Yapeng Su - Publications

Affiliations: 
California Institute of Technology, Pasadena, CA 
Area:
systems biology, immunology, oncology, single-cell analysis, chemical engineering,

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen DG, Xie J, Choi J, Ng RH, Zhang R, Li S, Edmark R, Zheng H, Solomon B, Campbell KM, Medina E, Ribas A, Khatri P, Lanier LL, Mease PJ, ... ... Su Y, et al. Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer. Cell Reports. 43: 113872. PMID 38427562 DOI: 10.1016/j.celrep.2024.113872  0.811
2024 Chen DG, Xie J, Su Y, Heath JR. T cell receptor sequences are the dominant factor contributing to the phenotype of CD8 T cells with specificities against immunogenic viral antigens. Cell Reports. 43: 113841. PMID 38341857 DOI: 10.1016/j.celrep.2024.113841  0.75
2023 Heath J, Chen D, Xie J, Choi J, Ng R, Zhang R, Li S, Edmark R, Zheng H, Solomon B, Campbell K, Medina E, Ribas A, Khatri P, Lanier L, ... ... Su Y, et al. An NKG2A biased immune response confers protection for infection, autoimmune disease, and cancer. Research Square. PMID 37886475 DOI: 10.21203/rs.3.rs-3413673/v1  0.81
2023 Chen DG, Xie J, Su Y, Heath JR. T cell receptor sequences are the dominant factor contributing to the phenotype of CD8 T cells with specificities against immunogenic viral antigens. Cell Reports. 113279. PMID 37883974 DOI: 10.1016/j.celrep.2023.113279  0.769
2023 Nag A, Mafi A, Das S, Yu MB, Alvarez-Villalonga B, Kim SK, Su Y, Goddard WA, Heath JR. Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions. Communications Chemistry. 6: 95. PMID 37202473 DOI: 10.1038/s42004-023-00890-w  0.646
2023 Chour W, Choi J, Xie J, Chaffee ME, Schmitt TM, Finton K, DeLucia DC, Xu AM, Su Y, Chen DG, Zhang R, Yuan D, Hong S, Ng AHC, Butler JZ, et al. Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis. Communications Biology. 6: 528. PMID 37193826 DOI: 10.1038/s42003-023-04899-8  0.796
2023 Xu AM, Chour W, DeLucia DC, Su Y, Pavlovitch-Bedzyk AJ, Ng R, Rasheed Y, Davis MM, Lee JK, Heath JR. Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities. Cell Systems. PMID 37001518 DOI: 10.1016/j.cels.2023.03.001  0.753
2022 Duvvuri VR, Baumgartner A, Molani S, Hernandez PV, Yuan D, Roper RT, Matos WF, Robinson M, Su Y, Subramanian N, Goldman JD, Heath JR, Hadlock JJ. Angiotensin-Converting Enzyme (ACE) Inhibitors May Moderate COVID-19 Hyperinflammatory Response: An Observational Study with Deep Immunophenotyping. Health Data Science. 2022. PMID 36817759 DOI: 10.34133/hds.0002  0.555
2022 Goldman JD, Wang K, Röltgen K, Nielsen SCA, Roach JC, Naccache SN, Yang F, Wirz OF, Yost KE, Lee JY, Chun K, Wrin T, Petropoulos CJ, Lee I, Fallen S, ... ... Su Y, et al. Reinfection with SARS-CoV-2 and Waning Humoral Immunity: A Case Report. Vaccines. 11. PMID 36679852 DOI: 10.3390/vaccines11010005  0.641
2022 Heath J, Chour W, Choi J, Xie J, Chaffee M, Schmitt T, Finton K, Delucia D, Xu A, Su Y, Chen D, Zhang R, Yuan D, Hong S, Ng A, et al. Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis. Research Square. PMID 36415462 DOI: 10.21203/rs.3.rs-1090664/v1  0.782
2022 Shemesh A, Su Y, Calabrese DR, Chen D, Arakawa-Hoyt J, Roybal KT, Heath JR, Greenland JR, Lanier LL. Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression. The Journal of Experimental Medicine. 219. PMID 36066491 DOI: 10.1084/jem.20220551  0.639
2022 Ng RH, Lee JW, Baloni P, Diener C, Heath JR, Su Y. Constraint-Based Reconstruction and Analyses of Metabolic Models: Open-Source Python Tools and Applications to Cancer. Frontiers in Oncology. 12: 914594. PMID 35875150 DOI: 10.3389/fonc.2022.914594  0.456
