Hartmuth C. Kolb - Publications

Affiliations: 
Eli Lilly and Company, Indianapolis, IN, United States 
Area:
Click chemistry
Website:
http://de.wikipedia.org/wiki/Hartmuth_C._Kolb

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Year Citation  Score
2010 Kolb HC, Finn MG, Sharpless KB. ChemInform Abstract: Click Chemistry: Diverse Chemical Function from a Few Good Reactions Cheminform. 32: no-no. DOI: 10.1002/chin.200135279  0.442
2010 KOLB HC, ANDERSSON PG, SHARPLESS KB. ChemInform Abstract: Toward an Understanding of the High Enantioselectivity in the Osmium- Catalyzed Asymmetric Dihydroxylation (AD). Part 1. Kinetics. Cheminform. 25: no-no. DOI: 10.1002/chin.199426078  0.584
2010 KOLB HC, BENNANI YL, SHARPLESS KB. ChemInform Abstract: Short and Practical Syntheses of (R)-(-)-Carnitine and (R)-(-)-γ- Amino-β-hydroxybutyric Acid (GABOB). Cheminform. 24: no-no. DOI: 10.1002/chin.199321060  0.33
2010 KOLB HC, SHARPLESS KB. ChemInform Abstract: A Simplified Procedure for the Stereospecific Transformation of 1,2- Diols into Epoxides. Cheminform. 24: no-no. DOI: 10.1002/chin.199313174  0.35
2010 KOLB HC, LEY SV, SHEPPARD RN, SLAWIN AMZ, SMITH SC, WILLIAMS DJ, WOOD A. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 13. On the Use of the Intramolecular Diels-Alder Reaction for the Construction of trans-Fused Hydrobenzofuran Fragments for Azadirachtin Synthesis. Cheminform. 24: no-no. DOI: 10.1002/chin.199310283  0.421
2010 KOLB HC, LEY SV, SLAWIN AMZ, WILLIAMS DJ. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 12. Use of Silicon as a Control Element in the Synthesis of a Highly Functionalized Decalin Fragment of Azadirachtin. Cheminform. 24: no-no. DOI: 10.1002/chin.199310282  0.323
2010 LEY SV, ARMSTRONG A, DIEZ-MARTIN D, FORD MJ, GRICE P, KNIGHT JG, KOLB HC, MADIN A, MARBY CA, MUKHERJEE S, SHAW AN, SLAWIN AMZ, VILE S, WHITE AD, WILLIAMS DJ, et al. ChemInform Abstract: Total Synthesis of the Anthelmintic Macrolide Avermectin B1a. Cheminform. 22: no-no. DOI: 10.1002/chin.199128240  0.371
2008 Ley SV, Abad-Somovilla A, Anderson JC, Ayats C, Bänteli R, Beckmann E, Boyer A, Brasca MG, Brice A, Broughton HB, Burke BJ, Cleator E, Craig D, Denholm AA, Denton RM, ... ... Kolb HC, et al. The synthesis of azadirachtin: a potent insect antifeedant. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10683-704. PMID 18821532 DOI: 10.1002/Chem.200801103  0.73
2008 Ley S, Abad-Somovilla A, Anderson J, Ayats C, Bänteli R, Beckmann E, Boyer A, Brasca M, Brice A, Broughton H, Burke B, Cleator E, Craig D, Denholm A, Denton R, ... ... Kolb H, et al. Cover Picture: The Synthesis of Azadirachtin: A Potent Insect Antifeedant (Chem. Eur. J. 34/2008) Chemistry - a European Journal. 14: 10503-10503. DOI: 10.1002/Chem.200890139  0.705
2008 Finn MG, Kolb HC, Fokin VV, Sharpless KB. Click chemistry - Definition and aims Progress in Chemistry. 20: 1-4.  0.62
2006 Whiting M, Muldoon J, Lin YC, Silverman SM, Lindstrom W, Olson AJ, Kolb HC, Finn MG, Sharpless KB, Elder JH, Fokin VV. Inhibitors of HIV-1 protease by using in situ click chemistry. Angewandte Chemie (International Ed. in English). 45: 1435-9. PMID 16425339 DOI: 10.1002/Anie.200502161  0.702
2005 Radi? Z, Manetsch R, Krasi?ski A, Raushel J, Yamauchi J, Garcia C, Kolb H, Sharpless KB, Taylor P. Molecular basis of interactions of cholinesterases with tight binding inhibitors. Chemico-Biological Interactions. 157: 133-41. PMID 16289416 DOI: 10.1016/J.Cbi.2005.10.020  0.66
2005 Bourne Y, Radi? Z, Kolb HC, Sharpless KB, Taylor P, Marchot P. Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE. Chemico-Biological Interactions. 157: 159-65. PMID 16259971 DOI: 10.1016/J.Cbi.2005.10.018  0.39
2005 Krasi?ski A, Radi? Z, Manetsch R, Raushel J, Taylor P, Sharpless KB, Kolb HC. In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors. Journal of the American Chemical Society. 127: 6686-92. PMID 15869290 DOI: 10.1021/Ja043031T  0.688
2005 Narayan S, Muldoon J, Finn MG, Fokin VV, Kolb HC, Sharpless KB. "On water": unique reactivity of organic compounds in aqueous suspension. Angewandte Chemie (International Ed. in English). 44: 3275-9. PMID 15844112 DOI: 10.1002/Anie.200462883  0.637
2005 Narayan S, Muldoon J, Finn MG, Fokin VV, Kolb HC, Sharpless KB. Cover Picture: “On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension (Angew. Chem. Int. Ed. 21/2005) Angewandte Chemie International Edition. 44: 3157-3157. DOI: 10.1002/Anie.200590069  0.652
2005 Narayan S, Muldoon J, Finn MG, Fokin VV, Kolb HC, Sharpless KB. Titelbild: “On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension (Angew. Chem. 21/2005) Angewandte Chemie. 117: 3219-3219. DOI: 10.1002/Ange.200590069  0.648
2004 Mocharla VP, Colasson B, Lee LV, Röper S, Sharpless KB, Wong CH, Kolb HC. In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II. Angewandte Chemie (International Ed. in English). 44: 116-20. PMID 15599912 DOI: 10.1002/Anie.200461580  0.647
2004 Manetsch R, Krasi?ski A, Radi? Z, Raushel J, Taylor P, Sharpless KB, Kolb HC. In situ click chemistry: enzyme inhibitors made to their own specifications. Journal of the American Chemical Society. 126: 12809-18. PMID 15469276 DOI: 10.1021/Ja046382G  0.686
