Year |
Citation |
Score |
2023 |
Pagnamenta AT, Camps C, Giacopuzzi E, Taylor JM, Hashim M, Calpena E, Kaisaki PJ, Hashimoto A, Yu J, Sanders E, Schwessinger R, Hughes JR, Lunter G, Dreau H, Ferla M, ... ... Harris AL, et al. Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases. Genome Medicine. 15: 94. PMID 37946251 DOI: 10.1186/s13073-023-01240-0 |
0.567 |
|
2023 |
Wang Z, Zhang N, Zhang M, Jiang Y, Ng AS, Bridges E, Zhang W, Zeng X, Luo Q, Liang J, Gyorffy B, Hublitz P, Liang Z, Fischer R, Kerr D, ... Harris AL, et al. GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner. Cancer Research. PMID 37463466 DOI: 10.1158/0008-5472.CAN-22-3471 |
0.349 |
|
2023 |
Lord SR, Harris AL. Is it still worth pursuing the repurposing of metformin as a cancer therapeutic? British Journal of Cancer. PMID 36823364 DOI: 10.1038/s41416-023-02204-2 |
0.64 |
|
2023 |
Yu T, Jadhav AC, Xu J, Harris AL, Nair V, Huang WE. Metabolic Reprogramming in Colon Cancer Cells Persistently Infected with Newcastle Disease Virus. Cancers. 15. PMID 36765769 DOI: 10.3390/cancers15030811 |
0.493 |
|
2022 |
Harris BHL, Macaulay VM, Harris DA, Klenerman P, Karpe F, Lord SR, Harris AL, Buffa FM. Obesity: a perfect storm for carcinogenesis. Cancer Metastasis Reviews. PMID 36038791 DOI: 10.1007/s10555-022-10046-2 |
0.711 |
|
2022 |
Badve SS, Cho S, Lu X, Cao S, Ghose S, Thike AA, Tan PH, Ocal IT, Generali D, Zanconati F, Harris AL, Ginty F, Gökmen-Polar Y. Tumor Infiltrating Lymphocytes in Multi-National Cohorts of Ductal Carcinoma In Situ (DCIS) of Breast. Cancers. 14. PMID 36010908 DOI: 10.3390/cancers14163916 |
0.503 |
|
2022 |
Zois CE, Hendriks AM, Haider S, Pires E, Bridges E, Kalamida D, Voukantsis D, Lagerholm BC, Fehrmann RSN, den Dunnen WFA, Tarasov AI, Baba O, Morris J, Buffa FM, McCullagh JSO, ... ... Harris AL, et al. Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation. Cell Death & Disease. 13: 573. PMID 35764612 DOI: 10.1038/s41419-022-05005-2 |
0.504 |
|
2022 |
Arnaiz E, Harris AL. Role of Hypoxia in the Interferon Response. Frontiers in Immunology. 13: 821816. PMID 35251003 DOI: 10.3389/fimmu.2022.821816 |
0.325 |
|
2022 |
Carroll CP, Bolland H, Vancauwenberghe E, Collier P, Ritchie AA, Clarke PA, Grabowska AM, Harris AL, McIntyre A. Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis. Neoplasia (New York, N.Y.). 25: 41-52. PMID 35150959 DOI: 10.1016/j.neo.2022.01.003 |
0.351 |
|
2022 |
Schilling K, Harris AL, Halliday AN, Schofield CJ, Sheldon H, Haider S, Larner F. Investigations on Zinc Isotope Fractionation in Breast Cancer Tissue Using Cell Culture Uptake-Efflux Experiments. Frontiers in Medicine. 8: 746532. PMID 35127740 DOI: 10.3389/fmed.2021.746532 |
0.517 |
|
2021 |
Sheldon H, Alexander J, Bridges E, Moreira L, Reilly S, Ang KH, Wang D, Lin S, Haider S, Banham AH, Harris AL. ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype. International Journal of Molecular Sciences. 22. PMID 34681953 DOI: 10.3390/ijms222011293 |
0.811 |
|
2021 |
Sheldon H, Bridges E, Silva I, Masiero M, Favara DM, Wang D, Leek R, Snell C, Roxanis I, Kreuzer M, Gileadi U, Buffa FM, Banham A, Harris AL. ADGRL4/ELTD1 expression in breast cancer cells induces vascular normalisation and immune suppression. Molecular Cancer Research : McR. PMID 34348993 DOI: 10.1158/1541-7786.MCR-21-0171 |
0.825 |
|
2021 |
Giatromanolaki A, Harris AL, Koukourakis MI. The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer. Cancer & Metabolism. 9: 28. PMID 34344457 DOI: 10.1186/s40170-021-00264-7 |
0.541 |
|
2021 |
Goedegebuure RSA, Kleibeuker EA, Buffa FM, Castricum KCM, Haider S, Schulkens IA, Ten Kroode L, van den Berg J, Jacobs MAJM, van Berkel AM, van Grieken NCT, Derks S, Slotman BJ, Verheul HMW, Harris AL, et al. Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation. Journal of Experimental & Clinical Cancer Research : Cr. 40: 161. PMID 33964942 DOI: 10.1186/s13046-021-01962-2 |
0.772 |
|
2021 |
Artibani M, Masuda K, Hu Z, Rauher PC, Mallett G, Wietek N, Morotti M, Chong K, KaramiNejadRanjbar M, Zois CE, Dhar S, El-Sahhar S, Campo L, Blagden SP, Damato S, ... ... Harris AL, et al. Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor initiating cells. Jci Insight. PMID 33945502 DOI: 10.1172/jci.insight.147929 |
0.779 |
|
2021 |
Xu J, Yu T, Zois CE, Cheng JX, Tang Y, Harris AL, Huang WE. Unveiling Cancer Metabolism through Spontaneous and Coherent Raman Spectroscopy and Stable Isotope Probing. Cancers. 13. PMID 33916413 DOI: 10.3390/cancers13071718 |
0.446 |
|
2021 |
Favara DM, Liebscher I, Jazayeri A, Nambiar M, Sheldon H, Banham AH, Harris AL. Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling. Scientific Reports. 11: 8870. PMID 33893326 DOI: 10.1038/s41598-021-85408-x |
0.755 |
|
2021 |
Fanfani V, Citi L, Harris AL, Pezzella F, Stracquadanio G. The landscape of the heritable cancer genome. Cancer Research. PMID 33731442 DOI: 10.1158/0008-5472.CAN-20-3348 |
0.543 |
|
2021 |
Skwarski M, McGowan DR, Belcher E, Di Chiara F, Stavroulias D, McCole MG, Derham J, Chu KY, Teoh E, Chauhan J, O'Reilly D, Harris BHL, Macklin PS, Bull JA, Green M, ... ... Harris AL, et al. Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non-Small Cell Lung Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33597271 DOI: 10.1158/1078-0432.CCR-20-4128 |
0.593 |
|
2020 |
Baird RD, Linossi C, Middleton M, Lord S, Harris A, Rodón J, Zitt C, Fiedler U, Dawson KM, Leupin N, Stumpp MT, Harstrick A, Azaro A, Fischer S, Omlin A. First-in-Human Phase I Study of MP0250, a First-in-Class DARPin Drug Candidate Targeting VEGF and HGF, in Patients With Advanced Solid Tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2000596. PMID 33301375 DOI: 10.1200/JCO.20.00596 |
0.659 |
|
2020 |
Morotti M, Zois CE, El-Ansari R, Craze ML, Rakha EA, Fan SJ, Valli A, Haider S, Goberdhan DCI, Green AR, Harris AL. Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer. British Journal of Cancer. PMID 33028955 DOI: 10.1038/s41416-020-01113-y |
0.819 |
|
2020 |
de Heer EC, Jalving M, Harris AL. HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer. The Journal of Clinical Investigation. PMID 32870818 DOI: 10.1172/JCI137552 |
0.335 |
|
2020 |
Kawashima M, Bensaad K, Zois CE, Barberis A, Bridges E, Wigfield S, Lagerholm C, Dmitriev RI, Tokiwa M, Toi M, Papkovsky DB, Buffa FM, Harris AL. Correction to: Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells. Cancer & Metabolism. 8: 18. PMID 32789015 DOI: 10.1186/s40170-020-00224-7 |
0.767 |
|
2020 |
Walsh CA, Akrap N, Garre E, Magnusson Y, Harrison H, Andersson D, Jonasson E, Rafnsdottir S, Choudhry H, Buffa F, Ragoussis J, Ståhlberg A, Harris A, Landberg G. The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer. Plos One. 15: e0236187. PMID 32692762 DOI: 10.1371/journal.pone.0236187 |
0.622 |
|
2020 |
Kawashima M, Bensaad K, Zois CE, Barberis A, Bridges E, Wigfield S, Lagerholm C, Dmitriev RI, Tokiwa M, Toi M, Papkovsky DB, Buffa FM, Harris AL. Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells. Cancer & Metabolism. 8: 13. PMID 32647572 DOI: 10.1186/S40170-020-00219-4 |
0.778 |
|
2020 |
Dhawan A, Scott J, Sundaresan P, Veness M, Porceddu S, Hau E, Harris AL, Buffa FM, Gee HE. Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer. Scientific Reports. 10: 10226. PMID 32576885 DOI: 10.1038/S41598-020-66983-X |
0.684 |
|
2020 |
Fanfani V, Zatopkova M, Harris AL, Pezzella F, Stracquadanio G. Dissecting the heritable risk of breast cancer: from statistical methods to susceptibility genes. Seminars in Cancer Biology. PMID 32569822 DOI: 10.1016/j.semcancer.2020.06.001 |
0.557 |
|
2020 |
Bridges E, Sheldon H, Kleibeuker E, Ramberger E, Zois C, Barnard A, Harjes U, Li JL, Masiero M, MacLaren R, Harris A. RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain. Angiogenesis. PMID 32506201 DOI: 10.1007/S10456-020-09726-W |
0.795 |
|
2020 |
Giatromanolaki A, Harris AL, Banham AH, Contrafouris CA, Koukourakis MI. Carbonic anhydrase 9 (CA9) expression in non-small-cell lung cancer: correlation with regulatory FOXP3+T-cell tumour stroma infiltration. British Journal of Cancer. PMID 32066909 DOI: 10.1038/s41416-020-0756-3 |
0.454 |
|
2019 |
Lord SR, Collins JM, Cheng WC, Haider S, Wigfield S, Gaude E, Fielding BA, Pinnick KE, Harjes U, Segaran A, Jha P, Hoefler G, Pollak MN, Thompson AM, Roy PG, ... ... Harris AL, et al. Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin. British Journal of Cancer. PMID 31819193 DOI: 10.1038/s41416-019-0665-5 |
0.802 |
|
2019 |
Kawashima M, Tokiwa M, Nishimura T, Kawata Y, Sugimoto M, Kataoka TR, Sakurai T, Iwaisako K, Suzuki E, Hagiwara M, Harris AL, Toi M. High-resolution imaging mass spectrometry combined with transcriptomic analysis identified a link between fatty acid composition of phosphatidylinositols and the immune checkpoint pathway at the primary tumour site of breast cancer. British Journal of Cancer. PMID 31819188 DOI: 10.1038/s41416-019-0662-8 |
0.449 |
|
2019 |
Favara DM, Zois CE, Haider S, Pires E, Sheldon H, McCullagh J, Banham AH, Harris AL. ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile. Metabolites. 9. PMID 31775252 DOI: 10.3390/metabo9120287 |
0.801 |
|
2019 |
Masiero M, Li D, Whiteman P, Bentley C, Greig J, Hassanali T, Watts S, Stribbling S, Yates J, Bealing E, Li JL, Chillakuri C, Sheppard D, Serres S, Sarmiento-Soto M, ... ... Harris AL, et al. Development of therapeutic anti-JAGGED1 antibodies for cancer therapy. Molecular Cancer Therapeutics. PMID 31395687 DOI: 10.1158/1535-7163.Mct-18-1176 |
0.683 |
|
2019 |
Giatromanolaki A, Koukourakis IM, Balaska K, Mitrakas AG, Harris AL, Koukourakis MI. Programmed death-1 receptor (PD-1) and PD-ligand-1 (PD-L1) expression in non-small cell lung cancer and the immune-suppressive effect of anaerobic glycolysis. Medical Oncology (Northwood, London, England). 36: 76. PMID 31342270 DOI: 10.1007/s12032-019-1299-4 |
0.424 |
|
2019 |
Fox NS, Haider S, Harris AL, Boutros PC. Landscape of transcriptomic interactions between breast cancer and its microenvironment. Nature Communications. 10: 3116. PMID 31308365 DOI: 10.1038/s41467-019-10929-z |
0.517 |
|
2019 |
Favara DM, Banham AH, Harris AL. ADGRL4/ELTD1 is a highly conserved angiogenesis-associated orphan adhesion GPCR that emerged with the first vertebrates and comprises 3 evolutionary variants. Bmc Evolutionary Biology. 19: 143. PMID 31299890 DOI: 10.1186/s12862-019-1445-9 |
0.746 |
|
2019 |
Morotti M, Bridges E, Valli A, Choudhry H, Sheldon H, Wigfield S, Gray N, Zois CE, Grimm F, Jones D, Teoh EJ, Cheng WC, Lord S, Anastasiou D, Haider S, ... ... Harris AL, et al. Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 31152137 DOI: 10.1073/Pnas.1818521116 |
0.83 |
|
2019 |
Giatromanolaki A, Banham AH, Harris AL, Koukourakis MI. FOXP3 infiltrating lymphocyte density and PD-L1 expression in operable non-small cell lung carcinoma. Experimental Lung Research. 1-8. PMID 31134811 DOI: 10.1080/01902148.2019.1617371 |
0.482 |
|
2019 |
Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, ... ... Harris AL, et al. Adaptation to HIF1α deletion in hypoxic cancer cells by upregulation of GLUT14 and creatine metabolism. Molecular Cancer Research : McR. PMID 30885992 DOI: 10.1158/1541-7786.MCR-18-0315 |
0.812 |
|
2018 |
Jones DT, Valli A, Haider S, Zhang Q, Smethurst EA, Schug ZT, Peck B, Aboagye EO, Critchlow SE, Schulze A, Gottlieb E, Wakelam MJO, Harris AL. 3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers. Molecular Cancer Therapeutics. 18: 376-388. PMID 30478149 DOI: 10.1158/1535-7163.MCT-17-0857 |
0.795 |
|
2018 |
Lord SR, Cheng WC, Liu D, Gaude E, Haider S, Metcalf T, Patel N, Teoh EJ, Gleeson F, Bradley K, Wigfield S, Zois C, McGowan DR, Ah-See ML, Thompson AM, ... ... Harris AL, et al. Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer. Cell Metabolism. PMID 30244975 DOI: 10.1016/J.Cmet.2018.08.021 |
0.812 |
|
2018 |
Lee SH, McIntyre D, Honess D, Hulikova A, Pacheco-Torres J, Cerdán S, Swietach P, Harris AL, Griffiths JR. Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo. British Journal of Cancer. PMID 30206370 DOI: 10.1038/S41416-018-0216-5 |
0.58 |
|
2018 |
Leithner K, Triebl A, Trötzmüller M, Hinteregger B, Leko P, Wieser BI, Grasmann G, Bertsch AL, Züllig T, Stacher E, Valli A, Prassl R, Olschewski A, Harris AL, Köfeler HC, et al. The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29844165 DOI: 10.1073/pnas.1719871115 |
0.716 |
|
2018 |
Schuh A, Dreau H, Knight SJL, Ridout K, Mizani T, Vavoulis D, Colling R, Antoniou P, Kvikstad EM, Pentony MM, Hamblin A, Protheroe A, Parton M, Shah KA, Orosz Z, ... ... Harris A, et al. Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing. Cold Spring Harbor Molecular Case Studies. 4. PMID 29610388 DOI: 10.1101/mcs.a002279 |
0.57 |
|
2018 |
Donnem T, Reynolds AR, Kuczynski EA, Gatter K, Vermeulen PB, Kerbel RS, Harris AL, Pezzella F. Non-angiogenic tumours and their influence on cancer biology. Nature Reviews. Cancer. PMID 29520090 DOI: 10.1038/Nrc.2018.14 |
0.554 |
|
2018 |
Woodcock VK, Clive S, Wilson RH, Coyle VM, Stratford MRL, Folkes LK, Eastell R, Barton C, Jones P, Kazmi-Stokes S, Turner H, Halford S, Harris AL, Middleton MR. A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424. British Journal of Cancer. PMID 29438361 DOI: 10.1038/bjc.2017.484 |
0.536 |
|
2018 |
Koukourakis MI, Giatromanolaki A, Fylaktakidou K, Sivridis E, Zois CE, Kalamida D, Mitrakas A, Pouliliou S, Karagounis IV, Simopoulos K, Ferguson DJP, Harris AL. SMER28 is a mTOR-independent small molecule enhancer of autophagy that protects mouse bone morrow and liver against radiotherapy. Investigational New Drugs. PMID 29387992 DOI: 10.1007/s10637-018-0566-0 |
0.459 |
|
2018 |
Yang J, Harris AL, Davidoff AM. Hypoxia and Hormone-Mediated Pathways Converge at the Histone Demethylase KDM4B in Cancer. International Journal of Molecular Sciences. 19. PMID 29342868 DOI: 10.3390/ijms19010240 |
0.379 |
|
2018 |
Koukourakis MI, Giatromanolaki A, Fylaktakidou K, Kouroupi M, Sivridis E, Zois CE, Kalamida D, Mitrakas A, Pouliliou S, Karagounis IV, Simopoulos K, Ferguson DJP, Harris AL. Amifostine Protects Mouse Liver Against Radiation-induced Autophagy Blockage. Anticancer Research. 38: 227-238. PMID 29277777 DOI: 10.21873/anticanres.12212 |
0.415 |
|
2018 |
Dhawan A, Scott JG, Sundaresan P, Veness M, Porceddu S, Hau E, Ahern V, Harris AL, Buffa FM, Gee HE. Are signatures of radiosensitivity ready for routine clinical use? A pragmatic comparison of clinical, pathological, and gene signature predictors of outcome in oropharynx head and neck cancers. Journal of Clinical Oncology. 36: e18046-e18046. DOI: 10.1016/J.Ijrobp.2018.06.338 |
0.68 |
|
2018 |
Dhawan A, Scott J, Sundaresan P, Veness M, Porceddu S, Hau E, Ahern V, Harris A, Buffa F, Gee H. Are Signatures of Radiosensitivity Ready for Routine Clinical Use? a Pragmatic Comparison of Clinical, Pathological and Gene Signature Predictors of Outcome in Oropharynx Head and Neck Cancers International Journal of Radiation Oncology*Biology*Physics. 102: S137-S138. DOI: 10.1016/j.ijrobp.2018.06.338 |
0.68 |
|
2017 |
Pajic M, Froio D, Daly S, Doculara L, Millar E, Graham PH, Drury A, Steinmann A, de Bock CE, Boulghourjian A, Zaratzian A, Carroll S, Toohey J, O'Toole SA, Harris AL, et al. miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense. Cancer Research. PMID 29180477 DOI: 10.1158/0008-5472.CAN-16-3105 |
0.712 |
|
2017 |
Choudhry H, Harris AL. Advances in Hypoxia-Inducible Factor Biology. Cell Metabolism. PMID 29129785 DOI: 10.1016/j.cmet.2017.10.005 |
0.607 |
|
2017 |
Milani M, Venturini S, Bonardi S, Allevi G, Strina C, Cappelletti MR, Corona SP, Aguggini S, Bottini A, Berruti A, Jubb A, Campo L, Harris AL, Gatter K, Fox SB, et al. Hypoxia-related biological markers as predictors of epirubicin-based treatment responsiveness and resistance in locally advanced breast cancer. Oncotarget. 8: 78870-78881. PMID 29108271 DOI: 10.18632/oncotarget.20239 |
0.81 |
|
2017 |
Morotti M, Dass PH, Harris AL, Lord S. Pharmacodynamic and Pharmacokinetic Markers For Anti-angiogenic Cancer Therapy: Implications for Dosing and Selection of Patients. European Journal of Drug Metabolism and Pharmacokinetics. PMID 29019020 DOI: 10.1007/s13318-017-0442-x |
0.803 |
|
2017 |
Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Harris AL, Li JL. Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth. Oncotarget. PMID 28445154 DOI: 10.18632/oncotarget.16969 |
0.81 |
|
2017 |
Erdal E, Haider S, Rehwinkel J, Harris AL, McHugh PJ. A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1. Genes & Development. PMID 28279982 DOI: 10.1101/gad.289769.116 |
0.805 |
|
2017 |
Cheng W, Choudhry H, Leszczynska K, Roberts D, Hammond E, West C, Harris A, Buffa F. Extensive global alternative splicing induced by hypoxia across four major cancer types Annals of Oncology. 28: vii25. DOI: 10.1093/annonc/mdx513 |
0.58 |
|
2016 |
Kleibeuker EA, Fokas E, Allen PD, Kersemans V, Griffioen AW, Beech J, Im JH, Smart SC, Castricum KC, van den Berg J, Schulkens IA, Hill SA, Harris AL, Slotman BJ, Verheul HM, et al. Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect. Oncotarget. PMID 27780936 DOI: 10.18632/oncotarget.12814 |
0.801 |
|
2016 |
Koukourakis MI, Giatromanolaki A, Zois CE, Kalamida D, Pouliliou S, Karagounis IV, Yeh TL, Abboud MI, Claridge TD, Schofield CJ, Sivridis E, Simopoulos C, Tokmakidis SP, Harris AL. Normal tissue radioprotection by amifostine via Warburg-type effects. Scientific Reports. 6: 30986. PMID 27507219 DOI: 10.1038/Srep30986 |
0.5 |
|
2016 |
Mehta S, Hughes NP, Li S, Jubb A, Adams R, Lord S, Koumakis L, van Stiphout R, Padhani A, Makris A, Buffa FM, Harris AL. Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment. Ebiomedicine. PMID 27474395 DOI: 10.1016/j.ebiom.2016.07.017 |
0.822 |
