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Gerd Folkers - Publications

Affiliations: 
pharmaceutical chemistry ETH Zürich, Zürich, ZH, Switzerland 
Website:
http://www.collegium.ethz.ch/en/ueber-uns/mitarbeiter/prof-dr-gerd-folkers/

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Pliska V, Folkers G, Spiwok V. Thermodynamics of the interaction between oxytocin and its myometrial receptor in sheep: A stepwise binding mechanism Biochemical Pharmacology. 91: 119-127. PMID 25010721 DOI: 10.1016/j.bcp.2014.06.025  0.4
2014 Hiss JA, Reutlinger M, Koch CP, Perna AM, Schneider P, Rodrigues T, Haller S, Folkers G, Weber L, Baleeiro RB, Walden P, Wrede P, Schneider G. Combinatorial chemistry by ant colony optimization. Future Medicinal Chemistry. 6: 267-80. PMID 24575965 DOI: 10.4155/fmc.13.203  0.4
2014 Atmanspacher H, Bezzola Lambert L, Folkers G, Schubiger PA. Relevance relations for the concept of reproducibility Journal of the Royal Society Interface. 11. DOI: 10.1098/rsif.2013.1030  0.4
2014 Mannhold R, Kubinyi H, Folkers G. Preface In Vivo Models For Drug Discovery. xxix-xxx. DOI: 10.1002/3527609164  0.4
2013 Folkers G. Freiheit in der forschung Pharmazie. 68: 506-520. PMID 23923630 DOI: 10.1691/ph.2013.6510  0.4
2013 Koch CP, Perna AM, Weissmüller S, Bauer S, Pillong M, Baleeiro RB, Reutlinger M, Folkers G, Walden P, Wrede P, Hiss JA, Waibler Z, Schneider G. Exhaustive proteome mining for functional MHC-I ligands. Acs Chemical Biology. 8: 1876-81. PMID 23772559 DOI: 10.1021/cb400252t  0.4
2013 Koch CP, Perna AM, Pillong M, Todoroff NK, Wrede P, Folkers G, Hiss JA, Schneider G. Scrutinizing MHC-I binding peptides and their limits of variation. Plos Computational Biology. 9: e1003088. PMID 23754940 DOI: 10.1371/journal.pcbi.1003088  0.4
2013 Krummenacher P, Kut E, Folkers G, Brugger P. Naloxone modulates visual judgments of similarity but not dissimilarity. Cognitive, Affective & Behavioral Neuroscience. 13: 567-74. PMID 23494456 DOI: 10.3758/s13415-013-0155-9  0.4
2012 Schaffner N, Folkers G, Käppeli S, Musholt M, Hofbauer GFL, Candia V. A New Tool for Real-Time Pain Assessment in Experimental and Clinical Environments Plos One. 7. PMID 23226449 DOI: 10.1371/journal.pone.0051014  0.4
2012 Kusserow M, Candia V, Amft O, Hildebrandt H, Folkers G, Tröster G. Monitoring stage fright outside the laboratory: an example in a professional musician using wearable sensors. Medical Problems of Performing Artists. 27: 21-30. PMID 22543319  0.4
2012 Pliska V, Folkers G. Chemistry and chemists in the story of insulin | Inzulín:chemie a chemici v jeho historii Diabetologie Metabolismus Endokrinologie Vyziva. 15: 111-118.  0.4
2011 Kut E, Candia V, Von Overbeck J, Pok J, Fink D, Folkers G. Pleasure-related analgesia activates opioid-insensitive circuits Journal of Neuroscience. 31: 4148-4153. PMID 21411655 DOI: 10.1523/JNEUROSCI.3736-10.2011  0.4
2011 Stern J, Candia V, Porchet RI, Krummenacher P, Folkers G, Schedlowski M, Ettlin DA, Schönbächler G. Placebo-mediated, Naloxone-sensitive suggestibility of short-term memory performance. Neurobiology of Learning and Memory. 95: 326-34. PMID 21277984 DOI: 10.1016/j.nlm.2011.01.005  0.4
2010 Krummenacher P, Candia V, Folkers G, Schedlowski M, Schönbächler G. Prefrontal cortex modulates placebo analgesia Pain. 148: 368-374. PMID 19875233 DOI: 10.1016/j.pain.2009.09.033  0.4
2010 Kusserow M, Tröster G, Candia V, Folkers G, Amft O, Hildebrandt H. Wearable monitoring of stage fright in professional musicians Proceedings - International Symposium On Wearable Computers, Iswc. DOI: 10.1109/ISWC.2010.5665852  0.4