2004 Bourne Y, Kolb HC, Radi? Z, Sharpless KB, Taylor P, Marchot P. Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation. Proceedings of the National Academy of Sciences of the United States of America. 101: 1449-54. PMID 14757816 DOI: 10.1073/Pnas.0308206100  0.474
2003 Kolb HC, Sharpless KB. The growing impact of click chemistry on drug discovery. Drug Discovery Today. 8: 1128-37. PMID 14678739 DOI: 10.1016/S1359-6446(03)02933-7  0.445
2001 Kolb HC, Finn MG, Sharpless KB. Click Chemistry: Diverse Chemical Function from a Few Good Reactions. Angewandte Chemie (International Ed. in English). 40: 2004-2021. PMID 11433435 DOI: 10.1002/1521-3773(20010601)40:11<2004::Aid-Anie2004>3.3.Co;2-X  0.59
2001 Kolb HC, Finn MG, Sharpless KB. Click-Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen Angewandte Chemie. 113: 2056-2075. DOI: 10.1002/1521-3757(20010601)113:11<2056::Aid-Ange2056>3.0.Co;2-W  0.504
1997 Nelson DW, Gypser A, Ho PT, Kolb HC, Kondo T, Kwong HL, McGrath DV, Rubin AE, Norrby PO, Gable KP, Sharpless KB. Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation. 4. Electronic effects in amine-accelerated osmylations Journal of the American Chemical Society. 119: 1840-1858. DOI: 10.1021/Ja961464T  0.698
1994 Norrby PO, Kolb HC, Sharpless KB. Calculations on the reaction of ruthenium tetroxide with olefins using density functional theory (DFT). Implications for the possibility of intermediates in osmium-catalyzed asymmetric dihydroxylation Organometallics. 13: 344-347. DOI: 10.1021/Om00013A050  0.582
1994 Wang Z, Kolb HC, Sharpless KB. Large-Scale and Highly Enantioselective Synthesis of the Taxol C-13 Side Chain through Asymmetric Dihydroxylation The Journal of Organic Chemistry. 59: 5104-5105. DOI: 10.1021/Jo00096A072  0.41
1994 Norrby P, Kolb HC, Sharpless KB. Toward an Understanding of the High Enantioselectivity in the Osmium-Catalyzed Asymmetric Dihydroxylation. 2. A Qualitative Molecular Mechanics Approach Journal of the American Chemical Society. 116: 8470-8478. DOI: 10.1021/Ja00098A006  0.576
1994 Kolb HC, Andersson PG, Sharpless KB. Toward an Understanding of the High Enantioselectivity in the Osmium-Catalyzed Asymmetric Dihydroxylation (AD). 1. Kinetics Journal of the American Chemical Society. 116: 1278-1291. DOI: 10.1021/Ja00083A014  0.578
1994 Kolb HC, VanNieuwenhze MS, Sharpless KB. Catalytic Asymmetric Dihydroxylation Chemical Reviews. 94: 2483-2547. DOI: 10.1021/Cr00032A009  0.632
1994 Becker H, Tong Ho P, Kolb HC, Loren S, Norrby PO, Sharpless KB. Comparing two models for the selectivity in the asymmetric dihydroxylation reaction (AD) Tetrahedron Letters. 35: 7315-7318. DOI: 10.1016/0040-4039(94)85302-9  0.738
1994 Norrby PO, Kolb HC, Sharpless KB. Calculations on the reaction of ruthenium tetraoxide with olefins using density functional theory (DFT). Implications for the possibility of intermediates in the osmium-catalyzed asymmetric dihydroxylation (AD) Organometallics. 13: 344-347.  0.498
1994 Kolb HC, VanNieuwenhze MS, Sharpless KB. Catalytic asymmetric dihydroxylation Chemical Reviews. 94: 2483-2547.  0.568
1994 Norrby PO, Kolb HC, Sharpless KB. Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation. 2. A qualitative molecular mechanics approach Journal of the American Chemical Society. 116: 8470-8478.  0.481
1993 Kolb HC, Andersson PG, Bennani YL, Crispino GA, Jeong KS, Kwong HL, Sharpless KB. On "The origin of high enantioselectivity in the dihydroxylation of olefins using osmium tetraoxide and cinchona alkaloid catalysts" Journal of the American Chemical Society. 115: 12226-12227. DOI: 10.1021/Ja00078A096  0.543
1993 Kolb HC, Bennani YL, Sharpless KB. Short and practical syntheses of(R)-(-)-carnitine and (R)-(-)-γ-amino-β-hydroxybutyric acid (GABOB) Tetrahedron: Asymmetry. 4: 133-141. DOI: 10.1016/S0957-4166(00)86023-1  0.346
1992 Kolb HC, Ley SV, Sheppard RN, Slawin AMZ, Smith SC, Williams DJ, Wood A. Chemistry of insect antifeedants from azadirachta indica (Part 13): On the use of the intramolecular diels-alder reaction for the construction of trans-fused hydrobenzofuran fragments for azadirachtin synthesis Journal of the Chemical Society, Perkin Transactions 1. 2763-2777. DOI: 10.1039/P19920002763  0.495
1992 Kolb HC, Ley SV, Slawin AMZ, Williams DJ. Chemistry of insect antifeedants from azadirachta indica (Part 12): Use of silicon as a control element in the synthesis of a highly functionalized decalin fragment of azadirachtin Journal of the Chemical Society, Perkin Transactions 1. 2735-2762. DOI: 10.1039/P19920002735  0.523
1992 Kolb HC, Sharpless KB. A simplified procedure for the stereospecific transformation of 1,2-diols into epoxides Tetrahedron. 48: 10515-10530. DOI: 10.1016/S0040-4020(01)88349-6  0.446
1991 Ley SV, Armstrong A, Díez-Martín D, Ford MJ, Grice P, Knight JG, Kolb HC, Madin A, Marby CA, Mukherjee S, Shaw AN, Slawin AMZ, Vile S, White AD, Williams DJ, et al. Total synthesis of the anthelmintic macrolide avermectin B1a Journal of the Chemical Society-Perkin Transactions 1. 667-692. DOI: 10.1039/P19910000667  0.621
1991 Kolb HC, Ley SV. Chemistry of insect antifeedants from Azadirachta indica (Part 10): synthesis of a highly functionalised decalin fragment of azadirachtin Tetrahedron Letters. 32: 6187-6190. DOI: 10.1016/0040-4039(91)80785-5  0.489
1990 Díez-Martín D, Grice P, Kolb HC, Ley SV, Madin A. Total Synthesis of Avermectin B1a: Synthesis of the C11-C25 Spiroacetal Fragment Synlett. 1990: 326-328. DOI: 10.1055/S-1990-21079  0.441
