Kevin W. Plaxco - Publications

Affiliations: 
Chemistry & Biochemistry University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
biomolecular physics, biomolecular engineering
Website:
http://web.chem.ucsb.edu/~plaxcogroup/?page_id=11

197 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Idili A, Arroyo-Currás N, Ploense KL, Csordas AT, Kuwahara M, Kippin TE, Plaxco KW. Seconds-resolved pharmacokinetic measurements of the chemotherapeutic irinotecan in the living body. Chemical Science. 10: 8164-8170. PMID 31673321 DOI: 10.1039/c9sc01495k  0.88
2019 Dauphin-Ducharme P, Yang K, Arroyo-Curras N, Ploense KL, Zhang Y, Gerson J, Kurnik M, Kippin TE, Stojanovic MN, Plaxco KW. Electrochemical Aptamer-based Sensors for Improved Therapeutic Drug Monitoring and High-Precision, Feedback-controlled Drug Delivery. Acs Sensors. PMID 31556293 DOI: 10.1021/acssensors.9b01616  0.88
2019 Vieira PA, Shin CB, Arroyo-Currás N, Ortega G, Li W, Keller AA, Plaxco KW, Kippin TE. Ultra-High-Precision, Pharmacokinetic Measurements Highlight the Need for and a Route Toward More Highly Personalized Medicine. Frontiers in Molecular Biosciences. 6: 69. PMID 31475156 DOI: 10.3389/fmolb.2019.00069  0.88
2019 Curtis SD, Ploense KL, Kurnik M, Ortega G, Parolo C, Kippin TE, Plaxco KW, Arroyo-Curras N. Open Source Software for the Real-Time Control, Processing and Visualization of High-Volume Electrochemical Data. Analytical Chemistry. PMID 31462040 DOI: 10.1021/acs.analchem.9b02553  0.88
2019 Ogden NE, Kurnik M, Parolo C, Plaxco KW. An electrochemical scaffold sensor for rapid syphilis diagnosis. The Analyst. PMID 31369000 DOI: 10.1039/c9an00455f  0.64
2019 Scida K, Plaxco KW, Jamieson BG. High frequency, real-time neurochemical and neuropharmacological measurements in situ in the living body. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 31361988 DOI: 10.1016/j.trsl.2019.07.004  0.68
2019 Dauphin-Ducharme P, Arroyo-Currás N, Plaxco KW. Correction to "High-Precision Electrochemical Measurements of the Guanine-, Mismatch-, and Length-Dependence of Electron Transfer from Electrode-Bound DNA Are Consistent with a Contact-Mediated Mechanism". Journal of the American Chemical Society. PMID 31045361 DOI: 10.1021/jacs.9b03972  0.88
2019 Riback JA, Bowman MA, Zmyslowski AM, Plaxco KW, Clark PL, Sosnick TR. Commonly used FRET fluorophores promote collapse of an otherwise disordered protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 30992378 DOI: 10.1073/pnas.1813038116  0.52
2019 Idili A, Gerson J, Parolo C, Kippin T, Plaxco KW. An electrochemical aptamer-based sensor for the rapid and convenient measurement of L-tryptophan. Analytical and Bioanalytical Chemistry. PMID 30796485 DOI: 10.1007/s00216-019-01645-0  0.8
2019 Dauphin-Ducharme P, Arroyo-Curras N, Plaxco KW. High-precision electrochemical measurements of the guanine-, mismatch- and length-dependence of electron transfer from electrode-bound DNA are consistent with a contact-mediated mechanism. Journal of the American Chemical Society. PMID 30605323 DOI: 10.1021/jacs.8b11341  0.68
2018 Ortega G, Kurnik M, Dauphin-Ducharme P, Li H, Arroyo-Currás N, Caceres A, Plaxco K. Surface Attachment Enhances the Thermodynamic Stability of Protein L. Angewandte Chemie (International Ed. in English). PMID 30549169 DOI: 10.1002/anie.201812231  0.92
2018 Li H, Somerson J, Xia F, Plaxco KW. Electrochemical DNA-based sensors for molecular quality control: continuous, real-time melamine detection in flowing whole milk. Analytical Chemistry. PMID 30141321 DOI: 10.1021/acs.analchem.8b01993  1
2018 Kurnik M, Ortega G, Dauphin-Ducharme P, Li H, Caceres A, Plaxco KW. Quantitative measurements of protein-surface interaction thermodynamics. Proceedings of the National Academy of Sciences of the United States of America. PMID 30061388 DOI: 10.1073/pnas.1800287115  0.92
2018 Watkins HM, Ricci F, Plaxco KW. Experimental Measurement of Surface Charge Effects on the Stability of a Surface-Bound Biopolymer. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29972737 DOI: 10.1021/acs.langmuir.8b01004  0.8
2018 Kang D, Parolo C, Sun S, Ogden N, Dahlquist FW, Plaxco KW. Expanding the scope of protein-detecting electrochemical DNA "scaffold" sensors. Acs Sensors. PMID 29877078 DOI: 10.1021/acssensors.8b00311  0.88
2018 Simon AJ, Walls-Smith LT, Plaxco KW. Exploiting the conformational-selection mechanism to control the response kinetics of a "smart" DNA hydrogel. The Analyst. PMID 29713702 DOI: 10.1039/c8an00337h  0.8
2018 Somerson J, Plaxco KW. Electrochemical Aptamer-Based Sensors for Rapid Point-of-Use Monitoring of the Mycotoxin Ochratoxin A Directly in a Food Stream. Molecules (Basel, Switzerland). 23. PMID 29662036 DOI: 10.3390/molecules23040912  0.92
2017 Arroyo-Curras N, Dauphin-Ducharme P, Ortega G, Ploense KL, Kippin TE, Plaxco KW. Sub-second-resolved molecular measurements in the living body using chronoamperometrically interrogated aptamer-based sensors. Acs Sensors. PMID 29124939 DOI: 10.1021/acssensors.7b00787  0.88
2017 Arroyo-Curras N, Scida K, Ploense KL, Kippin TE, Plaxco KW. High surface area electrodes generated via electrochemical roughening improve the signaling of electrochemical aptamer-based biosensors. Analytical Chemistry. PMID 29076341 DOI: 10.1021/acs.analchem.7b02830  0.88
2017 Kang D, Sun S, Kurnik M, Morales DP, Dahlquist FW, Plaxco KW. A new architecture for reagentless, protein-based electro-chemical biosensors. Journal of the American Chemical Society. PMID 28789522 DOI: 10.1021/jacs.7b05953  0.88
2017 Li H, Dauphin-Ducharme P, Ortega G, Plaxco KW. Calibration-free electrochemical biosensors supporting accurate molecular measurements directly in undiluted whole blood. Journal of the American Chemical Society. PMID 28712286 DOI: 10.1021/jacs.7b05412  0.92
2017 Dauphin-Ducharme P, Arroyo-Curras N, Kurnik M, Ortega G, Li H, Plaxco KW. A Simulation-based Approach to Determining Electron Transfer Rates using Square-Wave Voltammetry. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 28391695 DOI: 10.1021/acs.langmuir.7b00359  0.92
2017 Mariottini D, Idili A, Vallée-Bélisle A, Plaxco KW, Ricci F. A DNA nanodevice that loads and releases a cargo with hemoglobin-like allosteric control and cooperativity. Nano Letters. PMID 28387120 DOI: 10.1021/acs.nanolett.7b00814  0.96
