Jack Taunton - Publications

Affiliations: 
Cellular and Molecular Pharmacology University of California, San Francisco, San Francisco, CA 
Area:
signaling proteins
Website:
http://www.hhmi.org/scientists/jack-taunton

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lam C, Ferguson ID, Mariano MC, Lin YT, Murnane M, Liu H, Smith GA, Wong SW, Taunton J, Liu JO, Mitsiades CS, Hann BC, Aftab BT, Wiita AP. Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment. Haematologica. PMID 29622655 DOI: 10.3324/haematol.2017.174482  0.68
2016 Yang Z, Robinson MJ, Chen X, Smith GA, Taunton J, Liu W, Allen CD. Regulation of B cell fate by chronic activity of the IgE B cell receptor. Elife. 5. PMID 27935477 DOI: 10.7554/eLife.21238  0.68
2016 Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V, Hegde RS. Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell. 167: 1229-1240.e15. PMID 27863242 DOI: 10.1016/j.cell.2016.10.046  0.72
2016 Baron L, Paatero AO, Morel JD, Impens F, Guenin-Macé L, Saint-Auret S, Blanchard N, Dillmann R, Niang F, Pellegrini S, Taunton J, Paavilainen VO, Demangel C. Mycolactone subverts immunity by selectively blocking the Sec61 translocon. The Journal of Experimental Medicine. PMID 27821549 DOI: 10.1084/jem.20160662  0.8
2016 Josefowicz SZ, Shimada M, Armache A, Li CH, Miller RM, Lin S, Yang A, Dill BD, Molina H, Park HS, Garcia BA, Taunton J, Roeder RG, Allis CD. Chromatin Kinases Act on Transcription Factors and Histone Tails in Regulation of Inducible Transcription. Molecular Cell. 64: 347-361. PMID 27768872 DOI: 10.1016/j.molcel.2016.09.026  1
2016 Rodríguez-Molina JB, Tseng SC, Simonett SP, Taunton J, Ansari AZ. Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization. Molecular Cell. PMID 27477907 DOI: 10.1016/j.molcel.2016.06.036  0.32
2016 Paatero AO, Kellosalo J, Dunyak BM, Almaliti J, Gestwicki JE, Gerwick WH, Taunton J, Paavilainen VO. Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel. Cell Chemical Biology. 23: 561-6. PMID 27203376 DOI: 10.1016/j.chembiol.2016.04.008  0.8
2016 Smith GA, Uchida K, Weiss A, Taunton J. Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling. Nature Chemical Biology. PMID 27018889 DOI: 10.1038/nchembio.2056  0.68
2015 Carelli JD, Sethofer SG, Smith GA, Miller HR, Simard JL, Merrick WC, Jain RK, Ross NT, Taunton J. Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex. Elife. 4. PMID 26651998 DOI: 10.7554/eLife.10222  1
2015 Arrowsmith CH, Audia JE, Austin C, Baell J, Bennett J, Blagg J, Bountra C, Brennan PE, Brown PJ, Bunnage ME, Buser-Doepner C, Campbell RM, Carter AJ, Cohen P, Copeland RA, ... ... Taunton J, et al. Corrigendum: The promise and peril of chemical probes. Nature Chemical Biology. 11: 887. PMID 26485080 DOI: 10.1038/nchembio1115-887c  0.64
2015 Arrowsmith CH, Audia JE, Austin C, Baell J, Bennett J, Blagg J, Bountra C, Brennan PE, Brown PJ, Bunnage ME, Buser-Doepner C, Campbell RM, Carter AJ, Cohen P, Copeland RA, ... ... Taunton J, et al. The promise and peril of chemical probes. Nature Chemical Biology. 11: 536-41. PMID 26196764 DOI: 10.1038/nchembio.1867  1
