Jean Langhorne - Publications

Affiliations: 
Parasitology NIMR Mill Hill London 

173 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kimenyi KM, Akinyi MY, Mwikali K, Gilmore T, Mwangi S, Omer E, Gichuki B, Wambua J, Njunge J, Obiero G, Bejon P, Langhorne J, Abdi A, Ochola-Oyier LI. Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected. Bmc Infectious Diseases. 24: 140. PMID 38287287 DOI: 10.1186/s12879-024-08973-2  0.386
2023 Whiteside SK, Grant FM, Alvisi G, Clarke J, Tang L, Imianowski CJ, Zhang B, Evans AC, Wesolowski AJ, Conti AG, Yang J, Lauder SN, Clement M, Humphreys IR, Dooley J, ... ... Langhorne J, et al. Acquisition of suppressive function by conventional T cells limits antitumor immunity upon T depletion. Science Immunology. 8: eabo5558. PMID 38100544 DOI: 10.1126/sciimmunol.abo5558  0.395
2022 Tumwine-Downey I, Deroost K, Levy P, McLaughlin S, Hosking C, Langhorne J. Antibody-dependent immune responses elicited by blood stage-malaria infection contribute to protective immunity to the pre-erythrocytic stages. Current Research in Immunology. 4: 100054. PMID 36593995 DOI: 10.1016/j.crimmu.2022.100054  0.49
2022 Giorgalli M, Cunningham DA, Broncel M, Sait A, Harrison TE, Hosking C, Vandomme A, Amis SI, Antonello A, Sullivan L, Uwadiae F, Torella L, Higgins MK, Langhorne J. Differential Trafficking and Expression of PIR Proteins in Acute and Chronic Infections. Frontiers in Cellular and Infection Microbiology. 12: 877253. PMID 35782145 DOI: 10.3389/fcimb.2022.877253  0.351
2021 Deroost K, Alder C, Hosking C, McLaughlin S, Lin JW, Lewis MD, Saavedra-Torres Y, Addy JWG, Levy P, Giorgalli M, Langhorne J. Tissue macrophages and interferon-gamma signalling control blood-stage infections derived from mosquito-transmitted parasites. Current Research in Immunology. 2: 104-119. PMID 34532703 DOI: 10.1016/j.crimmu.2021.07.002  0.422
2020 Hobbs CV, Sahu T, Neal J, Conteh S, Voza T, Borkowsky W, Langhorne J, Duffy PE. Determinants of Malaria Protective Immunity in Mice Immunized with Live Sporozoites during Trimethoprim-Sulfamethoxazole Prophylaxis. The American Journal of Tropical Medicine and Hygiene. PMID 33350377 DOI: 10.4269/ajtmh.20-0749  0.368
2020 Hobbs CV, Sahu T, Neal J, Conteh S, Voza T, Borkowsky W, Langhorne J, Duffy PE. Determinants of Malaria Protective Immunity in Mice Immunized with Live Sporozoites during Trimethoprim-Sulfamethoxazole Prophylaxis. The American Journal of Tropical Medicine and Hygiene. PMID 33350377 DOI: 10.4269/ajtmh.20-0749  0.368
2020 Harrison TE, Reid AJ, Cunningham D, Langhorne J, Higgins MK. Structure of the -interspersed repeat proteins of the malaria parasite. Proceedings of the National Academy of Sciences of the United States of America. PMID 33257570 DOI: 10.1073/pnas.2016775117  0.304
2020 Harrison TE, Reid AJ, Cunningham D, Langhorne J, Higgins MK. Structure of the -interspersed repeat proteins of the malaria parasite. Proceedings of the National Academy of Sciences of the United States of America. PMID 33257570 DOI: 10.1073/pnas.2016775117  0.304
2020 Haltalli MLR, Watcham S, Wilson NK, Eilers K, Lipien A, Ang H, Birch F, Anton SG, Pirillo C, Ruivo N, Vainieri ML, Pospori C, Sinden RE, Luis TC, Langhorne J, et al. Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection. Nature Cell Biology. PMID 33230302 DOI: 10.1038/s41556-020-00601-w  0.333
2020 Haltalli MLR, Watcham S, Wilson NK, Eilers K, Lipien A, Ang H, Birch F, Anton SG, Pirillo C, Ruivo N, Vainieri ML, Pospori C, Sinden RE, Luis TC, Langhorne J, et al. Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection. Nature Cell Biology. PMID 33230302 DOI: 10.1038/s41556-020-00601-w  0.333
2020 Zhao Y, Hosking C, Cunningham D, Langhorne J, Lin JW. Transcriptome analysis of blood and spleen in virulent and avirulent mouse malaria infection. Scientific Data. 7: 253. PMID 32753619 DOI: 10.1038/s41597-020-00592-1  0.383
2020 Zhao Y, Hosking C, Cunningham D, Langhorne J, Lin JW. Transcriptome analysis of blood and spleen in virulent and avirulent mouse malaria infection. Scientific Data. 7: 253. PMID 32753619 DOI: 10.1038/s41597-020-00592-1  0.383
2020 Marr EJ, Milne RM, Anar B, Girling G, Schwach F, Mooney JP, Nahrendorf W, Spence PJ, Cunningham D, Baker DA, Langhorne J, Rayner JC, Billker O, Bushell ES, Thompson J. An enhanced toolkit for the generation of knockout and marker-free fluorescent . Wellcome Open Research. 5: 71. PMID 32500098 DOI: 10.12688/wellcomeopenres.15587.2  0.301
2020 Marr EJ, Milne RM, Anar B, Girling G, Schwach F, Mooney JP, Nahrendorf W, Spence PJ, Cunningham D, Baker DA, Langhorne J, Rayner JC, Billker O, Bushell ES, Thompson J. An enhanced toolkit for the generation of knockout and marker-free fluorescent . Wellcome Open Research. 5: 71. PMID 32500098 DOI: 10.12688/wellcomeopenres.15587.2  0.301
2020 Pérez-Mazliah D, Ndungu FM, Aye R, Langhorne J. B-cell memory in malaria: Myths and realities. Immunological Reviews. 293: 57-69. PMID 31733075 DOI: 10.1111/imr.12822  0.472
2020 Pérez-Mazliah D, Ndungu FM, Aye R, Langhorne J. B-cell memory in malaria: Myths and realities. Immunological Reviews. 293: 57-69. PMID 31733075 DOI: 10.1111/imr.12822  0.472
2020 Marr EJ, Milne RM, Anar B, Girling G, Schwach F, Mooney JP, Nahrendorf W, Spence PJ, Cunningham D, Baker DA, Langhorne J, Rayner JC, Billker O, Bushell ES, Thompson J. An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi Wellcome Open Research. 5: 71. DOI: 10.12688/wellcomeopenres.15587.1  0.3
2019 Talavera-López C, Bediako Y, Lin JW, Joseph Valletta J, Recker M, Langhorne J. Comparison of whole blood and spleen transcriptional signatures over the course of an experimental malaria infection. Scientific Reports. 9: 15853. PMID 31676877 DOI: 10.1038/s41598-019-52388-y  0.353
