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Philippe Bastiaens, PhD - Publications

Affiliations: 
1993-1996 Max Planck Institute for Biophysical Chemistry, Göttingen, Göttingen, Niedersachsen, Germany 
 1997-1999 Imperial Cancer Research Fund 
 2000-2005 EMBL, Heidelberg 
 2006- Systemic Cell Biology Max Planck Institute of Molcular Physisology 
Area:
signaling, biochemistry, microscopy
Website:
https://www.mpi-dortmund.mpg.de/institute/directors/philippe-bastiaens
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59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Joshi MS, Stanoev A, Huebinger J, Soetje B, Zorina V, Roßmannek L, Michel K, Müller SA, Bastiaens PI. The EGFR phosphatase RPTPγ is a redox-regulated suppressor of promigratory signaling. The Embo Journal. e111806. PMID 36988334 DOI: 10.15252/embj.2022111806  0.356
2021 Brüggemann Y, Karajannis LS, Stanoev A, Stallaert W, Bastiaens PIH. Growth factor-dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools. Science Signaling. 14. PMID 34006609 DOI: 10.1126/scisignal.abd9943  0.719
2020 Koseska A, Bastiaens PIH. Processing Temporal Growth Factor Patterns by an Epidermal Growth Factor Receptor Network Dynamically Established in Space. Annual Review of Cell and Developmental Biology. 36: 359-383. PMID 32692593 DOI: 10.1146/annurev-cellbio-013020-103810  0.374
2019 Garivet G, Hofer W, Konitsiotis A, Klein C, Kaiser N, Mejuch T, Fansa E, Alsaabi R, Wittinghofer A, Bastiaens PIH, Waldmann H. Small-Molecule Inhibition of the UNC-Src Interaction Impairs Dynamic Src Localization in Cells. Cell Chemical Biology. PMID 30956149 DOI: 10.1016/J.Chembiol.2019.02.019  0.33
2018 Baumdick M, Gelléri M, Uttamapinant C, Beránek V, Chin JW, Bastiaens PIH. A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation. Nature Communications. 9: 3847. PMID 30242154 DOI: 10.1038/S41467-018-06299-7  0.321
2018 Corbat AA, Schuermann KC, Liguzinski P, Radon Y, Bastiaens PIH, Verveer PJ, Grecco HE. Co-imaging extrinsic, intrinsic and effector caspase activity by fluorescence anisotropy microscopy. Redox Biology. 19: 210-217. PMID 30176560 DOI: 10.1016/j.redox.2018.07.023  0.341
2018 Stanoev A, Mhamane A, Schuermann KC, Grecco HE, Stallaert W, Baumdick M, Brüggemann Y, Joshi MS, Roda-Navarro P, Fengler S, Stockert R, Roßmannek L, Luig J, Koseska A, Bastiaens PIH. Interdependence between EGFR and Phosphatases Spatially Established by Vesicular Dynamics Generates a Growth Factor Sensing and Responding Network. Cell Systems. PMID 30145116 DOI: 10.1016/j.cels.2018.06.006  0.713
2018 Stallaert W, Brüggemann Y, Sabet O, Baak L, Gattiglio M, Bastiaens PIH. Contact inhibitory Eph signaling suppresses EGF-promoted cell migration by decoupling EGFR activity from vesicular recycling. Science Signaling. 11. PMID 30065026 DOI: 10.1126/scisignal.aat0114  0.715
2017 Konitsiotis AD, Roßmannek L, Stanoev A, Schmick M, Bastiaens PIH. Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation. Nature Communications. 8: 114. PMID 28740133 DOI: 10.1038/s41467-017-00116-3  0.332
2017 Huebinger J, Masip ME, Christmann J, Wehner F, Bastiaens PIH. Reversible Cryo-arrests of Living Cells to Pause Molecular Movements for High-resolution Imaging. Bio-Protocol. 7. PMID 28580376 DOI: 10.21769/BioProtoc.2236  0.328
2016 Masip ME, Huebinger J, Christmann J, Sabet O, Wehner F, Konitsiotis A, Fuhr GR, Bastiaens PIH. Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution. Nature Methods. 13: 665-672. PMID 27400419 DOI: 10.1038/nmeth.3921  0.378
2016 Robinson T, Kubsch B, Bastiaens P, Lipowsky R, Dimova R. Membrane Fusion via Snare Mimetics Spatially Confined to Intramembrane Domains Biophysical Journal. 110: 249a-250a. DOI: 10.1016/J.Bpj.2015.11.1373  0.318