2017 Li H, Dauphin-Ducharme P, Arroyo-Currás N, Tran CH, Vieira PA, Li S, Shin C, Somerson J, Kippin TE, Plaxco KW. A Biomimetic Phosphatidylcholine-Terminated Monolayer Greatly Improves the In Vivo Performance of Electrochemical Aptamer-Based Sensors. Angewandte Chemie (International Ed. in English). PMID 28371090 DOI: 10.1002/anie.201700748  0.92
2017 Arroyo-Currás N, Somerson J, Vieira PA, Ploense KL, Kippin TE, Plaxco KW. Real-time measurement of small molecules directly in awake, ambulatory animals. Proceedings of the National Academy of Sciences of the United States of America. PMID 28069939 DOI: 10.1073/pnas.1613458114  0.92
2016 Mao X, Simon AJ, Pei H, Shi J, Li J, Huang Q, Plaxco KW, Fan C. Activity modulation and allosteric control of a scaffolded DNAzyme using a dynamic DNA nanostructure. Chemical Science. 7: 1200-1204. PMID 29910875 DOI: 10.1039/c5sc03705k  1
2016 Simon AJ, Walls-Smith LT, Freddi MJ, Fong FY, Gubala V, Plaxco KW. Simultaneous Measurement of the Dissolution Kinetics of Responsive DNA Hydrogels at Multiple Length Scales. Acs Nano. PMID 28006092 DOI: 10.1021/acsnano.6b06414  0.8
2016 Li H, Arroyo-Currás N, Kang D, Ricci F, Plaxco KW. Dual-Reporter Drift Correction To Enhance the Performance of Electrochemical Aptamer-Based Sensors in Whole Blood. Journal of the American Chemical Society. 138: 15809-15812. PMID 27960346 DOI: 10.1021/jacs.6b08671  0.92
2016 Dauphin-Ducharme P, Plaxco KW. Maximizing the Signal Gain of Electrochemical-DNA Sensors. Analytical Chemistry. PMID 27805364 DOI: 10.1021/acs.analchem.6b03227  0.64
2016 Kang D, Ricci F, White RJ, Plaxco KW. A survey of redox-active moieties for application in multiplexed electrochemical biosensors. Analytical Chemistry. PMID 27659949 DOI: 10.1021/acs.analchem.6b02376  1
2016 Ricci F, Vallée-Bélisle A, Simon AJ, Porchetta A, Plaxco KW. Using Nature's "Tricks" To Rationally Tune the Binding Properties of Biomolecular Receptors. Accounts of Chemical Research. PMID 27564548 DOI: 10.1021/acs.accounts.6b00276  0.96
2015 Ranallo S, Rossetti M, Plaxco KW, Vallée-Bélisle A, Ricci F. A Modular, DNA-Based Beacon for Single-Step Fluorescence Detection of Antibodies and Other Proteins. Angewandte Chemie (International Ed. in English). 54: 13214-8. PMID 26337144 DOI: 10.1002/anie.201505179  1
2015 Watkins HM, Simon AJ, Sosnick TR, Lipman EA, Hjelm RP, Plaxco KW. Random coil negative control reproduces the discrepancy between scattering and FRET measurements of denatured protein dimensions. Proceedings of the National Academy of Sciences of the United States of America. 112: 6631-6. PMID 25964362 DOI: 10.1073/pnas.1418673112  1
2015 Vinh NQ, Sherwin MS, Allen SJ, George DK, Rahmani AJ, Plaxco KW. High-precision gigahertz-to-terahertz spectroscopy of aqueous salt solutions as a probe of the femtosecond-to-picosecond dynamics of liquid water. The Journal of Chemical Physics. 142: 164502. PMID 25933769 DOI: 10.1063/1.4918708  1
2015 Hsieh K, Ferguson BS, Eisenstein M, Plaxco KW, Soh HT. Integrated electrochemical microsystems for genetic detection of pathogens at the point of care. Accounts of Chemical Research. 48: 911-20. PMID 25785632 DOI: 10.1021/ar500456w  1
2015 Adornetto G, Porchetta A, Palleschi G, Plaxco KW, Ricci F. A general approach to the design of allosteric, transcription factor-regulated DNAzymes Chemical Science. 6: 3692-3696. DOI: 10.1039/c5sc00228a  1
2015 Hsieh K, Scott Ferguson B, Eisenstein M, Plaxco KW, Tom Soh H. Integrated electrochemical microsystems for genetic detection of pathogens at the point of care Accounts of Chemical Research. 48: 911-920. DOI: 10.1021/ar500456  1
2014 Simon AJ, Vallée-Bélisle A, Ricci F, Plaxco KW. Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 15048-53. PMID 25288724 DOI: 10.1073/pnas.1410796111  1
2014 Simon AJ, Vallée-Bélisle A, Ricci F, Watkins HM, Plaxco KW. Using the population-shift mechanism to rationally introduce "Hill-type" cooperativity into a normally non-cooperative receptor. Angewandte Chemie (International Ed. in English). 53: 9471-5. PMID 25044647 DOI: 10.1002/anie.201403777  1
2014 Watkins HM, Simon AJ, Ricci F, Plaxco KW. Effects of crowding on the stability of a surface-tethered biopolymer: an experimental study of folding in a highly crowded regime. Journal of the American Chemical Society. 136: 8923-7. PMID 24919057 DOI: 10.1021/ja411486g  1
2014 Yang AH, Hsieh K, Patterson AS, Ferguson BS, Eisenstein M, Plaxco KW, Soh HT. Accurate zygote-specific discrimination of single-nucleotide polymorphisms using microfluidic electrochemical DNA melting curves. Angewandte Chemie (International Ed. in English). 53: 3163-7. PMID 24520069 DOI: 10.1002/anie.201310059  1
2014 Lawrence C, Vallée-Bélisle A, Pfeil SH, de Mornay D, Lipman EA, Plaxco KW. A comparison of the folding kinetics of a small, artificially selected DNA aptamer with those of equivalently simple naturally occurring proteins. Protein Science : a Publication of the Protein Society. 23: 56-66. PMID 24285472 DOI: 10.1002/pro.2390  1
2013 Ferguson BS, Hoggarth DA, Maliniak D, Ploense K, White RJ, Woodward N, Hsieh K, Bonham AJ, Eisenstein M, Kippin TE, Plaxco KW, Soh HT. Real-time, aptamer-based tracking of circulating therapeutic agents in living animals. Science Translational Medicine. 5: 213ra165. PMID 24285484 DOI: 10.1126/scitranslmed.3007095  1
2013 Idili A, Plaxco KW, Vallée-Bélisle A, Ricci F. Thermodynamic basis for engineering high-affinity, high-specificity binding-induced DNA clamp nanoswitches. Acs Nano. 7: 10863-9. PMID 24219761 DOI: 10.1021/nn404305e  1
2013 Patterson AS, Hsieh K, Soh HT, Plaxco KW. Electrochemical real-time nucleic acid amplification: towards point-of-care quantification of pathogens. Trends in Biotechnology. 31: 704-12. PMID 24209384 DOI: 10.1016/j.tibtech.2013.09.005  1
2013 Porchetta A, Vallée-Bélisle A, Plaxco KW, Ricci F. Allosterically tunable, DNA-based switches triggered by heavy metals. Journal of the American Chemical Society. 135: 13238-41. PMID 23971651 DOI: 10.1021/ja404653q  1
2013 Bonham AJ, Paden NG, Ricci F, Plaxco KW. Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor. The Analyst. 138: 5580-3. PMID 23905162 DOI: 10.1039/c3an01079a  1
