Jesper Wengel - Publications

Affiliations: 
1991-1996 Odense University 
 1996-2000 University of Copenhagen, København, Denmark 
 2000- University of Southern Denmark, Odense, Denmark 
Area:
Bioorganic chemistry; nucleic acid biotechnology; Nanobioscience

208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Umek T, Olsson T, Gissberg O, Saher O, Zaghloul EM, Lundin KE, Wengel J, Hanse E, Zetterberg H, Vizlin-Hodzic D, Smith CIE, Zain R. Oligonucleotides Targeting DNA Repeats Downregulate Gene Expression in Huntington's Patient-Derived Neural Model System. Nucleic Acid Therapeutics. PMID 34520257 DOI: 10.1089/nat.2021.0021  1
2021 Laanesoo A, Urgard E, Periyasamy K, Laan M, Bochkov YA, Aab A, Magilnick N, Pooga M, Gern JE, Johnston SL, Coquet JM, Boldin MP, Wengel J, Altraja A, Bochenek G, et al. Dual role of the miR-146 family in rhinovirus-induced airway inflammation and allergic asthma exacerbation. Clinical and Translational Medicine. 11: e427. PMID 34185416 DOI: 10.1002/ctm2.427  1
2021 Laanesoo A, Urgard E, Periyasamy K, Laan M, Bochkov YA, Aab A, Magilnick N, Pooga M, Gern JE, Johnston SL, Coquet JM, Boldin MP, Wengel J, Altraja A, Bochenek G, et al. Dual role of the miR-146 family in rhinovirus-induced airway inflammation and allergic asthma exacerbation. Clinical and Translational Medicine. 11: e427. PMID 34185416 DOI: 10.1002/ctm2.427  1
2021 Pereira S, Yao R, Gomes M, Jørgensen PT, Wengel J, Azevedo NF, Sobral Santos R. Can Vitamin B12 Assist the Internalization of Antisense LNA Oligonucleotides into Bacteria? Antibiotics (Basel, Switzerland). 10. PMID 33916701 DOI: 10.3390/antibiotics10040379  1
2021 Pereira S, Yao R, Gomes M, Jørgensen PT, Wengel J, Azevedo NF, Sobral Santos R. Can Vitamin B12 Assist the Internalization of Antisense LNA Oligonucleotides into Bacteria? Antibiotics (Basel, Switzerland). 10. PMID 33916701 DOI: 10.3390/antibiotics10040379  1
2020 Danielsen MB, Christensen NJ, Jørgensen PT, Jensen KJ, Wengel J, Lou C. Polyamine-functionalized 2'-amino-LNA in oligonucleotides: Facile synthesis of novel monomers and high affinity binding towards ssDNA and dsDNA. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33073896 DOI: 10.1002/chem.202004495  1
2020 Danielsen MB, Christensen NJ, Jørgensen PT, Jensen KJ, Wengel J, Lou C. Polyamine-functionalized 2'-amino-LNA in oligonucleotides: Facile synthesis of novel monomers and high affinity binding towards ssDNA and dsDNA. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33073896 DOI: 10.1002/chem.202004495  1
2020 Gouda AS, Przypis Ł, Walczak K, Jørgensen PT, Wengel J. Carbazole modified oligonucleotides: synthesis, hybridization studies and fluorescence properties. Organic & Biomolecular Chemistry. 18: 6935-6948. PMID 32936176 DOI: 10.1039/d0ob01553a  1
2020 Carreras-Badosa G, Maslovskaja J, Periyasamy K, Urgard E, Padari K, Vaher H, Tserel L, Gestin M, Kisand K, Arukuusk P, Lou C, Langel Ü, Wengel J, Pooga M, Rebane A. NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation. Biomaterials. 262: 120316. PMID 32896817 DOI: 10.1016/j.biomaterials.2020.120316  1
2020 Cai Y, Lou C, Wengel J, Howard KA. Albumin-Binding Fatty Acid-Modified Gapmer Antisense Oligonucleotides for Modulation of Pharmacokinetics. Methods in Molecular Biology (Clifton, N.J.). 2176: 163-174. PMID 32865790 DOI: 10.1007/978-1-0716-0771-8_12  1
2020 Raguraman P, Wang T, Ma L, Jørgensen PT, Wengel J, Veedu RN. Alpha-l-Locked Nucleic Acid-Modified Antisense Oligonucleotides Induce Efficient Splice Modulation In Vitro. International Journal of Molecular Sciences. 21. PMID 32244535 DOI: 10.3390/ijms21072434  1
2020 Raguraman P, Wang T, Ma L, Jørgensen PT, Wengel J, Veedu RN. Alpha-l-Locked Nucleic Acid-Modified Antisense Oligonucleotides Induce Efficient Splice Modulation In Vitro. International Journal of Molecular Sciences. 21. PMID 32244535 DOI: 10.3390/ijms21072434  1
2020 Lou C, Boesen JT, Christensen NJ, Sørensen KK, Thulstrup PW, Pedersen MN, Giralt E, Jensen KJ, Wengel J. Self-assembly of DNA-peptide supermolecules: Coiled-coil peptide structures templated by D-DNA and L-DNA triplexes exhibit chirality-independent but orientation-dependent stabilizing cooperativity. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32022377 DOI: 10.1002/chem.201905636  1
2020 Lou C, Boesen JT, Christensen NJ, Sørensen KK, Thulstrup PW, Pedersen MN, Giralt E, Jensen KJ, Wengel J. Self-assembly of DNA-peptide supermolecules: Coiled-coil peptide structures templated by D-DNA and L-DNA triplexes exhibit chirality-independent but orientation-dependent stabilizing cooperativity. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32022377 DOI: 10.1002/chem.201905636  1
2020 Christou M, Wengel J, Sokratous K, Kyriacou K, Nikolaou G, Phylactou LA, Mastroyiannopoulos NP. Systemic Evaluation of Chimeric LNA/2'-O-Methyl Steric Blockers for Myotonic Dystrophy Type 1 Therapy. Nucleic Acid Therapeutics. 30: 80-93. PMID 31873063 DOI: 10.1089/nat.2019.0811  0.01
2020 Abdelrahman A, Gouda AS, Jørgensen PT, Wengel J. Novel assemblies based on oligonucleotides containing intercalating nucleic acid monomers. Nucleosides, Nucleotides & Nucleic Acids. 39: 82-96. PMID 31674270 DOI: 10.1080/15257770.2019.1683188  1
2020 Matta A, Sharma AK, Tomar S, Cao P, Kumar S, Balwani S, Ghosh B, Prasad AK, Eycken EVVd, DePass AL, Wengel J, Parmar VS, Len C, Singh BK. Synthesis and anti-inflammatory activity evaluation of novel chroman derivatives New Journal of Chemistry. 44: 13716-13727. DOI: 10.1039/D0Nj02125C  1
2020 Zeng D, Salvatore P, Karlsen KK, Zhang J, Wengel J, Ulstrup J. Reprint of "Electrochemical intercalator binding to single- and double-strand DNA- and LNA-based molecules on Au(111)-electrode surfaces" Journal of Electroanalytical Chemistry. 865: 114527. DOI: 10.1016/J.Jelechem.2020.114527  1
2019 Duschmalé J, Hansen HF, Duschmalé M, Koller E, Albaek N, Møller MR, Jensen K, Koch T, Wengel J, Bleicher K. In vitro and in vivo properties of therapeutic oligonucleotides containing non-chiral 3' and 5' thiophosphate linkages. Nucleic Acids Research. PMID 31754711 DOI: 10.1093/nar/gkz1099  1
2019 Danielsen MB, Lou C, Lisowiec-Wachnicka J, Pasternak A, Jørgensen PT, Wengel J. Gapmer antisense oligonucleotides containing 2',3'-dideoxy-2'-fluoro-3'-C-hydroxymethyl-β-D-lyxofuranosyl nucleotides display site-specific RNase H cleavage and induce gene silencing. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31682037 DOI: 10.1002/chem.201904540  1
2019 Yadav Y, Sharma D, Kaushik K, Kumar V, Jha A, Prasad AK, Len C, Malhotra SV, Wengel J, Parmar VS. Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides. Molecules (Basel, Switzerland). 24. PMID 31671703 DOI: 10.3390/molecules24213922  1
2019 Andersen VL, Vinther M, Kumar R, Ries A, Wengel J, Nielsen JS, Kjems J. A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine. Theranostics. 9: 2662-2677. PMID 31131060 DOI: 10.7150/Thno.32060  1
