Dick B. Janssen - Publications

Affiliations: 
University of Groningen, Groningen, Netherlands 

49/326 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Marjanovic A, Ramírez-Palacios CJ, Masman MF, Drenth J, Otzen M, Marrink SJ, Janssen DB. Thermostable D-amino acid decarboxylases derived from Thermotoga maritima diaminopimelate decarboxylase. Protein Engineering, Design & Selection : Peds. 34. PMID 34258615 DOI: 10.1093/protein/gzab016  0.32
2018 Li R, Wijma HJ, Song L, Cui Y, Otzen M, Tian Y, Du J, Li T, Niu D, Chen Y, Feng J, Han J, Chen H, Tao Y, Janssen DB, et al. Computational redesign of enzymes for regio- and enantioselective hydroamination. Nature Chemical Biology. PMID 29785057 DOI: 10.1038/s41589-018-0053-0  0.31
2016 Wu B, Wijma HJ, Song L, Rozeboom HJ, Poloni C, Tian Y, Arif MI, Nuijens T, Quaedflieg PJLM, Szymanski W, Feringa BL, Janssen DB. Versatile Peptide C-Terminal Functionalization via a Computationally Engineered Peptide Amidase Acs Catalysis. 6: 5405-5414. DOI: 10.1021/ACSCATAL.6B01062  0.572
2015 Otzen M, Crismaru CG, Postema CP, Wijma HJ, Heberling MM, Szymanski W, de Wildeman S, Janssen DB. Metabolism of β-valine via a CoA-dependent ammonia lyase pathway. Applied Microbiology and Biotechnology. 99: 8987-98. PMID 26004802 DOI: 10.1007/s00253-015-6551-z  0.613
2014 Floor RJ, Wijma HJ, Colpa DI, Ramos-Silva A, Jekel PA, Szyma?ski W, Feringa BL, Marrink SJ, Janssen DB. Computational library design for increasing haloalkane dehalogenase stability. Chembiochem : a European Journal of Chemical Biology. 15: 1660-72. PMID 24976371 DOI: 10.1002/cbic.201402128  0.317
2014 Wybenga GG, Szymanski W, Wu B, Feringa BL, Janssen DB, Dijkstra BW. Structural investigations into the stereochemistry and activity of a phenylalanine-2,3-aminomutase from Taxus chinensis. Biochemistry. 53: 3187-98. PMID 24786474 DOI: 10.1021/Bi500187A  0.66
2014 Arif MI, Toplak A, Szymanski W, Feringa BL, Nuijens T, Quaedflieg PJLM, Wu B, Janssen DB. One-step C-terminal deprotection and activation of peptides with peptide amidase from stenotrophomonas maltophilia in neat organic solvent Advanced Synthesis and Catalysis. 356: 2197-2202. DOI: 10.1002/adsc.201400109  0.582
2013 Raj H, Szymanski W, de Villiers J, Puthan Veetil V, Quax WJ, Shimamoto K, Janssen DB, Feringa BL, Poelarends GJ. Kinetic resolution and stereoselective synthesis of 3-substituted aspartic acids by using engineered methylaspartate ammonia lyases. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 11148-52. PMID 23852946 DOI: 10.1002/chem.201301832  0.664
2013 Heberling MM, Wu B, Bartsch S, Janssen DB. Priming ammonia lyases and aminomutases for industrial and therapeutic applications. Current Opinion in Chemical Biology. 17: 250-60. PMID 23557642 DOI: 10.1016/j.cbpa.2013.02.013  0.306
2013 Szyma?ski W, Wu B, Poloni C, Janssen DB, Feringa BL. Azobenzene photoswitches for Staudinger-Bertozzi ligation. Angewandte Chemie (International Ed. in English). 52: 2068-72. PMID 23307784 DOI: 10.1002/anie.201208596  0.322
2013 Crismaru CG, Wybenga GG, Szymanski W, Wijma HJ, Wu B, Bartsch S, de Wildeman S, Poelarends GJ, Feringa BL, Dijkstra BW, Janssen DB. Biochemical properties and crystal structure of a β-phenylalanine aminotransferase from Variovorax paradoxus. Applied and Environmental Microbiology. 79: 185-95. PMID 23087034 DOI: 10.1128/Aem.02525-12  0.656
2013 Schmidt E, Mandt C, Janssen DB, Pieper DH, Reineke W. Degradation of chloroaromatics: structure and catalytic activities of wild-type chlorocatechol 2,3-dioxygenases and modified ones. Environmental Microbiology. 15: 183-90. PMID 22816508 DOI: 10.1111/j.1462-2920.2012.02831.x  0.309
2012 Wybenga GG, Crismaru CG, Janssen DB, Dijkstra BW. Structural determinants of the β-selectivity of a bacterial aminotransferase. The Journal of Biological Chemistry. 287: 28495-502. PMID 22745123 DOI: 10.1074/Jbc.M112.375238  0.311
2012 Raj H, Szyma?ski W, de Villiers J, Rozeboom HJ, Veetil VP, Reis CR, de Villiers M, Dekker FJ, de Wildeman S, Quax WJ, Thunnissen AM, Feringa BL, Janssen DB, Poelarends GJ. Engineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acids. Nature Chemistry. 4: 478-84. PMID 22614383 DOI: 10.1038/nchem.1338  0.492
2012 Wu B, Szyma?ski W, Wybenga GG, Heberling MM, Bartsch S, de Wildeman S, Poelarends GJ, Feringa BL, Dijkstra BW, Janssen DB. Mechanism-inspired engineering of phenylalanine aminomutase for enhanced β-regioselective asymmetric amination of cinnamates. Angewandte Chemie (International Ed. in English). 51: 482-6. PMID 22113970 DOI: 10.1002/Anie.201106372  0.431
2012 Raj H, Puthan Veetil V, Szymanski W, Dekker FJ, Quax WJ, Feringa BL, Janssen DB, Poelarends GJ. Characterization of a thermostable methylaspartate ammonia lyase from Carboxydothermus hydrogenoformans. Applied Microbiology and Biotechnology. 94: 385-97. PMID 22005738 DOI: 10.1007/s00253-011-3615-6  0.642
2012 Westerbeek A, Van Leeuwen JGE, Szymański W, Feringa BL, Janssen DB. Haloalkane dehalogenase catalysed desymmetrisation and tandem kinetic resolution for the preparation of chiral haloalcohols Tetrahedron. 68: 7645-7650. DOI: 10.1016/j.tet.2012.06.059  0.394
2012 Wu B, Szymanski W, Crismaru CG, Feringa BL, Janssen DB. C-N lyases Catalyzing Addition of Ammonia, Amines, and Amides to C=C and C=O Bonds Enzyme Catalysis in Organic Synthesis, Third Edition. 2: 749-778. DOI: 10.1002/9783527639861.ch18  0.566
2011 Szyma?ski W, Westerbeek A, Janssen DB, Feringa BL. A simple enantioconvergent and chemoenzymatic synthesis of optically active α-substituted amides. Angewandte Chemie (International Ed. in English). 50: 10712-5. PMID 21922620 DOI: 10.1002/anie.201105164  0.382
2011 Wu B, Szyma?ski W, Heberling MM, Feringa BL, Janssen DB. Aminomutases: mechanistic diversity, biotechnological applications and future perspectives. Trends in Biotechnology. 29: 352-62. PMID 21477876 DOI: 10.1016/j.tibtech.2011.02.005  0.372
2011 Koetsier MJ, Jekel PA, Wijma HJ, Bovenberg RA, Janssen DB. Aminoacyl-coenzyme A synthesis catalyzed by a CoA ligase from Penicillium chrysogenum. Febs Letters. 585: 893-8. PMID 21334330 DOI: 10.1016/j.febslet.2011.02.018  0.347
2011 Westerbeek A, Szymański W, Feringa BL, Janssen DB. Dynamic kinetic resolution process employing haloalkane dehalogenase Acs Catalysis. 1: 1654-1660. DOI: 10.1021/cs2003565  0.311
2011 Westerbeek A, Szymański W, Wijma HJ, Marrink SJ, Feringa BL, Janssen DB. Kinetic resolution of α-bromoamides: Experimental and theoretical investigation of highly enantioselective reactions catalyzed by haloalkane dehalogenases Advanced Synthesis and Catalysis. 353: 931-944. DOI: 10.1002/adsc.201000726  0.418
2010 Wu B, Szyma?ski W, Wijma HJ, Crismaru CG, de Wildeman S, Poelarends GJ, Feringa BL, Janssen DB. Engineering of an enantioselective tyrosine aminomutase by mutation of a single active site residue in phenylalanine aminomutase. Chemical Communications (Cambridge, England). 46: 8157-9. PMID 20924508 DOI: 10.1039/c0cc02768e  0.431
2010 Weiner B, Szyma?ski W, Janssen DB, Minnaard AJ, Feringa BL. Recent advances in the catalytic asymmetric synthesis of β-amino acids Chemical Society Reviews. 39: 1656-1691. PMID 20419214 DOI: 10.1039/B919599H  0.482
2010 Verkuijl BJ, Szyma?ski W, Wu B, Minnaard AJ, Janssen DB, de Vries JG, Feringa BL. Enantiomerically pure beta-phenylalanine analogues from alpha-beta-phenylalanine mixtures in a single reactive extraction step. Chemical Communications (Cambridge, England). 46: 901-3. PMID 20107644 DOI: 10.1039/B921661H  0.39
2010 Campbell-Verduyn LS, Szyma?ski W, Postema CP, Dierckx RA, Elsinga PH, Janssen DB, Feringa BL. One pot 'click' reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition. Chemical Communications (Cambridge, England). 46: 898-900. PMID 20107643 DOI: 10.1039/B919434G  0.418
2010 Jerphagnon T, Haak R, Berthiol F, Gayet AJA, Ritleng V, Holuigue A, Pannetier N, Pfeffer M, Voelklin A, Lefort L, Verzijl G, Tarabiono C, Janssen DB, Minnaard AJ, Feringa BL, et al. Ruthenacycles and iridacycles as catalysts for asymmetric transfer hydrogenation and racemisation Topics in Catalysis. 53: 1002-1008. DOI: 10.1007/S11244-010-9569-6  0.391
2010 Weiner B, Szymanski W, Janssen DB, Minnaard AJ, Feringa BL. ChemInform Abstract: Recent Advances in the Catalytic Asymmetric Synthesis of β-Amino Acids Cheminform. 41: no-no. DOI: 10.1002/CHIN.201036240  0.632
2010 Campbell-Verduyn LS, Szymanski W, Postema CP, Dierckx RA, Elsinga PH, Janssen DB, Feringa BL. ChemInform Abstract: One-Pot “Click” Reactions: Tandem Enantioselective Biocatalytic Epoxide Ring Opening and [3 + 2] Azide Cycloaddition. Cheminform. 41: no-no. DOI: 10.1002/chin.201024029  0.616
2010 Verkuijl BJV, Szymanski W, Wu B, Minnaard AJ, Janssen DB, de Vries JG, Feringa BL. ChemInform Abstract: Enantiomerically Pure β-Phenylalanine Analogues from α-β-Phenylalanine Mixtures in a Single Reactive Extraction Step. Cheminform. 41: no-no. DOI: 10.1002/CHIN.201022182  0.599
2010 Szymanski W, Postema CP, Tarabiono C, Berthiol F, Campbell-Verduyn L, De Wildeman S, De Vries JG, Feringa BL, Janssen DB. Combining designer cells and click chemistry for a one-pot four-step preparation of enantiopure β-hydroxytriazoles Advanced Synthesis and Catalysis. 352: 2111-2115. DOI: 10.1002/Adsc.201000502  0.628
2010 Wu B, Szymański W, de Wildeman S, Poelarends G, Feringa B, Janssen D. Efficient Tandem Biocatalytic Process for the Kinetic Resolution of Aromatic β-Amino Acids Advanced Synthesis & Catalysis. 352: 1409-1412. DOI: 10.1002/ADSC.201000035  0.658
2009 Szymanski W, Wu B, Weiner B, de Wildeman S, Feringa BL, Janssen DB. Phenylalanine aminomutase-catalyzed addition of ammonia to substituted cinnamic acids: a route to enantiopure alpha- and beta-amino acids. The Journal of Organic Chemistry. 74: 9152-7. PMID 19894731 DOI: 10.1021/Jo901833Y  0.665
2009 Wu B, Szymanski W, Wietzes P, de Wildeman S, Poelarends GJ, Feringa BL, Janssen DB. Enzymatic synthesis of enantiopure alpha- and beta-amino acids by phenylalanine aminomutase-catalysed amination of cinnamic acid derivatives. Chembiochem : a European Journal of Chemical Biology. 10: 338-44. PMID 19123196 DOI: 10.1002/cbic.200800568  0.677
2009 Koetsier MJ, Jekel PA, van den Berg MA, Bovenberg RA, Janssen DB. Characterization of a phenylacetate-CoA ligase from Penicillium chrysogenum. The Biochemical Journal. 417: 467-76. PMID 18834333 DOI: 10.1042/BJ20081257  0.304
2008 Weiner B, Poelarends GJ, Janssen DB, Feringa BL. Biocatalytic enantioselective synthesis of N-substituted aspartic acids by aspartate ammonia lyase. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10094-100. PMID 18844200 DOI: 10.1002/Chem.200801407  0.513