|
2016 |
Andreis D, Bonardi S, Allevi G, Aguggini S, Gussago F, Milani M, Strina C, Spada D, Ferrero G, Ungari M, Rocca A, Nanni O, Roviello G, Berruti A, Harris AL, et al. Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with T2 to T4, N0 and N1 breast cancer. Breast (Edinburgh, Scotland). 29: 55-61. PMID 27428471 DOI: 10.1016/j.breast.2016.07.003 |
0.737 |
|
2016 |
Haider S, McIntyre A, van Stiphout RG, Winchester LM, Wigfield S, Harris AL, Buffa FM. Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia. Genome Biology. 17: 140. PMID 27358048 DOI: 10.1186/s13059-016-0999-8 |
0.792 |
|
2016 |
Leek R, Grimes DR, Harris AL, McIntyre A. Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia. Advances in Experimental Medicine and Biology. 899: 167-96. PMID 27325267 DOI: 10.1007/978-3-319-26666-4_10 |
0.583 |
|
2016 |
da Motta LL, Ledaki I, Purshouse K, Haider S, De Bastiani MA, Baban D, Morotti M, Steers G, Wigfield S, Bridges E, Li JL, Knapp S, Ebner D, Klamt F, Harris AL, et al. The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer. Oncogene. PMID 27292261 DOI: 10.1038/onc.2016.184 |
0.835 |
|
2016 |
McIntyre A, Hulikova A, Ledaki I, Snell C, Singleton D, Steers G, Seden P, Jones D, Bridges E, Wigfield S, Li JL, Russell A, Swietach P, Harris AL. Disrupting hypoxia-induced bicarbonate transport acidifies tumor cells and suppresses tumor growth. Cancer Research. PMID 27197160 DOI: 10.1158/0008-5472.Can-15-1862 |
0.821 |
|
2016 |
Grimes DR, Kannan P, McIntyre A, Kavanagh A, Siddiky A, Wigfield S, Harris A, Partridge M. The Role of Oxygen in Avascular Tumor Growth. Plos One. 11: e0153692. PMID 27088720 DOI: 10.1371/journal.pone.0153692 |
0.713 |
|
2016 |
Peck B, Schug ZT, Zhang Q, Dankworth B, Jones DT, Smethurst E, Patel R, Mason S, Jiang M, Saunders R, Howell M, Mitter R, Spencer-Dene B, Stamp G, McGarry L, ... ... Harris AL, et al. Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments. Cancer & Metabolism. 4: 6. PMID 27042297 DOI: 10.1186/S40170-016-0146-8 |
0.627 |
|
2016 |
Lord S, Funes JM, Harris AL, Quintela-Fandino M. Antiangiogenic resistance and cancer metabolism: opportunities for synthetic lethality. Current Drug Targets. PMID 26953245 DOI: 10.2174/1389450117666160307143718 |
0.674 |
|
2016 |
Gijsen M, King P, Perera T, Parker PJ, Harris AL, Larijani B, Kong A. Correction: HER2 Phosphorylation Is Maintained by a PKB Negative Feedback Loop in Response to Anti-HER2 Herceptin in Breast Cancer. Plos Biology. 14: e1002414. PMID 26949965 DOI: 10.1371/journal.pbio.1002414 |
0.596 |
|
2016 |
Siriwardana PN, Luong TV, Watkins J, Turley H, Ghazaley M, Gatter K, Harris AL, Hochhauser D, Davidson BR. Biological and Prognostic Significance of the Morphological Types and Vascular Patterns in Colorectal Liver Metastases (CRLM): Looking Beyond the Tumor Margin. Medicine. 95: e2924. PMID 26937938 DOI: 10.1097/MD.0000000000002924 |
0.618 |
|
2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Harris AL, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886 |
0.362 |
|
2016 |
Adighibe O, Leek RD, Fernandez-Mercado M, Hu J, Snell C, Gatter KC, Harris AL, Pezzella F. Why some tumours trigger neovascularisation and others don't: the story thus far. Chinese Journal of Cancer. 35: 18. PMID 26873439 DOI: 10.1186/s40880-016-0082-6 |
0.814 |
|
2016 |
Chen L, Zeng X, Kleibeuker E, Buffa F, Barberis A, Leek RD, Roxanis I, Zhang W, Worth A, Beech JS, Harris AL, Cai S. Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth. Oncotarget. PMID 26814432 DOI: 10.18632/oncotarget.6981 |
0.834 |
|
2016 |
Choudhry H, Harris AL, McIntyre A. The tumour hypoxia induced non-coding transcriptome. Molecular Aspects of Medicine. PMID 26806607 DOI: 10.1016/j.mam.2016.01.003 |
0.578 |
|
2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Harris AL, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.422 |
|
2016 |
Choudhry H, Albukhari A, Morotti M, Haider S, Moralli D, Schödel J, Green C, Camps C, Buffa F, Ratcliffe P, Ragoussis I, Mole D, Harris A. Abstract A29: Hypoxia regulated long noncoding RNAs and antisense transcripts in breast cancer: Novel insights of noncoding transcriptional regulation in hypoxic microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-A29 |
0.826 |
|
2016 |
Siriwardana P, Luong T, Watkins J, Turley H, Ong W, Gatter K, Hochhauser D, Harris A, Davidson B. Ten-year follow up case-control study of the effect of portal vein embolisation on the survival of patients with colorectal liver metastases; the hypoxia factor influence Hpb. 18: e3. DOI: 10.1016/J.HPB.2016.02.014 |
0.529 |
|
2016 |
Lord S, Liu D, Cheng W, Haider S, Gaude E, Teoh E, Patel N, Metcalf T, McGowan D, Roxanis I, Qifeng Z, Roy P, Gleeson F, Thompson A, Pollak M, ... ... Harris A, et al. Metformin increases 18F-FDG flux and inhibits fatty acid oxidation at clinical doses in breast cancer: Results of a phase 0 clinical trial European Journal of Surgical Oncology (Ejso). 42: S230. DOI: 10.1016/J.Ejso.2016.07.060 |
0.698 |
|
2015 |
Pezzella F, Harris AL, Tavassoli M, Gatter KC. Blood vessels and cancer much more than just angiogenesis. Cell Death Discovery. 1: 15064. PMID 27551488 DOI: 10.1038/cddiscovery.2015.64 |
0.549 |
|
2015 |
Zhang X, Gee H, Rose B, Lee CS, Clark J, Elliott M, Gamble JR, Cairns MJ, Harris A, Khoury S, Tran N. Regulation of the tumour suppressor PDCD4 by miR-499 and miR-21 in oropharyngeal cancers. Bmc Cancer. 16: 86. PMID 26867589 DOI: 10.1186/s12885-016-2109-4 |
0.707 |
|
2015 |
Biziota E, Briasoulis E, Mavroeidis L, Marselos M, Harris AL, Pappas P. Cellular and molecular effects of metronomic vinorelbine and 4-O-deacetylvinorelbine on human umbilical vein endothelial cells. Anti-Cancer Drugs. PMID 26629767 DOI: 10.1097/CAD.0000000000000319 |
0.805 |
|
2015 |
Yang J, AlTahan A, Jones DT, Buffa FM, Bridges E, Interiano RB, Qu C, Vogt N, Li JL, Baban D, Ragoussis J, Nicholson R, Davidoff AM, Harris AL. Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598706 DOI: 10.1073/pnas.1422015112 |
0.768 |
|
2015 |
Gee HE, Buffa FM, Harris AL, Toohey JM, Carroll SL, Cooper CL, Beith J, McNeil C, Carmalt H, Mak C, Warrier S, Holliday A, Selinger C, Beckers R, Kennedy C, et al. MicroRNA-Related DNA Repair/Cell-Cycle Genes Independently Associated With Relapse After Radiation Therapy for Early Breast Cancer. International Journal of Radiation Oncology, Biology, Physics. 93: 1104-14. PMID 26581147 DOI: 10.1016/j.ijrobp.2015.08.046 |
0.721 |
|
2015 |
Fan SJ, Snell C, Turley H, Li JL, McCormick R, Perera SM, Heublein S, Kazi S, Azad A, Wilson C, Harris AL, Goberdhan DC. PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer. Oncogene. PMID 26434594 DOI: 10.1038/onc.2015.363 |
0.605 |
|
2015 |
Koukourakis MI, Kalamida D, Giatromanolaki A, Zois CE, Sivridis E, Pouliliou S, Mitrakas A, Gatter KC, Harris AL. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines. Plos One. 10: e0137675. PMID 26378792 DOI: 10.1371/journal.pone.0137675 |
0.471 |
|
2015 |
Ledaki I, McIntyre A, Wigfield S, Buffa F, McGowan S, Baban D, Li JL, Harris AL. Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. Oncotarget. 6: 19413-27. PMID 26305601 |
0.82 |
|
2015 |
Choudhry H, Albukhari A, Morotti M, Haider S, Moralli D, Smythies J, Schödel J, Green CM, Camps C, Buffa F, Ratcliffe P, Ragoussis J, Harris AL, Mole DR. Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival. Oncogene. 34: 4546. PMID 26289678 DOI: 10.1038/onc.2014.431 |
0.815 |
|
2015 |
Giatromanolaki A, Kalamida D, Sivridis E, Karagounis IV, Gatter KC, Harris AL, Koukourakis MI. Increased expression of transcription factor EB (TFEB) is associated with autophagy, migratory phenotype and poor prognosis in non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 90: 98-105. PMID 26264650 DOI: 10.1016/j.lungcan.2015.07.008 |
0.487 |
|
2015 |
Blick C, Ramachandran A, McCormick R, Wigfield S, Cranston D, Catto J, Harris AL. Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis. British Journal of Cancer. 113: 634-44. PMID 26196183 DOI: 10.1038/bjc.2015.203 |
0.797 |
|
2015 |
Valli A, Harris AL, Kessler BM. Hypoxia metabolism in ageing. Aging. 7: 465-6. PMID 26187134 |
0.661 |
|
2015 |
Amoroso V, Generali D, Buchholz T, Cristofanilli M, Pedersini R, Curigliano G, Daidone MG, Di Cosimo S, Dowsett M, Fox S, Harris AL, Makris A, Vassalli L, Ravelli A, Cappelletti MR, et al. International Expert Consensus on Primary Systemic Therapy in the Management of Early Breast Cancer: Highlights of the Fifth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2013). Journal of the National Cancer Institute. Monographs. 2015: 90-6. PMID 26063896 DOI: 10.1093/jncimonographs/lgv023 |
0.604 |
|
2015 |
Lord SR, Patel N, Liu D, Fenwick J, Gleeson F, Buffa F, Harris AL. Neoadjuvant Window Studies of Metformin and Biomarker Development for Drugs Targeting Cancer Metabolism. Journal of the National Cancer Institute. Monographs. 2015: 81-6. PMID 26063894 DOI: 10.1093/jncimonographs/lgv011 |
0.662 |
|
2015 |
Generali D, Berruti A, Cappelletti MR, Zanotti L, Brugnoli G, Forti M, Bedussi F, Vailati ME, Milani M, Strina C, Ardine M, Aguggini S, Allevi G, Ferrero G, Bertoni R, ... ... Harris AL, et al. Effect of Primary Letrozole Treatment on Tumor Expression of mTOR and HIF-1α and Relation to Clinical Response. Journal of the National Cancer Institute. Monographs. 2015: 64-6. PMID 26063890 DOI: 10.1093/jncimonographs/lgv018 |
0.796 |
|
2015 |
Chiorean EG, LoRusso P, Strother RM, Diamond JR, Younger A, Messersmith WA, Adriaens L, Liu L, Kao RJ, DiCioccio AT, Kostic A, Leek R, Harris A, Jimeno A. A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2695-703. PMID 25724527 DOI: 10.1158/1078-0432.Ccr-14-2797 |
0.582 |
|
2015 |
McIntyre A, Harris AL. Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality. Embo Molecular Medicine. 7: 368-79. PMID 25700172 DOI: 10.15252/emmm.201404271 |
0.302 |
|
2015 |
Leung WY, Roxanis I, Sheldon H, Buffa FM, Li JL, Harris AL, Kong A. Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer. Oncotarget. 6: 5678-94. PMID 25691057 |
0.772 |
|
2015 |
Lewis CA, Brault C, Peck B, Bensaad K, Griffiths B, Mitter R, Chakravarty P, East P, Dankworth B, Alibhai D, Harris AL, Schulze A. SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme. Oncogene. PMID 25619842 DOI: 10.1038/onc.2014.439 |
0.302 |
|
2015 |
Valli A, Rodriguez M, Moutsianas L, Fischer R, Fedele V, Huang HL, Van Stiphout R, Jones D, Mccarthy M, Vinaxia M, Igarashi K, Sato M, Soga T, Buffa F, Mccullagh J, ... ... Harris A, et al. Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways. Oncotarget. 6: 1920-41. PMID 25605240 DOI: 10.18632/Oncotarget.3058 |
0.793 |
|
2015 |
Schug ZT, Peck B, Jones DT, Zhang Q, Grosskurth S, Alam IS, Goodwin LM, Smethurst E, Mason S, Blyth K, McGarry L, James D, Shanks E, Kalna G, Saunders RE, ... ... Harris AL, et al. Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress. Cancer Cell. 27: 57-71. PMID 25584894 DOI: 10.1016/J.Ccell.2014.12.002 |
0.634 |
|
2015 |
Fleming IN, Manavaki R, Blower PJ, West C, Williams KJ, Harris AL, Domarkas J, Lord S, Baldry C, Gilbert FJ. Imaging tumour hypoxia with positron emission tomography. British Journal of Cancer. 112: 238-50. PMID 25514380 DOI: 10.1038/bjc.2014.610 |
0.625 |
|
2015 |
Bazzola L, Foroni C, Andreis D, Zanoni V, R Cappelletti M, Allevi G, Aguggini S, Strina C, Milani M, Venturini S, Ferrozzi F, Giardini R, Bertoni R, Turley H, Gatter K, ... ... Harris AL, et al. Combination of letrozole, metronomic cyclophosphamide and sorafenib is well-tolerated and shows activity in patients with primary breast cancer. British Journal of Cancer. 112: 52-60. PMID 25461806 DOI: 10.1038/bjc.2014.563 |
0.811 |
|
2015 |
Harris BHL, Wigfield S, Harris AL, Buffa FM. Bioinformatic approaches elucidate a high likelyhood of interaction between miR-182 and the pro-apoptotic gene MTCH2 in breast cancers. Journal of Clinical Oncology. 33: e12551-e12551. DOI: 10.1200/jco.2015.33.15_suppl.e12551 |
0.714 |
|
2015 |
Choudhry H, Schodel J, Albukhari A, Haider S, Buffa F, Ratcliffe PJ, Mole DR, Ragousis I, Harris AL. Abstract P2-05-01: The non-coding transcriptome of hypoxic breast cancer: Novel insights of clinical relevant long non-coding RNA in hypoxia signalling Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P2-05-01 |
0.707 |
|
2015 |
Stevens D, Verrill C, Bryant R, McKee C, Turley H, Fan S, Perera S, Wilson C, Harris AL, Hamdy FC, Goberdhan DC. MP55-12 THE PROTON-ASSISTED AMINO ACID TRANSPORTER 4 (PAT4/SLC36A4) IS UP-REGULATED IN PROSTATE CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2055 |
0.572 |
|
2014 |
Kato T, Pezzella F, Steers G, Campo L, Leek RD, Turley H, Kameoka S, Nishikawa T, Harris AL, Gatter KC, Fox S. Blood vessel invasion and other variables as predictors of long-term survival in Japanese and British patients with primary invasive breast cancer. International Journal of Clinical and Experimental Pathology. 7: 7967-78. PMID 25550840 |
0.807 |
|
2014 |
Singleton DC, Rouhi P, Zois CE, Haider S, Li JL, Kessler BM, Cao Y, Harris AL. Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis. Oncogene. PMID 25486436 DOI: 10.1038/onc.2014.396 |
0.819 |
|
2014 |
Giatromanolaki A, Sivridis E, Mitrakas A, Kalamida D, Zois CE, Haider S, Piperidou C, Pappa A, Gatter KC, Harris AL, Koukourakis MI. Autophagy and lysosomal related protein expression patterns in human glioblastoma. Cancer Biology & Therapy. 15: 1468-78. PMID 25482944 DOI: 10.4161/15384047.2014.955719 |
0.641 |
|
2014 |
Choudhry H, Albukhari A, Morotti M, Hider S, Moralli D, Smythies J, Schödel J, Green CM, Camps C, Buffa F, Ratcliffe P, Ragoussis J, Harris AL, Mole DR. Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival. Oncogene. PMID 25417700 DOI: 10.1038/Onc.2014.378 |
0.836 |
|
2014 |
Favara DM, Banham AH, Harris AL. A review of ELTD1, a pro-angiogenic adhesion GPCR. Biochemical Society Transactions. 42: 1658-64. PMID 25399586 DOI: 10.1042/BST20140216 |
0.768 |
|
2014 |
van den Beucken T, Koch E, Chu K, Rupaimoole R, Prickaerts P, Adriaens M, Voncken JW, Harris AL, Buffa FM, Haider S, Starmans MH, Yao CQ, Ivan M, Ivan C, Pecot CV, et al. Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER. Nature Communications. 5: 5203. PMID 25351418 DOI: 10.1038/Ncomms6203 |
0.556 |
|
2014 |
Pettersen EO, Ebbesen P, Gieling RG, Williams KJ, Dubois L, Lambin P, Ward C, Meehan J, Kunkler IH, Langdon SP, Ree AH, Flatmark K, Lyng H, Calzada MJ, Peso LD, ... ... Harris AL, et al. Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-33. PMID 25347767 DOI: 10.3109/14756366.2014.966704 |
0.805 |
|
2014 |
Li D, Masiero M, Banham AH, Harris AL. The notch ligand JAGGED1 as a target for anti-tumor therapy. Frontiers in Oncology. 4: 254. PMID 25309874 DOI: 10.3389/fonc.2014.00254 |
0.321 |
|
2014 |
Adighibe O, Turley H, Leek R, Harris A, Coutts AS, La Thangue N, Gatter K, Pezzella F. JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues. Virchows Archiv : An International Journal of Pathology. 465: 715-22. PMID 25280461 DOI: 10.1007/s00428-014-1660-0 |
0.803 |
|
2014 |
Bensaad K, Favaro E, Lewis CA, Peck B, Lord S, Collins JM, Pinnick KE, Wigfield S, Buffa FM, Li JL, Zhang Q, Wakelam MJ, Karpe F, Schulze A, Harris AL. Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation. Cell Reports. 9: 349-65. PMID 25263561 DOI: 10.1016/j.celrep.2014.08.056 |
0.797 |
|
2014 |
Zois CE, Favaro E, Harris AL. Glycogen metabolism in cancer. Biochemical Pharmacology. 92: 3-11. PMID 25219323 DOI: 10.1016/j.bcp.2014.09.001 |
0.741 |
|
2014 |
Mohd Nafi SN, Generali D, Kramer-Marek G, Gijsen M, Strina C, Cappelletti M, Andreis D, Haider S, Li JL, Bridges E, Capala J, Ioannis R, Harris AL, Kong A. Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer. Oncotarget. 5: 5934-49. PMID 25153719 |
0.816 |
|
2014 |
Hulikova A, Aveyard N, Harris AL, Vaughan-Jones RD, Swietach P. Intracellular carbonic anhydrase activity sensitizes cancer cell pH signaling to dynamic changes in CO2 partial pressure. The Journal of Biological Chemistry. 289: 25418-30. PMID 25059669 DOI: 10.1074/jbc.M114.547844 |
0.619 |
|
2014 |
Feldinger K, Generali D, Kramer-Marek G, Gijsen M, Ng TB, Wong JH, Strina C, Cappelletti M, Andreis D, Li JL, Bridges E, Turley H, Leek R, Roxanis I, Capala J, ... ... Harris AL, et al. ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer. Oncotarget. 5: 6633-46. PMID 24952873 |
0.815 |
|
2014 |
Harjes U, Bridges E, McIntyre A, Fielding BA, Harris AL. Fatty acid-binding protein 4, a point of convergence for angiogenic and metabolic signaling pathways in endothelial cells. The Journal of Biological Chemistry. 289: 23168-76. PMID 24939870 DOI: 10.1074/jbc.M114.576512 |
0.655 |
|
2014 |
Generali D, Buffa FM, Deb S, Cummings M, Reid LE, Taylor M, Andreis D, Allevi G, Ferrero G, Byrne D, Martinotti M, Bottini A, Harris AL, Lakhani SR, Fox SB. COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment. British Journal of Cancer. 111: 46-54. PMID 24874483 DOI: 10.1038/bjc.2014.236 |
0.609 |
|
2014 |
Pezzella F, Harris AL. When cancer co-opts the vasculature. The New England Journal of Medicine. 370: 2146-7. PMID 24869725 DOI: 10.1056/NEJMcibr1402407 |
0.552 |
|
2014 |
Favara DM, Harris AL. VEGF sticky-trap: the first report of a non-systemically acting angiogenesis inhibitor. Embo Molecular Medicine. 6: 577-9. PMID 24803395 DOI: 10.1002/emmm.201404026 |
0.736 |
|
2014 |
Koukourakis MI, Giatromanolaki A, Bottini A, Cappelletti MR, Zanotti L, Allevi G, Strina C, Ardine M, Milani M, Brugnoli G, Martinotti M, Ferrero G, Bertoni R, Ferrozzi F, Harris AL, et al. Prospective neoadjuvant analysis of PET imaging and mechanisms of resistance to Trastuzumab shows role of HIF1 and autophagy. British Journal of Cancer. 110: 2209-16. PMID 24722179 DOI: 10.1038/bjc.2014.196 |
0.797 |
|
2014 |
