| Year |
Citation |
Score |
| Low-probability matches (unlikely to be authored by this person) |
| 2019 |
Cioffi CL, Racz B, Váradi A, Freeman E, Conlon MP, Chen P, Zhu L, Kitchen DB, Barnes K, Martin W, Pearson P, Johnson G, Blaner WS, Petrukhin K. Design, Synthesis, and Pre-Clinical Efficacy of Novel Non-Retinoid Antagonists of Retinol Binding Protein 4 in the Mouse Model of Hepatic Steatosis. Journal of Medicinal Chemistry. PMID 31079449 DOI: 10.1021/Acs.Jmedchem.9B00352 |
0.01 |
|
| 2019 |
Frohlich KM, Weintraub S, Bell JT, Todd GC, Väre VY, Schneider R, Kloos ZA, Tabe ES, Cantara WA, Stark C, Onwuanaibe U, Duffy BC, Basanta-Sanchez M, Kitchen DB, McDonough K, et al. Discovery of small molecule antibiotics against a unique tRNA-mediated regulation of transcription in Gram-positive bacteria. Chemmedchem. PMID 30707489 DOI: 10.1002/Cmdc.201800744 |
0.01 |
|
| 2018 |
Kharenko O, Patel RG, Brown SD, Calosing C, White A, Lakshminarasimhan D, Suto RK, Duffy BC, Kitchen DB, McLure KG, Hansen HC, van der Horst EH, Young PR. DESIGN AND CHARACTERIZATION OF NOVEL COVALENT BROMODOMAIN AND EXTRA-TERMINAL DOMAIN (BET) INHIBITORS TARGETING A METHIONINE. Journal of Medicinal Chemistry. PMID 30165024 DOI: 10.1021/Acs.Jmedchem.8B00666 |
0.01 |
|
| 2016 |
Kitchen DB. Computer-aided drug discovery research at a global contract research organization. Journal of Computer-Aided Molecular Design. PMID 27804014 DOI: 10.1007/s10822-016-9991-3 |
0.01 |
|
| 2015 |
Aziz RK, Monk JM, Lewis RM, In Loh S, Mishra A, Abhay Nagle A, Satyanarayana C, Dhakshinamoorthy S, Luche M, Kitchen DB, Andrews KA, Fong NL, Li HJ, Palsson BO, Charusanti P. Systems biology-guided identification of synthetic lethal gene pairs and its potential use to discover antibiotic combinations. Scientific Reports. 5: 16025. PMID 26531810 DOI: 10.1038/Srep16025 |
0.01 |
|
| 2015 |
Aziz RK, Khaw VL, Monk JM, Brunk E, Lewis R, Loh SI, Mishra A, Nagle AA, Satyanarayana C, Dhakshinamoorthy S, Luche M, Kitchen DB, Andrews KA, Palsson BØ, Charusanti P. Model-driven discovery of synergistic inhibitors against E. coli and S. enterica serovar Typhimurium targeting a novel synthetic lethal pair, aldA and prpC. Frontiers in Microbiology. 6: 958. PMID 26441892 DOI: 10.3389/Fmicb.2015.00958 |
0.01 |
|
| 2015 |
Cioffi CL, Racz B, Freeman EE, Conlon MP, Chen P, Stafford DG, Schwarz DM, Zhu L, Kitchen DB, Barnes KD, Dobri N, Michelotti E, Cywin CL, Martin WH, Pearson PG, et al. Bicyclic [3.3.0]-Octahydrocyclopenta[c]pyrrolo Antagonists of Retinol Binding Protein 4: Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease. Journal of Medicinal Chemistry. PMID 26181715 DOI: 10.1021/Acs.Jmedchem.5B00423 |
0.01 |
|
| 2015 |
Duffy BC, Liu S, Martin GS, Wang R, Hsia MM, Zhao H, Guo C, Ellis M, Quinn JF, Kharenko OA, Norek K, Gesner EM, Young PR, McLure KG, Wagner GS, ... ... Kitchen DB, et al. Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design. Bioorganic & Medicinal Chemistry Letters. 25: 2818-23. PMID 26022843 DOI: 10.1016/J.Bmcl.2015.04.107 |
0.01 |
|
| 2015 |
Wityak J, McGee KF, Conlon MP, Song RH, Duffy BC, Clayton B, Lynch M, Wang G, Freeman E, Haber J, Kitchen DB, Manning DD, Ismail J, Khmelnitsky Y, Michels P, et al. Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors. Journal of Medicinal Chemistry. 58: 2967-87. PMID 25760409 DOI: 10.1021/jm5013598 |