2008 Haak RM, Berthiol F, Jerphagnon T, Gayet AJ, Tarabiono C, Postema CP, Ritleng V, Pfeffer M, Janssen DB, Minnaard AJ, Feringa BL, de Vries JG. Dynamic kinetic resolution of racemic beta-haloalcohols: direct access to enantioenriched epoxides. Journal of the American Chemical Society. 130: 13508-9. PMID 18800793 DOI: 10.1021/Ja805128X  0.382
2008 Elenkov MM, Tang L, Meetsma A, Hauer B, Janssen DB. Formation of enantiopure 5-substituted oxazolidinones through enzyme-catalysed kinetic resolution of epoxides. Organic Letters. 10: 2417-20. PMID 18491860 DOI: 10.1021/ol800698t  0.328
2008 van Loo B, Permentier HP, Kingma J, Baldascini H, Janssen DB. Inactivation of epoxide hydrolase by catalysis-induced formation of isoaspartate. Febs Letters. 582: 1581-6. PMID 18406355 DOI: 10.1016/j.febslet.2008.04.001  0.31
2007 Haak RM, Tarabiono C, Janssen DB, Minnaard AJ, de Vries JG, Feringa BL. Synthesis of enantiopure chloroalcohols by enzymatic kinetic resolution. Organic & Biomolecular Chemistry. 5: 318-23. PMID 17205176 DOI: 10.1039/B613937J  0.426
2007 Haak RM, Tarabiono C, Janssen DB, Minnaard AJ, de Vries JG, Feringa BL. Synthesis of Enantiopure Chloroalcohols by Enzymatic Kinetic Resolution. Cheminform. 38. DOI: 10.1002/CHIN.200720030  0.422
2005 Panella L, Broos J, Jin J, Fraaije MW, Janssen DB, Jeronimus-Stratingh M, Feringa BL, Minnaard AJ, de Vries JG. Merging homogeneous catalysis with biocatalysis; papain as hydrogenation catalyst. Chemical Communications (Cambridge, England). 5656-8. PMID 16292380 DOI: 10.1039/B512138H  0.307
2004 de Vries EJ, Janssen DB. Biocatalytic conversion of epoxides. Current Opinion in Biotechnology. 14: 414-20. PMID 12943851 DOI: 10.1016/S0958-1669(03)00102-2  0.356
2003 Alkema WB, de Vries E, Floris R, Janssen DB. Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics. European Journal of Biochemistry. 270: 3675-83. PMID 12950251 DOI: 10.1046/J.1432-1033.2003.03728.X  0.327
2002 Polderman-Tijmes JJ, Jekel PA, Jeronimus-Stratingh CM, Bruins AP, Van Der Laan JM, Sonke T, Janssen DB. Identification of the catalytic residues of alpha-amino acid ester hydrolase from Acetobacter turbidans by labeling and site-directed mutagenesis. The Journal of Biological Chemistry. 277: 28474-82. PMID 12011065 DOI: 10.1074/jbc.M204143200  0.32
2001 Poelarends GJ, Saunier R, Janssen DB. trans-3-Chloroacrylic acid dehalogenase from Pseudomonas pavonaceae 170 shares structural and mechanistic similarities with 4-oxalocrotonate tautomerase. Journal of Bacteriology. 183: 4269-77. PMID 11418568 DOI: 10.1128/JB.183.14.4269-4277.2001  0.31
1997 Rink R, Fennema M, Smids M, Dehmel U, Janssen DB. Primary structure and catalytic mechanism of the epoxide hydrolase from Agrobacterium radiobacter AD1. The Journal of Biological Chemistry. 272: 14650-7. PMID 9169427 DOI: 10.1074/JBC.272.23.14650  0.329
1994 Pries F, Kingma J, Pentenga M, van Pouderoyen G, Jeronimus-Stratingh CM, Bruins AP, Janssen DB. Site-directed mutagenesis and oxygen isotope incorporation studies of the nucleophilic aspartate of haloalkane dehalogenase. Biochemistry. 33: 1242-7. PMID 8110757 DOI: 10.1021/BI00171A026  0.307
Low-probability matches (unlikely to be authored by this person)
2013 Bartsch S, Wybenga GG, Jansen M, Heberling MM, Wu B, Dijkstra BW, Janssen DB. Redesign of a phenylalanine aminomutase into a phenylalanine ammonia lyase Chemcatchem. 5: 1797-1802. DOI: 10.1002/Cctc.201200871  0.3
1997 Krooshof GH, Kwant EM, Damborský J, Koca J, Janssen DB. Repositioning the catalytic triad aspartic acid of haloalkane dehalogenase: effects on stability, kinetics, and structure. Biochemistry. 36: 9571-80. PMID 9236003 DOI: 10.1021/BI971014T  0.297
1992 Jacobs MH, Van den Wijngaard AJ, Pentenga M, Janssen DB. Characterization of the epoxide hydrolase from an epichlorohydrin-degrading Pseudomonas sp. European Journal of Biochemistry. 202: 1217-22. PMID 1662605 DOI: 10.1111/J.1432-1033.1991.TB16493.X  0.293
1992 van Hylckama Vlieg JE, Janssen DB. Bacterial degradation of 3-chloroacrylic acid and the characterization of cis- and trans-specific dehalogenases. Biodegradation. 2: 139-50. PMID 1368960 DOI: 10.1007/BF00124488  0.29
2003 Kamerbeek NM, Olsthoorn AJ, Fraaije MW, Janssen DB. Substrate specificity and enantioselectivity of 4-hydroxyacetophenone monooxygenase. Applied and Environmental Microbiology. 69: 419-26. PMID 12514023 DOI: 10.1128/AEM.69.1.419-426.2003  0.288
2018 Lanfranchi E, Trajković M, Barta K, de Vries JG, Janssen DB. Exploring the selective demethylation of aryl-methyl ethers by a Pseudomonas Rieske monooxygenase. Chembiochem : a European Journal of Chemical Biology. PMID 30362644 DOI: 10.1002/Cbic.201800594  0.288
2009 Raj H, Weiner B, Veetil VP, Reis CR, Quax WJ, Janssen DB, Feringa BL, Poelarends GJ. Alteration of the diastereoselectivity of 3-methylaspartate ammonia lyase by using structure-based mutagenesis. Chembiochem : a European Journal of Chemical Biology. 10: 2236-45. PMID 19670200 DOI: 10.1002/Cbic.200900311  0.288
2019 Palacio CM, Rozeboom HJ, Lanfranchi E, Meng Q, Otzen M, Janssen DB. Biochemical properties of a Pseudomonas aminotransferase involved in caprolactam metabolism. The Febs Journal. PMID 31162815 DOI: 10.1111/febs.14950  0.282
2015 Toplak A, Nuijens T, Quaedflieg PJ, Wu B, Janssen DB. Peptide synthesis in neat organic solvents with novel thermostable proteases. Enzyme and Microbial Technology. 73: 20-8. PMID 26002500 DOI: 10.1016/j.enzmictec.2015.03.003  0.281
2002 Polderman-Tijmes JJ, Jekel PA, de Vries EJ, van Merode AE, Floris R, van der Laan JM, Sonke T, Janssen DB. Cloning, sequence analysis, and expression in Escherichia coli of the gene encoding an alpha-amino acid ester hydrolase from Acetobacter turbidans. Applied and Environmental Microbiology. 68: 211-8. PMID 11772629 DOI: 10.1128/AEM.68.1.211-218.2002  0.281
2004 Alkema WB, Hensgens CM, Snijder HJ, Keizer E, Dijkstra BW, Janssen DB. Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase. Protein Engineering, Design & Selection : Peds. 17: 473-80. PMID 15254299 DOI: 10.1093/Protein/Gzh057  0.279
2002 Alkema WB, Dijkhuis AJ, De Vries E, Janssen DB. The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase. European Journal of Biochemistry. 269: 2093-100. PMID 11985586 DOI: 10.1046/J.1432-1033.2002.02857.X  0.278
1991 van den Wijngaard AJ, Reuvekamp PT, Janssen DB. Purification and characterization of haloalcohol dehalogenase from Arthrobacter sp. strain AD2. Journal of Bacteriology. 173: 124-9. PMID 1846134 DOI: 10.1128/jb.173.1.124-129.1991  0.278
1995 Pries F, Kingma J, Krooshof GH, Jeronimus-Stratingh CM, Bruins AP, Janssen DB. Histidine 289 is essential for hydrolysis of the alkyl-enzyme intermediate of haloalkane dehalogenase. The Journal of Biological Chemistry. 270: 10405-11. PMID 7737973 DOI: 10.1074/JBC.270.18.10405  0.278
2002 Alkema WB, Prins AK, de Vries E, Janssen DB. Role of alphaArg145 and betaArg263 in the active site of penicillin acylase of Escherichia coli. The Biochemical Journal. 365: 303-9. PMID 12071857 DOI: 10.1042/BJ20011468  0.275
2018 Schmidt M, Toplak A, Rozeboom HJ, Wijma HJ, Quaedflieg PJLM, van Maarseveen JH, Janssen DB, Nuijens T. Design of a substrate-tailored peptiligase variant for the efficient synthesis of thymosin-α1. Organic & Biomolecular Chemistry. PMID 29300408 DOI: 10.1039/c7ob02812a  0.275
2006 Janssen DB, Majerić-Elenkov M, Hasnaoui G, Hauer B, Lutje Spelberg JH. Enantioselective formation and ring-opening of epoxides catalysed by halohydrin dehalogenases. Biochemical Society Transactions. 34: 291-5. PMID 16545097 DOI: 10.1042/BST20060291  0.273
2006 Barends TR, Polderman-Tijmes JJ, Jekel PA, Williams C, Wybenga G, Janssen DB, Dijkstra BW. Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme. The Journal of Biological Chemistry. 281: 5804-10. PMID 16377627 DOI: 10.1074/Jbc.M511187200  0.272
1995 Pries F, Kingma J, Janssen DB. Activation of an Asp-124-->Asn mutant of haloalkane dehalogenase by hydrolytic deamidation of asparagine. Febs Letters. 358: 171-4. PMID 7828730 DOI: 10.1016/0014-5793(94)01420-6  0.27
1985 Keuning S, Janssen DB, Witholt B. Purification and characterization of hydrolytic haloalkane dehalogenase from Xanthobacter autotrophicus GJ10. Journal of Bacteriology. 163: 635-9. PMID 4019411 DOI: 10.1128/jb.163.2.635-639.1985  0.265
2021 Meng Q, Ramírez-Palacios C, Capra N, Hooghwinkel ME, Thallmair S, Rozeboom HJ, Thunnissen AWH, Wijma HJ, Marrink SJ, Janssen DB. Computational Redesign of an ω-Transaminase from for Asymmetric Synthesis of Enantiopure Bulky Amines. Acs Catalysis. 11: 10733-10747. PMID 34504735 DOI: 10.1021/acscatal.1c02053  0.265
2015 Diez V, Loznik M, Taylor S, Winn M, Rattray NJ, Podmore H, Micklefield J, Goodacre R, Medema MH, Müller U, Bovenberg R, Janssen DB, Takano E. Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block. Acs Synthetic Biology. 4: 796-807. PMID 25713978 DOI: 10.1021/Sb500368W  0.264
2013 Schallmey M, Floor RJ, Hauer B, Breuer M, Jekel PA, Wijma HJ, Dijkstra BW, Janssen DB. Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase. Chembiochem : a European Journal of Chemical Biology. 14: 870-81. PMID 23585096 DOI: 10.1002/cbic.201300005  0.262
2008 Jager SA, Shapovalova IV, Jekel PA, Alkema WB, Svedas VK, Janssen DB. Saturation mutagenesis reveals the importance of residues alphaR145 and alphaF146 of penicillin acylase in the synthesis of beta-lactam antibiotics. Journal of Biotechnology. 133: 18-26. PMID 17933411 DOI: 10.1016/j.jbiotec.2007.08.039  0.261
2020 Dong L, Meng Q, Ramírez-Palacios C, Wijma HJ, Marrink SJ, Janssen DB. Asymmetric Synthesis of Optically Pure Aliphatic Amines with an Engineered Robust ω-Transaminase Catalysts. 10: 1310. DOI: 10.3390/catal10111310  0.261
1999 van Hylckama Vlieg JE, Kingma J, Kruizinga W, Janssen DB. Purification of a glutathione S-transferase and a glutathione conjugate-specific dehydrogenase involved in isoprene metabolism in Rhodococcus sp. strain AD45. Journal of Bacteriology. 181: 2094-101. PMID 10094686 DOI: 10.1128/JB.181.7.2094-2101.1999  0.26
2001 Spelberg JH, van Hylckama Vlieg JE, Tang L, Janssen DB, Kellogg RM. Highly enantioselective and regioselective biocatalytic azidolysis of aromatic epoxides. Organic Letters. 3: 41-3. PMID 11429866 DOI: 10.1021/Ol0067540  0.257
2004 Gabor EM, Janssen DB. Increasing the synthetic performance of penicillin acylase PAS2 by structure-inspired semi-random mutagenesis. Protein Engineering, Design & Selection : Peds. 17: 571-9. PMID 15333773 DOI: 10.1093/protein/gzh070  0.256
2015 Heberling MM, Masman MF, Bartsch S, Wybenga GG, Dijkstra BW, Marrink SJ, Janssen DB. Ironing out their differences: dissecting the structural determinants of a phenylalanine aminomutase and ammonia lyase. Acs Chemical Biology. 10: 989-97. PMID 25494407 DOI: 10.1021/Cb500794H  0.255
