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Ute A Hellmich, Ph.D. - Publications

Affiliations: 
2015-2020 Chemistry Johannes Gutenberg-University Mainz, Germany 
 2021- Institute of Organic Chemistry & Macromolecular Chemistry (IOMC) Friedrich-Schiller-University Jena, Jena, Thüringen, Germany 
Website:
https://www.hellmich-group.de/current-team/ute-a-hellmich/
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Berth SH, Vo L, Kwon DH, Grider T, Damayanti YS, Kosmanopoulos G, Fox A, Lau AR, Carr P, Donohue JK, Hoke M, Thomas S, Karim C, Fay AJ, Meltzer E, ... ... Hellmich UA, et al. Combined clinical, structural, and cellular studies discriminate pathogenic and benign TRPV4 variants. Brain : a Journal of Neurology. PMID 39021275 DOI: 10.1093/brain/awae243  0.543
2023 Catalina-Hernández È, López-Martín M, Masnou-Sánchez D, Martins M, Lorenz-Fonfria VA, Jiménez-Altayó F, Hellmich UA, Inada H, Alcaraz A, Furutani Y, Nonell-Canals A, Vázquez-Ibar JL, Domene C, Gaudet R, Perálvarez-Marín A. Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold. Computational and Structural Biotechnology Journal. 23: 473-482. PMID 38261868 DOI: 10.1016/j.csbj.2023.12.028  0.57
2023 Goretzki B, Wiedemann C, McCray BA, Schäfer SL, Jansen J, Tebbe F, Mitrovic SA, Nöth J, Cabezudo AC, Donohue JK, Jeffries CM, Steinchen W, Stengel F, Sumner CJ, Hummer G, ... Hellmich UA, et al. Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity. Nature Communications. 14: 4165. PMID 37443299 DOI: 10.1038/s41467-023-39808-4  0.341
2022 Zhang L, Simonsen C, Zimova L, Wang K, Moparthi L, Gaudet R, Ekoff M, Nilsson G, Hellmich UA, Vlachova V, Gourdon P, Zygmunt PM. Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function. Nature Communications. 13: 7483. PMID 36470868 DOI: 10.1038/s41467-022-35163-y  0.557
2022 Pérez Carrillo VH, Rose-Sperling D, Tran MA, Wiedemann C, Hellmich UA. Backbone NMR assignment of the nucleotide binding domain of the Bacillus subtilis ABC multidrug transporter BmrA in the post-hydrolysis state. Biomolecular Nmr Assignments. PMID 34988902 DOI: 10.1007/s12104-021-10063-2  0.444
2020 Ford RC, Hellmich UA. What monomeric nucleotide binding domains can teach us about dimeric ABC proteins. Febs Letters. PMID 32880928 DOI: 10.1002/1873-3468.13921  0.419
2018 Rose-Sperling D, Tran MA, Lauth LM, Goretzki B, Hellmich UA. 19F NMR as a versatile tool to study (membrane) protein structure and dynamics. Biological Chemistry. PMID 31004560 DOI: 10.1515/hsz-2018-0473  0.349
2018 Goretzki B, Glogowski NA, Diehl E, Duchardt-Ferner E, Hacker C, Gaudet R, Hellmich UA. Structural Basis of TRPV4 N Terminus Interaction with Syndapin/PACSIN1-3 and PIP. Structure (London, England : 1993). PMID 30244966 DOI: 10.1016/J.Str.2018.08.002  0.593
2017 Szöllősi D, Rose-Sperling D, Hellmich UA, Stockner T. Comparison of mechanistic transport cycle models of ABC exporters. Biochimica Et Biophysica Acta. PMID 29097275 DOI: 10.1016/j.bbamem.2017.10.028  0.387
2017 Neumann J, Rose-Sperling D, Hellmich UA. Diverse relations between ABC transporters and lipids: An overview. Biochimica Et Biophysica Acta. Biomembranes. 1859: 605-618. PMID 27693344 DOI: 10.1016/j.bbamem.2016.09.023  0.318
2015 Hellmich UA, Mönkemeyer L, Velamakanni S, van Veen HW, Glaubitz C. Effects of nucleotide binding to LmrA: A combined MAS-NMR and solution NMR study. Biochimica Et Biophysica Acta. 1848: 3158-65. PMID 26449340 DOI: 10.1016/j.bbamem.2015.10.003  0.65
2014 Hellmich UA, Gaudet R. High-resolution views of TRPV1 and their implications for the TRP channel superfamily. Handbook of Experimental Pharmacology. 223: 991-1004. PMID 24961977 DOI: 10.1007/978-3-319-05161-1_11  0.556