2019 Gasparri F, Wengel J, Grutter T, Pless SA. Molecular determinants for agonist recognition and discrimination in P2X2 receptors. The Journal of General Physiology. PMID 31126967 DOI: 10.1085/Jgp.201912347  0.01
2019 Moura J, Sørensen A, Leal EC, Svendsen R, Carvalho L, Willemoes RJ, Jørgensen PT, Jenssen H, Wengel J, Dalgaard LT, Carvalho E. microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation. Scientific Reports. 9: 5836. PMID 30967591 DOI: 10.1038/s41598-019-42309-4  1
2019 Umek T, Sollander K, Bergquist H, Wengel J, Lundin KE, Smith CIE, Zain R. Oligonucleotide Binding to Non-B-DNA in . Molecules (Basel, Switzerland). 24. PMID 30871121 DOI: 10.3390/Molecules24051000  1
2019 Xu Y, Gissberg O, Pabon-Martinez YV, Wengel J, Lundin KE, Smith CIE, Zain R, Nilsson L, Villa A. The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study. Plos One. 14: e0211651. PMID 30753192 DOI: 10.1371/Journal.Pone.0211651  1
2019 Kotkowiak W, Wengel J, Scotton CJ, Pasternak A. Improved RE31 Analogues Containing Modified Nucleic Acid Monomers: Thermodynamic, Structural, and Biological Effects. Journal of Medicinal Chemistry. 62: 2499-2507. PMID 30735377 DOI: 10.1021/acs.jmedchem.8b01806  1
2018 Garcia JP, Stein J, Cai Y, Riemers F, Wexselblatt E, Wengel J, Tryfonidou M, Yayon A, Howard KA, Creemers LB. Fibrin-hyaluronic acid hydrogel-based delivery of antisense oligonucleotides for ADAMTS5 inhibition in co-delivered and resident joint cells in osteoarthritis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 294: 247-258. PMID 30572032 DOI: 10.1016/j.jconrel.2018.12.030  1
2018 Ferino A, Miglietta G, Picco R, Vogel S, Wengel J, Xodo LE. MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells. Rna Biology. 15: 1273-1285. PMID 30306823 DOI: 10.1080/15476286.2018.1526536  0.01
2018 Ejlersen M, Lou C, Sanghvi YS, Tor Y, Wengel J. Modification of oligodeoxynucleotides by on-column Suzuki cross-coupling reactions. Chemical Communications (Cambridge, England). PMID 29967912 DOI: 10.1039/C8Cc01360H  1
2018 Lima JF, Carvalho J, Pinto-Ribeiro I, Almeida C, Wengel J, Cerqueira L, Figueiredo C, Oliveira C, Azevedo NF. Targeting miR-9 in gastric cancer cells using locked nucleic acid oligonucleotides. Bmc Molecular Biology. 19: 6. PMID 29879907 DOI: 10.1186/s12867-018-0107-6  1
2018 Moreno PMD, Ferreira AR, Salvador D, Rodrigues MT, Torrado M, Carvalho ED, Tedebark U, Sousa MM, Amaral IF, Wengel J, Pêgo AP. Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury. Molecular Therapy. Nucleic Acids. 11: 393-406. PMID 29858074 DOI: 10.1016/j.omtn.2018.03.009  0.01
2018 Cai Y, Makarova AM, Wengel J, Howard KA. Palmitoylated phosphodiester gapmer designs with albumin binding capacity and maintained in vitro gene silencing activity. The Journal of Gene Medicine. e3025. PMID 29800498 DOI: 10.1002/jgm.3025  1
2018 Ejlersen M, Christensen NJ, Sørensen KK, Jensen KJ, Wengel J, Lou C. Synergy of two highly specific biomolecular recognition events: aligning an AT-hook peptide in DNA minor grooves via covalent conjugation to 2'-amino-LNA. Bioconjugate Chemistry. PMID 29505242 DOI: 10.1021/acs.bioconjchem.8b00101  1
2018 Kotkowiak W, Lisowiec-Wachnicka J, Grynda J, Kierzek R, Wengel J, Pasternak A. Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative. Molecular Therapy. Nucleic Acids. 10: 304-316. PMID 29499943 DOI: 10.1016/j.omtn.2017.12.013  1
2018 Vejlegaard K, Wegeberg C, McKee V, Wengel J. Novel conformationally constrained 2'-C-methylribonucleosides: synthesis and incorporation into oligonucleotides. Organic & Biomolecular Chemistry. PMID 29392247 DOI: 10.1039/c7ob02663c  1
2017 Hartono YD, Pabon-Martinez YV, Uyar A, Wengel J, Lundin KE, Zain R, Smith CIE, Nilsson L, Villa A. Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies. Acs Omega. 2: 2165-2177. PMID 30023656 DOI: 10.1021/acsomega.7b00347  1
2017 Kuhlmann M, Hamming JBR, Voldum A, Tsakiridou G, Larsen MT, Schmøkel JS, Sohn E, Bienk K, Schaffert D, Sørensen ES, Wengel J, Dupont DM, Howard KA. An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications. Molecular Therapy. Nucleic Acids. 9: 284-293. PMID 29246307 DOI: 10.1016/j.omtn.2017.10.004  1
2017 Pabon-Martinez YV, Xu Y, Villa A, Lundin KE, Geny S, Nguyen CH, Pedersen EB, Jørgensen PT, Wengel J, Nilsson L, Smith CIE, Zain R. LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures. Scientific Reports. 7: 11043. PMID 28887512 DOI: 10.1038/S41598-017-09147-8  1
2017 Hvam ML, Cai Y, Dagnæs-Hansen F, Nielsen JS, Wengel J, Kjems J, Howard KA. Fatty Acid-Modified Gapmer Antisense Oligonucleotide and Serum Albumin Constructs for Pharmacokinetic Modulation. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28641935 DOI: 10.1016/J.Ymthe.2017.05.009  1
2017 Vejlegaard K, Paul S, Kosbar T, Wengel J, Caruthers MH. Oligodeoxynucleotides containing 2'-amino-LNA nucleotides as constrained morpholino phosphoramidate and phosphorodiamidate monomers. Bioorganic & Medicinal Chemistry Letters. PMID 28552336 DOI: 10.1016/j.bmcl.2017.05.023  1
2017 Kumar R, Ries A, Wengel J. Synthesis and Excellent Duplex Stability of Oligonucleotides Containing 2'-Amino-LNA Functionalized with Galactose Units. Molecules (Basel, Switzerland). 22. PMID 28531137 DOI: 10.3390/molecules22050852  1
2017 Lou C, Christensen NJ, Martos-Maldonado MC, Midtgaard SR, Ejlersen M, Thulstrup PW, Sørensen KK, Jensen KJ, Wengel J. Folding Topology of a Short Coiled Coil Peptide Structure Templated by an Oligonucleotide Triplex. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28383784 DOI: 10.1002/chem.201700971  1
2017 Schmøkel J, Voldum A, Tsakiridou G, Kuhlmann M, Cameron J, Sørensen E, Wengel J, Howard KA. Site-selective conjugation of an anticoagulant aptamer to recombinant albumins and maintenance of neonatal Fc receptor binding. Nanotechnology. PMID 28362634 DOI: 10.1088/1361-6528/aa6a9b  1
2017 Zaghloul EM, Gissberg O, Moreno PM, Siggens L, Hällbrink M, Jørgensen AS, Ekwall K, Zain R, Wengel J, Lundin KE, Smith CI. CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression. Nucleic Acids Research. PMID 28334749 DOI: 10.1093/Nar/Gkx111  1
2017 Lou C, Samuelsen SV, Christensen NJ, Vester B, Wengel J. Oligonucleotides Containing Aminated 2'-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA. Bioconjugate Chemistry. PMID 28332825 DOI: 10.1021/acs.bioconjchem.7b00061  1
2017 Cai Y, López-Ruiz E, Wengel J, Creemers LB, Howard KA. A hyaluronic acid-based hydrogel enabling CD44-mediated chondrocyte binding and gapmer oligonucleotide release for modulation of gene expression in osteoarthritis. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28274742 DOI: 10.1016/j.jconrel.2017.03.004  1
2017 Ejlersen M, Langkjær N, Wengel J. 3'-Pyrene-modified unlocked nucleic acids: synthesis, fluorescence properties and a surprising stabilization effect on duplexes and triplexes. Organic & Biomolecular Chemistry. 15: 2073-2085. PMID 28210721 DOI: 10.1039/c6ob02773c  1