2015 Bradshaw JM, McFarland JM, Paavilainen VO, Bisconte A, Tam D, Phan VT, Romanov S, Finkle D, Shu J, Patel V, Ton T, Li X, Loughhead DG, Nunn PA, Karr DE, ... ... Taunton J, et al. Prolonged and tunable residence time using reversible covalent kinase inhibitors. Nature Chemical Biology. 11: 525-31. PMID 26006010 DOI: 10.1038/nchembio.1817  1
2015 London N, Miller RM, Krishnan S, Uchida K, Irwin JJ, Eidam O, Gibold L, Cimerman?i? P, Bonnet R, Shoichet BK, Taunton J. Erratum: Covalent docking of large libraries for the discovery of chemical probes. Nature Chemical Biology. 11: 235. PMID 25689339 DOI: 10.1038/nchembio0315-235b  1
2015 Heo KS, Le NT, Cushman HJ, Giancursio CJ, Chang E, Woo CH, Sullivan MA, Taunton J, Yeh ET, Fujiwara K, Abe J. Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function. The Journal of Clinical Investigation. 125: 1299-310. PMID 25689261 DOI: 10.1172/JCI76453  1
2015 Ruiz-Saenz A, Sandhu M, Carrasco Y, Maglathlin RL, Taunton J, Moasser MM. Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum. Oncogene. PMID 25619841 DOI: 10.1038/onc.2014.455  0.44
2015 Ruiz-Saenz A, Sandhu M, Carrasco Y, Maglathlin RL, Taunton J, Moasser MM. Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum Oncogene. DOI: 10.1038/onc.2014.455  0.44
2014 Miller RM, Taunton J. Targeting protein kinases with selective and semipromiscuous covalent inhibitors. Methods in Enzymology. 548: 93-116. PMID 25399643 DOI: 10.1016/B978-0-12-397918-6.00004-5  1
2014 London N, Miller RM, Krishnan S, Uchida K, Irwin JJ, Eidam O, Gibold L, Cimermančič P, Bonnet R, Shoichet BK, Taunton J. Covalent docking of large libraries for the discovery of chemical probes. Nature Chemical Biology. 10: 1066-72. PMID 25344815 DOI: 10.1038/nchembio.1666  1
2014 Krishnan S, Miller RM, Tian B, Mullins RD, Jacobson MP, Taunton J. Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis. Journal of the American Chemical Society. 136: 12624-30. PMID 25153195 DOI: 10.1021/ja505194w  1
2014 Mackinnon AL, Paavilainen VO, Sharma A, Hegde RS, Taunton J. An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate. Elife. 3: e01483. PMID 24497544 DOI: 10.7554/eLife.01483  0.88
2014 MacKinnon AL, Paavilainen VO, Sharma A, Hegde RS, Taunton J. An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gate Elife. 2014. DOI: 10.7554/eLife.01483  1
2013 Li D, Jin L, Alesi GN, Kim YM, Fan J, Seo JH, Wang D, Tucker M, Gu TL, Lee BH, Taunton J, Magliocca KR, Chen ZG, Shin DM, Khuri FR, et al. The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis. The Journal of Biological Chemistry. 288: 32528-38. PMID 24085294 DOI: 10.1074/jbc.M113.500561  1
2013 Nishino M, Choy JW, Gushwa NN, Oses-Prieto JA, Koupparis K, Burlingame AL, Renslo AR, McKerrow JH, Taunton J. Hypothemicin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei Elife. 2013. PMID 23853713 DOI: 10.7554/eLife.00712  1
2013 Jin L, Li D, Lee JS, Elf S, Alesi GN, Fan J, Kang HB, Wang D, Fu H, Taunton J, Boggon TJ, Tucker M, Gu TL, Chen ZG, Shin DM, et al. p90 RSK2 Mediates Antianoikis Signals by both Transcription-Dependent and-Independent Mechanisms Molecular and Cellular Biology. 33: 2574-2585. PMID 23608533 DOI: 10.1128/MCB.01677-12  1
2013 Miller RM, Paavilainen VO, Krishnan S, Serafimova IM, Taunton J. Electrophilic fragment-based design of reversible covalent kinase inhibitors. Journal of the American Chemical Society. 135: 5298-301. PMID 23540679 DOI: 10.1021/ja401221b  1