2008 Schaffner N, Wittwer A, Kut E, Folkers G, Benninger DH, Candia V. Heat pain threshold and tolerance show no left-right perceptual differences at complementary sites of the human forearm Neuroscience Letters. 440: 309-313. PMID 18571850 DOI: 10.1016/j.neulet.2008.05.084  0.4
2008 Folkers G, Merz A. Hydrophobic Fields in Quantitative Structure-Activity Relationships Lipophilicity in Drug Action and Toxicology. 4: 219-232. DOI: 10.1002/9783527614998.ch13  0.4
2007 Kut E, Schaffner N, Wittwer A, Candia V, Brockmann M, Storck C, Folkers G. Changes in self-perceived role identity modulate pain perception Pain. 131: 191-201. PMID 17521808 DOI: 10.1016/j.pain.2007.04.012  0.4
2007 Iqbal J, Scapozza L, Folkers G, Müller CE. Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 846: 281-290. PMID 17023224 DOI: 10.1016/j.jchromb.2006.09.018  0.4
2007 Huber RD, Gao B, Pfändler MAS, Zhang-Fu W, Leuthold S, Hagenbuch B, Folkers G, Meier PJ, Stieger B. Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain American Journal of Physiology - Cell Physiology. 292: C795-C806. PMID 16971491 DOI: 10.1152/ajpcell.00597.2005  0.4
2007 Folkers G, Wittwer A. Drug design and emotion Aip Conference Proceedings. 958: 3-8. DOI: 10.1063/1.2825830  0.4
2007 Testa B, Krämer SD, Wunderli-Allenspach H, Folkers G. Pharmacokinetic Profiling in Drug Research Pharmacokinetic Profiling in Drug Research. 1-493. DOI: 10.1002/9783906390468  0.4
2007 van de Waterbeemd H, Testa B, Folkers G. Computer-Assisted Lead Finding and Optimization: Current Tools for Medicinal Chemistry Computer-Assisted Lead Finding and Optimization: Current Tools For Medicinal Chemistry. 1-553. DOI: 10.1002/9783906390406  0.4
2006 Kapková P, Heller E, Kugelmann E, Faber J, Bringmann G, Kessler U, Folkers G, Holzgrabe U. Random chemistry as a new tool for the generation of small-compound libraries. Archiv Der Pharmazie. 339: 489-97. PMID 16929558 DOI: 10.1002/ardp.200600084  0.4
2006 Otto VI, Damoc E, Cueni LN, Schürpf T, Frei R, Ali S, Callewaert N, Moise A, Leary JA, Folkers G, Przybylski M. N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry. Glycobiology. 16: 1033-44. PMID 16877748 DOI: 10.1093/glycob/cwl032  0.4
2006 Birringer MS, Perozzo R, Kut E, Stillhart C, Surber W, Scapozza L, Folkers G. High-level expression and purification of human thymidine kinase 1: Quaternary structure, stability, and kinetics Protein Expression and Purification. 47: 506-515. PMID 16473525 DOI: 10.1016/j.pep.2006.01.001  0.4
2006 Limacher A, Kloer DP, Flückiger S, Folkers G, Crameri R, Scapozza L. The crystal structure of Aspergillus fumigatus cyclophilin reveals 3D domain swapping of a central element Structure. 14: 185-195. PMID 16472738 DOI: 10.1016/j.str.2005.10.015  0.4
2006 Lack G, Homberger-Zizzari E, Folkers G, Scapozza L, Perozzo R. Recombinant expression and biochemical characterization of the unique elongating β-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates Journal of Biological Chemistry. 281: 9538-9546. PMID 16467310 DOI: 10.1074/jbc.M509119200  0.4
2006 Folkers G, Ishai A, Rudin M, Schubiger PA, Bräutigam M, Möhler H, Märki HP. Imaging in biomedical research: Mini-Symposium of the Division for Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS), at the Department of Chemistry, University of Basel, May 18, 2006 Chimia. 60: 805-814. DOI: 10.2533/chimia.2006.805  0.4
2006 Eberle AN, Wennemers H, Nayler O, Ernst B, Folkers G, Pliska V, Bürgisser E. Journal of Receptors and Signal Transduction: Preface Journal of Receptors and Signal Transduction. 26: 359-360. DOI: 10.1080/10799890600943318  0.4