2022 Li J, Zaslavsky M, Su Y, Guo J, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Mallajosyula VVA, et al. KIRCD8 T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Science (New York, N.Y.). eabi9591. PMID 35258337 DOI: 10.1126/science.abi9591  0.67
2022 Su Y, Yuan D, Chen DG, Ng RH, Wang K, Choi J, Li S, Hong S, Zhang R, Xie J, Kornilov SA, Scherler K, Pavlovitch-Bedzyk AJ, Dong S, Lausted C, et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell. PMID 35216672 DOI: 10.1016/j.cell.2022.01.014  0.769
2021 Li J, Zaslavsky M, Su Y, Sikora MJ, van Unen V, Christophersen A, Chiou SH, Chen L, Li J, Ji X, Wilhelmy J, McSween AM, Palanski BA, Aditya Mallajosyula VV, Dhondalay GKR, et al. Human KIR CD8 T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19. Biorxiv : the Preprint Server For Biology. PMID 34981055 DOI: 10.1101/2021.12.23.473930  0.659
2021 Nesterenko PA, McLaughlin J, Tsai BL, Burton Sojo G, Cheng D, Zhao D, Mao Z, Bangayan NJ, Obusan MB, Su Y, Ng RH, Chour W, Xie J, Li YR, Lee D, et al. HLA-A02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses. Cell Reports. 110167. PMID 34919800 DOI: 10.1016/j.celrep.2021.110167  0.806
2021 Krämer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga-García R, Schulte-Schrepping J, Kaiser KM, Rieke GJ, Bischoff J, Monin MB, Hoffmeister C, Schlabe S, De Domenico E, Reusch N, ... ... Su Y, et al. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Immunity. PMID 34592166 DOI: 10.1016/j.immuni.2021.09.002  0.652
2021 Lee JW, Su Y, Baloni P, Chen D, Pavlovitch-Bedzyk AJ, Yuan D, Duvvuri VR, Ng RH, Choi J, Xie J, Zhang R, Murray K, Kornilov S, Smith B, Magis AT, et al. Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19. Nature Biotechnology. PMID 34489601 DOI: 10.1038/s41587-021-01020-4  0.8
2021 Zheng H, Rao AM, Dermadi D, Toh J, Murphy Jones L, Donato M, Liu Y, Su Y, Dai CL, Kornilov SA, Karagiannis M, Marantos T, Hasin-Brumshtein Y, He YD, Giamarellos-Bourboulis EJ, et al. Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity across viruses. Immunity. PMID 33765435 DOI: 10.1016/j.immuni.2021.03.002  0.519
2020 Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai CL, Voillet V, Duvvuri VR, Scherler K, Troisch P, Baloni P, Qin G, Smith B, Kornilov SA, Rostomily C, et al. Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19. Cell. PMID 33171100 DOI: 10.1016/j.cell.2020.10.037  0.789
2020 Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai CL, Voillet V, Duvvuri VR, Scherler K, Troisch P, Baloni P, Qin G, Smith B, Kornilov SA, Rostomily C, et al. Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19. Cell. PMID 33171100 DOI: 10.1016/j.cell.2020.10.037  0.789
2020 Goldman JD, Wang K, Roltgen K, Nielsen SCA, Roach JC, Naccache SN, Yang F, Wirz OF, Yost KE, Lee JY, Chun K, Wrin T, Petropoulos CJ, Lee I, Fallen S, ... ... Su Y, et al. Reinfection with SARS-CoV-2 and Failure of Humoral Immunity: a case report. Medrxiv : the Preprint Server For Health Sciences. PMID 32995830 DOI: 10.1101/2020.09.22.20192443  0.492
2020 Goldman JD, Wang K, Roltgen K, Nielsen SCA, Roach JC, Naccache SN, Yang F, Wirz OF, Yost KE, Lee JY, Chun K, Wrin T, Petropoulos CJ, Lee I, Fallen S, ... ... Su Y, et al. Reinfection with SARS-CoV-2 and Failure of Humoral Immunity: a case report. Medrxiv : the Preprint Server For Health Sciences. PMID 32995830 DOI: 10.1101/2020.09.22.20192443  0.492