2013 Paavilainen VO, Taunton J. Proteostasis modulators with discriminating taste. Chemistry & Biology. 20: 144-5. PMID 23438743 DOI: 10.1016/j.chembiol.2013.02.002  0.8
2013 Choy JW, Bryant C, Calvet CM, Doyle PS, Gunatilleke SS, Leung SS, Ang KK, Chen S, Gut J, Oses-Prieto JA, Johnston JB, Arkin MR, Burlingame AL, Taunton J, Jacobson MP, et al. Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target. Beilstein Journal of Organic Chemistry. 9: 15-25. PMID 23400640 DOI: 10.3762/bjoc.9.3  1
2013 Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, ... Taunton J, et al. A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis. Circulation. 127: 486-99. PMID 23243209 DOI: 10.1161/CIRCULATIONAHA.112.116988  1
2013 Paavilainen VO, Taunton J. Proteostasis modulators with discriminating taste Chemistry and Biology. 20: 144-145. DOI: 10.1016/j.chembiol.2013.02.002  1
2012 Gushwa NN, Kang S, Chen J, Taunton J. Selective targeting of distinct active site nucleophiles by irreversible Src-family kinase inhibitors Journal of the American Chemical Society. 134: 20214-20217. PMID 23190395 DOI: 10.1021/ja310659j  1
2012 Lakkaraju AK, Thankappan R, Mary C, Garrison JL, Taunton J, Strub K. Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation. Molecular Biology of the Cell. 23: 2712-22. PMID 22648169 DOI: 10.1091/mbc.E12-03-0228  1
2012 Serafimova IM, Pufall MA, Krishnan S, Duda K, Cohen MS, Maglathlin RL, McFarland JM, Miller RM, Frödin M, Taunton J. Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles. Nature Chemical Biology. 8: 471-6. PMID 22466421 DOI: 10.1038/nchembio.925  1
2012 Kapp GT, Liu S, Stein A, Wong DT, Reményi A, Yeh BJ, Fraser JS, Taunton J, Lim WA, Kortemme T. Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair. Proceedings of the National Academy of Sciences of the United States of America. 109: 5277-82. PMID 22403064 DOI: 10.1073/pnas.1114487109  1
2012 Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, et al. p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction. Circulation Research. 110: 536-50. PMID 22267842 DOI: 10.1161/CIRCRESAHA.111.254730  1
2011 Maifeld SV, MacKinnon AL, Garrison JL, Sharma A, Kunkel EJ, Hegde RS, Taunton J. Secretory protein profiling reveals TNF-α inactivation by selective and promiscuous Sec61 modulators. Chemistry & Biology. 18: 1082-8. PMID 21944747 DOI: 10.1016/j.chembiol.2011.06.015  1
2011 Cohen JD, Babiarz JE, Abrams RM, Guo L, Kameoka S, Chiao E, Taunton J, Kolaja KL. Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations. Toxicology and Applied Pharmacology. 257: 74-83. PMID 21906609 DOI: 10.1016/j.taap.2011.08.020  1
2011 Chen F, Pruett-Miller SM, Huang Y, Gjoka M, Duda K, Taunton J, Collingwood TN, Frodin M, Davis GD. High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases. Nature Methods. 8: 753-5. PMID 21765410 DOI: 10.1038/nmeth.1653  1
2011 Henise JC, Taunton J. Irreversible Nek2 kinase inhibitors with cellular activity Journal of Medicinal Chemistry. 54: 4133-4146. PMID 21627121 DOI: 10.1021/jm200222m  1