2005 Kapková P, Heller E, Unger M, Folkers G, Holzgrabe U. Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor. Journal of Medicinal Chemistry. 48: 7496-9. PMID 16279811 DOI: 10.1021/jm058041z  0.4
2005 Kostrewa D, Winkler FK, Folkers G, Scapozza L, Perozzo R. The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum. Protein Science : a Publication of the Protein Society. 14: 1570-80. PMID 15930004 DOI: 10.1110/ps.051373005  0.4
2005 de Graaf C, Pospisil P, Pos W, Folkers G, Vermeulen NP. Binding mode prediction of cytochrome p450 and thymidine kinase protein-ligand complexes by consideration of water and rescoring in automated docking. Journal of Medicinal Chemistry. 48: 2308-18. PMID 15801824 DOI: 10.1021/jm049650u  0.4
2005 Hofstetter B, Vuong V, Broggini-Tenzer A, Bodis S, Ciernik IF, Fabbro D, Wartmann M, Folkers G, Pruschy M. Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo Clinical Cancer Research. 11: 1588-1596. PMID 15746064 DOI: 10.1158/1078-0432.CCR-04-1800  0.4
2005 Birringer MS, Claus MT, Folkers G, Kloer DP, Schulz GE, Scapozza L. Structure of a type II thymidine kinase with bound dTTP Febs Letters. 579: 1376-1382. PMID 15733844 DOI: 10.1016/j.febslet.2005.01.034  0.4
2005 Meier Y, Cavallaro M, Roos M, Pauli-Magnus C, Folkers G, Meier PJ, Fattinger K. Incidence of drug-i'nduced liver injury in medical inpatients European Journal of Clinical Pharmacology. 61: 135-143. PMID 15726344 DOI: 10.1007/s00228-004-0888-z  0.4
2005 Yarim M, Moro S, Huber R, Meier PJ, Kaseda C, Kashima T, Hagenbuch B, Folkers G. Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates Bioorganic and Medicinal Chemistry. 13: 463-471. PMID 15598568 DOI: 10.1016/j.bmc.2004.10.009  0.4
2004 Raić-Malić S, Johayem A, Ametamey SM, Batinac S, De Clercq E, Folkers G, Scapozza L. Synthesis, 18F-radiolabelling and biological evaluations of C-6 alkylated pyrimidine nucleoside analogues Nucleosides, Nucleotides and Nucleic Acids. 23: 1707-1721. PMID 15598073 DOI: 10.1081/NCN-200033914  0.4
2004 Perozzo R, Folkers G, Scapozza L. Thermodynamics of protein-ligand interactions: History, presence, and future aspects Journal of Receptors and Signal Transduction. 24: 1-52. PMID 15344878 DOI: 10.1081/RRS-120037896  0.4
2004 Otto VI, Schürpf T, Folkers G, Cummings RD. Sialylated complex-type N-glycans enhance the signaling activity of soluble intercellular adhesion molecule-1 in mouse astrocytes. The Journal of Biological Chemistry. 279: 35201-9. PMID 15201278 DOI: 10.1074/jbc.M404947200  0.4
2004 Cavalli A, Prota AE, Stehle T, Dermody TS, Recanatini M, Folkers G, Scapozza L. A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structure. Biophysical Journal. 86: 3423-31. PMID 15189844 DOI: 10.1529/biophysj.103.030825  0.4
2004 Gonser S, Crompton NE, Folkers G, Weber E. Increased radiation toxicity by enhanced apoptotic clearance of HL-60 cells in the presence of the pentapeptide thymopentin, which selectively binds to apoptotic cells. Mutation Research. 558: 19-26. PMID 15036115 DOI: 10.1016/j.mrgentox.2003.10.010  0.4
2004 Altznauer F, Conus S, Cavalli A, Folkers G, Simon HU. Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis. The Journal of Biological Chemistry. 279: 5947-57. PMID 14612448 DOI: 10.1074/jbc.M308576200  0.4
2004 Folkers G. Pharmaceutical Chemistry at the ETH Zürich Chimia. 58: 707-710.  0.4
2004 Pospisil P, Folkers G. Making the best account of molecular docking in drug design Fabad Journal of Pharmaceutical Sciences. 29: 81-92.  0.4
2003 Pospisil P, Ballmer P, Scapozza L, Folkers G. Tautomerism in computer-aided drug design. Journal of Receptor and Signal Transduction Research. 23: 361-71. PMID 14753297 DOI: 10.1081/RRS-120026975  0.4
