Norman Metanis, Ph. D. - Publications

Affiliations: 
Institute of Chemistry Hebrew University, Jerusalem, Jerusalem, Israel 

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Weil-Ktorza O, Dhayalan B, Chen YS, Weiss MA, Metanis N. Se-Glargine : Chemical Synthesis of a Basal Insulin Analogue Stabilized by an Internal Diselenide Bridge. Chembiochem : a European Journal of Chemical Biology. e202300818. PMID 38149322 DOI: 10.1002/cbic.202300818  0.342
2022 Zhao Z, Mousa R, Metanis N. One-Pot Chemical Protein Synthesis Utilizing Fmoc-Masked Selenazolidine to Address the Redox Functionality of Human Selenoprotein F. Chemistry (Weinheim An Der Bergstrasse, Germany). e202200279. PMID 35112407 DOI: 10.1002/chem.202200279  0.771
2021 Mousa R, Hidmi T, Pomyalov S, Lansky S, Khouri L, Shalev DE, Shoham G, Metanis N. Diselenide crosslinks for enhanced and simplified oxidative protein folding. Communications Chemistry. 4: 30. PMID 36697775 DOI: 10.1038/s42004-021-00463-9  0.467
2021 Zhao Z, Shimon D, Metanis N. Chemoselective Copper-Mediated Modification of Selenocysteines in Peptides and Proteins. Journal of the American Chemical Society. PMID 34346673 DOI: 10.1021/jacs.1c06101  0.772
2020 Longo LM, Despotović D, Weil-Ktorza O, Walker MJ, Jabłońska J, Fridmann-Sirkis Y, Varani G, Metanis N, Tawfik DS. Primordial emergence of a nucleic acid-binding protein via phase separation and statistical ornithine-to-arginine conversion. Proceedings of the National Academy of Sciences of the United States of America. PMID 32561643 DOI: 10.1073/Pnas.2001989117  0.434
2020 Lahav N, Rotem-Bamberger S, Fahoum J, Dodson EJ, Kraus Y, Mousa R, Metanis N, Friedler A, Schueler-Furman O. Phosphorylation of the WWOX protein regulates its interaction with p73. Chembiochem : a European Journal of Chemical Biology. PMID 32185845 DOI: 10.1002/Cbic.202000032  0.31
2020 Metanis N, Ghareeb H. The Thioredoxin System: a Promising Target for Cancer Drug Development. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32097513 DOI: 10.1002/Chem.201905792  0.342
2020 Notis Dardashti R, Kumar S, Sternisha S, Post SR, Miller BG, Metanis N. Selenolysine: a new tool for traceless isopeptide bond formation. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31960982 DOI: 10.1002/Chem.202000310  0.598
2020 Weiss M, Dhayalan B, Chen YS, Phillips N, Swain M, Rege N, Mirsalehi A, Jarosinski M, Ismail-Beigi F, Metanis N. Reassessment of an Innovative Insulin Analogue Excludes Protracted Action yet Highlights Distinction between External and Internal Diselenide Bridges. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31958351 DOI: 10.1002/Chem.202000309  0.339
2019 Zhao Z, Metanis N. Utilizing copper-mediated deprotection of selenazolidine for cyclic peptides synthesis. The Journal of Organic Chemistry. PMID 31875677 DOI: 10.1021/Acs.Joc.9B02644.S001  0.761
2019 Samarasimhareddy M, Mayer D, Metanis N, Veprintsev D, Hurevich M, Friedler A. A targeted approach for the synthesis of multi-phosphorylated peptides: a tool for studying the role of phosphorylation patterns in proteins. Organic & Biomolecular Chemistry. PMID 31497840 DOI: 10.1039/C9Ob01874C  0.456