1990 Diez-Martin D, Grice P, Kolb HC, Ley SV, Madin A. Synthesis of a C16-C28 spiroacetal fragment of avermectin B1a and reassignment of some 1H and 13C resonances of avermectin B1a Tetrahedron Letters. 31: 3445-3448. DOI: 10.1016/S0040-4039(00)97418-5  0.4
Low-probability matches (unlikely to be authored by this person)
2010 NORCROSS RD, VON MATT P, KOLB HC, BELLUS D. ChemInform Abstract: Synthesis and Reactivity of Compounds with Cyclobutane Ring(s). Part 20. Synthesis of Novel Cyclobutylphosphonic Acids as Inhibitors of Imidazole Glycerol Phosphate Dehydratase. Cheminform. 28: no-no. DOI: 10.1002/chin.199751184  0.256
2010 Walsh JC, Kolb HC. Applications of click chemistry in radiopharmaceutical development. Chimia. 64: 29-33. PMID 21137680 DOI: 10.2533/chimia.2010.29  0.233
2002 Katritzky AR, Zhang S, Wang M, Kolb HC, Steel PJ. Novel syntheses of polysubstituted pyrroles and oxazoles by 1,3-dipolar cycloaddition reactions of benzotriazole-stabilized nitrile ylides Journal of Heterocyclic Chemistry. 39: 759-765.  0.225
1994 Kolb HC, Andersson PG, Sharpless KB. Toward an understanding of the high enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD). 1. Kinetics Journal of the American Chemical Society. 116: 1278-1291.  0.214
1991 Ley SV, Armstrong A, Díez-Martín D, Ford MJ, Grice P, Knight JG, Kolb HC, Madin A, Marby CA, Mukherjee S, Shaw AN, Slawin AMZ, Vile S, White AD, Williams DJ, et al. Total synthesis of the anthelmintic macrolide avermectin B1a Journal of the Chemical Society, Perkin Transactions 1. 667-692.  0.193
2000 Katritzky AR, Huang TB, Voronkov MV, Wang M, Kolb H. Efficient one-pot synthesis of polysubstituted pyrroles Journal of Organic Chemistry. 65: 8819-8821. PMID 11112611 DOI: 10.1021/Jo001160W  0.192
1997 Norcross RD, Von Matt P, Kolb HC, Belluš D. Synthesis of novel cyclobutylphosphonic acids as inhibitors of imidazole glycerol phosphate dehydratase Tetrahedron. 53: 10289-10312. DOI: 10.1016/S0040-4020(97)00682-0  0.189
2010 WANG Z, KOLB HC, SHARPLESS KB. ChemInform Abstract: Large-Scale and Highly Enantioselective Synthesis of the Taxol C-13 Side Chain (VII) Through Asymmetric Dihydroxylation. Cheminform. 26: no-no. DOI: 10.1002/chin.199511220  0.183
1994 Wang ZM, Kolb HC, Sharpless KB. Large-scale and highly enantioselective synthesis of the taxol C-13 side chain through asymmetric dihydroxylation Journal of Organic Chemistry. 59: 5104-5105.  0.173
2010 Elizarov AM, van Dam RM, Shin YS, Kolb HC, Padgett HC, Stout D, Shu J, Huang J, Daridon A, Heath JR. Design and optimization of coin-shaped microreactor chips for PET radiopharmaceutical synthesis. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 282-7. PMID 20124050 DOI: 10.2967/Jnumed.109.065946  0.166
2009 Wang Y, Lin WY, Liu K, Lin RJ, Selke M, Kolb HC, Zhang N, Zhao XZ, Phelps ME, Shen CK, Faull KF, Tseng HR. An integrated microfluidic device for large-scale in situ click chemistry screening. Lab On a Chip. 9: 2281-5. PMID 19636457 DOI: 10.1039/B907430A  0.156
1993 Crispino GA, Jeong KS, Kolb HC, Wang ZM, Xu D, Barry Sharpless K. Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands Journal of Organic Chemistry. 58: 3785-3786.  0.149
1993 Kolb HC, Andersson PG, Bennani YL, Crispino GA, Jeong KS, Kwong HL, Sharpless KB. On "the origin of high enantioselectivity in the dihydroxylation of olefins using osmium tetraoxide and cinchona alkaloid catalysts" Journal of the American Chemical Society. 115: 12226-12227.  0.146
2010 Zhang J, Elizarov A, Miraghaie R, Ball E, Kolb H. A system for the radiochemical purification of microfluidics-generated compound Journal of Labelled Compounds and Radiopharmaceuticals. 53: 311-314. DOI: 10.1002/jlcr.1768  0.145
2013 Hugenberg V, Riemann B, Hermann S, Schober O, Schäfers M, Szardenings K, Lebedev A, Gangadharmath U, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation. Journal of Medicinal Chemistry. 56: 6858-70. PMID 23899323 DOI: 10.1021/jm4006753  0.145
2013 Mirfeizi L, Walsh J, Kolb H, Campbell-Verduyn L, Dierckx RA, Feringa BL, Elsinga PH, de Groot T, Sannen I, Bormans G, Celen S. Synthesis of [18F]RGD-K5 by catalyzed [3 + 2] cycloaddition for imaging integrin αvβ3 expression in vivo. Nuclear Medicine and Biology. 40: 710-6. PMID 23706550 DOI: 10.1016/J.Nucmedbio.2013.04.003  0.139
1997 Hanessian S, Reddy GV, Huynh HK, Jingwen P, Pedatella S, Ernst B, Kolb HC. Design and synthesis of sialyl Le(x) mimetics based on carbocyclic scaffolds derived from (-)-quinic acid Bioorganic and Medicinal Chemistry Letters. 7: 2729-2734. DOI: 10.1016/S0960-894X(97)10077-4  0.129
2005 Lee CC, Sui G, Elizarov A, Shu CJ, Shin YS, Dooley AN, Huang J, Daridon A, Wyatt P, Stout D, Kolb HC, Witte ON, Satyamurthy N, Heath JR, Phelps ME, et al. Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics. Science (New York, N.Y.). 310: 1793-6. PMID 16357255 DOI: 10.1126/Science.1118919  0.128
2018 Hugenberg V, Behrends M, Wagner S, Hermann S, Schäfers M, Kolb HC, Szardenings K, Walsh JC, Gomez LF, Kopka K, Haufe G. Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid. Ejnmmi Radiopharmacy and Chemistry. 3: 10. PMID 30101186 DOI: 10.1186/s41181-018-0045-0  0.116