2003 Prekupec S, Svedruzić D, Gazivoda T, Mrvos-Sermek D, Nagl A, Grdisa M, Pavelić K, Balzarini J, De Clercq E, Folkers G, Scapozza L, Mintas M, Raić-Malić S. Synthesis and biological evaluation of iodinated and fluorinated 9-(2-hydroxypropyl) and 9-(2-hydroxyethoxy)methyl purine nucleoside analogues. Journal of Medicinal Chemistry. 46: 5763-72. PMID 14667229 DOI: 10.1021/jm0308747  0.4
2003 Russ P, Schelling P, Scapozza L, Folkers G, Clercq ED, Marquez VE. Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine. Journal of Medicinal Chemistry. 46: 5045-54. PMID 14584954 DOI: 10.1021/jm030241s  0.4
2003 Klein CD, Schiffmann R, Folkers G, Piana S, Röthlisberger U. Protonation states of methionine aminopeptidase and their relevance for inhibitor binding and catalytic activity. The Journal of Biological Chemistry. 278: 47862-7. PMID 14514693 DOI: 10.1074/jbc.M305325200  0.4
2003 Pizzagalli F, Varga Z, Huber RD, Folkers G, Meier PJ, St-Pierre MV. Identification of steroid sulfate transport processes in the human mammary gland. The Journal of Clinical Endocrinology and Metabolism. 88: 3902-12. PMID 12915686 DOI: 10.1210/jc.2003-030174  0.4
2003 Spadola L, Novellino E, Folkers G, Scapozza L. Homology modelling and docking studies on Varicella Zoster Virus Thymidine kinase. European Journal of Medicinal Chemistry. 38: 413-9. PMID 12750029 DOI: 10.1016/S0223-5234(03)00053-9  0.4
2003 Džolić Z, Cetina M, Kovaček D, Hergold-Brundić A, Mrvoš-Sermek D, Nagl A, Slade N, Pavelić K, Balzarini J, De Clercq E, Zerbe O, Folkers G, Scapozza L, Mintas M. Molecular structures and ab initio molecular orbital calculations of the optically active derivatives of 1-aminocyclopropane-1-carboxylic acid Journal of Molecular Structure. 655: 229-241. DOI: 10.1016/S0022-2860(03)00255-2  0.4
2003 Dahinden A, Rau K, Schmidt R, Folkers G. Pathways to a new pharmaceutical total quality. Part 4: Quality costs and enterprise resource planning systems | Wege zu einer neuen pharmazeutischen 'total quality'. Teil 4: Qualitätskosten und enterprise resource planning system Pharmazeutische Industrie. 65: 13-20.  0.4
2003 Folkers G, Pliska V, Birringer M. Structure and effect of drugs - Where is the relationship? | Struktur und wirkung - Wo ist die beziehung? Deutsche Apotheker Zeitung. 143: 52-56.  0.4
2003 Khov-Tran VV, Hanser CFW, Folkers G. Vireal Lab - From instruction to construction Chimia. 57: 121-127.  0.4
2003 Folkers G, Kubinyi H, Hoffmann R, Langer T, Scapozza L, Johner R, Ballmer P, Jahnke W. Focal point: Medicinal chemistry: A. Ligand-receptor interactions: From understanding to design Chimia. 57: 57-59.  0.4
2003 Lichtsteiner S, Rizzotti S, Weber C, Vögtli A, Burkhart H, Neier R, Van Khov-Tran V, Folkers G, Ernst B. Pharmasquare (Pharma2) Chimia. 57: 116-120.  0.4
2003 Folkers G, Kessler U. Random chemistry: Look for the unexpected Current Drug Discovery. 33-36.  0.4
2002 Klein CDP, Folkers G. Understanding the Selectivity of Fumagillin for the Methionine Aminopeptidase Type II Oncology Research. 13: 513-520. PMID 12899241  0.4
2002 Pospisil P, Kuoni T, Scapozza L, Folkers G. Methodology and problems of protein-ligand docking: case study of dihydroorotate dehydrogenase, thymidine kinase, and phosphodiesterase 4. Journal of Receptor and Signal Transduction Research. 22: 141-54. PMID 12503612 DOI: 10.1081/RRS-120014592  0.4
