Satish K. Nair - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Natural products biosynthesis, bacterial signalling, X-ray crystallography
Website:
https://mcb.illinois.edu/faculty/profile/snair/

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Grigoreva A, Andreeva J, Bikmetov D, Rusanova A, Serebryakova M, Garcia AH, Slonova D, Nair SK, Lippens G, Severinov K, Dubiley S. Identification and characterization of andalusicin: N-terminally dimethylated class III lantibiotic from sv. . Iscience. 24: 102480. PMID 34113822 DOI: 10.1016/j.isci.2021.102480  0.01
2021 Simon MA, Ongpipattanakul C, Nair SK, van der Donk WA. Biosynthesis of fosfomycin in pseudomonads reveals an unexpected enzymatic activity in the metallohydrolase superfamily. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34074759 DOI: 10.1073/pnas.2019863118  1
2021 Lai KY, Galan SRG, Zeng Y, Zhou TH, He C, Raj R, Riedl J, Liu S, Chooi KP, Garg N, Zeng M, Jones LH, Hutchings GJ, Mohammed S, Nair SK, et al. LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome. Cell. PMID 33932340 DOI: 10.1016/j.cell.2021.04.001  1
2021 Griffin SL, Chekan JR, Lira JM, Robinson AE, Yerkes CN, Siehl DL, Wright TR, Nair SK, Cicchillo RM. Characterization of a Glyphosate-Tolerant Enzyme from : A Distinct Class of 5-Enolpyruvylshikimate-3-phosphate Synthases. Journal of Agricultural and Food Chemistry. PMID 33826316 DOI: 10.1021/acs.jafc.1c00439  1
2021 Liu A, Si Y, Dong SH, Mahanta N, Penkala HN, Nair SK, Mitchell DA. Functional elucidation of TfuA in peptide backbone thioamidation. Nature Chemical Biology. PMID 33707784 DOI: 10.1038/s41589-021-00771-0  0.01
2020 Cogan DP, Ly J, Nair SK. Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation. Acs Chemical Biology. PMID 33017142 DOI: 10.1021/acschembio.0c00579  0.01
2020 Montalbán-López M, Scott TA, Ramesh S, Rahman IR, van Heel AJ, Viel JH, Bandarian V, Dittmann E, Genilloud O, Goto Y, Grande Burgos MJ, Hill C, Kim S, Koehnke J, Latham JA, ... ... Nair SK, et al. New developments in RiPP discovery, enzymology and engineering. Natural Product Reports. PMID 32935693 DOI: 10.1039/D0Np00027B  1
2020 Bogart JW, Kramer NJ, Turlik A, Bleich RM, Catlin DS, Schroeder FC, Nair SK, Williamson RT, Houk KN, Bowers AA. Interception of the "Bycroft-Gowland" intermediate in the enzymatic macrocyclization of thiopeptides. Journal of the American Chemical Society. PMID 32609512 DOI: 10.1021/Jacs.0C05639  0.01
2020 Kapoor I, Olivares P, Nair SK. Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones. Elife. 9. PMID 32510324 DOI: 10.7554/eLife.57824  1
2020 Dong SH, Nhu-Lam M, Nagarajan R, Nair SK. Structure-Guided Biochemical Analysis of Quorum Signal Synthase Specificities. Acs Chemical Biology. PMID 32356962 DOI: 10.1021/Acschembio.0C00142  0.01
2020 Nayak DD, Liu A, Agrawal N, Rodriguez-Carerro R, Dong SH, Mitchell DA, Nair SK, Metcalf WW. Functional interactions between posttranslationally modified amino acids of methyl-coenzyme M reductase in Methanosarcina acetivorans. Plos Biology. 18: e3000507. PMID 32092071 DOI: 10.1371/Journal.Pbio.3000507  0.01
2019 Nair SK, Jez JM. Natural product biosynthesis:  What's next?  An introduction to the JBC Reviews Thematic Series. The Journal of Biological Chemistry. PMID 31806701 DOI: 10.1074/Jbc.Rev119.011586  0.01