1995 Janssen DB, van der Ploeg JR, Pries F. Genetics and biochemistry of 1,2-dichloroethane degradation. Biodegradation. 5: 249-57. PMID 7765836 DOI: 10.1007/BF00696463  0.254
2016 Gross J, Prokop Z, Janssen D, Faber K, Hall M. Regio- and Enantioselective Sequential Dehalogenation of rac-1,3-Dibromobutane by Haloalkane Dehalogenase LinB. Chembiochem : a European Journal of Chemical Biology. PMID 27223496 DOI: 10.1002/cbic.201600227  0.254
2005 Fraaije MW, Wu J, Heuts DP, van Hellemond EW, Spelberg JH, Janssen DB. Discovery of a thermostable Baeyer-Villiger monooxygenase by genome mining. Applied Microbiology and Biotechnology. 66: 393-400. PMID 15599520 DOI: 10.1007/s00253-004-1749-5  0.253
1998 Poelarends GJ, Wilkens M, Larkin MJ, van Elsas JD, Janssen DB. Degradation of 1,3-dichloropropene by pseudomonas cichorii 170. Applied and Environmental Microbiology. 64: 2931-6. PMID 9687453 DOI: 10.1128/AEM.64.8.2931-2936.1998  0.252
2009 Puthan Veetil V, Raj H, Quax WJ, Janssen DB, Poelarends GJ. Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1. The Febs Journal. 276: 2994-3007. PMID 19490103 DOI: 10.1111/j.1742-4658.2009.07015.x  0.251
2021 Toplak A, Teixeira de Oliveira EF, Schmidt M, Rozeboom HJ, Wijma HJ, Meekels LKM, de Visser R, Janssen DB, Nuijens T. From thiol-subtilisin to omniligase: Design and structure of a broadly applicable peptide ligase. Computational and Structural Biotechnology Journal. 19: 1277-1287. PMID 33717424 DOI: 10.1016/j.csbj.2021.02.002  0.25
1992 van der Ploeg J, van Hall G, Janssen DB. Characterization of the haloacid dehalogenase from Xanthobacter autotrophicus GJ10 and sequencing of the dhlB gene. Journal of Bacteriology. 173: 7925-33. PMID 1744048 DOI: 10.1128/jb.173.24.7925-7933.1991  0.249
2001 van Hylckama Vlieg JE, Tang L, Lutje Spelberg JH, Smilda T, Poelarends GJ, Bosma T, van Merode AE, Fraaije MW, Janssen DB. Halohydrin dehalogenases are structurally and mechanistically related to short-chain dehydrogenases/reductases. Journal of Bacteriology. 183: 5058-66. PMID 11489858 DOI: 10.1128/JB.183.17.5058-5066.2001  0.249
2002 Lutje Spelberg JH, Tang L, Van Gelder M, Kellogg RM, Janssen DB. Exploration of the biocatalytic potential of a halohydrin dehalogenase using chromogenic substrates Tetrahedron Asymmetry. 13: 1083-1089. DOI: 10.1016/S0957-4166(02)00222-7  0.249
2006 Elenkov MM, Hauer B, Janssen DB. Enantioselective Ring Opening of Epoxides with Cyanide Catalyzed by Halohydrin Dehalogenases: A New Approach to Non-Racemic β-Hydroxy Nitriles. Cheminform. 37. DOI: 10.1002/CHIN.200627033  0.248
2018 Otzen M, Palacio C, Janssen DB. Characterization of the caprolactam degradation pathway in Pseudomonas jessenii using mass spectrometry-based proteomics. Applied Microbiology and Biotechnology. PMID 29850960 DOI: 10.1007/s00253-018-9073-7  0.248
1997 Ridder IS, Rozeboom HJ, Kalk KH, Janssen DB, Dijkstra BW. Three-dimensional structure of L-2-haloacid dehalogenase from Xanthobacter autotrophicus GJ10 complexed with the substrate-analogue formate Journal of Biological Chemistry. 272: 33015-33022. PMID 9407083 DOI: 10.1074/Jbc.272.52.33015  0.247
2000 Alkema WBL, Hensgens CMH, Kroezinga EH, De Vries E, Floris R, Van Der Laan JM, Dijkstra BW, Janssen DB. Characterization of the β-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies Protein Engineering. 13: 857-863. PMID 11239085 DOI: 10.1093/Protein/13.12.857  0.245
1999 Rink R, Lutje Spelberg JH, Pieters RJ, Kingma J, Nardini M, Kellogg RM, Dijkstra BW, Janssen DB. Mutation of tyrosine residues involved in the alkylation half reaction of epoxide hydrolase from Agrobacterium radiobacter AD1 results in improved enantioselectivity [7] Journal of the American Chemical Society. 121: 7417-7418. DOI: 10.1021/Ja990501O  0.243
2016 Palacio CM, Crismaru CG, Bartsch S, Navickas V, Ditrich K, Breuer M, Abu R, Woodley J, Baldenius K, Wu B, Janssen DB. Enzymatic network for production of ether amines from alcohols. Biotechnology and Bioengineering. PMID 26915048 DOI: 10.1002/bit.25954  0.24
1999 Lutje Spelberg JH, Van Hylckama Vlieg JET, Bosma T, Kellogg RM, Janssen DB. A tandem enzyme reaction to produce optically active halohydrins, epoxides and diols Tetrahedron Asymmetry. 10: 2863-2870. DOI: 10.1016/S0957-4166(99)00308-0  0.238
2006 Majerić Elenkov M, Tang L, Hauer B, Janssen DB. Sequential kinetic resolution catalyzed by halohydrin dehalogenase. Organic Letters. 8: 4227-9. PMID 16956193 DOI: 10.1021/ol061369h  0.238
2003 Barends TR, Polderman-Tijmes JJ, Jekel PA, Hensgens CM, de Vries EJ, Janssen DB, Dijkstra BW. The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases. The Journal of Biological Chemistry. 278: 23076-84. PMID 12684501 DOI: 10.1074/Jbc.M302246200  0.238
2003 Fraaije MW, Kamerbeek NM, Heidekamp AJ, Fortin R, Janssen DB. The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase. The Journal of Biological Chemistry. 279: 3354-60. PMID 14610090 DOI: 10.1074/JBC.M307770200  0.238
2010 SPELBERG JHL, RINK R, KELLOGG RM, JANSSEN DB. ChemInform Abstract: Enantioselectivity of a Recombinant Epoxide Hydrolase from Agrobacterium radiobacter. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199827113  0.237
2001 Nardini M, Rink R, Janssen DB, Dijkstra BW. Structure and mechanism of the epoxide hydrolase from Agrobacterium radiobacter AD1 Journal of Molecular Catalysis - B Enzymatic. 11: 1035-1042. DOI: 10.1016/S1381-1177(00)00049-7  0.237
1998 Kaschabek SR, Kasberg T, Müller D, Mars AE, Janssen DB, Reineke W. Degradation of chloroaromatics: purification and characterization of a novel type of chlorocatechol 2,3-dioxygenase of Pseudomonas putida GJ31. Journal of Bacteriology. 180: 296-302. PMID 9440519 DOI: 10.1128/JB.180.2.296-302.1998  0.236
1995 Janssen DB, Pries F, van der Ploeg JR. Genetics and biochemistry of dehalogenating enzymes. Annual Review of Microbiology. 48: 163-91. PMID 7826004 DOI: 10.1146/ANNUREV.MI.48.100194.001115  0.236
2003 Barends TR, Hensgens CM, Polderman-Tijmes JJ, Jekel PA, de Vries E, Janssen DB, Dijkstra BW. X-ray analysis of two antibiotic-synthesizing bacterial ester hydrolases: preliminary results. Acta Crystallographica. Section D, Biological Crystallography. 59: 158-60. PMID 12499556 DOI: 10.1107/S090744490201836X  0.235
2010 Koetsier MJ, Gombert AK, Fekken S, Bovenberg RA, van den Berg MA, Kiel JA, Jekel PA, Janssen DB, Pronk JT, van der Klei IJ, Daran JM. The Penicillium chrysogenum aclA gene encodes a broad-substrate-specificity acyl-coenzyme A ligase involved in activation of adipic acid, a side-chain precursor for cephem antibiotics. Fungal Genetics and Biology : Fg & B. 47: 33-42. PMID 19833221 DOI: 10.1016/j.fgb.2009.10.003  0.234
2003 Prokop Z, Monincová M, Chaloupková R, Klvana M, Nagata Y, Janssen DB, Damborský J. Catalytic mechanism of the maloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26. The Journal of Biological Chemistry. 278: 45094-100. PMID 12952988 DOI: 10.1074/JBC.M307056200  0.233
2003 de Jong RM, Tiesinga JJ, Rozeboom HJ, Kalk KH, Tang L, Janssen DB, Dijkstra BW. Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site. The Embo Journal. 22: 4933-44. PMID 14517233 DOI: 10.1093/emboj/cdg479  0.231
2013 Di Toma C, Sonke T, Quaedflieg PJ, Volker Wagner AF, Janssen DB. Purification and use of E. coli peptide deformylase for peptide deprotection in chemoenzymatic peptide synthesis. Protein Expression and Purification. 89: 73-9. PMID 23357810 DOI: 10.1016/j.pep.2013.01.004  0.23
2006 Carboni C, Kierkels HG, Gardossi L, Tamiola K, Janssen DB, Quaedflieg PJ. Preparation of d-amino acids by enzymatic kinetic resolution using a mutant of penicillin-G acylase from E. coli Tetrahedron: Asymmetry. 17: 245-251. DOI: 10.1016/J.TETASY.2005.12.023  0.23
1988 Janssen DB, Gerritse J, Brackman J, Kalk C, Jager D, Witholt B. Purification and characterization of a bacterial dehalogenase with activity toward halogenated alkanes, alcohols and ethers Febs Journal. 171: 67-72. PMID 3338472 DOI: 10.1111/J.1432-1033.1988.Tb13759.X  0.229
2016 Beyer N, Kulig JK, Bartsch A, Hayes MA, Janssen DB, Fraaije MW. P450BM3 fused to phosphite dehydrogenase allows phosphite-driven selective oxidations. Applied Microbiology and Biotechnology. PMID 27900443 DOI: 10.1007/s00253-016-7993-7  0.228
2006 Elenkov M, Hauer B, Janssen D. Enantioselective Ring Opening of Epoxides with Cyanide Catalysed by Halohydrin Dehalogenases: A New Approach to Non-Racemic β-Hydroxy Nitriles Advanced Synthesis & Catalysis. 348: 579-585. DOI: 10.1002/ADSC.200505333  0.228
2004 Lutje Spelberg JH, Tang L, Kellogg RM, Janssen DB. Enzymatic dynamic kinetic resolution of epihalohydrins Tetrahedron Asymmetry. 15: 1095-1102. DOI: 10.1016/J.Tetasy.2004.02.009  0.228
2015 Mikleusevic A, Hamersak Z, Salopek-Sondi B, Tang L, Janssen DB, Majeric Elenkov M. ChemInform Abstract: Oxazolidinone Synthesis Through Halohydrin Dehalogenase-Catalyzed Dynamic Kinetic Resolution. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201540157  0.228
2001 Kamerbeek NM, Moonen MJ, Van Der Ven JG, Van Berkel WJ, Fraaije MW, Janssen DB. 4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB. A novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds. European Journal of Biochemistry. 268: 2547-57. PMID 11322873 DOI: 10.1046/J.1432-1327.2001.02137.X  0.228
2008 van Hellemond EW, van Dijk M, Heuts DP, Janssen DB, Fraaije MW. Discovery and characterization of a putrescine oxidase from Rhodococcus erythropolis NCIMB 11540. Applied Microbiology and Biotechnology. 78: 455-63. PMID 18183391 DOI: 10.1007/s00253-007-1310-4  0.227
2006 van Loo B, Kingma J, Arand M, Wubbolts MG, Janssen DB. Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis. Applied and Environmental Microbiology. 72: 2905-17. PMID 16597997 DOI: 10.1128/AEM.72.4.2905-2917.2006  0.225
2005 de Jong RM, Tiesinga JJ, Villa A, Tang L, Janssen DB, Dijkstra BW. Structural basis for the enantioselectivity of an epoxide ring opening reaction catalyzed by halo alcohol dehalogenase HheC. Journal of the American Chemical Society. 127: 13338-43. PMID 16173767 DOI: 10.1021/Ja0531733  0.224
2015 Mikleušević A, Hameršak Z, Salopek-Sondi B, Tang L, Janssen DB, Majerić Elenkov M. Oxazolidinone Synthesis through Halohydrin Dehalogenase- Catalyzed Dynamic Kinetic Resolution Advanced Synthesis & Catalysis. 357: 1709-1714. DOI: 10.1002/ADSC.201500111  0.224
2016 Toplak A, Nuijens T, Quaedflieg PJLM, Wu B, Janssen DB. Peptiligase, an Enzyme for Efficient Chemoenzymatic Peptide Synthesis and Cyclization in Water Advanced Synthesis & Catalysis. 358: 2140-2147. DOI: 10.1002/ADSC.201600017  0.224
