J. Manuel Perez - Related publications

Affiliations: 
2003-2005 MGH-Harvard Medical School 
 2005-2015 University of Central Florida, Orlando, FL, United States 
 2015- Cedar Sinai Medical Center, Los Angeles 
Area:
Nanomedicine, biomedical science
Website:
https://www.cedars-sinai.edu/research/labs/perez.html
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Yim SY, Lee JS. An Overview of the Genomic Characterization of Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma. 8: 1077-1088. PMID 34522690 DOI: 10.2147/JHC.S270533   
2021 Talwelkar SS, Mäyränpää MI, Søraas L, Potdar S, Bao J, Hemmes A, Linnavirta N, Lømo J, Räsänen J, Knuuttila A, Wennerberg K, Verschuren EW. Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments. Cell Reports. Medicine. 2: 100373. PMID 34467250 DOI: 10.1016/j.xcrm.2021.100373   
2021 Kumar LA, Pattnaik G, Satapathy BS, Swapna S, Mohanty D. Targeting to Brain Tumor: Nanocarrier-Based Drug Delivery Platforms, Opportunities, and Challenges. Journal of Pharmacy & Bioallied Sciences. 13: 172-177. PMID 34349476 DOI: 10.4103/jpbs.JPBS_239_20   
2021 Pan Y, Song X, Wang Y, Wei J. Firing up the Tumor Microenvironment with Nanoparticle-Based Therapies. Pharmaceutics. 13. PMID 34575414 DOI: 10.3390/pharmaceutics13091338   
2021 Gao R, Zhao S, Aishanjiang K, Cai H, Wei T, Zhang Y, Liu Z, Zhou J, Han B, Wang J, Ding H, Liu Y, Xu X, Yu Z, Gu J. Deep learning for differential diagnosis of malignant hepatic tumors based on multi-phase contrast-enhanced CT and clinical data. Journal of Hematology & Oncology. 14: 154. PMID 34565412 DOI: 10.1186/s13045-021-01167-2   
2021 Salari N, Mansouri K, Valipour E, Abam F, Jaymand M, Rasoulpoor S, Dokaneheifard S, Mohammadi M. Hyaluronic acid-based drug nanocarriers as a novel drug delivery system for cancer chemotherapy: A systematic review. Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences. PMID 34499323 DOI: 10.1007/s40199-021-00416-6   
2021 Aryal M, Porter T. Emerging Therapeutic Strategies for Brain Tumors. Neuromolecular Medicine. PMID 34406634 DOI: 10.1007/s12017-021-08681-z   
2021 Yuan C, Zhao X, Wangmo D, Alshareef D, Gates TJ, Subramanian S. Tumor models to assess immune response and tumor-microbiome interactions in colorectal cancer. Pharmacology & Therapeutics. 107981. PMID 34480964 DOI: 10.1016/j.pharmthera.2021.107981   
2021 Liu J, Tian Z, Liu T, Wen D, Ma Z, Liu Y, Zhu J. CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration. Cell Cycle (Georgetown, Tex.). 1-14. PMID 34412565 DOI: 10.1080/15384101.2021.1963553   
2021 Edwards K, Yao S, Pisano S, Feltracco V, Brusehafer K, Samanta S, Oommen OP, Gazze SA, Paravati R, Maddison H, Li C, Gonzalez D, Conlan RS, Francis L. Hyaluronic Acid-Functionalized Nanomicelles Enhance SAHA Efficacy in 3D Endometrial Cancer Models. Cancers. 13. PMID 34439185 DOI: 10.3390/cancers13164032   
2021 Zou J, Yang X, Duan J, Wang J, Yang Z, Luo D, Liu L, Chen J, Nie J. A Case Report of Targeted Therapy with Anlotinib in a Patient with Advanced Breast Metaplastic Carcinoma. Oncotargets and Therapy. 14: 4599-4607. PMID 34475766 DOI: 10.2147/OTT.S318645   
2021 Gupta AR, Woodard GA, Jablons DM, Mann MJ, Kratz JR. Improved outcomes and staging in non-small-cell lung cancer guided by a molecular assay. Future Oncology (London, England). PMID 34435876 DOI: 10.2217/fon-2021-0517   