Interiano RB, Yang J, Harris AL, Davidoff AM. Seven In Absentia Homolog 2 (SIAH2) downregulation is associated with tamoxifen resistance in MCF-7 breast cancer cells. The Journal of Surgical Research. 190: 203-9. PMID 24656476 DOI: 10.1016/j.jss.2014.02.018 |
0.373 |
|
2014 |
Agorreta J, Hu J, Liu D, Delia D, Turley H, Ferguson DJ, Iborra F, Pajares MJ, Larrayoz M, Zudaire I, Pio R, Montuenga LM, Harris AL, Gatter K, Pezzella F. TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC. Molecular Cancer Research : McR. 12: 660-9. PMID 24567527 DOI: 10.1158/1541-7786.MCR-13-0481 |
0.693 |
|
2014 |
Snell CE, Turley H, McIntyre A, Li D, Masiero M, Schofield CJ, Gatter KC, Harris AL, Pezzella F. Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours. Plos One. 9: e88955. PMID 24563687 DOI: 10.1371/Journal.Pone.0088955 |
0.836 |
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2014 |
Jiang H, Favaro E, Goulbourne CN, Rakowska PD, Hughes GM, Ryadnov MG, Fong LG, Young SG, Ferguson DJ, Harris AL, Grovenor CR. Stable isotope imaging of biological samples with high resolution secondary ion mass spectrometry and complementary techniques. Methods (San Diego, Calif.). 68: 317-24. PMID 24556558 DOI: 10.1016/j.ymeth.2014.02.012 |
0.703 |
|
2014 |
Camps C, Saini HK, Mole DR, Choudhry H, Reczko M, Guerra-Assunção JA, Tian YM, Buffa FM, Harris AL, Hatzigeorgiou AG, Enright AJ, Ragoussis J. Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia. Molecular Cancer. 13: 28. PMID 24517586 DOI: 10.1186/1476-4598-13-28 |
0.583 |
|
2014 |
Swietach P, Vaughan-Jones RD, Harris AL, Hulikova A. The chemistry, physiology and pathology of pH in cancer. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130099. PMID 24493747 DOI: 10.1098/rstb.2013.0099 |
0.591 |
|
2014 |
Airley RE, McHugh P, Evans AR, Harris B, Winchester L, Buffa FM, Al-Tameemi W, Leek R, Harris AL. Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression. British Journal of Cancer. 110: 715-23. PMID 24366300 DOI: 10.1038/bjc.2013.765 |
0.81 |
|
2014 |
Choudhry H, Schödel J, Oikonomopoulos S, Camps C, Grampp S, Harris AL, Ratcliffe PJ, Ragoussis J, Mole DR. Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2. Embo Reports. 15: 70-6. PMID 24363272 DOI: 10.1002/Embr.201337642 |
0.533 |
|
2014 |
Snell CE, Turley H, McIntyre A, Li D, Masiero M, Schofield CJ, Gatter KC, Harris AL, Pezzella F. Expression of proline-hydroxylated HIF-1α predicts poorer overall survival in primary breast cancer. Plos One. DOI: 10.1371/Journal.Pone.0088955.G005 |
0.814 |
|
2014 |
Choudhry H, Schodel J, Albukhari A, Oikonomopoulos S, Haider S, Buffa F, Ragousis I, Mole DR, Harris AL. Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-P40 |
0.672 |
|
2014 |
Choudhry H, Schodel J, Albukhari A, Oikonomopoulos S, Haider S, Buffa F, Ragousis I, Mole DR, Harris AL. Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-O17 |
0.691 |
|
2014 |
Choudhry H, Schodel J, Albukhari A, Oikonomopoulos S, Haider S, Moralli D, Camps C, Buffa F, Ratcliffe P, Ragousis I, Mole DR, Harris AL. Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer Bmc Genomics. 15. DOI: 10.1186/1471-2164-15-S2-O17 |
0.672 |
|
2014 |
Oon CE, Bridges E, Sheldon H, Sainson RCA, Jubb A, Turley H, Leek R, Buffa F, Li JL, Harris AL. Functional comparison of Notch ligands in tumour angiogenesis Asian Pacific Journal of Tropical Disease. 4: 229. DOI: 10.1016/S2222-1808(14)60523-5 |
0.779 |
|
2014 |
Jiang H, Favaro E, Goulbourne CN, Ferguson DJ, Young SG, Harris AL, Grovenor CR. Quantitatively Imaging Stable Isotopes at Subcellular Level with Correlative Electron Microscopy and Nanosims Analysis Biophysical Journal. 106: 597a-598a. DOI: 10.1016/J.BPJ.2013.11.3309 |
0.685 |
|
2013 |
Donnem T, Hu J, Ferguson M, Adighibe O, Snell C, Harris AL, Gatter KC, Pezzella F. Vessel co-option in primary human tumors and metastases: an obstacle to effective anti-angiogenic treatment? Cancer Medicine. 2: 427-36. PMID 24156015 DOI: 10.1002/cam4.105 |
0.753 |
|
2013 |
Horsley L, Cummings J, Middleton M, Ward T, Backen A, Clamp A, Dawson M, Farmer H, Fisher N, Halbert G, Halford S, Harris A, Hasan J, Hogg P, Kumaran G, et al. A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours. Cancer Chemotherapy and Pharmacology. 72: 1343-52. PMID 24141375 DOI: 10.1007/s00280-013-2320-9 |
0.665 |
|
2013 |
Nikitenko LL, Leek R, Henderson S, Pillay N, Turley H, Generali D, Gunningham S, Morrin HR, Pellagatti A, Rees MC, Harris AL, Fox SB. The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5740-8. PMID 23969937 DOI: 10.1158/1078-0432.CCR-13-1712 |
0.811 |
|
2013 |
Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, ... ... Harris AL, et al. A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. Cancer Cell. 24: 229-41. PMID 23871637 DOI: 10.1016/J.Ccr.2013.06.004 |
0.811 |
|
2013 |
Bazan-Peregrino M, Sainson RC, Carlisle RC, Thoma C, Waters RA, Arvanitis C, Harris AL, Hernandez-Alcoceba R, Seymour LW. Combining virotherapy and angiotherapy for the treatment of breast cancer. Cancer Gene Therapy. 20: 461-8. PMID 23846253 DOI: 10.1038/Cgt.2013.41 |
0.74 |
|
2013 |
Blick C, Ramachandran A, Wigfield S, McCormick R, Jubb A, Buffa FM, Turley H, Knowles MA, Cranston D, Catto J, Harris AL. Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer. British Journal of Cancer. 109: 50-9. PMID 23778527 DOI: 10.1038/bjc.2013.240 |
0.801 |
|
2013 |
Eustace A, Irlam JJ, Taylor J, Denley H, Agrawal S, Choudhury A, Ryder D, Ord JJ, Harris AL, Rojas AM, Hoskin PJ, West CM. Necrosis predicts benefit from hypoxia-modifying therapy in patients with high risk bladder cancer enrolled in a phase III randomised trial. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 108: 40-7. PMID 23773411 DOI: 10.1016/j.radonc.2013.05.017 |
0.791 |
|
2013 |
Giatromanolaki A, Koukourakis MI, Pouliliou S, Gatter KC, Pezzella F, Harris AL, Sivridis E. Overexpression of LC3A autophagy protein in follicular and diffuse large B-cell lymphomas. Hematology/Oncology and Stem Cell Therapy. 6: 20-5. PMID 23664601 DOI: 10.1016/j.hemonc.2013.02.001 |
0.654 |
|
2013 |
Singleton DC, Harris AL. Microenvironmental induced essentiality of autophagy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2791-3. PMID 23613319 DOI: 10.1158/1078-0432.CCR-13-0634 |
0.742 |
|
2013 |
Allevi G, Strina C, Andreis D, Zanoni V, Bazzola L, Bonardi S, Foroni C, Milani M, Cappelletti MR, Gussago F, Aguggini S, Giardini R, Martinotti M, Fox SB, Harris AL, et al. Increased pathological complete response rate after a long-term neoadjuvant letrozole treatment in postmenopausal oestrogen and/or progesterone receptor-positive breast cancer. British Journal of Cancer. 108: 1587-92. PMID 23579222 DOI: 10.1038/bjc.2013.151 |
0.764 |
|
2013 |
Ong CC, Jubb AM, Jakubiak D, Zhou W, Rudolph J, Haverty PM, Kowanetz M, Yan Y, Tremayne J, Lisle R, Harris AL, Friedman LS, Belvin M, Middleton MR, Blackwood EM, et al. P21-activated kinase 1 (PAK1) as a therapeutic target in BRAF wild-type melanoma. Journal of the National Cancer Institute. 105: 606-7. PMID 23535073 DOI: 10.1093/Jnci/Djt054 |
0.64 |
|
2013 |
McCormick RI, Blick C, Ragoussis J, Schoedel J, Mole DR, Young AC, Selby PJ, Banks RE, Harris AL. miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis. British Journal of Cancer. 108: 1133-42. PMID 23449350 DOI: 10.1038/bjc.2013.56 |
0.665 |
|
2013 |
Favaro E, Harris AL. Targeting glycogen metabolism: a novel strategy to inhibit cancer cell growth? Oncotarget. 4: 3-4. PMID 23448808 |
0.752 |
|
2013 |
Kumar K, Wigfield S, Gee HE, Devlin CM, Singleton D, Li JL, Buffa F, Huffman M, Sinn AL, Silver J, Turley H, Leek R, Harris AL, Ivan M. Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. Journal of Molecular Medicine (Berlin, Germany). 91: 749-58. PMID 23361368 DOI: 10.1007/s00109-013-0996-2 |
0.796 |
|
2013 |
Ramachandran A, Betts G, Bhana S, Helme G, Blick C, Moller-Levet C, Saunders E, Valentine H, Pepper S, Miller CJ, Buffa F, Harris AL, West CM. An in vivo hypoxia metagene identifies the novel hypoxia inducible factor target gene SLCO1B3. European Journal of Cancer (Oxford, England : 1990). 49: 1741-51. PMID 23352438 DOI: 10.1016/j.ejca.2012.12.003 |
0.677 |
|
2013 |
Giatromanolaki A, Koukourakis MI, Koutsopoulos AV, Harris AL, Gatter KC, Sivridis E. Autophagy and hypoxia in colonic adenomas related to aggressive features. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland. 15: e223-30. PMID 23351172 DOI: 10.1111/codi.12147 |
0.49 |
|
2013 |
Whiteman P, de Madrid BH, Taylor P, Li D, Heslop R, Viticheep N, Tan JZ, Shimizu H, Callaghan J, Masiero M, Li JL, Banham AH, Harris AL, Lea SM, Redfield C, et al. Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor. The Journal of Biological Chemistry. 288: 7305-12. PMID 23339193 DOI: 10.1074/jbc.M112.428854 |
0.568 |
|
2013 |
Gieling RG, Parker CA, De Costa LA, Robertson N, Harris AL, Stratford IJ, Williams KJ. Inhibition of carbonic anhydrase activity modifies the toxicity of doxorubicin and melphalan in tumour cells in vitro. Journal of Enzyme Inhibition and Medicinal Chemistry. 28: 360-9. PMID 23163664 DOI: 10.3109/14756366.2012.736979 |
0.748 |
|
2013 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL. High DLL4 expression in tumour-associated vessels predicts for favorable radiotherapy outcome in locally advanced squamous cell head-neck cancer (HNSCC). Angiogenesis. 16: 343-51. PMID 23108591 DOI: 10.1007/s10456-012-9318-5 |
0.523 |
|
2013 |
Pike LR, Singleton DC, Buffa F, Abramczyk O, Phadwal K, Li JL, Simon AK, Murray JT, Harris AL. Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival. The Biochemical Journal. 449: 389-400. PMID 23078367 DOI: 10.1042/Bj20120972 |
0.829 |
|
2013 |
Betts GN, Eustace A, Patiar S, Valentine HR, Irlam J, Ramachandran A, Merve A, Homer JJ, Möller-Levet C, Buffa FM, Hall G, Miller CJ, Harris AL, West CM. Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma. European Journal of Cancer (Oxford, England : 1990). 49: 156-65. PMID 22951015 DOI: 10.1016/j.ejca.2012.07.028 |
0.766 |
|
2013 |
Hulikova A, Harris AL, Vaughan-Jones RD, Swietach P. Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia. Journal of Cellular Physiology. 228: 743-52. PMID 22949268 DOI: 10.1002/jcp.24221 |
0.612 |
|
2013 |
Charlesworth PJS, Sullivan ME, Protheroe A, Turner GDH, Roberts ISD, Kilbey N, Harris AL, Cranston D. Changing prognosis of renal cell carcinoma: A single-centre experience over 25 years Journal of Clinical Urology. 6: 119-124. DOI: 10.1177/2051415812473912 |
0.727 |
|
2013 |
Hoeflich K, Ong C, Lyle K, Jubb A, Zhou W, Harris A, Belvin M, Friedman L, Koeppen H, Rudolph J, Staben S. Abstract A067: Targeting p21-activated kinases in breast cancer Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A067 |
0.674 |
|
2013 |
McIntyre A, Hulikova A, Ledaki I, Seden P, Turley H, Jones D, Russell A, Swietach P, Harris AL. Abstract 4053: Hypoxic trans-activation of sodium dependent bicarbonate co-transporters regulates pH in 3D spheroids and promotes growth. Cancer Research. 73: 4053-4053. DOI: 10.1158/1538-7445.Am2013-4053 |
0.817 |
|
2013 |
Harris AL, Generali D. Inhibitors of Tumor Angiogenesis Cancer Drug Design and Discovery: Second Edition. 275-317. DOI: 10.1016/B978-0-12-396521-9.00010-3 |
0.464 |
|
2013 |
Al-Ebraheem A, Geraki K, Leek R, Harris AL, Farquharson MJ. The use of bio-metal concentrations correlated with clinical prognostic factors to assess human breast tissues X-Ray Spectrometry. 42: 330-336. DOI: 10.1002/xrs.2463 |
0.581 |
|
2012 |
Favaro E, Bensaad K, Chong MG, Tennant DA, Ferguson DJ, Snell C, Steers G, Turley H, Li JL, Günther UL, Buffa FM, McIntyre A, Harris AL. Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells. Cell Metabolism. 16: 751-64. PMID 23177934 DOI: 10.1016/j.cmet.2012.10.017 |
0.814 |
|
2012 |
Pike LR, Phadwal K, Simon AK, Harris AL. ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia. Molecular Biology Reports. 39: 10811-22. PMID 23090478 DOI: 10.1007/s11033-012-1975-3 |
0.734 |
|
2012 |
Jones DT, Lechertier T, Mitter R, Herbert JM, Bicknell R, Jones JL, Li JL, Buffa F, Harris AL, Hodivala-Dilke K. Gene expression analysis in human breast cancer associated blood vessels. Plos One. 7: e44294. PMID 23056178 DOI: 10.1371/journal.pone.0044294 |
0.772 |
|
2012 |
Singleton DC, Harris AL. Targeting the ATF4 pathway in cancer therapy. Expert Opinion On Therapeutic Targets. 16: 1189-202. PMID 23009153 DOI: 10.1517/14728222.2012.728207 |
0.769 |
|
2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Harris AL, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.405 |
|
2012 |
Giatromanolaki A, Koukourakis MI, Sivridis E, Gatter KC, Trarbach T, Folprecht G, Shi MM, Lebwohl D, Jalava T, Laurent D, Meinhardt G, Harris AL. Vascular density analysis in colorectal cancer patients treated with vatalanib (PTK787/ZK222584) in the randomised CONFIRM trials. British Journal of Cancer. 107: 1044-50. PMID 22910317 DOI: 10.1038/bjc.2012.369 |
0.524 |
|
2012 |
Biswas S, Charlesworth PJ, Turner GD, Leek R, Thamboo PT, Campo L, Turley H, Dildey P, Protheroe A, Cranston D, Gatter KC, Pezzella F, Harris AL. CD31 angiogenesis and combined expression of HIF-1α and HIF-2α are prognostic in primary clear-cell renal cell carcinoma (CC-RCC), but HIFα transcriptional products are not: implications for antiangiogenic trials and HIFα biomarker studies in primary CC-RCC. Carcinogenesis. 33: 1717-25. PMID 22777959 DOI: 10.1093/carcin/bgs222 |
0.823 |
|
2012 |
Swietach P, Hulikova A, Patiar S, Vaughan-Jones RD, Harris AL. Importance of intracellular pH in determining the uptake and efficacy of the weakly basic chemotherapeutic drug, doxorubicin. Plos One. 7: e35949. PMID 22563426 DOI: 10.1371/journal.pone.0035949 |
0.763 |
|
2012 |
Jones DT, Harris AL. Small-molecule inhibitors of the HIF pathway and synthetic lethal interactions. Expert Opinion On Therapeutic Targets. 16: 463-80. PMID 22512262 DOI: 10.1517/14728222.2012.674516 |
0.601 |
|
2012 |
McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, Turley H, Leek R, Snell C, Gatter K, Sly WS, Vaughan-Jones RD, Swietach P, Harris AL. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3100-11. PMID 22498007 DOI: 10.1158/1078-0432.CCR-11-1877 |
0.822 |
|
2012 |
Cavazzoni A, Bonelli MA, Fumarola C, La Monica S, Airoud K, Bertoni R, Alfieri RR, Galetti M, Tramonti S, Galvani E, Harris AL, Martin LA, Andreis D, Bottini A, Generali D, et al. Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. Cancer Letters. 323: 77-87. PMID 22484466 DOI: 10.1016/j.canlet.2012.03.034 |
0.539 |
|
2012 |
Hulikova A, Harris AL, Vaughan-Jones RD, Swietach P. Acid-extrusion from tissue: the interplay between membrane transporters and pH buffers. Current Pharmaceutical Design. 18: 1331-7. PMID 22360560 |
0.586 |
|
2012 |
Jubb AM, Browning L, Campo L, Turley H, Steers G, Thurston G, Harris AL, Ansorge O. Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma. Histopathology. 60: 740-7. PMID 22296176 DOI: 10.1111/j.1365-2559.2011.04138.x |
0.753 |
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2012 |
Yang J, Staples O, Thomas LW, Briston T, Robson M, Poon E, Simões ML, El-Emir E, Buffa FM, Ahmed A, Annear NP, Shukla D, Pedley BR, Maxwell PH, Harris AL, et al. Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression. The Journal of Clinical Investigation. 122: 600-11. PMID 22214851 DOI: 10.1172/Jci58780 |
0.381 |
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2012 |
Rzymski T, Petry A, KraÄun D, Rieß F, Pike L, Harris AL, Görlach A. The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress. Oncogene. 31: 3621-34. PMID 22105359 DOI: 10.1038/onc.2011.522 |
0.815 |
|
2012 |
Giatromanolaki A, Sivridis E, Bechrakis NE, Willerding G, St Charitoudis G, Foerster MH, Gatter KC, Harris AL, Koukourakis MI. Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival. Clinical & Experimental Metastasis. 29: 11-7. PMID 21984395 DOI: 10.1007/s10585-011-9424-6 |
0.551 |
|
2012 |
Mehta S, Hughes NP, Jubb AM, Turley H, Han C, Li SP, Taylor NJ, Padhani AR, Adams RF, Makris A, Harris AL. Early changes in angiogenesis and hypoxia following bevacizumab therapy in primary breast cancer. Journal of Clinical Oncology. 30: 1066-1066. DOI: 10.1200/JCO.2012.30.15_SUPPL.1066 |
0.765 |
|
2012 |
Ong C, Jubb A, Haverty P, Zhou W, Lyle K, Harris A, Belvin M, Friedman L, Koeppen H, Hoeflich KP. Abstract 4004: P21-activated kinases (PAKs) are novel therapeutic targets in human breast cancer Cancer Research. 72: 4004-4004. DOI: 10.1158/1538-7445.Am2012-4004 |
0.689 |
|
2012 |
Ong CC, Jubb AM, Haverty PM, Zhou W, Harris AL, Belvin M, Friedman LS, Koeppen H, Hoeflich KP. Abstract B8: Targeting p21-activated kinases in human lung cancer Clinical Cancer Research. 18: B8-B8. DOI: 10.1158/1078-0432.12Aacriaslc-B8 |
0.647 |
|
2011 |
Oon CE, Harris AL. New pathways and mechanisms regulating and responding to Delta-like ligand 4-Notch signalling in tumour angiogenesis. Biochemical Society Transactions. 39: 1612-8. PMID 22103496 DOI: 10.1042/BST20110721 |
0.695 |
|
2011 |
Berruti A, Generali D, Kaufmann M, Puztai L, Curigliano G, Aglietta M, Gianni L, Miller WR, Untch M, Sotiriou C, Daidone M, Conte P, Kennedy D, Damia G, Petronini P, ... ... Harris AL, et al. International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010). Journal of the National Cancer Institute. Monographs. 2011: 147-51. PMID 22043063 DOI: 10.1093/jncimonographs/lgr037 |
0.618 |
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2011 |
Mehta S, Hughes NP, Buffa FM, Li SP, Adams RF, Adwani A, Taylor NJ, Levitt NC, Padhani AR, Makris A, Harris AL. Assessing early therapeutic response to bevacizumab in primary breast cancer using magnetic resonance imaging and gene expression profiles. Journal of the National Cancer Institute. Monographs. 2011: 71-4. PMID 22043045 DOI: 10.1093/jncimonographs/lgr027 |