2019 Chekan JR, Ongpipattanakul C, Nair SK. Steric complementarity directs sequence promiscuous leader binding in RiPP biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 116: 24049-24055. PMID 31719203 DOI: 10.1073/pnas.1908364116  1
2019 Huo L, Zhao X, Acedo JZ, Estrada P, Nair SK, van der Donk WA. Characterization of a dehydratase and methyltransferase in the biosynthesis of a ribosomally-synthesized and post-translationally modified peptide in Lachnospiraceae. Chembiochem : a European Journal of Chemical Biology. PMID 31532570 DOI: 10.1002/Cbic.201900483  1
2019 Bothwell IR, Cogan DP, Kim T, Reinhardt CJ, van der Donk WA, Nair SK. Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics. Proceedings of the National Academy of Sciences of the United States of America. PMID 31409709 DOI: 10.1073/pnas.1905240116  1
2019 Chekan JR, Ongpipattanakul C, Wright TR, Zhang B, Bollinger JM, Rajakovich LJ, Krebs C, Cicchillo RM, Nair SK. Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proceedings of the National Academy of Sciences of the United States of America. PMID 31209034 DOI: 10.1073/Pnas.1900711116  1
2019 Dong SH, Liu A, Mahanta N, Mitchell DA, Nair SK. Mechanistic Basis for Ribosomal Peptide Backbone Modifications. Acs Central Science. 5: 842-851. PMID 31139720 DOI: 10.1021/Acscentsci.9B00124  0.01
2019 Zukher I, Pavlov M, Tsibulskaya D, Kulikovsky A, Zyubko T, Bikmetov D, Serebryakova M, Nair SK, Ehrenberg M, Dubiley S, Severinov K. Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor. Mbio. 10. PMID 31040244 DOI: 10.1128/mBio.00768-19  0.01
2019 Dong SH, Kulikovsky A, Zukher I, Estrada P, Dubiley S, Severinov K, Nair SK. Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the -formyl of the peptide precursor. Chemical Science. 10: 2391-2395. PMID 30881667 DOI: 10.1039/c8sc03173h  0.01
2019 Petronikolou N, Ortega MA, Borisova SA, Nair SK, Metcalf WW. Molecular basis of Bacillus subtilis ATCC6633 self-resistance to the phosphono-oligopeptide antibiotic rhizocticin. Acs Chemical Biology. PMID 30830751 DOI: 10.1021/Acschembio.9B00030  1
2019 Nguyen K, DeSieno MA, Bae B, Johannes TW, Cobb RE, Zhao H, Nair SK. Characterization of the flavin monooxygenase involved in biosynthesis of the antimalarial FR-900098. Organic & Biomolecular Chemistry. PMID 30681110 DOI: 10.1039/C8Ob02840K  0.01
2019 Bobeica SC, Dong S, Huo L, Mazo N, McLaughlin MIH, Jiménez-Osés G, Nair SK, van der Donk WA. Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease. Elife. 8. PMID 30638446 DOI: 10.7554/Elife.42305  1
2018 Petronikolou N, Nair SK. Structural and Biochemical Studies of a Biocatalyst for the Enzymatic Production of Wax Esters. Acs Catalysis. 8: 6334-6344. PMID 31559109 DOI: 10.1021/acscatal.8b00787  0.01
2018 Ongpipattanakul C, Nair SK. Molecular Basis for Autocatalytic Backbone N-Methylation in RiPP Natural Product Biosynthesis. Acs Chemical Biology. 13: 2989-2999. PMID 30204409 DOI: 10.1021/acschembio.8b00668  0.01
2018 An L, Cogan DP, Navo CD, Jiménez-Osés G, Nair SK, van der Donk WA. Substrate-assisted enzymatic formation of lysinoalanine in duramycin. Nature Chemical Biology. PMID 30177849 DOI: 10.1038/s41589-018-0122-4  1
2018 Kapoor I, Nair SK. Structure-Guided Analyses of a Key Enzyme Involved in the Biosynthesis of an Antivitamin. Biochemistry. 57: 5282-5288. PMID 30125480 DOI: 10.1021/acs.biochem.8b00576  0.01