2020 Du J, Su Y, Qian C, Yuan D, Miao K, Lee D, Ng AHC, Wijker RS, Ribas A, Levine RD, Heath JR, Wei L. Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells. Nature Communications. 11: 4830. PMID 32973134 DOI: 10.1038/s41467-020-18376-x  0.723
2020 Du J, Su Y, Qian C, Yuan D, Miao K, Lee D, Ng AHC, Wijker RS, Ribas A, Levine RD, Heath JR, Wei L. Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells. Nature Communications. 11: 4830. PMID 32973134 DOI: 10.1038/s41467-020-18376-x  0.723
2020 Lee D, Du J, Yu R, Su Y, Heath JR, Wei L. Visualizing Subcellular Enrichment of Glycogen in Live Cancer Cells by Stimulated Raman Scattering. Analytical Chemistry. PMID 32907318 DOI: 10.1021/Acs.Analchem.0C02348  0.496
2020 Lee D, Du J, Yu R, Su Y, Heath JR, Wei L. Visualizing Subcellular Enrichment of Glycogen in Live Cancer Cells by Stimulated Raman Scattering. Analytical Chemistry. PMID 32907318 DOI: 10.1021/Acs.Analchem.0C02348  0.496
2020 Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, et al. Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories. Biorxiv : the Preprint Server For Biology. PMID 32766585 DOI: 10.1101/2020.07.27.224063  0.825
2020 Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, et al. Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories. Biorxiv : the Preprint Server For Biology. PMID 32766585 DOI: 10.1101/2020.07.27.224063  0.825
2020 Su Y, Ko ME, Cheng H, Zhu R, Xue M, Wang J, Lee JW, Frankiw L, Xu A, Wong S, Robert L, Takata K, Yuan D, Lu Y, Huang S, et al. Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line. Nature Communications. 11: 2345. PMID 32393797 DOI: 10.1038/S41467-020-15956-9  0.797
2020 Su Y, Li G, Ko M, Cheng H, Zhu R, Xue M, Robert L, Levine R, Ribas A, Nolan G, Wei W, Plevritis S, Baltimore D, Heath JR. Abstract 6585: Systems biology for investigating drug resistance mechanism of melanoma Cancer Research. 80: 6585-6585. DOI: 10.1158/1538-7445.Am2020-6585  0.711
2019 Peng S, Zaretsky JM, Ng AHC, Chour W, Bethune MT, Choi J, Hsu A, Holman E, Ding X, Guo K, Kim J, Xu AM, Heath JE, Noh WJ, Zhou J, ... Su Y, et al. Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood. Cell Reports. 28: 2728-2738.e7. PMID 31484081 DOI: 10.1016/J.Celrep.2019.07.106  0.805
2019 Su Y, Bintz M, Yang Y, Robert L, Ng AHC, Liu V, Ribas A, Heath JR, Wei W. Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance. Plos Computational Biology. 15: e1007034. PMID 31166947 DOI: 10.1371/Journal.Pcbi.1007034  0.544
2019 Su Y, Bintz M, Yang Y, Robert L, Ng AHC, Liu V, Ribas A, Heath JR, Wei W. Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance. Plos Computational Biology. 15: e1007034. PMID 31166947 DOI: 10.1371/Journal.Pcbi.1007034  0.544
2019 Li G, Bethune MT, Wong S, Joglekar AV, Leonard MT, Wang JK, Kim JT, Cheng D, Peng S, Zaretsky JM, Su Y, Luo Y, Heath JR, Ribas A, Witte ON, et al. T cell antigen discovery via trogocytosis. Nature Methods. 16: 183-190. PMID 30700903 DOI: 10.1038/S41592-018-0305-7  0.804
2018 Xu AM, Liu Q, Takata KL, Jeoung S, Su Y, Antoshechkin I, Chen S, Thomson M, Heath JR. Integrated measurement of intracellular proteins and transcripts in single cells. Lab On a Chip. PMID 30178802 DOI: 10.1039/C8Lc00639C  0.749
2018 Xu AM, Liu Q, Takata KL, Jeoung S, Su Y, Antoshechkin I, Chen S, Thomson M, Heath JR. Integrated measurement of intracellular proteins and transcripts in single cells. Lab On a Chip. PMID 30178802 DOI: 10.1039/C8Lc00639C  0.749
2018 Li G, So AY, Sookram R, Wong S, Wang JK, Ouyang Y, He P, Su Y, Casellas R, Baltimore D. Epigenetic silencing of miR-125b is required for normal B cell development. Blood. PMID 29555645 DOI: 10.1182/Blood-2018-01-824540  0.375
