Jonathan R. Chekan - Related publications

Affiliations: 
2020- UNC Greensboro, Greensboro, NC, United States 
Area:
Peptide chemistry
Website:
https://chem.uncg.edu/chekan/
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Song I, Kim Y, Yu J, Go SY, Lee HG, Song WJ, Kim S. Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB. Nature Chemical Biology. PMID 34475564 DOI: 10.1038/s41589-021-00855-x   
2021 Jia Q, Zeng H, Li H, Xiao N, Tang J, Gao S, Zhang J, Xie W. The C-terminal loop of guanosine deaminase is essential to catalysis. Chemical Communications (Cambridge, England). PMID 34477187 DOI: 10.1039/d1cc03042f   
2021 Somma V, Calvio C, Rabuffetti M, Rama E, Speranza G, Morelli CF. An overall framework for the E. coli γ-glutamyltransferase-catalyzed transpeptidation reactions. Bioorganic Chemistry. 115: 105217. PMID 34364051 DOI: 10.1016/j.bioorg.2021.105217   
2021 Wei X, Matsuyama T, Sato H, Yan D, Chan PM, Miyamoto K, Uchiyama M, Matsuda Y. Molecular and Computational Bases for Spirofuranone Formation in Setosusin Biosynthesis. Journal of the American Chemical Society. PMID 34644070 DOI: 10.1021/jacs.1c08336   
2021 Vinogradov AA, Nagano M, Goto Y, Suga H. Site-Specific Nonenzymatic Peptide S/O-Glutamylation Reveals the Extent of Substrate Promiscuity in Glutamate Elimination Domains. Journal of the American Chemical Society. 143: 13358-13369. PMID 34392675 DOI: 10.1021/jacs.1c06470   
2021 Erickson E, Shakespeare TJ, Bratti F, Buss BL, Graham R, Hawkins MA, König G, Michener WE, Miscall J, Ramirez KJ, Rorrer NA, Zahn M, Pickford AR, McGeehan JE, Beckham G. Comparative performance of PETase as a function of reaction conditions, substrate properties, and product accumulation. Chemsuschem. PMID 34587366 DOI: 10.1002/cssc.202101932   
2021 Little RF, Hertweck C. Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis. Natural Product Reports. PMID 34622896 DOI: 10.1039/d1np00035g   
2021 Bakunova AK, Nikolaeva AY, Rakitina TV, Isaikina TY, Khrenova MG, Boyko KM, Popov VO, Bezsudnova EY. The Uncommon Active Site of D-Amino Acid Transaminase from : Biochemical and Structural Insights into the New Enzyme. Molecules (Basel, Switzerland). 26. PMID 34443642 DOI: 10.3390/molecules26165053   
2021 Kummer MJ, Lee YS, Yuan M, Alkotaini B, Zhao J, Blumenthal E, Minteer SD. Substrate Channeling by a Rationally Designed Fusion Protein in a Biocatalytic Cascade. Jacs Au. 1: 1187-1197. PMID 34467357 DOI: 10.1021/jacsau.1c00180   
2021 Tegl G, Rahfeld P, Ostmann K, Hanson J, Withers SG. Discovery of β--acetylglucosaminidases from screening metagenomic libraries and their use as thioglycoligase mutants. Organic & Biomolecular Chemistry. PMID 34622263 DOI: 10.1039/d1ob01246k   
2021 Arias-Orozco P, Inklaar M, Lanooij J, Cebrián R, Kuipers OP. Functional Expression and Characterization of the Highly Promiscuous Lanthipeptide Synthetase SyncM, Enabling the Production of Lanthipeptides with a Broad Range of Ring Topologies. Acs Synthetic Biology. PMID 34554737 DOI: 10.1021/acssynbio.1c00224   
2021 Washburn LA, Nepal KK, Watanabe CMH. A Capture Strategy for the Identification of Thio-Templated Metabolites. Acs Chemical Biology. PMID 34423966 DOI: 10.1021/acschembio.1c00437   