2012 Yokell DL, Leece AK, Lebedev A, Miraghaie R, Ball CE, Zhang J, Kolb H, Elizarov A, Mahmood U. Microfluidic single vessel production of hypoxia tracer 1H-1-(3-[18F]-fluoro-2-hydroxy-propyl)-2-nitro-imidazole ([18F]-FMISO). Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 70: 2313-6. PMID 22871433 DOI: 10.1016/j.apradiso.2012.05.022  0.113
1997 Kolb HC. Design and synthesis of a macrocyclic E-selectin antagonist Bioorganic and Medicinal Chemistry Letters. 7: 2629-2634. DOI: 10.1016/S0960-894X(97)10041-5  0.112
2003 Schwardt O, Kolb H, Ernst B. Drug discovery today Current Topics in Medicinal Chemistry. 3: 1-9. PMID 12570684 DOI: 10.2174/1567204052931050  0.109
1990 Kolb HC, Martin H, Hoffmann R. A total synthesis of racemic and optically active terrein (trans-4,5-dihydroxy-3-[(E)-1-propenyl]-2-cyclopenten-1-one) Tetrahedron: Asymmetry. 1: 237-250. DOI: 10.1016/S0957-4166(00)86329-6  0.108
2004 Voronkov MV, Gontcharov AV, Wang ZM, Richardson PF, Kolb HC. Efficient solution phase parallel synthesis of norstatine analogs Tetrahedron. 60: 9043-9048. DOI: 10.1016/j.tet.2004.07.085  0.106
2001 Ernst B, Dragic Z, Marti S, Müller C, Wagner B, Jahnke W, Magnani JL, Norman KE, Oehrlein R, Peters T, Kolb HC. Design and synthesis of E-selectin antagonists Chimia. 55: 268-274.  0.102
2011 Bejot R, Elizarov AM, Ball E, Zhang J, Miraghaie R, Kolb HC, Gouverneur V. Batch-mode microfluidic radiosynthesis of N-succinimidyl-4-[ 18F]fluorobenzoate for protein labelling Journal of Labelled Compounds and Radiopharmaceuticals. 54: 117-122. DOI: 10.1002/Jlcr.1826  0.102
2006 Elizarov AM, Kolb HC, Van Dam RM, Heath JR, Padgett HC, Huang J, Daridon A. Coin-shaped reactor in microfluidic devices used for radiopharmaceutical synthesis 2006 Nsti Nanotechnology Conference and Trade Show - Nsti Nanotech 2006 Technical Proceedings. 2: 542-545.  0.1
2012 Hugenberg V, Breyholz HJ, Riemann B, Hermann S, Schober O, Schäfers M, Gangadharmath U, Mocharla V, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. Journal of Medicinal Chemistry. 55: 4714-27. PMID 22540974 DOI: 10.1021/jm300199g  0.095
2012 Zhang W, Arteaga J, Cashion DK, Chen G, Gangadharmath U, Gomez LF, Kasi D, Lam C, Liang Q, Liu C, Mocharla VP, Mu F, Sinha A, Szardenings AK, Wang E, ... ... Kolb HC, et al. A highly selective and specific PET tracer for imaging of tau pathologies. Journal of Alzheimer's Disease : Jad. 31: 601-12. PMID 22683529 DOI: 10.3233/Jad-2012-120712  0.092
1990 Kolb HC, Hoffmann HMR. A ring contraction of 6-alkoxy-2,3-dihydro-6h-pyran-3-ones to polyfunctionalized cyclopentenones Tetrahedron. 46: 5127-5144. DOI: 10.1016/S0040-4020(01)87820-0  0.087
2001 Voronkov MV, Gontcharov AV, Wang ZM, Kolb HC. Reaction of α,β-dihydroxydihydrocinnamic esters with acetonitrile: A new approach to β-amino-α-hydroxydihydrocinnamic acids Arkivoc. 2001: 160-165.  0.085
2011 Elizarov AM, Meinhart C, Miraghaie R, van Dam RM, Huang J, Daridon A, Heath JR, Kolb HC. Flow optimization study of a batch microfluidics PET tracer synthesizing device. Biomedical Microdevices. 13: 231-42. PMID 21072595 DOI: 10.1007/S10544-010-9488-0  0.082
2023 Brum WS, Cullen NC, Janelidze S, Ashton NJ, Zimmer ER, Therriault J, Benedet AL, Rahmouni N, Tissot C, Stevenson J, Servaes S, Triana-Baltzer G, Kolb HC, Palmqvist S, Stomrud E, et al. A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases. Nature Aging. PMID 37653254 DOI: 10.1038/s43587-023-00471-5  0.081
2020 Schmidt ME, Janssens L, Moechars D, Rombouts FJR, Timmers M, Barret O, Constantinescu CC, Madonia J, Russell DS, Sandiego CM, Kolb H. Clinical evaluation of [F] JNJ-64326067, a novel candidate PET tracer for the detection of tau pathology in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32535652 DOI: 10.1007/S00259-020-04880-1  0.081
2004 Voronkov MV, Gontcharov AV, Wang Z, Richardson PF, Kolb HC. Erratum to “Efficient solution phase parallel synthesis of norstatine analogs” [Tetrahedron 60 (2004) 9043] Tetrahedron. 60: 12269. DOI: 10.1016/j.tet.2004.10.045  0.081
2006 Wang J, Sui G, Mocharla VP, Lin RJ, Phelps ME, Kolb HC, Tseng HR. Integrated microfluidics for parallel screening of an in situ click chemistry library. Angewandte Chemie (International Ed. in English). 45: 5276-81. PMID 16927322 DOI: 10.1002/Anie.200601677  0.078
2023 Sanchez-Rodriguez LM, Bezgin G, Carbonell F, Therriault J, Fernandez-Arias J, Servaes S, Rahmouni N, Tissot C, Stevenson J, Karikari TK, Ashton NJ, Benedet AL, Zetterberg H, Blennow K, Triana-Baltzer G, ... Kolb HC, et al. Revealing the combined roles of Aβ and tau in Alzheimer's disease via a pathophysiological activity decoder. Biorxiv : the Preprint Server For Biology. PMID 37502947 DOI: 10.1101/2023.02.21.529377  0.072
2007 Van Dam RM, Elizarov AM, Ball CE, Shen CKF, Padgett H, Kolb H, Rolland J, Diener L, Williams D, Edgecombe B, Jeffries J, Stoianova D, Stephen T, Motamedi F, Heath JR. Automated microfluidic-chip-based stand-alone instrument for the synthesis of radiopharmaceuticals on human-dose scales 2007 Nsti Nanotechnology Conference and Trade Show - Nsti Nanotech 2007, Technical Proceedings. 3: 300-303.  0.071
2021 Baker SL, Provost K, Thomas W, Whitman AJ, Janabi M, Schmidt ME, Timmers M, Kolb HC, Rabinovici GD, Jagust WJ. Evaluation of [F]-JNJ-64326067-AAA tau PET tracer in humans. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211031035. PMID 34259071 DOI: 10.1177/0271678X211031035  0.071