2011 Elf S, Blevins D, Jin L, Chung TW, Williams IR, Lee BH, Lin JX, Leonard WJ, Taunton J, Khoury HJ, Kang S. p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia Blood. 117: 6885-6894. PMID 21527514 DOI: 10.1182/blood-2010-10-315721  1
2010 Puthenveedu MA, Lauffer B, Temkin P, Vistein R, Carlton P, Thorn K, Taunton J, Weiner OD, Parton RG, von Zastrow M. Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell. 143: 761-73. PMID 21111236 DOI: 10.1016/j.cell.2010.10.003  1
2010 Oh YT, Liu X, Yue P, Kang S, Chen J, Taunton J, Khuri FR, Sun SY. ERK/ribosomal S6 kinase (RSK) signaling positively regulates death receptor 5 expression through co-activation of CHOP and Elk1. The Journal of Biological Chemistry. 285: 41310-9. PMID 21044953 DOI: 10.1074/jbc.M110.153775  1
2010 Kintner DB, Chen X, Currie J, Chanana V, Ferrazzano P, Baba A, Matsuda T, Cohen M, Orlowski J, Chiu SY, Taunton J, Sun D. Excessive Na+/H+ exchange in disruption of dendritic Na+ and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia. The Journal of Biological Chemistry. 285: 35155-68. PMID 20817726 DOI: 10.1074/jbc.M110.101212  1
2010 Manhas N, Shi Y, Taunton J, Sun D. P90RSK activation contributes to cerebral ischemic damage via phosphorylation of Na+/H+ exchanger isoform 1 Journal of Neurochemistry. 114: 1476-1486. PMID 20557427 DOI: 10.1111/j.1471-4159.2010.06868.x  1
2010 Lee S, Shuman JD, Guszczynski T, Sakchaisri K, Sebastian T, Copeland TD, Miller M, Cohen MS, Taunton J, Smart RC, Xiao Z, Yu LR, Veenstra TD, Johnson PF. RSK-mediated phosphorylation in the C/EBP{beta} leucine zipper regulates DNA binding, dimerization, and growth arrest activity. Molecular and Cellular Biology. 30: 2621-35. PMID 20351173 DOI: 10.1128/MCB.00782-09  1
2010 Kang S, Elf S, Lythgoe K, Hitosugi T, Taunton J, Zhou W, Xiong L, Wang D, Muller S, Fan S, Sun SY, Marcus AI, Gu TL, Polakiewicz RD, Chen ZG, et al. p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells. The Journal of Clinical Investigation. 120: 1165-77. PMID 20234090 DOI: 10.1172/JCI40582  1
2009 Mackinnon AL, Taunton J. Target Identification by Diazirine Photo-Cross-linking and Click Chemistry. Current Protocols in Chemical Biology. 1: 55-73. PMID 23667793 DOI: 10.1002/9780470559277.ch090167  0.88
2009 Doehn U, Hauge C, Frank SR, Jensen CJ, Duda K, Nielsen JV, Cohen MS, Johansen JV, Winther BR, Lund LR, Winther O, Taunton J, Hansen SH, Frödin M. RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Molecular Cell. 35: 511-22. PMID 19716794 DOI: 10.1016/j.molcel.2009.08.002  1
2009 Chaturvedi D, Cohen MS, Taunton J, Patel TB. The PKARIalpha subunit of protein kinase A modulates the activation of p90RSK1 and its function. The Journal of Biological Chemistry. 284: 23670-81. PMID 19570980 DOI: 10.1074/jbc.M109.032813  1
2009 Kang S, Elf S, Dong S, Hitosugi T, Lythgoe K, Guo A, Ruan H, Lonial S, Khoury HJ, Williams IR, Lee BH, Roesel JL, Karsenty G, Hanauer A, Taunton J, et al. Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation. Molecular and Cellular Biology. 29: 2105-17. PMID 19223461 DOI: 10.1128/MCB.00998-08  1
2009 Chaturvedi D, Gao X, Cohen MS, Taunton J, Patel TB. Rapamycin induces transactivation of the EGFR and increases cell survival. Oncogene. 28: 1187-96. PMID 19151764 DOI: 10.1038/onc.2008.490  1