2002 Kratz F, Warnecke A, Scheuermann K, Stockmar C, Schwab J, Lazar P, Drückes P, Esser N, Drevs J, Rognan D, Bissantz C, Hinderling C, Folkers G, Fichtner I, Unger C. Probing the cysteine-34 position of endogenous serum albumin with thiol-binding doxorubicin derivatives. Improved efficacy of an acid-sensitive doxorubicin derivative with specific albumin-binding properties compared to that of the parent compound. Journal of Medicinal Chemistry. 45: 5523-33. PMID 12459020 DOI: 10.1021/jm020276c  0.4
2002 Lerch M, Gafner V, Bader R, Christen B, Folkers G, Zerbe O. Bovine pancreatic polypeptide (bPP) undergoes significant changes in conformation and dynamics upon binding to DPC micelles. Journal of Molecular Biology. 322: 1117-33. PMID 12367532 DOI: 10.1016/S0022-2836(02)00889-6  0.4
2002 Pizzagalli F, Hagenbuch B, Stieger B, Klenk U, Folkers G, Meier PJ. Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter Molecular Endocrinology. 16: 2283-2296. PMID 12351693 DOI: 10.1210/me.2001-0309  0.4
2002 Flückiger S, Scapozza L, Mayer C, Blaser K, Folkers G, Crameri R. Immunological and structural analysis of IgE-mediated cross-reactivity between manganese superoxide dismutases. International Archives of Allergy and Immunology. 128: 292-303. PMID 12218367  0.4
2002 Otto VI, Gloor SM, Frentzel S, Gilli U, Ammann E, Hein AE, Folkers G, Trentz O, Kossmann T, Morganti-Kossmann MC. The production of macrophage inflammatory protein-2 induced by soluble intercellular adhesion molecule-1 in mouse astrocytes is mediated by src tyrosine kinases and p42/44 mitogen-activated protein kinase. Journal of Neurochemistry. 80: 824-34. PMID 11948246 DOI: 10.1046/j.0022-3042.2001.00748.x  0.4
2002 Flückiger S, Mittl PR, Scapozza L, Fijten H, Folkers G, Grütter MG, Blaser K, Crameri R. Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution. Journal of Immunology (Baltimore, Md. : 1950). 168: 1267-72. PMID 11801664  0.4
2002 Pospisil P, Pilger BD, Marveggio S, Schelling P, Wurth C, Scapozza L, Folkers G, Pongracic M, Mintas M, Malic SR. Synthesis, kinetics, and molecular docking of novel 9-(2-hydroxypropyl)purine nucleoside analogs as ligands of herpesviral thymidine kinases Helvetica Chimica Acta. 85: 3237-3250. DOI: 10.1002/1522-2675(200210)85:10<3237::AID-HLCA3237>3.0.CO;2-3  0.4
2002 Sulpizi M, Folkers G, Rothlisberger U, Carloni P, Scapozza L. Applications of density functional theory-based methods in medicinal chemistry Quantitative Structure-Activity Relationships. 21: 173-181. DOI: 10.1002/1521-3838(200207)21:2<173::AID-QSAR173>3.0.CO;2-B  0.4
2002 Dahinden A, Schmidt R, Folkers G. Pathways to a new pharmaceutical total quality | Wege zu einer neuen pharmazeutischen, total quality Pharmazeutische Industrie. 64: 1233-1238.  0.4
2002 Eberle AN, Folkers G, Pliska V, Bürgisser E. 9th Swiss workshop of methodology in receptor research Zürich, September 23-26, 2001; Preface Journal of Receptors and Signal Transduction. 22: xi-xii.  0.4
2002 Dahinden A, Schmidt R, Folkers G. Pathways to a new pharmaceutical total quality. Part 2: Integration of balanced scorecard and quality costs - A management tool for pharmaceutical continuous improvement | Wege zu einer neuen pharmazeutischen 'Total quality'. Teil 2: Integration balanced scorecard und qualitätskosten- Ein management-tool für das pharmazeutische "kaizen" Pharmazeutische Industrie. 64: 1126-1133.  0.4
2002 Dahinden A, Schmidt R, Folkers G. Towards a new pharmaceutical total quality. Part 1: Good manufacturing practice (GMP) is not the same as total quality | Wege zu einer neuen pharmazeutischen, 'total quality': Teil 1: Good manufacturing practice (GMP) ist nicht gleich, 'total quality' Pharmazeutische Industrie. 64: 1027-1033.  0.4