2018 O'Reilly MC, Dong SH, Rossi FM, Karlen KM, Kumar RS, Nair SK, Blackwell HE. Structural and Biochemical Studies of Non-native Agonists of the LasR Quorum-Sensing Receptor Reveal an L3 Loop "Out" Conformation for LasR. Cell Chemical Biology. PMID 30033130 DOI: 10.1016/J.Chembiol.2018.06.007  0.01
2018 Estrada P, Morita M, Hao Y, Schmidt EW, Nair S. A Single Amino Acid Switch Alters the Isoprene Donor Specificity in RiPP Prenyltransferases. Journal of the American Chemical Society. PMID 29924593 DOI: 10.1021/jacs.8b05187  1
2018 Cogan DP, Baraquet C, Harwood CS, Nair SK. Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism in Rhodopseudomonas palustris. The Journal of Biological Chemistry. PMID 29794028 DOI: 10.1074/Jbc.Ra118.003561  0.01
2018 Gu W, Dong SH, Sarkar S, Nair SK, Schmidt EW. The Biochemistry and Structural Biology of Cyanobactin Pathways: Enabling Combinatorial Biosynthesis. Methods in Enzymology. 604: 113-163. PMID 29779651 DOI: 10.1016/Bs.Mie.2018.03.002  1
2018 Morita M, Hao Y, Jokela J, Sardar D, Lin Z, Sivonen K, Nair SK, Schmidt EW. Posttranslational Tyrosine Geranylation in Cyanobactin Biosynthesis. Journal of the American Chemical Society. PMID 29701961 DOI: 10.1021/Jacs.8B03137  1
2018 Ongpipattanakul C, Nair SK. Biosynthetic Proteases That Catalyze the Macrocyclization of Ribosomally Synthesized Linear Peptides. Biochemistry. 57: 3201-3209. PMID 29553721 DOI: 10.1021/acs.biochem.8b00114  0.01
2018 Mahanta N, Liu A, Dong S, Nair SK, Mitchell DA. Enzymatic reconstitution of ribosomal peptide backbone thioamidation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507203 DOI: 10.1073/Pnas.1722324115  0.01
2018 Petronikolou N, Hollatz A, Schuler MA, Nair SK. Loganic Acid Methyltransferase: Insights into the specificity of methylation on an iridoid glycoside. Chembiochem : a European Journal of Chemical Biology. PMID 29399933 DOI: 10.1002/cbic.201700679  0.01
2017 Cogan DP, Hudson GA, Zhang Z, Pogorelov TV, van der Donk WA, Mitchell DA, Nair SK. Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158402 DOI: 10.1073/Pnas.1716035114  1
2017 Dong SH, Frane ND, Christensen QH, Greenberg EP, Nagarajan R, Nair SK. Molecular basis for the substrate specificity of quorum signal synthases. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784791 DOI: 10.1073/Pnas.1705400114  0.01
2017 Chekan JR, Estrada P, Covello PS, Nair SK. Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants. Proceedings of the National Academy of Sciences of the United States of America. PMID 28584123 DOI: 10.1073/pnas.1620499114  1
2017 Estrada P, Manandhar M, Dong SH, Deveryshetty J, Agarwal V, Cronan JE, Nair SK. The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes. Nature Chemical Biology. PMID 28414711 DOI: 10.1038/Nchembio.2359  1
2017 Sardar D, Hao Y, Lin Z, Morita M, Nair SK, Schmidt EW. Enzymatic N- and C-protection in cyanobactin RiPP natural products. Journal of the American Chemical Society. PMID 28195477 DOI: 10.1021/Jacs.6B12872  1
2017 Repka LM, Chekan JR, Nair SK, van der Donk WA. Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes. Chemical Reviews. PMID 28135077 DOI: 10.1021/acs.chemrev.6b00591  1
2016 Ortega MA, Cogan DP, Mukherjee S, Garg N, Li B, Thibodeaux GN, Maffioli S, Donadio S, Sosio M, Escano J, Smith L, Nair SK, van der Donk WA. Two flavoenzymes catalyze the post-translational generation of 5-chlorotryptophan and 2-aminovinyl-cysteine during NAI-107 biosynthesis. Acs Chemical Biology. PMID 28032983 DOI: 10.1021/Acschembio.6B01031  1