1996 Schanstra JP, Kingma J, Janssen DB. Specificity and kinetics of haloalkane dehalogenase. The Journal of Biological Chemistry. 271: 14747-53. PMID 8662955 DOI: 10.1074/JBC.271.25.14747  0.222
1996 Schanstra JP, Ridder IS, Heimeriks GJ, Rink R, Poelarends GJ, Kalk KH, Dijkstra BW, Janssen DB. Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate range Biochemistry. 35: 13186-13195. PMID 8855957 DOI: 10.1021/Bi961151A  0.22
1998 Krooshof GH, Ridder IS, Tepper AW, Vos GJ, Rozeboom HJ, Kalk KH, Dijkstra BW, Janssen DB. Kinetic analysis and X-ray structure of haloalkane dehalogenase with a modified halide-binding site. Biochemistry. 37: 15013-23. PMID 9790663 DOI: 10.1021/Bi9815187  0.219
1999 Alkema WB, Floris R, Janssen DB. The use of chromogenic reference substrates for the kinetic analysis of penicillin acylases. Analytical Biochemistry. 275: 47-53. PMID 10542108 DOI: 10.1006/ABIO.1999.4300  0.218
2004 Kamerbeek NM, Fraaije MW, Janssen DB. Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases. European Journal of Biochemistry. 271: 2107-16. PMID 15153101 DOI: 10.1111/J.1432-1033.2004.04126.X  0.218
2020 Bracco P, Wijma HJ, Nicolai B, Buitrago JAR, Klünemann T, Vila A, Schrepfer P, Blankenfeldt W, Janssen DB, Schallmey A. CYP154C5 Regioselectivity in Steroid Hydroxylation Explored by Substrate Modifications and Protein Engineering*. Chembiochem : a European Journal of Chemical Biology. PMID 33145893 DOI: 10.1002/cbic.202000735  0.216
2000 Rink R, Kingma J, Lutje Spelberg JH, Janssen DB. Tyrosine residues serve as proton donor in the catalytic mechanism of epoxide hydrolase from Agrobacterium radiobacter. Biochemistry. 39: 5600-13. PMID 10820034 DOI: 10.1021/BI9922392  0.215
1999 Rink R, Janssen DB. Kinetic mechanism of the enantioselective conversion of styrene oxide by epoxide hydrolase from Agrobacterium radiobacter AD1. Biochemistry. 37: 18119-27. PMID 9922181 DOI: 10.1021/BI9817257  0.215
1984 Janssen DB, van der Drift C. Catabolite repression and nitrogen control of allantoin-degrading enzymes in Pseudomonas aeruginosa. Antonie Van Leeuwenhoek. 49: 501-8. PMID 6418068 DOI: 10.1007/BF00399328  0.215
1981 Janssen DB, Herst PM, Joosten HM, van der Drift C. Nitrogen control in Pseudomonas aeruginosa: a role for glutamine in the regulations of the synthesis of nadp-dependent glutamate dehydrogenase, urease and histidase. Archives of Microbiology. 128: 398-402. PMID 6111986 DOI: 10.1007/BF00405920  0.213
1999 Nardini M, Ridder IS, Rozeboom HJ, Kalk KH, Rink R, Janssen DB, Dijkstra BW. The x-ray structure of epoxide hydrolase from Agrobacterium radiobacter AD1. An enzyme to detoxify harmful epoxides. The Journal of Biological Chemistry. 274: 14579-86. PMID 10329649 DOI: 10.1074/Jbc.274.21.14579  0.213
2008 Torres Pazmiño DE, Baas BJ, Janssen DB, Fraaije MW. Kinetic mechanism of phenylacetone monooxygenase from Thermobifida fusca. Biochemistry. 47: 4082-93. PMID 18321069 DOI: 10.1021/bi702296k  0.21
2008 Elenkov MM, Hoeffken HW, Tang L, Hauer B, Janssen DB. ChemInform Abstract: Enzyme-Catalyzed Nucleophilic Ring Opening of Epoxides for the Preparation of Enantiopure Tertiary Alcohols. Cheminform. 39. DOI: 10.1002/CHIN.200807049  0.209
2008 Hasnaoui-Dijoux G, Majerić Elenkov M, Lutje Spelberg JH, Hauer B, Janssen DB. Catalytic promiscuity of halohydrin dehalogenase and its application in enantioselective epoxide ring opening. Chembiochem : a European Journal of Chemical Biology. 9: 1048-51. PMID 18357593 DOI: 10.1002/cbic.200700734  0.207
1996 Schanstra JP, Janssen DB. Kinetics of halide release of haloalkane dehalogenase: evidence for a slow conformational change. Biochemistry. 35: 5624-32. PMID 8639520 DOI: 10.1021/BI952904G  0.206
2002 Bosma T, Damborský J, Stucki G, Janssen DB. Biodegradation of 1,2,3-trichloropropane through directed evolution and heterologous expression of a haloalkane dehalogenase gene. Applied and Environmental Microbiology. 68: 3582-7. PMID 12089046 DOI: 10.1128/AEM.68.7.3582-3587.2002  0.204
1985 Janssen DB, Scheper A, Dijkhuizen L, Witholt B. Degradation of halogenated aliphatic compounds by Xanthobacter autotrophicus GJ10. Applied and Environmental Microbiology. 49: 673-7. PMID 3994371 DOI: 10.1128/aem.49.3.673-677.1985  0.203
2005 Tang L, Torres Pazmiño DE, Fraaije MW, de Jong RM, Dijkstra BW, Janssen DB. Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site. Biochemistry. 44: 6609-18. PMID 15850394 DOI: 10.1021/Bi047613Z  0.203
2013 Bracco P, Janssen DB, Schallmey A. Selective steroid oxyfunctionalisation by CYP154C5, a bacterial cytochrome P450. Microbial Cell Factories. 12: 95. PMID 24134652 DOI: 10.1186/1475-2859-12-95  0.203
2004 Janssen DB. Evolving haloalkane dehalogenases. Current Opinion in Chemical Biology. 8: 150-9. PMID 15062775 DOI: 10.1016/J.CBPA.2004.02.012  0.203
2007 Elenkov MM, Hoeffken HW, Tang L, Hauer B, Janssen D. Enzyme-Catalyzed Nucleophilic Ring Opening of Epoxides for the Preparation of Enantiopure Tertiary Alcohols Advanced Synthesis & Catalysis. 349: 2279-2285. DOI: 10.1002/ADSC.200700146  0.202
2008 Hasnaoui-Dijoux G, Majerić Elenkov M, Lutje Spelberg JH, Hauer B, Janssen DB. Cover Picture: Catalytic Promiscuity of Halohydrin Dehalogenase and its Application in Enantioselective Epoxide Ring Opening (ChemBioChem 7/2008) Chembiochem. 9: 1001-1001. DOI: 10.1002/CBIC.200890021  0.202
1999 Nardini M, Ridder I, Rozeboom H, Kalk K, Rink R, Janssen D, Dijkstra B. X-ray structure of epoxide hydrolase from Agrobacterium radiobacter AD1 : An enzyme to detoxify harmful epoxides Italian Journal of Biochemistry. 49: 15-15. DOI: 10.2210/Pdb1Ehy/Pdb  0.202
2017 Beyer N, Kulig JK, Fraaije MW, Hayes MA, Janssen D. Exploring PTDH-P450BM3 variants for the synthesis of drug metabolites. Chembiochem : a European Journal of Chemical Biology. PMID 29181885 DOI: 10.1002/cbic.201700470  0.201
2004 van Loo B, Spelberg JH, Kingma J, Sonke T, Wubbolts MG, Janssen DB. Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shuffling. Chemistry & Biology. 11: 981-90. PMID 15271356 DOI: 10.1016/j.chembiol.2004.04.019  0.2
2023 Jóźwik IK, Bombino E, Abdulmughni A, Hartz P, Rozeboom HJ, Wijma HJ, Kappl R, Janssen DB, Bernhardt R, Thunnissen AWH. Regio- and stereoselective steroid hydroxylation by CYP109A2 from Bacillus megaterium explored by X-ray crystallography and computational modeling. The Febs Journal. PMID 37453052 DOI: 10.1111/febs.16906  0.2
2007 Jager SA, Jekel PA, Janssen DB. Hybrid penicillin acylases with improved properties for synthesis of β-lactam antibiotics Enzyme and Microbial Technology. 40: 1335-1344. DOI: 10.1016/J.ENZMICTEC.2006.10.014  0.2
1997 Schanstra JP, Ridder A, Kingma J, Janssen DB. Influence of mutations of Val226 on the catalytic rate of haloalkane dehalogenase. Protein Engineering. 10: 53-61. PMID 9051734 DOI: 10.1093/PROTEIN/10.1.53  0.2
2021 Marjanovic A, Rozeboom HJ, de Vries MS, Mayer C, Otzen M, Wijma HJ, Janssen DB. Catalytic and structural properties of ATP-dependent caprolactamase from Pseudomonas jessenii. Proteins. PMID 33826169 DOI: 10.1002/prot.26082  0.199
2011 Schallmey A, den Besten G, Teune IG, Kembaren RF, Janssen DB. Characterization of cytochrome P450 monooxygenase CYP154H1 from the thermophilic soil bacterium Thermobifida fusca. Applied Microbiology and Biotechnology. 89: 1475-85. PMID 21057946 DOI: 10.1007/s00253-010-2965-9  0.199
2021 Wullich SC, Wijma HJ, Janssen DB, Fetzner S. Stabilizing AqdC, a Pseudomonas Quinolone Signal-Cleaving Dioxygenase from Mycobacteria, by FRESCO-Based Protein Engineering. Chembiochem : a European Journal of Chemical Biology. 22: 733-742. PMID 33058333 DOI: 10.1002/cbic.202000641  0.198
2007 Heuts DP, van Hellemond EW, Janssen DB, Fraaije MW. Discovery, characterization, and kinetic analysis of an alditol oxidase from Streptomyces coelicolor. The Journal of Biological Chemistry. 282: 20283-91. PMID 17517896 DOI: 10.1074/jbc.M610849200  0.197
2012 van Leeuwen JG, Wijma HJ, Floor RJ, van der Laan JM, Janssen DB. Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks. Chembiochem : a European Journal of Chemical Biology. 13: 137-48. PMID 22109980 DOI: 10.1002/cbic.201100579  0.197
2022 Ashworth MA, Bombino E, de Jong RM, Wijma HJ, Janssen DB, McLean KJ, Munro AW. Computation-Aided Engineering of Cytochrome P450 for the Production of Pravastatin. Acs Catalysis. 12: 15028-15044. PMID 36570080 DOI: 10.1021/acscatal.2c03974  0.197
2007 van Hellemond EW, Janssen DB, Fraaije MW. Discovery of a novel styrene monooxygenase originating from the metagenome. Applied and Environmental Microbiology. 73: 5832-9. PMID 17644649 DOI: 10.1128/AEM.02708-06  0.196
1997 Mars AE, Kasberg T, Kaschabek SR, van Agteren MH, Janssen DB, Reineke W. Microbial degradation of chloroaromatics: use of the meta-cleavage pathway for mineralization of chlorobenzene. Journal of Bacteriology. 179: 4530-7. PMID 9226262 DOI: 10.1128/jb.179.14.4530-4537.1997  0.196
2019 Schmidt M, Huang YH, Texeira de Oliveira EF, Toplak A, Wijma HJ, Janssen DB, van Maarseveen JH, Craik DJ, Nuijens T. Efficient Enzymatic Cyclization of Disulfide-rich Peptides using Peptiligases. Chembiochem : a European Journal of Chemical Biology. PMID 30735312 DOI: 10.1002/Cbic.201900033  0.196
2004 de Vries EJ, Janssen DB. Biocatalytic Conversion of Epoxides Cheminform. 35. DOI: 10.1002/CHIN.200412250  0.194
2009 van Loo B, Kingma J, Heyman G, Wittenaar A, Lutje Spelberg JH, Sonke T, Janssen DB. Improved enantioselective conversion of styrene epoxides and meso-epoxides through epoxide hydrolases with a mutated nucleophile-flanking residue Enzyme and Microbial Technology. 44: 145-153. DOI: 10.1016/J.ENZMICTEC.2008.09.016  0.194
2001 Pieters RJ, Lutje Spelberg JH, Kellogg RM, Janssen DB. The enantioselectivity of haloalkane dehalogenases Tetrahedron Letters. 42: 469-471. DOI: 10.1016/S0040-4039(00)01947-X  0.193
2011 Hasan SA, Ferreira MI, Koetsier MJ, Arif MI, Janssen DB. Complete biodegradation of 4-fluorocinnamic acid by a consortium comprising Arthrobacter sp. strain G1 and Ralstonia sp. strain H1. Applied and Environmental Microbiology. 77: 572-9. PMID 21097599 DOI: 10.1128/AEM.00393-10  0.193
2021 Ramírez-Palacios C, Wijma HJ, Thallmair S, Marrink SJ, Janssen DB. Computational Prediction of ω-Transaminase Specificity by a Combination of Docking and Molecular Dynamics Simulations. Journal of Chemical Information and Modeling. PMID 34653331 DOI: 10.1021/acs.jcim.1c00617  0.193
1996 Janssen DB, van der Ploeg JR, Pries F. Genetic adaptation of bacteria to halogenated aliphatic compounds. Environmental Health Perspectives. 29-32. PMID 8565904 DOI: 10.1289/EHP.95103S429  0.192
2008 Ferreira MI, Marchesi JR, Janssen DB. Degradation of 4-fluorophenol by Arthrobacter sp. strain IF1. Applied Microbiology and Biotechnology. 78: 709-17. PMID 18228015 DOI: 10.1007/s00253-008-1343-3  0.191