0.812 |
|
2011 |
Generali D, Berruti A, Foroni C, Bazzola L, Andreis D, Allevi G, Bersiga A, Dogliotti L, Fox SB, Harris AL, Bottini A. Molecular oncology and the neoadjuvant setting: the perfect blend for treatment personalization and clinical trial design. Journal of the National Cancer Institute. Monographs. 2011: 67-70. PMID 22043044 DOI: 10.1093/jncimonographs/lgr029 |
0.622 |
|
2011 |
Liu SK, Bham SA, Fokas E, Beech J, Im J, Cho S, Harris AL, Muschel RJ. Delta-like ligand 4-notch blockade and tumor radiation response. Journal of the National Cancer Institute. 103: 1778-98. PMID 22010178 DOI: 10.1093/Jnci/Djr419 |
0.799 |
|
2011 |
Favaro E, Lord S, Harris AL, Buffa FM. Gene expression and hypoxia in breast cancer. Genome Medicine. 3: 55. PMID 21875443 DOI: 10.1186/gm271 |
0.833 |
|
2011 |
Li JL, Sainson RC, Oon CE, Turley H, Leek R, Sheldon H, Bridges E, Shi W, Snell C, Bowden ET, Wu H, Chowdhury PS, Russell AJ, Montgomery CP, Poulsom R, ... Harris AL, et al. DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo. Cancer Research. 71: 6073-83. PMID 21803743 DOI: 10.1158/0008-5472.Can-11-1704 |
0.805 |
|
2011 |
Buffa FM, Camps C, Winchester L, Snell CE, Gee HE, Sheldon H, Taylor M, Harris AL, Ragoussis J. microRNA-associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Research. 71: 5635-45. PMID 21737487 DOI: 10.1158/0008-5472.CAN-11-0489 |
0.803 |
|
2011 |
Dubois L, Peeters S, Lieuwes NG, Geusens N, Thiry A, Wigfield S, Carta F, McIntyre A, Scozzafava A, Dogné JM, Supuran CT, Harris AL, Masereel B, Lambin P. Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 99: 424-31. PMID 21676479 DOI: 10.1016/J.Radonc.2011.05.045 |
0.738 |
|
2011 |
Ong CC, Jubb AM, Zhou W, Haverty PM, Harris AL, Belvin M, Friedman LS, Koeppen H, Hoeflich KP. p21-activated kinase 1: PAK'ed with potential. Oncotarget. 2: 491-6. PMID 21653999 DOI: 10.18632/Oncotarget.271 |
0.652 |
|
2011 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Trarbach T, Folprecht G, Shi MM, Lebwohl D, Jalava T, Laurent D, Meinhardt G, Harris AL. Prognostic and predictive role of lactate dehydrogenase 5 expression in colorectal cancer patients treated with PTK787/ZK 222584 (vatalanib) antiangiogenic therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4892-900. PMID 21632858 DOI: 10.1158/1078-0432.CCR-10-2918 |
0.541 |
|
2011 |
Coutts AS, Pires IM, Weston L, Buffa FM, Milani M, Li JL, Harris AL, Hammond EM, La Thangue NB. Hypoxia-driven cell motility reflects the interplay between JMY and HIF-1α. Oncogene. 30: 4835-42. PMID 21625218 DOI: 10.1038/onc.2011.188 |
0.687 |
|
2011 |
Serafin V, Persano L, Moserle L, Esposito G, Ghisi M, Curtarello M, Bonanno L, Masiero M, Ribatti D, Stürzl M, Naschberger E, Croner RS, Jubb AM, Harris AL, Koeppen H, et al. Notch3 signalling promotes tumour growth in colorectal cancer. The Journal of Pathology. 224: 448-60. PMID 21598247 DOI: 10.1002/path.2895 |
0.661 |
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2011 |
Yan M, Jene N, Byrne D, Millar EK, O'Toole SA, McNeil CM, Bates GJ, Harris AL, Banham AH, Sutherland RL, Fox SB. Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers. Breast Cancer Research : Bcr. 13: R47. PMID 21521526 DOI: 10.1186/bcr2869 |
0.524 |
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2011 |
Ong CC, Jubb AM, Haverty PM, Zhou W, Tran V, Truong T, Turley H, O'Brien T, Vucic D, Harris AL, Belvin M, Friedman LS, Blackwood EM, Koeppen H, Hoeflich KP. Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 7177-82. PMID 21482786 DOI: 10.1073/Pnas.1103350108 |
0.767 |
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2011 |
Bridges E, Oon CE, Harris A. Notch regulation of tumor angiogenesis. Future Oncology (London, England). 7: 569-88. PMID 21463145 DOI: 10.2217/fon.11.20 |
0.695 |
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2011 |
Gee HE, Buffa FM, Camps C, Ramachandran A, Leek R, Taylor M, Patil M, Sheldon H, Betts G, Homer J, West C, Ragoussis J, Harris AL. The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis. British Journal of Cancer. 104: 1168-77. PMID 21407217 DOI: 10.1038/sj.bjc.6606076 |
0.699 |
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2011 |
Shaida N, Chan P, Turley H, Jones CM, Kanga S, Ritchie RW, Malone PR, Harris AL, Fox SB. Nuclear localization of factor inhibitor hypoxia-inducible factor in prostate cancer is associated with poor prognosis. The Journal of Urology. 185: 1513-8. PMID 21334674 DOI: 10.1016/j.juro.2010.12.001 |
0.678 |
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2011 |
Ghazoui Z, Buffa FM, Dunbier AK, Anderson H, Dexter T, Detre S, Salter J, Smith IE, Harris AL, Dowsett M. Close and stable relationship between proliferation and a hypoxia metagene in aromatase inhibitor-treated ER-positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3005-12. PMID 21325071 DOI: 10.1158/1078-0432.CCR-10-1704 |
0.34 |
|
2011 |
Murri-Plesko MT, Hulikova A, Oosterwijk E, Scott AM, Zortea A, Harris AL, Ritter G, Old L, Bauer S, Swietach P, Renner C. Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX. European Journal of Pharmacology. 657: 173-83. PMID 21315712 DOI: 10.1016/j.ejphar.2011.01.063 |
0.619 |
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2011 |
Fox SB, Generali D, Berruti A, Brizzi MP, Campo L, Bonardi S, Bersiga A, Allevi G, Milani M, Aguggini S, Mele T, Dogliotti L, Bottini A, Harris AL. The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen. Breast Cancer Research : Bcr. 13: R16. PMID 21291529 DOI: 10.1186/bcr2825 |
0.811 |
|
2011 |
Jubb AM, Miller KD, Rugo HS, Harris AL, Chen D, Reimann JD, Cobleigh MA, Schmidt M, Langmuir VK, Hillan KJ, Chen DS, Koeppen H. Impact of exploratory biomarkers on the treatment effect of bevacizumab in metastatic breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 372-81. PMID 21224365 DOI: 10.1158/1078-0432.Ccr-10-1791 |
0.675 |
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2011 |
Blick C, McCormick R, Ramachandran A, Cranston D, Catto J, Harris A. 495 THE HYPOXIC REGULATION OF FGFR3 IN NON MUSCLE INVASIVE BLADDER CANCER European Urology Supplements. 10: 167. DOI: 10.1016/S1569-9056(11)60486-7 |
0.653 |
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2010 |
Gijsen M, King P, Perera T, Parker PJ, Harris AL, Larijani B, Kong A. HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer. Plos Biology. 8: e1000563. PMID 21203579 DOI: 10.1371/journal.pbio.1000563 |
0.609 |
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2010 |
Lord S, Harris AL. Angiogenesis - still a worthwhile target for breast cancer therapy? Breast Cancer Research : Bcr. 12: S19. PMID 21172081 DOI: 10.1186/bcr2748 |
0.668 |
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2010 |
Jubb AM, Harris AL. Biomarkers to predict the clinical efficacy of bevacizumab in cancer. The Lancet. Oncology. 11: 1172-83. PMID 21126687 DOI: 10.1016/S1470-2045(10)70232-1 |
0.651 |
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2010 |
Giatromanolaki A, Koukourakis MI, Harris AL, Polychronidis A, Gatter KC, Sivridis E. Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas. Journal of Clinical Pathology. 63: 867-72. PMID 20876316 DOI: 10.1136/jcp.2010.079525 |
0.487 |
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2010 |
Chen L, Zeng X, Wang J, Briggs SS, O'Neill E, Li J, Leek R, Kerr DJ, Harris AL, Cai S. Roles of tetrahydrobiopterin in promoting tumor angiogenesis. The American Journal of Pathology. 177: 2671-80. PMID 20847284 DOI: 10.2353/ajpath.2010.100025 |
0.767 |
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2010 |
Yang J, Jubb AM, Pike L, Buffa FM, Turley H, Baban D, Leek R, Gatter KC, Ragoussis J, Harris AL. The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth. Cancer Research. 70: 6456-66. PMID 20682797 DOI: 10.1158/0008-5472.CAN-10-0413 |
0.822 |
|
2010 |
Mele T, Generali D, Fox S, Brizzi MP, Bersiga A, Milani M, Allevi G, Bonardi S, Aguggini S, Volante M, Dogliotti L, Bottini A, Harris A, Berruti A. Anti-angiogenic effect of tamoxifen combined with epirubicin in breast cancer patients. Breast Cancer Research and Treatment. 123: 795-804. PMID 20680681 DOI: 10.1007/s10549-010-1063-0 |
0.805 |
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2010 |
Biswas S, Troy H, Leek R, Chung YL, Li JL, Raval RR, Turley H, Gatter K, Pezzella F, Griffiths JR, Stubbs M, Harris AL. Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts. Journal of Oncology. 2010: 757908. PMID 20652061 DOI: 10.1155/2010/757908 |
0.81 |
|
2010 |
da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V, Germain MA, Reynolds AR, Jones DT, Watson AR, Jones JL, Harris A, Hart IR, et al. Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF. The American Journal of Pathology. 177: 1534-48. PMID 20639457 DOI: 10.2353/Ajpath.2010.100043 |
0.611 |
|
2010 |
Li JL, Jubb AM, Harris AL. Targeting DLL4 in tumors shows preclinical activity but potentially significant toxicity. Future Oncology (London, England). 6: 1099-103. PMID 20624122 DOI: 10.2217/fon.10.62 |
0.77 |
|
2010 |
Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CE, Leek R, Edelmann M, Kessler B, Sainson RC, Sargent I, Li JL, Harris AL. New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood. 116: 2385-94. PMID 20558614 DOI: 10.1182/blood-2009-08-239228 |
0.803 |
|
2010 |
McCormick R, Buffa FM, Ragoussis J, Harris AL. The role of hypoxia regulated microRNAs in cancer. Current Topics in Microbiology and Immunology. 345: 47-70. PMID 20549470 DOI: 10.1007/82_2010_76 |
0.735 |
|
2010 |
Rzymski T, Milani M, Pike L, Buffa F, Mellor HR, Winchester L, Pires I, Hammond E, Ragoussis I, Harris AL. Regulation of autophagy by ATF4 in response to severe hypoxia. Oncogene. 29: 4424-35. PMID 20514020 DOI: 10.1038/onc.2010.191 |
0.801 |
|
2010 |
Gossage L, Zaitoun A, Fareed KR, Turley H, Aloysius M, Lobo DN, Harris AL, Madhusudan S. Expression of key hypoxia sensing prolyl-hydroxylases PHD1, -2 and -3 in pancreaticobiliary cancer. Histopathology. 56: 908-20. PMID 20497244 DOI: 10.1111/j.1365-2559.2010.03566.x |
0.589 |
|
2010 |
Liu D, Hu J, Agorreta J, Cesario A, Zhang Y, Harris AL, Gatter K, Pezzella F. Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases. Cancer Letters. 296: 194-205. PMID 20471161 DOI: 10.1016/j.canlet.2010.04.017 |
0.574 |
|
2010 |
Thurlow JK, Peña Murillo CL, Hunter KD, Buffa FM, Patiar S, Betts G, West CM, Harris AL, Parkinson EK, Harrison PR, Ozanne BW, Partridge M, Kalna G. Spectral clustering of microarray data elucidates the roles of microenvironment remodeling and immune responses in survival of head and neck squamous cell carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 2881-8. PMID 20458058 DOI: 10.1200/Jco.2009.24.8724 |
0.754 |
|
2010 |
Grzmil M, Rzymski T, Milani M, Harris AL, Capper RG, Saunders NJ, Salhan A, Ragoussis J, Norbury CJ. An oncogenic role of eIF3e/INT6 in human breast cancer. Oncogene. 29: 4080-9. PMID 20453879 DOI: 10.1038/Onc.2010.152 |
0.832 |
|
2010 |
Favaro E, Ramachandran A, McCormick R, Gee H, Blancher C, Crosby M, Devlin C, Blick C, Buffa F, Li JL, Vojnovic B, Pires das Neves R, Glazer P, Iborra F, Ivan M, ... ... Harris AL, et al. MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. Plos One. 5: e10345. PMID 20436681 DOI: 10.1371/Journal.Pone.0010345 |
0.794 |
|
2010 |
Sivridis E, Koukourakis MI, Zois CE, Ledaki I, Ferguson DJ, Harris AL, Gatter KC, Giatromanolaki A. LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas. The American Journal of Pathology. 176: 2477-89. PMID 20382705 DOI: 10.2353/ajpath.2010.090049 |
0.815 |
|
2010 |
Azam F, Mehta S, Harris AL. Mechanisms of resistance to antiangiogenesis therapy. European Journal of Cancer (Oxford, England : 1990). 46: 1323-32. PMID 20236818 DOI: 10.1016/j.ejca.2010.02.020 |
0.822 |
|
2010 |
Gee HE, Camps C, Buffa FM, Patiar S, Winter SC, Betts G, Homer J, Corbridge R, Cox G, West CM, Ragoussis J, Harris AL. hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer. Cancer. 116: 2148-58. PMID 20187102 DOI: 10.1002/cncr.25009 |
0.786 |
|
2010 |
Jubb AM, Soilleux EJ, Turley H, Steers G, Parker A, Low I, Blades J, Li JL, Allen P, Leek R, Noguera-Troise I, Gatter KC, Thurston G, Harris AL. Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer. The American Journal of Pathology. 176: 2019-28. PMID 20167860 DOI: 10.2353/ajpath.2010.090908 |
0.824 |
|
2010 |
Pires IM, Bencokova Z, Milani M, Folkes LK, Li JL, Stratford MR, Harris AL, Hammond EM. Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability. Cancer Research. 70: 925-35. PMID 20103649 DOI: 10.1158/0008-5472.CAN-09-2715 |
0.751 |
|
2010 |
Mellor HR, Rouschop KM, Wigfield SM, Wouters BG, Harris AL. Synchronised phosphorylation of BNIP3, Bcl-2 and Bcl-xL in response to microtubule-active drugs is JNK-independent and requires a mitotic kinase. Biochemical Pharmacology. 79: 1562-72. PMID 20100468 DOI: 10.1016/j.bcp.2010.01.019 |
0.787 |
|
2010 |
Buffa FM, Harris AL, West CM, Miller CJ. Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene. British Journal of Cancer. 102: 428-35. PMID 20087356 DOI: 10.1038/sj.bjc.6605450 |
0.318 |
|
2010 |
Bonelli MA, Fumarola C, Alfieri RR, La Monica S, Cavazzoni A, Galetti M, Gatti R, Belletti S, Harris AL, Fox SB, Evans DB, Dowsett M, Martin LA, Bottini A, Generali D, et al. Synergistic activity of letrozole and sorafenib on breast cancer cells. Breast Cancer Research and Treatment. 124: 79-88. PMID 20054642 DOI: 10.1007/s10549-009-0714-5 |
0.657 |
|
2010 |
Charlesworth PJ, Kilbey N, Taylor M, Leek R, Cranston D, Turner G, Crew J, Harris A, Protheroe A. Automated uro-oncology data collection: the Cancer Research Uro-Oncology Database. Bju International. 105: 1663-6. PMID 19930178 DOI: 10.1111/j.1464-410X.2009.09058.x |
0.786 |
|
2010 |
Jubb AM, Buffa FM, Harris AL. Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis. Journal of Cellular and Molecular Medicine. 14: 18-29. PMID 19840191 DOI: 10.1111/j.1582-4934.2009.00944.x |
0.686 |
|
2010 |
Gijsen M, King P, Perera T, Parker P, Larijani B, Harris A, Kong A. Upregulation of ADAM proteases and HER ligands through a feedback loop mediates acquired resistance to trastuzumab in HER2-amplified breast cancer Breast Cancer Research. 12. DOI: 10.1186/bcr2493 |
0.6 |
|
2010 |
Hoeflich K, Ong C, Jubb A, Haverty P, Truong T, Harris A, Belvin M, Friedman L, Blackwood E, Koeppen H. 343 Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of squamous NSCLC cells European Journal of Cancer Supplements. 8: 109. DOI: 10.1016/S1359-6349(10)72050-4 |
0.609 |
|
2010 |
Oon C, Li J, Sainson R, Sheldon H, Turley H, Leek R, Harris A. 360 Role of DLL4 and JAG1 in tumour angiogenesis European Journal of Cancer Supplements. 8: 92. DOI: 10.1016/S1359-6349(10)71161-7 |
0.793 |
|
2009 |
Patel NS, Muneer A, Blick C, Arya M, Harris AL. Targeting vascular endothelial growth factor in renal cell carcinoma. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 30: 292-9. PMID 19940550 DOI: 10.1159/000260241 |
0.777 |
|
2009 |
Koukourakis MI, Giatromanolaki A, Winter S, Leek R, Sivridis E, Harris AL. Lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy. Oncology. 77: 285-92. PMID 19923867 DOI: 10.1159/000259260 |
0.773 |
|
2009 |
Rzymski T, Milani M, Singleton DC, Harris AL. Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia. Cell Cycle (Georgetown, Tex.). 8: 3838-47. PMID 19887912 DOI: 10.4161/cc.8.23.10086 |
0.805 |
|
2009 |
Koukourakis MI, Giatromanolaki A, Sheldon H, Buffa FM, Kouklakis G, Ragoussis I, Sivridis E, Harris AL. Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: vasculature-independent radiosensitizing effect of bevacizumab. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 7069-76. PMID 19887481 DOI: 10.1158/1078-0432.CCR-09-0688 |
0.515 |
|
2009 |
Yang J, Ledaki I, Turley H, Gatter KC, Montero JC, Li JL, Harris AL. Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases. Annals of the New York Academy of Sciences. 1177: 185-97. PMID 19845621 DOI: 10.1111/j.1749-6632.2009.05027.x |
0.771 |
|
2009 |
Jubb AM, Turley H, Moeller HC, Steers G, Han C, Li JL, Leek R, Tan EY, Singh B, Mortensen NJ, Noguera-Troise I, Pezzella F, Gatter KC, Thurston G, Fox SB, ... Harris AL, et al. Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. British Journal of Cancer. 101: 1749-57. PMID 19844231 DOI: 10.1038/sj.bjc.6605368 |
0.835 |
|
2009 |
Turley H, Steers G, Li JL, Sainson R, Harris AL, Pezzella F, Gatter KC. Corrigendum. Histopathology. 55: 463-4. PMID 19817897 DOI: 10.1111/j.1365-2559.2009.03412.x |
0.777 |
|
2009 |
Mujcic H, Rzymski T, Rouschop KM, Koritzinsky M, Milani M, Harris AL, Wouters BG. Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 92: 450-9. PMID 19726095 DOI: 10.1016/j.radonc.2009.08.017 |
0.835 |
|
2009 |
Poon E, Harris AL, Ashcroft M. Targeting the hypoxia-inducible factor (HIF) pathway in cancer. Expert Reviews in Molecular Medicine. 11: e26. PMID 19709449 DOI: 10.1017/S1462399409001173 |
0.34 |
|
2009 |
Farquharson MJ, Al-Ebraheem A, Geraki K, Leek R, Jubb A, Harris AL. Zinc presence in invasive ductal carcinoma of the breast and its correlation with oestrogen receptor status. Physics in Medicine and Biology. 54: 4213-23. PMID 19521003 DOI: 10.1088/0031-9155/54/13/016 |
0.738 |
|
2009 |
Swietach P, Patiar S, Supuran CT, Harris AL, Vaughan-Jones RD. The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths. The Journal of Biological Chemistry. 284: 20299-310. PMID 19458084 DOI: 10.1074/jbc.M109.006478 |
0.778 |
|
2009 |
Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JM, Guenther T. Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. British Journal of Cancer. 100: 1666-73. PMID 19436307 DOI: 10.1038/sj.bjc.6605026 |
0.577 |
|
2009 |