2021 Lu T, Wei L, Huang X, Li Y, Li G, Qin Q, Pan M, Tang B, Pan X, Wei M, Nong Z, Meng F, Li X. A potentially valuable nano graphene oxide/USPIO tumor diagnosis and treatment system. Materials Science & Engineering. C, Materials For Biological Applications. 128: 112293. PMID 34474844 DOI: 10.1016/j.msec.2021.112293   
2021 Xia W, Tao Z, Zhu B, Zhang W, Liu C, Chen S, Song M. Targeted Delivery of Drugs and Genes Using Polymer Nanocarriers for Cancer Therapy. International Journal of Molecular Sciences. 22. PMID 34502028 DOI: 10.3390/ijms22179118   
2021 Zhang Y, Li Y, Huang S, Zhang H, Lin Q, Gong T, Sun X, Zhang Z, Zhang L. Enhanced anti-metastatic therapy with down-regulation of heparinase expression by ROS-responsive micellar nanoparticles. Nanoscale. PMID 34477185 DOI: 10.1039/d1nr02964a   
2021 Haque MR, Rempert TH, Al-Hilal TA, Wang C, Bhushan A, Bishehsari F. Organ-Chip Models: Opportunities for Precision Medicine in Pancreatic Cancer. Cancers. 13. PMID 34503294 DOI: 10.3390/cancers13174487   
2021 Pachva MC, Lai H, Jia A, Rouleau M, Sorensen PH. Extracellular Vesicles in Reprogramming of the Ewing Sarcoma Tumor Microenvironment. Frontiers in Cell and Developmental Biology. 9: 726205. PMID 34604225 DOI: 10.3389/fcell.2021.726205   
2021 Gao Y, Wang J, Han H, Xiao H, Jin WK, Wang S, Shao S, Wang Z, Yang W, Wang L, Weng L. A nanoparticle-containing polycaprolactone implant for combating post-resection breast cancer recurrence. Nanoscale. 13: 14417-14425. PMID 34473184 DOI: 10.1039/d1nr04125h   
2021 Di Capua D, Bracken-Clarke D, Ronan K, Baird AM, Finn S. The Liquid Biopsy for Lung Cancer: State of the Art, Limitations and Future Developments. Cancers. 13. PMID 34439082 DOI: 10.3390/cancers13163923   
2021 Eickstaedt JB, Fancher W, Havighurst T, Xu YG. Lack of documentation of lymph node examination in patients with squamous cell carcinoma of the lower lip. Archives of Dermatological Research. PMID 34562138 DOI: 10.1007/s00403-021-02281-4   
2021 Zhong Y, Bejjanki NK, Miao X, Weng H, Li Q, Zhang J, Liu T, Vannam R, Xie M. Synthesis and Photothermal Effects of Intracellular Aggregating Nanodrugs Targeting Nasopharyngeal Carcinoma. Frontiers in Bioengineering and Biotechnology. 9: 730925. PMID 34604188 DOI: 10.3389/fbioe.2021.730925   
2021 Chang Y, Wang Y, Li B, Lu X, Wang R, Li H, Yan B, Gu A, Wang W, Huang A, Wu S, Li R. Whole-Exome Sequencing on Circulating Tumor Cells Explores Platinum-Drug Resistance Mutations in Advanced Non-small Cell Lung Cancer. Frontiers in Genetics. 12: 722078. PMID 34616428 DOI: 10.3389/fgene.2021.722078   
2021 Poonan P, Agoni C, Ibrahim MAA, Soliman MES. Glioma-Targeted Therapeutics: Computer-Aided Drug Design Prospective. The Protein Journal. 40: 601-655. PMID 34590194 DOI: 10.1007/s10930-021-10021-w   
2021 Mentink JF, Paats MS, Dumoulin DW, Cornelissen R, Elbers JBW, Maat APWM, von der Thüsen JH, Dingemans AC. Defining oligometastatic non-small cell lung cancer: concept versus biology, a literature review. Translational Lung Cancer Research. 10: 3329-3338. PMID 34430370 DOI: 10.21037/tlcr-21-265   
2021 Castro J, Tornillo G, Ceada G, Ramos-Neble B, Bravo M, Ribó M, Vilanova M, Smalley MJ, Benito A. A Nuclear-Directed Ribonuclease Variant Targets Cancer Stem Cells and Inhibits Migration and Invasion of Breast Cancer Cells. Cancers. 13. PMID 34503160 DOI: 10.3390/cancers13174350   
