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Victor Esteban Marquez - Publications

Affiliations: 
National Cancer Institute, NIH, Bethesda, Bethesda, MD, United States 
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Garcia LC, Donadío LG, Mann E, Kolusheva S, Kedei N, Lewin NE, Hill CS, Kelsey JS, Yang J, Esch TE, Santos M, Peach ML, Kelley JA, Blumberg PM, Jelinek R, ... Marquez VE, et al. Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP. Bioorganic & Medicinal Chemistry. 22: 3123-40. PMID 24794745 DOI: 10.1016/J.Bmc.2014.04.024  0.731
2013 Kirby KA, Michailidis E, Fetterly TL, Steinbach MA, Singh K, Marchand B, Leslie MD, Hagedorn AN, Kodama EN, Marquez VE, Hughes SH, Mitsuya H, Parniak MA, Sarafianos SG. Effects of substitutions at the 4' and 2 positions on the bioactivity of 4'-ethynyl-2-fluoro-2'-deoxyadenosine. Antimicrobial Agents and Chemotherapy. 57: 6254-64. PMID 24100493 DOI: 10.1128/Aac.01703-13  0.345
2012 Ludek OR, Marquez VE. Synthesis of conformationally North-locked pyrimidine nucleosides built on an oxabicyclo[3.1.0]hexane scaffold. The Journal of Organic Chemistry. 77: 815-24. PMID 22026578 DOI: 10.1021/jo201716c  0.376
2011 Gal N, Kolusheva S, Kedei N, Telek A, Naeem TA, Lewin NE, Lim L, Mannan P, Garfield SH, El Kazzouli S, Sigano DM, Marquez VE, Blumberg PM, Jelinek R. N-methyl-substituted fluorescent DAG-indololactone isomers exhibit dramatic differences in membrane interactions and biological activity. Chembiochem : a European Journal of Chemical Biology. 12: 2331-40. PMID 23106081 DOI: 10.1002/Cbic.201100246  0.344
2011 Gal N, Kolusheva S, Kedei N, Telek A, Naeem TA, Lewin NE, Lim L, Mannan P, Garfield SH, El Kazzouli S, Sigano DM, Marquez VE, Blumberg PM, Jelinek R. N-methyl-substituted fluorescent DAG-indololactone isomers exhibit dramatic differences in membrane interactions and biological activity. Chembiochem : a European Journal of Chemical Biology. 12: 2331-40. PMID 23106081 DOI: 10.1002/Cbic.201100246  0.344
2010 Raifman O, Kolusheva S, El Kazzouli S, Sigano DM, Kedei N, Lewin NE, Lopez-Nicolas R, Ortiz-Espin A, Gomez-Fernandez JC, Blumberg PM, Marquez VE, Corbalan-Garcia S, Jelinek R. Membrane-surface anchoring of charged diacylglycerol-lactones correlates with biological activities. Chembiochem : a European Journal of Chemical Biology. 11: 2003-9. PMID 20715268 DOI: 10.1002/Cbic.201000343  0.356
2010 Raifman O, Kolusheva S, Comin MJ, Kedei N, Lewin NE, Blumberg PM, Marquez VE, Jelinek R. Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities. The Febs Journal. 277: 233-43. PMID 19961537 DOI: 10.1111/J.1742-4658.2009.07477.X  0.678
2009 Comin MJ, Czifra G, Kedei N, Telek A, Lewin NE, Kolusheva S, Velasquez JF, Kobylarz R, Jelinek R, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths. Journal of Medicinal Chemistry. 52: 3274-83. PMID 19379015 DOI: 10.1021/Jm900186M  0.729
2008 Philosof-Mazor L, Volinsky R, Comin MJ, Lewin NE, Kedei N, Blumberg PM, Marquez VE, Jelinek R. Self-assembly and lipid interactions of diacylglycerol lactone derivatives studied at the air/water interface. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 11043-52. PMID 18788772 DOI: 10.1021/La802204N  0.707
2008 Ludek OR, Schroeder GK, Wolfenden R, Marquez VE. Synthesis of conformationally locked carbocyclic 1,3-diazepinone nucleosides as inhibitors of cytidine deaminase. Nucleic Acids Symposium Series (2004). 659-60. PMID 18776552 DOI: 10.1093/nass/nrn333  0.335
2008 El Kazzouli S, Lewin NE, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol. 30. An investigation of diacylglycerol-lactones containing heteroaryl groups reveals compounds with high selectivity for Ras guanyl nucleotide-releasing proteins. Journal of Medicinal Chemistry. 51: 5371-86. PMID 18707088 DOI: 10.1021/Jm800380B  0.329