2019 Knackstedt SL, Georgiadou A, Apel F, Abu-Abed U, Moxon CA, Cunnington AJ, Raupach B, Cunningham D, Langhorne J, Krüger R, Barrera V, Harding SP, Berg A, Patel S, Otterdal K, et al. Neutrophil extracellular traps drive inflammatory pathogenesis in malaria. Science Immunology. 4. PMID 31628160 DOI: 10.1126/Sciimmunol.Aaw0336  0.302
2019 Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, et al. Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases. Nature Communications. 10: 2887. PMID 31253760 DOI: 10.1038/S41467-019-10601-6  0.368
2019 Gabryšová L, Alvarez-Martinez M, Luisier R, Cox LS, Sodenkamp J, Hosking C, Pérez-Mazliah D, Whicher C, Kannan Y, Potempa K, Wu X, Bhaw L, Wende H, Sieweke MH, Elgar G, ... ... Langhorne J, et al. Publisher Correction: c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4 T cells. Nature Immunology. PMID 30733606 DOI: 10.1038/S41590-019-0331-3  0.313
2019 Coelho CH, Gazzinelli-Guimaraes PH, Howard J, Barnafo E, Alani NAH, Muratova O, McCormack A, Kelnhofer E, Urban JF, Narum DL, Anderson C, Langhorne J, Nutman TB, Duffy PE. Chronic helminth infection does not impair immune response to malaria transmission blocking vaccine Pfs230D1-EPA/Alhydrogel® in mice. Vaccine. PMID 30685251 DOI: 10.1016/J.Vaccine.2019.01.027  0.373
2018 Deroost K, Langhorne J. Gamma/Delta T Cells and Their Role in Protection Against Malaria. Frontiers in Immunology. 9: 2973. PMID 30619330 DOI: 10.3389/fimmu.2018.02973  0.494
2018 Deroost K, Langhorne J. Gamma/Delta T Cells and Their Role in Protection Against Malaria. Frontiers in Immunology. 9: 2973. PMID 30619330 DOI: 10.3389/fimmu.2018.02973  0.494
2018 Talavera-López C, Capuccini B, Mitter R, Lin JW, Langhorne J. Transcriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signaling. Bmc Research Notes. 11: 913. PMID 30572937 DOI: 10.1186/s13104-018-4020-3  0.314
2018 Talavera-López C, Capuccini B, Mitter R, Lin JW, Langhorne J. Transcriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signaling. Bmc Research Notes. 11: 913. PMID 30572937 DOI: 10.1186/s13104-018-4020-3  0.314
2018 Pérez-Mazliah D, Gardner PJ, Schweighoffer E, McLaughlin S, Hosking C, Tumwine I, Davis RS, Potocnik AJ, Tybulewicz VL, Langhorne J. -specific atypical memory B cells are short-lived activated B cells. Elife. 7. PMID 30387712 DOI: 10.7554/eLife.39800  0.433
2018 Gabryšová L, Alvarez-Martinez M, Luisier R, Cox LS, Sodenkamp J, Hosking C, Pérez-Mazliah D, Whicher C, Kannan Y, Potempa K, Wu X, Bhaw L, Wende H, Sieweke MH, Elgar G, ... ... Langhorne J, et al. c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4 T cells. Nature Immunology. PMID 29662170 DOI: 10.1038/S41590-018-0083-5  0.431
2018 Lewis MD, Langhorne J. A New Link between γδ T Cells and Myeloid Cells in Malaria? Immunity. 48: 193-195. PMID 29466749 DOI: 10.1016/j.immuni.2018.02.003  0.472
2017 Pérez-Mazliah D, Nguyen MP, Hosking C, McLaughlin S, Lewis MD, Tumwine I, Levy P, Langhorne J. Follicular Helper T Cells are Essential for the Elimination of Plasmodium Infection. Ebiomedicine. PMID 28888925 DOI: 10.1016/j.ebiom.2017.08.030  0.531
2017 Moreira-Teixeira L, Redford PS, Stavropoulos E, Ghilardi N, Maynard CL, Weaver CT, Freitas do Rosário AP, Wu X, Langhorne J, O'Garra A. T Cell-Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 28584007 DOI: 10.4049/Jimmunol.1601340  0.467
2017 Cunningham DA, Lin JW, Brugat T, Jarra W, Tumwine I, Kushinga G, Ramesar J, Franke-Fayard B, Langhorne J. ICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model. Malaria Journal. 16: 185. PMID 28468674 DOI: 10.1186/s12936-017-1834-8  0.365
2017 Brugat T, Reid AJ, Lin JW, Cunningham D, Tumwine I, Kushinga G, McLaughlin S, Spence P, Böhme U, Sanders M, Conteh S, Bushell E, Metcalf T, Billker O, Duffy PE, ... ... Langhorne J, et al. Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection. Nature Microbiology. 2: 16276. PMID 28165471 DOI: 10.1038/Nmicrobiol.2016.276  0.363
2017 Lin JW, Sodenkamp J, Cunningham D, Deroost K, Tshitenge TC, McLaughlin S, Lamb TJ, Spencer-Dene B, Hosking C, Ramesar J, Janse CJ, Graham C, O'Garra A, Langhorne J. Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria. Scientific Reports. 7: 41722. PMID 28155887 DOI: 10.1038/srep41722  0.322
2017 Hobbs CV, Anderson C, Neal J, Sahu T, Conteh S, Voza T, Langhorne J, Borkowsky W, Duffy PE. Trimethoprim-Sulfamethoxazole Prophylaxis During Live Malaria Sporozoite Immunization Induces Long-Lived, Homologous, and Heterologous Protective Immunity Against Sporozoite Challenge. The Journal of Infectious Diseases. 215: 122-130. PMID 28077589 DOI: 10.1093/Infdis/Jiw482  0.35
2016 Capuccini B, Lin J, Talavera-López C, Khan SM, Sodenkamp J, Spaccapelo R, Langhorne J. Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria. Scientific Reports. 6: 39258. PMID 27991544 DOI: 10.1038/srep39258  0.4
2016 Sharma A, Conteh S, Langhorne J, Duffy PE. Heterologous Infection of Pregnant Mice Induces Low Birth Weight and Modifies Offspring Susceptibility to Malaria. Plos One. 11: e0160120. PMID 27467392 DOI: 10.1371/Journal.Pone.0160120  0.344
2016 Yam XY, Brugat T, Siau A, Lawton J, Wong DS, Farah A, Twang JS, Gao X, Langhorne J, Preiser PR. Characterization of the Plasmodium Interspersed Repeats (PIR) proteins of Plasmodium chabaudi indicates functional diversity. Scientific Reports. 6: 23449. PMID 26996203 DOI: 10.1038/srep23449  0.314
2015 Coomes SM, Pelly VS, Kannan Y, Okoye IS, Czieso S, Entwistle LJ, Perez-Lloret J, Nikolov N, Potocnik AJ, Biró J, Langhorne J, Wilson MS. IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells. Plos Pathogens. 11: e1004994. PMID 26147567 DOI: 10.1371/Journal.Ppat.1004994  0.539