2016 Chekan JR, Koos JD, Zong C, Maksimov MO, Link AJ, Nair SK. Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates. Journal of the American Chemical Society. 138: 16452-16458. PMID 27998080 DOI: 10.1021/Jacs.6B10389  1
2016 Olivares P, Ulrich EC, Chekan JR, van der Donk WA, Nair SK. Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads. Acs Chemical Biology. PMID 27977135 DOI: 10.1021/acschembio.6b00939  1
2016 Hao Y, Pierce E, Roe D, Morita M, McIntosh JA, Agarwal V, Cheatham TE, Schmidt EW, Nair SK. Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872314 DOI: 10.1073/Pnas.1609869113  1
2016 Ortega MA, Hao Y, Walker MC, Donadio S, Sosio M, Nair SK, van der Donk WA. Structure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis. Cell Chemical Biology. PMID 26877024 DOI: 10.1016/J.Chembiol.2015.11.017  1
2016 Chekan JR, Cogan DP, Nair SK. Molecular Basis for Resistance Against Phosphonate Antibiotics and Herbicides. Medchemcomm. 7: 28-36. PMID 26811741 DOI: 10.1039/C5MD00351B  1
2015 Tang W, Dong SH, Repka LM, He C, Nair SK, van der Donk WA. Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage. Chemical Science. 6: 6270-6279. PMID 30090246 DOI: 10.1039/C5Sc02329G  1
2015 Petronikolou N, Nair SK. Biochemical Studies of Mycobacterial Fatty Acid Methyltransferase: A Catalyst for the Enzymatic Production of Biodiesel. Chemistry & Biology. PMID 26526103 DOI: 10.1016/j.chembiol.2015.09.011  1
2015 Li Z, Nair SK. Structural Basis for Specificity and Flexibility in a Plant 4-Coumarate:CoA Ligase. Structure (London, England : 1993). PMID 26412334 DOI: 10.1016/j.str.2015.08.012  1
2015 Dong SH, Tang W, Lukk T, Yu Y, Nair SK, van der Donk WA. The enterrococcal cytolysin synthetase has an unanticipated lipid kinase fold. Elife. 4. PMID 26226635 DOI: 10.7554/Elife.07607  1
2015 Peck SC, Chekan JR, Ulrich EC, Nair SK, van der Donk WA. A common late-stage intermediate in catalysis by 2-hydroxyethyl-phosphonate dioxygenase and methylphosphonate synthase. Journal of the American Chemical Society. 137: 3217-20. PMID 25699631 DOI: 10.1021/Jacs.5B00282  1
2015 Hao Y, Blair PM, Sharma A, Mitchell DA, Nair SK. Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. Acs Chemical Biology. 10: 1209-16. PMID 25635336 DOI: 10.1021/Cb501042A  1
2015 Cobb RE, Bae B, Li Z, DeSieno MA, Nair SK, Zhao H. Structure-guided design and biosynthesis of a novel FR-900098 analogue as a potent Plasmodium falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr) inhibitor. Chemical Communications (Cambridge, England). 51: 2526-8. PMID 25567100 DOI: 10.1039/C4Cc09181G  1
2015 Ortega MA, Hao Y, Zhang Q, Walker MC, van der Donk WA, Nair SK. Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB. Nature. 517: 509-12. PMID 25363770 DOI: 10.1038/Nature13888  1
2014 van der Donk WA, Nair SK. Structure and mechanism of lanthipeptide biosynthetic enzymes. Current Opinion in Structural Biology. 29: 58-66. PMID 25460269 DOI: 10.1016/j.sbi.2014.09.006  1
2014 Chekan JR, Kwon IH, Agarwal V, Dodd D, Revindran V, Mackie RI, Cann I, Nair SK. Structural and biochemical basis for mannan utilization by Caldanaerobius polysaccharolyticus strain ATCC BAA-17. The Journal of Biological Chemistry. 289: 34965-77. PMID 25342756 DOI: 10.1074/Jbc.M114.579904  1