2013 Uzawa T, Isoshima T, Ito Y, Ishimori K, Makarov DE, Plaxco KW. Sequence and temperature dependence of the end-to-end collision dynamics of single-stranded DNA. Biophysical Journal. 104: 2485-92. PMID 23746521 DOI: 10.1016/j.bpj.2013.03.053  1
2013 Esteban Fernández de Ávila B, Watkins HM, Pingarrón JM, Plaxco KW, Palleschi G, Ricci F. Determinants of the detection limit and specificity of surface-based biosensors. Analytical Chemistry. 85: 6593-7. PMID 23713910 DOI: 10.1021/ac4012123  1
2013 Patterson AS, Heithoff DM, Ferguson BS, Soh HT, Mahan MJ, Plaxco KW. Microfluidic chip-based detection and intraspecies strain discrimination of Salmonella serovars derived from whole blood of septic mice. Applied and Environmental Microbiology. 79: 2302-11. PMID 23354710 DOI: 10.1128/AEM.03882-12  1
2012 Porchetta A, Vallée-Bélisle A, Plaxco KW, Ricci F. Using distal-site mutations and allosteric inhibition to tune, extend, and narrow the useful dynamic range of aptamer-based sensors. Journal of the American Chemical Society. 134: 20601-4. PMID 23215257 DOI: 10.1021/ja310585e  1
2012 Ricci F, Vallée-Bélisle A, Porchetta A, Plaxco KW. Rational design of allosteric inhibitors and activators using the population-shift model: in vitro validation and application to an artificial biosensor. Journal of the American Chemical Society. 134: 15177-80. PMID 22924432 DOI: 10.1021/ja304672h  1
2012 Vallée-Bélisle A, Ricci F, Uzawa T, Xia F, Plaxco KW. Bioelectrochemical switches for the quantitative detection of antibodies directly in whole blood. Journal of the American Chemical Society. 134: 15197-200. PMID 22913425 DOI: 10.1021/ja305720w  1
2012 Kang D, Vallée-Bélisle A, Porchetta A, Plaxco KW, Ricci F. Re-engineering electrochemical biosensors to narrow or extend their useful dynamic range. Angewandte Chemie (International Ed. in English). 51: 6717-21. PMID 22674785 DOI: 10.1002/anie.201202204  1
2012 Hsieh K, Patterson AS, Ferguson BS, Plaxco KW, Soh HT. Rapid, sensitive, and quantitative detection of pathogenic DNA at the point of care through microfluidic electrochemical quantitative loop-mediated isothermal amplification. Angewandte Chemie (International Ed. in English). 51: 4896-900. PMID 22488842 DOI: 10.1002/anie.201109115  1
2012 Bonham AJ, Hsieh K, Ferguson BS, Vallée-Bélisle A, Ricci F, Soh HT, Plaxco KW. Quantification of transcription factor binding in cell extracts using an electrochemical, structure-switching biosensor. Journal of the American Chemical Society. 134: 3346-8. PMID 22313286 DOI: 10.1021/ja2115663  1
2012 Yoo TY, Meisburger SP, Hinshaw J, Pollack L, Haran G, Sosnick TR, Plaxco K. Small-angle X-ray scattering and single-molecule FRET spectroscopy produce highly divergent views of the low-denaturant unfolded state. Journal of Molecular Biology. 418: 226-36. PMID 22306460 DOI: 10.1016/j.jmb.2012.01.016  1
2012 Vallée-Bélisle A, Ricci F, Plaxco KW. Engineering biosensors with extended, narrowed, or arbitrarily edited dynamic range. Journal of the American Chemical Society. 134: 2876-9. PMID 22239688 DOI: 10.1021/ja209850j  1
2012 Watkins HM, Vallée-Bélisle A, Ricci F, Makarov DE, Plaxco KW. Entropic and electrostatic effects on the folding free energy of a surface-attached biomolecule: an experimental and theoretical study. Journal of the American Chemical Society. 134: 2120-6. PMID 22239220 DOI: 10.1021/ja208436p  1
2012 Perez Rafael S, Vallée-Bélisle A, Fabregas E, Plaxco K, Palleschi G, Ricci F. Employing the metabolic "branch point effect" to generate an all-or-none, digital-like response in enzymatic outputs and enzyme-based sensors. Analytical Chemistry. 84: 1076-82. PMID 22148353 DOI: 10.1021/ac202701c  1
2012 White RJ, Kallewaard HM, Hsieh W, Patterson AS, Kasehagen JB, Cash KJ, Uzawa T, Soh HT, Plaxco KW. Wash-free, electrochemical platform for the quantitative, multiplexed detection of specific antibodies. Analytical Chemistry. 84: 1098-103. PMID 22145706 DOI: 10.1021/ac202757c  1
2012 Biagiotti V, Porchetta A, Desiderati S, Plaxco KW, Palleschi G, Ricci F. Probe accessibility effects on the performance of electrochemical biosensors employing DNA monolayers. Analytical and Bioanalytical Chemistry. 402: 413-21. PMID 21928081 DOI: 10.1007/s00216-011-5361-0  1
2012 Uddin A, Yemenicioglu S, Chen CH, Corgliano E, Milaninia K, Xia F, Plaxco K, Theogarajan L. Biosensing with integrated CMOS nanopores Proceedings of Spie - the International Society For Optical Engineering. 8460. DOI: 10.1117/12.945553  1
2012 Kang D, White RJ, Xia F, Zuo X, Vallée-Bélisle A, Plaxco KW. DNA biomolecular-electronic encoder and decoder devices constructed by multiplex biosensors Npg Asia Materials. 4. DOI: 10.1038/am.2012.1  1
2011 Zuo X, Xia F, Patterson A, Soh HT, Xiao Y, Plaxco KW. Two-step, PCR-free telomerase detection by using exonuclease III-aided target recycling. Chembiochem : a European Journal of Chemical Biology. 12: 2745-7. PMID 22125097 DOI: 10.1002/cbic.201100592  1
2011 Ricci F, Vallée-Bélisle A, Plaxco KW. High-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networks. Plos Computational Biology. 7: e1002171. PMID 21998566 DOI: 10.1371/journal.pcbi.1002171  1
2011 Hsieh K, White RJ, Ferguson BS, Plaxco KW, Xiao Y, Soh HT. Polarity-switching electrochemical sensor for specific detection of single-nucleotide mismatches. Angewandte Chemie (International Ed. in English). 50: 11176-80. PMID 21976312 DOI: 10.1002/anie.201103482  1
2011 Rowe AA, Chuh KN, Lubin AA, Miller EA, Cook B, Hollis D, Plaxco KW. Electrochemical biosensors employing an internal electrode attachment site and achieving reversible, high gain detection of specific nucleic acid sequences. Analytical Chemistry. 83: 9462-6. PMID 21975121 DOI: 10.1021/ac202171x  1
2011 Rowe AA, Bonham AJ, White RJ, Zimmer MP, Yadgar RJ, Hobza TM, Honea JW, Ben-Yaacov I, Plaxco KW. CheapStat: an open-source, "do-it-yourself" potentiostat for analytical and educational applications. Plos One. 6: e23783. PMID 21931613 DOI: 10.1371/journal.pone.0023783  1
2011 Vallée-Bélisle A, Bonham AJ, Reich NO, Ricci F, Plaxco KW. Transcription factor beacons for the quantitative detection of DNA binding activity. Journal of the American Chemical Society. 133: 13836-9. PMID 21815647 DOI: 10.1021/ja204775k  1