2015 Pérez-Mazliah D, Ng DH, Freitas do Rosário AP, McLaughlin S, Mastelic-Gavillet B, Sodenkamp J, Kushinga G, Langhorne J. Disruption of IL-21 signaling affects T cell-B cell interactions and abrogates protective humoral immunity to malaria. Plos Pathogens. 11: e1004715. PMID 25763578 DOI: 10.1371/journal.ppat.1004715  0.557
2015 Borges da Silva H, Fonseca R, Cassado Ados A, Machado de Salles É, de Menezes MN, Langhorne J, Perez KR, Cuccovia IM, Ryffel B, Barreto VM, Marinho CR, Boscardin SB, Álvarez JM, D'Império-Lima MR, Tadokoro CE. In vivo approaches reveal a key role for DCs in CD4+ T cell activation and parasite clearance during the acute phase of experimental blood-stage malaria. Plos Pathogens. 11: e1004598. PMID 25658925 DOI: 10.1371/Journal.Ppat.1004598  0.448
2014 Perez-Mazliah D, Langhorne J. CD4 T-cell subsets in malaria: TH1/TH2 revisited. Frontiers in Immunology. 5: 671. PMID 25628621 DOI: 10.3389/fimmu.2014.00671  0.572
2014 Perez-Mazliah D, Langhorne J. CD4 T-cell subsets in malaria: TH1/TH2 revisited. Frontiers in Immunology. 5: 671. PMID 25628621 DOI: 10.3389/fimmu.2014.00671  0.572
2014 Nahrendorf W, Scholzen A, Bijker EM, Teirlinck AC, Bastiaens GJ, Schats R, Hermsen CC, Visser LG, Langhorne J, Sauerwein RW. Memory B-cell and antibody responses induced by Plasmodium falciparum sporozoite immunization. The Journal of Infectious Diseases. 210: 1981-90. PMID 24970846 DOI: 10.1093/infdis/jiu354  0.411
2014 Nahrendorf W, Scholzen A, Bijker EM, Teirlinck AC, Bastiaens GJ, Schats R, Hermsen CC, Visser LG, Langhorne J, Sauerwein RW. Memory B-cell and antibody responses induced by Plasmodium falciparum sporozoite immunization. The Journal of Infectious Diseases. 210: 1981-90. PMID 24970846 DOI: 10.1093/infdis/jiu354  0.411
2014 Brugat T, Cunningham D, Sodenkamp J, Coomes S, Wilson M, Spence PJ, Jarra W, Thompson J, Scudamore C, Langhorne J. Sequestration and histopathology in Plasmodium chabaudi malaria are influenced by the immune response in an organ-specific manner. Cellular Microbiology. 16: 687-700. PMID 24003897 DOI: 10.1111/cmi.12212  0.366
2014 Brugat T, Cunningham D, Sodenkamp J, Coomes S, Wilson M, Spence PJ, Jarra W, Thompson J, Scudamore C, Langhorne J. Sequestration and histopathology in Plasmodium chabaudi malaria are influenced by the immune response in an organ-specific manner. Cellular Microbiology. 16: 687-700. PMID 24003897 DOI: 10.1111/cmi.12212  0.366
2014 Brugat T, Cunningham D, Sodenkamp J, Coomes S, Wilson M, Spence PJ, Jarra W, Thompson J, Scudamore C, Langhorne J. Sequestration and histopathology in Plasmodium chabaudi malaria are influenced by the immune response in an organ-specific manner Cellular Microbiology. 16: 687-700. DOI: 10.1111/cmi.12212  0.365
2013 Belyaev NN, Biró J, Langhorne J, Potocnik AJ. Extramedullary myelopoiesis in malaria depends on mobilization of myeloid-restricted progenitors by IFN-γ induced chemokines. Plos Pathogens. 9: e1003406. PMID 23762028 DOI: 10.1371/journal.ppat.1003406  0.366
2013 Belyaev NN, Biró J, Langhorne J, Potocnik AJ. Extramedullary myelopoiesis in malaria depends on mobilization of myeloid-restricted progenitors by IFN-γ induced chemokines. Plos Pathogens. 9: e1003406. PMID 23762028 DOI: 10.1371/journal.ppat.1003406  0.366
2013 Roetynck S, Olotu A, Simam J, Marsh K, Stockinger B, Urban B, Langhorne J. Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure. Plos One. 8: e55195. PMID 23383106 DOI: 10.1371/journal.pone.0055195  0.432
2013 Roetynck S, Olotu A, Simam J, Marsh K, Stockinger B, Urban B, Langhorne J. Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure. Plos One. 8: e55195. PMID 23383106 DOI: 10.1371/journal.pone.0055195  0.432
2012 Spence PJ, Jarra W, Lévy P, Nahrendorf W, Langhorne J. Mosquito transmission of the rodent malaria parasite Plasmodium chabaudi Malaria Journal. 11. PMID 23217144 DOI: 10.1186/1475-2875-11-407  0.317
2012 Sponaas AM, Belyaev N, Falck-Hansen M, Potocnik A, Langhorne J. Transient deficiency of dendritic cells results in lack of a merozoite surface protein 1-specific CD4 T cell response during peak Plasmodium chabaudi blood-stage infection. Infection and Immunity. 80: 4248-56. PMID 23006847 DOI: 10.1128/IAI.00820-12  0.575
2012 Sponaas AM, Belyaev N, Falck-Hansen M, Potocnik A, Langhorne J. Transient deficiency of dendritic cells results in lack of a merozoite surface protein 1-specific CD4 T cell response during peak Plasmodium chabaudi blood-stage infection. Infection and Immunity. 80: 4248-56. PMID 23006847 DOI: 10.1128/IAI.00820-12  0.575
2012 Spence PJ, Langhorne J. T cell control of malaria pathogenesis Current Opinion in Immunology. 24: 444-448. PMID 22658628 DOI: 10.1016/j.coi.2012.05.003  0.537
2012 Mastelic B, do Rosario AP, Veldhoen M, Renauld JC, Jarra W, Sponaas AM, Roetynck S, Stockinger B, Langhorne J. IL-22 Protects Against Liver Pathology and Lethality of an Experimental Blood-Stage Malaria Infection. Frontiers in Immunology. 3: 85. PMID 22566965 DOI: 10.3389/fimmu.2012.00085  0.51
2012 Mastelic B, do Rosario AP, Veldhoen M, Renauld JC, Jarra W, Sponaas AM, Roetynck S, Stockinger B, Langhorne J. IL-22 Protects Against Liver Pathology and Lethality of an Experimental Blood-Stage Malaria Infection. Frontiers in Immunology. 3: 85. PMID 22566965 DOI: 10.3389/fimmu.2012.00085  0.51
2012 Freitas do Rosario AP, Langhorne J. T cell-derived IL-10 and its impact on the regulation of host responses during malaria. International Journal For Parasitology. 42: 549-55. PMID 22549022 DOI: 10.1016/j.ijpara.2012.03.010  0.548
2012 Freitas do Rosário AP, Lamb T, Spence P, Stephens R, Lang A, Roers A, Muller W, O'Garra A, Langhorne J. IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. Journal of Immunology (Baltimore, Md. : 1950). 188: 1178-90. PMID 22205023 DOI: 10.4049/Jimmunol.1102755  0.659