2008 Comin MJ, Vu BC, Boyer PL, Liao C, Hughes SH, Marquez VE. D-(+)-iso-methanocarbathymidine: a high-affinity substrate for herpes simplex virus 1 thymidine kinase. Chemmedchem. 3: 1129-34. PMID 18399509 DOI: 10.1002/cmdc.200800027  0.712
2007 Marquez VE, Comin MJ. Rearranging the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve binding recognition by kinases. Nucleosides, Nucleotides & Nucleic Acids. 26: 585-8. PMID 18066860 DOI: 10.1080/15257770701490175  0.692
2007 Comin MJ, Agbaria R, Ben-Kasus T, Huleihel M, Liao C, Sun G, Nicklaus MC, Deschamps JR, Parrish DA, Marquez VE. Sculpting the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve recognition by herpes thymidine kinase. Journal of the American Chemical Society. 129: 6216-22. PMID 17451242 DOI: 10.1021/ja0688732  0.736
2007 Malolanarasimhan K, Kedei N, Sigano DM, Kelley JA, Lai CC, Lewin NE, Surawski RJ, Pavlyukovets VA, Garfield SH, Wincovitch S, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups. Journal of Medicinal Chemistry. 50: 962-78. PMID 17284021 DOI: 10.1021/Jm061289J  0.317
2006 Kang JH, Benzaria S, Sigano DM, Lewin NE, Pu Y, Peach ML, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol. 26. Exploring the chemical space surrounding the C1 domain of protein kinase C with DAG-lactones containing aryl groups at the sn-1 and sn-2 positions. Journal of Medicinal Chemistry. 49: 3185-203. PMID 16722637 DOI: 10.1021/Jm060011O  0.337
2006 Comin MJ, Parrish DA, Deschamps JR, Marquez VE. Synthesis of bicyclo[3.1.0]hexanes functionalized at the tip of the cyclopropane ring. Application to the synthesis of carbocyclic nucleosides. Organic Letters. 8: 705-8. PMID 16468747 DOI: 10.1021/ol052886n  0.706
2005 Marquez VE, Choi Y, Comin MJ, Russ P, George C, Huleihel M, Ben-Kasus T, Agbaria R. Understanding how the herpes thymidine kinase orchestrates optimal sugar and nucleobase conformations to accommodate its substrate at the active site: a chemical approach. Journal of the American Chemical Society. 127: 15145-50. PMID 16248655 DOI: 10.1021/Ja053789S  0.685
2004 Tamamura H, Sigano DM, Lewin NE, Peach ML, Nicklaus MC, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C). Journal of Medicinal Chemistry. 47: 4858-64. PMID 15369389 DOI: 10.1021/Jm049723+  0.308
2004 Kang JH, Kim SY, Lee J, Marquez VE, Lewin NE, Pearce LV, Blumberg PM. Macrocyclic diacylglycerol-bis-lactones as conformationally constrained analogues of diacylglycerol-lactones. Interactions with protein kinase C. Journal of Medicinal Chemistry. 47: 4000-7. PMID 15267238 DOI: 10.1021/Jm0497747  0.307
2004 Marquez VE, Blumberg PM. Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C). Accounts of Chemical Research. 36: 434-43. PMID 12809530 DOI: 10.1021/Ar020124B  0.314
2003 Choi Y, Sun G, George C, Nicklaus MC, Kelley JA, Marquez VE. Synthesis and conformational analysis of a locked analogue of carbovir built on a bicyclo[3.1.0]hex-2-enyl template. Nucleosides, Nucleotides & Nucleic Acids. 22: 2077-91. PMID 14714758 DOI: 10.1081/Ncn-120026631  0.309
2003 Russ P, Schelling P, Scapozza L, Folkers G, Clercq ED, Marquez VE. Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine. Journal of Medicinal Chemistry. 46: 5045-54. PMID 14584954 DOI: 10.1021/Jm030241S  0.315
2003 Kim HS, Ohno M, Xu B, Kim HO, Choi Y, Ji XD, Maddileti S, Marquez VE, Harden TK, Jacobson KA. 2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists. Journal of Medicinal Chemistry. 46: 4974-87. PMID 14584948 DOI: 10.1021/Jm030127+  0.301
2003 Choi Y, George C, Comin MJ, Barchi JJ, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Journal of Medicinal Chemistry. 46: 3292-9. PMID 12852759 DOI: 10.1021/Jm030116G  0.692
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