, Walia M, Besseau S, Dugé de Bernonville T, Oudin A, Lanoue A, Billet K, Munsch T, Koudounas K, Melin C, Godon C, Razafimandimby B, et al. Two tabersonine 6,7-epoxidases start synthesis of lochnericine-type alkaloids in Catharanthus roseus. Plant Physiology. PMID 29934299 DOI: 10.1104/Pp.18.00549  0.687
2018 Caputi L, Franke J, Farrow SC, Chung K, Payne RME, Nguyen TD, Dang TT, Soares Teto Carqueijeiro I, Koudounas K, Dugé de Bernonville T, Ameyaw B, Jones DM, Vieira IJC, Courdavault V, O'Connor SE. Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle. Science (New York, N.Y.). PMID 29724909 DOI: 10.1126/Science.Aat4100  0.77
2018 Carqueijeiro I, Dugé de Bernonville T, Lanoue A, Dang TT, Teijaro C, Paetz C, Billet K, Mosquera A, Oudin A, Besseau S, Papon N, Glévarec G, Atehortùa L, Clastre M, Giglioli-Guivarc'h N, et al. A BAHD acyltransferase catalyzing 19-O-acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids. The Plant Journal : For Cell and Molecular Biology. PMID 29438577 DOI: 10.1111/Tpj.13868  0.642
2018 Stavrinides A, Tatsis E, Dang TT, Caputi L, Stevenson C, Lawson D, Schneider B, O'Connor S. Discovery of a short chain dehydrogenase from Catharanthus roseus that produces a novel monoterpene indole alkaloid. Chembiochem : a European Journal of Chemical Biology. PMID 29424954 DOI: 10.1002/Cbic.201700621  0.765
2017 Tatsis EC, Carqueijeiro I, Dugé de Bernonville T, Franke J, Dang TT, Oudin A, Lanoue A, Lafontaine F, Stavrinides AK, Clastre M, Courdavault V, O'Connor SE. A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate. Nature Communications. 8: 316. PMID 28827772 DOI: 10.1038/S41467-017-00154-X  0.713
2017 Dang TT, Franke J, Tatsis EC, O'Connor SE. Dual catalytic activity of a cytochrome P450 controls bifurcation at a metabolic branch point of alkaloid biosynthesis in Rauwolfia serpentina. Angewandte Chemie (International Ed. in English). PMID 28654178 DOI: 10.1002/Anie.201705010  0.729
2015 Chen X, Dang TT, Facchini PJ. Noscapine comes of age. Phytochemistry. 111: 7-13. PMID 25583437 DOI: 10.1016/J.Phytochem.2014.09.008  0.702
2015 Dang TT, Chen X, Facchini PJ. Acetylation serves as a protective group in noscapine biosynthesis in opium poppy. Nature Chemical Biology. 11: 104-6. PMID 25485687 DOI: 10.1038/Nchembio.1717  0.555
2014 Dang TT, Facchini PJ. CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy. The Journal of Biological Chemistry. 289: 2013-26. PMID 24324259 DOI: 10.1074/Jbc.M113.505099  0.617
2014 Dang TT, Facchini PJ. Cloning and characterization of canadine synthase involved in noscapine biosynthesis in opium poppy. Febs Letters. 588: 198-204. PMID 24316226 DOI: 10.1016/J.Febslet.2013.11.037  0.578
2012 Dang TT, Onoyovwi A, Farrow SC, Facchini PJ. Biochemical genomics for gene discovery in benzylisoquinoline alkaloid biosynthesis in opium poppy and related species. Methods in Enzymology. 515: 231-66. PMID 22999177 DOI: 10.1016/B978-0-12-394290-6.00011-2  0.648
2012 Dang TT, Facchini PJ. Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy. Plant Physiology. 159: 618-31. PMID 22535422 DOI: 10.1104/Pp.112.194886  0.556
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