2012 Freitas do Rosário AP, Lamb T, Spence P, Stephens R, Lang A, Roers A, Muller W, O'Garra A, Langhorne J. IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. Journal of Immunology (Baltimore, Md. : 1950). 188: 1178-90. PMID 22205023 DOI: 10.4049/Jimmunol.1102755  0.659
2012 Del Portillo HA, Ferrer M, Brugat T, Martin-Jaular L, Langhorne J, Lacerda MV. The role of the spleen in malaria. Cellular Microbiology. 14: 343-55. PMID 22188297 DOI: 10.1111/j.1462-5822.2011.01741.x  0.375
2012 Del Portillo HA, Ferrer M, Brugat T, Martin-Jaular L, Langhorne J, Lacerda MV. The role of the spleen in malaria. Cellular Microbiology. 14: 343-55. PMID 22188297 DOI: 10.1111/j.1462-5822.2011.01741.x  0.375
2012 Adler G, Steeg C, Pfeffer K, Murphy TL, Murphy KM, Langhorne J, Jacobs T. B and T lymphocyte attenuator restricts the protective immune response against experimental malaria (The Journal of Immunology (2011) 187, (5310-5319)) Journal of Immunology. 188: 923. DOI: 10.4049/jimmunol.1190086  0.35
2011 Tulone C, Sponaas AM, Raiber EA, Tabor AB, Langhorne J, Chain BM. Differential requirement for cathepsin D for processing of the full length and C-terminal fragment of the malaria antigen MSP1. Plos One. 6: e24886. PMID 22053177 DOI: 10.1371/Journal.Pone.0024886  0.439
2011 Stephens R, Seddon B, Langhorne J. Homeostatic proliferation and IL-7R alpha expression do not correlate with enhanced T cell proliferation and protection in chronic mouse malaria. Plos One. 6: e26686. PMID 22039531 DOI: 10.1371/Journal.Pone.0026686  0.703
2011 Stephens R, Seddon B, Langhorne J. Homeostatic proliferation and IL-7R alpha expression do not correlate with enhanced T cell proliferation and protection in chronic mouse malaria. Plos One. 6: e26686. PMID 22039531 DOI: 10.1371/Journal.Pone.0026686  0.703
2011 Adler G, Steeg C, Pfeffer K, Murphy TL, Murphy KM, Langhorne J, Jacobs T. B and T lymphocyte attenuator restricts the protective immune response against experimental malaria. Journal of Immunology (Baltimore, Md. : 1950). 187: 5310-9. PMID 21998455 DOI: 10.4049/jimmunol.1101456  0.472
2010 Nduati EW, Ng DH, Ndungu FM, Gardner P, Urban BC, Langhorne J. Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice. Plos One. 5: e15007. PMID 21124900 DOI: 10.1371/journal.pone.0015007  0.459
2010 Nduati EW, Ng DH, Ndungu FM, Gardner P, Urban BC, Langhorne J. Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice. Plos One. 5: e15007. PMID 21124900 DOI: 10.1371/journal.pone.0015007  0.459
2010 Stephens R, Langhorne J. Effector memory Th1 CD4 T cells are maintained in a mouse model of chronic malaria. Plos Pathogens. 6: e1001208. PMID 21124875 DOI: 10.1371/Journal.Ppat.1001208  0.663
2010 Stephens R, Langhorne J. Effector memory Th1 CD4 T cells are maintained in a mouse model of chronic malaria. Plos Pathogens. 6: e1001208. PMID 21124875 DOI: 10.1371/Journal.Ppat.1001208  0.663
2010 Belyaev NN, Brown DE, Diaz AI, Rae A, Jarra W, Thompson J, Langhorne J, Potocnik AJ. Induction of an IL7-R(+)c-Kit(hi) myelolymphoid progenitor critically dependent on IFN-gamma signaling during acute malaria. Nature Immunology. 11: 477-85. PMID 20431620 DOI: 10.1038/ni.1869  0.47
2010 Fairlie-Clarke KJ, Lamb TJ, Langhorne J, Graham AL, Allen JE. Antibody isotype analysis of malaria-nematode co-infection: problems and solutions associated with cross-reactivity. Bmc Immunology. 11: 6. PMID 20163714 DOI: 10.1186/1471-2172-11-6  0.351
2010 Fairlie-Clarke KJ, Lamb TJ, Langhorne J, Graham AL, Allen JE. Antibody isotype analysis of malaria-nematode co-infection: problems and solutions associated with cross-reactivity. Bmc Immunology. 11: 6. PMID 20163714 DOI: 10.1186/1471-2172-11-6  0.351
2010 Voisine C, Mastelic B, Sponaas AM, Langhorne J. Classical CD11c+ dendritic cells, not plasmacytoid dendritic cells, induce T cell responses to Plasmodium chabaudi malaria. International Journal For Parasitology. 40: 711-9. PMID 19968996 DOI: 10.1016/j.ijpara.2009.11.005  0.5
2010 Voisine C, Mastelic B, Sponaas AM, Langhorne J. Classical CD11c+ dendritic cells, not plasmacytoid dendritic cells, induce T cell responses to Plasmodium chabaudi malaria. International Journal For Parasitology. 40: 711-9. PMID 19968996 DOI: 10.1016/j.ijpara.2009.11.005  0.5
2009 Ndungu FM, Cadman ET, Coulcher J, Nduati E, Couper E, Macdonald DW, Ng D, Langhorne J. Functional memory B cells and long-lived plasma cells are generated after a single Plasmodium chabaudi infection in mice. Plos Pathogens. 5: e1000690. PMID 20011127 DOI: 10.1371/journal.ppat.1000690  0.496
2009 Sponaas AM, Freitas do Rosario AP, Voisine C, Mastelic B, Thompson J, Koernig S, Jarra W, Renia L, Mauduit M, Potocnik AJ, Langhorne J. Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria. Blood. 114: 5522-31. PMID 19837977 DOI: 10.1182/Blood-2009-04-217489  0.474
2009 Blythe JE, Niang M, Marsh K, Holder AA, Langhorne J, Preiser PR. Characterization of the repertoire diversity of the Plasmodium falciparum stevor multigene family in laboratory and field isolates. Malaria Journal. 8: 140. PMID 19558642 DOI: 10.1186/1475-2875-8-140  0.326
2009 Cunningham D, Fonager J, Jarra W, Carret C, Preiser P, Langhorne J. Rapid changes in transcription profiles of the Plasmodium yoelii yir multigene family in clonal populations: lack of epigenetic memory? Plos One. 4: e4285. PMID 19173007 DOI: 10.1371/journal.pone.0004285  0.327
2009 Stephens R, Ndungu FM, Langhorne J. Germinal centre and marginal zone B cells expand quickly in a second Plasmodium chabaudi malaria infection producing mature plasma cells. Parasite Immunology. 31: 20-31. PMID 19121080 DOI: 10.1111/J.1365-3024.2008.01066.X  0.67