2021 Guo R, Zhang D, Zhang C, Yang Y, Liu H, Yang Y, Lin J. Immunotoxin IHP25-BT with low immunogenicity and off-target toxicity inhibits the growth and metastasis of trastuzumab-resistant tumor cells. International Journal of Pharmaceutics. 121081. PMID 34506924 DOI: 10.1016/j.ijpharm.2021.121081   
2021 Nakamura Y, Fujisawa T, Taniguchi H, Bando H, Okamoto W, Tsuchihara K, Yoshino T, Ohtsu A. SCRUM-Japan GI-SCREEN and MONSTAR-SCREEN: Path to the realization of biomarker-guided precision oncology in advanced solid tumors. Cancer Science. PMID 34510657 DOI: 10.1111/cas.15132   
2021 Lawal B, Tseng SH, Olugbodi JO, Iamsaard S, Ilesanmi OB, Mahmoud MH, Ahmed SH, Batiha GE, Wu ATH. Pan-Cancer Analysis of Immune Complement Signature C3/C5/C3AR1/C5AR1 in Association with Tumor Immune Evasion and Therapy Resistance. Cancers. 13. PMID 34439277 DOI: 10.3390/cancers13164124   
2021 He F, Xia Y, Ling X. Diagnosis and Individualized Treatment of Three Primary Malignant Tumors: A Case Report. Breast Cancer (Dove Medical Press). 13: 519-527. PMID 34526817 DOI: 10.2147/BCTT.S321390   
2021 Scott AJ, Lyssiotis CA, Wahl DR. Clinical Targeting of Altered Metabolism in High-Grade Glioma. Cancer Journal (Sudbury, Mass.). 27: 386-394. PMID 34570453 DOI: 10.1097/PPO.0000000000000550   
2021 Anjum S, Hashim M, Malik SA, Khan M, Lorenzo JM, Abbasi BH, Hano C. Recent Advances in Zinc Oxide Nanoparticles (ZnO NPs) for Cancer Diagnosis, Target Drug Delivery, and Treatment. Cancers. 13. PMID 34572797 DOI: 10.3390/cancers13184570   
2021 Saif MW, Rajagopal S, Caplain J, Goodman MD, Popowich D, Orkin BA, Tsichlis PN, Martell R. The First Study Evaluating the Safety of Pre-Surgery Administration of Metformin in Patients with Colorectal and other Gastrointestinal Cancers and Effect on Cancer Stem Cells. Cancer Medicine Journal. 4: 1-10. PMID 34368808   
2021 Gül D, Habtemichael N, Dietrich D, Dietrich J, Gößwein D, Khamis A, Deuss E, Künzel J, Schneider G, Strieth S, Stauber RH. Identification of cytokeratin24 as a tumor suppressor for the management of head and neck cancer. Biological Chemistry. PMID 34450690 DOI: 10.1515/hsz-2021-0287   
2021 Wei B, Yu M, Yao J, Jiang M, An J, Yang J, Lin J, Zhao Y, Zhu Y. Multidimensional Analyses of Tumor Immune Microenvironment Reveal the Possible Rationality of Immunotherapy and Identify High Immunotherapy Response Subtypes for Renal Papillary Cell Carcinoma. Frontiers in Immunology. 12: 657951. PMID 34531849 DOI: 10.3389/fimmu.2021.657951   
2021 Wong C, Li B. AutoCAT: Automated cancer-associated TCRs discovery from TCR-seq data. Bioinformatics (Oxford, England). PMID 34529039 DOI: 10.1093/bioinformatics/btab661   
2021 Li J, Xie J, Wu D, Chen L, Gong Z, Wu R, Hu Y, Zhao J, Xu Y. A pan-cancer analysis revealed the role of the SLC16 family in cancer. Channels (Austin, Tex.). 15: 528-540. PMID 34424811 DOI: 10.1080/19336950.2021.1965422   
2021 Vyas D, Patel M, Wairkar S. Strategies for active tumor targeting-an update. European Journal of Pharmacology. 174512. PMID 34555395 DOI: 10.1016/j.ejphar.2021.174512   
2021 Abdoli Shadbad M, Hosseinkhani N, Asadzadeh Z, Derakhshani A, Karim Ahangar N, Hemmat N, Lotfinejad P, Brunetti O, Silvestris N, Baradaran B. A Systematic Review to Clarify the Prognostic Values of CD44 and CD44CD24 Phenotype in Triple-Negative Breast Cancer Patients: Lessons Learned and The Road Ahead. Frontiers in Oncology. 11: 689839. PMID 34434894 DOI: 10.3389/fonc.2021.689839   