2011 Rowe AA, White RJ, Bonham AJ, Plaxco KW. Fabrication of electrochemical-DNA biosensors for the reagentless detection of nucleic acids, proteins and small molecules. Journal of Visualized Experiments : Jove. PMID 21673639 DOI: 10.3791/2922  1
2011 Vinh NQ, Allen SJ, Plaxco KW. Dielectric spectroscopy of proteins as a quantitative experimental test of computational models of their low-frequency harmonic motions. Journal of the American Chemical Society. 133: 8942-7. PMID 21542634 DOI: 10.1021/ja200566u  1
2011 Plaxco KW, Soh HT. Switch-based biosensors: a new approach towards real-time, in vivo molecular detection. Trends in Biotechnology. 29: 1-5. PMID 21106266 DOI: 10.1016/j.tibtech.2010.10.005  1
2011 Abelow AE, White RJ, Plaxco KW, Zharov I. Nanoporous silica colloidal films with molecular transport gated by aptamers responsive to small molecules Collection of Czechoslovak Chemical Communications. 76: 683-694. DOI: 10.1135/cccc2011022  1
2010 Cheng RR, Uzawa T, Plaxco KW, Makarov DE. Universality in the timescales of internal loop formation in unfolded proteins and single-stranded oligonucleotides. Biophysical Journal. 99: 3959-68. PMID 21156138 DOI: 10.1016/j.bpj.2010.11.017  1
2010 Uzawa T, Cheng RR, White RJ, Makarov DE, Plaxco KW. A mechanistic study of electron transfer from the distal termini of electrode-bound, single-stranded DNAs. Journal of the American Chemical Society. 132: 16120-6. PMID 20964337 DOI: 10.1021/ja106345d  1
2010 Plaxco KW. The art of writing science. Protein Science : a Publication of the Protein Society. 19: 2261-6. PMID 20954234 DOI: 10.1002/pro.514  1
2010 Patterson A, Caprio F, Vallée-Bélisle A, Moscone D, Plaxco KW, Palleschi G, Ricci F. Using triplex-forming oligonucleotide probes for the reagentless, electrochemical detection of double-stranded DNA. Analytical Chemistry. 82: 9109-15. PMID 20936782 DOI: 10.1021/ac1024528  1
2010 Xiao Y, Dane KY, Uzawa T, Csordas A, Qian J, Soh HT, Daugherty PS, Lagally ET, Heeger AJ, Plaxco KW. Detection of telomerase activity in high concentration of cell lysates using primer-modified gold nanoparticles. Journal of the American Chemical Society. 132: 15299-307. PMID 20932008 DOI: 10.1021/ja106513f  1
2010 Xia F, White RJ, Zuo X, Patterson A, Xiao Y, Kang D, Gong X, Plaxco KW, Heeger AJ. An electrochemical supersandwich assay for sensitive and selective DNA detection in complex matrices. Journal of the American Chemical Society. 132: 14346-8. PMID 20873767 DOI: 10.1021/ja104998m  1
2010 Abelow AE, Schepelina O, White RJ, Vallée-Bélisle A, Plaxco KW, Zharov I. Biomimetic glass nanopores employing aptamer gates responsive to a small molecule. Chemical Communications (Cambridge, England). 46: 7984-6. PMID 20865192 DOI: 10.1039/c0cc02649b  1
2010 Lawrence C, Kuge J, Ahmad K, Plaxco KW. Investigation of an anomalously accelerating substitution in the folding of a prototypical two-state protein. Journal of Molecular Biology. 403: 446-58. PMID 20816985 DOI: 10.1016/j.jmb.2010.08.049  1
2010 Rowe AA, Miller EA, Plaxco KW. Reagentless measurement of aminoglycoside antibiotics in blood serum via an electrochemical, ribonucleic acid aptamer-based biosensor. Analytical Chemistry. 82: 7090-5. PMID 20687587 DOI: 10.1021/ac101491d  1
2010 Vallée-Bélisle A, Plaxco KW. Structure-switching biosensors: inspired by Nature. Current Opinion in Structural Biology. 20: 518-26. PMID 20627702 DOI: 10.1016/j.sbi.2010.05.001  1
2010 Xia F, Zuo X, Yang R, Xiao Y, Kang D, Vallée-Bélisle A, Gong X, Yuen JD, Hsu BB, Heeger AJ, Plaxco KW. Colorimetric detection of DNA, small molecules, proteins, and ions using unmodified gold nanoparticles and conjugated polyelectrolytes. Proceedings of the National Academy of Sciences of the United States of America. 107: 10837-41. PMID 20534499 DOI: 10.1073/pnas.1005632107  1
2010 Xia F, Zuo X, Yang R, White RJ, Xiao Y, Kang D, Gong X, Lubin AA, Vallée-Bélisle A, Yuen JD, Hsu BY, Plaxco KW. Label-free, dual-analyte electrochemical biosensors: a new class of molecular-electronic logic gates. Journal of the American Chemical Society. 132: 8557-9. PMID 20527878 DOI: 10.1021/ja101379k  1
2010 Lubin AA, Plaxco KW. Folding-based electrochemical biosensors: the case for responsive nucleic acid architectures. Accounts of Chemical Research. 43: 496-505. PMID 20201486 DOI: 10.1021/ar900165x  1
2010 Ricci F, Adornetto G, Moscone D, Plaxco KW, Palleschi G. Quantitative, reagentless, single-step electrochemical detection of anti-DNA antibodies directly in blood serum. Chemical Communications (Cambridge, England). 46: 1742-4. PMID 20177635 DOI: 10.1039/b922595a  1
2010 White RJ, Rowe AA, Plaxco KW. Re-engineering aptamers to support reagentless, self-reporting electrochemical sensors. The Analyst. 135: 589-94. PMID 20174715 DOI: 10.1039/b921253a  1
2010 Wickersham CE, Cash KJ, Pfeil SH, Bruck I, Kaplan DL, Plaxco KW, Lipman EA. Tracking a molecular motor with a nanoscale optical encoder. Nano Letters. 10: 1022-7. PMID 20121107 DOI: 10.1021/nl904192m  1
2010 Zuo X, Xia F, Xiao Y, Plaxco KW. Sensitive and selective amplified fluorescence DNA detection based on exonuclease III-aided target recycling. Journal of the American Chemical Society. 132: 1816-8. PMID 20092337 DOI: 10.1021/ja909551b  1
2010 Xia F, Zuo X, Yang R, Xiao Y, Kang D, Vallée-Bélisle A, Gong X, Heeger AJ, Plaxco KW. On the binding of cationic, water-soluble conjugated polymers to DNA: electrostatic and hydrophobic interactions. Journal of the American Chemical Society. 132: 1252-4. PMID 20058862 DOI: 10.1021/ja908890q  1
2010 White RJ, Plaxco KW. Exploiting binding-induced changes in probe flexibility for the optimization of electrochemical biosensors. Analytical Chemistry. 82: 73-6. PMID 20000457 DOI: 10.1021/ac902595f  1
2010 Kahn K, Plaxco KW. Principles of biomolecular recognition Recognition Receptors in Biosensors. 3-45. DOI: 10.1007/978-1-4419-0919-0_1  1
2009 White RJ, Plaxco KW. Engineering New Aptamer Geometries for Electrochemical Aptamer-Based Sensors. Proceedings of Spie--the International Society For Optical Engineering. 7321: 732105. PMID 20436792 DOI: 10.1117/12.820419  1