2008 Cadman ET, Abdallah AY, Voisine C, Sponaas AM, Corran P, Lamb T, Brown D, Ndungu F, Langhorne J. Alterations of splenic architecture in malaria are induced independently of Toll-like receptors 2, 4, and 9 or MyD88 and may affect antibody affinity. Infection and Immunity. 76: 3924-31. PMID 18559428 DOI: 10.1128/IAI.00372-08  0.384
2008 Cadman ET, Abdallah AY, Voisine C, Sponaas AM, Corran P, Lamb T, Brown D, Ndungu F, Langhorne J. Alterations of splenic architecture in malaria are induced independently of Toll-like receptors 2, 4, and 9 or MyD88 and may affect antibody affinity. Infection and Immunity. 76: 3924-31. PMID 18559428 DOI: 10.1128/IAI.00372-08  0.384
2008 Blythe JE, Yam XY, Kuss C, Bozdech Z, Holder AA, Marsh K, Langhorne J, Preiser PR. Plasmodium falciparum STEVOR proteins are highly expressed in patient isolates and located in the surface membranes of infected red blood cells and the apical tips of merozoites. Infection and Immunity. 76: 3329-36. PMID 18474651 DOI: 10.1128/IAI.01460-07  0.309
2008 Lamb TJ, Langhorne J. The severity of malarial anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently of the number of circulating parasites. Malaria Journal. 7: 68. PMID 18439291 DOI: 10.1186/1475-2875-7-68  0.408
2008 Lamb TJ, Langhorne J. The severity of malarial anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently of the number of circulating parasites. Malaria Journal. 7: 68. PMID 18439291 DOI: 10.1186/1475-2875-7-68  0.408
2007 Achtman AH, Stephens R, Cadman ET, Harrison V, Langhorne J. Malaria-specific antibody responses and parasite persistence after infection of mice with Plasmodium chabaudi chabaudi. Parasite Immunology. 29: 435-444. PMID 17727567 DOI: 10.1111/J.1365-3024.2007.00960.X  0.627
2007 Fonseca L, Seixas E, Butcher G, Langhorne J. Cytokine responses of CD4+ T cells during a Plasmodium chabaudi chabaudi (ER) blood-stage infection in mice initiated by the natural route of infection. Malaria Journal. 6: 77. PMID 17555592 DOI: 10.1186/1475-2875-6-77  0.48
2007 Lamb TJ, Voisine C, Koernig S, Egan CA, Harnett W, Langhorne J. The pathology of Plasmodium chabaudi infection is not ameliorated by the secreted filarial nematode immunomodulatory molecule, ES-62 Parasite Immunology. 29: 271-276. PMID 17430551 DOI: 10.1111/j.1365-3024.2007.00941.x  0.397
2007 Lepenies B, Gaworski I, Tartz S, Langhorne J, Fleischer B, Jacobs T. CTLA-4 blockade differentially influences the outcome of non-lethal and lethal Plasmodium yoelii infections. Microbes and Infection / Institut Pasteur. 9: 687-94. PMID 17398134 DOI: 10.1016/j.micinf.2007.02.013  0.439
2007 Lamikanra AA, Brown D, Potocnik A, Casals-Pascual C, Langhorne J, Roberts DJ. Malarial anemia: of mice and men. Blood. 110: 18-28. PMID 17341664 DOI: 10.1182/blood-2006-09-018069  0.321
2007 Lamikanra AA, Brown D, Potocnik A, Casals-Pascual C, Langhorne J, Roberts DJ. Malarial anemia: of mice and men. Blood. 110: 18-28. PMID 17341664 DOI: 10.1182/blood-2006-09-018069  0.321
2006 Sponaas AM, Cadman ET, Voisine C, Harrison V, Boonstra A, O'Garra A, Langhorne J. Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells. The Journal of Experimental Medicine. 203: 1427-33. PMID 16754719 DOI: 10.1084/jem.20052450  0.518
2006 Sponaas AM, Cadman ET, Voisine C, Harrison V, Boonstra A, O'Garra A, Langhorne J. Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells. The Journal of Experimental Medicine. 203: 1427-33. PMID 16754719 DOI: 10.1084/jem.20052450  0.518
2006 Ndungu FM, Sanni L, Urban B, Stephens R, Newbold CI, Marsh K, Langhorne J. CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway. Journal of Immunology (Baltimore, Md. : 1950). 176: 5504-12. PMID 16622019 DOI: 10.4049/Jimmunol.176.9.5504  0.66
2006 Ndungu FM, Sanni L, Urban B, Stephens R, Newbold CI, Marsh K, Langhorne J. CD4 T cells from malaria-nonexposed individuals respond to the CD36-Binding Domain of Plasmodium falciparum erythrocyte membrane protein-1 via an MHC class II-TCR-independent pathway. Journal of Immunology (Baltimore, Md. : 1950). 176: 5504-12. PMID 16622019 DOI: 10.4049/Jimmunol.176.9.5504  0.66
2006 Stephens R, Langhorne J. Priming of CD4+ T cells and development of CD4+ T cell memory; lessons for malaria Parasite Immunology. 28: 25-30. PMID 16438673 DOI: 10.1111/J.1365-3024.2006.00767.X  0.687
2005 Tongren JE, Corran PH, Jarra W, Langhorne J, Riley EM. Epitope-specific regulation of immunoglobulin class switching in mice immunized with malarial merozoite surface proteins Infection and Immunity. 73: 8119-8129. PMID 16299306 DOI: 10.1128/IAI.73.12.8119-8129.2005  0.303
2005 Achtman AH, Bull PC, Stephens R, Langhorne J. Longevity of the Immune Response and Memory to Blood-Stage Malaria Infection Current Topics in Microbiology and Immunology. 297: 71-102. PMID 16265903 DOI: 10.1007/3-540-29967-X_3  0.639
2005 Cunningham DA, Jarra W, Koernig S, Fonager J, Fernandez-Reyes D, Blythe JE, Waller C, Preiser PR, Langhorne J. Host immunity modulates transcriptional changes in a multigene family (yir) of rodent malaria. Molecular Microbiology. 58: 636-47. PMID 16238615 DOI: 10.1111/j.1365-2958.2005.04840.x  0.34
2005 Ndungu FM, Urban BC, Marsh K, Langhorne J. Regulation of immune response by Plasmodium-infected red blood cells. Parasite Immunology. 27: 373-84. PMID 16179031 DOI: 10.1111/j.1365-3024.2005.00771.x  0.437
2005 Stephens R, Albano FR, Quin S, Pascal BJ, Harrison V, Stockinger B, Kioussis D, Weltzien HU, Langhorne J. Malaria-specific transgenic CD4(+) T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance. Blood. 106: 1676-84. PMID 15890689 DOI: 10.1182/Blood-2004-10-4047  0.707