2021 Martin B, Greinacher A, Bülow R, Hammer F, Hoene A, Burchardt M, Zimmermann U. Acute myocardial infarction and arterial embolism in a patient with newly diagnosed renal mass: management dilemmas! A case report. Bmc Urology. 21: 111. PMID 34407783 DOI: 10.1186/s12894-021-00870-z   
2021 Lôbo GCNB, Paiva KLR, Silva ALG, Simões MM, Radicchi MA, Báo SN. Nanocarriers Used in Drug Delivery to Enhance Immune System in Cancer Therapy. Pharmaceutics. 13. PMID 34452128 DOI: 10.3390/pharmaceutics13081167   
2021 Goel NJ, Bird CE, Hicks WH, Abdullah KG. Economic implications of the modern treatment paradigm of glioblastoma: an analysis of global cost estimates and their utility for cost assessment. Journal of Medical Economics. 24: 1018-1024. PMID 34353213 DOI: 10.1080/13696998.2021.1964775   
2021 Abdin SM, Paasch D, Morgan M, Lachmann N. CARs and beyond: tailoring macrophage-based cell therapeutics to combat solid malignancies. Journal For Immunotherapy of Cancer. 9. PMID 34462325 DOI: 10.1136/jitc-2021-002741   
2021 Jeong J, Kim DK, Park JH, Park DJ, Lee HJ, Yang HK, Kong SH, Jung K. Tumor-Infiltrating Neutrophils and Non-Classical Monocytes May Be Potential Therapeutic Targets for HER2 Gastric Cancer. Immune Network. 21: e31. PMID 34522444 DOI: 10.4110/in.2021.21.e31   
2021 Bayir Garbioglu D, Demir N, Ozel C, Avci H, Dincer M. Determination of therapeutic agents efficiencies of microsatellite instability high colon cancer cells in post-metastatic liver biochip modeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21834. PMID 34403553 DOI: 10.1096/fj.202100333R   
2021 Hsieh RW, Borson S, Tsagianni A, Zandberg DP. Immunotherapy in Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck. Frontiers in Oncology. 11: 705614. PMID 34540672 DOI: 10.3389/fonc.2021.705614   
2021 Rawding PA, Bu J, Wang J, Kim DW, Drelich AJ, Kim Y, Hong S. Dendrimers for cancer immunotherapy: Avidity-based drug delivery vehicles for effective anti-tumor immune response. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. e1752. PMID 34414690 DOI: 10.1002/wnan.1752   
2021 Brun S, Pascussi JM, Gifu EP, Bestion E, Macek-Jilkova Z, Wang G, Bassissi F, Mezouar S, Courcambeck J, Merle P, Decaens T, Pannequin J, Halfon P, Caron de Fromentel C. GNS561, a New Autophagy Inhibitor Active against Cancer Stem Cells in Hepatocellular Carcinoma and Hepatic Metastasis from Colorectal Cancer. Journal of Cancer. 12: 5432-5438. PMID 34405006 DOI: 10.7150/jca.58533   
2021 Hu LF, Yang X, Lan HR, Fang XL, Chen XY, Jin KT. Preclinical tumor organoid models in personalized cancer therapy: Not Everyone Fits the Mold. Experimental Cell Research. 112858. PMID 34600901 DOI: 10.1016/j.yexcr.2021.112858   
2021 Cheng L, Creasy T, Pilataxi F, Greenlees L, Vence L, Sridhar S, Streicher K. Effects of combination treatment with durvalumab plus tremelimumab on the tumor microenvironment in non-small-cell lung carcinoma. Cancer Immunology, Immunotherapy : Cii. PMID 34623465 DOI: 10.1007/s00262-021-03065-5   
2021 Fan YF, Shang WT, Lu GH, Guo KX, Deng H, Zhu XH, Wang CC, Tian J. Decreasing hyaluronic acid combined with drug-loaded nanoprobes improve the delivery and efficacy of chemotherapeutic drugs for pancreatic cancer. Cancer Letters. PMID 34530049 DOI: 10.1016/j.canlet.2021.09.016