2009 Xiao Y, Uzawa T, White RJ, Demartini D, Plaxco KW. On the Signaling of Electrochemical Aptamer-Based Sensors: Collision- and Folding-Based Mechanisms. Electroanalysis. 21: 1267-1271. PMID 20436787 DOI: 10.1002/elan.200804564  1
2009 Cash KJ, Ricci F, Plaxco KW. A general electrochemical method for label-free screening of protein-small molecule interactions. Chemical Communications (Cambridge, England). 6222-4. PMID 19826675 DOI: 10.1039/b911558g  1
2009 Kang D, Zuo X, Yang R, Xia F, Plaxco KW, White RJ. Comparing the properties of electrochemical-based DNA sensors employing different redox tags. Analytical Chemistry. 81: 9109-13. PMID 19810694 DOI: 10.1021/ac901811n  1
2009 Xiao Y, Lou X, Uzawa T, Plakos KJ, Plaxco KW, Soh HT. An electrochemical sensor for single nucleotide polymorphism detection in serum based on a triple-stem DNA probe. Journal of the American Chemical Society. 131: 15311-6. PMID 19807078 DOI: 10.1021/ja905068s  1
2009 Cheng RR, Uzawa T, Plaxco KW, Makarov DE. The rate of intramolecular loop formation in DNA and polypeptides: the absence of the diffusion-controlled limit and fractional power-law viscosity dependence. The Journal of Physical Chemistry. B. 113: 14026-34. PMID 19780594 DOI: 10.1021/jp902291n  1
2009 Kohn JE, Gillespie B, Plaxco KW. Non-sequence-specific interactions can account for the compaction of proteins unfolded under "native" conditions. Journal of Molecular Biology. 394: 343-50. PMID 19751743 DOI: 10.1016/j.jmb.2009.09.005  1
2009 Makarov DE, Plaxco KW. Measuring distances within unfolded biopolymers using fluorescence resonance energy transfer: The effect of polymer chain dynamics on the observed fluorescence resonance energy transfer efficiency. The Journal of Chemical Physics. 131: 085105. PMID 19725638 DOI: 10.1063/1.3212602  1
2009 Vallée-Bélisle A, Ricci F, Plaxco KW. Thermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors. Proceedings of the National Academy of Sciences of the United States of America. 106: 13802-7. PMID 19666496 DOI: 10.1073/pnas.0904005106  1
2009 Uzawa T, Cheng RR, Cash KJ, Makarov DE, Plaxco KW. The length and viscosity dependence of end-to-end collision rates in single-stranded DNA. Biophysical Journal. 97: 205-10. PMID 19580758 DOI: 10.1016/j.bpj.2009.04.036  1
2009 Xiao Y, Plakos KJ, Lou X, White RJ, Qian J, Plaxco KW, Soh HT. Fluorescence detection of single-nucleotide polymorphisms with a single, self-complementary, triple-stem DNA probe. Angewandte Chemie (International Ed. in English). 48: 4354-8. PMID 19431180 DOI: 10.1002/anie.200900369  1
2009 Zuo X, Xiao Y, Plaxco KW. High specificity, electrochemical sandwich assays based on single aptamer sequences and suitable for the direct detection of small-molecule targets in blood and other complex matrices. Journal of the American Chemical Society. 131: 6944-5. PMID 19419171 DOI: 10.1021/ja901315w  1
2009 Cash KJ, Ricci F, Plaxco KW. An electrochemical sensor for the detection of protein-small molecule interactions directly in serum and other complex matrices. Journal of the American Chemical Society. 131: 6955-7. PMID 19413316 DOI: 10.1021/ja9011595  1
2009 Ricci F, Zari N, Caprio F, Recine S, Amine A, Moscone D, Palleschi G, Plaxco KW. Surface chemistry effects on the performance of an electrochemical DNA sensor. Bioelectrochemistry (Amsterdam, Netherlands). 76: 208-13. PMID 19362061 DOI: 10.1016/j.bioelechem.2009.03.007  1
2009 Swensen JS, Xiao Y, Ferguson BS, Lubin AA, Lai RY, Heeger AJ, Plaxco KW, Soh HT. Continuous, real-time monitoring of cocaine in undiluted blood serum via a microfluidic, electrochemical aptamer-based sensor. Journal of the American Chemical Society. 131: 4262-6. PMID 19271708 DOI: 10.1021/ja806531z  1
2009 Lubin AA, Hunt BV, White RJ, Plaxco KW. Effects of probe length, probe geometry, and redox-tag placement on the performance of the electrochemical E-DNA sensor. Analytical Chemistry. 81: 2150-8. PMID 19215066 DOI: 10.1021/ac802317k  1
2009 Ricci F, Bonham AJ, Mason AC, Reich NO, Plaxco KW. Reagentless, electrochemical approach for the specific detection of double- and single-stranded DNA binding proteins. Analytical Chemistry. 81: 1608-14. PMID 19199570 DOI: 10.1021/ac802365x  1
2009 Oh KJ, Cash KJ, Plaxco KW. Beyond molecular beacons: optical sensors based on the binding-induced folding of proteins and polypeptides. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 2244-51. PMID 19191230 DOI: 10.1002/chem.200701748  1
2009 Plaxco KW, Gross M. Protein complexes: the evolution of symmetry. Current Biology : Cb. 19: R25-6. PMID 19138586 DOI: 10.1016/j.cub.2008.11.004  1
2009 Phares N, White RJ, Plaxco KW. Improving the stability and sensing of electrochemical biosensors by employing trithiol-anchoring groups in a six-carbon self-assembled monolayer. Analytical Chemistry. 81: 1095-100. PMID 19133790 DOI: 10.1021/ac8021983  1
2009 Cash KJ, Heeger AJ, Plaxco KW, Xiao Y. Optimization of a reusable, DNA pseudoknot-based electrochemical sensor for sequence-specific DNA detection in blood serum. Analytical Chemistry. 81: 656-61. PMID 19093760 DOI: 10.1021/ac802011d  1
2009 Ruczinski I, Plaxco KW. Some recommendations for the practitioner to improve the precision of experimentally determined protein folding rates and phi values. Proteins. 74: 461-74. PMID 18655053 DOI: 10.1002/prot.22155  1
2008 Pavel I, McCarney E, Elkhaled A, Morrill A, Plaxco K, Moskovits M. Label-Free SERS Detection of Small Proteins Modified to Act as Bifunctional Linkers. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. 112: 4880-4883. PMID 19424458 DOI: 10.1021/jp710261y  1
2008 White RJ, Phares N, Lubin AA, Xiao Y, Plaxco KW. Optimization of electrochemical aptamer-based sensors via optimization of probe packing density and surface chemistry. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 10513-8. PMID 18690727 DOI: 10.1021/la800801v  1
2008 Pavlovic E, Lai RY, Wu TT, Ferguson BS, Sun R, Plaxco KW, Soh HT. Microfluidic device architecture for electrochemical patterning and detection of multiple DNA sequences. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 1102-7. PMID 18181654 DOI: 10.1021/la702681c  1