2004 Bourne Y, Kolb HC, Radic Z, Sharpless B, Taylor P, Marchot P. Click chemistry: an original approach for drug discovery Acta Crystallographica Section a Foundations of Crystallography. 60: s23-s23. DOI: 10.1107/S0108767304099568  0.07
2015 Ariza M, Kolb HC, Moechars D, Rombouts F, Andrés JI. Tau Positron Emission Tomography (PET) Imaging: Past, Present, and Future. Journal of Medicinal Chemistry. 58: 4365-82. PMID 25671691 DOI: 10.1021/jm5017544  0.069
2019 Rombouts FJR, Declercq L, Andrés JI, Bottelbergs A, Chen L, Iturrino L, Leenaerts JE, Mariën J, Song F, Wintmolders C, Wuyts SL, Xia C, Te Riele P, Bormans GM, Vandenberghe R, ... Kolb H, et al. Discovery of N-(4-[18F]fluoro-5-methylpyridin-2-yl)isoquinolin-6-amine (JNJ-64326067), a new promising tau positron emission tomography (PET) imaging tracer. Journal of Medicinal Chemistry. PMID 30810314 DOI: 10.1021/Acs.Jmedchem.8B01759  0.069
2023 Bellaver B, Povala G, Ferreira PCL, Ferrari-Souza JP, Leffa DT, Lussier FZ, Benedet AL, Ashton NJ, Triana-Baltzer G, Kolb HC, Tissot C, Therriault J, Servaes S, Stevenson J, Rahmouni N, et al. Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease. Nature Medicine. PMID 37248300 DOI: 10.1038/s41591-023-02380-x  0.068
1998 Hanessian S, Huynh HK, Reddy GV, McNaughton-Smith G, Ernst B, Kolb HC, Magnani J, Sweeley C. Exploration of beta-turn scaffolding motifs as components of sialyl Le(X) mimetics and their relevance to P-selectin. Bioorganic & Medicinal Chemistry Letters. 8: 2803-8. PMID 9873626 DOI: 10.1016/S0960-894X(98)00500-9  0.068
2010 Bejot R, Kersemans V, Kelly C, Carroll L, King RC, Gouverneur V, Elizarov AM, Ball C, Zhang J, Miraghaie R, Kolb HC, Smart S, Hill S. Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET. Nuclear Medicine and Biology. 37: 565-75. PMID 20610161 DOI: 10.1016/J.Nucmedbio.2010.03.011  0.068
2013 Su H, Chen G, Gangadharmath U, Gomez LF, Liang Q, Mu F, Mocharla VP, Szardenings AK, Walsh JC, Xia CF, Yu C, Kolb HC. Evaluation of [(18)F]-CP18 as a PET imaging tracer for apoptosis. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 15: 739-47. PMID 23681757 DOI: 10.1007/s11307-013-0644-9  0.067
2020 Triana-Baltzer G, Van Kolen K, Theunis C, Moughadam S, Slemmon R, Mercken M, Galpern W, Sun H, Kolb H. Development and Validation of a High Sensitivity Assay for Measuring p217 + tau in Cerebrospinal Fluid. Journal of Alzheimer's Disease : Jad. PMID 32831201 DOI: 10.3233/JAD-200463  0.066
2016 Hugenberg V, Hermann S, Galla F, Schäfers M, Wünsch B, Kolb HC, Szardenings K, Lebedev A, Walsh JC, Mocharla VP, Gangadharmath UB, Kopka K, Wagner S. Radiolabeled hydroxamate-based matrix metalloproteinase inhibitors: How chemical modifications affect pharmacokinetics and metabolic stability. Nuclear Medicine and Biology. 43: 424-437. PMID 27179748 DOI: 10.1016/j.nucmedbio.2016.03.005  0.065
2016 Kolb HC, Andrés JI. Tau Positron Emission Tomography Imaging. Cold Spring Harbor Perspectives in Biology. PMID 27940517 DOI: 10.1101/cshperspect.a023721  0.065
2013 Mocharla VP, Walsh JC, Padgett HC, Su H, Fueger B, Weber WA, Czernin J, Kolb HC. From in situ to in vivo: an in situ click-chemistry-derived carbonic anhydrase II imaging agent for positron emission tomography. Chemmedchem. 8: 43-8. PMID 23208787 DOI: 10.1002/Cmdc.201200466  0.064
2020 Simoes S, Neufeld JL, Triana-Baltzer G, Moughadam S, Chen EI, Kothiya M, Qureshi YH, Patel V, Honig LS, Kolb H, Small SA. Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans. Science Translational Medicine. 12. PMID 33239387 DOI: 10.1126/scitranslmed.aba6334  0.064
2013 Lebedev A, Miraghaie R, Kotta K, Ball CE, Zhang J, Buchsbaum MS, Kolb HC, Elizarov A. Batch-reactor microfluidic device: first human use of a microfluidically produced PET radiotracer. Lab On a Chip. 13: 136-45. PMID 23135409 DOI: 10.1039/c2lc40853h  0.064
2021 Shi L, Winchester LM, Westwood S, Baird AL, Anand SN, Buckley NJ, Hye A, Ashton NJ, Bos I, Vos SJB, Kate MT, Scheltens P, Teunissen CE, Vandenberghe R, Gabel S, ... ... Kolb HC, et al. Replication study of plasma proteins relating to Alzheimer's pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33792144 DOI: 10.1002/alz.12322  0.058
2015 Su H, Gorodny N, Gomez LF, Gangadharmath U, Mu F, Chen G, Walsh JC, Szardenings K, Kolb HC, Tamarappoo B. Noninvasive molecular imaging of apoptosis in a mouse model of anthracycline-induced cardiotoxicity. Circulation. Cardiovascular Imaging. 8: e001952. PMID 25657296 DOI: 10.1161/CIRCIMAGING.114.001952  0.057
2022 Groot C, Cicognola C, Bali D, Triana-Baltzer G, Dage JL, Pontecorvo MJ, Kolb HC, Osssenkoppele R, Janelidze S, Hansson O. Diagnostic and prognostic performance to detect Alzheimer's disease and clinical progression of a novel assay for plasma p-tau217. Alzheimer's Research & Therapy. 14: 67. PMID 35568889 DOI: 10.1186/s13195-022-01005-8  0.057
2018 Knopman DS, Haeberlein SB, Carrillo MC, Hendrix JA, Kerchner G, Margolin R, Maruff P, Miller DS, Tong G, Tome MB, Murray ME, Nelson PT, Sano M, Mattsson N, Sultzer DL, ... ... Kolb H, et al. The National Institute on Aging and the Alzheimer's Association Research Framework for Alzheimer's disease: Perspectives from the Research Roundtable. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 14: 563-575. PMID 29653607 DOI: 10.1016/J.Jalz.2018.03.002  0.055