2017 Aaldering LJ, Poongavanam V, Langkjaer N, Murugan NA, Jørgensen PT, Wengel J, Veedu RN. Development of an Efficient G-Quadruplex-Stabilised Thrombin-Binding Aptamer Containing a Three-Carbon Spacer Molecule. Chembiochem : a European Journal of Chemical Biology. 18: 755-763. PMID 28150905 DOI: 10.1002/cbic.201600654  1
2016 Ries A, Kumar R, Lou C, Kosbar T, Vengut-Climent E, Jørgensen PT, Morales JC, Wengel J. Synthesis and Biophysical Investigations of Oligonucleotides Containing Galactose-Modified DNA, LNA and 2'-Amino-LNA Monomers. The Journal of Organic Chemistry. PMID 27736097 DOI: 10.1021/acs.joc.6b01917  1
2016 Lou C, Martos-Maldonado MC, Madsen CS, Thomsen RP, Midtgaard SR, Christensen NJ, Kjems J, Thulstrup PW, Wengel J, Jensen KJ. Peptide-oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic. Nature Communications. 7: 12294. PMID 27464951 DOI: 10.1038/Ncomms12294  1
2016 Bienk K, Hvam ML, Pakula MM, Dagnæs-Hansen F, Wengel J, Malle BM, Kragh-Hansen U, Cameron J, Bukrinski JT, Howard KA. An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27084489 DOI: 10.1016/j.jconrel.2016.04.013  1
2016 Fontenete S, Carvalho D, Guimarães N, Madureira P, Figueiredo C, Wengel J, Azevedo NF. Application of locked nucleic acid-based probes in fluorescence in situ hybridization. Applied Microbiology and Biotechnology. 100: 5897-906. PMID 26969040 DOI: 10.1007/s00253-016-7429-4  1
2016 Gissberg O, Zaghloul EM, Lundin KE, Nguyen CH, Landras-Guetta C, Wengel J, Zain R, Smith CI. Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs. Nucleic Acid Therapeutics. PMID 26859550 DOI: 10.1089/Nat.2015.0592  1
2016 Geny S, Moreno PM, Krzywkowski T, Gissberg O, Andersen NK, Isse AJ, El-Madani AM, Lou C, Pabon YV, Anderson BA, Zaghloul EM, Zain R, Hrdlicka PJ, Jørgensen PT, Nilsson M, ... ... Wengel J, et al. Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes. Nucleic Acids Research. PMID 26857548 DOI: 10.1093/Nar/Gkw021  1
2016 Fontenete S, Leite M, Cappoen D, Santos R, Ginneken CV, Figueiredo C, Wengel J, Cos P, Azevedo NF. Fluorescence In Vivo Hybridization (FIVH) for Detection of Helicobacter pylori Infection in a C57BL/6 Mouse Model. Plos One. 11: e0148353. PMID 26848853 DOI: 10.1371/journal.pone.0148353  1
2016 Fontenete S, Guimarães N, Wengel J, Azevedo NF. Prediction of melting temperatures in fluorescence in situ hybridization (FISH) procedures using thermodynamic models. Critical Reviews in Biotechnology. 36: 566-77. PMID 25586037 DOI: 10.3109/07388551.2014.993589  1
2015 Santos RS, Dakwar GR, Xiong R, Forier K, Remaut K, Stremersch S, Guimarães N, Fontenete S, Wengel J, Leite M, Figueiredo C, De Smedt SC, Braeckmans K, Azevedo NF. Effect of Native Gastric Mucus on in vivo Hybridization Therapies Directed at Helicobacter pylori. Molecular Therapy. Nucleic Acids. 4: e269. PMID 26645765 DOI: 10.1038/mtna.2015.46  1
2015 Langkjær N, Wengel J, Pasternak A. Watson-Crick hydrogen bonding of unlocked nucleic acids. Bioorganic & Medicinal Chemistry Letters. 25: 5064-6. PMID 26497284 DOI: 10.1016/j.bmcl.2015.10.024  1
2015 Opazo F, Eiden L, Hansen L, Rohrbach F, Wengel J, Kjems J, Mayer G. Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer. Molecular Therapy. Nucleic Acids. 4: e251. PMID 26325628 DOI: 10.1038/Mtna.2015.25  1
2015 Edwards SL, Poongavanam V, Kanwar JR, Roy K, Hillman KM, Prasad N, Leth-Larsen R, Petersen M, Maruši? M, Plavec J, Wengel J, Veedu RN. Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition. Chemical Communications (Cambridge, England). 51: 9499-502. PMID 25968110 DOI: 10.1039/c5cc02756j  1
2015 Fontenete S, Leite M, Guimarães N, Madureira P, Ferreira RM, Figueiredo C, Wengel J, Azevedo NF. Towards Fluorescence In Vivo Hybridization (FIVH) Detection of H. pylori in Gastric Mucosa Using Advanced LNA Probes. Plos One. 10: e0125494. PMID 25915865 DOI: 10.1371/journal.pone.0125494  1
2015 Fontenete S, Barros J, Madureira P, Figueiredo C, Wengel J, Azevedo NF. Erratum to: mismatch discrimination in fluorescent in situ hybridization using different types of nucleic acids. Applied Microbiology and Biotechnology. 99: 4117. PMID 25846338 DOI: 10.1007/s00253-015-6568-3  1
2015 Fontenete S, Silvia F, Barros J, Joana B, Madureira P, Pedro M, Figueiredo C, Céu F, Wengel J, Jesper W, Azevedo NF, Filipe AN. Mismatch discrimination in fluorescent in situ hybridization using different types of nucleic acids. Applied Microbiology and Biotechnology. 99: 3961-9. PMID 25840566 DOI: 10.1007/s00253-015-6389-4  1
2015 Elle IC, Karlsen KK, Terp MG, Larsen N, Nielsen R, Derbyshire N, Mandrup S, Ditzel HJ, Wengel J. Selection of LNA-containing DNA aptamers against recombinant human CD73. Molecular Biosystems. 11: 1260-70. PMID 25720604 DOI: 10.1039/c5mb00045a  1
2015 Lou C, Vester B, Wengel J. Oligonucleotides containing a piperazino-modified 2'-amino-LNA monomer exhibit very high duplex stability and remarkable nuclease resistance. Chemical Communications (Cambridge, England). 51: 4024-7. PMID 25659978 DOI: 10.1039/c5cc00322a  1
2015 Elle IC, Karlsen KK, Terp MG, Larsen N, Nielsen R, Derbyshire N, Mandrup S, Ditzel HJ, Wengel J. Selection of LNA-containing DNA aptamers against recombinant human CD73 Molecular Biosystems. 11: 1260-1270. DOI: 10.1039/c5mb00045a  1
2015 Lou C, Vester B, Wengel J. Oligonucleotides containing a piperazino-modified 2′-amino-LNA monomer exhibit very high duplex stability and remarkable nuclease resistance Chemical Communications. 51: 4024-4027. DOI: 10.1039/c5cc00322a  1
2014 Tolle F, Wilke J, Wengel J, Mayer G. By-product formation in repetitive PCR amplification of DNA libraries during SELEX. Plos One. 9: e114693. PMID 25490402 DOI: 10.1371/Journal.Pone.0114693  1
2014 Hövelmann F, Gaspar I, Loibl S, Ermilov EA, Röder B, Wengel J, Ephrussi A, Seitz O. Brightness through local constraint--LNA-enhanced FIT hybridization probes for in vivo ribonucleotide particle tracking. Angewandte Chemie (International Ed. in English). 53: 11370-5. PMID 25167966 DOI: 10.1002/Anie.201406022  1
2014 Bestas B, Moreno PM, Blomberg KE, Mohammad DK, Saleh AF, Sutlu T, Nordin JZ, Guterstam P, Gustafsson MO, Kharazi S, Pi?tosa B, Roberts TC, Behlke MA, Wood MJ, Gait MJ, ... ... Wengel J, et al. Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model. The Journal of Clinical Investigation. 124: 4067-81. PMID 25105368 DOI: 10.1172/JCI76175  1
2014 Perlíková P, Ejlersen M, Langkjaer N, Wengel J. Bis-pyrene-modified unlocked nucleic acids: synthesis, hybridization studies, and fluorescent properties. Chemmedchem. 9: 2120-7. PMID 25044312 DOI: 10.1002/cmdc.201402185  1
2014 Astakhova IK, Wengel J. Scaffolding along nucleic acid duplexes using 2'-amino-locked nucleic acids. Accounts of Chemical Research. 47: 1768-77. PMID 24749544 DOI: 10.1021/ar500014g  1
2014 Jørgensen AS, Hansen LH, Vester B, Wengel J. Improvement of a streptavidin-binding aptamer by LNA- and α-l-LNA-substitutions. Bioorganic & Medicinal Chemistry Letters. 24: 2273-7. PMID 24745966 DOI: 10.1016/j.bmcl.2014.03.082  1