2008 Feil T, Uzawa T, Plaxco KW, Allen SJ. Studying protein dynamics in aqueous solutions through linear and non-linear THz spectroscopy 33rd International Conference On Infrared and Millimeter Waves and the 16th International Conference On Terahertz Electronics, 2008, Irmmw-Thz 2008. DOI: 10.1109/ICIMW.2008.4665743  1
2008 Ricci F, Plaxco KW. E-DNA sensors for convenient, label-free electrochemical detection of hybridization Microchimica Acta. 163: 149-155. DOI: 10.1007/s00604-008-0015-4  1
2007 Oh KJ, Cash KJ, Lubin AA, Plaxco KW. Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons. Chemical Communications (Cambridge, England). 4869-71. PMID 18361352 DOI: 10.1039/b709776j  1
2007 Xiao Y, Lai RY, Plaxco KW. Preparation of electrode-immobilized, redox-modified oligonucleotides for electrochemical DNA and aptamer-based sensing. Nature Protocols. 2: 2875-80. PMID 18007622 DOI: 10.1038/nprot.2007.413  1
2007 Ricci F, Lai RY, Plaxco KW. Linear, redox modified DNA probes as electrochemical DNA sensors. Chemical Communications (Cambridge, England). 3768-70. PMID 17851622 DOI: 10.1039/b708882e  1
2007 Xiao Y, Qu X, Plaxco KW, Heeger AJ. Label-free electrochemical detection of DNA in blood serum via target-induced resolution of an electrode-bound DNA pseudoknot. Journal of the American Chemical Society. 129: 11896-7. PMID 17850085 DOI: 10.1021/ja074218y  1
2007 Ricci F, Lai RY, Heeger AJ, Plaxco KW, Sumner JJ. Effect of molecular crowding on the response of an electrochemical DNA sensor. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 6827-34. PMID 17488132 DOI: 10.1021/la700328r  1
2007 Oh KJ, Cash KJ, Hugenberg V, Plaxco KW. Peptide beacons: a new design for polypeptide-based optical biosensors. Bioconjugate Chemistry. 18: 607-9. PMID 17461545 DOI: 10.1021/bc060319u  1
2007 Wang Z, Plaxco KW, Makarov DE. Influence of local and residual structures on the scaling behavior and dimensions of unfolded proteins. Biopolymers. 86: 321-8. PMID 17450572 DOI: 10.1002/bip.20747  1
2007 Werner JH, McCarney ER, Keller RA, Plaxco KW, Goodwin PM. Increasing the resolution of single pair fluorescence resonance energy transfer measurements in solution via molecular cytometry. Analytical Chemistry. 79: 3509-13. PMID 17385843 DOI: 10.1021/ac070142c  1
2007 Xiao Y, Rowe AA, Plaxco KW. Electrochemical detection of parts-per-billion lead via an electrode-bound DNAzyme assembly. Journal of the American Chemical Society. 129: 262-3. PMID 17212391 DOI: 10.1021/ja067278x  1
2007 Lai RY, Plaxco KW, Heeger AJ. Aptamer-based electrochemical detection of picomolar platelet-derived growth factor directly in blood serum. Analytical Chemistry. 79: 229-33. PMID 17194144 DOI: 10.1021/ac061592s  1
2007 Xu J, Plaxco KW, Allen SJ. THz spectroscopy of proteins in water: Direct absorption and circular dichroism International Journal of High Speed Electronics and Systems. 17: 709-718. DOI: 10.1142/S0129156407004916  1
2007 Xu J, Plaxco KW, Allen SJ, Bjarnason JE, Brown ER. 0.15-3.72 THz absorption of aqueous salts and saline solutions Applied Physics Letters. 90. DOI: 10.1063/1.2430781  1
2006 Lai RY, Seferos DS, Heeger AJ, Bazan GC, Plaxco KW. Comparison of the signaling and stability of electrochemical DNA sensors fabricated from 6- or 11-carbon self-assembled monolayers. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 10796-800. PMID 17129062 DOI: 10.1021/la0611817  1
2006 Xu J, Plaxco KW, Allen SJ. Collective dynamics of lysozyme in water: terahertz absorption spectroscopy and comparison with theory. The Journal of Physical Chemistry. B. 110: 24255-9. PMID 17125398 DOI: 10.1021/jp064830w  1
2006 Xiao Y, Lubin AA, Baker BR, Plaxco KW, Heeger AJ. Single-step electronic detection of femtomolar DNA by target-induced strand displacement in an electrode-bound duplex. Proceedings of the National Academy of Sciences of the United States of America. 103: 16677-80. PMID 17065320 DOI: 10.1073/pnas.0607693103  1
2006 Oh KJ, Cash KJ, Plaxco KW. Excimer-based peptide beacons: a convenient experimental approach for monitoring polypeptide-protein and polypeptide-oligonucleotide interactions. Journal of the American Chemical Society. 128: 14018-9. PMID 17061871 DOI: 10.1021/ja0651310  1
2006 Ruczinski I, Sosnick TR, Plaxco KW. Methods for the accurate estimation of confidence intervals on protein folding phi-values. Protein Science : a Publication of the Protein Society. 15: 2257-64. PMID 17008714 DOI: 10.1110/ps.062230106  1
2006 Lubin AA, Lai RY, Baker BR, Heeger AJ, Plaxco KW. Sequence-specific, electronic detection of oligonucleotides in blood, soil, and foodstuffs with the reagentless, reusable E-DNA sensor. Analytical Chemistry. 78: 5671-7. PMID 16906710 DOI: 10.1021/ac0601819  1
2006 Faísca PF, Plaxco KW. Cooperativity and the origins of rapid, single-exponential kinetics in protein folding. Protein Science : a Publication of the Protein Society. 15: 1608-18. PMID 16815915 DOI: 10.1110/ps.062180806  1
2006 Xu J, Plaxco KW, Allen SJ. Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy. Protein Science : a Publication of the Protein Society. 15: 1175-81. PMID 16641490 DOI: 10.1110/ps.062073506  1
2006 Lai RY, Lagally ET, Lee SH, Soh HT, Plaxco KW, Heeger AJ. Rapid, sequence-specific detection of unpurified PCR amplicons via a reusable, electrochemical sensor. Proceedings of the National Academy of Sciences of the United States of America. 103: 4017-21. PMID 16537478 DOI: 10.1073/pnas.0511325103  1
2006 Baker BR, Lai RY, Wood MS, Doctor EH, Heeger AJ, Plaxco KW. An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids. Journal of the American Chemical Society. 128: 3138-9. PMID 16522082 DOI: 10.1021/ja056957p  1
2006 de los Rios MA, Muralidhara BK, Wildes D, Sosnick TR, Marqusee S, Wittung-Stafshede P, Plaxco KW, Ruczinski I. On the precision of experimentally determined protein folding rates and phi-values. Protein Science : a Publication of the Protein Society. 15: 553-63. PMID 16501226 DOI: 10.1110/ps.051870506  1
2006 Lai RY, Lee SH, Soh HT, Plaxco KW, Heeger AJ. Differential labeling of closely spaced biosensor electrodes via electrochemical lithography. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 1932-6. PMID 16460130 DOI: 10.1021/la052132h  1
2006 Xu J, Plaxco KW, Allen SJ. Absorption spectra of liquid water and aqueous buffers between 0.3 and 3.72 THz. The Journal of Chemical Physics. 124: 036101. PMID 16438614 DOI: 10.1063/1.2151267  1
