James C. Geoghegan - Publications

Affiliations: 
Biochemistry Dartmouth College, Hanover, NH, United States 

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Geoghegan JC, Gilmore BL, Davidson BL. Gene Silencing Mediated by siRNA-binding Fusion Proteins Is Attenuated by Double-stranded RNA-binding Domain Structure. Molecular Therapy. Nucleic Acids. 1: e53. PMID 23629028 DOI: 10.1038/Mtna.2012.43  0.334
2012 Deleault NR, Piro JR, Walsh DJ, Wang F, Ma J, Geoghegan JC, Supattapone S. Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 109: 8546-51. PMID 22586108 DOI: 10.1073/Pnas.1204498109  0.648
2011 Miller MB, Geoghegan JC, Supattapone S. Dissociation of infectivity from seeding ability in prions with alternate docking mechanism. Plos Pathogens. 7: e1002128. PMID 21779169 DOI: 10.1371/journal.ppat.1002128  0.698
2010 Deleault NR, Kascsak R, Geoghegan JC, Supattapone S. Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro. Biochemistry. 49: 3928-34. PMID 20377181 DOI: 10.1021/bi100370b  0.718
2009 Geoghegan JC, Miller MB, Kwak AH, Harris BT, Supattapone S. Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor. Plos Pathogens. 5: e1000535. PMID 19649330 DOI: 10.1371/Journal.Ppat.1000535  0.713
2007 Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, Harris BT, Supattapone S. Selective incorporation of polyanionic molecules into hamster prions. The Journal of Biological Chemistry. 282: 36341-53. PMID 17940287 DOI: 10.1074/Jbc.M704447200  0.668
2006 Gavin BA, Dolph MJ, Deleault NR, Geoghegan JC, Khurana V, Feany MB, Dolph PJ, Supattapone S. Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Sträussler-Scheinker syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12408-14. PMID 17135402 DOI: 10.1523/Jneurosci.3372-06.2006  0.63
2006 Supattapone S, Geoghegan JC, Rees JR. On the horizon: a blood test for prions. Trends in Microbiology. 14: 149-51. PMID 16483780 DOI: 10.1016/j.tim.2006.02.001  0.546
2006 Orem NR, Geoghegan JC, Deleault NR, Kascsak R, Supattapone S. Copper (II) ions potently inhibit purified PrPres amplification. Journal of Neurochemistry. 96: 1409-15. PMID 16417569 DOI: 10.1111/J.1471-4159.2006.03650.X  0.601
2005 Deleault NR, Geoghegan JC, Nishina K, Kascsak R, Williamson RA, Supattapone S. Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions. The Journal of Biological Chemistry. 280: 26873-9. PMID 15917229 DOI: 10.1074/Jbc.M503973200  0.667
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