2009 Dehan E, Bassermann F, Guardavaccaro D, Vasiliver-Shamis G, Cohen M, Lowes KN, Dustin M, Huang DC, Taunton J, Pagano M. betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis. Molecular Cell. 33: 109-16. PMID 19150432 DOI: 10.1016/j.molcel.2008.12.020  1
2008 Bowers A, West N, Taunton J, Schreiber SL, Bradner JE, Williams RM. Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor. Journal of the American Chemical Society. 130: 11219-22. PMID 18642817 DOI: 10.1021/ja8033763  1
2008 Lu Z, Abe J, Taunton J, Lu Y, Shishido T, McClain C, Yan C, Xu SP, Spangenberg TM, Xu H. Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity. Circulation Research. 103: 269-78. PMID 18599872 DOI: 10.1161/CIRCRESAHA.107.166678  1
2008 Visintin C, Tomson BN, Rahal R, Paulson J, Cohen M, Taunton J, Amon A, Visintin R. APC/C-Cdh1-mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus. Genes & Development. 22: 79-90. PMID 18172166 DOI: 10.1101/gad.1601308  1
2008 Visintin C, Tomson BN, Rahal R, Paulson J, Cohen M, Taunton J, Amon A, Visintin R. APC/C-Cdh1-mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus (Genes and Development (2008) 22 (79-90)) Genes and Development. 22: 1560.  1
2007 Snead JL, Sullivan M, Lowery DM, Cohen MS, Zhang C, Randle DH, Taunton J, Yaffe MB, Morgan DO, Shokat KM. A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration. Chemistry & Biology. 14: 1261-72. PMID 18022565 DOI: 10.1016/j.chembiol.2007.09.011  0.4
2007 MacKinnon AL, Garrison JL, Hegde RS, Taunton J. Photo-leucine incorporation reveals the target of a cyclodepsipeptide inhibitor of cotranslational translocation. Journal of the American Chemical Society. 129: 14560-1. PMID 17983236 DOI: 10.1021/ja076250y  1
2007 Kang S, Dong S, Gu TL, Guo A, Cohen MS, Lonial S, Khoury HJ, Fabbro D, Gilliland DG, Bergsagel PL, Taunton J, Polakiewicz RD, Chen J. FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway. Cancer Cell. 12: 201-14. PMID 17785202 DOI: 10.1016/j.ccr.2007.08.003  1
2007 Rutkowski DT, Kang SW, Goodman AG, Garrison JL, Taunton J, Katze MG, Kaufman RJ, Hegde RS. The role of p58IPK in protecting the stressed endoplasmic reticulum. Molecular Biology of the Cell. 18: 3681-91. PMID 17567950 DOI: 10.1091/mbc.E07-03-0272  1
2007 Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, Sonenberg N, Blenis J. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. The Journal of Biological Chemistry. 282: 14056-64. PMID 17360704 DOI: 10.1074/jbc.M700906200  1
2007 Co C, Wong DT, Gierke S, Chang V, Taunton J. Mechanism of actin network attachment to moving membranes: barbed end capture by N-WASP WH2 domains. Cell. 128: 901-13. PMID 17350575 DOI: 10.1016/j.cell.2006.12.049  1
2007 Cohen MS, Hadjivassiliou H, Taunton J. A clickable inhibitor reveals context-dependent autoactivation of p90 RSK. Nature Chemical Biology. 3: 156-60. PMID 17259979 DOI: 10.1038/nchembio859  1
2007 Hetzer C, Bisgrove D, Cohen MS, Pedal A, Kaehlcke K, Speyerer A, Bartscherer K, Taunton J, Ott M. Recruitment and activation of RSK2 by HIV-1 Tat. Plos One. 2: e151. PMID 17225856 DOI: 10.1371/journal.pone.0000151  1
2007 Cuello F, Snabaitis AK, Cohen MS, Taunton J, Avkiran M. Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the novel and specific RSK inhibitor fmk on responses to alpha1-adrenergic stimulation. Molecular Pharmacology. 71: 799-806. PMID 17142297 DOI: 10.1124/mol.106.029900  1