2010 Dubois L, Lieuwes N, Secrest J, Supuran C, Wouters B, Kolb H, Lambin P. 66 poster: Imaging Hypoxia Response Using Fluorescent and Fluorine-18 Labeled Sulfonamide Inhibitors of CA IX Radiotherapy and Oncology. 94: S27. DOI: 10.1016/S0167-8140(15)34485-6  0.053
1997 Jahnke W, Kolb HC, Blommers MJJ, Magnani JL, Ernst B. Comparison of the bioactive conformations of sialyl Lewis(x) and a potent sialyl Lewis(x) mimic Angewandte Chemie - International Edition in English. 36: 2603-2607.  0.052
2022 Zicha S, Bateman RJ, Shaw LM, Zetterberg H, Bannon AW, Horton WA, Baratta M, Kolb HC, Dobler I, Mordashova Y, Saad ZS, Raunig DL, Spanakis EM, Li Y, Schindler SE, et al. Comparative analytical performance of multiple plasma Aβ42 and Aβ40 assays and their ability to predict positron emission tomography amyloid positivity. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35820077 DOI: 10.1002/alz.12697  0.052
2013 Xia CF, Arteaga J, Chen G, Gangadharmath U, Gomez LF, Kasi D, Lam C, Liang Q, Liu C, Mocharla VP, Mu F, Sinha A, Su H, Szardenings AK, Walsh JC, ... ... Kolb HC, et al. [(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 666-76. PMID 23411393 DOI: 10.1016/J.Jalz.2012.11.008  0.051
2018 Koole M, Schmidt M, Hijzen A, Ravenstijn P, Vandermeulen C, Van Weehaeghe D, Serdons K, Celen S, Bormans G, Ceusters M, Zhang W, Van Nueten L, Kolb H, de Hoon J, Van Laere K. F-JNJ-64413739, a novel PET ligand for the P2X7 ion channel: radiation dosimetry, kinetic modeling, test-retest variability and occupancy of the P2X7 antagonist JNJ-54175446. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30262518 DOI: 10.2967/Jnumed.118.216747  0.051
1997 Kolb HC, Ernst B. Recent progress in the glycodrug area Pure and Applied Chemistry. 69: 1879-1884.  0.05
2014 Su H, Gorodny N, Gomez LF, Gangadharmath UB, Mu F, Chen G, Walsh JC, Szardenings K, Berman DS, Kolb HC, Tamarappoo BK. Atherosclerotic plaque uptake of a novel integrin tracer ¹⁸F-Flotegatide in a mouse model of atherosclerosis. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 21: 553-62. PMID 24627345 DOI: 10.1007/s12350-014-9879-3  0.05
2023 Ferrari-Souza JP, Bellaver B, Ferreira PCL, Benedet AL, Povala G, Lussier FZ, Leffa DT, Therriault J, Tissot C, Soares C, Wang YT, Chamoun M, Servaes S, Macedo AC, Vermeiren M, ... ... Kolb HC, et al. APOEε4 potentiates amyloid β effects on longitudinal tau pathology. Nature Aging. PMID 37749258 DOI: 10.1038/s43587-023-00490-2  0.048
2020 Rombouts FJR, Declercq L, Andrés JI, Bottelbergs A, Chen L, Iturrino L, Leenaerts JE, Mariën J, Song F, Wintmolders C, Wuyts S, Xia CA, Te Riele P, Bormans G, Vandenberghe R, ... Kolb H, et al. Correction to Discovery of -(4-[F]Fluoro-5-methylpyridin-2-yl)isoquinolin-6-amine (JNJ-64326067), a New Promising Tau Positron Emission Tomography Imaging Tracer. Journal of Medicinal Chemistry. PMID 32069047 DOI: 10.1021/acs.jmedchem.0c00140  0.047
2018 Richards EM, Zanotti-Fregonara P, Fujita M, Newman L, Farmer C, Ballard ED, Machado-Vieira R, Yuan P, Niciu MJ, Lyoo CH, Henter ID, Salvadore G, Drevets WC, Kolb H, Innis RB, et al. PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects. Ejnmmi Research. 8: 57. PMID 29971587 DOI: 10.1186/S13550-018-0401-9  0.045
2018 Leinonen V, Rauramaa T, Johansson J, Bottelbergs A, Tesseur I, van der Ark P, Pemberton D, Koivisto AM, Jääskeläinen JE, Hiltunen M, Herukka SK, Blennow K, Zetterberg H, Jokinen P, Rokka J, ... ... Kolb HC, et al. S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies. Journal of Alzheimer's Disease : Jad. PMID 29865068 DOI: 10.3233/JAD-180071  0.044
2021 Triana-Baltzer G, Moughadam S, Slemmon R, Van Kolen K, Theunis C, Mercken M, Kolb HC. Development and validation of a high-sensitivity assay for measuring p217+tau in plasma. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12204. PMID 34095436 DOI: 10.1002/dad2.12204  0.044
2019 Berdyyeva T, Xia C, Taylor N, He Y, Chen G, Huang C, Zhang W, Kolb H, Letavic M, Bhattacharya A, Szardenings AK. PET Imaging of the P2X7 Ion Channel with a Novel Tracer [F]JNJ-64413739 in a Rat Model of Neuroinflammation. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 30632003 DOI: 10.1007/s11307-018-01313-2  0.043
2021 Sperling R, Henley D, Aisen PS, Raman R, Donohue MC, Ernstrom K, Rafii MS, Streffer J, Shi Y, Karcher K, Raghavan N, Tymofyeyev Y, Bogert J, Brashear HR, Novak G, ... ... Kolb H, et al. Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial. Jama Neurology. PMID 33464300 DOI: 10.1001/jamaneurol.2020.4857  0.043
1997 Jahnke W, Kolb HC, Blommers MJJ, Ernst B, Magnani JL. Vergleich der bioaktiven Konformationen von Sialyl-LewisX und einem potenten Sialyl-LewisX-Mimetikum Angewandte Chemie. 109: 2715-2719. DOI: 10.1002/Ange.19971092310  0.042
2013 Doss M, Kolb HC, Walsh JC, Mocharla V, Fan H, Chaudhary A, Zhu Z, Alpaugh RK, Lango MN, Yu JQ. Biodistribution and radiation dosimetry of 18F-CP-18, a potential apoptosis imaging agent, as determined from PET/CT scans in healthy volunteers. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 2087-92. PMID 24136934 DOI: 10.2967/jnumed.113.119800  0.042