2014 Hellmich UA, Gaudet R. Structural biology of TRP channels. Handbook of Experimental Pharmacology. 223: 963-90. PMID 24961976 DOI: 10.1007/978-3-319-05161-1_10  0.568
2013 Garcia-Elias A, Mrkonjic S, Pardo-Pastor C, Inada H, Hellmich UA, Rubio-Moscardó F, Plata C, Gaudet R, Vicente R, Valverde MA. Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli. Proceedings of the National Academy of Sciences of the United States of America. 110: 9553-8. PMID 23690576 DOI: 10.1073/Pnas.1220231110  0.588
2013 Mörs K, Hellmich UA, Basting D, Marchand P, Wurm JP, Haase W, Glaubitz C. A lipid-dependent link between activity and oligomerization state of the M. tuberculosis SMR protein TBsmr. Biochimica Et Biophysica Acta. 1828: 561-7. PMID 23103507 DOI: 10.1016/j.bbamem.2012.10.020  0.596
2012 Hellmich UA, Lyubenova S, Kaltenborn E, Doshi R, Van Veen HW, Prisner TF, Glaubitz C. Probing the ATP hydrolysis cycle of the abc multidrug transporter LmrA by pulsed EPR spectroscopy Journal of the American Chemical Society. 134: 5857-5862. PMID 22397466 DOI: 10.1021/Ja211007T  0.648
2012 Hellmich UA, Duchardt-Ferner E, Glaubitz C, Wöhnert J. Backbone NMR resonance assignments of the nucleotide binding domain of the ABC multidrug transporter LmrA from Lactococcus lactis in its ADP-bound state. Biomolecular Nmr Assignments. 6: 69-73. PMID 21786024 DOI: 10.1007/s12104-011-9327-0  0.634
2011 Ullrich SJ, Hellmich UA, Ullrich S, Glaubitz C. Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR. Nature Chemical Biology. 7: 263-70. PMID 21423170 DOI: 10.1038/nchembio.543  0.579
2011 Zutz A, Hoffmann J, Hellmich UA, Glaubitz C, Ludwig B, Brutschy B, Tampé R. Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus. The Journal of Biological Chemistry. 286: 7104-15. PMID 21190941 DOI: 10.1074/jbc.M110.201178  0.593
2009 Hellmich UA, Glaubitz C. NMR and EPR studies of membrane transporters. Biological Chemistry. 390: 815-34. PMID 19453273 DOI: 10.1515/BC.2009.084  0.615
2009 Pfleger N, Wörner AC, Yang J, Shastri S, Hellmich UA, Aslimovska L, Maier MS, Glaubitz C. Solid-state NMR and functional studies on proteorhodopsin. Biochimica Et Biophysica Acta. 1787: 697-705. PMID 19268651 DOI: 10.1016/j.bbabio.2009.02.022  0.552
2009 Hellmich UA, Pfleger N, Glaubitz C. F-MAS NMR on proteorhodopsin: enhanced protocol for site-specific labeling for general application to membrane proteins. Photochemistry and Photobiology. 85: 535-9. PMID 19192211 DOI: 10.1111/j.1751-1097.2008.00498.x  0.578
2009 Hellmich UA, Lyubenova S, Moenkemeyer L, Kaltenborn E, Veen HWv, Prisner T, Glaubitz C. Investigation Of The Multidrug ABC-transporter LmrA By Multinuclear MAS-NMR And EPR Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.3169  0.614
2009 Wollschlag SJ, Hellmich UA, Glaubitz C. Real Time 31P and Steady State 19F/13C Solid State NMR on Integral Membrane Protein E.coli Diacylglycerol Kinase Biophysical Journal. 96: 393a. DOI: 10.1016/j.bpj.2008.12.2928  0.548
2008 Hellmich UA, Haase W, Velamakanni S, van Veen HW, Glaubitz C. Caught in the act: ATP hydrolysis of an ABC-multidrug transporter followed by real-time magic angle spinning NMR. Febs Letters. 582: 3557-62. PMID 18817774 DOI: 10.1016/j.febslet.2008.09.033  0.613
2007 Siarheyeva A, Lopez JJ, Lehner I, Hellmich UA, van Veen HW, Glaubitz C. Probing the molecular dynamics of the ABC multidrug transporter LmrA by deuterium solid-state nuclear magnetic resonance. Biochemistry. 46: 3075-83. PMID 17302438 DOI: 10.1021/bi062109a  0.63
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