2014 Xu L, Butler KV, Chong J, Wengel J, Kool ET, Wang D. Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues. Nucleic Acids Research. 42: 5863-70. PMID 24692664 DOI: 10.1093/Nar/Gku238  1
2014 Perlíková P, Karlsen KK, Pedersen EB, Wengel J. Unlocked nucleic acids with a pyrene-modified uracil: synthesis, hybridization studies, fluorescent properties and i-motif stability. Chembiochem : a European Journal of Chemical Biology. 15: 146-56. PMID 24501777 DOI: 10.1002/cbic.201300567  1
2014 Pofahl M, Wengel J, Mayer G. Multifunctional nucleic acids for tumor cell treatment. Nucleic Acid Therapeutics. 24: 171-7. PMID 24494617 DOI: 10.1089/Nat.2013.0472  1
2013 Andersen NK, Anderson BA, Wengel J, Hrdlicka PJ. Synthesis and characterization of oligodeoxyribonucleotides modified with 2'-amino-α-L-LNA adenine monomers: high-affinity targeting of single-stranded DNA. The Journal of Organic Chemistry. 78: 12690-702. PMID 24304240 DOI: 10.1021/Jo4022937  1
2013 Fontenete S, Guimarães N, Leite M, Figueiredo C, Wengel J, Filipe Azevedo N. Hybridization-based detection of Helicobacter pylori at human body temperature using advanced locked nucleic acid (LNA) probes. Plos One. 8: e81230. PMID 24278398 DOI: 10.1371/journal.pone.0081230  1
2013 Xu L, Plouffe SW, Chong J, Wengel J, Wang D. A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids Angewandte Chemie. 52: 12341-12345. PMID 24167045 DOI: 10.1002/Anie.201307661  1
2013 Jørgensen AS, Gupta P, Wengel J, Astakhova IK. "Clickable" LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies. Chemical Communications (Cambridge, England). 49: 10751-3. PMID 24107917 DOI: 10.1039/c3cc45507f  1
2013 Sau SP, Madsen AS, Podbevsek P, Andersen NK, Kumar TS, Andersen S, Rathje RL, Anderson BA, Guenther DC, Karmakar S, Kumar P, Plavec J, Wengel J, Hrdlicka PJ. Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA. The Journal of Organic Chemistry. 78: 9560-70. PMID 24032477 DOI: 10.1021/Jo4015936  1
2013 Marušič M, Veedu RN, Wengel J, Plavec J. G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold. Nucleic Acids Research. 41: 9524-36. PMID 23935071 DOI: 10.1093/nar/gkt697  1
2013 Salvatore P, Zeng D, Karlsen KK, Chi Q, Wengel J, Ulstrup J. Electrochemistry of single metalloprotein and DNA-based molecules at Au(111) electrode surfaces. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 14: 2101-11. PMID 23788363 DOI: 10.1002/Cphc.201300299  1
2013 Lundin KE, Højland T, Hansen BR, Persson R, Bramsen JB, Kjems J, Koch T, Wengel J, Smith CI. Biological activity and biotechnological aspects of locked nucleic acids. Advances in Genetics. 82: 47-107. PMID 23721720 DOI: 10.1016/B978-0-12-407676-1.00002-0  1
2013 Karlsen KK, Okholm A, Kjems J, Wengel J. A quencher-free molecular beacon design based on pyrene excimer fluorescence using pyrene-labeled UNA (unlocked nucleic acid). Bioorganic & Medicinal Chemistry. 21: 6186-90. PMID 23693070 DOI: 10.1016/J.Bmc.2013.04.062  1
2013 Astakhova IK, Hansen LH, Vester B, Wengel J. Peptide-LNA oligonucleotide conjugates. Organic & Biomolecular Chemistry. 11: 4240-9. PMID 23681061 DOI: 10.1039/c3ob40786a  1
2013 Astakhova IK, Pasternak K, Campbell MA, Gupta P, Wengel J. A locked nucleic acid-based nanocrawler: designed and reversible movement detected by multicolor fluorescence. Journal of the American Chemical Society. 135: 2423-6. PMID 23379691 DOI: 10.1021/Ja311250W  1
2013 Moreno PM, Geny S, Pabon YV, Bergquist H, Zaghloul EM, Rocha CS, Oprea II, Bestas B, Andaloussi SE, Jørgensen PT, Pedersen EB, Lundin KE, Zain R, Wengel J, Smith CI. Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA. Nucleic Acids Research. 41: 3257-73. PMID 23345620 DOI: 10.1093/Nar/Gkt007  1
2013 Astakhova IK, Kumar TS, Campbell MA, Ustinov AV, Korshun VA, Wengel J. Branched DNA nanostructures efficiently stabilised and monitored by novel pyrene-perylene 2'-α-L-amino-LNA FRET pairs. Chemical Communications (Cambridge, England). 49: 511-3. PMID 23201901 DOI: 10.1039/C2Cc37547H  1
2013 Astakhova IK, Wengel J. Interfacing click chemistry with automated oligonucleotide synthesis for the preparation of fluorescent DNA probes containing internal xanthene and cyanine dyes. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 1112-22. PMID 23180379 DOI: 10.1002/chem.201202621  1
2013 Hansen AG, Salvatore P, Karlsen KK, Nichols RJ, Wengel J, Ulstrup J. Electrochemistry and in situ scanning tunnelling microscopy of pure and redox-marked DNA- and UNA-based oligonucleotides on Au(111)-electrode surfaces. Physical Chemistry Chemical Physics : Pccp. 15: 776-86. PMID 23073185 DOI: 10.1039/C2Cp42351K  1
2013 Attwater J, Tagami S, Kimoto M, Butler K, Kool ET, Wengel J, Herdewijn P, Hirao I, Holliger P. Chemical fidelity of an RNA polymerase ribozyme Chemical Science. 4: 2804-2814. DOI: 10.1039/C3Sc50574J  1
2013 Barbeyron R, Wengel J, Vasseur JJ, Smietana M. Boronic acid-based autoligation of nucleic acids: Influence of the nature of the 3′-end ribonucleotidic strand Monatshefte Fur Chemie. 144: 495-500. DOI: 10.1007/S00706-012-0881-7  1
2013 Xu L, Plouffe SW, Chong J, Wengel J, Wang D. Inside Cover: A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids (Angew. Chem. Int. Ed. 47/2013) Angewandte Chemie. 52: 12196-12196. DOI: 10.1002/Anie.201309065  1
2013 Xu L, Plouffe SW, Chong J, Wengel J, Wang D. Innentitelbild: A Chemical Perspective on Transcriptional Fidelity: Dominant Contributions of Sugar Integrity Revealed by Unlocked Nucleic Acids (Angew. Chem. 47/2013) Angewandte Chemie. 125: 12418-12418. DOI: 10.1002/Ange.201309065  1
2012 Singh SK, Reddy LC, Srivastava S, Olsen CE, Sanghvi YS, Langkjær N, Wengel J, Parmar VS, Prasad AK. Selective biocatalytic acylation studies on 5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine: an efficient synthesis of UNA monomer. Nucleosides, Nucleotides & Nucleic Acids. 31: 831-40. PMID 23215547 DOI: 10.1080/15257770.2012.734424  1
2012 Karlsen KK, Wengel J. Locked nucleic acid and aptamers. Nucleic Acid Therapeutics. 22: 366-70. PMID 23181700 DOI: 10.1089/nat.2012.0382  1
2012 Madsen AS, Jørgensen AS, Jensen TB, Wengel J. Large scale synthesis of 2'-amino-LNA thymine and 5-methylcytosine nucleosides. The Journal of Organic Chemistry. 77: 10718-28. PMID 23145501 DOI: 10.1021/jo302036h  1
2012 Doessing H, Hansen LH, Veedu RN, Wengel J, Vester B. Amplification and re-generation of LNA-modified libraries. Molecules (Basel, Switzerland). 17: 13087-97. PMID 23128088 DOI: 10.3390/molecules171113087  1
2012 Wenge U, Wengel J, Wagenknecht HA. Photoinduced reductive electron transfer in LNA:DNA hybrids: a compromise between conformation and base stacking. Angewandte Chemie (International Ed. in English). 51: 10026-9. PMID 22945791 DOI: 10.1002/Anie.201204901  0.01
2012 Astakhova IK, Samokhina E, Babu BR, Wengel J. Novel (phenylethynyl)pyrene-LNA constructs for fluorescence SNP sensing in polymorphic nucleic acid targets. Chembiochem : a European Journal of Chemical Biology. 13: 1509-19. PMID 22761036 DOI: 10.1002/cbic.201200079  1