2023 Therriault J, Servaes S, Tissot C, Rahmouni N, Ashton NJ, Benedet AL, Karikari TK, Macedo AC, Lussier FZ, Stevenson J, Wang YT, Fernandez-Arias J, Stevenson A, Socualaya KQ, Haeger A, ... ... Kolb HC, et al. Equivalence of plasma p-tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37078495 DOI: 10.1002/alz.13026  0.04
2012 Doss M, Kolb HC, Zhang JJ, Bélanger MJ, Stubbs JB, Stabin MG, Hostetler ED, Alpaugh RK, von Mehren M, Walsh JC, Haka M, Mocharla VP, Yu JQ. Biodistribution and radiation dosimetry of the integrin marker 18F-RGD-K5 determined from whole-body PET/CT in monkeys and humans. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 787-95. PMID 22499613 DOI: 10.2967/Jnumed.111.088955  0.039
2015 Schubert CR, O'Donnell P, Quan J, Wendland JR, Xi HS, Winslow AR, Domenici E, Essioux L, Kam-Thong T, Airey DC, Calley JN, Collier DA, Wang H, Eastwood B, Ebert P, ... ... Kolb H, et al. BrainSeq: Neurogenomics to Drive Novel Target Discovery for Neuropsychiatric Disorders Neuron. 88: 1078-1083. DOI: 10.1016/J.Neuron.2015.10.047  0.039
2019 Kolb H, Barret O, Bhattacharya A, Chen G, Constantinescu C, Huang C, Letavic M, Tamagnan G, Xia C, Zhang W, Szardenings AK. Preclinical evaluation and non-human primate receptor occupancy study of F-JNJ-64413739, a novel PET radioligand for P2X7 receptors. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30733317 DOI: 10.2967/Jnumed.118.212696  0.036
2022 Groot C, Cicognola C, Bali D, Triana-Baltzer G, Dage JL, Pontecorvo MJ, Kolb HC, Ossenkoppele R, Janelidze S, Hansson O. Correction: Diagnostic and prognostic performance to detect Alzheimer's disease and clinical progression of a novel assay for plasma p-tau217. Alzheimer's Research & Therapy. 14: 82. PMID 35698175 DOI: 10.1186/s13195-022-01023-6  0.036
2022 Janelidze S, Bali D, Ashton NJ, Barthélemy NR, Vanbrabant J, Stoops E, Vanmechelen E, He Y, Dolado AO, Triana-Baltzer G, Pontecorvo MJ, Zetterberg H, Kolb H, Vandijck M, Blennow K, et al. Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease. Brain : a Journal of Neurology. PMID 36087307 DOI: 10.1093/brain/awac333  0.035
2014 Chien DT, Szardenings AK, Bahri S, Walsh JC, Mu F, Xia C, Shankle WR, Lerner AJ, Su MY, Elizarov A, Kolb HC. Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808. Journal of Alzheimer's Disease : Jad. 38: 171-84. PMID 23948934 DOI: 10.3233/JAD-130098  0.035
2013 Xia CF, Chen G, Gangadharmath U, Gomez LF, Liang Q, Mu F, Mocharla VP, Su H, Szardenings AK, Walsh JC, Zhao T, Kolb HC. In vitro and in vivo evaluation of the caspase-3 substrate-based radiotracer [(18)F]-CP18 for PET imaging of apoptosis in tumors. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 15: 748-57. PMID 23689985 DOI: 10.1007/s11307-013-0646-7  0.034
1997 Kolb HC, Ernst B. Development of tools for the design of selectin antagonists Chemistry - a European Journal. 3: 1571-1578.  0.033
2024 Sexton CE, Bitan G, Bowles KR, Brys M, Buée L, Maina MB, Clelland CD, Cohen AD, Crary JF, Dage JL, Diaz K, Frost B, Gan L, Goate AM, Golbe LI, ... ... Kolb HC, et al. Novel avenues of tau research. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38170841 DOI: 10.1002/alz.13533  0.032
2020 Janelidze S, Stomrud E, Smith R, Palmqvist S, Mattsson N, Airey DC, Proctor NK, Chai X, Shcherbinin S, Sims JR, Triana-Baltzer G, Theunis C, Slemmon R, Mercken M, Kolb H, et al. Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease. Nature Communications. 11: 1683. PMID 32246036 DOI: 10.1038/s41467-020-15436-0  0.032
2023 Woo MS, Tissot C, Lantero-Rodriguez J, Snellman A, Therriault J, Rahmouni N, Macedo AC, Servaes S, Wang YT, Arias JF, Hosseini SA, Chamoun M, Lussier FZ, Benedet AL, Ashton NJ, ... ... Kolb HC, et al. Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-β positive individuals. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37920945 DOI: 10.1002/alz.13528  0.031
2020 Saad Z, Hibar D, Fedgchin M, Popova V, Furey ML, Singh J, Kolb H, Drevets WC, Chen G. Effects of Mu-Opiate Receptor Gene Polymorphism rs1799971 (A118G) on the Antidepressant and Dissociation Responses in Esketamine Nasal Spray Clinical Trials. The International Journal of Neuropsychopharmacology. PMID 32367114 DOI: 10.1093/Ijnp/Pyaa030  0.031
2013 Chien DT, Bahri S, Szardenings AK, Walsh JC, Mu F, Su MY, Shankle WR, Elizarov A, Kolb HC. Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807. Journal of Alzheimer's Disease : Jad. 34: 457-68. PMID 23234879 DOI: 10.3233/JAD-122059  0.031
2014 Doss M, Kolb HC, Walsh JC, Mocharla VP, Zhu Z, Haka M, Alpaugh RK, Chen DY, Yu JQ. Biodistribution and radiation dosimetry of the carbonic anhydrase IX imaging agent [(18) F]VM4-037 determined from PET/CT scans in healthy volunteers. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 739-46. PMID 24696183 DOI: 10.1007/s11307-014-0730-7  0.03
2023 Ferreira PCL, Therriault J, Tissot C, Ferrari-Souza JP, Benedet AL, Povala G, Bellaver B, Leffa DT, Brum WS, Lussier FZ, Bezgin G, Servaes S, Vermeiren M, Macedo AC, Cabrera A, ... ... Kolb H, et al. Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37534889 DOI: 10.1002/alz.13393  0.029
2022 Therriault J, Vermeiren M, Servaes S, Tissot C, Ashton NJ, Benedet AL, Karikari TK, Lantero-Rodriguez J, Brum WS, Lussier FZ, Bezgin G, Stevenson J, Rahmouni N, Kunach P, Wang YT, ... ... Kolb HC, et al. Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography. Jama Neurology. PMID 36508198 DOI: 10.1001/jamaneurol.2022.4485  0.029