2014 Dunbar KL, Chekan JR, Cox CL, Burkhart BJ, Nair SK, Mitchell DA. Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis. Nature Chemical Biology. 10: 823-9. PMID 25129028 DOI: 10.1038/Nchembio.1608  1
2014 Majumdar S, Lukk T, Solbiati JO, Bauer S, Nair SK, Cronan JE, Gerlt JA. Roles of small laccases from Streptomyces in lignin degradation. Biochemistry. 53: 4047-58. PMID 24870309 DOI: 10.1021/Bi500285T  0.01
2014 Ortega MA, Velásquez JE, Garg N, Zhang Q, Joyce RE, Nair SK, van der Donk WA. Substrate specificity of the lanthipeptide peptidase ElxP and the oxidoreductase ElxO. Acs Chemical Biology. 9: 1718-25. PMID 24866416 DOI: 10.1021/Cb5002526  1
2014 Hung JE, Fogle EJ, Garg N, Chekan JR, Nair SK, van der Donk WA. Chemical rescue and inhibition studies to determine the role of Arg301 in phosphite dehydrogenase. Plos One. 9: e87134. PMID 24498026 DOI: 10.1371/Journal.Pone.0087134  1
2014 Park D, Jagtap S, Nair SK. Structure of a PL17 family alginate lyase demonstrates functional similarities among exotype depolymerases. The Journal of Biological Chemistry. 289: 8645-55. PMID 24478312 DOI: 10.1074/jbc.M113.531111  1
2014 Agarwal V, Peck SC, Chen JH, Borisova SA, Chekan JR, van der Donk WA, Nair SK. Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation. Chemistry & Biology. 21: 125-35. PMID 24361046 DOI: 10.1016/J.Chembiol.2013.11.006  1
2013 Gonzalez-Gutierrez G, Cuello LG, Nair SK, Grosman C. Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. 110: 18716-21. PMID 24167270 DOI: 10.1073/Pnas.1313156110  1
2013 Lee J, Hao Y, Blair PM, Melby JO, Agarwal V, Burkhart BJ, Nair SK, Mitchell DA. Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 12954-9. PMID 23878226 DOI: 10.1073/Pnas.1306101110  1
2013 Perry SL, Guha S, Pawate AS, Bhaskarla A, Agarwal V, Nair SK, Kenis PJ. A microfluidic approach for protein structure determination at room temperature via on-chip anomalous diffraction. Lab On a Chip. 13: 3183-7. PMID 23828485 DOI: 10.1039/C3Lc50276G  1
2013 Kelley SL, Lukk T, Nair SK, Tapping RI. The crystal structure of human soluble CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket. Journal of Immunology (Baltimore, Md. : 1950). 190: 1304-11. PMID 23264655 DOI: 10.4049/Jimmunol.1202446  1
2013 Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... Nair SK, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/C2Np20085F  1
2012 Agarwal V, Pierce E, McIntosh J, Schmidt EW, Nair SK. Structures of cyanobactin maturation enzymes define a family of transamidating proteases. Chemistry & Biology. 19: 1411-22. PMID 23177196 DOI: 10.1016/J.Chembiol.2012.09.012  1
2012 Agarwal V, Lin S, Lukk T, Nair SK, Cronan JE. Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 17406-11. PMID 23045647 DOI: 10.1073/Pnas.1207028109  1
2012 Han Y, Agarwal V, Dodd D, Kim J, Bae B, Mackie RI, Nair SK, Cann IK. Biochemical and structural insights into xylan utilization by the thermophilic bacterium Caldanaerobius polysaccharolyticus. The Journal of Biological Chemistry. 287: 34946-60. PMID 22918832 DOI: 10.1074/Jbc.M112.391532  1
2012 Li Z, Nair SK. Quorum sensing: how bacteria can coordinate activity and synchronize their response to external signals? Protein Science : a Publication of the Protein Society. 21: 1403-17. PMID 22825856 DOI: 10.1002/pro.2132  1