Milani M, Rzymski T, Mellor HR, Pike L, Bottini A, Generali D, Harris AL. The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib. Cancer Research. 69: 4415-23. PMID 19417138 DOI: 10.1158/0008-5472.CAN-08-2839 |
0.819 |
|
2009 |
Martinez JC, Müller MM, Turley H, Steers G, Choteau L, Li JL, Sainson R, Harris AL, Pezzella F, Gatter KC. Nuclear and membrane expression of the angiogenesis regulator delta-like ligand 4 (DLL4) in normal and malignant human tissues. Histopathology. 54: 598-606. PMID 19413639 DOI: 10.1111/j.1365-2559.2009.03279.x |
0.809 |
|
2009 |
Ebbesen P, Pettersen EO, Gorr TA, Jobst G, Williams K, Kieninger J, Wenger RH, Pastorekova S, Dubois L, Lambin P, Wouters BG, Van Den Beucken T, Supuran CT, Poellinger L, Ratcliffe P, ... ... Harris AL, et al. Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies. Journal of Enzyme Inhibition and Medicinal Chemistry. 24: 1-39. PMID 19330638 DOI: 10.1080/14756360902784425 |
0.302 |
|
2009 |
Lowndes SA, Sheldon HV, Cai S, Taylor JM, Harris AL. Copper chelator ATN-224 inhibits endothelial function by multiple mechanisms. Microvascular Research. 77: 314-26. PMID 19323979 DOI: 10.1016/j.mvr.2009.01.003 |
0.781 |
|
2009 |
Li JL, Harris AL. Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implications. Frontiers in Bioscience (Landmark Edition). 14: 3094-110. PMID 19273260 DOI: 10.2741/3438 |
0.653 |
|
2009 |
Generali D, Bates G, Berruti A, Brizzi MP, Campo L, Bonardi S, Bersiga A, Allevi G, Milani M, Aguggini S, Dogliotti L, Banham AH, Harris AL, Bottini A, Fox SB. Immunomodulation of FOXP3+ regulatory T cells by the aromatase inhibitor letrozole in breast cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1046-51. PMID 19188178 DOI: 10.1158/1078-0432.CCR-08-1507 |
0.786 |
|
2009 |
Tan EY, Yan M, Campo L, Han C, Takano E, Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, O'Toole SA, McNeil CM, Crea P, Segara D, Sutherland RL, ... Harris AL, et al. The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy. British Journal of Cancer. 100: 405-11. PMID 19165203 DOI: 10.1038/sj.bjc.6604844 |
0.765 |
|
2009 |
Generali D, Buffa FM, Berruti A, Brizzi MP, Campo L, Bonardi S, Bersiga A, Allevi G, Milani M, Aguggini S, Papotti M, Dogliotti L, Bottini A, Harris AL, Fox SB. Phosphorylated ERalpha, HIF-1alpha, and MAPK signaling as predictors of primary endocrine treatment response and resistance in patients with breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 227-34. PMID 19064988 DOI: 10.1200/JCO.2007.13.7083 |
0.798 |
|
2009 |
Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JM, Guenther T. Assessment of microvessel density and carbonic anhydrase-9 (CA-9) expression in rectal cancer. Pathology, Research and Practice. 205: 1-9. PMID 19008051 DOI: 10.1016/j.prp.2008.08.008 |
0.56 |
|
2009 |
Rasheed S, Harris AL, Tekkis PP, Turley H, Silver A, McDonald PJ, Talbot IC, Glynne-Jones R, Northover JMA, Guenther T. Erratum: Hypoxia-inducible factor-1α and -2α are expressed in most rectal cancers but only hypoxia-inducible factor-1α is associated with prognosis British Journal of Cancer. 101: 742-742. DOI: 10.1038/sj.bjc.6605242 |
0.566 |
|
2009 |
Charlesworth P, Protheroe A, Turner G, Roberts I, Harris A, Cranston D. 240 24 YEARS OF RENAL CELL CARCINOMA NEPHRECTOMIES IN OXFORD, UK (1983-2007) European Urology Supplements. 8: 180. DOI: 10.1016/S1569-9056(09)60245-1 |
0.724 |
|
2009 |
Jensen H, Nordsmark M, Donskov F, Marcussen N, Turley H, Gatter K, Harris A, von der Maase H. 7103 Baseline and on-treatment expression of HIF-1a, HIF-2a and CAIX in patients with metastatic renal cell carcinoma European Journal of Cancer Supplements. 7: 423. DOI: 10.1016/S1359-6349(09)71436-3 |
0.529 |
|
2009 |
Swietach P, Patiar S, Villafuerte FC, Harris AL, Vaughan-Jones RD. Confocal Imaging Of Extracellular pH With Fluorescein Derivatives Biophysical Journal. 96: 298a. DOI: 10.1016/j.bpj.2008.12.1481 |
0.715 |
|
2008 |
Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Lactate dehydrogenase 5 expression in non-Hodgkin B-cell lymphomas is associated with hypoxia regulated proteins. Leukemia & Lymphoma. 49: 2181-6. PMID 19021062 DOI: 10.1080/10428190802450629 |
0.761 |
|
2008 |
Lowndes SA, Adams A, Timms A, Fisher N, Smythe J, Watt SM, Joel S, Donate F, Hayward C, Reich S, Middleton M, Mazar A, Harris AL. Phase I study of copper-binding agent ATN-224 in patients with advanced solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7526-34. PMID 19010871 DOI: 10.1158/1078-0432.CCR-08-0315 |
0.73 |
|
2008 |
Milani M, Harris AL. Targeting tumour hypoxia in breast cancer. European Journal of Cancer (Oxford, England : 1990). 44: 2766-73. PMID 18990559 DOI: 10.1016/j.ejca.2008.09.025 |
0.715 |
|
2008 |
Gee HE, Camps C, Buffa FM, Colella S, Sheldon H, Gleadle JM, Ragoussis J, Harris AL. MicroRNA-10b and breast cancer metastasis. Nature. 455: E8-9; author reply E. PMID 18948893 DOI: 10.1038/nature07362 |
0.713 |
|
2008 |
Kong A, Calleja V, Leboucher P, Harris A, Parker PJ, Larijani B. HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells. Plos One. 3: e2881. PMID 18682844 DOI: 10.1371/journal.pone.0002881 |
0.615 |
|
2008 |
Giatromanolaki A, Bates GJ, Koukourakis MI, Sivridis E, Gatter KC, Harris AL, Banham AH. The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer. Gynecologic Oncology. 110: 216-21. PMID 18533240 DOI: 10.1016/j.ygyno.2008.04.021 |
0.525 |
|
2008 |
Generali D, Dovio A, Tampellini M, Tucci M, Tedoldi S, Torta M, Bonardi S, Allevi G, Aguggini S, Milani M, Harris AL, Bottini A, Dogliotti L, Angeli A, Berruti A. Changes of bone turnover markers and serum PTH after night or morning administration of zoledronic acid in breast cancer patients with bone metastases. British Journal of Cancer. 98: 1753-8. PMID 18506177 DOI: 10.1038/sj.bjc.6604390 |
0.699 |
|
2008 |
Farquharson MJ, Al-Ebraheem A, Falkenberg G, Leek R, Harris AL, Bradley DA. The distribution of trace elements Ca, Fe, Cu and Zn and the determination of copper oxidation state in breast tumour tissue using muSRXRF and muXANES. Physics in Medicine and Biology. 53: 3023-37. PMID 18490810 DOI: 10.1088/0031-9155/53/11/018 |
0.555 |
|
2008 |
Swietach P, Wigfield S, Cobden P, Supuran CT, Harris AL, Vaughan-Jones RD. Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths. The Journal of Biological Chemistry. 283: 20473-83. PMID 18482982 DOI: 10.1074/jbc.M801330200 |
0.776 |
|
2008 |
Giatromanolaki A, Koukourakis MI, Pezzella F, Sivridis E, Turley H, Harris AL, Gatter KC. Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin's lymphomas and correlate with hypoxia inducible factor activation. Hematological Oncology. 26: 219-24. PMID 18461646 DOI: 10.1002/hon.861 |
0.772 |
|
2008 |
Smythe J, Fox A, Fisher N, Frith E, Harris AL, Watt SM. Measuring angiogenic cytokines, circulating endothelial cells, and endothelial progenitor cells in peripheral blood and cord blood: VEGF and CXCL12 correlate with the number of circulating endothelial progenitor cells in peripheral blood. Tissue Engineering. Part C, Methods. 14: 59-67. PMID 18454646 DOI: 10.1089/tec.2007.0251 |
0.801 |
|
2008 |
Generali D, Fox SB, Brizzi MP, Allevi G, Bonardi S, Aguggini S, Milani M, Bersiga A, Campo L, Dionisio R, Vergoni F, Giardini R, Dogliotti L, Bottini A, Harris AL, et al. Down-regulation of phosphatidylinositol 3'-kinase/AKT/molecular target of rapamycin metabolic pathway by primary letrozole-based therapy in human breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 2673-80. PMID 18451231 DOI: 10.1158/1078-0432.CCR-07-1046 |
0.793 |
|
2008 |
Swietach P, Wigfield S, Supuran CT, Harris AL, Vaughan-Jones RD. Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion. Bju International. 101: 22-4. PMID 18430118 DOI: 10.1111/j.1464-410X.2008.07644.x |
0.781 |
|
2008 |
Rzymski T, Paantjens A, Bod J, Harris AL. Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-kappaB and ATF4. Oncogene. 27: 4532-43. PMID 18408768 DOI: 10.1038/onc.2008.100 |
0.701 |
|
2008 |
Williams CK, Segarra M, Sierra Mde L, Sainson RC, Tosato G, Harris AL. Regulation of CXCR4 by the Notch ligand delta-like 4 in endothelial cells. Cancer Research. 68: 1889-95. PMID 18339870 DOI: 10.1158/0008-5472.CAN-07-2181 |
0.713 |
|
2008 |
Lawrie CH, Gal S, Dunlop HM, Pushkaran B, Liggins AP, Pulford K, Banham AH, Pezzella F, Boultwood J, Wainscoat JS, Hatton CS, Harris AL. Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. British Journal of Haematology. 141: 672-5. PMID 18318758 DOI: 10.1111/j.1365-2141.2008.07077.x |
0.526 |
|
2008 |
Sainson RC, Harris AL. Regulation of angiogenesis by homotypic and heterotypic notch signalling in endothelial cells and pericytes: from basic research to potential therapies. Angiogenesis. 11: 41-51. PMID 18256896 DOI: 10.1007/s10456-008-9098-0 |
0.7 |
|
2008 |
Jiang X, Tian F, Du Y, Copeland NG, Jenkins NA, Tessarollo L, Wu X, Pan H, Hu XZ, Xu K, Kenney H, Egan SE, Turley H, Harris AL, Marini AM, et al. BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1118-30. PMID 18234890 DOI: 10.1523/Jneurosci.2262-07.2008 |
0.514 |
|
2008 |
Giatromanolaki A, Koukourakis MI, Pezzella F, Turley H, Sivridis E, Bouros D, Bougioukas G, Harris AL, Gatter KC. Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway. Cancer Letters. 262: 87-93. PMID 18187257 DOI: 10.1016/j.canlet.2007.11.041 |
0.761 |
|
2008 |
Shaida N, Launchbury R, Boddy JL, Jones C, Campo L, Turley H, Kanga S, Banham AH, Malone PR, Harris AL, Fox SB. Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines. The Prostate. 68: 336-43. PMID 18163427 DOI: 10.1002/pros.20707 |
0.819 |
|
2008 |
Bates GJ, Fox SB, Han C, Launchbury R, Leek RD, Harris AL, Banham AH. Expression of the forkhead transcription factor FOXP1 is associated with that of estrogen receptor-beta in primary invasive breast carcinomas. Breast Cancer Research and Treatment. 111: 453-9. PMID 18026833 DOI: 10.1007/s10549-007-9812-4 |
0.712 |
|
2008 |
Harrington LS, Sainson RC, Williams CK, Taylor JM, Shi W, Li JL, Harris AL. Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells. Microvascular Research. 75: 144-54. PMID 17692341 DOI: 10.1016/j.mvr.2007.06.006 |
0.822 |
|
2008 |
Giatromanolaki A, Koukourakis MI, Gatter KC, Harris AL, Sivridis E. BNIP3 expression in endometrial cancer relates to active hypoxia inducible factor 1alpha pathway and prognosis. Journal of Clinical Pathology. 61: 217-20. PMID 17513511 DOI: 10.1136/jcp.2007.046680 |
0.58 |
|
2008 |
Ameri K, Harris AL. Activating transcription factor 4. The International Journal of Biochemistry & Cell Biology. 40: 14-21. PMID 17466566 DOI: 10.1016/j.biocel.2007.01.020 |
0.789 |
|
2008 |
Kong A, Calleja V, Leboucher P, Harris A, Parker P, Larijani B. Activation of alternative HER receptors mediates resistance to EGFR tyrosine kinase inhibitors in breast cancer cells European Journal of Cancer Supplements. 6: 9. DOI: 10.1016/S1359-6349(08)71210-2 |
0.593 |
|
2008 |
Harris AL, Generali DG. Inhibitors of tumor angiogenesis Cancer Drug Design and Discovery. 351-381. DOI: 10.1016/B978-012369448-5.50018-5 |
0.532 |
|
2008 |
Charlesworth PJS, Harris AL. Hypoxic regulation of angiogenesis by HIF-1 Angiogenesis: An Integrative Approach From Science to Medicine. 169-179. DOI: 10.1007/978-0-387-71518-6_15 |
0.768 |
|
2007 |
Fox SB, Generali DG, Harris AL. Breast tumour angiogenesis. Breast Cancer Research : Bcr. 9: 216. PMID 18190723 DOI: 10.1186/bcr1796 |
0.632 |
|
2007 |
Tan EY, Campo L, Han C, Turley H, Pezzella F, Gatter KC, Harris AL, Fox SB. Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer. Breast Cancer Research : Bcr. 9: R89. PMID 18096060 DOI: 10.1186/bcr1838 |
0.777 |
|
2007 |
Li JL, Sainson RC, Shi W, Leek R, Harrington LS, Preusser M, Biswas S, Turley H, Heikamp E, Hainfellner JA, Harris AL. Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo. Cancer Research. 67: 11244-53. PMID 18056450 DOI: 10.1158/0008-5472.CAN-07-0969 |
0.812 |
|
2007 |
Kato T, Steers G, Campo L, Roberts H, Leek RD, Turley H, Kimura T, Kameoka S, Nishikawa T, Kobayashi M, Harris AL, Gatter KC, Pezzella F. Prognostic significance of microvessel density and other variables in Japanese and British patients with primary invasive breast cancer. British Journal of Cancer. 97: 1277-86. PMID 17923874 DOI: 10.1038/sj.bjc.6604015 |
0.77 |
|
2007 |
Sainson RC, Harris AL. Anti-Dll4 therapy: can we block tumour growth by increasing angiogenesis? Trends in Molecular Medicine. 13: 389-95. PMID 17822956 DOI: 10.1016/j.molmed.2007.07.002 |
0.705 |
|
2007 |
Mellor HR, Harris AL. The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer. Cancer Metastasis Reviews. 26: 553-66. PMID 17805942 DOI: 10.1007/s10555-007-9080-0 |
0.727 |
|
2007 |
Ord JJ, Agrawal S, Thamboo TP, Roberts I, Campo L, Turley H, Han C, Fawcett DW, Kulkarni RP, Cranston D, Harris AL. An investigation into the prognostic significance of necrosis and hypoxia in high grade and invasive bladder cancer. The Journal of Urology. 178: 677-82. PMID 17574616 DOI: 10.1016/j.juro.2007.03.112 |
0.81 |
|
2007 |
Li JL, Harris AL. The potential of new tumor endothelium-specific markers for the development of antivascular therapy. Cancer Cell. 11: 478-81. PMID 17560330 DOI: 10.1016/j.ccr.2007.05.004 |
0.657 |
|
2007 |
Trivella M, Pezzella F, Pastorino U, Harris AL, Altman DG. Microvessel density as a prognostic factor in non-small-cell lung carcinoma: a meta-analysis of individual patient data. The Lancet. Oncology. 8: 488-99. PMID 17513172 DOI: 10.1016/S1470-2045(07)70145-6 |
0.523 |
|
2007 |
Knowles HJ, Harris AL. Macrophages and the hypoxic tumour microenvironment. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4298-314. PMID 17485376 DOI: 10.2741/2389 |
0.635 |
|
2007 |
Banham AH, Boddy J, Launchbury R, Han C, Turley H, Malone PR, Harris AL, Fox SB. Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia. The Prostate. 67: 1091-8. PMID 17477366 DOI: 10.1002/pros.20583 |
0.821 |
|
2007 |
Rzymski T, Harris AL. The unfolded protein response and integrated stress response to anoxia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 2537-40. PMID 17473181 DOI: 10.1158/1078-0432.CCR-06-2126 |
0.703 |
|
2007 |
Swietach P, Vaughan-Jones RD, Harris AL. Regulation of tumor pH and the role of carbonic anhydrase 9. Cancer Metastasis Reviews. 26: 299-310. PMID 17415526 DOI: 10.1007/s10555-007-9064-0 |
0.622 |
|
2007 |
Winter SC, Buffa FM, Silva P, Miller C, Valentine HR, Turley H, Shah KA, Cox GJ, Corbridge RJ, Homer JJ, Musgrove B, Slevin N, Sloan P, Price P, West CM, ... Harris AL, et al. Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Research. 67: 3441-9. PMID 17409455 DOI: 10.1158/0008-5472.CAN-06-3322 |
0.743 |
|
2007 |
Fox SB, Launchbury R, Bates GJ, Han C, Shaida N, Malone PR, Harris AL, Banham AH. The number of regulatory T cells in prostate cancer is associated with the androgen receptor and hypoxia-inducible factor (HIF)-2alpha but not HIF-1alpha. The Prostate. 67: 623-9. PMID 17328069 DOI: 10.1002/pros.20538 |
0.435 |
|
2007 |
Sung FL, Hui EP, Tao Q, Li H, Tsui NB, Lo YM, Ma BB, To KF, Harris AL, Chan AT. Genome-wide expression analysis using microarray identified complex signaling pathways modulated by hypoxia in nasopharyngeal carcinoma. Cancer Letters. 253: 74-88. PMID 17320280 DOI: 10.1016/J.Canlet.2007.01.012 |
0.301 |
|
2007 |
Generali D, Fox SB, Berruti A, Moore JW, Brizzi MP, Patel N, Allevi G, Bonardi S, Aguggini S, Bersiga A, Campo L, Dogliotti L, Bottini A, Harris AL. Regulation of hepatocyte growth factor activator inhibitor 2 by hypoxia in breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 550-8. PMID 17255277 DOI: 10.1158/1078-0432.CCR-06-1266 |
0.769 |
|
2007 |
Tan EY, Campo L, Han C, Turley H, Pezzella F, Gatter KC, Harris AL, Fox SB. BNIP3 as a progression marker in primary human breast cancer; opposing functions in in situ versus invasive cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 467-74. PMID 17255267 DOI: 10.1158/1078-0432.CCR-06-1466 |
0.779 |
|
2007 |
Generali D, Leek R, Fox SB, Moore JW, Taylor C, Chambers P, Harris AL. EGFR mutations in exons 18-21 in sporadic breast cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 18: 203-5. PMID 17220285 DOI: 10.1093/annonc/mdl322 |
0.723 |
|
2007 |
Generali D, Berruti A, Brizzi MP, Campo L, Bonardi S, Wigfield S, Bersiga A, Allevi G, Milani M, Aguggini S, Gandolfi V, Dogliotti L, Bottini A, Harris AL, Fox SB. Hypoxia-inducible factor-1alpha expression predicts a poor response to primary chemoendocrine therapy and disease-free survival in primary human breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4562-8. PMID 16899602 DOI: 10.1158/1078-0432.CCR-05-2690 |
0.823 |
|
2007 |
Generali DG, Berruti A, Fox SB, Brizzi M, Bonardi S, Milani M, Bersiga A, Dionisio R, Dogliotti L, Bottini A, Harris AL. Down-regulation of HIF-1α expression by letrozole in ER+ve breast cancer patients Journal of Clinical Oncology. 25: 510-510. DOI: 10.1200/JCO.2007.25.18_SUPPL.510 |
0.775 |
|
2007 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL, Trarbach T, Folprecht G, Shi MM, Meinhardt G. Intratumoral lactate dehydrogenase 5 (LDH5) protein expression is associated with expression of angiogenesis markers and hypoxia in patients with colorectal cancer (CRC) Journal of Clinical Oncology. 25: 4107-4107. DOI: 10.1200/jco.2007.25.18_suppl.4107 |
0.523 |
|
2007 |
Sainson RCA, Li J, Harrington L, Shi W, Heikamp E, Leek R, Harris AL. In vivo assessment of Delta like‐4 function in tumour development The Faseb Journal. 21. DOI: 10.1096/fasebj.21.5.a16 |
0.771 |
|
2007 |
Koukourakis M, Giatromanolaki A, Sivridis E, Gatter K, Harris A, Shi M, Trarbach T, Folprecht G, Meinhardt G. 327 POSTER Expression of intratumoral lactate dehydrogenase 5 (LDH5) and expression of biomarkers for angiogenesis and hypoxia are linked in patients with colorectal cancer (CRC) European Journal of Cancer Supplements. 5: 64-65. DOI: 10.1016/S1359-6349(07)70345-2 |