2021 Guo J, Wang Y, Gao W, Wang X, Gao X, Man Z, Cai Z, Qing Q. Gene Cloning, Functional Expression, and Characterization of a Novel GH46 Chitosanase from Streptomyces avermitilis (SaCsn46A). Applied Biochemistry and Biotechnology. PMID 34542822 DOI: 10.1007/s12010-021-03687-6   
2021 Wang Y, Mittermaier AK. Characterizing Bi-substrate Enzyme Kinetics at High Resolution by 2D-ITC. Analytical Chemistry. PMID 34514786 DOI: 10.1021/acs.analchem.1c02705   
2021 Espina G, Atalah J, Blamey JM. Extremophilic Oxidoreductases for the Industry: Five Successful Examples With Promising Projections. Frontiers in Bioengineering and Biotechnology. 9: 710035. PMID 34458243 DOI: 10.3389/fbioe.2021.710035   
2021 Li Q, Pan Y, Li H, Lenertz M, Reed K, Jordahl D, Bjerke T, Ugrinov A, Chen B, Yang Z. Cascade/Parallel Biocatalysis via Multi-enzyme Encapsulation on Metal-Organic Materials for Rapid and Sustainable Biomass Degradation. Acs Applied Materials & Interfaces. PMID 34478257 DOI: 10.1021/acsami.1c12209   
2021 Wu H, Chen Q, Zhang W, Mu W. Overview of strategies for developing high thermostability industrial enzymes: Discovery, mechanism, modification and challenges. Critical Reviews in Food Science and Nutrition. 1-18. PMID 34445912 DOI: 10.1080/10408398.2021.1970508   
2021 Prasher P, Sharma M. Medicinal chemistry of pyrophosphate mimics: A mini review. Drug Development Research. PMID 34506652 DOI: 10.1002/ddr.21877   
2021 Kuriya Y, Inoue M, Yamamoto M, Murata M, Araki M. Knowledge extraction from literatures and enzyme sequences complements FBA analysis in metabolic engineering. Biotechnology Journal. e2000443. PMID 34516717 DOI: 10.1002/biot.202000443   
2021 Wang Y, Hanrahan G, Azar FA, Mittermaier A. Binding interactions in a kinase active site modulate background ATP hydrolysis. Biochimica Et Biophysica Acta. Proteins and Proteomics. 140720. PMID 34597835 DOI: 10.1016/j.bbapap.2021.140720   
2021 Padavattan S, Jos S, Gogoi H, Bagautdinov B. Crystal structure of enoyl-CoA hydratase from Thermus thermophilus HB8. Acta Crystallographica. Section F, Structural Biology Communications. 77: 148-155. PMID 33949975 DOI: 10.1107/S2053230X21004593   
2021 Xu A, Zhang X, Wu S, Xu N, Huang Y, Yan X, Zhou J, Cui Z, Dong W. Pollutant Degrading Enzyme: Catalytic Mechanisms and Their Expanded Applications. Molecules (Basel, Switzerland). 26. PMID 34443339 DOI: 10.3390/molecules26164751   
2021 Chan PWY, Chakrabarti N, Ing C, Halgas O, To TKW, Wälti M, Petit AP, Tran C, Savchenko A, Yakunin AF, Edwards EA, Pomès R, Pai EF. Defluorination Capability of l-2-Haloacid Dehalogenases in the HAD-like Hydrolase Superfamily Correlates with Active Site Compactness. Chembiochem : a European Journal of Chemical Biology. PMID 34643018 DOI: 10.1002/cbic.202100414   
2021 Currie MJ, Manjunath L, Horne CR, Rendle PM, Subramanian R, Friemann R, Fairbanks AJ, Muscroft-Taylor AC, North RA, Dobson RCJ. N-Acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization. The Journal of Biological Chemistry. 101113. PMID 34437902 DOI: 10.1016/j.jbc.2021.101113   