2006 Seferos DS, Lai RY, Plaxco KW, Bazan GC. a,ω-dithiol oligo(phenylene vinylene)s for the preparation of high-quality π-conjugated self-assembled monolayers and nanoparticle- functionalized electrodes Advanced Functional Materials. 16: 2387-2392. DOI: 10.1002/adfm.200500902  1
2005 Xiao Y, Piorek BD, Plaxco KW, Heeger AJ. A reagentless signal-on architecture for electronic, aptamer-based sensors via target-induced strand displacement. Journal of the American Chemical Society. 127: 17990-1. PMID 16366535 DOI: 10.1021/ja056555h  1
2005 de los Rios MA, Daneshi M, Plaxco KW. Experimental investigation of the frequency and substitution dependence of negative phi-values in two-state proteins. Biochemistry. 44: 12160-7. PMID 16142914 DOI: 10.1021/bi0505621  1
2005 McCarney ER, Kohn JE, Plaxco KW. Is there or isn't there? The case for (and against) residual structure in chemically denatured proteins. Critical Reviews in Biochemistry and Molecular Biology. 40: 181-9. PMID 16126485 DOI: 10.1080/10409230591008143  1
2005 McCarney ER, Werner JH, Bernstein SL, Ruczinski I, Makarov DE, Goodwin PM, Plaxco KW. Site-specific dimensions across a highly denatured protein; a single molecule study. Journal of Molecular Biology. 352: 672-82. PMID 16095607 DOI: 10.1016/j.jmb.2005.07.015  1
2005 Kohn JE, Plaxco KW. Engineering a signal transduction mechanism for protein-based biosensors. Proceedings of the National Academy of Sciences of the United States of America. 102: 10841-5. PMID 16046542 DOI: 10.1073/pnas.0503055102  1
2005 Xiao Y, Lubin AA, Heeger AJ, Plaxco KW. Label-free electronic detection of thrombin in blood serum by using an aptamer-based sensor. Angewandte Chemie (International Ed. in English). 44: 5456-9. PMID 16044476 DOI: 10.1002/anie.200500989  1
2005 Fan C, Plaxco KW, Heeger AJ. Biosensors based on binding-modulated donor-acceptor distances. Trends in Biotechnology. 23: 186-92. PMID 15780710 DOI: 10.1016/j.tibtech.2005.02.005  1
2005 Raleigh DP, Plaxco KW. The protein folding transition state: what are Phi-values really telling us? Protein and Peptide Letters. 12: 117-22. PMID 15723637 DOI: 10.2174/0929866053005809  1
2005 Maxwell KL, Wildes D, Zarrine-Afsar A, De Los Rios MA, Brown AG, Friel CT, Hedberg L, Horng JC, Bona D, Miller EJ, Vallée-Bélisle A, Main ER, Bemporad F, Qiu L, Teilum K, ... ... Plaxco KW, et al. Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Science : a Publication of the Protein Society. 14: 602-16. PMID 15689503 DOI: 10.1110/ps.041205405  1
2005 de Los Rios MA, Plaxco KW. Apparent Debye-Huckel electrostatic effects in the folding of a simple, single domain protein. Biochemistry. 44: 1243-50. PMID 15667218 DOI: 10.1021/bi048444l  1
2005 Sumner JJ, Plaxco KW, Meinhart CD, Soh H. Development of an electrochemical biosensor without a sandwich assay Proceedings of Spie - the International Society For Optical Engineering. 6007. DOI: 10.1117/12.630748  1
2004 Kohn JE, Millett IS, Jacob J, Zagrovic B, Dillon TM, Cingel N, Dothager RS, Seifert S, Thiyagarajan P, Sosnick TR, Hasan MZ, Pande VS, Ruczinski I, Doniach S, Plaxco KW. Random-coil behavior and the dimensions of chemically unfolded proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 12491-6. PMID 15314214 DOI: 10.1073/pnas.0403643101  1
2004 Gillespie B, Plaxco KW. Using protein folding rates to test protein folding theories. Annual Review of Biochemistry. 73: 837-59. PMID 15189160 DOI: 10.1146/annurev.biochem.73.011303.073904  1
2003 Xu J, Ramian GJ, Galan JF, Savvidis PG, Scopatz AM, Birge RR, Allen SJ, Plaxco KW. Terahertz circular dichroism spectroscopy: a potential approach to the in situ detection of life's metabolic and genetic machinery. Astrobiology. 3: 489-504. PMID 14678660 DOI: 10.1089/153110703322610609  1
2003 Ivankov DN, Garbuzynskiy SO, Alm E, Plaxco KW, Baker D, Finkelstein AV. Contact order revisited: influence of protein size on the folding rate. Protein Science : a Publication of the Protein Society. 12: 2057-62. PMID 12931003 DOI: 10.1110/ps.0302503  1
2003 Fan C, Plaxco KW, Heeger AJ. Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA. Proceedings of the National Academy of Sciences of the United States of America. 100: 9134-7. PMID 12867594 DOI: 10.1073/pnas.1633515100  1
2003 Gillespie B, Vu DM, Shah PS, Marshall SA, Dyer RB, Mayo SL, Plaxco KW. NMR and temperature-jump measurements of de novo designed proteins demonstrate rapid folding in the absence of explicit selection for kinetics. Journal of Molecular Biology. 330: 813-9. PMID 12850149  1
2003 Calloni G, Taddei N, Plaxco KW, Ramponi G, Stefani M, Chiti F. Comparison of the folding processes of distantly related proteins. Importance of hydrophobic content in folding. Journal of Molecular Biology. 330: 577-91. PMID 12842473 DOI: 10.1016/S0022-2836(03)00627-2  1
2003 Fan C, Wang S, Hong JW, Bazan GC, Plaxco KW, Heeger AJ. Beyond superquenching: hyper-efficient energy transfer from conjugated polymers to gold nanoparticles. Proceedings of the National Academy of Sciences of the United States of America. 100: 6297-301. PMID 12750470 DOI: 10.1073/pnas.1132025100  1
2003 Jewett AI, Pande VS, Plaxco KW. Cooperativity, smooth energy landscapes and the origins of topology-dependent protein folding rates. Journal of Molecular Biology. 326: 247-53. PMID 12547206 DOI: 10.1016/S0022-2836(02)01356-6  1
2003 Makarov DE, Plaxco KW. The topomer search model: A simple, quantitative theory of two-state protein folding kinetics. Protein Science : a Publication of the Protein Society. 12: 17-26. PMID 12493824 DOI: 10.1110/ps.0220003  1
2003 Fan C, Hirasa T, Plaxco KW, Heeger AJ. Photoluminescence quenching of water-soluble conjugated polymers by viologen derivatives: Effect of hydrophobicity Langmuir. 19: 3554-3556. DOI: 10.1021/la026651l  1
2002 Millett IS, Doniach S, Plaxco KW. Toward a taxonomy of the denatured state: small angle scattering studies of unfolded proteins. Advances in Protein Chemistry. 62: 241-62. PMID 12418105 DOI: 10.1016/S0065-3233(02)62009-1  1
2002 Thompson JB, Hansma HG, Hansma PK, Plaxco KW. The backbone conformational entropy of protein folding: experimental measures from atomic force microscopy. Journal of Molecular Biology. 322: 645-52. PMID 12225756 DOI: 10.1016/S0022-2836(02)00801-X  1