0.511 |
|
2007 |
Van der Auwera I, Cao Y, Tille JC, Pepper MS, Jackson DG, Fox SB, Harris AL, Dirix LY, Vermeulen PB. First International Consensus on the Methodology of Lymphangiogenesis Quantification in Solid Human Tumors Cheminform. 38. DOI: 10.1002/CHIN.200725276 |
0.386 |
|
2006 |
Patiar S, Harris AL. Role of hypoxia-inducible factor-1alpha as a cancer therapy target. Endocrine-Related Cancer. 13: S61-75. PMID 17259560 DOI: 10.1677/erc.1.01290 |
0.803 |
|
2006 |
Bates GJ, Fox SB, Han C, Leek RD, Garcia JF, Harris AL, Banham AH. Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 5373-80. PMID 17135638 DOI: 10.1200/JCO.2006.05.9584 |
0.703 |
|
2006 |
Van der Auwera I, Cao Y, Tille JC, Pepper MS, Jackson DG, Fox SB, Harris AL, Dirix LY, Vermeulen PB. First international consensus on the methodology of lymphangiogenesis quantification in solid human tumours. British Journal of Cancer. 95: 1611-25. PMID 17117184 DOI: 10.1038/Sj.Bjc.6603445 |
0.446 |
|
2006 |
Farquharson MJ, Geraki K, Falkenberg G, Leek R, Harris A. The localisation and micro-mapping of copper and other trace elements in breast tumours using a synchrotron micro-XRF system. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 65: 183-8. PMID 17052909 DOI: 10.1016/J.APRADISO.2006.08.013 |
0.59 |
|
2006 |
Jones DT, Pugh CW, Wigfield S, Stevens MF, Harris AL. Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor-alpha expression but decrease functional transcriptional activity, DNA binding, and degradation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5384-94. PMID 17000671 DOI: 10.1158/1078-0432.CCR-05-2380 |
0.802 |
|
2006 |
Jones DT, Harris AL. Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding. Molecular Cancer Therapeutics. 5: 2193-202. PMID 16985052 DOI: 10.1158/1535-7163.MCT-05-0443 |
0.626 |
|
2006 |
Generali D, Fox SB, Berruti A, Brizzi MP, Campo L, Bonardi S, Wigfield SM, Bruzzi P, Bersiga A, Allevi G, Milani M, Aguggini S, Dogliotti L, Bottini A, Harris AL. Role of carbonic anhydrase IX expression in prediction of the efficacy and outcome of primary epirubicin/tamoxifen therapy for breast cancer. Endocrine-Related Cancer. 13: 921-30. PMID 16954440 DOI: 10.1677/erc.1.01216 |
0.814 |
|
2006 |
Shi W, Harris AL. Notch signaling in breast cancer and tumor angiogenesis: Cross-talk and therapeutic potentials Journal of Mammary Gland Biology and Neoplasia. 11: 41-52. PMID 16947085 DOI: 10.1007/s10911-006-9011-7 |
0.5 |
|
2006 |
Desmedt C, Ouriaghli FE, Durbecq V, Soree A, Colozza MA, Azambuja E, Paesmans M, Larsimont D, Buyse M, Harris A, Piccart M, Martiat P, Sotiriou C. Impact of cyclins E, neutrophil elastase and proteinase 3 expression levels on clinical outcome in primary breast cancer patients. International Journal of Cancer. 119: 2539-45. PMID 16929516 DOI: 10.1002/ijc.22149 |
0.31 |
|
2006 |
Lowndes SA, Harris AL. The role of copper in tumour angiogenesis. Journal of Mammary Gland Biology and Neoplasia. 10: 299-310. PMID 16924372 DOI: 10.1007/s10911-006-9003-7 |
0.761 |
|
2006 |
Patel NS, Dobbie MS, Rochester M, Steers G, Poulsom R, Le Monnier K, Cranston DW, Li JL, Harris AL. Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer Clinical Cancer Research. 12: 4836-4844. PMID 16914569 DOI: 10.1158/1078-0432.CCR-06-0285 |
0.769 |
|
2006 |
Giatromanolaki A, Sivridis E, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, Koukourakis MI. Hypoxia inducible factors 1alpha and 2alpha are associated with VEGF expression and angiogenesis in gallbladder carcinomas. Journal of Surgical Oncology. 94: 242-7. PMID 16900513 DOI: 10.1002/JSO.20443 |
0.495 |
|
2006 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL. Lactate dehydrogenase 5 expression in operable colorectal cancer: strong association with survival and activated vascular endothelial growth factor pathway--a report of the Tumour Angiogenesis Research Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 4301-8. PMID 16896001 DOI: 10.1200/JCO.2006.05.9501 |
0.554 |
|
2006 |
Adam PJ, Terrett JA, Steers G, Stockwin L, Loader JA, Fletcher GC, Lu LS, Leach BI, Mason S, Stamps AC, Boyd RS, Pezzella F, Gatter KC, Harris AL. CD70 (TNFSF7) is expressed at high prevalence in renal cell carcinomas and is rapidly internalised on antibody binding. British Journal of Cancer. 95: 298-306. PMID 16892042 DOI: 10.1038/sj.bjc.6603222 |
0.517 |
|
2006 |
Bottini A, Generali D, Brizzi MP, Fox SB, Bersiga A, Bonardi S, Allevi G, Aguggini S, Bodini G, Milani M, Dionisio R, Bernardi C, Montruccoli A, Bruzzi P, Harris AL, et al. Randomized phase II trial of letrozole and letrozole plus low-dose metronomic oral cyclophosphamide as primary systemic treatment in elderly breast cancer patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 3623-8. PMID 16877730 DOI: 10.1200/JCO.2005.04.5773 |
0.761 |
|
2006 |
Raida M, Weiss T, Leo C, Lenz D, Tarnok A, Ameri K, Harris AL, Höckel M, Niederwieser D. Circulating endothelial progenitor cells are inversely correlated with the median oxygen tension in the tumor tissue of patients with cervical cancer. Oncology Reports. 16: 597-601. PMID 16865261 DOI: 10.3892/OR.16.3.597 |
0.697 |
|
2006 |
Ameri K, Hammond EM, Culmsee C, Raida M, Katschinski DM, Wenger RH, Wagner E, Davis RJ, Hai T, Denko N, Harris AL. Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway. Oncogene. 26: 284-9. PMID 16847457 DOI: 10.1038/Sj.Onc.1209781 |
0.687 |
|
2006 |
Koukourakis MI, Papazoglou D, Giatromanolaki A, Panagopoulos I, Maltezos E, Harris AL, Gatter KC, Sivridis E. C2028T polymorphism in exon 12 and dinucleotide repeat polymorphism in intron 13 of the HIF-1alpha gene define HIF-1alpha protein expression in non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 53: 257-62. PMID 16837101 DOI: 10.1016/j.lungcan.2006.05.025 |
0.464 |
|
2006 |
Giatromanolaki A, Sivridis E, Gatter KC, Turley H, Harris AL, Koukourakis MI. Lactate dehydrogenase 5 (LDH-5) expression in endometrial cancer relates to the activated VEGF/VEGFR2(KDR) pathway and prognosis. Gynecologic Oncology. 103: 912-8. PMID 16837029 DOI: 10.1016/j.ygyno.2006.05.043 |
0.711 |
|
2006 |
Koukourakis MI, Giatromanolaki A, Polychronidis A, Simopoulos C, Gatter KC, Harris AL, Sivridis E. Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer. Cancer Science. 97: 582-8. PMID 16827797 DOI: 10.1111/j.1349-7006.2006.00220.x |
0.575 |
|
2006 |
Winter SC, Shah KA, Han C, Campo L, Turley H, Leek R, Corbridge RJ, Cox GJ, Harris AL. The relation between hypoxia-inducible factor (HIF)=1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer Cancer. 107: 757-766. PMID 16826581 DOI: 10.1002/cncr.21983 |
0.788 |
|
2006 |
Bacon AL, Fox S, Turley H, Harris AL. Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer. Oncogene. 26: 132-41. PMID 16799636 DOI: 10.1038/sj.onc.1209761 |
0.822 |
|
2006 |
Boddy JL, Gal S, Malone PR, Shaida N, Wainscoat JS, Harris AL. The role of cell-free DNA size distribution in the management of prostate cancer. Oncology Research. 16: 35-41. PMID 16783966 DOI: 10.3727/000000006783981297 |
0.721 |
|
2006 |
Giatromanolaki A, Koukourakis MI, Turley H, Sivridis E, Harris AL, Gatter KC. Phosphorylated KDR expression in endometrial cancer cells relates to HIF1alpha/VEGF pathway and unfavourable prognosis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 701-7. PMID 16557278 DOI: 10.1038/modpathol.3800579 |
0.729 |
|
2006 |
Charlesworth PJ, Harris AL. Mechanisms of disease: angiogenesis in urologic malignancies. Nature Clinical Practice. Urology. 3: 157-69. PMID 16528288 DOI: 10.1038/ncpuro0434 |
0.8 |
|
2006 |
Sainson RC, Harris AL. Hypoxia-regulated differentiation: let's step it up a Notch. Trends in Molecular Medicine. 12: 141-3. PMID 16513423 DOI: 10.1016/j.molmed.2006.02.001 |
0.726 |
|
2006 |
Kong A, Leboucher P, Leek R, Calleja V, Winter S, Harris A, Parker PJ, Larijani B. Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer. Cancer Research. 66: 2834-43. PMID 16510606 DOI: 10.1158/0008-5472.CAN-05-2994 |
0.799 |
|
2006 |
Jones DT, Trowbridge IS, Harris AL. Effects of transferrin receptor blockade on cancer cell proliferation and hypoxia-inducible factor function and their differential regulation by ascorbate. Cancer Research. 66: 2749-56. PMID 16510596 DOI: 10.1158/0008-5472.Can-05-3857 |
0.621 |
|
2006 |
Knowles HJ, Mole DR, Ratcliffe PJ, Harris AL. Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1. Cancer Research. 66: 2600-7. PMID 16510578 DOI: 10.1158/0008-5472.Can-05-2351 |
0.652 |
|
2006 |
Sotiriou C, Wirapati P, Loi S, Harris A, Fox S, Smeds J, Nordgren H, Farmer P, Praz V, Haibe-Kains B, Desmedt C, Larsimont D, Cardoso F, Peterse H, Nuyten D, et al. Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. Journal of the National Cancer Institute. 98: 262-72. PMID 16478745 DOI: 10.1093/jnci/djj052 |
0.49 |
|
2006 |
Blazquez C, Cook N, Micklem K, Harris AL, Gatter KC, Pezzella F. Phosphorylated KDR can be located in the nucleus of neoplastic cells. Cell Research. 16: 93-8. PMID 16467880 DOI: 10.1038/sj.cr.7310012 |
0.535 |
|
2006 |
Koukourakis MI, Giatromanolaki A, Harris AL, Sivridis E. Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma. Cancer Research. 66: 632-7. PMID 16423989 DOI: 10.1158/0008-5472.CAN-05-3260 |
0.515 |
|
2006 |
Koukourakis MI, Bentzen SM, Giatromanolaki A, Wilson GD, Daley FM, Saunders MI, Dische S, Sivridis E, Harris AL. Endogenous Markers of Two Separate Hypoxia Response Pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) Are Associated With Radiotherapy Failure in Head and Neck Cancer Patients Recruited in the CHART Randomized Trial Journal of Clinical Oncology. 24: 727-735. PMID 16418497 DOI: 10.1200/Jco.2005.02.7474 |
0.532 |
|
2006 |
Knowles HJ, te Poele RH, Te Poole R, Workman P, Harris AL. Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways. Biochemical Pharmacology. 71: 646-56. PMID 16386710 DOI: 10.1016/j.bcp.2005.11.019 |
0.659 |
|
2006 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL. Inclusion of vasculature-related variables in the Dukes staging system of colon cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8653-60. PMID 16361550 DOI: 10.1158/1078-0432.CCR-05-1464 |
0.461 |
|
2006 |
Smith CL, Mirza F, Pasquetto V, Tscharke DC, Palmowski MJ, Dunbar PR, Sette A, Harris AL, Cerundolo V. Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara. Journal of Immunology (Baltimore, Md. : 1950). 175: 8431-7. PMID 16339586 DOI: 10.4049/Jimmunol.175.12.8431 |
0.417 |
|
2006 |
Soilleux EJ, Turley H, Tian YM, Pugh CW, Gatter KC, Harris AL. Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues. Histopathology. 47: 602-10. PMID 16324198 DOI: 10.1111/j.1365-2559.2005.02280.x |
0.591 |
|
2006 |
Giatromanolaki A, Koukourakis MI, Sivridis E, Gatter KC, Harris AL, Banham AH. Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1alpha expression. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 19: 9-16. PMID 16258506 DOI: 10.1038/modpathol.3800494 |
0.533 |
|
2006 |
Williams CK, Li JL, Murga M, Harris AL, Tosato G. Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function. Blood. 107: 931-9. PMID 16219802 DOI: 10.1182/blood-2005-03-1000 |
0.663 |
|
2006 |
Lowndes SA, Adams A, Timms A, Middleton M, Hayward C, Reich SD, Mazar AP, Harris AL. Phase I study of ATN-224 in patients (pts) with advanced solid tumours Journal of Clinical Oncology. 24: 2065-2065. DOI: 10.1200/jco.2006.24.18_suppl.2065 |
0.732 |
|
2006 |
Doñate F, Lowndes S, Juarez J, Manuia M, Smith E, Liu N, Hayward C, Batuman O, Harris A, Mazar A. 132 POSTER Translation of in vitro markers of the anti-angiogenic and anti-tumor activity of the SOD1 inhibitor ATN-224 to clinical trials European Journal of Cancer Supplements. 4: 43. DOI: 10.1016/s1359-6349(06)70138-0 |
0.745 |
|
2006 |
Sainson RC, Harrington L, Shi W, Li JL, Williams C, Harris AL. Delta-Like 4 signaling regulates endothelial and surrounding cells' plasticity and cell fate determination during vascular development Vascular Pharmacology. 45: e43. DOI: 10.1016/j.vph.2006.08.185 |
0.783 |
|
2005 |
Ah-See ML, Burcombe RJ, Daley FM, Richman PI, Padhani AR, Bentzen SM, Fox SB, Harris AL, Makris A. Evaluation of tumour microvessel density & pericyte coverage index following neoadjuvant chemotherapy in primary breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 655. PMID 27946122 DOI: 10.1200/Jco.2005.23.16_Suppl.655 |
0.499 |
|
2005 |
Boddy JL, Fox SB, Han C, Campo L, Turley H, Kanga S, Malone PR, Harris AL. The androgen receptor is significantly associated with vascular endothelial growth factor and hypoxia sensing via hypoxia-inducible factors HIF-1a, HIF-2a, and the prolyl hydroxylases in human prostate cancer Clinical Cancer Research. 11: 7658-7663. PMID 16278385 DOI: 10.1158/1078-0432.CCR-05-0460 |
0.813 |
|
2005 |
Winter SC, Shah KA, Campo L, Turley H, Leek R, Corbridge RJ, Cox GJ, Harris AL. Relation of erythropoietin and erythropoietin receptor expression to hypoxia and anemia in head and neck squamous cell carcinoma Clinical Cancer Research. 11: 7614-7620. PMID 16278379 DOI: 10.1158/1078-0432.CCR-05-1097 |
0.795 |
|
2005 |
Van den Eynden GG, Van der Auwera I, Van Laere SJ, Colpaert CG, Turley H, Harris AL, van Dam P, Dirix LY, Vermeulen PB, Van Marck EA. Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer. British Journal of Cancer. 93: 1128-36. PMID 16251878 DOI: 10.1038/Sj.Bjc.6602828 |
0.608 |
|
2005 |
Kato T, Prevo R, Steers G, Roberts H, Leek RD, Kimura T, Kameoka S, Nishikawa T, Kobayashi M, Jackson DG, Harris AL, Gatter KC, Pezzella F. A quantitative analysis of lymphatic vessels in human breast cancer, based on LYVE-1 immunoreactivity. British Journal of Cancer. 93: 1168-74. PMID 16251871 DOI: 10.1038/sj.bjc.6602844 |
0.736 |
|
2005 |
Patel NS, Li JL, Generali D, Poulsom R, Cranston DW, Harris AL. Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function Cancer Research. 65: 8690-8697. PMID 16204037 DOI: 10.1158/0008-5472.CAN-05-1208 |
0.811 |
|
2005 |
Van Laere S, Van der Auwera I, Van den Eynden GG, Fox SB, Bianchi F, Harris AL, van Dam P, Van Marck EA, Vermeulen PB, Dirix LY. Distinct molecular signature of inflammatory breast cancer by cDNA microarray analysis. Breast Cancer Research and Treatment. 93: 237-46. PMID 16172796 DOI: 10.1007/S10549-005-5157-Z |
0.488 |
|
2005 |
Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Niederwieser D, Harris AL. Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis. Journal of Cancer Research and Clinical Oncology. 131: 741-50. PMID 16136355 DOI: 10.1007/s00432-005-0024-1 |
0.79 |
|
2005 |
Ord JJ, Streeter EH, Roberts IS, Cranston D, Harris AL. Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer. British Journal of Cancer. 93: 346-54. PMID 16052224 DOI: 10.1038/sj.bjc.6602666 |
0.773 |
|
2005 |
Li JL, Harris AL. Notch signaling from tumor cells: a new mechanism of angiogenesis. Cancer Cell. 8: 1-3. PMID 16023591 DOI: 10.1016/j.ccr.2005.06.013 |
0.645 |
|
2005 |
Clement JH, Raida M, Sänger J, Bicknell R, Liu J, Naumann A, Geyer A, Waldau A, Hortschansky P, Schmidt A, Höffken K, Wölft S, Harris AL. Bone morphogenetic protein 2 (BMP-2) induces in vitro invasion and in vivo hormone independent growth of breast carcinoma cells. International Journal of Oncology. 27: 401-7. PMID 16010421 |
0.704 |
|
2005 |
Raval RR, Lau KW, Tran MG, Sowter HM, Mandriota SJ, Li JL, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ. Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Molecular and Cellular Biology. 25: 5675-86. PMID 15964822 DOI: 10.1128/Mcb.25.13.5675-5686.2005 |
0.797 |
|
2005 |
Ord JJ, Streeter E, Jones A, Le Monnier K, Cranston D, Crew J, Joel SP, Rogers MA, Banks RE, Roberts IS, Harris AL. Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma. British Journal of Cancer. 92: 2140-7. PMID 15928663 DOI: 10.1038/sj.bjc.6602650 |
0.719 |
|
2005 |
Couvelard A, O'Toole D, Leek R, Turley H, Sauvanet A, Degott C, Ruszniewski P, Belghiti J, Harris AL, Gatter K, Pezzella F. Expression of hypoxia-inducible factors is correlated with the presence of a fibrotic focus and angiogenesis in pancreatic ductal adenocarcinomas. Histopathology. 46: 668-76. PMID 15910598 DOI: 10.1111/j.1365-2559.2005.02160.x |
0.789 |
|
2005 |
Leek RD, Stratford I, Harris AL. The role of hypoxia-inducible factor-1 in three-dimensional tumor growth, apoptosis, and regulation by the insulin-signaling pathway. Cancer Research. 65: 4147-52. PMID 15899805 DOI: 10.1158/0008-5472.CAN-04-2184 |
0.612 |
|
2005 |
Raida M, Clement JH, Ameri K, Han C, Leek RD, Harris AL. Expression of bone morphogenetic protein 2 in breast cancer cells inhibits hypoxic cell death. International Journal of Oncology. 26: 1465-70. PMID 15870857 |
0.831 |
|
2005 |
Brown NS, Streeter EH, Jones A, Harris AL, Bicknell R. Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder carcinoma. British Journal of Cancer. 92: 1696-701. PMID 15841086 DOI: 10.1038/sj.bjc.6602522 |
0.768 |
|
2005 |
Winter SC, Corbridge RJ, Cox GJ, Harris AL. Hypoxia and anaemia in head and neck squamous cell carcinoma - mechanisms of therapy failure and provision of new therapeutic targets. Clinical Otolaryngology : Official Journal of Ent-Uk ; Official Journal of Netherlands Society For Oto-Rhino-Laryngology & Cervico-Facial Surgery. 30: 99-104. PMID 15839859 DOI: 10.1111/j.1365-2273.2004.00946.x |
0.549 |
|
2005 |
Campo L, Turley H, Han C, Pezzella F, Gatter KC, Harris AL, Fox SB. Angiogenin is up-regulated in the nucleus and cytoplasm in human primary breast carcinoma and is associated with markers of hypoxia but not survival. The Journal of Pathology. 205: 585-91. PMID 15776477 DOI: 10.1002/path.1740 |
0.766 |
|
2005 |