2021 Bose I, Zhao Y. Selective Hydrolysis of Aryl Esters under Acidic and Neutral Conditions by a Synthetic Aspartic Protease Mimic. Acs Catalysis. 11: 3938-3942. PMID 34422449 DOI: 10.1021/acscatal.1c00371   
2021 Singh A, Joseph JP, Gupta D, Miglani C, Mavlankar NA, Pal A. Photothermally switchable peptide nanostructures towards modulating catalytic hydrolase activity. Nanoscale. 13: 13401-13409. PMID 34477745 DOI: 10.1039/d1nr03655f   
2021 Wang J, Anderson K, Yang E, He L, Lidstrom ME. Enzyme engineering and testing of a formate reduction pathway. Synthetic Biology (Oxford, England). 6: ysab020. PMID 34651085 DOI: 10.1093/synbio/ysab020   
2021 Heid E, Goldman S, Sankaranarayanan K, Coley CW, Flamm C, Green WH. EHreact: Extended Hasse Diagrams for the Extraction and Scoring of Enzymatic Reaction Templates. Journal of Chemical Information and Modeling. PMID 34587449 DOI: 10.1021/acs.jcim.1c00921   
2021 Tohar R, Ansbacher T, Sher I, Afriat-Jurnou L, Weinberg E, Gal M. Screening Collagenase Activity in Bacterial Lysate for Directed Enzyme Applications. International Journal of Molecular Sciences. 22. PMID 34445258 DOI: 10.3390/ijms22168552   
2021 Pei X, Wang J, Zheng H, Xiao Q, Wang A, Su W. Catalytically active inclusion bodies (CatIBs) induced by terminally attached self-assembling coiled-coil domains: To enhance the stability of (R)-hydroxynitrile lyase. Enzyme and Microbial Technology. 153: 109915. PMID 34670185 DOI: 10.1016/j.enzmictec.2021.109915   
2021 Hong K, Wang L, Johnpaul A, Lv C, Ma C. Key Enzymes Involved in the Synthesis of Hops Phytochemical Compounds: From Structure, Functions to Applications. International Journal of Molecular Sciences. 22. PMID 34502286 DOI: 10.3390/ijms22179373   
2021 Hayashi D, Mouchlis VD, Dennis EA. Omega-3 Versus Omega-6 Fatty Acid Availability is Controlled by Hydrophobic Site Geometries of Phospholipase As. Journal of Lipid Research. 100113. PMID 34474084 DOI: 10.1016/j.jlr.2021.100113   
2021 Eusebio N, Rego A, Glasser NR, Castelo-Branco R, Balskus EP, Leão PN. Distribution and diversity of dimetal-carboxylate halogenases in cyanobacteria. Bmc Genomics. 22: 633. PMID 34461836 DOI: 10.1186/s12864-021-07939-x   
2021 Zhang YX, Yang JW, Wu YY, Hu XQ, Zhang HB. The stability improvement of dextransucrase by artificial extension modification of the V domain of the enzyme. Enzyme and Microbial Technology. 151: 109919. PMID 34649690 DOI: 10.1016/j.enzmictec.2021.109919   
2021 Thompson NK, LeClaire L, Rodriguez Perez S, Wakarchuk W. Investigation of sequon engineering for improved O-glycosylation by the human polypeptide N-acetylgalactosaminyl transferase T2 isozyme and two orthologues. The Biochemical Journal. PMID 34523671 DOI: 10.1042/BCJ20210382   
2021 Dai L, Chang Z, Yang J, Liu W, Yang Y, Chen CC, Zhang L, Huang JW, Sun Y, Guo RT. Structural investigation of a thermostable 1,2-β-mannobiose phosphorylase from Thermoanaerobacter sp. X-514. Biochemical and Biophysical Research Communications. 579: 54-61. PMID 34587555 DOI: 10.1016/j.bbrc.2021.09.046   
2021 Wang Q, Zhang L. Harnessing P450 enzyme for biotechnology and synthetic biology. Chembiochem : a European Journal of Chemical Biology. PMID 34542923 DOI: 10.1002/cbic.202100439   