2015 Baumdick M, Brüggemann Y, Schmick M, Xouri G, Sabet O, Davis L, Chin JW, Bastiaens PI. EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling. Elife. 4. PMID 26609808 DOI: 10.7554/Elife.12223  0.364
2015 Ibach J, Radon Y, Gelléri M, Sonntag MH, Brunsveld L, Bastiaens PI, Verveer PJ. Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits. Plos One. 10: e0143162. PMID 26575183 DOI: 10.1371/journal.pone.0143162  0.345
2015 Sabet O, Stockert R, Xouri G, Brüggemann Y, Stanoev A, Bastiaens PIH. Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode. Nature Communications. 6: 8047. PMID 26292967 DOI: 10.1038/ncomms9047  0.349
2014 Roda-Navarro P, Bastiaens PI. Dynamic recruitment of protein tyrosine phosphatase PTPD1 to EGF stimulation sites potentiates EGFR activation. Plos One. 9: e103203. PMID 25062045 DOI: 10.1371/journal.pone.0103203  0.383
2014 Vartak N, Papke B, Grecco HE, Rossmannek L, Waldmann H, Hedberg C, Bastiaens PI. The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins. Biophysical Journal. 106: 93-105. PMID 24411241 DOI: 10.1016/J.Bpj.2013.11.024  0.326
2013 Symeonidou IE, Kotsantis P, Roukos V, Rapsomaniki MA, Grecco HE, Bastiaens P, Taraviras S, Lygerou Z. Multi-step Loading of Human Minichromosome Maintenance Proteins in Live Human Cells Journal of Biological Chemistry. 288: 35852-35867. PMID 24158436 DOI: 10.1074/Jbc.M113.474825  0.343
2013 Grecco HE, Bastiaens PI. Quantifying cellular dynamics by fluorescence resonance energy transfer (FRET) microscopy. Current Protocols in Neuroscience. Unit5.22. PMID 23559306 DOI: 10.1002/0471142301.ns0522s63  0.388
2013 Gandor S, Reisewitz S, Venkatachalapathy M, Arrabito G, Reibner M, Schröder H, Ruf K, Niemeyer CM, Bastiaens PI, Dehmelt L. A protein-interaction array inside a living cell. Angewandte Chemie (International Ed. in English). 52: 4790-4. PMID 23460583 DOI: 10.1002/Anie.201209127  0.354
2013 Blümer J, Rey J, Dehmelt L, Mazel T, Wu YW, Bastiaens P, Goody RS, Itzen A. RabGEFs are a major determinant for specific Rab membrane targeting. The Journal of Cell Biology. 200: 287-300. PMID 23382462 DOI: 10.1083/Jcb.201209113  0.339
2013 Berg V, Vartak N, Claus R, Claasen J, Rusch M, Pallasch CP, Waldmann H, Plass C, Bastiaens P, Hallek M, Hedberg C, Wendtner C, Frenzel LP. A Complex Molecular Network Controls Palmitoylation-Dependant CD95 Sensitivity Of CLL Cells Blood. 122: 4148-4148. DOI: 10.1182/Blood.V122.21.4148.4148  0.309
2012 Haj FG, Sabet O, Kinkhabwala A, Wimmer-Kleikamp S, Roukos V, Han HM, Grabenbauer M, Bierbaum M, Antony C, Neel BG, Bastiaens PI. Regulation of signaling at regions of cell-cell contact by endoplasmic reticulum-bound protein-tyrosine phosphatase 1B. Plos One. 7: e36633. PMID 22655028 DOI: 10.1371/journal.pone.0036633  0.321
2012 Milroy LG, Rizzo S, Calderon A, Ellinger B, Erdmann S, Mondry J, Verveer P, Bastiaens P, Waldmann H, Dehmelt L, Arndt HD. Selective chemical imaging of static actin in live cells. Journal of the American Chemical Society. 134: 8480-6. PMID 22475347 DOI: 10.1021/Ja211708Z  0.311
2010 Nievergall E, Janes PW, Stegmayer C, Vail ME, Haj FG, Teng SW, Neel BG, Bastiaens PI, Lackmann M. PTP1B regulates Eph receptor function and trafficking. The Journal of Cell Biology. 191: 1189-203. PMID 21135139 DOI: 10.1083/Jcb.201005035  0.385
2010 Vartak N, Bastiaens P. Spatial cycles in G‐protein crowd control The Embo Journal. 29: 2689-2699. PMID 20717139 DOI: 10.1038/Emboj.2010.184  0.461