2011 Dubois LJ, Lieuwes NG, Janssen MH, Peeters WJ, Windhorst AD, Walsh JC, Kolb HC, Ollers MC, Bussink J, van Dongen GA, van der Kogel A, Lambin P. Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imaging. Proceedings of the National Academy of Sciences of the United States of America. 108: 14620-5. PMID 21873245 DOI: 10.1073/Pnas.1102526108  0.028
2022 Doré V, Doecke JD, Saad ZS, Triana-Baltzer G, Slemmon R, Krishnadas N, Bourgeat P, Huang K, Burnham S, Fowler C, Rainey-Smith SR, Bush AI, Ward L, Robertson J, Martins RN, ... ... Kolb HC, et al. Plasma p217+tau versus NAV4694 amyloid and MK6240 tau PET across the Alzheimer's continuum. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12307. PMID 35415202 DOI: 10.1002/dad2.12307  0.028
2010 van Loon J, Janssen MH, Ollers M, Aerts HJ, Dubois L, Hochstenbag M, Dingemans AM, Lalisang R, Brans B, Windhorst B, van Dongen GA, Kolb H, Zhang J, De Ruysscher D, Lambin P. PET imaging of hypoxia using [18F]HX4: a phase I trial. European Journal of Nuclear Medicine and Molecular Imaging. 37: 1663-8. PMID 20369236 DOI: 10.1007/S00259-010-1437-X  0.027
2014 Walsh JC, Lebedev A, Aten E, Madsen K, Marciano L, Kolb HC. The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities. Antioxidants & Redox Signaling. 21: 1516-54. PMID 24512032 DOI: 10.1089/ars.2013.5378  0.025
2012 Chen L, Zhang Z, Kolb HC, Walsh JC, Zhang J, Guan Y. ¹⁸F-HX4 hypoxia imaging with PET/CT in head and neck cancer: a comparison with ¹⁸F-FMISO. Nuclear Medicine Communications. 33: 1096-102. PMID 22836736 DOI: 10.1097/MNM.0b013e3283571016  0.02
2010 Sanchez-Alavez M, Tabarean IV, Osborn O, Mitsukawa K, Schaefer J, Dubins J, Holmberg KH, Klein I, Klaus J, Gomez LF, Kolb H, Secrest J, Jochems J, Myashiro K, Buckley P, et al. Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons (Diabetes (2010) 59, (43-50)) Diabetes. 59: 756.  0.02
1998 Norman KE, Anderson GP, Kolb HC, Ley K, Ernst B. Sialyl Lewis(x) (sLe(x)) and an sLe(x) mimetic, CGP69669A, disrupt E-selectin-dependent leukocyte rolling in vivo. Blood. 91: 475-83. PMID 9427700  0.02
2010 Sanchez-Alavez M, Tabarean IV, Osborn O, Mitsukawa K, Schaefer J, Dubins J, Holmberg KH, Klein I, Klaus J, Gomez LF, Kolb H, Secrest J, Jochems J, Myashiro K, Buckley P, et al. Insulin causes hyperthermia by direct inhibition of warm-sensitive neurons. Diabetes. 59: 43-50. PMID 19846801 DOI: 10.2337/Db09-1128  0.019
2015 Zegers CM, van Elmpt W, Szardenings K, Kolb H, Waxman A, Subramaniam RM, Moon DH, Brunetti JC, Srinivas SM, Lambin P, Chien D. Repeatability of hypoxia PET imaging using [(18)F]HX4 in lung and head and neck cancer patients: a prospective multicenter trial. European Journal of Nuclear Medicine and Molecular Imaging. 42: 1840-9. PMID 26136164 DOI: 10.1007/S00259-015-3100-Z  0.017
2023 Saloner R, VandeVrede L, Asken BM, Paolillo EW, Gontrum EQ, Wolf A, Lario-Lago A, Milà-Alomà M, Triana-Baltzer G, Kolb HC, Dubal DB, Rabinovici GD, Miller BL, Boxer AL, Casaletto KB, et al. Plasma phosphorylated tau-217 exhibits sex-specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37639492 DOI: 10.1002/alz.13454  0.014
2010 Doss M, Zhang JJ, Bélanger MJ, Stubbs JB, Hostetler ED, Alpaugh K, Kolb HC, Yu JQ. Biodistribution and radiation dosimetry of the hypoxia marker 18F-HX4 in monkeys and humans determined by using whole-body PET/CT. Nuclear Medicine Communications. 31: 1016-24. PMID 20948452 DOI: 10.1097/MNM.0b013e3283407950  0.013
2022 Ashton NJ, Puig-Pijoan A, Milà-Alomà M, Fernández-Lebrero A, García-Escobar G, González-Ortiz F, Kac PR, Brum WS, Benedet AL, Lantero-Rodriguez J, Day TA, Vanbrabant J, Stoops E, Vanmechelen E, Triana-Baltzer G, ... ... Kolb H, et al. Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau immunoassays. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36370462 DOI: 10.1002/alz.12841  0.01
2022 Triana-Baltzer G, Timmers M, De Boer P, Schoene M, Furey M, Bleys C, Vrancken I, Slemmon R, Ceusters M, van Nueten L, Kolb H. Profiling classical neuropsychiatric biomarkers across biological fluids and following continuous lumbar puncture: A guide to sample type and time. Comprehensive Psychoneuroendocrinology. 10: 100116. PMID 35774109 DOI: 10.1016/j.cpnec.2022.100116  0.01
2021 Lukkarinen H, Tesseur I, Pemberton D, Van Der Ark P, Timmers M, Slemmon R, Janssens L, Streffer J, Van Nueten L, Bottelbergs A, Rauramaa T, Koivisto AM, Herukka SK, Korhonen VE, Junkkari A, ... ... Kolb HC, et al. Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus. Journal of Alzheimer's Disease : Jad. PMID 33720890 DOI: 10.3233/JAD-201361  0.01
2016 Ulaner GA, Hyman D, Ross D, Corben A, Chandarlapaty S, Goldfarb S, McArthur H, Erinjeri J, Solomon S, Kolb H, Lyashchenko S, Lewis J, Carrasquillo J. Detection of HER2-positive metastases in patients with HER2-negative primary breast cancer using the 89Zr-DFO-trastuzumab PET/CT. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27151988 DOI: 10.2967/Jnumed.115.172031  0.01
2012 Kolb HC, Padgett HC, Zigler S, Patanella J, Mu F, Gangadharmath UB, Mocharla VP, Scott PJH, Walsh JC. Radiosynthesis of 3'-Deoxy-3'-[18F]Fluorothymidine ([18F]FLT) Radiochemical Syntheses: Radiopharmaceuticals For Positron Emission Tomography. 1: 21-30. DOI: 10.1002/9781118140345.ch3  0.01
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