2001 Cavalli A, Dezi C, Folkers G, Scapozza L, Recanatini M. Three-dimensional model of the cyclin-dependent kinase 1 (CDK1): Ab initio active site parameters for molecular dynamics studies of CDKs Proteins: Structure, Function and Genetics. 45: 478-485. PMID 11746695 DOI: 10.1002/prot.10013  0.4
2001 Demuth C, Zerbe O, Rognan D, Söll R, Beck-Sickinger A, Folkers G, Spichiger UE. A rationally designed oligopeptide shows significant conformational changes upon binding to sulphate ions Biosensors and Bioelectronics. 16: 783-789. PMID 11679256 DOI: 10.1016/S0956-5663(01)00221-4  0.4
2001 Zhou X, Gonnet G, Hallett M, Münchbach M, Folkers G, James P. Cell fingerprinting: An approach to classifying cells according to mass profiles of digests of protein extracts Proteomics. 1: 683-690. PMID 11678037  0.4
2001 Wurth C, Thomas RM, Folkers G, Scapozza L. Folding and self-assembly of herpes simplex virus type 1 thymidine kinase. Journal of Molecular Biology. 313: 657-70. PMID 11676546 DOI: 10.1006/jmbi.2001.5060  0.4
2001 Schelling P, Folkers G, Scapozza L. A spectrophotometric assay for quantitative determination of kcat of herpes simplex virus type 1 thymidine kinase substrates Analytical Biochemistry. 295: 82-87. PMID 11476548 DOI: 10.1006/abio.2001.5191  0.4
2001 Maecker HT, Dunn HS, Suni MA, Khatamzas E, Pitcher CJ, Bunde T, Persaud N, Trigona W, Fu TM, Sinclair E, Bredt BM, McCune JM, Maino VC, Kern F, Picker LJ. Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. Journal of Immunological Methods. 255: 27-40. PMID 11470284 DOI: 10.1016/S0022-1759(01)00416-1  0.4
2001 Reinelt S, Marti M, Dédier S, Reitinger T, Folkers G, López De Castro JA, Rognan D. β-Amino Acid Scan of a Class I Major Histocompatibility Complex-restricted Alloreactive T-cell Epitope Journal of Biological Chemistry. 276: 24525-24530. PMID 11342555 DOI: 10.1074/jbc.M102772200  0.4
2001 Reinelt S, Dédier S, Asuni G, Folkers G, Rognan D. Mutation of Cys-67 Alters the Thermodynamic Stability of the Human Leukocyte Antigen HLA-B*2705 Journal of Biological Chemistry. 276: 18472-18477. PMID 11279190 DOI: 10.1074/jbc.M101282200  0.4
2001 Rognan D, Mukhija S, Folkers G, Zerbe O. NMR-restrained docking of a peptidic inhibitor to the N-terminal domain of the phosphoenolpyruvate: Sugar phosphotransferase enzyme I Journal of Computer-Aided Molecular Design. 15: 103-115. PMID 11272698 DOI: 10.1023/A:1008145813315  0.4
2001 Wurth C, Kessler U, Vogt J, Schulz GE, Folkers G, Scapozza L. The effect of substrate binding on the conformation and structural stability of Herpes simplex virus type 1 thymidine kinase Protein Science. 10: 63-73. PMID 11266595 DOI: 10.1110/ps.27401  0.4
2001 Sulpizi M, Schelling P, Folkers G, Carloni P, Scapozza L. The rational of catalytic activity of herpes simplex virus thymidine kinase. A combined biochemical and quantum chemical study Journal of Biological Chemistry. 276: 21692-21697. PMID 11262392 DOI: 10.1074/jbc.M010223200  0.4
2000 Bissantz C, Folkers G, Rognan D. Protein-based virtual screening of chemical databases. 1. Evaluation of different docking/scoring combinations Journal of Medicinal Chemistry. 43: 4759-4767. PMID 11123984 DOI: 10.1021/jm001044l  0.4
2000 Vogt J, Perozzo R, Pautsch A, Prota A, Schelling P, Pilger B, Folkers G, Scapozza L, Schulz GE. Nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography Proteins: Structure, Function and Genetics. 41: 545-553. PMID 11056041 DOI: 10.1002/1097-0134(20001201)41:4<545::AID-PROT110>3.0.CO;2-8  0.4
2000 Zhou X, Alber F, Folkers G, Gonnet GH, Chelvanayagam G. An analysis of the helix-to-strand transition between peptides with identical sequence Proteins: Structure, Function and Genetics. 41: 248-256. PMID 10966577 DOI: 10.1002/1097-0134(20001101)41:2<248::AID-PROT90>3.0.CO;2-J  0.4