2005 Stephens R, Albano FR, Quin S, Pascal BJ, Harrison V, Stockinger B, Kioussis D, Weltzien HU, Langhorne J. Malaria-specific transgenic CD4(+) T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance. Blood. 106: 1676-84. PMID 15890689 DOI: 10.1182/Blood-2004-10-4047  0.707
2005 Dorfman JR, Bejon P, Ndungu FM, Langhorne J, Kortok MM, Lowe BS, Mwangi TW, Williams TN, Marsh K. B cell memory to 3 Plasmodium falciparum blood-stage antigens in a malaria-endemic area. The Journal of Infectious Diseases. 191: 1623-30. PMID 15838788 DOI: 10.1086/429671  0.38
2005 Langhorne J. The role of CD4+ T-cells in the immune response to Plasmodium chabaudi. Parasitology Today (Personal Ed.). 5: 362-4. PMID 15463156 DOI: 10.1016/0169-4758(89)90113-0  0.472
2005 Langhorne J. gammadelta T cells in malaria infections. Parasitology Today (Personal Ed.). 12: 200-3. PMID 15275215 DOI: 10.1016/0169-4758(96)10009-0  0.504
2004 Langhorne J, Albano FR, Hensmann M, Sanni L, Cadman E, Voisine C, Sponaas AM. Dendritic cells, pro-inflammatory responses, and antigen presentation in a rodent malaria infection Immunological Reviews. 201: 35-47. PMID 15361231 DOI: 10.1111/j.0105-2896.2004.00182.x  0.532
2004 Sanni LA, Jarra W, Li C, Langhorne J. Cerebral edema and cerebral hemorrhages in interleukin-10-deficient mice infected with Plasmodium chabaudi. Infection and Immunity. 72: 3054-8. PMID 15102820 DOI: 10.1128/IAI.72.5.3054-3058.2004  0.333
2004 Sanni LA, Jarra W, Li C, Langhorne J. Cerebral edema and cerebral hemorrhages in interleukin-10-deficient mice infected with Plasmodium chabaudi. Infection and Immunity. 72: 3054-8. PMID 15102820 DOI: 10.1128/IAI.72.5.3054-3058.2004  0.333
2004 Hensmann M, Li C, Moss C, Lindo V, Greer F, Watts C, Ogun SA, Holder AA, Langhorne J. Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response. European Journal of Immunology. 34: 639-48. PMID 14991593 DOI: 10.1002/eji.200324514  0.435
2003 Li C, Sanni LA, Omer F, Riley E, Langhorne J. Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies. Infection and Immunity. 71: 4850-6. PMID 12933825 DOI: 10.1128/IAI.71.9.4850-4856.2003  0.334
2003 Li C, Sanni LA, Omer F, Riley E, Langhorne J. Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies. Infection and Immunity. 71: 4850-6. PMID 12933825 DOI: 10.1128/IAI.71.9.4850-4856.2003  0.334
2003 Achtman AH, Khan M, MacLennan IC, Langhorne J. Plasmodium chabaudi chabaudi infection in mice induces strong B cell responses and striking but temporary changes in splenic cell distribution. Journal of Immunology (Baltimore, Md. : 1950). 171: 317-24. PMID 12817013 DOI: 10.4049/jimmunol.171.1.317  0.395
2003 Achtman AH, Khan M, MacLennan IC, Langhorne J. Plasmodium chabaudi chabaudi infection in mice induces strong B cell responses and striking but temporary changes in splenic cell distribution. Journal of Immunology (Baltimore, Md. : 1950). 171: 317-24. PMID 12817013 DOI: 10.4049/jimmunol.171.1.317  0.395
2002 Seixas E, Langhorne J, Quin S. Limiting dilution analysis of antigen-specific CD4+ T-cell responses in mice. Methods in Molecular Medicine. 72: 385-99. PMID 12125134 DOI: 10.1385/1-59259-271-6:385  0.427
2002 Seixas E, Langhorne J, Quin S. Limiting dilution analysis of antigen-specific CD4+ T-cell responses in mice. Methods in Molecular Medicine. 72: 385-99. PMID 12125134 DOI: 10.1385/1-59259-271-6:385  0.427
2002 Langhorne J, Quin SJ, Sanni LA. Mouse models of blood-stage malaria infections: immune responses and cytokines involved in protection and pathology. Chemical Immunology. 80: 204-28. PMID 12058640 DOI: 10.1159/000058845  0.387
2002 Langhorne J, Quin SJ, Sanni LA. Mouse models of blood-stage malaria infections: immune responses and cytokines involved in protection and pathology. Chemical Immunology. 80: 204-28. PMID 12058640 DOI: 10.1159/000058845  0.387
2002 Sanni LA, Allsopp CE, Reubsaet L, Sanni A, Newbold C, Chauhan VS, Langhorne J. Cellular responses to Plasmodium falciparum erythrocyte membrane protein-1: use of relatively conserved synthetic peptide pools to determine CD4 T cell responses in malaria-exposed individuals in Benin, West Africa. Malaria Journal. 1: 7. PMID 12057026 DOI: 10.1186/1475-2875-1-7  0.416
2002 Seixas E, Fonseca L, Langhorne J. The influence of gammadelta T cells on the CD4+ T cell and antibody response during a primary Plasmodium chabaudi chabaudi infection in mice. Parasite Immunology. 24: 131-40. PMID 11982858 DOI: 10.1046/j.1365-3024.2002.00446.x  0.596
2002 Allsopp CE, Sanni LA, Reubsaet L, Ndungu F, Newbold C, Mwangi T, Marsh K, Langhorne J. CD4 T cell responses to a variant antigen of the malaria parasite Plasmodium falciparum, erythrocyte membrane protein-1, in individuals living in malaria-endemic areas. The Journal of Infectious Diseases. 185: 812-9. PMID 11920299 DOI: 10.1086/339521  0.509
2001 Seixas E, Cross C, Quin S, Langhorne J. Direct activation of dendritic cells by the malaria parasite, Plasmodium chabaudi chabaudi. European Journal of Immunology. 31: 2970-8. PMID 11592073 DOI: 10.1002/1521-4141(2001010)31:10<2970::AID-IMMU2970>3.0.CO;2-S  0.455
2001 Li C, Seixas E, Langhorne J. Rodent malarias: the mouse as a model for understanding immune responses and pathology induced by the erythrocytic stages of the parasite. Medical Microbiology and Immunology. 189: 115-26. PMID 11388608 DOI: 10.1007/s430-001-8017-8  0.303
2001 Taylor PR, Seixas E, Walport MJ, Langhorne J, Botto M. Complement contributes to protective immunity against reinfection by Plasmodium chabaudi chabaudi parasites. Infection and Immunity. 69: 3853-9. PMID 11349051 DOI: 10.1128/IAI.69.6.3853-3859.2001  0.431