Braybrooke JP, Slade A, Deplanque G, Harrop R, Madhusudan S, Forster MD, Gibson R, Makris A, Talbot DC, Steiner J, White L, Kan O, Naylor S, Carroll MW, Kingsman SM, ... Harris AL, et al. Phase I study of MetXia-P450 gene therapy and oral cyclophosphamide for patients with advanced breast cancer or melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 1512-20. PMID 15746054 DOI: 10.1158/1078-0432.CCR-04-0155 |
0.687 |
|
2005 |
Boddy JL, Gal S, Malone PR, Harris AL, Wainscoat JS. Prospective study of quantitation of plasma DNA levels in the diagnosis of malignant versus benign prostate disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 1394-9. PMID 15746038 DOI: 10.1158/1078-0432.CCR-04-1237 |
0.705 |
|
2005 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Gatter KC, Harris AL. Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma. Neoplasia (New York, N.Y.). 7: 1-6. PMID 15736311 DOI: 10.1593/neo.04373 |
0.539 |
|
2005 |
Pillai G, Cook N, Turley H, Leek RD, Blasquez C, Pezzella F, Harris AL, Gatter KC. The expression and cellular localization of phosphorylated VEGFR2 in lymphoma and non-neoplastic lymphadenopathy: an immunohistochemical study. Histopathology. 46: 209-16. PMID 15693894 DOI: 10.1111/j.1365-2559.2005.02081.x |
0.779 |
|
2005 |
Carroll VA, Nikitenko LL, Bicknell R, Harris AL. Antiangiogenic activity of a domain deletion mutant of tissue plasminogen activator containing kringle 2 Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 736-741. PMID 15692103 DOI: 10.1161/01.ATV.0000157980.15710.2b |
0.537 |
|
2005 |
Preusser M, Wolfsberger S, Haberler C, Breitschopf H, Czech T, Slavc I, Harris AL, Acker T, Budka H, Hainfellner JA. Vascularization and expression of hypoxia-related tissue factors in intracranial ependymoma and their impact on patient survival. Acta Neuropathologica. 109: 211-6. PMID 15614581 DOI: 10.1007/S00401-004-0938-8 |
0.3 |
|
2005 |
Hu J, Bianchi F, Ferguson M, Cesario A, Margaritora S, Granone P, Goldstraw P, Tetlow M, Ratcliffe C, Nicholson AG, Harris A, Gatter K, Pezzella F. Gene expression signature for angiogenic and nonangiogenic non-small-cell lung cancer. Oncogene. 24: 1212-9. PMID 15592519 DOI: 10.1038/sj.onc.1208242 |
0.57 |
|
2005 |
Giatromanolaki A, Koukourakis MI, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, Sivridis E. c-erbB-2 related aggressiveness in breast cancer is hypoxia inducible factor-1alpha dependent. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 7972-7. PMID 15585632 DOI: 10.1158/1078-0432.CCR-04-1068 |
0.526 |
|
2005 |
Fox SB, Harris AL. Histological quantitation of tumour angiogenesis. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 112: 413-30. PMID 15563306 DOI: 10.1111/j.1600-0463.2004.apm11207-0803.x |
0.465 |
|
2005 |
Couvelard A, O'Toole D, Turley H, Leek R, Sauvanet A, Degott C, Ruszniewski P, Belghiti J, Harris AL, Gatter K, Pezzella F. Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression. British Journal of Cancer. 92: 94-101. PMID 15558070 DOI: 10.1038/sj.bjc.6602245 |
0.805 |
|
2005 |
Bacon AL, Harris AL. Hypoxia-inducible factors and hypoxic cell death in tumour physiology. Annals of Medicine. 36: 530-9. PMID 15513303 DOI: 10.1080/07853890410018231 |
0.766 |
|
2005 |
Smith CL, Dunbar PR, Mirza F, Palmowski MJ, Shepherd D, Gilbert SC, Coulie P, Schneider J, Hoffman E, Hawkins R, Harris AL, Cerundolo V. Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence. International Journal of Cancer. 113: 259-66. PMID 15386406 DOI: 10.1002/Ijc.20569 |
0.424 |
|
2005 |
Giatromanolaki A, Koukourakis MI, Sowter HM, Sivridis E, Gibson S, Gatter KC, Harris AL. BNIP3 expression is linked with hypoxia-regulated protein expression and with poor prognosis in non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 5566-71. PMID 15328198 DOI: 10.1158/1078-0432.CCR-04-0076 |
0.802 |
|
2005 |
Boddy J, Fox S, Cheng H, Hurley H, Brown P, Malone P, Banham A, Harris A. 885Co-expression of the forkhead transcription factor, FOXPI with the androgen receptor in human prostate cancer, support its role as a potential co-regulator of this receptor European Urology Supplements. 4: 224. DOI: 10.1016/S1569-9056(05)80889-9 |
0.759 |
|
2005 |
Chong TW, Salio M, Hermans IF, Harris AL, Cerundolo V. Analysis of renal cell cancer tumour antigen carbonic anhydrase 9 specific cytotoxic T lymphocytes from a healthy HLA-A2 donor The Journal of Urology. 173: 96-96. DOI: 10.1016/S0022-5347(18)34605-6 |
0.551 |
|
2005 |
Boddy JL, Fox SB, Cheng H, Hurley H, Brown P, Malone PR, Harris AL. 237: Expression of the Androgen Receptor in Prostate Cancer is related to Vascular Endothelial Growth Factor and Hypoxia Inducible Factors 1: and 2 Journal of Urology. 173: 65-65. DOI: 10.1016/s0022-5347(18)34502-6 |
0.781 |
|
2005 |
Merajver S, Harris A. Introduction on Angiogenesis in Breast Cancer Journal of Mammary Gland Biology and Neoplasia. 10: 281-282. DOI: 10.1007/S10911-006-9000-X |
0.323 |
|
2004 |
Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Harris AL. Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 9531. PMID 28016826 DOI: 10.1200/jco.2004.22.14_suppl.9531 |
0.778 |
|
2004 |
Lowndes SA, Harris AL. Copper chelation as an antiangiogenic therapy Oncology Research. 14: 529-539. PMID 15666995 DOI: 10.3727/0965040042707952 |
0.75 |
|
2004 |
Silk JD, Hermans IF, Gileadi U, Chong TW, Shepherd D, Salio M, Mathew B, Schmidt RR, Lunt SJ, Williams KJ, Stratford IJ, Harris AL, Cerundolo V. Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy. The Journal of Clinical Investigation. 114: 1800-11. PMID 15599405 DOI: 10.1172/Jci200422046 |
0.789 |
|
2004 |
Van der Auwera I, Van Laere SJ, Van den Eynden GG, Benoy I, van Dam P, Colpaert CG, Fox SB, Turley H, Harris AL, Van Marck EA, Vermeulen PB, Dirix LY. Increased angiogenesis and lymphangiogenesis in inflammatory versus noninflammatory breast cancer by real-time reverse transcriptase-PCR gene expression quantification. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 7965-71. PMID 15585631 DOI: 10.1158/1078-0432.Ccr-04-0063 |
0.678 |
|
2004 |
Knies-Bamforth UE, Fox SB, Poulsom R, Evan GI, Harris AL. c-Myc interacts with hypoxia to induce angiogenesis in vivo by a vascular endothelial growth factor-dependent mechanism. Cancer Research. 64: 6563-70. PMID 15374969 DOI: 10.1158/0008-5472.CAN-03-3176 |
0.807 |
|
2004 |
Robertson N, Potter C, Harris AL. Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion. Cancer Research. 64: 6160-5. PMID 15342400 DOI: 10.1158/0008-5472.CAN-03-2224 |
0.797 |
|
2004 |
Fox SB, Bragança J, Turley H, Campo L, Han C, Gatter KC, Bhattacharya S, Harris AL. CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha. Cancer Research. 64: 6075-81. PMID 15342390 DOI: 10.1158/0008-5472.Can-04-0708 |
0.713 |
|
2004 |
Chakrabarti J, Turley H, Campo L, Han C, Harris AL, Gatter KC, Fox SB. The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. British Journal of Cancer. 91: 954-8. PMID 15328513 DOI: 10.1038/sj.bjc.6602059 |
0.713 |
|
2004 |
Appelhoff RJ, Tian YM, Raval RR, Turley H, Harris AL, Pugh CW, Ratcliffe PJ, Gleadle JM. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. The Journal of Biological Chemistry. 279: 38458-65. PMID 15247232 DOI: 10.1074/Jbc.M406026200 |
0.751 |
|
2004 |
Turley H, Wykoff CC, Troup S, Watson PH, Gatter KC, Harris AL. The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours. The Journal of Pathology. 203: 808-13. PMID 15221940 DOI: 10.1002/path.1585 |
0.711 |
|
2004 |
Knowles HJ, Tian YM, Mole DR, Harris AL. Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases. Circulation Research. 95: 162-9. PMID 15192023 DOI: 10.1161/01.RES.0000134924.89412.70 |
0.683 |
|
2004 |
Chung YL, Troy H, Judson IR, Leek R, Leach MO, Stubbs M, Harris AL, Griffiths JR. Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy Clinical Cancer Research. 10: 3863-3870. PMID 15173095 DOI: 10.1158/1078-0432.CCR-03-0237 |
0.583 |
|
2004 |
Fox SB, Brown P, Han C, Ashe S, Leek RD, Harris AL, Banham AH. Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor alpha and improved survival in primary human breast carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3521-7. PMID 15161711 DOI: 10.1158/1078-0432.CCR-03-0461 |
0.715 |
|
2004 |
Stephen RL, Gustafsson MC, Jarvis M, Tatoud R, Marshall BR, Knight D, Ehrenborg E, Harris AL, Wolf CR, Palmer CN. Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines. Cancer Research. 64: 3162-70. PMID 15126355 DOI: 10.1158/0008-5472.CAN-03-2760 |
0.306 |
|
2004 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Pastorek J, Karapantzos I, Gatter KC, Harris AL. Hypoxia-activated tumor pathways of angiogenesis and pH regulation independent of anemia in head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics. 59: 67-71. PMID 15093900 DOI: 10.1016/j.ijrobp.2003.10.016 |
0.515 |
|
2004 |
Knowles H, Leek R, Harris AL. Macrophage infiltration and angiogenesis in human malignancy. Novartis Foundation Symposium. 256: 189-200; discussion . PMID 15027491 |
0.776 |
|
2004 |
Fox SB, Turley H, Cheale M, Blázquez C, Roberts H, James N, Cook N, Harris A, Gatter K. Phosphorylated KDR is expressed in the neoplastic and stromal elements of human renal tumours and shuttles from cell membrane to nucleus. The Journal of Pathology. 202: 313-20. PMID 14991896 DOI: 10.1002/path.1520 |
0.666 |
|
2004 |
Madhusudan S, Deplanque G, Braybrooke JP, Cattell E, Taylor M, Price P, Tsaloumas MD, Moore N, Huson SM, Adams C, Frith P, Scigalla P, Harris AL. Antiangiogenic therapy for von Hippel-Lindau disease. Jama. 291: 943-4. PMID 14982909 DOI: 10.1001/JAMA.291.8.943 |
0.628 |
|
2004 |
Sowter HM, Ferguson M, Pym C, Watson P, Fox SB, Han C, Harris AL. Expression of the cell death genes BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade. The Journal of Pathology. 201: 573-80. PMID 14648660 DOI: 10.1002/path.1486 |
0.776 |
|
2004 |
Ameri K, Lewis CE, Raida M, Sowter H, Hai T, Harris AL. Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells. Blood. 103: 1876-82. PMID 14604972 DOI: 10.1182/Blood-2003-06-1859 |
0.831 |
|
2004 |
Giatromanolaki A, Sivridis E, Kouskoukis C, Gatter KC, Harris AL, Koukourakis MI. Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin. Melanoma Research. 13: 493-501. PMID 14512791 DOI: 10.1097/00008390-200310000-00008 |
0.55 |
|
2004 |
Stewart M, Turley H, Cook N, Pezzella F, Pillai G, Ogilvie D, Cartlidge S, Paterson D, Copley C, Kendrew J, Barnes C, Harris AL, Gatter KC. The angiogenic receptor KDR is widely distributed in human tissues and tumours and relocates intracellularly on phosphorylation. An immunohistochemical study. Histopathology. 43: 33-9. PMID 12823710 DOI: 10.1046/j.1365-2559.2003.01644.x |
0.7 |
|
2004 |
Raida M, Clement JH, Leek RD, Ameri K, Bicknell R, Harris AL. Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis Journal of Clinical Oncology. 22: 9531-9531. DOI: 10.1200/jco.2004.22.90140.9531 |
0.742 |
|
2004 |
Silk JD, Hermans IF, Gileadi U, Chong TW, Shepherd D, Salio M, Mathew B, Schmidt RR, Lunt SJ, Williams KJ, Stratford IJ, Harris AL, Cerundolo V. Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell–mediated immunotherapy Journal of Clinical Investigation. 114: 1800-1811. DOI: 10.1172/JCI200422046 |
0.515 |
|
2004 |
Boddy J, Gal S, Harris A, Wainscoat J, Malone P. 85 The diagnostic value of cell free DNA levels in prostate cancer and a reminder on the importance of sample selection European Urology Supplements. 3: 24. DOI: 10.1016/S1569-9056(04)90087-5 |
0.712 |
|
2004 |
Ord JJ, Cranston D, Harris AL, Campo L, Turley H, Allen P, Fox S, Davies DR. 773: C-KIT and CK7 Immunohistochemistry in the Differential Diagnosis of Renal Cell Carcinoma, A Study of 111 Cases Journal of Urology. 171: 205-205. DOI: 10.1016/s0022-5347(18)38022-4 |
0.6 |
|
2003 |
Hermans IF, Chong TW, Palmowski MJ, Harris AL, Cerundolo V. Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model. Cancer Research. 63: 8408-13. PMID 14679003 |
0.794 |
|
2003 |
Hermans IF, Silk JD, Gileadi U, Salio M, Mathew B, Ritter G, Schmidt R, Harris AL, Old L, Cerundolo V. NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 5140-7. PMID 14607913 DOI: 10.4049/Jimmunol.171.10.5140 |
0.559 |
|
2003 |
Braybrooke JP, Levitt NC, Joel S, Davis T, Madhusudan S, Turley H, Wilner S, Harris AL, Talbot DC. Pharmacokinetic study of cisplatin and infusional etoposide phosphate in advanced breast cancer with correlation of response to topoisomerase IIalpha expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4682-8. PMID 14581337 |
0.601 |
|
2003 |
Winters ZE, Leek RD, Bradburn MJ, Norbury CJ, Harris AL. Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis. Breast Cancer Research : Bcr. 5: R242-9. PMID 14580260 DOI: 10.1186/Bcr654 |
0.829 |
|
2003 |
Koukourakis MI, Giatromanolaki A, Chong W, Simopoulos C, Polychronidis A, Sivridis E, Harris AL. Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1 alpha. Cancer Chemotherapy and Pharmacology. 53: 8-14. PMID 14574457 DOI: 10.1007/s00280-003-0691-z |
0.495 |
|
2003 |
Colpaert CG, Vermeulen PB, Fox SB, Harris AL, Dirix LY, Van Marck EA. The presence of a fibrotic focus in invasive breast carcinoma correlates with the expression of carbonic anhydrase IX and is a marker of hypoxia and poor prognosis. Breast Cancer Research and Treatment. 81: 137-47. PMID 14572156 DOI: 10.1023/A:1025702330207 |
0.477 |
|
2003 |
Turner HE, Harris AL, Melmed S, Wass JA. Angiogenesis in endocrine tumors. Endocrine Reviews. 24: 600-32. PMID 14570746 DOI: 10.1210/er.2002-0008 |
0.583 |
|
2003 |
Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL. Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. Cancer Research. 63: 6130-4. PMID 14559790 |
0.819 |
|
2003 |
Tomes L, Emberley E, Niu Y, Troup S, Pastorek J, Strange K, Harris A, Watson PH. Necrosis and hypoxia in invasive breast carcinoma Breast Cancer Research and Treatment. 81: 61-69. PMID 14531498 DOI: 10.1023/A:1025476722493 |
0.33 |
|
2003 |
Kaklamanis L, Kakolyris S, Turley H, Koukourakis M, Biddolph S, Gatter KC, Harris AL. Neoplastic stroma and epithelium show up-regulation of platelet-derived endothelial cell growth factor/thymidine phosphorylase in colorectal carcinomas but not adenomas. Angiogenesis. 2: 49-55. PMID 14517375 DOI: 10.1023/A:1009002426554 |
0.614 |
|
2003 |
Adam PJ, Berry J, Loader JA, Tyson KL, Craggs G, Smith P, De Belin J, Steers G, Pezzella F, Sachsenmeir KF, Stamps AC, Herath A, Sim E, O'Hare MJ, Harris AL, et al. Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro. Molecular Cancer Research : McR. 1: 826-35. PMID 14517345 |
0.611 |
|
2003 |
Koukourakis MI, Giatromanolaki A, Brekken RA, Sivridis E, Gatter KC, Harris AL, Sage EH. Enhanced expression of SPARC/osteonectin in the tumor-associated stroma of non-small cell lung cancer is correlated with markers of hypoxia/acidity and with poor prognosis of patients. Cancer Research. 63: 5376-80. PMID 14500371 |
0.563 |
|
2003 |
Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, Jazaeri A, Martiat P, Fox SB, Harris AL, Liu ET. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proceedings of the National Academy of Sciences of the United States of America. 100: 10393-8. PMID 12917485 DOI: 10.1073/Pnas.1732912100 |
0.462 |
|
2003 |
Giatromanolaki A, Sivridis E, Maltezos E, Athanassou N, Papazoglou D, Gatter KC, Harris AL, Koukourakis MI. Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis. Arthritis Research & Therapy. 5: R193-201. PMID 12823854 DOI: 10.1186/ar756 |
0.495 |
|
2003 |
Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, Gatter KC, Harris AL. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. The Journal of Pathology. 200: 222-8. PMID 12754744 DOI: 10.1002/path.1330 |
0.764 |
|
2003 |
Williams CS, Leek RD, Robson AM, Banerji S, Prevo R, Harris AL, Jackson DG. Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer. The Journal of Pathology. 200: 195-206. PMID 12754740 DOI: 10.1002/path.1343 |
0.797 |
|
2003 |
Kuenen BC, Tabernero J, Baselga J, Cavalli F, Pfanner E, Conte PF, Seeber S, Madhusudan S, Deplanque G, Huisman H, Scigalla P, Hoekman K, Harris AL. Efficacy and toxicity of the angiogenesis inhibitor SU5416 as a single agent in patients with advanced renal cell carcinoma, melanoma, and soft tissue sarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1648-55. PMID 12738717 |
0.697 |
|
2003 |
Knowles HJ, Raval RR, Harris AL, Ratcliffe PJ. Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells. Cancer Research. 63: 1764-8. PMID 12702559 |
0.804 |
|
2003 |
Watson PH, Chia SK, Wykoff CC, Han C, Leek RD, Sly WS, Gatter KC, Ratcliffe P, Harris AL. Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma. British Journal of Cancer. 88: 1065-70. PMID 12671706 DOI: 10.1038/Sj.Bjc.6600796 |
0.635 |
|
2003 |
Colpaert CG, Vermeulen PB, Benoy I, Soubry A, van Roy F, van Beest P, Goovaerts G, Dirix LY, van Dam P, Fox SB, Harris AL, van Marck EA. Inflammatory breast cancer shows angiogenesis with high endothelial proliferation rate and strong E-cadherin expression. British Journal of Cancer. 88: 718-25. PMID 12618881 DOI: 10.1038/sj.bjc.6600807 |
0.533 |
|
2003 |
Giatromanolaki A, Sivridis E, Maltezos E, Papazoglou D, Simopoulos C, Gatter KC, Harris AL, Koukourakis MI. Hypoxia inducible factor 1alpha and 2alpha overexpression in inflammatory bowel disease. Journal of Clinical Pathology. 56: 209-13. PMID 12610101 DOI: 10.1136/jcp.56.3.209 |
0.473 |
|
2003 |
Swinson DE, Jones JL, Richardson D, Wykoff C, Turley H, Pastorek J, Taub N, Harris AL, O'Byrne KJ. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 473-82. PMID 12560438 DOI: 10.1200/JCO.2003.11.132 |
0.692 |
|
2003 |
Giatromanolaki A, Sivridis E, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, Koukourakis MI. Differential assessment of angiogenic activity and of vascular survival ability (VSA) in breast cancer. Clinical & Experimental Metastasis. 19: 673-9. PMID 12553372 DOI: 10.1023/A:1021354028685 |