2002 Fan C, Plaxco KW, Heeger AJ. High-efficiency fluorescence quenching of conjugated polymers by proteins. Journal of the American Chemical Society. 124: 5642-3. PMID 12010029 DOI: 10.1021/ja025899u  1
2002 Makarov DE, Keller CA, Plaxco KW, Metiu H. How the folding rate constant of simple, single-domain proteins depends on the number of native contacts. Proceedings of the National Academy of Sciences of the United States of America. 99: 3535-9. PMID 11904417 DOI: 10.1073/pnas.052713599  1
2002 Larson SM, Ruczinski I, Davidson AR, Baker D, Plaxco KW. Residues participating in the protein folding nucleus do not exhibit preferential evolutionary conservation. Journal of Molecular Biology. 316: 225-33. PMID 11851333 DOI: 10.1006/jmbi.2001.5344  1
2002 Millet IS, Townsley LE, Chiti F, Doniach S, Plaxco KW. Equilibrium collapse and the kinetic 'foldability' of proteins. Biochemistry. 41: 321-5. PMID 11772031 DOI: 10.1021/bi015695a  1
2002 Fan C, Gillespie B, Wang G, Heeger AJ, Plaxco KW. Spectroscopy and electrochemistry of the covalent pyridine-cytochrome c complex and a pyridine-induced, "alkaline-like" conformation Journal of Physical Chemistry B. 106: 11375-11383. DOI: 10.1021/jp0261307  1
2001 Plaxco KW, Gross M. Unfolded, yes, but random? Never! Nature Structural Biology. 8: 659-60. PMID 11473247 DOI: 10.1038/90349  1
2000 Gillespie B, Plaxco KW. Nonglassy kinetics in the folding of a simple single-domain protein. Proceedings of the National Academy of Sciences of the United States of America. 97: 12014-9. PMID 11050233 DOI: 10.1073/pnas.97.22.12014  1
2000 Plaxco KW, Simons KT, Ruczinski I, Baker D. Topology, stability, sequence, and length: defining the determinants of two-state protein folding kinetics. Biochemistry. 39: 11177-83. PMID 10985762 DOI: 10.1021/bi000200n  1
2000 Plaxco KW, Larson S, Ruczinski I, Riddle DS, Thayer EC, Buchwitz B, Davidson AR, Baker D. Evolutionary conservation in protein folding kinetics. Journal of Molecular Biology. 298: 303-12. PMID 10764599 DOI: 10.1006/jmbi.1999.3663  1
1999 Plaxco KW, Millett IS, Segel DJ, Doniach S, Baker D. Chain collapse can occur concomitantly with the rate-limiting step in protein folding. Nature Structural Biology. 6: 554-6. PMID 10360359 DOI: 10.1038/9329  1
1999 Viani MB, Schäffer TE, Paloczi GT, Pietrasanta LI, Smith BL, Thompson JB, Richter M, Rief M, Gaub HE, Plaxco KW, Cleland AN, Hansma HG, Hansma PK. Fast imaging and fast force spectroscopy of single biopolymers with a new atomic force microscope designed for small cantilevers Review of Scientific Instruments. 70: 4300-4303.  1
1998 Plaxco KW, Baker D. Limited internal friction in the rate-limiting step of a two-state protein folding reaction. Proceedings of the National Academy of Sciences of the United States of America. 95: 13591-6. PMID 9811844 DOI: 10.1073/pnas.95.23.13591  1
1998 Guijarro JI, Morton CJ, Plaxco KW, Campbell ID, Dobson CM. Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy. Journal of Molecular Biology. 276: 657-67. PMID 9551103 DOI: 10.1006/jmbi.1997.1553  1
1998 Plaxco KW, Simons KT, Baker D. Contact order, transition state placement and the refolding rates of single domain proteins. Journal of Molecular Biology. 277: 985-94. PMID 9545386 DOI: 10.1006/jmbi.1998.1645  1
1998 Plaxco KW, Riddle DS, Grantcharova V, Baker D. Simplified proteins: minimalist solutions to the 'protein folding problem'. Current Opinion in Structural Biology. 8: 80-5. PMID 9519299 DOI: 10.1016/S0959-440X(98)80013-4  1
1998 Plaxco KW, Guijarro JI, Morton CJ, Pitkeathly M, Campbell ID, Dobson CM. The folding kinetics and thermodynamics of the Fyn-SH3 domain. Biochemistry. 37: 2529-37. PMID 9485402 DOI: 10.1021/bi972075u  1
1997 Plaxco KW, Morton CJ, Grimshaw SB, Jones JA, Pitkeathly M, Campbell ID, Dobson CM. The effects of guanidine hydrochloride on the 'random coil' conformations and NMR chemical shifts of the peptide series GGXGG. Journal of Biomolecular Nmr. 10: 221-30. PMID 20700831 DOI: 10.1023/A:1018340217891  1
1997 Plaxco KW, Spitzfaden C, Campbell ID, Dobson CM. A comparison of the folding kinetics and thermodynamics of two homologous fibronectin type III modules. Journal of Molecular Biology. 270: 763-70. PMID 9245603 DOI: 10.1006/jmbi.1997.1148  1
1997 Gross M, Plaxco KW. Protein engineering. Reading, writing and redesigning. Nature. 388: 419-20. PMID 9242395 DOI: 10.1038/41204  1
1997 O'Brien R, Wynn R, Driscoll PC, Davis B, Plaxco KW, Sturtevant JM, Ladbury JE. The adaptability of Escherichia coli thioredoxin to non-conservative amino acid substitutions. Protein Science : a Publication of the Protein Society. 6: 1325-32. PMID 9194193 DOI: 10.1002/pro.5560060621  1
1997 Plaxco KW, Gross M. Cell biology. The importance of being unfolded. Nature. 386: 657, 659. PMID 9109481 DOI: 10.1038/386657a0  1
1996 Plaxco KW, Dobson CM. Time-resolved biophysical methods in the study of protein folding. Current Opinion in Structural Biology. 6: 630-6. PMID 8913685 DOI: 10.1016/S0959-440X(96)80029-7  1
1996 Plaxco KW, Spitzfaden C, Campbell ID, Dobson CM. Rapid refolding of a proline-rich all-beta-sheet fibronectin type III module. Proceedings of the National Academy of Sciences of the United States of America. 93: 10703-6. PMID 8855243 DOI: 10.1073/pnas.93.20.10703  1
1994 Plaxco KW, Goddard WA. Contributions of the thymine methyl group to the specific recognition of poly- and mononucleotides: an analysis of the relative free energies of solvation of thymine and uracil. Biochemistry. 33: 3050-4. PMID 8130218  1
1989 Plaxco KW, Mathiowetz AM, Goddard WA. Predictions of structural elements for the binding of Hin recombinase with the hix site of DNA. Proceedings of the National Academy of Sciences of the United States of America. 86: 9841-5. PMID 2602378 DOI: 10.1073/pnas.86.24.9841  1
1985 Mason JR, Leong FC, Plaxco KW, Morton TH. Two-step covalent modification of proteins. Selective labeling of schiff base-forming sites and selective blockade of the sense of smell in vivo Journal of the American Chemical Society. 107: 6075-6084.  1
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