2001 Freitag C, Chougnet C, Schito M, Near KA, Shearer GM, Li C, Langhorne J, Sher A. Malaria infection induces virus expression in human immunodeficiency virus transgenic mice by CD4 T cell-dependent immune activation. The Journal of Infectious Diseases. 183: 1260-8. PMID 11262209 DOI: 10.1086/319686  0.448
2001 Quin SJ, Langhorne J. Different regions of the malaria merozoite surface protein 1 of Plasmodium chabaudi elicit distinct T-cell and antibody isotype responses. Infection and Immunity. 69: 2245-51. PMID 11254580 DOI: 10.1128/IAI.69.4.2245-2251.2001  0.521
2001 Quin SJ, Seixas EM, Cross CA, Berg M, Lindo V, Stockinger B, Langhorne J. Low CD4(+) T cell responses to the C-terminal region of the malaria merozoite surface protein-1 may be attributed to processing within distinct MHC class II pathways. European Journal of Immunology. 31: 72-81. PMID 11169440 DOI: 10.1002/1521-4141(200101)31:1<72::AID-IMMU72>3.0.CO;2-Z  0.369
2000 Li C, Langhorne J. Tumor necrosis factor alpha p55 receptor is important for development of memory responses to blood-stage malaria infection. Infection and Immunity. 68: 5724-30. PMID 10992477 DOI: 10.1128/IAI.68.10.5724-5730.2000  0.386
1999 Li C, Corraliza I, Langhorne J. A defect in interleukin-10 leads to enhanced malarial disease in Plasmodium chabaudi chabaudi infection in mice. Infection and Immunity. 67: 4435-42. PMID 10456884 DOI: 10.1128/IAI.67.9.4435-4442.1999  0.321
1999 Maizels R, Langhorne J, Glaichenhaus N. Pathogenic and protective responses in parasitic infections. Research in Immunology. 149: 875-7. PMID 9923646 DOI: 10.1016/S0923-2494(99)80018-2  0.387
1998 Cross CE, Langhorne J. Plasmodium chabaudi chabaudi (AS): inflammatory cytokines and pathology in an erythrocytic-stage infection in mice. Experimental Parasitology. 90: 220-9. PMID 9806866 DOI: 10.1006/expr.1998.4335  0.304
1998 Allsopp CE, Nicholls SJ, Langhorne J. A flow cytometric method to assess antigen-specific proliferative responses of different subpopulations of fresh and cryopreserved human peripheral blood mononuclear cells. Journal of Immunological Methods. 214: 175-86. PMID 9692869 DOI: 10.1016/S0022-1759(98)00056-8  0.314
1998 Langhorne J, Cross C, Seixas E, Li C, von der Weid T. A role for B cells in the development of T cell helper function in a malaria infection in mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 1730-4. PMID 9465085 DOI: 10.1073/PNAS.95.4.1730  0.5
1997 Berg M, Uellner R, Langhorne J. Fc gamma receptor II dependency of enhanced presentation of major histocompatibility complex class II peptides by a B cell lymphoma. European Journal of Immunology. 27: 1022-8. PMID 9130659 DOI: 10.1002/EJI.1830270432  0.312
1997 Jones SM, Goodier MR, Langhorne J. The response of gamma delta T cells to Plasmodium falciparum is dependent on activated CD4+ T cells and the recognition of MHC class I molecules. Immunology. 89: 405-12. PMID 8958054 DOI: 10.1046/j.1365-2567.1996.d01-762.x  0.464
1996 Linke A, Kühn R, Müller W, Honarvar N, Li C, Langhorne J. Plasmodium chabaudi chabaudi: differential susceptibility of gene-targeted mice deficient in IL-10 to an erythrocytic-stage infection. Experimental Parasitology. 84: 253-63. PMID 8932775 DOI: 10.1006/expr.1996.0111  0.418
1996 Goodier MR, Lundqvist C, Hammarström ML, Troye-Blomberg M, Langhorne J. Cytokine profiles for human V gamma 9+ T cells stimulated by Plasmodium falciparum. Parasite Immunology. 17: 413-23. PMID 7501422 DOI: 10.1111/j.1365-3024.1995.tb00909.x  0.372
1995 Langhorne J. The immune response to the blood stages of Plasmodium in animal models. Immunology Letters. 41: 99-102. PMID 8002055 DOI: 10.1016/0165-2478(94)90115-5  0.424
1995 Langhorne J, Morris-Jones S, Casabo LG, Goodier M. The response of gamma delta T cells in malaria infections: a hypothesis. Research in Immunology. 145: 429-36. PMID 7899708 DOI: 10.1016/S0923-2494(94)80173-8  0.479
1995 von der Weid T, Kitamura D, Rajewsky K, Langhorne J. A dual role for B cells in Plasmodium chabaudi chabaudi (AS) infection? Research in Immunology. 145: 412-9. PMID 7899705 DOI: 10.1016/S0923-2494(94)80170-3  0.463
1995 Langhorne J, Mombaerts P, Tonegawa S. alpha beta and gamma delta T cells in the immune response to the erythrocytic stages of malaria in mice. International Immunology. 7: 1005-11. PMID 7577794 DOI: 10.1093/intimm/7.6.1005  0.413
1994 von der Weid T, Langhorne J. Altered response of CD4+ T cell subsets to Plasmodium chabaudi chabaudi in B cell-deficient mice. International Immunology. 5: 1343-8. PMID 8268139 DOI: 10.1093/INTIMM/5.10.1343  0.49
1994 von der Weid T, Langhorne J. The roles of cytokines produced in the immune response to the erythrocytic stages of mouse malarias. Immunobiology. 189: 397-418. PMID 8125518 DOI: 10.1016/S0171-2985(11)80367-0  0.502
1994 Hartz D, Langhorne J. Immunization of mice with Escherichia coli containing an antigen of the malaria parasite Plasmodium chabaudi chabaudi expressed in λgt11 induces high antibody titres Immunology Letters. 41: 217-223. PMID 8002041 DOI: 10.1016/0165-2478(94)90136-8  0.341
1994 Weid Tvd, Kopf M, Köhler G, Langhorne J. The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice. European Journal of Immunology. 24: 2285-2293. PMID 7925557 DOI: 10.1002/Eji.1830241004  0.446
1994 Good M, Langhorne J. T-cell immunity to malaria Research in Immunology. 145: 405. DOI: 10.1016/S0923-2494(94)80168-1  0.401
1993 Goodier M, Krause-Jauer M, Sanni A, Massougbodji A, Sadeler BC, Mitchell GH, Modolell M, Eichmann K, Langhorne J. Gamma delta T cells in the peripheral blood of individuals from an area of holoendemic Plasmodium falciparum transmission. Transactions of the Royal Society of Tropical Medicine and Hygiene. 87: 692-6. PMID 8296383 DOI: 10.1016/0035-9203(93)90299-6  0.416