2019 Zhao Z, Metanis N. Copper-mediated selenazolidine deprotection enables one-pot chemical synthesis of challenging proteins. Angewandte Chemie (International Ed. in English). PMID 31408267 DOI: 10.1002/Anie.201909484  0.776
2019 Metanis N, Notis Dardashti R, Mousa R, Weil-Ktorza O. Miklós Bodanszky Award Lecture: Selective chalcogen chemistry to study protein science. Journal of Peptide Science : An Official Publication of the European Peptide Society. 25: e3204. PMID 31407415 DOI: 10.1002/Psc.3204  0.551
2019 Weil-Ktorza O, Rege N, Lansky S, Shalev DE, Shoham G, Weiss MA, Metanis N. Substitution of an Internal Disulfide Bridge in Human Insulin by a Diselenide Enhances its Foldability and Stability. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31012517 DOI: 10.1002/Chem.201900892  0.324
2019 Abbasi R, Mousa R, Dekel N, Amartely H, Danieli T, Lebendiker M, Levi‐Kalisman Y, Shalev DE, Metanis N, Chai L. Cover Feature: The Bacterial Extracellular Matrix Protein TapA Is a Two‐Domain Partially Disordered Protein (ChemBioChem 3/2019) Chembiochem. 20: 310-310. DOI: 10.1002/Cbic.201900009  0.381
2018 Mousa R, Lansky S, Shoham G, Metanis N. BPTI folding revisited: switching a disulfide into methylene thioacetal reveals a previously hidden path. Chemical Science. 9: 4814-4820. PMID 29910933 DOI: 10.1039/c8sc01110a  0.451
2017 Metanis N, Mousa R, Notis Dardashti R. Selenium and Selenocysteine in Protein Chemistry. Angewandte Chemie (International Ed. in English). PMID 28857389 DOI: 10.1002/Anie.201706876  0.512
2017 Dardashti RN, Metanis N. Revisiting ligation at selenomethionine: Insights into native chemical ligation at selenocysteine and homoselenocysteine. Bioorganic & Medicinal Chemistry. PMID 28526476 DOI: 10.1016/J.Bmc.2017.05.006  0.529
2017 Dery L, Reddy PS, Dery S, Mousa R, Ktorza O, Talhami A, Metanis N. Accessing human selenoproteins through chemical protein synthesis. Chemical Science. 8: 1922-1926. PMID 28451306 DOI: 10.1039/C6Sc04123J  0.511
2017 Chandra K, Das P, Metanis N, Friedler A, Reches M. Peptide fibrils as monomer storage of the covalent HIV-1 integrase inhibitor. Journal of Peptide Science : An Official Publication of the European Peptide Society. PMID 28070909 DOI: 10.1002/Psc.2959  0.418
2017 Mousa R, Reddy PS, Metanis N. Chemical Protein Synthesis through Selenocysteine Chemistry Synlett. 28: 1389-1393. DOI: 10.1055/S-0036-1588762  0.535
2016 Shoshan MS, Lehman Y, Goch W, Bal W, Tshuva EY, Metanis N. Selenocysteine containing analogues of Atx1-based peptides protect cells from copper ion toxicity. Organic & Biomolecular Chemistry. PMID 27349676 DOI: 10.1039/C6Ob00849F  0.428
2016 Chandra K, Das P, Mamidi S, Hurevich M, Iosub-Amir A, Metanis N, Reches M, Friedler A. Covalent Inhibition of HIV-1 Integrase by N-Succinimidyl Peptides. Chemmedchem. PMID 27331774 DOI: 10.1002/Cmdc.201600190  0.45
2016 Sai Reddy P, Metanis N. Small molecule diselenide additives for in vitro oxidative protein folding. Chemical Communications (Cambridge, England). PMID 26822519 DOI: 10.1039/C5Cc10451C  0.492
2016 Chandra K, Das P, Mamidi S, Hurevich M, Iosub-Amir A, Metanis N, Reches M, Friedler A. Cover Picture: Covalent Inhibition of HIV-1 Integrase by N-Succinimidyl Peptides (ChemMedChem 18/2016) Chemmedchem. 11: 1969. DOI: 10.1002/Cmdc.201600435  0.315