2012 Crouzier L, Dubois C, Wengel J, Veedu RN. Cleavage and protection of locked nucleic acid-modified DNA by restriction endonucleases. Bioorganic & Medicinal Chemistry Letters. 22: 4836-8. PMID 22727669 DOI: 10.1016/j.bmcl.2012.05.113  1
2012 Højland T, Veedu RN, Vester B, Wengel J. Enzymatic synthesis of DNA strands containing α-L-LNA (α-L-configured locked nucleic acid) thymine nucleotides. Artificial Dna, Pna & Xna. 3: 14-21. PMID 22679529 DOI: 10.4161/adna.19272  1
2012 Crouzier L, Dubois C, Edwards SL, Lauridsen LH, Wengel J, Veedu RN. Efficient reverse transcription using locked nucleic acid nucleotides towards the evolution of nuclease resistant RNA aptamers Plos One. 7: e35990. PMID 22558297  1
2012 Dubois C, Campbell MA, Edwards SL, Wengel J, Veedu RN. Stepping towards highly flexible aptamers: Enzymatic recognition studies of unlocked nucleic acid nucleotides Chemical Communications. 48: 5503-5505. PMID 22540128 DOI: 10.1039/C2Cc31316B  1
2012 Pinheiro VB, Taylor AI, Cozens C, Abramov M, Renders M, Zhang S, Chaput JC, Wengel J, Peak-Chew SY, McLaughlin SH, Herdewijn P, Holliger P. Synthetic genetic polymers capable of heredity and evolution. Science (New York, N.Y.). 336: 341-4. PMID 22517858 DOI: 10.1126/Science.1217622  1
2012 Johannsen MW, Veedu RN, Madsen AS, Wengel J. Enzymatic polymerisation involving 2'-amino-LNA nucleotides. Bioorganic & Medicinal Chemistry Letters. 22: 3522-6. PMID 22503454 DOI: 10.1016/j.bmcl.2012.03.073  1
2012 Muñoz-Alarcón A, Guterstam P, Romero C, Behlke MA, Lennox KA, Wengel J, El Andaloussi S, Langel U. Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization. Isrn Pharmaceutics. 2012: 407154. PMID 22474606 DOI: 10.5402/2012/407154  1
2012 Madsen AS, Wengel J. Oligonucleotides with 1,4-dioxane-based nucleotide monomers. The Journal of Organic Chemistry. 77: 3878-86. PMID 22439826 DOI: 10.1021/jo300222q  1
2012 Karlsen KK, Pasternak A, Jensen TB, Wengel J. Pyrene-modified unlocked nucleic acids: synthesis, thermodynamic studies, and fluorescent properties. Chembiochem : a European Journal of Chemical Biology. 13: 590-601. PMID 22315188 DOI: 10.1002/cbic.201100689  1
2012 Schyth BD, Bramsen JB, Pakula MM, Larashati S, Kjems J, Wengel J, Lorenzen N. In vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are important. Nucleic Acids Research. 40: 4653-65. PMID 22287630 DOI: 10.1093/Nar/Gks033  1
2011 Pasternak K, Pasternak A, Gupta P, Veedu RN, Wengel J. Photoligation of self-assembled DNA constructs containing anthracene-functionalized 2'-amino-LNA monomers. Bioorganic & Medicinal Chemistry. 19: 7407-15. PMID 22079866 DOI: 10.1016/j.bmc.2011.10.052  1
2011 Pasternak K, Pasternak A, Gupta P, Veedu RN, Wengel J. Photoligation of self-assembled DNA constructs containing anthracene-functionalized 2'-amino-LNA monomers. Bioorganic & Medicinal Chemistry. 19: 7407-15. PMID 22079866 DOI: 10.1016/j.bmc.2011.10.052  1
2011 Jensen TB, Henriksen JR, Rasmussen BE, Rasmussen LM, Andresen TL, Wengel J, Pasternak A. Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2′-C-piperazino-UNA monomer Bioorganic and Medicinal Chemistry. 19: 4739-4745. PMID 21795054 DOI: 10.1016/j.bmc.2011.06.087  1
2011 Campbell MA, Wengel J. Locked vs. unlocked nucleic acids (LNA vs. UNA): contrasting structures work towards common therapeutic goals. Chemical Society Reviews. 40: 5680-9. PMID 21556437 DOI: 10.1039/C1Cs15048K  1
2011 Johannsen MW, Crispino L, Wamberg MC, Kalra N, Wengel J. Amino acids attached to 2′-amino-LNA: Synthesis and excellent duplex stability Organic and Biomolecular Chemistry. 9: 243-252. PMID 21049102 DOI: 10.1039/c0ob00532k  1
2011 Pasternak A, Hernandez FJ, Rasmussen LM, Vester B, Wengel J. Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer. Nucleic Acids Research. 39: 1155-64. PMID 20870750 DOI: 10.1093/nar/gkq823  1
2011 Campbell MA, Wengel J. Exploring unique properties of unlocked nucleic acid Collection of Czechoslovak Chemical Communications. 12: 18-26. DOI: 10.1135/Css201112018  1
2010 Østergaard ME, Maity J, Babu BR, Wengel J, Hrdlicka PJ. Novel insights into the use of Glowing LNA as nucleic acid detection probes--influence of labeling density and nucleobases. Bioorganic & Medicinal Chemistry Letters. 20: 7265-8. PMID 21071224 DOI: 10.1016/J.Bmcl.2010.10.089  1
2010 Singh SK, Sharma VK, Olsen CE, Wengel J, Parmar VS, Prasad AK. Biocatalytic separation of N-7/N-9 guanine nucleosides. The Journal of Organic Chemistry. 75: 7932-5. PMID 20973519 DOI: 10.1021/jo101565e  1
2010 Veedu RN, Burri HV, Kumar P, Sharma PK, Hrdlicka PJ, Vester B, Wengel J. Polymerase-directed synthesis of C5-ethynyl locked nucleic acids. Bioorganic & Medicinal Chemistry Letters. 20: 6565-8. PMID 20932755 DOI: 10.1016/J.Bmcl.2010.09.044  1
2010 Madsen AS, Kumar TS, Wengel J. LNA 5'-phosphoramidites for 5'→3'-oligonucleotide synthesis. Organic & Biomolecular Chemistry. 8: 5012-6. PMID 20820663 DOI: 10.1039/c0ob00346h  1
2010 Laursen MB, Pakula MM, Gao S, Fluiter K, Mook OR, Baas F, Langklaer N, Wengel SL, Wengel J, Kjems J, Bramsen JB. Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo. Molecular Biosystems. 6: 862-70. PMID 20567772 DOI: 10.1039/B918869J  1
2010 Bramsen JB, Pakula MM, Hansen TB, Bus C, Langkjær N, Odadzic D, Smicius R, Wengel SL, Chattopadhyaya J, Engels JW, Herdewijn P, Wengel J, Kjems J. A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects. Nucleic Acids Research. 38: 5761-73. PMID 20453030 DOI: 10.1093/Nar/Gkq341  1
2010 Mollenhauer J, Stamou D, Flyvbjerg A, Wengel J, Gether U, Kjems J, Bjørnholm T, Besenbacher F. David versus Goliath. Nanomedicine : Nanotechnology, Biology, and Medicine. 6: 504-9. PMID 20417315 DOI: 10.1016/J.Nano.2010.04.002  1
2010 Gondela A, Kumar TS, Walczak K, Wengel J. Synthesis and biophysical properties of oligodeoxynucleotides containing 2'-deoxy-5-(4-nitro-1H-imidazol-1-yl)-beta-D-uridine and 2'-deoxy-5-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-beta-D-uridine monomers. Chemistry & Biodiversity. 7: 350-62. PMID 20151382 DOI: 10.1002/cbdv.200900195  1
2009 Hernandez FJ, Kalra N, Wengel J, Vester B. Aptamers as a model for functional evaluation of LNA and 2'-amino LNA. Bioorganic & Medicinal Chemistry Letters. 19: 6585-7. PMID 19864131 DOI: 10.1016/j.bmcl.2009.10.039  1
2009 Gupta P, Maity J, Shakya G, Prasad AK, Parmar VS, Wengel J. Synthesis and hybridization studies of alpha-configured arabino nucleic acids. Organic & Biomolecular Chemistry. 7: 2389-401. PMID 19462050 DOI: 10.1039/b905019c  1
2009 Glud SZ, Bramsen JB, Dagnaes-Hansen F, Wengel J, Howard KA, Nyengaard JR, Kjems J. Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration. Oligonucleotides. 19: 163-8. PMID 19441893 DOI: 10.1089/Oli.2008.0175  1
2009 Gao S, Dagnaes-Hansen F, Nielsen EJ, Wengel J, Besenbacher F, Howard KA, Kjems J. The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1225-33. PMID 19401674 DOI: 10.1038/Mt.2009.91  1