1993 Langhorne J, Pells S, Eichmann K. Phenotypic characterization of splenic T cells from mice infected with Plasmodium chabaudi chabaudi. Scandinavian Journal of Immunology. 38: 521-8. PMID 8256109 DOI: 10.1111/J.1365-3083.1993.Tb03235.X  0.447
1992 Goodier M, Fey P, Eichmann K, Langhorne J. Human peripheral blood gamma delta T cells respond to antigens of Plasmodium falciparum. International Immunology. 4: 33-41. PMID 1531764 DOI: 10.1093/Intimm/4.1.33  0.493
1992 Goodier M, Krause-Jauer M, Langhorne J. Quantitative analysis of the response of human T cell receptor V gamma 9+ cells to Plasmodium falciparum. European Journal of Immunology. 22: 2757-60. PMID 1396980 DOI: 10.1002/EJI.1830221045  0.375
1992 Langhorne J, Goodier M, Behr C, Dubois P. Is there a role for gamma delta T cells in malaria? Immunology Today. 13: 298-300. PMID 1387316 DOI: 10.1016/0167-5699(92)90041-5  0.373
1991 Langhorne J, Simon-Haarhaus B, Meding SJ. The role of CD4+ T cells in the protective immune response to Plasmodium chabaudi in vivo. Immunology Letters. 25: 101-7. PMID 1980906 DOI: 10.1016/0165-2478(90)90099-C  0.526
1991 Freudenberg MA, Kumazawa Y, Meding S, Langhorne J, Galanos C. Gamma interferon production in endotoxin-responder and -nonresponder mice during infection. Infection and Immunity. 59: 3484-91. PMID 1910003 DOI: 10.1128/iai.59.10.3484-3491.1991  0.339
1991 Meding SJ, Langhorne J. CD4+ T cells and B cells are necessary for the transfer of protective immunity to Plasmodium chabaudi chabaudi. European Journal of Immunology. 21: 1433-8. PMID 1675172 DOI: 10.1002/EJI.1830210616  0.498
1991 Langhorne J. Current topics in microbiology and immunology: T cell paradigms in parasitic and bacterial infections Vol. 155 Parasitology Today. 7: 128. DOI: 10.1016/0169-4758(91)90181-M  0.452
1990 Slade SJ, Langhorne J. Production of interferon-gamma during infection of mice with Plasmodium chabaudi chabaudi. Immunobiology. 179: 353-65. PMID 2515153 DOI: 10.1016/S0171-2985(89)80041-5  0.365
1990 Wirbelauer C, Meding S, Stockinger B, Gillard S, Langhorne J. Analysis of T lymphocyte reactivity to complex antigen mixtures by the use of proteins coupled to latex beads. Immunology Letters. 23: 257-62. PMID 2189827 DOI: 10.1016/0165-2478(90)90069-3  0.337
1990 Meding SJ, Cheng SC, Simon-Haarhaus B, Langhorne J. Role of gamma interferon during infection with Plasmodium chabaudi chabaudi. Infection and Immunity. 58: 3671-8. PMID 1977706 DOI: 10.1128/iai.58.11.3671-3678.1990  0.421
1989 Langhorne J, Meding SJ, Eichmann K, Gillard SS. The response of CD4+ T cells to Plasmodium chabaudi chabaudi. Immunological Reviews. 112: 71-94. PMID 2575075 DOI: 10.1111/J.1600-065X.1989.Tb00553.X  0.586
1989 Langhorne J, Simon B. Limiting dilution analysis of the T cell response to Plasmodium chabaudi chabaudi in mice. Parasite Immunology. 11: 545-59. PMID 2573876 DOI: 10.1111/j.1365-3024.1989.tb00688.x  0.487
1989 Langhorne J, Gillard S, Simon B, Slade S, Eichmann K. Frequencies of CD4+ T cells reactive with Plasmodium chabaudi chabaudi: distinct response kinetics for cells with Th1 and Th2 characteristics during infection. International Immunology. 1: 416-24. PMID 2535135 DOI: 10.1093/Intimm/1.4.416  0.538
1989 Lamers MC, Vakil M, Kearney JF, Langhorne J, Paige CJ, Julius MH, Mossmann H, Carsetti R, Köhler G. Immune status of a mu, kappa transgenic mouse line. Deficient response to bacterially related antigens. European Journal of Immunology. 19: 459-68. PMID 2468503 DOI: 10.1002/Eji.1830190308  0.318
1988 Langhorne J, Asofsky R. Influence of Plasmodium chabaudi adami on the isotypic distribution of the antibody response of mice to sheep erythrocytes. Immunobiology. 174: 432-43. PMID 3315975 DOI: 10.1016/S0171-2985(87)80016-5  0.33
1988 Julius MH, Rammensee H, Ratcliffe MJH, Lamers MC, Langhorne J, Köhler G. The molecular interactions with helper T cells which limit antigen-specific B cell differentiation European Journal of Immunology. 18: 381-386. PMID 2965645 DOI: 10.1002/Eji.1830180310  0.357
1988 Langhorne J, Titus JA. Expression of Fc(γ) receptors on splenic T cells of mice infected with Plasmodium chabaudi adami European Journal of Immunology. 18: 1-6. PMID 2964371 DOI: 10.1002/EJI.1830180102  0.426
1988 Süss G, Eichmann K, Kury E, Linke A, Langhorne J. Roles of CD4- and CD8-bearing T lymphocytes in the immune response to the erythrocytic stages of Plasmodium chabaudi. Infection and Immunity. 56: 3081-8. PMID 2903123 DOI: 10.1128/Iai.56.12.3081-3088.1988  0.471
1987 Rammensee HG, Julius MH, Nemazee D, Langhorne J, Lamers R, Köhler G. Targeting cytotoxic T cells to antigen-specific B lymphocytes. European Journal of Immunology. 17: 433-6. PMID 3494614 DOI: 10.1002/Eji.1830170322  0.331
1985 Langhorne J, Kim KJ, Asofsky R. Distribution of immunoglobulin isotypes in the nonspecific B-cell response induced by infection with Plasmodium chabaudi adami and Plasmodium yoelii. Cellular Immunology. 90: 251-7. PMID 3881190 DOI: 10.1016/0008-8749(85)90187-X  0.471
1984 Langhorne J, Evans CB, Asofsky R, Taylor DW. Immunoglobulin isotype distribution of malaria-specific antibodies produced during infection with Plasmodium chabaudi adami and Plasmodium yoelii Cellular Immunology. 87: 452-461. PMID 6467384 DOI: 10.1016/0008-8749(84)90014-5  0.36
1983 Langhorne J, Rollwagen FM, Finerty JF. Induction of T cell activity in athymic (nu/nu) mice infected with Trypanosoma rhodesiense. Cellular Immunology. 81: 180-6. PMID 6225524 DOI: 10.1016/0008-8749(83)90224-1  0.393
1979 Langhorne J, Cohen S. Plasmodium knowlesi in the marmoset (Callithrix jacchus). Parasitology. 78: 67-76. PMID 33359 DOI: 10.1017/S0031182000048599  0.301
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