2020 Božić N, Rozeboom HJ, Lončar N, Slavić MŠ, Janssen DB, Vujčić Z. Characterization of the starch surface binding site on Bacillus paralicheniformis α-amylase. International Journal of Biological Macromolecules. 165: 1529-1539. PMID 33058974 DOI: 10.1016/j.ijbiomac.2020.10.025  0.19
2005 van den Heuvel RH, Tahallah N, Kamerbeek NM, Fraaije MW, van Berkel WJ, Janssen DB, Heck AJ. Coenzyme binding during catalysis is beneficial for the stability of 4-hydroxyacetophenone monooxygenase. The Journal of Biological Chemistry. 280: 32115-21. PMID 16049018 DOI: 10.1074/Jbc.M503758200  0.19
2023 Delgado-Arciniega E, Wijma HJ, Hummel C, Janssen D. Computationally supported inversion of ketoreductase stereoselectivity. Chembiochem : a European Journal of Chemical Biology. e202300032. PMID 36916211 DOI: 10.1002/cbic.202300032  0.189
1993 van der Waarde JJ, Kok R, Janssen DB. Degradation of 2-chloroallylalcohol by a Pseudomonas sp. Applied and Environmental Microbiology. 59: 528-35. PMID 8434917 DOI: 10.1128/aem.59.2.528-535.1993  0.188
2020 Arabnejad H, Bombino E, Colpa DI, Jekel PA, Trajkovic M, Wijma HJ, Janssen DB. Computational Design of Enantiocomplementary Epoxide Hydrolases for Asymmetric Synthesis of Aliphatic and Aromatic Diols. Chembiochem : a European Journal of Chemical Biology. 21: 1893-1904. PMID 31961471 DOI: 10.1002/cbic.201900726  0.188
1977 Van Venrooij WJ, Jansen RT, Janssen DB. Proteins present on polyadenylic acid segments of messenger ribonucleic acid in Ehrlich ascites-tumour cells [proceedings]. Biochemical Society Transactions. 5: 662-3. PMID 71254 DOI: 10.1042/BST0050662  0.188
2015 Wijma HJ, Floor RJ, Bjelic S, Marrink SJ, Baker D, Janssen DB. Enantioselective enzymes by computational design and in silico screening. Angewandte Chemie (International Ed. in English). 54: 3726-30. PMID 25651000 DOI: 10.1002/Anie.201411415  0.187
2001 Baldascini H, Ganzeveld KJ, Janssen DB, Beenackers AACM. Effect of mass transfer limitations on the enzymatic kinetic resolution of epoxides in a two-liquid-phase system Biotechnology and Bioengineering. 73: 44-54. PMID 11255151 DOI: 10.1002/1097-0290(20010405)73:1<44::Aid-Bit1035>3.0.Co;2-C  0.186
2010 van der Ploeg J, Smidt MP, Landa AS, Janssen DB. Identification of chloroacetaldehyde dehydrogenase involved in 1,2-dichloroethane degradation. Applied and Environmental Microbiology. 60: 1599-605. PMID 16349259 DOI: 10.1128/aem.60.5.1599-1605.1994  0.186
1994 Janssen DB, Schanstra JP. Engineering proteins for environmental applications. Current Opinion in Biotechnology. 5: 253-9. PMID 7765007 DOI: 10.1016/0958-1669(94)90026-4  0.185
2003 Tang L, Lutje Spelberg JH, Fraaije MW, Janssen DB. Kinetic mechanism and enantioselectivity of halohydrin dehalogenase from Agrobacterium radiobacter. Biochemistry. 42: 5378-86. PMID 12731879 DOI: 10.1021/BI0273361  0.183
1999 Mars AE, Kingma J, Kaschabek SR, Reineke W, Janssen DB. Conversion of 3-chlorocatechol by various catechol 2,3-dioxygenases and sequence analysis of the chlorocatechol dioxygenase region of Pseudomonas putida GJ31. Journal of Bacteriology. 181: 1309-18. PMID 9973359 DOI: 10.1128/JB.181.4.1309-1318.1999  0.182
2000 van Hylckama Vlieg JE, Leemhuis H, Spelberg JH, Janssen DB. Characterization of the gene cluster involved in isoprene metabolism in Rhodococcus sp. strain AD45. Journal of Bacteriology. 182: 1956-63. PMID 10715003 DOI: 10.1128/JB.182.7.1956-1963.2000  0.182
2013 Toplak A, Wu B, Fusetti F, Quaedflieg PJ, Janssen DB. Proteolysin, a novel highly thermostable and cosolvent-compatible protease from the thermophilic bacterium Coprothermobacter proteolyticus. Applied and Environmental Microbiology. 79: 5625-32. PMID 23851086 DOI: 10.1128/AEM.01479-13  0.182
2008 van Hellemond EW, Mazon H, Heck AJ, van den Heuvel RH, Heuts DP, Janssen DB, Fraaije MW. ADP competes with FAD binding in putrescine oxidase. The Journal of Biological Chemistry. 283: 28259-64. PMID 18678871 DOI: 10.1074/jbc.M803255200  0.181
2008 Heuts DP, Winter RT, Damsma GE, Janssen DB, Fraaije MW. The role of double covalent flavin binding in chito-oligosaccharide oxidase from Fusarium graminearum. The Biochemical Journal. 413: 175-83. PMID 18352858 DOI: 10.1042/BJ20071591  0.181
1995 Chen Q, Janssen DB, Witholt B. Growth on octane alters the membrane lipid fatty acids of Pseudomonas oleovorans due to the induction of alkB and synthesis of octanol. Journal of Bacteriology. 177: 6894-901. PMID 7592483 DOI: 10.1128/jb.177.23.6894-6901.1995  0.178
2014 van Beek HL, Wijma HJ, Fromont L, Janssen DB, Fraaije MW. Stabilization of cyclohexanone monooxygenase by a computationally designed disulfide bond spanning only one residue. Febs Open Bio. 4: 168-74. PMID 24649397 DOI: 10.1016/j.fob.2014.01.009  0.175
2001 van Hylckama Vlieg JE, Janssen DB. Formation and detoxification of reactive intermediates in the metabolism of chlorinated ethenes. Journal of Biotechnology. 85: 81-102. PMID 11165358 DOI: 10.1016/S0168-1656(00)00364-3  0.175
2005 Hasnaoui G, Lutje Spelberg JH, de Vries E, Tang L, Hauer B, Janssen DB. Nitrite-mediated hydrolysis of epoxides catalyzed by halohydrin dehalogenase from Agrobacterium radiobacter AD1: a new tool for the kinetic resolution of epoxides Tetrahedron: Asymmetry. 16: 1685-1692. DOI: 10.1016/J.TETASY.2005.03.021  0.173
1996 Van der Ploeg JR, Kingma J, De Vries EJ, Van der Ven JG, Janssen DB. Adaptation of Pseudomonas sp. GJ1 to 2-bromoethanol caused by overexpression of an NAD-dependent aldehyde dehydrogenase with low affinity for halogenated aldehydes. Archives of Microbiology. 165: 258-64. PMID 8639028 DOI: 10.1007/s002030050324  0.171
2007 Jin J, Mazon H, van den Heuvel RH, Janssen DB, Fraaije MW. Discovery of a eugenol oxidase from Rhodococcus sp. strain RHA1. The Febs Journal. 274: 2311-21. PMID 17419730 DOI: 10.1111/j.1742-4658.2007.05767.x  0.168
1980 Janssen DB, op den Camp HJ, Leenen PJ, van der Drift C. The enzymes of the ammonia assimilation in Pseudomonas aeruginosa. Archives of Microbiology. 124: 197-203. PMID 6102851 DOI: 10.1007/BF00427727  0.167
2002 Pikkemaat MG, Linssen AB, Berendsen HJ, Janssen DB. Molecular dynamics simulations as a tool for improving protein stability. Protein Engineering. 15: 185-92. PMID 11932489 DOI: 10.1093/Protein/15.3.185  0.166
1999 Poelarends GJ, van Hylckama Vlieg JE, Marchesi JR, Freitas Dos Santos LM, Janssen DB. Degradation of 1,2-dibromoethane by Mycobacterium sp. strain GP1. Journal of Bacteriology. 181: 2050-8. PMID 10094681 DOI: 10.1128/JB.181.7.2050-2058.1999  0.164
2010 van den Wijngaard AJ, Prins J, Smal AJ, Janssen DB. Degradation of 2-Chloroethylvinylether by Ancylobacter aquaticus AD25 and AD27. Applied and Environmental Microbiology. 59: 2777-83. PMID 16349032 DOI: 10.1128/aem.59.9.2777-2783.1993  0.164
2007 Heuts DP, Janssen DB, Fraaije MW. Changing the substrate specificity of a chitooligosaccharide oxidase from Fusarium graminearum by model-inspired site-directed mutagenesis. Febs Letters. 581: 4905-9. PMID 17900572 DOI: 10.1016/j.febslet.2007.09.019  0.164
2004 Tang L, van Merode AE, Lutje Spelberg JH, Fraaije MW, Janssen DB. Steady-state kinetics and tryptophan fluorescence properties of halohydrin dehalogenase from Agrobacterium radiobacter. Roles of W139 and W249 in the active site and halide-induced conformational change. Biochemistry. 42: 14057-65. PMID 14636074 DOI: 10.1021/BI034941A  0.161
2014 Wijma HJ, Floor RJ, Jekel PA, Baker D, Marrink SJ, Janssen DB. Computationally designed libraries for rapid enzyme stabilization Protein Engineering, Design and Selection. 27: 49-58. PMID 24402331 DOI: 10.1093/Protein/Gzt061  0.161
2010 van Hylckama VJ, de Koning W, Janssen DB. Transformation Kinetics of Chlorinated Ethenes by Methylosinus trichosporium OB3b and Detection of Unstable Epoxides by On-Line Gas Chromatography. Applied and Environmental Microbiology. 62: 3304-12. PMID 16535402 DOI: 10.1128/aem.62.9.3304-3312.1996  0.161
2007 Janssen DB. Biocatalysis by dehalogenating enzymes. Advances in Applied Microbiology. 61: 233-52. PMID 17448791 DOI: 10.1016/S0065-2164(06)61006-X  0.161
2008 Jin J, Mazon H, van den Heuvel RH, Heck AJ, Janssen DB, Fraaije MW. Covalent flavinylation of vanillyl-alcohol oxidase is an autocatalytic process. The Febs Journal. 275: 5191-200. PMID 18793324 DOI: 10.1111/j.1742-4658.2008.06649.x  0.16
2000 Sipkema EM, De Koning W, Ganzeveld KJ, Janssen DB, Beenackers AACM. NADH-regulated metabolic model for growth of Methylosinus trichosporium OB3b. Cometabolic degradation of trichloroethene and optimization of bioreactor system performance Biotechnology Progress. 16: 189-198. PMID 10753443 DOI: 10.1021/Bp990155E  0.159
1982 Janssen DB, Herst PM, Joosten HM, van der Drift C. Regulation of amidase formation in mutants from Pseudomonas aeruginosa PAO lacking glutamine synthetase activity. Archives of Microbiology. 131: 344-6. PMID 6126169 DOI: 10.1007/BF00411183  0.159
1990 Janssen DB, Pries F, van der Ploeg J, Kazemier B, Terpstra P, Witholt B. Cloning of 1,2-dichloroethane degradation genes of Xanthobacter autotrophicus GJ10 and expression and sequencing of the dhlA gene. Journal of Bacteriology. 171: 6791-9. PMID 2687254 DOI: 10.1128/jb.171.12.6791-6799.1989  0.158
1995 Kennes C, Pries F, Krooshof GH, Bokma E, Kingma J, Janssen DB. Replacement of Tryptophan Residues in Haloalkane Dehalogenase Reduces Halide Binding and Catalytic Activity European Journal of Biochemistry. 228: 403-407. DOI: 10.1111/J.1432-1033.1995.0403N.X  0.157
2003 Bosma T, Pikkemaat MG, Kingma J, Dijk J, Janssen DB. Steady-state and pre-steady-state kinetic analysis of halopropane conversion by a rhodococcus haloalkane dehalogenase. Biochemistry. 42: 8047-53. PMID 12834356 DOI: 10.1021/BI026907M  0.157
2013 Wijma HJ, Janssen DB. Computational design gains momentum in enzyme catalysis engineering. The Febs Journal. 280: 2948-60. PMID 23647554 DOI: 10.1111/febs.12324  0.157
1999 Pikkemaat MG, Ridder IS, Rozeboom HJ, Kalk KH, Dijkstra BW, Janssen DB. Crystallographic and kinetic evidence of a collision complex formed during halide import in haloalkane dehalogenase Biochemistry. 38: 12052-12061. PMID 10508409 DOI: 10.1021/Bi990849W  0.155
2001 Janssen DB, Oppentocht JE, Poelarends GJ. Microbial dehalogenation. Current Opinion in Biotechnology. 12: 254-8. PMID 11404103 DOI: 10.1016/s0958-1669(00)00208-1  0.154
2014 Wijma HJ, Marrink SJ, Janssen DB. Computationally efficient and accurate enantioselectivity modeling by clusters of molecular dynamics simulations. Journal of Chemical Information and Modeling. 54: 2079-92. PMID 24916632 DOI: 10.1021/ci500126x  0.154