2021 Wang J, Su P, Gao L, Zhang Y, Wang J, Tu L, Zhao Y, Lu Y, Yin Y, Huang L, Gao W. A cytochrome P450 CYP81AM1 from Tripterygium wilfordii catalyses the C-15 hydroxylation of dehydroabietic acid. Planta. 254: 95. PMID 34643823 DOI: 10.1007/s00425-021-03743-9   
2021 Nowak MG, Skwarecki AS, Milewska MJ. Amino Acid Based Antimicrobial Agents - Synthesis and Properties. Chemmedchem. PMID 34596961 DOI: 10.1002/cmdc.202100503   
2021 Mori T, Zhai R, Ushimaru R, Matsuda Y, Abe I. Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI. Nature Communications. 12: 4417. PMID 34285212 DOI: 10.1038/s41467-021-24685-6   
2021 Feller FM, Richtsmeier P, Wege M, Philipp B. Comparative analysis of bile-salt degradation in sp. strain Chol11 and Chol1 reveals functional diversity of proteobacterial steroid degradation enzymes and suggests a novel pathway for side-chain degradation. Applied and Environmental Microbiology. AEM0145321. PMID 34469190 DOI: 10.1128/AEM.01453-21   
2021 Cheng F, Zhai QY, Gao XF, Liu HT, Qiu S, Wang YJ, Zheng YG. Tuning enzymatic properties by protein engineering toward catalytic tetrad of carbonyl reductase. Biotechnology and Bioengineering. PMID 34436762 DOI: 10.1002/bit.27925   
2021 Li T, Gao YZ, Xu J, Zhang ST, Guo Y, Spain JC, Zhou NY. A Recently Assembled Degradation Pathway for 2,3-Dichloronitrobenzene in sp. Strain JS3051. Mbio. e0223121. PMID 34425699 DOI: 10.1128/mBio.02231-21   
2021 Kumar A, Mukhia S, Kumar R. Industrial applications of cold-adapted enzymes: challenges, innovations and future perspective. 3 Biotech. 11: 426. PMID 34567931 DOI: 10.1007/s13205-021-02929-y   
2021 Ali A, Ellinger B, Brandt SC, Betzel C, Rühl M, Wrenger C, Schlüter H, Schäfer W, Brognaro H, Gand M. Genome and Secretome Analysis of DSM105789 Cultured on Agro-Residual and Chitinous Biomass. Microorganisms. 9. PMID 34442660 DOI: 10.3390/microorganisms9081581   
2021 Zaru R, Onwubiko J, Ribeiro AJM, Cochrane K, Tyzack JD, Muthukrishnan V, Pravda L, Thornton JM, O'Donovan C, Velanker S, Orchard S, Leach A, Martin MJ. The Enzyme Portal: an integrative tool for enzyme information and analysis. The Febs Journal. PMID 34437766 DOI: 10.1111/febs.16168   
2021 Wang Z, Huang X, Liu J, Xiao F, Tian M, Ding S, Shan Y. Screening and heterologous expression of flavone synthase and flavonol synthase to catalyze hesperetin to diosmetin. Biotechnology Letters. PMID 34514540 DOI: 10.1007/s10529-021-03184-0   
2021 Chen Y, Wu J, Yu D, Du X. Advances in steroidal saponins biosynthesis. Planta. 254: 91. PMID 34617240 DOI: 10.1007/s00425-021-03732-y   
2021 Campomizzi CS, Ghanatios GE, Estrada DF. F-NMR reveals substrate specificity of CYP121A1 in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 101287. PMID 34634307 DOI: 10.1016/j.jbc.2021.101287   
2021 Gabrielli V, Muñoz-García JC, Pergolizzi G, de Andrade P, Khimyak Y, Field RA, Angulo J. Molecular recognition of natural and non-natural substrates by cellodextrin phosphorylase from Ruminiclostridium thermocellum investigated by NMR spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34436794 DOI: 10.1002/chem.202102039