2012 Li Z, Chen JH, Hao Y, Nair SK. Structures of the PelD cyclic diguanylate effector involved in pellicle formation in Pseudomonas aeruginosa PAO1. The Journal of Biological Chemistry. 287: 30191-204. PMID 22810222 DOI: 10.1074/jbc.M112.378273  1
2012 Liu YL, Guerra F, Wang K, Wang W, Li J, Huang C, Zhu W, Houlihan K, Li Z, Zhang Y, Nair SK, Oldfield E. Structure, function and inhibition of the two- and three-domain 4Fe-4S IspG proteins. Proceedings of the National Academy of Sciences of the United States of America. 109: 8558-63. PMID 22586085 DOI: 10.1073/Pnas.1121107109  1
2012 Zou Y, Zhang H, Brunzelle JS, Johannes TW, Woodyer R, Hung JE, Nair N, Van Der Donk WA, Zhao H, Nair SK. Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration Biochemistry. 51: 4263-4270. PMID 22564171 DOI: 10.1021/Bi2016926  1
2012 Gonzalez-Gutierrez G, Lukk T, Agarwal V, Papke D, Nair SK, Grosman C. Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proceedings of the National Academy of Sciences of the United States of America. 109: 6331-6. PMID 22474383 DOI: 10.1073/Pnas.1119268109  1
2012 Garg N, Tang W, Goto Y, Nair SK, Van Der Donk WA. Lantibiotics from Geobacillus thermodenitrificans Proceedings of the National Academy of Sciences of the United States of America. 109: 5241-5246. PMID 22431611 DOI: 10.1073/Pnas.1116815109  1
2012 Lukk T, Sakai A, Kalyanaraman C, Brown SD, Imker HJ, Song L, Fedorov AA, Fedorov EV, Toro R, Hillerich B, Seidel R, Patskovsky Y, Vetting MW, Nair SK, Babbitt PC, et al. Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proceedings of the National Academy of Sciences of the United States of America. 109: 4122-7. PMID 22392983 DOI: 10.1073/Pnas.1112081109  1
2012 Agarwal V, Tikhonov A, Metlitskaya A, Severinov K, Nair SK. Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7. Proceedings of the National Academy of Sciences of the United States of America. 109: 4425-30. PMID 22388748 DOI: 10.1073/pnas.1114224109  1
2012 Severinov K, Nair SK. Microcin C: biosynthesis and mechanisms of bacterial resistance. Future Microbiology. 7: 281-9. PMID 22324995 DOI: 10.2217/fmb.11.148  1
2011 Agarwal V, Borisova SA, Metcalf WW, van der Donk WA, Nair SK. Structural and mechanistic insights into C-P bond hydrolysis by phosphonoacetate hydrolase. Chemistry & Biology. 18: 1230-40. PMID 22035792 DOI: 10.1016/J.Chembiol.2011.07.019  1
2011 Bae B, Cobb RE, DeSieno MA, Zhao H, Nair SK. New N-acetyltransferase fold in the structure and mechanism of the phosphonate biosynthetic enzyme FrbF. The Journal of Biological Chemistry. 286: 36132-41. PMID 21865168 DOI: 10.1074/Jbc.M111.263533  1
2011 McIntosh JA, Donia MS, Nair SK, Schmidt EW. Enzymatic basis of ribosomal peptide prenylation in cyanobacteria. Journal of the American Chemical Society. 133: 13698-705. PMID 21766822 DOI: 10.1021/Ja205458H  1
2011 Peck SC, Cooke HA, Cicchillo RM, Malova P, Hammerschmidt F, Nair SK, van der Donk WA. Mechanism and substrate recognition of 2-hydroxyethylphosphonate dioxygenase. Biochemistry. 50: 6598-605. PMID 21711001 DOI: 10.1021/Bi200804R  1
2011 Agarwal V, Metlitskaya A, Severinov K, Nair SK. Structural basis for microcin C7 inactivation by the MccE acetyltransferase. The Journal of Biological Chemistry. 286: 21295-303. PMID 21507941 DOI: 10.1074/jbc.M111.226282  1