1983 Janssen DB, Smits RA, van der Drift C. Allantoinase from Pseudomonas aeruginosa. Purification, properties and immunochemical characterization of its in vivo inactivation. Biochimica Et Biophysica Acta. 718: 212-9. PMID 6814497 DOI: 10.1016/0304-4165(82)90221-5  0.153
2009 Shapovalova IV, Alkema WB, Jamskova OV, De Vries E, Guranda DT, Janssen DB, Švedas VK. Mutation of Residue βF71 of Escherichia coli Penicillin Acylase Results in Enhanced Enantioselectivity and Improved Catalytic Properties Acta Naturae. 1: 94-98. DOI: 10.32607/20758251-2009-1-3-94-98  0.152
2002 Fraaije MW, Kamerbeek NM, van Berkel WJ, Janssen DB. Identification of a Baeyer-Villiger monooxygenase sequence motif. Febs Letters. 518: 43-7. PMID 11997015 DOI: 10.1016/S0014-5793(02)02623-6  0.152
2012 Arif MI, Samin G, van Leeuwen JG, Oppentocht J, Janssen DB. Novel dehalogenase mechanism for 2,3-dichloro-1-propanol utilization in Pseudomonas putida strain MC4. Applied and Environmental Microbiology. 78: 6128-36. PMID 22752160 DOI: 10.1128/AEM.00760-12  0.151
2015 van Beek HL, Beyer N, Janssen DB, Fraaije MW. Lyophilization conditions for the storage of monooxygenases. Journal of Biotechnology. 203: 41-4. PMID 25817248 DOI: 10.1016/j.jbiotec.2015.03.010  0.151
1999 Krooshof GH, Floris R, Tepper AW, Janssen DB. Thermodynamic analysis of halide binding to haloalkane dehalogenase suggests the occurrence of large conformational changes. Protein Science : a Publication of the Protein Society. 8: 355-60. PMID 10048328 DOI: 10.1110/PS.8.2.355  0.149
2009 van Bloois E, Winter RT, Janssen DB, Fraaije MW. Export of functional Streptomyces coelicolor alditol oxidase to the periplasm or cell surface of Escherichia coli and its application in whole-cell biocatalysis. Applied Microbiology and Biotechnology. 83: 679-87. PMID 19224207 DOI: 10.1007/s00253-009-1904-0  0.148
2015 Floor RJ, Wijma HJ, Jekel PA, Terwisscha van Scheltinga AC, Dijkstra BW, Janssen DB. X-ray crystallographic validation of structure predictions used in computational design for protein stabilization. Proteins. 83: 940-51. PMID 25739581 DOI: 10.1002/Prot.24791  0.147
2005 Janssen DB, Dinkla IJ, Poelarends GJ, Terpstra P. Bacterial degradation of xenobiotic compounds: evolution and distribution of novel enzyme activities. Environmental Microbiology. 7: 1868-82. PMID 16309386 DOI: 10.1111/j.1462-2920.2005.00966.x  0.147
2018 Wijma HJ, Fürst MJLJ, Janssen DB. A Computational Library Design Protocol for Rapid Improvement of Protein Stability: FRESCO. Methods in Molecular Biology (Clifton, N.J.). 1685: 69-85. PMID 29086304 DOI: 10.1007/978-1-4939-7366-8_5  0.147
1998 Lutje Spelberg JH, Rink R, Kellogg RM, Janssen DB. Enantioselectivity of a recombinant epoxide hydrolase from Agrobacterium radiobacter Tetrahedron Asymmetry. 9: 459-466. DOI: 10.1016/S0957-4166(98)00003-2  0.146
1982 Janssen DB, Habets WJ, Marugg JT, Van Der Drift C. Nitrogen control in Pseudomonas aeruginosa: mutants affected in the synthesis of glutamine synthetase, urease, and NADP-dependent glutamate dehydrogenase. Journal of Bacteriology. 151: 22-8. PMID 6123499 DOI: 10.1128/jb.151.1.22-28.1982  0.145
1999 Pieters RJ, Fennema M, Kellogg RM, Janssen DB. Design and synthesis of reagents for phage display screening of dehalogenases. Bioorganic & Medicinal Chemistry Letters. 9: 161-6. PMID 10021920 DOI: 10.1016/S0960-894X(98)00697-0  0.145
2020 Lee M, Rozeboom HJ, Keuning E, de Waal P, Janssen DB. Structure-based directed evolution improves growth on xylose by influencing in vivo enzyme performance. Biotechnology For Biofuels. 13: 5. PMID 31938040 DOI: 10.1186/s13068-019-1643-0  0.145
2000 Sipkema EM, De Koning W, Ganzeveld KJ, Janssen DB, Beenackers AACM. NADH-regulated metabolic model for growth of Methylosinus trichosporium OB3b. Model presentation, parameter estimation, and model validation Biotechnology Progress. 16: 176-188. PMID 10753442 DOI: 10.1021/Bp9901567  0.145
2000 van Hylckama Vlieg JE, Poelarends GJ, Mars AE, Janssen DB. Detoxification of reactive intermediates during microbial metabolism of halogenated compounds. Current Opinion in Microbiology. 3: 257-62. PMID 10851165 DOI: 10.1016/S1369-5274(00)00086-2  0.142
1979 van der Drift C, Janssen DB, van Wezenbeek PM. Hydrolysis and synthesis of ATP by membrane-bound ATPase from a motile Streptococcus. Archives of Microbiology. 119: 31-6. PMID 31147 DOI: 10.1007/BF00407924  0.14
2002 Pikkemaat MG, Janssen DB. Generating segmental mutations in haloalkane dehalogenase: a novel part in the directed evolution toolbox. Nucleic Acids Research. 30: E35-5. PMID 11937643 DOI: 10.1093/NAR/30.8.E35  0.139
1999 Sipkema EM, De Koning W, Van Hylckama Vlieg JET, Ganzeveld KJ, Janssen DB, Beenackers AACM. Trichloroethene degradation in a two-step system by Methylosinus trichosporium OB3b. Optimization of system performance: Use of formate and methane Biotechnology and Bioengineering. 63: 56-68. PMID 10099581 DOI: 10.1002/(Sici)1097-0290(19990405)63:1<56::Aid-Bit6>3.0.Co;2-F  0.139
1995 van der Ploeg J, Janssen DB. Sequence analysis of the upstream region of dhlB, the gene encoding haloalkanoic acid dehalogenase of Xanthobacter autotrophicus GJ10. Biodegradation. 6: 257-63. PMID 7580000 DOI: 10.1007/BF00700465  0.138
2008 Moonen MJ, Kamerbeek NM, Westphal AH, Boeren SA, Janssen DB, Fraaije MW, van Berkel WJ. Elucidation of the 4-hydroxyacetophenone catabolic pathway in Pseudomonas fluorescens ACB. Journal of Bacteriology. 190: 5190-8. PMID 18502868 DOI: 10.1128/JB.01944-07  0.137
2002 Dinkla IJ, Janssen DB. Simultaneous growth on citrate reduces the effects of iron limitation during toluene degradation in Pseudomonas. Microbial Ecology. 45: 97-107. PMID 12415420 DOI: 10.1007/s00248-002-2023-y  0.136
2001 Genzel Y, Archelas A, Lutje Spelberg JH, Janssen DB, Furstoss R. Microbiological transformations. Part 48: Enantioselective biohydrolysis of 2-, 3- and 4-pyridyloxirane at high substrate concentration using the Agrobacterium radiobacter AD1 epoxide hydrolase and its Tyr215Phe mutant Tetrahedron. 57: 2775-2779. DOI: 10.1016/S0040-4020(01)00146-6  0.136
2015 Colin PY, Kintses B, Gielen F, Miton CM, Fischer G, Mohamed MF, Hyvönen M, Morgavi DP, Janssen DB, Hollfelder F. Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics. Nature Communications. 6: 10008. PMID 26639611 DOI: 10.1038/Ncomms10008  0.133
1995 van der Ploeg J, Willemsen M, van Hall G, Janssen DB. Adaptation of Xanthobacter autotrophicus GJ10 to bromoacetate due to activation and mobilization of the haloacetate dehalogenase gene by insertion element IS1247. Journal of Bacteriology. 177: 1348-56. PMID 7868610 DOI: 10.1128/jb.177.5.1348-1356.1995  0.133
2006 de Jong RM, Kalk KH, Tang L, Janssen DB, Dijkstra BW. The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family. Journal of Bacteriology. 188: 4051-6. PMID 16707696 DOI: 10.1128/Jb.01866-05  0.132
2006 Carvalho MF, Ferreira MI, Moreira IS, Castro PM, Janssen DB. Degradation of fluorobenzene by Rhizobiales strain F11 via ortho cleavage of 4-fluorocatechol and catechol. Applied and Environmental Microbiology. 72: 7413-7. PMID 16980423 DOI: 10.1128/AEM.01162-06  0.131
1993 Verschueren KH, Kingma J, Rozeboom HJ, Kalk KH, Janssen DB, Dijkstra BW. Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry. 32: 9031-7. PMID 8369276 DOI: 10.1021/Bi00086A008  0.131
2016 Arabnejad H, Dal Lago M, Jekel PA, Floor RJ, Thunnissen AW, Terwisscha van Scheltinga AC, Wijma HJ, Janssen DB. A robust cosolvent-compatible halohydrin dehalogenase by computational library design. Protein Engineering, Design & Selection : Peds. PMID 27999093 DOI: 10.1093/protein/gzw068  0.129
2004 Gabor EM, de Vries EJ, Janssen DB. Construction, characterization, and use of small-insert gene banks of DNA isolated from soil and enrichment cultures for the recovery of novel amidases. Environmental Microbiology. 6: 948-58. PMID 15305920 DOI: 10.1111/j.1462-2920.2004.00643.x  0.129
2013 Di Toma C, Sonke T, Quaedflieg PJ, Volker Wagner A, Janssen DB. Corrigendum to “Purification and use of Escherichia coli peptide deformylase for peptide deprotection in chemoenzymatic peptide synthesis” [Protein Expr. Purif. 89 (2013) 73–79] Protein Expression and Purification. 90: 141. DOI: 10.1016/J.PEP.2013.06.001  0.128
1986 van der Drift C, Janssen DB. Regulation of enzymes under nitrogen control in Pseudomonas aeruginosa. Current Topics in Cellular Regulation. 26: 485-90. PMID 3935383 DOI: 10.1016/B978-0-12-152826-3.50045-0  0.128
2012 Hasan SA, Wietzes P, Janssen DB. Biodegradation kinetics of 4-fluorocinnamic acid by a consortium of Arthrobacter and Ralstonia strains. Biodegradation. 23: 117-25. PMID 21728015 DOI: 10.1007/s10532-011-9491-z  0.126
2021 Doble MV, Obrecht L, Joosten H, Lee M, Rozeboom HJ, Branigan E, Naismith JH, Janssen DB, Jarvis AG, Kamer PCJ. Engineering Thermostability in Artificial Metalloenzymes to Increase Catalytic Activity Acs Catalysis. 11: 3620-3627. DOI: 10.1021/ACSCATAL.0C05413  0.124
2024 Heesakkers J, Janssen D. Pelvic pain syndromes. Current Opinion in Urology. 34: 43. PMID 38321977 DOI: 10.1097/MOU.0000000000001156  0.12
2009 Ferreira MI, Iida T, Hasan SA, Nakamura K, Fraaije MW, Janssen DB, Kudo T. Analysis of two gene clusters involved in the degradation of 4-fluorophenol by Arthrobacter sp. strain IF1. Applied and Environmental Microbiology. 75: 7767-73. PMID 19837837 DOI: 10.1128/AEM.00171-09  0.119
2013 Wijma HJ, Floor RJ, Janssen DB. Structure- and sequence-analysis inspired engineering of proteins for enhanced thermostability. Current Opinion in Structural Biology. 23: 588-94. PMID 23683520 DOI: 10.1016/j.sbi.2013.04.008  0.118
2020 Meng Q, Capra N, Palacio CM, Lanfranchi E, Otzen M, van Schie LZ, Rozeboom HJ, Thunnissen AWH, Wijma HJ, Janssen DB. Robust ω-Transaminases by Computational Stabilization of the Subunit Interface. Acs Catalysis. 10: 2915-2928. PMID 32953233 DOI: 10.1021/acscatal.9b05223  0.118
1994 Schanstra JP, Rink R, Pries F, Janssen DB. Construction of an expression and site-directed mutagenesis system of haloalkane dehalogenase in Escherichia coli. Protein Expression and Purification. 4: 479-89. PMID 8251760 DOI: 10.1006/PREP.1993.1063  0.118
2017 Verhoeven MD, Lee M, Kamoen L, van den Broek M, Janssen DB, Daran JG, van Maris AJ, Pronk JT. Mutations in PMR1 stimulate xylose isomerase activity and anaerobic growth on xylose of engineered Saccharomyces cerevisiae by influencing manganese homeostasis. Scientific Reports. 7: 46155. PMID 28401919 DOI: 10.1038/srep46155  0.118
2017 Lee M, Rozeboom HJ, de Waal P, de Jong R, Dudek HM, Janssen DB. Metal-dependence of xylose isomerase from Piromyces sp. E2 explored by activity profiling and protein crystallography. Biochemistry. PMID 29045784 DOI: 10.1021/acs.biochem.7b00777  0.117