2000 Prota A, Vogt J, Pilger B, Perozzo R, Wurth C, Marquez VE, Russ P, Schulz GE, Folkers G, Scapozza L. Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine Biochemistry. 39: 9597-9603. PMID 10924157 DOI: 10.1021/bi000668q  0.4
2000 Dédier S, Reinelt S, Reitinger T, Folkers G, Rognan D. Thermodynamic stability of HLA-B*2705-peptide complexes: Effect of peptide and major histocompatibility complex protein mutations Journal of Biological Chemistry. 275: 27055-27061. PMID 10823832 DOI: 10.1074/jbc.M002777200  0.4
2000 Perozzo R, Jelesarov I, Bosshard HR, Folkers G, Scapozza L. Compulsory order of substrate binding to herpes simplex virus type 1 thymidine kinase: A calorimetric study Journal of Biological Chemistry. 275: 16139-16145. PMID 10747922 DOI: 10.1074/jbc.M000509200  0.4
2000 Amrhein I, Wurth C, Bohner T, Hofbauer R, Folkers G, Scapozza L. Highly purified recombinant varicella zoster virus thymidine kinase is a homodimer Protein Expression and Purification. 18: 338-345. PMID 10733888 DOI: 10.1006/prep.2000.1201  0.4
2000 Folkers G. Pharmaceutica Acta Helvetiae: Editorial Pharmaceutica Acta Helvetiae. 74: v. DOI: 10.1016/S0031-6865(00)00026-1  0.4
2000 Scapozza L, Ballmer P, Johner R, Perozzo R, Pilger B, Pospisil P, Prota A, Schelling P, Spadola L, Wurth C, Folkers G. Extended substrate acceptance of Herpes simplex virus type 1 thymidine kinase: A new chance for gene and antiviral therapy Chimia. 54: 663-668.  0.4
2000 Reto B, Lerch M, Folkers G, Zerbe O. Using structural information of peptides, derived from NMR spectroscopy, in pharmaceutical chemistry Chimia. 54: 627-632.  0.4
1999 Pilger BD, Perozzo R, Alber F, Wurth C, Folkers G, Scapozza L. Substrate diversity of herpes simplex virus thymidine kinase. Impact of the kinematics of the enzyme Journal of Biological Chemistry. 274: 31967-31973. PMID 10542226 DOI: 10.1074/jbc.274.45.31967  0.4
1999 Gonser S, Weber E, Folkers G. Peptides and polypeptides as modulators of the immune response: Thymopentin - An example with unknown mode of action Pharmaceutica Acta Helvetiae. 73: 265-273. PMID 10443171 DOI: 10.1016/S0031-6865(99)00005-9  0.4
1999 Weber PJ, Eckhard CP, Gonser S, Otto H, Folkers G, Beck-Sickinger AG. On the role of thymopoietins in cell proliferation. Immunochemical evidence for new members of the human thymopoietin family. Biological Chemistry. 380: 653-60. PMID 10430029 DOI: 10.1515/BC.1999.081  0.4
1999 Poenaru S, Lamas JR, Folkers G, López de Castro JA, Seebach D, Rognan D. Nonapeptide analogues containing (R)-3-hydroxybutanoate and beta-homoalanine oligomers: synthesis and binding affinity to a class I major histocompatibility complex protein. Journal of Medicinal Chemistry. 42: 2318-31. PMID 10395472 DOI: 10.1021/jm981123l  0.4
1999 Kussmann-Gerber S, Wurth C, Scapozza L, Pilger BD, Pliška V, Folkers G. Interaction of the recombinant Herpes Simplex Virus type 1 thymidine kinase with thymidine and aciclovir: A kinetic study Nucleosides and Nucleotides. 18: 311-330. PMID 10358938  0.4
1999 Christians FC, Scapozza L, Crameri A, Folkers G, Stemmer WPC. Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling Nature Biotechnology. 17: 259-264. PMID 10096293 DOI: 10.1038/7003  0.4
1999 Dédier S, Krebs S, Lamas JR, Poenaru S, Folkers G, López de Castro JA, Seebach D, Rognan D. Structure-based design of nonnatural ligands for the HLA-B27 protein. Journal of Receptor and Signal Transduction Research. 19: 645-57. PMID 10071790 DOI: 10.3109/10799899909036677  0.4