2010 Grecco HE, Roda-Navarro P, Girod A, Hou J, Frahm T, Truxius DC, Pepperkok R, Squire A, Bastiaens PI. In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays. Nature Methods. 7: 467-72. PMID 20453867 DOI: 10.1038/nmeth.1458  0.412
2010 Zamir E, Lommerse PH, Kinkhabwala A, Grecco HE, Bastiaens PI. Fluorescence fluctuations of quantum-dot sensors capture intracellular protein interaction dynamics. Nature Methods. 7: 295-8. PMID 20228813 DOI: 10.1038/nmeth.1441  0.35
2009 Janes PW, Wimmer-Kleikamp SH, Frangakis AS, Treble K, Griesshaber B, Sabet O, Grabenbauer M, Ting AY, Saftig P, Bastiaens PI, Lackmann M. Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10. Plos Biology. 7: e1000215. PMID 19823572 DOI: 10.1371/journal.pbio.1000215  0.319
2009 Bastiaens P. Systems Biology: When it is time to die Nature. 459: 334-335. PMID 19458703 DOI: 10.1038/459334A  0.305
2008 Offterdinger M, Bastiaens PI. Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane. Traffic (Copenhagen, Denmark). 9: 147-55. PMID 17956594 DOI: 10.1111/j.1600-0854.2007.00665.x  0.354
2007 Maeder CI, Hink MA, Kinkhabwala A, Mayr R, Bastiaens PI, Knop M. Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling. Nature Cell Biology. 9: 1319-26. PMID 17952059 DOI: 10.1038/Ncb1652  0.366
2007 Bastiaens P. Pimp my cell Molecular Systems Biology. 3: 120-120. PMID 17593908 DOI: 10.1038/Msb4100164  0.389
2007 Niethammer P, Kronja I, Kandels-Lewis S, Rybina S, Bastiaens P, Karsenti E. Discrete states of a protein interaction network govern interphase and mitotic microtubule dynamics. Plos Biology. 5: e29. PMID 17227146 DOI: 10.1371/Journal.Pbio.0050029  0.377
2007 Yudushkin IA, Schleifenbaum A, Kinkhabwala A, Neel BG, Schultz C, Bastiaens PI. Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B. Science (New York, N.Y.). 315: 115-9. PMID 17204654 DOI: 10.1126/science.1134966  0.424
2006 Verveer PJ, Rocks O, Harpur AG, Bastiaens PI. Imaging protein interactions by FRET microscopy: cell preparation for FRET analysis. Csh Protocols. 2006. PMID 22485994 DOI: 10.1101/pdb.prot4646  0.327
2006 Verveer PJ, Rocks O, Harpur AG, Bastiaens PI. Imaging protein interactions by FRET microscopy: labeling proteins with fluorescent dyes. Csh Protocols. 2006. PMID 22485993 DOI: 10.1101/pdb.prot4645  0.309
2006 Verveer PJ, Rocks O, Harpur AG, Bastiaens PI. Imaging protein interactions by FRET microscopy: FLIM measurements. Csh Protocols. 2006. PMID 22485986 DOI: 10.1101/pdb.prot4599  0.318
2006 Verveer PJ, Rocks O, Harpur AG, Bastiaens PI. Imaging protein interactions by FRET microscopy: FRET measurements by acceptor photobleaching. Csh Protocols. 2006. PMID 22485985 DOI: 10.1101/pdb.prot4598  0.305
2006 Wouters FS, Bastiaens PI. Imaging protein-protein interactions by Fluorescence Resonance Energy Transfer (FRET) microscopy. Current Protocols in Neuroscience. Unit 5.22. PMID 18428638 DOI: 10.1002/0471142301.ns0522s34  0.669
2006 Bastiaens P, Caudron M, Niethammer P, Karsenti E. Gradients in the self-organization of the mitotic spindle. Trends in Cell Biology. 16: 125-34. PMID 16478663 DOI: 10.1016/J.Tcb.2006.01.005  0.322
2005 Keese M, Magdeburg RJ, Herzog T, Hasenberg T, Offterdinger M, Pepperkok R, Sturm JW, Bastiaens PI. Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues. The Journal of Biological Chemistry. 280: 27826-31. PMID 15908435 DOI: 10.1074/jbc.M504485200  0.381
2005 Peyker A, Rocks O, Bastiaens PI. Imaging activation of two Ras isoforms simultaneously in a single cell. Chembiochem : a European Journal of Chemical Biology. 6: 78-85. PMID 15637661 DOI: 10.1002/cbic.200400280  0.389
2004 Offterdinger M, Georget V, Girod A, Bastiaens PI. Imaging phosphorylation dynamics of the epidermal growth factor receptor. The Journal of Biological Chemistry. 279: 36972-81. PMID 15215236 DOI: 10.1074/jbc.M405830200  0.431