2009 Kumar TS, Ostergaard ME, Sharma PK, Nielsen P, Wengel J, Hrdlicka PJ. Parallel RNA-strand recognition by 2'-amino-beta-L-LNA. Bioorganic & Medicinal Chemistry Letters. 19: 2396-9. PMID 19356930 DOI: 10.1016/J.Bmcl.2009.03.079  1
2009 Bramsen JB, Laursen MB, Nielsen AF, Hansen TB, Bus C, Langkjoør N, Babu BR, Højland T, Abramov M, Van Aerschot A, Odadzic D, Smicius R, Haas J, Andree C, Barman J, ... ... Wengel J, et al. A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity Nucleic Acids Research. 37: 2867-2881. PMID 19282453 DOI: 10.1093/Nar/Gkp106  1
2009 Kumar TS, Madsen AS, Østergaard ME, Sau SP, Wengel J, Hrdlicka PJ. Functionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting. The Journal of Organic Chemistry. 74: 1070-81. PMID 19108636 DOI: 10.1021/Jo802037V  1
2008 Singh SK, Sharma RK, Maity J, Wengel J, Parmar VS, Prasad AK. Greener biocatalytic approach to the synthesis of nucleosides and their precursors. Nucleic Acids Symposium Series (2004). 273-4. PMID 18776359 DOI: 10.1093/nass/nrn138  1
2008 Astakhova IV, Korshun VA, Jahn K, Kjems J, Wengel J. Perylene attached to 2'-amino-LNA: synthesis, incorporation into oligonucleotides, and remarkable fluorescence properties in vitro and in cell culture. Bioconjugate Chemistry. 19: 1995-2007. PMID 18771303 DOI: 10.1021/Bc800202V  1
2008 Kumar TS, Madsen AS, Østergaard ME, Wengel J, Hrdlicka PJ. Nucleic acid structural engineering using pyrene-functionalized 2'-amino-alpha-L-LNA monomers and abasic sites. The Journal of Organic Chemistry. 73: 7060-6. PMID 18710289 DOI: 10.1021/Jo800551J  1
2008 Kalek M, Benediktson P, Vester B, Wengel J. Identification of efficient and sequence specific bimolecular artificial ribonucleases by a combinatorial approach. Chemical Communications (Cambridge, England). 762-4. PMID 18478716 DOI: 10.1039/B712532A  1
2008 Kalek M, Benediktson P, Vester B, Wengel J. Identification of efficient and sequence specific bimolecular artificial ribonucleases by a combinatorial approach. Chemical Communications (Cambridge, England). 762-4. PMID 18478716 DOI: 10.1039/B712532A  1
2008 Vester B, Boel AM, Lobedanz S, Babu BR, Raunkjaer M, Lindegaard D, Raunak, Hrdlicka PJ, Højland T, Sharma PK, Kumar S, Nielsen P, Wengel J. Chemically modified oligonucleotides with efficient RNase H response. Bioorganic & Medicinal Chemistry Letters. 18: 2296-300. PMID 18356048 DOI: 10.1016/J.Bmcl.2008.03.004  1
2008 Guterstam P, Lindgren M, Johansson H, Tedebark U, Wengel J, El Andaloussi S, Langel U. Splice-switching efficiency and specificity for oligonucleotides with locked nucleic acid monomers. The Biochemical Journal. 412: 307-13. PMID 18271753 DOI: 10.1042/BJ20080013  1
2008 Desnous C, Babu BR, Moriou C, Mayo JU, Favre A, Wengel J, Clivio P. The sugar conformation governs (6-4) photoproduct formation at the dinucleotide level. Journal of the American Chemical Society. 130: 30-1. PMID 18069836 DOI: 10.1021/ja077095q  1
2007 Prasad AK, Singh SK, Kalra N, Singhal N, Wengel J, Parmar VS. Novel selective biocatalytic deacylation studies on key precursors for bicyclonucleosides. Nucleosides, Nucleotides & Nucleic Acids. 26: 1517-21. PMID 18066818 DOI: 10.1080/15257770701544302  1
2007 Andersen NK, Wengel J, Hrdlicka PJ. N2'-functionalized 2'-amino-alpha-L-LNA adenine derivatives--efficient targeting of single stranded DNA. Nucleosides, Nucleotides & Nucleic Acids. 26: 1415-7. PMID 18066795 DOI: 10.1080/15257770701539153  1
2007 Kumar TS, Wengel J, Hrdlicka PJ. Pyrene-functionalized 2'-amino-alpha-L-LNA as potential diagnostic probes. Nucleosides, Nucleotides & Nucleic Acids. 26: 1407-9. PMID 18066793 DOI: 10.1080/15257770701538908  1
2007 Kumar TS, Madsen AS, Wengel J, Hrdlicka PJ. Synthesis and biophysical studies of N2'-functionalized 2'-amino-alpha-L-LNA. Nucleosides, Nucleotides & Nucleic Acids. 26: 1403-5. PMID 18066792 DOI: 10.1080/15257770701538841  1
2007 Umemoto T, Hrdlicka PJ, Babu BR, Wengel J. Dual-probe system using pyrenylmethyl-modified amino-LNA for mismatch detection. Nucleosides, Nucleotides & Nucleic Acids. 26: 1261-3. PMID 18066764 DOI: 10.1080/15257770701528255  1
2007 Umemoto T, Hrdlicka PJ, Babu BR, Wengel J. Sensitive SNP dual-probe assays based on pyrene-functionalized 2'-amino-LNA: lessons to be learned. Chembiochem : a European Journal of Chemical Biology. 8: 2240-8. PMID 17979173 DOI: 10.1002/Cbic.200700408  1
2007 Prasad AK, Kalra N, Yadav Y, Singh SK, Sharma SK, Patkar S, Lange L, Olsen CE, Wengel J, Parmar VS. Selective biocatalytic deacylation studies on furanose triesters: a novel and efficient approach towards bicyclonucleosides. Organic & Biomolecular Chemistry. 5: 3524-30. PMID 17943213 DOI: 10.1039/b711455a  1
2007 Bramsen JB, Laursen MB, Damgaard CK, Lena SW, Babu BR, Wengel J, Kjems J. Improved silencing properties using small internally segmented interfering RNAs Nucleic Acids Research. 35: 5886-5897. PMID 17726057 DOI: 10.1093/Nar/Gkm548  1
2007 Kalek M, Madsen AS, Wengel J. Effective modulation of DNA duplex stability by reversible transition metal complex formation in the minor groove. Journal of the American Chemical Society. 129: 9392-400. PMID 17616191 DOI: 10.1021/Ja071076Z  1
2007 Kalek M, Madsen AS, Wengel J. Effective modulation of DNA duplex stability by reversible transition metal complex formation in the minor groove. Journal of the American Chemical Society. 129: 9392-400. PMID 17616191 DOI: 10.1021/Ja071076Z  1
2007 Prasad AK, Kalra N, Yadav Y, Kumar R, Sharma SK, Patkar S, Lange L, Wengel J, Parmar VS. Deacylation studies on furanose triesters using an immobilized lipase: synthesis of a key precursor for bicyclonucleosides. Chemical Communications (Cambridge, England). 2616-7. PMID 17579756 DOI: 10.1039/b618426j  1
2007 Kumar TS, Wengel J, Hrdlicka PJ. 2'-N-(pyren-1-yl)acetyl-2'-amino-alpha-L-LNA: synthesis and detection of single nucleotide mismatches in DNA and RNA targets. Chembiochem : a European Journal of Chemical Biology. 8: 1122-5. PMID 17551917 DOI: 10.1002/Cbic.200700144  1
2007 Grubb M, Wackerbarth H, Wengel J, Ulstrup J. Direct imaging of hexaamine-ruthenium(III) in domain boundaries in monolayers of single-stranded DNA. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 1410-3. PMID 17241066 DOI: 10.1021/La062555Z  1
2006 Vester B, Hansen LH, Lundberg LB, Babu BR, Sørensen MD, Wengel J, Douthwaite S. Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets. Bmc Molecular Biology. 7: 19. PMID 16753066 DOI: 10.1186/1471-2199-7-19  1
2006 Madsen AS, Hrdlicka PJ, Kumar TS, Wengel J. Synthesis, nucleic acid hybridization properties and molecular modelling studies of conformationally restricted 3'-O,4'-C-methylene-linked alpha-L-ribonucleotides. Carbohydrate Research. 341: 1398-407. PMID 16709404 DOI: 10.1016/J.Carres.2006.04.010  1
2006 Kumar TS, Madsen AS, Wengel J, Hrdlicka PJ. Synthesis and hybridization studies of 2'-amino-alpha-L-LNA and tetracyclic "locked LNA". The Journal of Organic Chemistry. 71: 4188-201. PMID 16709060 DOI: 10.1021/Jo060331F  1