2006 Kang SW, Rane NS, Kim SJ, Garrison JL, Taunton J, Hegde RS. Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway. Cell. 127: 999-1013. PMID 17129784 DOI: 10.1016/j.cell.2006.10.032  1
2006 Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding HP, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, Ron D. Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload. Cell. 126: 727-39. PMID 16923392 DOI: 10.1016/j.cell.2006.06.051  1
2006 Shahbazian D, Roux PP, Mieulet V, Cohen MS, Raught B, Taunton J, Hershey JW, Blenis J, Pende M, Sonenberg N. The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. The Embo Journal. 25: 2781-91. PMID 16763566 DOI: 10.1038/sj.emboj.7601166  1
2006 Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding H, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, Ron D. Cotranslocational Degradation Protects the Stressed Endoplasmic Reticulum from Protein Overload (DOI:10.1016/j.cell.2006.06.051) Cell. 127: 1284. DOI: 10.1016/j.cell.2006.11.027  1
2005 Garrison JL, Kunkel EJ, Hegde RS, Taunton J. A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum. Nature. 436: 285-9. PMID 16015336 DOI: 10.1038/nature03821  1
2005 Cohen MS, Zhang C, Shokat KM, Taunton J. Structural bioinformatics-based design of selective, irreversible kinase inhibitors. Science (New York, N.Y.). 308: 1318-21. PMID 15919995 DOI: 10.1126/science1108367  0.4
2005 Papayannopoulos V, Co C, Prehoda KE, Snapper S, Taunton J, Lim WA. A polybasic motif allows N-WASP to act as a sensor of PIP(2) density. Molecular Cell. 17: 181-91. PMID 15664188 DOI: 10.1016/j.molcel.2004.11.054  1
2005 Deng S, Taunton J. Organolithium-mediated diversification of peptide thiazoles. Organic Letters. 7: 299-301. PMID 15646982 DOI: 10.1021/ol047660j  1
2003 Sokac AM, Co C, Taunton J, Bement W. Cdc42-dependent actin polymerization during compensatory endocytosis in Xenopus eggs. Nature Cell Biology. 5: 727-32. PMID 12872130 DOI: 10.1038/ncb1025  1
2002 Deng S, Taunton J. Kinetic control of proline amide rotamers: total synthesis of trans,trans- and cis,cis-ceratospongamide. Journal of the American Chemical Society. 124: 916-7. PMID 11829594 DOI: 10.1021/ja017160a  1
2001 Taunton J. Actin filament nucleation by endosomes, lysosomes and secretory vesicles. Current Opinion in Cell Biology. 13: 85-91. PMID 11163138 DOI: 10.1016/S0955-0674(00)00178-2  1
2000 Taunton J, Rowning BA, Coughlin ML, Wu M, Moon RT, Mitchison TJ, Larabell CA. Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP. The Journal of Cell Biology. 148: 519-30. PMID 10662777 DOI: 10.1083/jcb.148.3.519  1
1997 Taunton J. How to starve a tumor Chemistry and Biology. 4: 493-496. PMID 9263636  1
1996 Taunton J, Hassig CA, Schreiber SL. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science (New York, N.Y.). 272: 408-11. PMID 8602529  1
1996 Taunton J, Collins JL, Schreiber SL. Synthesis of natural and modified trapoxins, useful reagents for exploring histone deacetylase function Journal of the American Chemical Society. 118: 10412-10422. DOI: 10.1021/ja9615841  1
Show low-probability matches.