2004 Squire A, Verveer PJ, Rocks O, Bastiaens PI. Red-edge anisotropy microscopy enables dynamic imaging of homo-FRET between green fluorescent proteins in cells. Journal of Structural Biology. 147: 62-9. PMID 15109606 DOI: 10.1016/j.jsb.2003.10.013  0.333
2004 Niethammer P, Bastiaens P, Karsenti E. Stathmin-tubulin interaction gradients in motile and mitotic cells. Science (New York, N.Y.). 303: 1862-6. PMID 15031504 DOI: 10.1126/Science.1094108  0.407
2003 Reynolds AR, Tischer C, Verveer PJ, Rocks O, Bastiaens PI. EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation. Nature Cell Biology. 5: 447-53. PMID 12717446 DOI: 10.1038/ncb981  0.407
2001 Wouters FS, Bastiaens PIH. Imaging protein-protein interactions by Fluorescence Resonance Energy Transfer (FRET) microscopy. Current Protocols in Protein Science. 23. PMID 18429146 DOI: 10.1002/0471140864.Ps1905S23  0.665
2001 Verveer PJ, Squire A, Bastiaens PI. Improved spatial discrimination of protein reaction states in cells by global analysis and deconvolution of fluorescence lifetime imaging microscopy data. Journal of Microscopy. 202: 451-6. PMID 11422665 DOI: 10.1046/j.1365-2818.2001.00917.x  0.341
2001 Wouters FS, Verveer PJ, Bastiaens PIH. Imaging biochemistry inside cells Trends in Cell Biology. 11: 203-211. PMID 11316609 DOI: 10.1016/S0962-8924(01)01982-1  0.676
2001 Bastiaens PI, Pepperkok R. Observing proteins in their natural habitat: the living cell. Trends in Biochemical Sciences. 25: 631-7. PMID 11116191 DOI: 10.1016/S0968-0004(00)01714-X  0.365
2000 Wouters FS, Bastiaens PIH. Imaging protein-protein interactions by fluorescence resonance energy transfer (FRET) microscopy. Current Protocols in Pharmacology. 7. PMID 18228337 DOI: 10.1002/0471143030.Cb1701S07  0.669
2000 Verveer PJ, Wouters FS, Reynolds AR, Bastiaens PI. Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane. Science (New York, N.Y.). 290: 1567-70. PMID 11090353 DOI: 10.1126/SCIENCE.290.5496.1567  0.699
2000 Wouters FS, Bastiaens PI. Fluorescence lifetime imaging of receptor tyrosine kinase activity in cells. Current Biology : Cb. 9: 1127-30. PMID 10531012 DOI: 10.1016/S0960-9822(99)80484-9  0.711
1999 Ng T, Squire A, Hansra G, Bornancin F, Prevostel C, Hanby A, Harris W, Barnes D, Schmidt S, Mellor H, Bastiaens PI, Parker PJ. Imaging protein kinase Calpha activation in cells. Science (New York, N.Y.). 283: 2085-9. PMID 10092232 DOI: 10.1126/Science.283.5410.2085  0.429
1999 Bastiaens PI, Squire A. Fluorescence lifetime imaging microscopy: spatial resolution of biochemical processes in the cell. Trends in Cell Biology. 9: 48-52. PMID 10087617 DOI: 10.1016/S0962-8924(98)01410-X  0.316
1998 Wouters FS, Bastiaens PI, Wirtz KW, Jovin TM. FRET microscopy demonstrates molecular association of non-specific lipid transfer protein (nsL-TP) with fatty acid oxidation enzymes in peroxisomes. The Embo Journal. 17: 7179-89. PMID 9857175 DOI: 10.1093/Emboj/17.24.7179  0.661
1996 Bastiaens PI, Jovin TM. Microspectroscopic imaging tracks the intracellular processing of a signal transduction protein: fluorescent-labeled protein kinase C beta I. Proceedings of the National Academy of Sciences of the United States of America. 93: 8407-12. PMID 8710884 DOI: 10.1073/PNAS.93.16.8407  0.591
1994 Bastiaens PI, Pap EH, Widengren J, Rigler R, Visser AJ. Fluorescence methods to study lipid-protein association: The interaction of protein kinase C with lipid-loaded mixed micelles. Journal of Fluorescence. 4: 377-83. PMID 24233621 DOI: 10.1007/Bf01881462  0.363
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