2015 Dery S, Reddy PS, Dery L, Mousa R, Dardashti RN, Metanis N. Insights into the deselenization of selenocysteine into alanine and serine. Chemical Science. 6: 6207-6212. PMID 30090236 DOI: 10.1039/C5Sc02528A  0.398
2015 Metanis N, Hilvert D. Harnessing selenocysteine reactivity for oxidative protein folding. Chemical Science. 6: 322-325. PMID 28757941 DOI: 10.1039/C4Sc02379J  0.634
2015 Reddy PS, Dery S, Metanis N. Chemical Synthesis of Proteins with Non-Strategically Placed Cysteines Using Selenazolidine and Selective Deselenization. Angewandte Chemie (International Ed. in English). PMID 26636774 DOI: 10.1002/Anie.201509378  0.598
2015 Metanis N, Hilvert D. Harnessing selenocysteine reactivity for oxidative protein folding Chemical Science. 6: 322-325. DOI: 10.1039/c4sc02379j  0.37
2014 Metanis N, Hilvert D. Natural and synthetic selenoproteins. Current Opinion in Chemical Biology. 22: 27-34. PMID 25261915 DOI: 10.1016/J.Cbpa.2014.09.010  0.668
2013 Metanis N. Chemical protein synthesis (CPS) meeting 2013. Chembiochem : a European Journal of Chemical Biology. 14: 1381-4. PMID 23775940 DOI: 10.1002/Cbic.201300337  0.469
2012 Metanis N, Hilvert D. Strategic use of non-native diselenide bridges to steer oxidative protein folding. Angewandte Chemie (International Ed. in English). 51: 5585-8. PMID 22454335 DOI: 10.1002/Anie.201109129  0.617
2012 Blum C, Schmid T, Opilik L, Metanis N, Weidmann S, Zenobi R. Missing amide i mode in gap-mode tip-enhanced raman spectra of proteins Journal of Physical Chemistry C. 116: 23061-23066. DOI: 10.1021/Jp306831P  0.363
2011 Metanis N, Foletti C, Beld J, Hilvert D. Selenoglutathione-mediated rescue of kinetically trapped intermediates in oxidative protein folding Israel Journal of Chemistry. 51: 953-959. DOI: 10.1002/Ijch.201100105  0.735
2011 Metanis N, Beld J, Hilvert D. The Chemistry of Selenocysteine Patai's Chemistry of Functional Groups. DOI: 10.1002/9780470682531.Pat0582  0.748
2010 Metanis N, Keinan E, Dawson PE. Traceless ligation of cysteine peptides using selective deselenization. Angewandte Chemie (International Ed. in English). 49: 7049-53. PMID 20715234 DOI: 10.1002/Anie.201001900  0.691
2010 Shekhter T, Metanis N, Dawson PE, Keinan E. A residue outside the active site CXXC motif regulates the catalytic efficiency of Glutaredoxin 3. Molecular Biosystems. 6: 241-8. PMID 20024086 DOI: 10.1039/B912753D  0.591
2006 Metanis N, Keinan E, Dawson PE. Synthetic seleno-glutaredoxin 3 analogues are highly reducing oxidoreductases with enhanced catalytic efficiency. Journal of the American Chemical Society. 128: 16684-91. PMID 17177418 DOI: 10.1021/Ja0661414  0.608
2005 Metanis N, Keinan E, Dawson PE. A designed synthetic analogue of 4-OT is specific for a non-natural substrate. Journal of the American Chemical Society. 127: 5862-8. PMID 15839684 DOI: 10.1021/Ja050110B  0.567
2004 Metanis N, Brik A, Dawson PE, Keinan E. Electrostatic interactions dominate the catalytic contribution of arg39 in 4-oxalocrotonate tautomerase. Journal of the American Chemical Society. 126: 12726-7. PMID 15469238 DOI: 10.1021/Ja0463841  0.526
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