0.559 |
|
2003 |
Propper DJ, Chao D, Braybrooke JP, Bahl P, Thavasu P, Balkwill F, Turley H, Dobbs N, Gatter K, Talbot DC, Harris AL, Ganesan TS. Low-dose IFN-gamma induces tumor MHC expression in metastatic malignant melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 84-92. PMID 12538455 |
0.565 |
|
2003 |
Leek RD, Harris AL. Tumor-associated macrophages in breast cancer. Journal of Mammary Gland Biology and Neoplasia. 7: 177-89. PMID 12463738 DOI: 10.1023/A:1020304003704 |
0.643 |
|
2003 |
Giatromanolaki A, Sivridis E, Simopoulos C, Polychronidis A, Gatter KC, Harris AL, Koukourakis MI. Thymidine phosphorylase expression in gallbladder adenocarcinomas. International Journal of Surgical Pathology. 10: 181-8. PMID 12232571 DOI: 10.1177/106689690201000303 |
0.531 |
|
2003 |
Boddy J, Gal S, Malone P, Harris A, Wainscoat J. Investigating the relationship between plasma DNA levels and prostate cancer European Urology Supplements. 2: 84. DOI: 10.1016/S1569-9056(03)90445-3 |
0.701 |
|
2003 |
Giatromanolaki A, Sivridis E, Kouskoukis C, Gatter K, Harris A, Koukourakis M. 839 Hypoxia-inducible factors 1a and 2a in skin malignant melanomas European Journal of Cancer Supplements. 1: S252-S253. DOI: 10.1016/S1359-6349(03)90865-2 |
0.394 |
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2003 |
Harris AL. Angiogenesis as a new target for cancer control European Journal of Cancer, Supplement. 1: 1-12. DOI: 10.1016/S1359-6349(03)00007-7 |
0.337 |
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2002 |
Adeyinka A, Emberley E, Niu Y, Snell L, Murphy LC, Sowter H, Wykoff CC, Harris AL, Watson PH. Analysis of gene expression in ductal carcinoma in situ of the breast Clinical Cancer Research. 8: 3788-3795. PMID 12473591 |
0.793 |
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2002 |
Chong TW, Horwitz LD, Moore JW, Sowter HM, Harris AL. A mycobacterial iron chelator, desferri-exochelin, induces hypoxia-inducible factors 1 and 2, NIP3, and vascular endothelial growth factor in cancer cell lines. Cancer Research. 62: 6924-7. PMID 12460908 |
0.83 |
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2002 |
Currie MJ, Gunningham SP, Turner K, Han C, Scott PA, Robinson BA, Chong W, Harris AL, Fox SB. Expression of the angiopoietins and their receptor Tie2 in human renal clear cell carcinomas; regulation by the von Hippel-Lindau gene and hypoxia. The Journal of Pathology. 198: 502-10. PMID 12434420 DOI: 10.1002/path.1228 |
0.81 |
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2002 |
Collingridge DR, Carroll VA, Glaser M, Aboagye EO, Osman S, Hutchinson OC, Barthel H, Luthra SK, Brady F, Bicknell R, Price P, Harris AL. The development of [(124)I]iodinated-VG76e: a novel tracer for imaging vascular endothelial growth factor in vivo using positron emission tomography. Cancer Research. 62: 5912-9. PMID 12384557 |
0.57 |
|
2002 |
Wilson KS, Roberts H, Leek R, Harris AL, Geradts J. Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. The American Journal of Pathology. 161: 1171-85. PMID 12368191 DOI: 10.1016/S0002-9440(10)64394-5 |
0.657 |
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2002 |
Goonewardene TI, Sowter HM, Harris AL. Hypoxia-induced pathways in breast cancer. Microscopy Research and Technique. 59: 41-8. PMID 12242695 DOI: 10.1002/jemt.10175 |
0.781 |
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2002 |
Sivridis E, Giatromanolaki A, Gatter KC, Harris AL, Koukourakis MI. Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma. Cancer. 95: 1055-63. PMID 12209691 DOI: 10.1002/cncr.10774 |
0.501 |
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2002 |
Hui EP, Chan AT, Pezzella F, Turley H, To KF, Poon TC, Zee B, Mo F, Teo PM, Huang DP, Gatter KC, Johnson PJ, Harris AL. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2595-604. PMID 12171890 |
0.71 |
|
2002 |
Vermeulen PB, Gasparini G, Fox SB, Colpaert C, Marson LP, Gion M, Beliën JA, de Waal RM, Van Marck E, Magnani E, Weidner N, Harris AL, Dirix LY. Second international consensus on the methodology and criteria of evaluation of angiogenesis quantification in solid human tumours. European Journal of Cancer (Oxford, England : 1990). 38: 1564-79. PMID 12142044 |
0.383 |
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2002 |
Koukourakis MI, Giatromanolaki A, Sivridis E, Simopoulos C, Turley H, Talks K, Gatter KC, Harris AL. Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics. 53: 1192-202. PMID 12128120 DOI: 10.1016/S0360-3016(02)02848-1 |
0.827 |
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2002 |
Mandriota SJ, Turner KJ, Davies DR, Murray PG, Morgan NV, Sowter HM, Wykoff CC, Maher ER, Harris AL, Ratcliffe PJ, Maxwell PH. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell. 1: 459-68. PMID 12124175 DOI: 10.1016/S1535-6108(02)00071-5 |
0.802 |
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2002 |
Streeter EH, Harris AL. Angiogenesis in bladder cancer--prognostic marker and target for future therapy. Surgical Oncology. 11: 85-100. PMID 12031871 DOI: 10.1016/S0960-7404(02)00013-0 |
0.758 |
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2002 |
Turner KJ, Moore JW, Jones A, Taylor CF, Cuthbert-Heavens D, Han C, Leek RD, Gatter KC, Maxwell PH, Ratcliffe PJ, Cranston D, Harris AL. Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation. Cancer Research. 62: 2957-61. PMID 12019178 |
0.789 |
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2002 |
Beasley NJ, Leek R, Alam M, Turley H, Cox GJ, Gatter K, Millard P, Fuggle S, Harris AL. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Research. 62: 2493-7. PMID 11980639 |
0.739 |
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2002 |
Sivridis E, Giatromanolaki A, Anastasiadis P, Georgiou L, Gatter KC, Harris AL, Bicknell R, Koukourakis MI. Angiogenic co-operation of VEGF and stromal cell TP in endometrial carcinomas. The Journal of Pathology. 196: 416-22. PMID 11920737 DOI: 10.1002/path.1060 |
0.545 |
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2002 |
Fox SB, Gasparini G, Harris AL. Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs. The Lancet. Oncology. 2: 278-89. PMID 11905783 DOI: 10.1016/S1470-2045(00)00323-5 |
0.496 |
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2002 |
Pezzella F, Harris AL, Gatter KC. Ways of escape: are all tumours angiogenic? Histopathology. 39: 551-3. PMID 11903570 DOI: 10.1046/j.1365-2559.2001.01027.x |
0.515 |
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2002 |
Harris AL. Hypoxia - A key regulatory factor in tumour growth Nature Reviews Cancer. 2: 38-47. PMID 11902584 |
0.312 |
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2002 |
Leek RD, Talks KL, Pezzella F, Turley H, Campo L, Brown NS, Bicknell R, Taylor M, Gatter KC, Harris AL. Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer. Cancer Research. 62: 1326-9. PMID 11888900 |
0.828 |
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2002 |
Beasley NJ, Prevo R, Banerji S, Leek RD, Moore J, van Trappen P, Cox G, Harris AL, Jackson DG. Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer. Cancer Research. 62: 1315-20. PMID 11888898 |
0.637 |
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2002 |
Jones A, Fujiyama C, Turner K, Cranston D, Williams K, Stratford I, Bicknell R, Harris AL. Role of thymidine phosphorylase in an in vitro model of human bladder cancer invasion. The Journal of Urology. 167: 1482-6. PMID 11832774 |
0.805 |
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2002 |
Griffiths JR, McSheehy PMJ, Robinson SP, Troy H, Chung YL, Leek RD, Williams KJ, Stratford IJ, Harris AL, Stubbs M. Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1β (HIF-1β): Evidence of an anabolic role for the HIF-1 pathway Cancer Research. 62: 688-695. PMID 11830521 |
0.618 |
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2002 |
Giatromanolaki A, Sivridis E, Brekken R, Thorpe PE, Anastasiadis P, Gatter KC, Harris AL, Koukourakis MI. The angiogenic "vascular endothelial growth factor/flk-1(KDR) receptor" pathway in patients with endometrial carcinoma: prognostic and therapeutic implications. Cancer. 92: 2569-77. PMID 11745191 DOI: 10.1002/1097-0142(20011115)92:10<2569::AID-CNCR1609>3.0.CO;2-3 |
0.512 |
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2002 |
Kelly CE, Leek RD, Byrne HM, Cox SM, Harris AL, Lewis CE. Modelling macrophage infiltration into avascular tumours Journal of Theoretical Medicine. 4: 21-38. DOI: 10.1080/10273660290015242 |
0.538 |
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2001 |
Winters ZE, Hunt NC, Bradburn MJ, Royds JA, Turley H, Harris AL, Norbury CJ. Subcellular localisation of cyclin B, Cdc2 and p21(WAF1/CIP1) in breast cancer. association with prognosis. European Journal of Cancer (Oxford, England : 1990). 37: 2405-12. PMID 11720835 DOI: 10.1016/S0959-8049(01)00327-6 |
0.595 |
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2001 |
O'Byrne KJ, Cox G, Swinson D, Richardson D, Edwards JG, Lolljee J, Andi A, Koukourakis MI, Giatromanolaki A, Gatter K, Harris AL, Waller D, Jones JL. Towards a biological staging model for operable non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 34: S83-9. PMID 11720747 DOI: 10.1016/S0169-5002(01)00352-X |
0.515 |
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2001 |
Knowles HJ, Harris AL. Hypoxia and tumorigenesis Breast Cancer Research. 3: 318-322. PMID 11597321 DOI: 10.1186/bcr314 |
0.677 |
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2001 |
Fox SB, Taylor M, Grøndahl-Hansen J, Kakolyris S, Gatter KC, Harris AL. Plasminogen activator inhibitor-1 as a measure of vascular remodelling in breast cancer. The Journal of Pathology. 195: 236-43. PMID 11592104 DOI: 10.1002/path.931 |
0.504 |
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2001 |
Chia SK, Wykoff CC, Watson PH, Han C, Leek RD, Pastorek J, Gatter KC, Ratcliffe P, Harris AL. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 3660-8. PMID 11504747 DOI: 10.1200/Jco.2001.19.16.3660 |
0.634 |
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2001 |
Giatromanolaki A, Koukourakis MI, Sivridis E, Thorpe PE, Brekken RA, Konstantinos S, Fountzilas G, Gatter KC, Harris AL. Tumor specific activation of the VEGF/KDR angiogenic pathway in a subset of locally advanced squamous cell head and neck carcinomas. Clinical & Experimental Metastasis. 18: 313-9. PMID 11448062 DOI: 10.1023/A:1011083121295 |
0.549 |
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2001 |
Giatromanolaki A, Sivridis E, Athanassou N, Zois E, Thorpe PE, Brekken RA, Gatter KC, Harris AL, Koukourakis IM, Koukourakis MI. The angiogenic pathway "vascular endothelial growth factor/flk-1(KDR)-receptor" in rheumatoid arthritis and osteoarthritis. The Journal of Pathology. 194: 101-8. PMID 11329148 DOI: 10.1002/path.842 |
0.483 |
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2001 |
Gunningham SP, Currie MJ, Han C, Robinson BA, Scott PA, Harris AL, Fox SB. VEGF-B expression in human primary breast cancers is associated with lymph node metastasis but not angiogenesis. The Journal of Pathology. 193: 325-32. PMID 11241411 DOI: 10.1002/path.814 |
0.507 |
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2000 |
Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. The American Journal of Pathology. 157: 411-21. PMID 10934146 DOI: 10.1016/S0002-9440(10)64554-3 |
0.779 |
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2000 |
Braybrooke JP, Propper DJ, O'Byrne KJ, Koukourakis MI, Patterson AV, Houlbrook S, Love SD, Varcoe S, Taylor M, Ganesan TS, Talbot DC, Harris AL. Induction of thymidine phosphorylase as a pharmacodynamic end-point in patients with advanced carcinoma treated with 5-fluorouracil, folinic acid and interferon alpha British Journal of Cancer. 83: 219-224. PMID 10901374 DOI: 10.1054/bjoc.2000.1230 |
0.436 |
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2000 |
Jones A, Fujiyama C, Turner K, Fuggle S, Cranston D, Turley H, Valtola R, Bicknell R, Harris AL. Angiogenesis and lymphangiogenesis in stage 1 germ cell tumours of the testis. Bju International. 86: 80-6. PMID 10886088 DOI: 10.1046/j.1464-410x.2000.00660.x |
0.556 |
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2000 |
Kakolyris S, Fox SB, Koukourakis M, Giatromanolaki A, Brown N, Leek RD, Taylor M, Leigh IM, Gatter KC, Harris AL. Relationship of vascular maturation in breast cancer blood vessels to vascular density and metastasis, assessed by expression of a novel basement membrane component, LH39. British Journal of Cancer. 82: 844-51. PMID 10732757 DOI: 10.1054/bjoc.1999.1010 |
0.517 |
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2000 |
Leek RD, Hunt NC, Landers RJ, Lewis CE, Royds JA, Harris AL. Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. The Journal of Pathology. 190: 430-6. PMID 10699991 DOI: 10.1002/(SICI)1096-9896(200003)190:4<430::AID-PATH538>3.0.CO;2-6 |
0.668 |
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2000 |
Sivridis E, Giatromanolaki A, Koukourakis MI, Bicknell R, Harris AL, Gatter KC. Thymidine phosphorylase expression in endometrial carcinomas. Clinical & Experimental Metastasis. 17: 445-50. PMID 10651312 DOI: 10.1023/A:1006603709248 |
0.553 |
|
2000 |
Fox SB, Gatter KC, Leek RD, Harris AL, Chew KL, Mayall BH, Moore DH. More about: Tumor angiogenesis as a prognostic assay for invasive ductal breast carcinoma. Journal of the National Cancer Institute. 92: 161-2. PMID 10639519 DOI: 10.1093/jnci/92.2.161 |
0.686 |
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2000 |
Crew JP, Fuggle S, Bicknell R, Cranston DW, de Benedetti A, Harris AL. Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression. British Journal of Cancer. 82: 161-6. PMID 10638984 DOI: 10.1054/bjoc.1999.0894 |
0.307 |
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1999 |
Koukourakis MI, Giatromanolaki A, O'Byrne KJ, Jiles C, Krammer B, Gatter KC, Harris AL. bcl-2 and c-erbB-2 proteins are involved in the regulation of VEGF and of thymidine phosphorylase angiogenic activity in non-small-cell lung cancer Clinical and Experimental Metastasis. 17: 545-554. PMID 10845553 DOI: 10.1023/A:1006780710148 |
0.535 |
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1999 |
Giatromanolaki A, Stathopoulos GP, Tsiompanou E, Tsiobanou E, Papadimitriou C, Georgoulias V, Gatter KC, Harris AL, Koukourakis MI. Combined role of tumor angiogenesis, bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma. Cancer. 86: 1421-30. PMID 10526268 DOI: 10.1002/(SICI)1097-0142(19991015)86:8<1421::AID-CNCR6>3.0.CO;2-X |
0.468 |
|
1999 |
O'Byrne KJ, Philip PA, Propper DJ, Braybrooke JP, Saunders MP, Bates NP, Taylor MA, Madigan D, Ganesan TS, Talbot DC, Harris AL. A phase II study of the modulation of 5-fluorouracil and folinic acid with high-dose infusional hydroxyurea in metastatic colorectal carcinoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 10: 981-3. PMID 10509162 DOI: 10.1023/A:1008330302535 |
0.458 |
|
1999 |
Smith K, Fox SB, Whitehouse R, Taylor M, Greenall M, Clarke J, Harris AL. Upregulation of basic fibroblast growth factor in breast carcinoma and its relationship to vascular density, oestrogen receptor, epidermal growth factor receptor and survival. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 10: 707-13. PMID 10442194 DOI: 10.1023/A:1008303614441 |
0.524 |
|
1999 |
Arapandoni-Dadioti P, Giatromanolaki A, Trihia H, Harris AL, Koukourakis MI. Angiogenesis in ductal breast carcinoma. Comparison of microvessel density between primary tumour and lymph node metastasis. Cancer Letters. 137: 145-50. PMID 10374835 DOI: 10.1016/S0304-3835(98)00343-7 |
0.447 |
|
1999 |
Turley H, Scott PA, Watts VM, Bicknell R, Harris AL, Gatter KC. Expression of VEGF in routinely fixed material using a new monoclonal antibody VG1. The Journal of Pathology. 186: 313-8. PMID 10211122 DOI: 10.1002/(SICI)1096-9896(1998110)186:3<313::AID-PATH188>3.0.CO;2-X |
0.58 |
|
1999 |
O'Byrne KJ, Dobbs N, Propper DJ, Braybrooke JP, Koukourakis MI, Mitchel K, Woodhull J, Talbot DC, Schally AV, Harris AL. Phase II study of RC-160 (vapreotide), an octapeptide analogue of somatostatin, in the treatment of metastatic breast cancer British Journal of Cancer. 79: 1413-1418. PMID 10188884 DOI: 10.1038/Sj.Bjc.6690226 |
0.493 |
|
1999 |
Patterson A, Harris AL. Molecular chemotherapy for breast cancer Drugs and Aging. 14: 75-90. PMID 10084362 DOI: 10.2165/00002512-199914020-00001 |
0.319 |
|
1999 |
Leek RD, Landers RJ, Harris AL, Lewis CE. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. British Journal of Cancer. 79: 991-5. PMID 10070902 DOI: 10.1038/sj.bjc.6690158 |
0.628 |
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1999 |
Ellis MJ, Jenkins S, Hanfelt J, Redington ME, Taylor M, Leek R, Siddle K, Harris A. Insulin-like growth factors in human breast cancer. Breast Cancer Research and Treatment. 52: 175-84. PMID 10066081 DOI: 10.1023/A:1006127621512 |
0.637 |
|
1999 |
Giatromanolaki A, Fountzilas G, Koukourakis MI, Arapandoni P, Theologi V, Kakolyris S, Georgoulias V, Harris AL, Gatter KC. Neo-angiogenesis in locally advanced squamous cell head and neck cancer correlates with thymidine phosphorylase expression and p53 nuclear oncoprotein accumulation. Clinical & Experimental Metastasis. 16: 665-72. PMID 9932613 DOI: 10.1023/A:1006554512338 |
0.526 |
|
1999 |
Guddo F, Giatromanolaki A, Koukourakis MI, Reina C, Vignola AM, Chlouverakis G, Hilkens J, Gatter KC, Harris AL, Bonsignore G. MUC1 (episialin) expression in non-small cell lung cancer is independent of EGFR and c-erbB-2 expression and correlates with poor survival in node positive patients. Journal of Clinical Pathology. 51: 667-71. PMID 9930070 DOI: 10.1136/jcp.51.9.667 |
0.505 |
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