2006 Lindegaard D, Wood DO, Wengel J, Lee JS. Electron injection from the side of an M-DNA duplex. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 11: 82-7. PMID 16328459 DOI: 10.1007/S00775-005-0052-Y  1
2006 Wackerbarth H, Grubb M, Wengel J, Chorkendorff I, Ulstrup J. Adsorption and surface dynamics of short DNA and LNA oligonucleotides on single-crystal Au(1 1 1) electrode surfaces Surface Science. 600: 122-127. DOI: 10.1016/J.Susc.2006.03.009  1
2005 Hrdlicka PJ, Kumar TS, Wengel J. Synthesis of a 2'-amino-alpha-1-LNA-T phosphoramidite. Nucleosides, Nucleotides & Nucleic Acids. 24: 1101-4. PMID 16248100 DOI: 10.1080/15257770500276866  1
2005 Hrdlicka PJ, Jepsen JS, Wengel J. Synthesis and biological evaluation of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-C-ethynylcytidine (ECyd). Nucleosides, Nucleotides & Nucleic Acids. 24: 397-400. PMID 16247958 DOI: 10.1081/Ncn-200059821  1
2005 Hrdlicka PJ, Babu BR, Sørensen MD, Harrit N, Wengel J. Multilabeled pyrene-functionalized 2'-amino-LNA probes for nucleic acid detection in homogeneous fluorescence assays. Journal of the American Chemical Society. 127: 13293-9. PMID 16173760 DOI: 10.1021/Ja052887A  1
2005 Hrdlicka PJ, Kumar TS, Wengel J. Targeting of mixed sequence double-stranded DNA using pyrene-functionalized 2'-amino-alpha-l-LNA. Chemical Communications (Cambridge, England). 4279-81. PMID 16113721 DOI: 10.1039/B506986F  1
2005 Brunet E, Corgnali M, Perrouault L, Roig V, Asseline U, Sørensen MD, Babu BR, Wengel J, Giovannangeli C. Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities. Nucleic Acids Research. 33: 4223-34. PMID 16049028 DOI: 10.1093/nar/gki726  1
2005 Babu BR, Hrdlicka PJ, McKenzie CJ, Wengel J. Optimized DNA targeting using N,N-bis(2-pyridylmethyl)-beta-alanyl 2'-amino-LNA. Chemical Communications (Cambridge, England). 1705-7. PMID 15791305 DOI: 10.1039/B417101B  1
2005 Hrdlicka PJ, Andersen NK, Jepsen JS, Hansen FG, Haselmann KF, Nielsen C, Wengel J. Synthesis and biological evaluation of branched and conformationally restricted analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd). Bioorganic & Medicinal Chemistry. 13: 2597-621. PMID 15755661 DOI: 10.1016/J.Bmc.2005.01.029  1
2005 Hrdlicka PJ, Jepsen JS, Nielsen C, Wengel J. Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd). Bioorganic & Medicinal Chemistry. 13: 1249-60. PMID 15670934 DOI: 10.1016/J.Bmc.2004.11.054  1
2005 Babu BR, Raunak, Sørensen MD, Hrdlicka PJ, Trikha S, Prasad AK, Parmar VS, Wengel J. Novel nucleic acid architecture involving locked nucleic acid (LNA) and pyrene residues: Results from an Indo-Danish collaboration Pure and Applied Chemistry. 77: 319-326. DOI: 10.1351/Pac200577010319  1
2005 Hrdlicka PJ, Babu BR, Sørensen MD, Harrit N, Wengel J. Ångström-scale chemical engineering: Multilabeled 2'-amino-LNA probes for nucleic acid detection in homogenous fluorescence assays Collection of Czechoslovak Chemical Communications. 7: 27-28. DOI: 10.1135/Css200507027  1
2005 Hrdlicka PJ, Kumar TS, Wengel J. Synthesis and thermal denaturation studies of conformationally restricted 3′-C-ethynyl-3′-O,4′-C-methyleneribonucleotides European Journal of Organic Chemistry. 5184-5188. DOI: 10.1002/Ejoc.200500379  1
2004 Jepsen JS, Sørensen MD, Wengel J. Locked nucleic acid: a potent nucleic acid analog in therapeutics and biotechnology. Oligonucleotides. 14: 130-46. PMID 15294076 DOI: 10.1089/1545457041526317  1
2004 Hrdlicka PJ, Babu BR, Sørensen MD, Wengel J. Interstrand communication between 2'-N-(pyren-1-yl)methyl-2'-amino-LNA monomers in nucleic acid duplexes: directional control and signalling of full complementarity. Chemical Communications (Cambridge, England). 1478-9. PMID 15216339 DOI: 10.1039/B404446K  1
2004 Sun BW, Babu BR, Sørensen MD, Zakrzewska K, Wengel J, Sun JS. Sequence and pH effects of LNA-containing triple helix-forming oligonucleotides: physical chemistry, biochemistry, and modeling studies. Biochemistry. 43: 4160-9. PMID 15065859 DOI: 10.1021/bi036064e  1
2004 Crinelli R, Bianchi M, Gentilini L, Palma L, Sørensen MD, Bryld T, Babu RB, Arar K, Wengel J, Magnani M. Transcription factor decoy oligonucleotides modified with locked nucleic acids: an in vitro study to reconcile biostability with binding affinity. Nucleic Acids Research. 32: 1874-85. PMID 15051810 DOI: 10.1093/nar/gkh503  1
2004 Vester B, Lundberg LB, Sørensen MD, Babu BR, Douthwaite S, Wengel J. Improved RNA cleavage by LNAzyme derivatives of DNAzymes. Biochemical Society Transactions. 32: 37-40. PMID 14748708 DOI: 10.1042/  1
2004 Raunak, Ravindra Babu B, Sørensen MD, Parmar VS, Harrit NH, Wengel J. Oligodeoxynucleotides containing alpha-L-ribo configured LNA-type C-aryl nucleotides. Organic & Biomolecular Chemistry. 2: 80-9. PMID 14737663 DOI: 10.1039/b310719a  1
2003 Arzumanov A, Stetsenko DA, Malakhov AD, Reichelt S, Sørensen MD, Babu BR, Wengel J, Gait MJ. A structure-activity study of the inhibition of HIV-1 Tat-dependent trans-activation by mixmer 2'-O-methyl oligoribonucleotides containing locked nucleic acid (LNA), alpha-L-LNA, or 2'-thio-LNA residues. Oligonucleotides. 13: 435-53. PMID 15025911 DOI: 10.1089/154545703322860762  1
2003 Christensen SM, Rosenbohm C, Sørensen M, Larsen LE, Wengel J, Koch T. Improved synthesis of 2′-amino-LNA Nucleosides, Nucleotides and Nucleic Acids. 22: 1131-1133. PMID 14565362 DOI: 10.1081/NCN-120022818  1
2003 Wengel J, Vester B, Lundberg LB, Douthwaite S, Sørensen MD, Babu BR, Gait MJ, Arzumanov A, Petersen M, Nielsen JT. LNA and alpha-L-LNA: towards therapeutic applications. Nucleosides, Nucleotides & Nucleic Acids. 22: 601-4. PMID 14565236 DOI: 10.1081/NCN-120021963  1
2003 Rosenbohm C, Christensen SM, Sørensen MD, Pedersen DS, Larsen LE, Wengel J, Koch T. Synthesis of 2'-amino-LNA: a new strategy. Organic & Biomolecular Chemistry. 1: 655-63. PMID 12929452  1
2003 Poopeiko NE, Juhl M, Vester B, Sørensen MD, Wengel J. Xylo-Configured oligonucleotides (XNA, xylo nucleic acid): synthesis of conformationally restricted derivatives and hybridization towards DNA and RNA complements. Bioorganic & Medicinal Chemistry Letters. 13: 2285-90. PMID 12824019 DOI: 10.1016/S0960-894X(03)00441-4  1
2002 Vester B, Lundberg LB, Sørensen MD, Babu BR, Douthwaite S, Wengel J. LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage. Journal of the American Chemical Society. 124: 13682-3. PMID 12431091 DOI: 10.1021/ja0276220  1
2001 Sørensen MD, Kvaernø L, Bryld T, Håkansson AE, Keinicke L, Verbeure B, Herdewijn P, Wengel J. The alpha-L-ribo-isomers of RNA and LNA (locked nucleic acid). Nucleic Acids Research. Supplement (2001). 25-6. PMID 12836246 DOI: 10.1093/nass/1.1.25  1
2001 Arzumanov A, Walsh AP, Rajwanshi VK, Kumar R, Wengel J, Gait MJ. Inhibition of HIV-1 Tat-dependent trans activation by steric block chimeric 2'-O-methyl/LNA oligoribonucleotides. Biochemistry. 40: 14645-54. PMID 11724578 DOI: 10.1021/BI011279E  1