1999 Gonser S, Crompton NEA, Weber PJA, Beck-Sickinger AG, Folkers G. TP5 triggers signal transduction involving mitogen activated protein kinases in monocytes Journal of Receptor and Signal Transduction Research. 19: 155-166. PMID 10071755  0.4
1999 Alber F, Folkers G, Carloni P. Conformational analysis of dimethyl phosphate in aqueous solution: A density functional theory-based molecular dynamics study Journal of Molecular Structure: Theochem. 489: 237-245. DOI: 10.1016/S0166-1280(99)00057-3  0.4
1999 Gademann K, Jaun B, Seebach D, Perozzo R, Scapozza L, Folkers G. Temperature-dependent NMR and CD spectra of β-peptides: On the thermal stability of β-peptide helices - Is the folding process of β-peptides non- cooperative? Helvetica Chimica Acta. 82: 1-11. DOI: 10.1002/(SICI)1522-2675(19990113)82:1<1::AID-HLCA1>3.0.CO;2-N  0.4
1999 Muszynski IC, Scapozza L, Kovar KA, Folkers G. Quantitative structure-activity relationships of phenyltropanes as inhibitors of three monoamine transporters: Classical and CoMFA studies Quantitative Structure-Activity Relationships. 18: 342-353. DOI: 10.1002/(SICI)1521-3838(199910)18:4<342::AID-QSAR342>3.0.CO;2-E  0.4
1999 Alber F, Folkers G, Carloni P. Dimethyl Phosphate: Stereoelectronic versus Environmental Effects Journal of Physical Chemistry B. 103: 6121-6126.  0.4
1999 Eberle AN, Pliska V, Burgisser E, Folkers G. Special issue on the 8th Swiss Workshop of Methodology in Receptor Research: Preface Journal of Receptor and Signal Transduction Research. 19: xvii-xviii.  0.4
1998 Van De Waterbeemd H, Camenisch G, Folkers G, Chretien JR, Raevsky OA. Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors Journal of Drug Targeting. 6: 151-165. PMID 9886238  0.4
1998 Camenisch G, Folkers G, Van De Waterbeemd H. Shapes of membrane permeability-lipophilicity curves: Extension of theoretical models with an aqueous pore pathway European Journal of Pharmaceutical Sciences. 6: 321-329. PMID 9795090 DOI: 10.1016/S0928-0987(98)00033-5  0.4
1998 Camenisch G, Alsenz J, van de Waterbeemd H, Folkers G. Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 6: 317-324. PMID 9795088  0.4
1998 Seebach D, Poenaru S, Folkers G, Rognan D. Synthesis of Oligo(3-hydroxybutanoate)(OHB)-Containing Peptides with High Binding Affinity to a Class-I-MHC Protein Helvetica Chimica Acta. 81: 1181-1200.  0.4
1998 Scapozza L, Folkers G. Molecular mechanisms governing drug resistance of herpes simplex virus type I linked to thymidine kinase mutations International Antiviral News. 6: 210-213.  0.4
1996 Gerber S, Folkers G. A new method for quantitative determination of tritium-labeled nucleoside kinase products adsorbed on DEAE-cellulose Biochemical and Biophysical Research Communications. 225: 263-267. PMID 8769128 DOI: 10.1006/bbrc.1996.1164  0.4
1995 Greenidge PA, Merz A, Folkers G. A pseudoreceptor modelling study of the varicella-zoster virus and human thymidine kinase binding sites. Journal of Computer-Aided Molecular Design. 9: 473-8. PMID 8789189 DOI: 10.1007/BF00124318  0.4
1994 Orjala J, Wright AD, Behrends H, Folkers G, Sticher O, Rüegger H, Rali T. Cytotoxic and antibacterial dihydrochalcones from Piper aduncum. Journal of Natural Products. 57: 18-26. PMID 8158163 DOI: 10.1021/np50103a003  0.4
1986 Folkers G, Roth HJ. [The synthesis of potential 5-lipoxygenase inhibitors. 1]. Archiv Der Pharmazie. 319: 530-7. PMID 3090976 DOI: 10.1002/ardp.19863190610  0.96
1985 Folkers G, Höltje HD. Active site molecular modelling of xanthine oxidase inhibitors with antiinflammatory activity Journal of Molecular Graphics. 3: 146-150. DOI: 10.1016/0263-7855(85)80026-6  0.4
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