1987 Janssen DB, Jager D, Witholt B. Degradation of n-haloalkanes and alpha, omega-dihaloalkanes by wild-type and mutants of Acinetobacter sp. strain GJ70. Applied and Environmental Microbiology. 53: 561-6. PMID 3579270 DOI: 10.1128/aem.53.3.561-566.1987  0.116
2016 Nuijens T, Toplak A, Quaedflieg PJLM, Drenth J, Wu B, Janssen DB. Engineering a Diverse Ligase Toolbox for Peptide Segment Condensation Advanced Synthesis & Catalysis. 358: 4041-4048. DOI: 10.1002/ADSC.201600774  0.115
2014 Samin G, Pavlova M, Arif MI, Postema CP, Damborsky J, Janssen DB. A Pseudomonas putida strain genetically engineered for 1,2,3-trichloropropane bioremediation. Applied and Environmental Microbiology. 80: 5467-76. PMID 24973068 DOI: 10.1128/AEM.01620-14  0.114
2015 Schallmey M, Jekel P, Tang L, Majeri? Elenkov M, Höffken HW, Hauer B, Janssen DB. A single point mutation enhances hydroxynitrile synthesis by halohydrin dehalogenase. Enzyme and Microbial Technology. 70: 50-7. PMID 25659632 DOI: 10.1016/j.enzmictec.2014.12.009  0.111
2000 Poelarends GJ, Kulakov LA, Larkin MJ, van Hylckama Vlieg JE, Janssen DB. Roles of horizontal gene transfer and gene integration in evolution of 1,3-dichloropropene- and 1,2-dibromoethane-degradative pathways. Journal of Bacteriology. 182: 2191-9. PMID 10735862 DOI: 10.1128/JB.182.8.2191-2199.2000  0.11
1988 Rozeboom HJ, Kingma J, Janssen DB, Dijkstra BW. Crystallization of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10. Journal of Molecular Biology. 200: 611-2. PMID 3398051 DOI: 10.1016/0022-2836(88)90548-7  0.109
2002 Spelberg J, Rink R, Archelas A, Furstoss R, Janssen D. Biocatalytic Potential of the Epoxide Hydrolase from Agrobacterium radiobacter AD1 and a Mutant with Enhanced Enantioselectivity Advanced Synthesis & Catalysis. 344: 980-985. DOI: 10.1002/1615-4169(200210)344:9<980::AID-ADSC980>3.0.CO;2-A  0.109
1998 van Hylckama Vlieg JE, Kingma J, van den Wijngaard AJ, Janssen DB. A glutathione S-transferase with activity towards cis-1, 2-dichloroepoxyethane is involved in isoprene utilization by Rhodococcus sp. strain AD45. Applied and Environmental Microbiology. 64: 2800-5. PMID 9687433 DOI: 10.1128/AEM.64.8.2800-2805.1998  0.107
2012 Duque AF, Hasan SA, Bessa VS, Carvalho MF, Samin G, Janssen DB, Castro PM. Isolation and characterization of a Rhodococcus strain able to degrade 2-fluorophenol. Applied Microbiology and Biotechnology. 95: 511-20. PMID 22101783 DOI: 10.1007/s00253-011-3696-2  0.105
1992 van den Wijngaard AJ, van der Kamp KW, van der Ploeg J, Pries F, Kazemier B, Janssen DB. Degradation of 1,2-dichloroethane by Ancylobacter aquaticus and other facultative methylotrophs. Applied and Environmental Microbiology. 58: 976-83. PMID 1575500 DOI: 10.1128/aem.58.3.976-983.1992  0.105
1982 Janssen DB, Joosten HM, Herst PM, van der Drift C. Characterization of glutamine-requiring mutants of Pseudomonas aeruginosa. Journal of Bacteriology. 151: 1176-83. PMID 6125498 DOI: 10.1128/jb.151.3.1176-1183.1982  0.104
2014 van Beek HL, Wijma HJ, Fromont L, Janssen DB, Fraaije MW. Stabilization of cyclohexanone monooxygenase by a computationally designed disulfide bond spanning only one residue Febs Open Bio. 4: 168-174. DOI: 10.1016/j.fob.2014.01.009  0.104
2002 Noordman WH, Wachter JH, de Boer GJ, Janssen DB. The enhancement by surfactants of hexadecane degradation by Pseudomonas aeruginosa varies with substrate availability. Journal of Biotechnology. 94: 195-212. PMID 11796172 DOI: 10.1016/S0168-1656(01)00405-9  0.101
2002 de Jong RM, Rozeboom HJ, Kalk KH, Tang L, Janssen DB, Dijkstra BW. Crystallization and preliminary X-ray analysis of an enantioselective halohydrin dehalogenase from Agrobacterium radiobacter AD1. Acta Crystallographica. Section D, Biological Crystallography. 58: 176-8. PMID 11752805 DOI: 10.1107/S0907444901019618  0.099
1994 Dolfing J, van den Wijngaard AJ, Janssen DB. Microbiological aspects of the removal of chlorinated hydrocarbons from air. Biodegradation. 4: 261-82. PMID 7764923 DOI: 10.1007/BF00695974  0.098
2018 Atashgahi S, Liebensteiner MG, Janssen DB, Smidt H, Stams AJM, Sipkema D. Microbial Synthesis and Transformation of Inorganic and Organic Chlorine Compounds. Frontiers in Microbiology. 9: 3079. PMID 30619161 DOI: 10.3389/fmicb.2018.03079  0.098
2000 de Best JH, Hunneman P, Doddema HJ, Janssen DB, Harder W. Transformation of carbon tetrachloride in an anaerobic packed-bed reactor without addition of another electron donor. Biodegradation. 10: 287-95. PMID 10633544 DOI: 10.1023/A:1008309003059  0.096
2020 Janssen DB, Stucki G. Perspectives of genetically engineered microbes for groundwater bioremediation. Environmental Science. Processes & Impacts. 22: 487-499. PMID 32095798 DOI: 10.1039/c9em00601j  0.093
1994 Landa AS, Sipkema EM, Weijma J, Beenackers AACM, Dolfing J, Janssen DB. Cometabolic degradation of trichloroethylene by Pseudomonas cepacia G4 in a chemostat with toluene as the primary substrate Applied and Environmental Microbiology. 60: 3368-3374. PMID 7524444 DOI: 10.1128/Aem.60.9.3368-3374.1994  0.093
1999 Kulakov LA, Poelarends GJ, Janssen DB, Larkin MJ. Characterization of IS2112, a new insertion sequence from Rhodococcus, and its relationship with mobile elements belonging to the IS110 family. Microbiology (Reading, England). 561-568. PMID 10217489 DOI: 10.1099/13500872-145-3-561  0.092
2010 van den Wijngaard AJ, Wind RD, Janssen DB. Kinetics of bacterial growth on chlorinated aliphatic compounds. Applied and Environmental Microbiology. 59: 2041-8. PMID 16348981 DOI: 10.1128/aem.59.7.2041-2048.1993  0.091
2019 Lanfranchi E, Trajković M, Barta K, Vries JGd, Janssen DB. Cover Feature: Exploring the Selective Demethylation of Aryl Methyl Ethers with a Pseudomonas Rieske Monooxygenase (ChemBioChem 1/2019) Chembiochem. 20: 3-3. DOI: 10.1002/Cbic.201800747  0.091
2007 Torz M, Wietzes P, Beschkov V, Janssen DB. Metabolism of mono- and dihalogenated C1 and C2 compounds by Xanthobacter autotrophicus growing on 1,2-dichloroethane. Biodegradation. 18: 145-57. PMID 16758275 DOI: 10.1007/s10532-006-9050-1  0.091
2006 Panella L, Broos J, Jin J, Fraaije MW, Janssen DB, Jeronimus-Stratingh M, Feringa BL, Minnaard AJ, de Vries JG. Merging Homogeneous Catalysis with Biocatalysis; Papain as Hydrogenation Catalyst. Cheminform. 37. DOI: 10.1002/CHIN.200611218  0.09
2009 Kunze M, Zerlin KF, Retzlaff A, Pohl JO, Schmidt E, Janssen DB, Vilchez-Vargas R, Pieper DH, Reineke W. Degradation of chloroaromatics by Pseudomonas putida GJ31: assembled route for chlorobenzene degradation encoded by clusters on plasmid pKW1 and the chromosome. Microbiology (Reading, England). 155: 4069-4083. PMID 19744988 DOI: 10.1099/mic.0.032110-0  0.09
1995 Ridder IS, Rozeboom HJ, Kingma J, Janssen DB, Dijkstra BW. Crystallization and preliminary x-ray analysis of L-2-haloacid dehalogenase from Xanthobacter autotrophicus GJ10 Protein Science. 4: 2619-2620. PMID 8580854 DOI: 10.1002/Pro.5560041220  0.09
1999 Bosma T, Kruizinga E, de Bruin EJ, Poelarends GJ, Janssen DB. Utilization of trihalogenated propanes by Agrobacterium radiobacter AD1 through heterologous expression of the haloalkane dehalogenase from Rhodococcus sp. strain M15-3. Applied and Environmental Microbiology. 65: 4575-81. PMID 10508091 DOI: 10.1128/AEM.65.10.4575-4581.1999  0.089
2009 van Hellemond E, Vermote L, Koolen W, Sonke T, Zandvoort E, Heuts DP, Janssen D, Fraaije M. Exploring the Biocatalytic Scope of Alditol Oxidase fromStreptomyces coelicolor Advanced Synthesis & Catalysis. 351: 1523-1530. DOI: 10.1002/ADSC.200900176  0.086
1998 Sipkema EM, De Koning W, Ganzeveld KJ, Janssen DB, Beenackers AACM. Experimental pulse technique for the study of microbial kinetics in continuous culture Journal of Biotechnology. 64: 159-176. DOI: 10.1016/S0168-1656(98)00076-5  0.085
2002 Tang L, van Hylckama Vlieg JE, Lutje Spelberg JH, Fraaije MW, Janssen DB. Improved stability of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by replacement of cysteine residues Enzyme and Microbial Technology. 30: 251-258. DOI: 10.1016/S0141-0229(01)00488-4  0.085
2005 Gabor EM, De Vries EJ, Janssen DB. A novel penicillin acylase from the environmental gene pool with improved synthetic properties Enzyme and Microbial Technology. 36: 182-190. DOI: 10.1016/j.enzmictec.2004.04.021  0.083
2009 Zhang XZ, Hou RZ, Xu L, Huang YB, Ferrero M, Fernández S, Gotor V, Taylor A, Bhalla TC, Wijdeven MA, Kie?basi?ski P, Rutjes FPJT, Sugai T, Fujino A, Yamaguchi H, ... ... Janssen DB, et al. Enzymatic Selectivity in Synthetic Methods Practical Methods For Biocatalysis and Biotransformations. 165-169. DOI: 10.1002/9780470748589.ch5  0.083
2001 Dinkla IJ, Gabor EM, Janssen DB. Effects of iron limitation on the degradation of toluene by Pseudomonas strains carrying the tol (pWWO) plasmid. Applied and Environmental Microbiology. 67: 3406-12. PMID 11472911 DOI: 10.1128/AEM.67.8.3406-3412.2001  0.082
1995 Chen Q, Nijenhuis A, Preusting H, Dolfing J, Janssen DB, Witholt B. Effects of octane on the fatty acid composition and transition temperature of Pseudomonas oleovorans membrane lipids during growth in two-liquid-phase continuous cultures Enzyme and Microbial Technology. 17: 647-652. DOI: 10.1016/0141-0229(94)00106-2  0.082
2008 Carvalho MF, De Marco P, Duque AF, Pacheco CC, Janssen DB, Castro PM. Labrys portucalensis sp. nov., a fluorobenzene-degrading bacterium isolated from an industrially contaminated sediment in northern Portugal. International Journal of Systematic and Evolutionary Microbiology. 58: 692-8. PMID 18319480 DOI: 10.1099/ijs.0.65472-0  0.081
2010 Prokop Z, Sato Y, Brezovsky J, Mozga T, Chaloupkova R, Koudelakova T, Jerabek P, Stepankova V, Natsume R, van Leeuwen JG, Janssen DB, Florian J, Nagata Y, Senda T, Damborsky J. Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering. Angewandte Chemie (International Ed. in English). 49: 6111-5. PMID 20645368 DOI: 10.1002/Anie.201001753  0.08
2000 Poelarends GJ, Zandstra M, Bosma T, Kulakov LA, Larkin MJ, Marchesi JR, Weightman AJ, Janssen DB. Haloalkane-utilizing Rhodococcus strains isolated from geographically distinct locations possess a highly conserved gene cluster encoding haloalkane catabolism. Journal of Bacteriology. 182: 2725-31. PMID 10781539 DOI: 10.1128/JB.182.10.2725-2731.2000  0.078
1987 Janssen DB, Keuning S, Witholt B. Involvement of a Quinoprotein Alcohol Dehydrogenase and an NAD-dependent Aldehyde Dehydrogenase in 2-Chloroethanol Metabolism in Xanthobacter autotrophicus GJ10 Microbiology. 133: 85-92. DOI: 10.1099/00221287-133-1-85  0.077
1994 van den Wijngaard AJ, van der Kleij RG, Doornweerd RE, Janssen DB. Influence of organic nutrients and cocultures on the competitive behavior of 1,2-dichloroethane-degrading bacteria. Applied and Environmental Microbiology. 59: 3400-5. PMID 8250561 DOI: 10.1128/aem.59.10.3400-3405.1993  0.076
