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Michael B. Miller - Publications

Affiliations: 
Brigham and Women's Hospital / Harvard Medical School 
Area:
prion disease, protein misfolding, genomics, neuropathology, neurodegeneration, Alzheimer's disease
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Zhou Z, Luquette LJ, Dong G, Kim J, Ku J, Kim K, Bae M, Shao DD, Sahile B, Miller MB, Huang AY, Nathan WJ, Nussenzweig A, Park PJ, Lagier-Tourenne C, et al. Recurrent patterns of widespread neuronal genomic damage shared by major neurodegenerative disorders. Biorxiv : the Preprint Server For Biology. PMID 40093130 DOI: 10.1101/2025.03.03.641186  0.762
2025 Dong G, Ma CC, Mao S, Naik SM, Brown KS, McDonough GA, Kim J, Kirkham SL, Cherry JD, Uretsky M, Spurlock E, McKee AC, Huang AY, Miller MB, Lee EA, et al. Diverse somatic genomic alterations in single neurons in chronic traumatic encephalopathy. Biorxiv : the Preprint Server For Biology. PMID 40093089 DOI: 10.1101/2025.03.03.641217  0.76
2024 Nandu N, Miller M, Tong Y, Lu ZX. A novel dual probe-based method for mutation detection using isothermal amplification. Plos One. 19: e0309541. PMID 39436873 DOI: 10.1371/journal.pone.0309541  0.323
2024 McDonough GA, Cheng Y, Morillo KS, Doan RN, Zhou Z, Kenny CJ, Foutz A, Kim C, Cohen ML, Appleby BS, Walsh CA, Safar JG, Huang AY, Miller MB. Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease. Acta Neuropathologica. 148: 10. PMID 39048735 DOI: 10.1007/s00401-024-02774-2  0.815
2024 McDonough GA, Cheng Y, Morillo K, Doan RN, Kenny CJ, Foutz A, Kim C, Cohen ML, Appleby BS, Walsh CA, Safar JG, Huang AY, Miller MB. Neuropathologically-directed profiling of somatic and germline variants in sporadic human prion disease. Biorxiv : the Preprint Server For Biology. PMID 38979287 DOI: 10.1101/2024.06.25.600668  0.791
2024 Ganz J, Luquette LJ, Bizzotto S, Miller MB, Zhou Z, Bohrson CL, Jin H, Tran AV, Viswanadham VV, McDonough G, Brown K, Chahine Y, Chhouk B, Galor A, Park PJ, et al. Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes. Cell. PMID 38503282 DOI: 10.1016/j.cell.2024.02.025  0.81
2024 Huang AY, Zhou Z, Talukdar M, Miller MB, Chhouk B, Enyenihi L, Rosen I, Stronge E, Zhao B, Kim D, Choi J, Khoshkhoo S, Kim J, Ganz J, Travaglini K, et al. Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer's disease microglia. Biorxiv : the Preprint Server For Biology. PMID 38260600 DOI: 10.1101/2024.01.03.574078  0.814
2023 Zhou Z, Kim J, Huang AY, Nolan M, Park J, Doan R, Shin T, Miller MB, Chhouk B, Morillo K, Yeh RC, Kenny C, Neil JE, Lee CZ, Ohkubo T, et al. Somatic Mosaicism in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Reveals Widespread Degeneration from Focal Mutations. Biorxiv : the Preprint Server For Biology. PMID 38077003 DOI: 10.1101/2023.11.30.569436  0.821
2023 Ganz J, Luquette LJ, Bizzotto S, Bohrson CL, Jin H, Miller MB, Zhou Z, Galor A, Park PJ, Walsh CA. Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain. Biorxiv : the Preprint Server For Biology. PMID 36711756 DOI: 10.1101/2023.01.14.523958  0.812
2022 Kim J, Huang AY, Johnson SL, Lai J, Isacco L, Jeffries AM, Miller MB, Lodato MA, Walsh CA, Lee EA. Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders. Nature Communications. 13: 5918. PMID 36207339 DOI: 10.1038/s41467-022-33642-w  0.807
2022 Luquette LJ, Miller MB, Zhou Z, Bohrson CL, Zhao Y, Jin H, Gulhan D, Ganz J, Bizzotto S, Kirkham S, Hochepied T, Libert C, Galor A, Kim J, Lodato MA, et al. Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements. Nature Genetics. PMID 36163278 DOI: 10.1038/s41588-022-01180-2  0.802
2022 Choudhury S, Huang AY, Kim J, Zhou Z, Morillo K, Maury EA, Tsai JW, Miller MB, Lodato MA, Araten S, Hilal N, Lee EA, Chen MH, Walsh CA. Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity. Nature Aging. 2: 714-725. PMID 36051457 DOI: 10.1038/s43587-022-00261-5  0.78