2011 Li Z, Rupasinghe SG, Schuler MA, Nair SK. Crystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesis. Proteins. 79: 1728-38. PMID 21445994 DOI: 10.1002/Prot.22996  1
2011 Yoshida S, Park DS, Bae B, Mackie R, Cann IK, Nair SK. Structural and functional analyses of a glycoside hydrolase family 5 enzyme with an unexpected β-fucosidase activity. Biochemistry. 50: 3369-75. PMID 21410228 DOI: 10.1021/Bi200222U  1
2011 Nair SK, Van Der Donk WA. Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin Archives of Biochemistry and Biophysics. 505: 13-21. PMID 20854789 DOI: 10.1016/j.abb.2010.09.012  1
2010 McIntosh JA, Robertson CR, Agarwal V, Nair SK, Bulaj GW, Schmidt EW. Circular logic: nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst. Journal of the American Chemical Society. 132: 15499-501. PMID 20961047 DOI: 10.1021/Ja1067806  1
2010 Lee JH, Bae B, Kuemin M, Circello BT, Metcalf WW, Nair SK, Van Der Donk WA. Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis Proceedings of the National Academy of Sciences of the United States of America. 107: 17557-17562. PMID 20876132 DOI: 10.1073/Pnas.1006848107  1
2010 Su X, Agarwal V, Dodd D, Bae B, Mackie RI, Nair SK, Cann IK. Mutational insights into the roles of amino acid residues in ligand binding for two closely related family 16 carbohydrate binding modules. The Journal of Biological Chemistry. 285: 34665-76. PMID 20739280 DOI: 10.1074/Jbc.M110.168302  1
2010 Bae B, Sullivan RP, Zhao H, Nair SK. Structure and engineering of L-arabinitol 4-dehydrogenase from Neurospora crassa. Journal of Molecular Biology. 402: 230-40. PMID 20655316 DOI: 10.1016/J.Jmb.2010.07.033  1
2010 Lin LJ, Yoshinaga A, Lin Y, Guzman C, Chen YH, Mei S, Lagunas AM, Koike S, Iwai S, Spies MA, Nair SK, Mackie RI, Ishino Y, Cann IK. Molecular analyses of an unusual translesion DNA polymerase from Methanosarcina acetivorans C2A. Journal of Molecular Biology. 397: 13-30. PMID 20080107 DOI: 10.1016/J.Jmb.2010.01.007  1
2010 Lhee S, Kolling DR, Nair SK, Dikanov SA, Crofts AR. Modifications of protein environment of the [2Fe-2S] cluster of the bc1 complex: effects on the biophysical properties of the rieske iron-sulfur protein and on the kinetics of the complex. The Journal of Biological Chemistry. 285: 9233-48. PMID 20023300 DOI: 10.1074/Jbc.M109.043505  1
2009 Zou Y, Nair SK. Molecular Basis for the Recognition of Structurally Distinct Autoinducer Mimics by the Pseudomonas aeruginosa LasR Quorum-Sensing Signaling Receptor Chemistry and Biology. 16: 961-970. PMID 19778724 DOI: 10.1016/j.chembiol.2009.09.001  1
2009 Cicchillo RM, Zhang H, Blodgett JAV, Whitteck JT, Li G, Nair SK, Van Der Donk WA, Metcalf WW. An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis Nature. 459: 871-874. PMID 19516340 DOI: 10.1038/Nature07972  1
2009 Bae B, Chen YH, Costa A, Onesti S, Brunzelle JS, Lin Y, Cann IK, Nair SK. Insights into the architecture of the replicative helicase from the structure of an archaeal MCM homolog. Structure (London, England : 1993). 17: 211-22. PMID 19217392 DOI: 10.1016/J.Str.2008.11.010  1
2008 Rubin-Pitel SB, Zhang H, Vu T, Brunzelle JS, Zhao H, Nair SK. Distinct structural elements dictate the specificity of the type III pentaketide synthase from Neurospora crassa. Chemistry & Biology. 15: 1079-90. PMID 18940668 DOI: 10.1016/J.Chembiol.2008.08.011  1