2001 Wengel J, Petersen M, Nielsen KE, Jensen GA, Håkansson AE, Kumar R, Sørensen MD, Rajwanshi VK, Bryld T, Jacobsen JP. LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: conformational tuning and high-affinity recognition of DNA/RNA targets. Nucleosides, Nucleotides & Nucleic Acids. 20: 389-96. PMID 11563053 DOI: 10.1081/NCN-100002312  1
2001 Egli M, Minasov G, Teplova M, Kumar R, Wengel J. X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer Journal of the Chemical Society, Chemical Communications. 651-652. DOI: 10.2210/Pdb1I5W/Pdb  1
2001 Egli M, Minasov G, Teplova M, Kumar R, Wengel J. X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer Chemical Communications. 2001: 651-652. DOI: 10.1039/B009447L  1
2000 Rajwanshi VK, Håkansson AE, Sørensen MD, Pitsch S, Singh SK, Kumar R, Nielsen P, Wengel J. The Eight Stereoisomers of LNA (Locked Nucleic Acid): A Remarkable Family of Strong RNA Binding Molecules We acknowledge the Danish Natural Science Research Council, the Danish Technical Research Council, and Exiqon A/S for financial support. Ms Britta M. Dahl is thanked for oligonucleotide synthesis, Dr. Carl E. Olsen for MALDI-MS analysis, and Ms. Karen Jørgensen for recording CD spectra. Angewandte Chemie (International Ed. in English). 39: 1656-1659. PMID 10820467 DOI: 10.1002/(SICI)1521-3773(20000502)39:9<1656::AID-ANIE1656>3.0.CO;2-Q  1
2000 Wahlestedt C, Salmi P, Good L, Kela J, Johnsson T, Hökfelt T, Broberger C, Porreca F, Lai J, Ren K, Ossipov M, Koshkin A, Jakobsen N, Skouv J, Oerum H, ... ... Wengel J, et al. Potent and nontoxic antisense oligonucleotides containing locked nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 97: 5633-8. PMID 10805816 DOI: 10.1073/pnas.97.10.5633  1
2000 Petersen M, Nielsen CB, Nielsen KE, Jensen GA, Bondensgaard K, Singh SK, Rajwanshi VK, Koshkin AA, Dahl BM, Wengel J, Jacobsen JP. The conformations of locked nucleic acids (LNA). Journal of Molecular Recognition : Jmr. 13: 44-53. PMID 10679896 DOI: 10.1002/(SICI)1099-1352(200001/02)13:1<44::AID-JMR486>3.0.CO;2-6  1
1999 Nielsen CB, Singh SK, Wengel J, Jacobsen JP. The solution structure of a locked nucleic acid (LNA) hybridized to DNA. Journal of Biomolecular Structure & Dynamics. 17: 175-91. PMID 10563569 DOI: 10.1080/07391102.1999.10508352  1
1999 Raj HG, Parmar VS, Jain SC, Priyadarsini KI, Mittal JP, Goel S, Das SK, Sharma SK, Olsen CE, Wengel J. Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 5: Pulse radiolysis studies on the antioxidant action of 7,8-diacetoxy-4-methylcoumarin. Bioorganic & Medicinal Chemistry. 7: 2091-4. PMID 10530959 DOI: 10.1016/S0968-0896(99)00174-1  1
1998 Raj HG, Sharma RK, Garg BS, Parmar VS, Jain SC, Goel S, Tyagi YK, Singh A, Olsen CE, Wengel J. Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 3: A novel mechanism for the inhibition of biological membrane lipid peroxidation by dioxygenated 4-methylcoumarins mediated by the formation of a stable ADP-Fe-inhibitor mixed ligand complex. Bioorganic & Medicinal Chemistry. 6: 2205-12. PMID 9881111 DOI: 10.1016/S0968-0896(98)00159-X  1
1998 Raj HG, Parmar VS, Jain SC, Goel S, Poonam, Himanshu, Malhotra S, Singh A, Olsen CE, Wengel J. Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part I: Dioxygenated 4-methyl coumarins as superb antioxidant and radical scavenging agents. Bioorganic & Medicinal Chemistry. 6: 833-9. PMID 9681149 DOI: 10.1016/S0968-0896(98)00043-1  1
1997 Parmar VS, Bracke ME, Philippe J, Wengel J, Jain SC, Olsen CE, Bisht KS, Sharma NK, Courtens A, Sharma SK, Vennekens K, Van Marck V, Singh SK, Kumar N, Kumar A, et al. Anti-invasive activity of alkaloids and polyphenolics in vitro. Bioorganic & Medicinal Chemistry. 5: 1609-19. PMID 9313866 DOI: 10.1016/S0968-0896(97)00091-6  1
1997 Parmar VS, Jain SC, Bisht KS, Jain R, Taneja P, Jha A, Tyagi OD, Prasad AK, Wengel J, Olsen CE, Boll PM. Phytochemistry of the genus Piper Phytochemistry. 46: 597-673. DOI: 10.1016/S0031-9422(97)00328-2  1
1996 Gotfredsen CH, Spielmann HP, Wengel J, Jacobsen JP. Structure of a DNA duplex containing a single 2'-O-methyl-beta-D-araT: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement. Bioconjugate Chemistry. 7: 680-8. PMID 8950487 DOI: 10.1021/bc960061f  1
1996 Parmar VS, Bisht KS, Pati HN, Sharma NK, Kumar A, Kumar N, Malhotra S, Singh A, Prasad AK, Wengel J. Novel biotransformations on peracylated polyphenolics by immobilized lipases in microemulsion-based gels and on carbohydrates by Candida antartica lipase Pure and Applied Chemistry. 68: 1309-1314. DOI: 10.1351/Pac199668061309  1
1996 Boll PM, Prasad AK, Tyagi OD, Wengel J, Olsen CE, Kumar N, Bisht KS, Parmar VS. Neolignans, cyclohexanes and alkaloids from Piper wightii Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands. 115: 9-12. DOI: 10.1002/Recl.19961150103  1
1995 Nielsen KD, Kirpekar F, Roepstorff P, Wengel J. Oligonucleotide analogues containing 4′-C-(Hydroxymethyl)uridine: Synthesis, evaluation and mass spectrometric analysis Bioorganic and Medicinal Chemistry. 3: 1493-1502. PMID 8634829 DOI: 10.1016/0968-0896(95)00138-7  1
1995 Wengel J, Schinazi RF, Caruthers MH. Stereoselective synthesis, chemistry and antiviral evaluation of 1-(2,3-dideoxy-3-C-hydroxymethyl-beta-D-threo-pentofuranosyl)thymine derivatives. Bioorganic & Medicinal Chemistry. 3: 1223-9. PMID 8564413 DOI: 10.1016/0968-0896(95)00089-Y  1
1995 Raj HG, Gupta S, Prasad AK, Boll PM, Wengel J, Biswas G, Singh SK, Sharma NK, Bisht KS, Parmar VS. Methylenedioxyphenyl substituted compounds from Piper species as inhibitors of liver microsome-mediated aflatoxin B1-DNA binding in vitro Bioorganic and Medicinal Chemistry Letters. 5: 1567-1572. DOI: 10.1016/0960-894X(95)00272-U  1
1995 Prasad AK, Sørensen MD, Parmar VS, Wengel J. Tri-O-acyl 2-deoxy-D-ribofuranose: An effective enzyme-assisted one-pot synthesis from 2-deoxy-D-ribose and transformation into 2′-deoxynucleosides Tetrahedron Letters. 36: 6163-6166. DOI: 10.1016/0040-4039(95)01216-5  1
1995 Prasad AK, Tyagi OD, Wengel J, Boll PM, Olsen CE, Bisht KS, Singh A, Sarangi A, Kumar R, Jain SC, Parmar VS. Neolignans and a lignan from Piper clarkii Phytochemistry. 39: 655-658. DOI: 10.1016/0031-9422(95)00036-7  1
1994 Prasad AK, Tyagi OD, Wengel J, Boll PM, Olsen CE, Gupta S, Sharma NK, Bisht KS, Parmar VS. Lignans and neolignans from stems of Piper wightii Tetrahedron. 50: 10579-10586. DOI: 10.1016/S0040-4020(01)89597-1  1
1992 Wengel J, Motawia MS, Pedersen EB, Nielsen CM. Analogues of the antibiotic puromycin as potential prodrugs of 3′‐amino‐3′‐deoxythymidine Journal of Heterocyclic Chemistry. 29: 5-9. DOI: 10.1002/jhet.5570290102  1
1991 Prasad AK, Tyagi OD, Wengel J, Boll PM, Olsen CE, Sharma NK, Bisht KS, Gupta S, Parmar VS. Lignans and neolignans from stems and fruits of Piper wightii Tetrahedron. 50: 2231-2240. DOI: 10.1016/S0040-4020(01)85081-X  1
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