2022 Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, ... ... Miller M, et al. Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Science (New York, N.Y.). 377: 511-517. PMID 35901164 DOI: 10.1126/science.abm6222  0.735
2022 Miller MB, Huang AY, Kim J, Zhou Z, Kirkham SL, Maury EA, Ziegenfuss JS, Reed HC, Neil JE, Rento L, Ryu SC, Ma CC, Luquette LJ, Ames HM, Oakley DH, et al. Somatic genomic changes in single Alzheimer's disease neurons. Nature. PMID 35444284 DOI: 10.1038/s41586-022-04640-1  0.707
2021 Miller MB, Reed HC, Walsh CA. Brain Somatic Mutation in Aging and Alzheimer's Disease. Annual Review of Genomics and Human Genetics. PMID 33979534 DOI: 10.1146/annurev-genom-121520-081242  0.793
2021 Doan RN, Miller MB, Kim SN, Rodin RE, Ganz J, Bizzotto S, Morillo KS, Huang AY, Digumarthy R, Zemmel Z, Walsh CA. MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations. Bmc Medical Genomics. 14: 47. PMID 33579278 DOI: 10.1186/s12920-021-00893-3  0.789
2020 Kim J, Zhao B, Huang AY, Miller MB, Lodato MA, Walsh CA, Lee EA. APP gene copy number changes reflect exogenous contamination. Nature. 584: E20-E28. PMID 32814883 DOI: 10.1038/S41586-020-2522-3  0.733
2016 Miller MB, Bi WL, Ramkissoon LA, Kang YJ, Abedalthagafi M, Knoff DS, Agarwalla PK, Wen PY, Reardon DA, Alexander BM, Laws ER, Dunn IF, Beroukhim R, Ligon KL, Ramkissoon SH. MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma. Oncotarget. PMID 27175596 DOI: 10.18632/Oncotarget.9244  0.301
2015 Noble GP, Wang DW, Walsh DJ, Barone JR, Miller MB, Nishina KA, Li S, Supattapone S. A Structural and Functional Comparison Between Infectious and Non-Infectious Autocatalytic Recombinant PrP Conformers. Plos Pathogens. 11: e1005017. PMID 26125623 DOI: 10.1371/Journal.Ppat.1005017  0.559
2015 Noble GP, Walsh DJ, Miller MB, Jackson WS, Supattapone S. Requirements for mutant and wild-type prion protein misfolding in vitro. Biochemistry. 54: 1180-7. PMID 25584902 DOI: 10.1021/bi501495j  0.616
2013 Miller MB, Wang DW, Wang F, Noble GP, Ma J, Woods VL, Li S, Supattapone S. Cofactor molecules induce structural transformation during infectious prion formation. Structure (London, England : 1993). 21: 2061-8. PMID 24120764 DOI: 10.1016/J.Str.2013.08.025  0.577
2013 Supattapone S, Miller MB. Cofactor involvement in prion propagation Prions and Diseases. 1: 93-105. DOI: 10.1007/978-1-4614-5305-5_7  0.543
2012 Turnbaugh JA, Unterberger U, Saá P, Massignan T, Fluharty BR, Bowman FP, Miller MB, Supattapone S, Biasini E, Harris DA. The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8817-30. PMID 22745483 DOI: 10.1523/Jneurosci.1103-12.2012  0.581
2011 Miller MB, Geoghegan JC, Supattapone S. Dissociation of infectivity from seeding ability in prions with alternate docking mechanism. Plos Pathogens. 7: e1002128. PMID 21779169 DOI: 10.1371/journal.ppat.1002128  0.755
2011 Miller MB, Supattapone S. Superparamagnetic nanoparticle capture of prions for amplification. Journal of Virology. 85: 2813-7. PMID 21228242 DOI: 10.1128/JVI.02451-10  0.551
2009 Fransen S, Gupta S, Danovich R, Hazuda D, Miller M, Witmer M, Petropoulos CJ, Huang W. Loss of raltegravir susceptibility by human immunodeficiency virus type 1 is conferred via multiple nonoverlapping genetic pathways. Journal of Virology. 83: 11440-6. PMID 19759152 DOI: 10.1128/JVI.01168-09  0.334
2009 Geoghegan JC, Miller MB, Kwak AH, Harris BT, Supattapone S. Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor. Plos Pathogens. 5: e1000535. PMID 19649330 DOI: 10.1371/Journal.Ppat.1000535  0.754
2009 Rhyne J, Mantaring MM, Gardner DF, Miller M. Multiple splice defects in ABCA1 cause low HDL-C in a family with hypoalphalipoproteinemia and premature coronary disease. Bmc Medical Genetics. 10: 1-11. PMID 19133158 DOI: 10.1186/1471-2350-10-1  0.358
2008 McCue ME, Valberg SJ, Miller MB, Wade C, DiMauro S, Akman HO, Mickelson JR. Glycogen synthase (GYS1) mutation causes a novel skeletal muscle glycogenosis. Genomics. 91: 458-66. PMID 18358695 DOI: 10.1016/J.Ygeno.2008.01.011  0.328
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