2018 Zhou J, Bethune MT, Malkova N, Sutherland AM, Comin-Anduix B, Su Y, Baltimore D, Ribas A, Heath JR. A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell transfer tumor eradication. Plos One. 13: e0191634. PMID 29360859 DOI: 10.1371/Journal.Pone.0191634  0.667
2017 Su Y, Wei W, Robert L, Xue M, Tsoi J, Garcia-Diaz A, Homet Moreno B, Kim J, Ng RH, Lee JW, Koya RC, Comin-Anduix B, Graeber TG, Ribas A, Heath JR. Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 29229836 DOI: 10.1073/Pnas.1712064115  0.637
2017 Su Y, Wei W, Robert L, Xue M, Tsoi J, Garcia-Diaz A, Homet Moreno B, Kim J, Ng RH, Lee JW, Koya RC, Comin-Anduix B, Graeber TG, Ribas A, Heath JR. Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 29229836 DOI: 10.1073/Pnas.1712064115  0.637
2017 Su Y, Shi Q, Wei W. Single cell proteomics in biomedicine: High-dimensional data acquisition, visualization and analysis. Proteomics. PMID 28128880 DOI: 10.1002/pmic.201600267  0.531
2017 Su Y, Shi Q, Wei W. Single cell proteomics in biomedicine: High-dimensional data acquisition, visualization and analysis. Proteomics. PMID 28128880 DOI: 10.1002/pmic.201600267  0.531
2017 Su Y, Wei W, Robert L, Tsoi J, Xue M, Kim J, Graeber T, Levine R, Ribas A, Heath J. Abstract 2069: Overcoming drug resistance by targeting melanoma dedifferentiation through information-theoretic analysis and single cell proteomics Cancer Research. 77: 2069-2069. DOI: 10.1158/1538-7445.Am2017-2069  0.59
2016 Wei W, Shin YS, Xue M, Matsutani T, Masui K, Yang H, Ikegami S, Gu Y, Herrmann K, Johnson D, Ding X, Hwang K, Kim J, Zhou J, Su Y, et al. Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma. Cancer Cell. 29: 563-73. PMID 27070703 DOI: 10.1016/J.Ccell.2016.03.012  0.78
2016 Wei W, Shin YS, Xue M, Matsutani T, Masui K, Yang H, Ikegami S, Gu Y, Herrmann K, Johnson D, Ding X, Hwang K, Kim J, Zhou J, Su Y, et al. Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma. Cancer Cell. 29: 563-73. PMID 27070703 DOI: 10.1016/J.Ccell.2016.03.012  0.78
2016 Xue M, Wei W, Su Y, Johnson D, Heath JR. Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells. Journal of the American Chemical Society. PMID 26916347 DOI: 10.1021/Jacs.5B12187  0.624
2016 Xue M, Wei W, Su Y, Johnson D, Heath JR. Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells. Journal of the American Chemical Society. PMID 26916347 DOI: 10.1021/Jacs.5B12187  0.624
2016 Su Y, Wei W, Xue M, Robert L, Tsoi J, Graeber T, Ribas A, Heath J. Abstract 879: Single cell analysis resolves combinatory targeted therapy for arresting the BRAFi-induced cellular dedifferentiation of metastatic melanomas Cancer Research. 76: 879-879. DOI: 10.1158/1538-7445.Am2016-879  0.524
2015 Xue M, Wei W, Su Y, Kim J, Shin YS, Mai WX, Nathanson DA, Heath JR. Chemical methods for the simultaneous quantitation of metabolites and proteins from single cells. Journal of the American Chemical Society. 137: 4066-9. PMID 25789560 DOI: 10.1021/Jacs.5B00944  0.798
2015 Xue M, Wei W, Su Y, Kim J, Shin YS, Mai WX, Nathanson DA, Heath JR. Chemical methods for the simultaneous quantitation of metabolites and proteins from single cells. Journal of the American Chemical Society. 137: 4066-9. PMID 25789560 DOI: 10.1021/Jacs.5B00944  0.798
2015 Xue M, Wei W, Su Y, Shin YS, Kim J, Heath JR. Abstract 1995: Developing integrated single-cell metabolic/proteomic assays Cancer Research. 75: 1995-1995. DOI: 10.1158/1538-7445.Am2015-1995  0.561
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