2008 Costa A, van Duinen G, Medagli B, Chong J, Sakakibara N, Kelman Z, Nair SK, Patwardhan A, Onesti S. Cryo-electron microscopy reveals a novel DNA-binding site on the MCM helicase. The Embo Journal. 27: 2250-8. PMID 18650940 DOI: 10.1038/Emboj.2008.135  1
2008 Zou Y, Brunzelle JS, Nair SK. Crystal Structures of Lipoglycopeptide Antibiotic Deacetylases: Implications for the Biosynthesis of A40926 and Teicoplanin Chemistry and Biology. 15: 533-545. PMID 18559264 DOI: 10.1016/j.chembiol.2008.05.009  1
2008 Choi YS, Zhang H, Brunzelle JS, Nair SK, Zhao H. In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 6858-63. PMID 18458342 DOI: 10.1073/Pnas.0712073105  1
2008 Bae B, Ohene-Adjei S, Kocherginskaya S, Mackie RI, Spies MA, Cann IK, Nair SK. Molecular basis for the selectivity and specificity of ligand recognition by the family 16 carbohydrate-binding modules from Thermoanaerobacterium polysaccharolyticum ManA. The Journal of Biological Chemistry. 283: 12415-25. PMID 18025086 DOI: 10.1074/Jbc.M706513200  1
2007 Zou Y, Li C, Brunzelle JS, Nair SK. Molecular basis for substrate selectivity and specificity by an LPS biosynthetic enzyme. Biochemistry. 46: 4294-304. PMID 17371001 DOI: 10.1021/bi061056u  0.01
2007 Kemp M, Bae B, Yu JP, Ghosh M, Leffak M, Nair SK. Structure and function of the c-myc DNA-unwinding element-binding protein DUE-B. The Journal of Biological Chemistry. 282: 10441-8. PMID 17264083 DOI: 10.1074/Jbc.M609632200  0.01
2007 Kolling DJ, Brunzelle JS, Lhee S, Crofts AR, Nair SK. Atomic resolution structures of rieske iron-sulfur protein: role of hydrogen bonds in tuning the redox potential of iron-sulfur clusters. Structure (London, England : 1993). 15: 29-38. PMID 17223530 DOI: 10.1016/J.Str.2006.11.012  1
2006 Lin Y, Guzman CE, McKinney MC, Nair SK, Ha T, Cann IK. Methanosarcina acetivorans flap endonuclease 1 activity is inhibited by a cognate single-stranded-DNA-binding protein. Journal of Bacteriology. 188: 6153-67. PMID 16923882 DOI: 10.1128/Jb.00045-06  1
2006 Dikanov SA, Kolling DR, Endeward B, Samoilova RI, Prisner TF, Nair SK, Crofts AR. Identification of hydrogen bonds to the Rieske cluster through the weakly coupled nitrogens detected by electron spin echo envelope modulation spectroscopy. The Journal of Biological Chemistry. 281: 27416-25. PMID 16854984 DOI: 10.1074/Jbc.M604103200  1
2006 Lasker MV, Nair SK. Intracellular TLR signaling: a structural perspective on human disease. Journal of Immunology (Baltimore, Md. : 1950). 177: 11-6. PMID 16785490 DOI: 10.4049/jimmunol.177.1.11  0.01
2006 Lasker MV, Kuruvilla SM, Gajjar MM, Kapoor A, Nair SK. Metal ion-mediated reduction in surface entropy improves diffraction quality of crystals of the IRAK-4 death domain. Journal of Biomolecular Techniques : Jbt. 17: 114-21. PMID 16741238  1
2006 Li B, Yu JP, Brunzelle JS, Moll GN, van der Donk WA, Nair SK. Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis. Science (New York, N.Y.). 311: 1464-7. PMID 16527981 DOI: 10.1126/Science.1121422  1
2005 Lasker MV, Gajjar MM, Nair SK. Cutting edge: molecular structure of the IL-1R-associated kinase-4 death domain and its implications for TLR signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 4175-9. PMID 16177054  1
2003 Nair SK, Burley SK. X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors. Cell. 112: 193-205. PMID 12553908 DOI: 10.1016/S0092-8674(02)01284-9  0.01
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