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Paul A Dalby - Publications

Affiliations: 
University College London, London, United Kingdom 
Area:
Protein engineering and formulation
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Zhang C, Samad M, Yu H, Chakroun N, Hilton D, Dalby PA. Computational-design to reduce conformational flexibility and aggregation rates of an antibody Fab fragment. Molecular Pharmaceutics. PMID 29897777 DOI: 10.1021/acs.molpharmaceut.8b00186  0.307
2017 Robinson MJ, Matejtschuk P, Bristow AF, Dalby PA. Tm-values and unfolded fraction can predict aggregation rates for GCSF variant formulations, but not under predominantly native conditions. Molecular Pharmaceutics. PMID 29141152 DOI: 10.1021/acs.molpharmaceut.7b00876  0.326
2016 Morris P, Rios-Solis L, García-Arrazola R, Lye GJ, Dalby PA. Impact of cofactor-binding loop mutations on thermotolerance and activity of E. coli transketolase. Enzyme and Microbial Technology. 89: 85-91. PMID 27233131 DOI: 10.1016/j.enzmictec.2016.04.003  0.308
2008 Aucamp JP, Martinez-Torres RJ, Hibbert EG, Dalby PA. A microplate-based evaluation of complex denaturation pathways: structural stability of Escherichia coli transketolase. Biotechnology and Bioengineering. 99: 1303-10. PMID 17969139 DOI: 10.1002/bit.21705  0.313
2001 Dalby PA, Hoess RH, DeGrado WF. Evolution of binding affinity in a WW domain probed by phage display. Protein Science : a Publication of the Protein Society. 9: 2366-76. PMID 11206058 DOI: 10.1110/Ps.9.12.2366  0.325
1998 Dalby PA, Clarke J, Johnson CM, Fersht AR. Folding intermediates of wild-type and mutants of barnase. II. Correlation of changes in equilibrium amide exchange kinetics with the population of the folding intermediate. Journal of Molecular Biology. 276: 647-56. PMID 9551102 DOI: 10.1006/Jmbi.1997.1547  0.427
1998 Dalby PA, Oliveberg M, Fersht AR. Folding intermediates of wild-type and mutants of barnase. I. use of @f-value analysis and m-values to probe the cooperative nature of the folding pre-equilibrium Journal of Molecular Biology. 276: 625-646. PMID 9551101 DOI: 10.1006/Jmbi.1997.1546  0.454
1998 Dalby PA, Oliveberg M, Fersht AR. Movement of the Intermediate and Rate Determining Transition State of Barnase on the Energy Landscape with Changing Temperature Biochemistry. 37: 4674-4679. PMID 9521788 DOI: 10.1021/Bi972798D  0.414
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