0.01 |
|
| 2014 |
Cioffi CL, Dobri N, Freeman EE, Conlon MP, Chen P, Stafford DG, Schwarz DM, Golden KC, Zhu L, Kitchen DB, Barnes KD, Racz B, Qin Q, Michelotti E, Cywin CL, et al. Design, synthesis, and evaluation of nonretinoid retinol binding protein 4 antagonists for the potential treatment of atrophic age-related macular degeneration and Stargardt disease. Journal of Medicinal Chemistry. 57: 7731-57. PMID 25210858 DOI: 10.1021/Jm5010013 |
0.01 |
|
| 2014 |
Guo C, Hu M, DeOrazio RJ, Usyatinsky A, Fitzpatrick K, Zhang Z, Maeng JH, Kitchen DB, Tom S, Luche M, Khmelnitsky Y, Mhyre AJ, Guzzo PR, Liu S. The design and synthesis of novel SGLT2 inhibitors: C-glycosides with benzyltriazolopyridinone and phenylhydantoin as the aglycone moieties. Bioorganic & Medicinal Chemistry. 22: 3414-22. PMID 24842618 DOI: 10.1016/j.bmc.2014.04.036 |
0.01 |
|
| 2012 |
Pechulis AD, Beck JP, Curry MA, Wolf MA, Harms AE, Xi N, Opalka C, Sweet MP, Yang Z, Vellekoop AS, Klos AM, Crocker PJ, Hassler C, Laws M, Kitchen DB, et al. 4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 7219-22. PMID 23084899 DOI: 10.1016/j.bmcl.2012.09.050 |
0.01 |
|
| 2012 |
Duffy BC, Zhu L, Decornez H, Kitchen DB. Early phase drug discovery: cheminformatics and computational techniques in identifying lead series. Bioorganic & Medicinal Chemistry. 20: 5324-42. PMID 22938785 DOI: 10.1016/j.bmc.2012.04.062 |
0.01 |
|
| 2011 |
Pabba C, Gregg BT, Kitchen DB, Chen ZJ, Judkins A. Design and synthesis of aryl ether and sulfone hydroxamic acids as potent histone deacetylase (HDAC) inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 324-8. PMID 21109435 DOI: 10.1016/j.bmcl.2010.11.006 |
0.01 |
|
| 2010 |
Bai M, Carr G, Deorazio RJ, Friedrich TD, Dobritsa S, Fitzpatrick K, Guzzo PR, Kitchen DB, Lynch MA, Peace D, Sajad M, Usyatinsky A, Wolf MA. 5-Functionalized indazoles as glucocorticoid receptor agonists. Bioorganic & Medicinal Chemistry Letters. 20: 3017-20. PMID 20427184 DOI: 10.1016/J.Bmcl.2010.04.012 |
0.01 |
|
| 2009 |
Decornez H, Gulyás-Forró A, Papp A, Szabó M, Sármay G, Hajdú I, Cseh S, Dormán G, Kitchen DB. Design, selection, and evaluation of a general kinase-focused library. Chemmedchem. 4: 1273-8. PMID 19551802 DOI: 10.1002/cmdc.200900164 |
0.01 |
|
| 2006 |
Subramanian G, Kitchen DB. Computational approaches for modeling human intestinal absorption and permeability. Journal of Molecular Modeling. 12: 577-89. PMID 16583199 DOI: 10.1007/s00894-005-0065-z |
0.01 |
|
| 2004 |
Kitchen DB, Decornez H, Furr JR, Bajorath J. Docking and scoring in virtual screening for drug discovery: methods and applications. Nature Reviews. Drug Discovery. 3: 935-49. PMID 15520816 DOI: 10.1038/nrd1549 |
0.01 |
|
| 2003 |
Subramanian G, Kitchen DB. Computational models to predict blood-brain barrier permeation and CNS activity. Journal of Computer-Aided Molecular Design. 17: 643-64. PMID 15068364 |
0.01 |
|
| 2002 |
Godden JW, Xue L, Kitchen DB, Stahura FL, Schermerhorn EJ, Bajorath J. Median Partitioning: a novel method for the selection of representative subsets from large compound pools. Journal of Chemical Information and Computer Sciences. 42: 885-93. PMID 12132890 DOI: 10.1021/ci0203693 |
0.01 |
|
| Hide low-probability matches. |