2010 Mars AE, Houwing J, Dolfing J, Janssen DB. Degradation of Toluene and Trichloroethylene by Burkholderia cepacia G4 in Growth-Limited Fed-Batch Culture. Applied and Environmental Microbiology. 62: 886-91. PMID 16535277 DOI: 10.1128/aem.62.3.886-891.1996  0.075
2002 Noordman WH, Janssen DB. Rhamnolipid stimulates uptake of hydrophobic compounds by Pseudomonas aeruginosa. Applied and Environmental Microbiology. 68: 4502-8. PMID 12200306 DOI: 10.1128/AEM.68.9.4502-4508.2002  0.073
2010 Van Hylckama VJ, De Koning W, Janssen DB. Effect of Chlorinated Ethene Conversion on Viability and Activity of Methylosinus trichosporium OB3b. Applied and Environmental Microbiology. 63: 4961-4. PMID 16535757 DOI: 10.1128/aem.63.12.4961-4964.1997  0.071
1986 Janssen DB, Witholt B. Developments in biotechnology of relevance to drinking water preparation. The Science of the Total Environment. 47: 121-35. PMID 3911412 DOI: 10.1016/0048-9697(85)90324-9  0.069
1997 de Best JH, Jongema H, Weijling A, Doddema HJ, Janssen DB, Harder W. Transformation of 1,1,1-trichloroethane in an anaerobic packed-bed reactor at various concentrations of 1,1,1-trichloroethane, acetate and sulfate Applied Microbiology and Biotechnology. 48: 417-423. DOI: 10.1007/s002530051073  0.068
2010 Mars AE, Prins GT, Wietzes P, de Koning W, Janssen DB. Effect of trichloroethylene on the competitive behavior of toluene-degrading bacteria. Applied and Environmental Microbiology. 64: 208-15. PMID 16349481 DOI: 10.1128/AEM.64.1.208-215.1998  0.067
1996 Chen Q, Janssen DB, Witholt B. Physiological changes and alk gene instability in Pseudomonas oleovorans during induction and expression of alk genes. Journal of Bacteriology. 178: 5508-12. PMID 8808943 DOI: 10.1128/jb.178.18.5508-5512.1996  0.066
1977 Janssen DB, Counotte-Potman AD, Van Venrooij WJ. Characterization of poly(A)-protein complexes isolated from free and membrane-bound polyribosomes of Ehrlich ascites tumor cells. Molecular Biology Reports. 3: 87-95. PMID 1034205 DOI: 10.1007/BF00357213  0.065
2016 Lago MD, Wijma HJ, van Scheltinga ACT, Janssen DB, Thunnissen AWH. Using X-ray crystallography to validate the computational design of enantioselective epoxide hydrolases Acta Crystallographica Section a Foundations and Advances. 72: s257-s257. DOI: 10.1107/S2053273316096108  0.065
2012 Samin G, Janssen DB. Transformation and biodegradation of 1,2,3-trichloropropane (TCP). Environmental Science and Pollution Research International. 19: 3067-78. PMID 22875418 DOI: 10.1007/s11356-012-0859-3  0.065
1998 Bosma T, Janssen DB. Conversion of chlorinated propanes by Methylosinus trichosporium OB3b expressing soluble methane monooxygenase Applied Microbiology and Biotechnology. 50: 105-112. DOI: 10.1007/s002530051263  0.064
2005 Janssen DB. Catalytic Antibodies. Edited by Ehud Keinan. Chembiochem. 6: 927-927. DOI: 10.1002/CBIC.200500126  0.063
2014 Masman MF, Heberling MM, Janssen DB. From Aminomutases to Ammonia Lyases: A Protein Engineering Study Biophysical Journal. 106: 655a. DOI: 10.1016/j.bpj.2013.11.3623  0.063
2005 de Best JH, Salminen E, Doddema HJ, Janssen DB, Harder W. Transformation of carbon tetrachloride under sulfate reducing conditions. Biodegradation. 8: 429-36. PMID 15765588 DOI: 10.1023/A:1008262225760  0.063
1990 Strotmann UJ, Pentenga M, Janssen DB. Degradation of 2-chloroethanol by wild type and mutants of Pseudomonas putida US2 Archives of Microbiology. 154: 294-300. DOI: 10.1007/BF00248970  0.061
2001 Heinemann C, van Hylckama Vlieg JE, Janssen DB, Busscher HJ, van der Mei HC, Reid G. Purification and characterization of a surface-binding protein from Lactobacillus fermentum RC-14 that inhibits adhesion of Enterococcus faecalis 1131. Fems Microbiology Letters. 190: 177-80. PMID 10981710 DOI: 10.1111/j.1574-6968.2000.tb09282.x  0.059
2004 Gabor EM, Alkema WB, Janssen DB. Quantifying the accessibility of the metagenome by random expression cloning techniques. Environmental Microbiology. 6: 879-86. PMID 15305913 DOI: 10.1111/j.1462-2920.2004.00640.x  0.058
2003 Gabor EM, de Vries EJ, Janssen DB. Efficient recovery of environmental DNA for expression cloning by indirect extraction methods. Fems Microbiology Ecology. 44: 153-63. PMID 19719633 DOI: 10.1016/S0168-6496(02)00462-2  0.056
2017 Bringel F, Postema CP, Mangenot S, Bibi-Triki S, Chaignaud P, Farhan Ul Haque M, Gruffaz C, Hermon L, Louhichi Y, Maucourt B, Muller EEL, Nadalig T, Lajus A, Rouy Z, Médigue C, ... ... Janssen DB, et al. Genome Sequence of the Dichloromethane-Degrading Bacterium Hyphomicrobium sp. Strain GJ21. Genome Announcements. 5. PMID 28751386 DOI: 10.1128/genomeA.00622-17  0.052
1989 Oldenhuis R, Kuijk L, Lammers A, Janssen D, Witholt B. Degradation of chlorinated and non-chlorinated aromatic solvents in soil suspensions by pure bacterial cultures Applied Microbiology and Biotechnology. 30. DOI: 10.1007/BF00264013  0.05
1998 Noordman WH, Ji W, Brusseau ML, Janssen DB. Effects of rhamnolipid biosurfactants on removal of phenanthrene from soil Environmental Science and Technology. 32: 1806-1812. DOI: 10.1021/Es970739H  0.045
1988 Janssen DB, Grobben G, Hoekstra R, Oldenhuis R, Witholt B. Degradation of trans-1,2-dichloroethene by mixed and pure cultures of methanotrophic bacteria Applied Microbiology and Biotechnology. 29: 392-399. DOI: 10.1007/BF00265825  0.044
2009 Moreira I, Carvalho M, Amorim C, Janssen D, Castro P. Degradation of difluorobenzenes by the wild strain Labrys portucalensis New Biotechnology. 25: S75. DOI: 10.1016/j.nbt.2009.06.324  0.043
2009 Carvalho M, de Marco P, Duque A, Pacheco C, Janssen D, Castro P. Labrys potucalensis, a bacterial strain with the capacity to degrade fluorobenzene New Biotechnology. 25: S68. DOI: 10.1016/J.NBT.2009.06.306  0.04
1999 Naested H, Fennema M, Hao L, Andersen M, Janssen DB, Mundy J. A bacterial haloalkane dehalogenase gene as a negative selectable marker in Arabidopsis. The Plant Journal : For Cell and Molecular Biology. 18: 571-6. PMID 10417708 DOI: 10.1046/j.1365-313x.1999.00477.x  0.038
2005 Baldascini H, Janssen DB. Interfacial inactivation of epoxide hydrolase in a two-liquid-phase system Enzyme and Microbial Technology. 36: 285-293. DOI: 10.1016/J.ENZMICTEC.2003.08.007  0.037
2000 Noordman WH, Bruining J, Wietzes P, Janssen DB. Facilitated transport of a PAH mixture by a rhamnolipid biosurfactant in porous silica matrices Journal of Contaminant Hydrology. 44: 119-140. DOI: 10.1016/S0169-7722(00)00097-8  0.032
1999 de Best JH, Hage A, Doddema HJ, Janssen DB, Harder W. Complete transformation of 1,1,1-trichloroethane to chloroethane by a methanogenic mixed population Applied Microbiology and Biotechnology. 51: 277-283. DOI: 10.1007/s002530051393  0.028
2023 van Ginkel C, Baars C, Heesakkers J, Martens F, Janssen D. Study protocol of a multicentre double-blind RCT, comparing a traditional RCT with an aggregated N-of-1 trial: GAG therapy Efficacy Trial Solution for Bladder pain syndrome/Interstitial cystitis (GETSBI study). Bmj Open. 13: e068546. PMID 37045569 DOI: 10.1136/bmjopen-2022-068546  0.026
1995 Verhagen C, Smit E, Janssen DB, Van Elsas JD. Bacterial dichloropropene degradation in soil; screening of soils and involvement of plasmids carrying the dhlA gene Soil Biology and Biochemistry. 27: 1547-1557. DOI: 10.1016/0038-0717(95)00105-N  0.026
2000 Noordman WH, De Boer GJ, Wietzes P, Volkering F, Janssen DB. Assessment of the Use of Partitioning and Interfacial Tracers To Determine the Content and Mass Removal Rates of Nonaqueous Phase Liquids Environmental Science & Technology. 34: 4301-4306. DOI: 10.1021/ES990098L  0.025
2000 Noordman WH, Brusseau ML, Janssen DB. Adsorption of a multicomponent rhamnolipid surfactant to soil Environmental Science and Technology. 34: 832-838. DOI: 10.1021/Es9909982  0.024
1994 van der Waarde JJ, Kok R, Janssen DB. Cometabolic degradation of chloroallyl alcohols in batch and continuous cultures Applied Microbiology and Biotechnology. 42: 158-166. DOI: 10.1007/BF00170240  0.024
2003 Kamerbeek N, Janssen D, van Berkel W, Fraaije M. Baeyer–Villiger Monooxygenases, an Emerging Family of Flavin-Dependent Biocatalysts Advanced Synthesis & Catalysis. 345: 667-678. DOI: 10.1002/ADSC.200303014  0.022
2021 Javan Balegh Marand A, Van Koeveringe GA, Janssen D, Vahed N, Vögeli TA, Heesakkers J, Hajebrahimi S, Rahnama'i MS. Urinary Microbiome and its Correlation with Disorders of the Genitourinary System. Urology Journal. 18: 259-270. PMID 33550579 DOI: 10.22037/uj.v16i7.5976  0.02
1989 Van Den Wijngaard AJ, Janssen DB, Witholt B. Degradation of Epichlorohydrin and Halohydrins by Bacterial Cultures Isolated from Freshwater Sediment Microbiology. 135: 2199-2208. DOI: 10.1099/00221287-135-8-2199  0.018
2023 van Ginkel C, Hurst RE, Janssen D. The urothelial barrier in interstitial cystitis/bladder pain syndrome: its form and function, an overview of preclinical models. Current Opinion in Urology. PMID 37933666 DOI: 10.1097/MOU.0000000000001147  0.01
2023 Baars C, van Ginkel C, Heesakkers J, Scholtes M, Martens F, Janssen D. The Burden of Urinary Tract Infections on Quality of Life and Healthcare in Patients with Interstitial Cystitis. Healthcare (Basel, Switzerland). 11. PMID 37893834 DOI: 10.3390/healthcare11202761  0.01
2023 Javan Balegh Marand A, Baars C, Heesakkers J, van den Munckhof E, Ghojazadeh M, Rahnama'i MS, Janssen D. Differences in the Urinary Microbiome of Patients with Overactive Bladder Syndrome with and without Detrusor Overactivity on Urodynamic Measurements. Life (Basel, Switzerland). 13. PMID 37240844 DOI: 10.3390/life13051199  0.01
2022 Te Dorsthorst M, Digesu A, van Kerrebroeck P, Elneil S, van Breda J, Janssen D, Martens F, van Balken M, Heesakkers J. Patient-tailored healthcare and tibial nerve neuromodulation in the treatment of patients with overactive bladder symptoms. Neurourology and Urodynamics. 41: 679-684. PMID 35019163 DOI: 10.1002/nau.24873  0.01
2021 Te Dorsthorst M, van Balken M, Janssen D, Heesakkers J, Martens F. Real-life patient experiences of TTNS in the treatment of overactive bladder syndrome. Therapeutic Advances in Urology. 13: 17562872211041470. PMID 34484428 DOI: 10.1177/17562872211041470  0.01
2021 Marand AJB, Bach C, Janssen D, Heesakkers J, Ghojazadeh M, Vögeli TA, Salehi-Pourmehr H, Mostafae H, Hajebrahimi S, Rahnama'i MS. Lower urinary tract signs and symptoms in patients with COVID-19. Bmc Infectious Diseases. 21: 706. PMID 34311703 DOI: 10.1186/s12879-021-06394-z  0.01
1978 van Venrooij WJ, Janssen DB. HnRNP particles. Molecular Biology Reports. 4: 3-8. PMID 642940 DOI: 10.1007/BF00775172  0.01
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