Kyle K. Biggar - Publications

Affiliations: 
2008-2013 Biology Carleton University, Ottawa, Canada 

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chopra A, Cho WC, Willmore WG, Biggar KK. Hypoxia-Inducible Lysine Methyltransferases: G9a and GLP Hypoxic Regulation, Non-histone Substrate Modification, and Pathological Relevance. Frontiers in Genetics. 11: 579636. PMID 33088284 DOI: 10.3389/Fgene.2020.579636  0.548
2020 Al-Attar R, Wu CW, Biggar KK, Storey KB. Carb-Loading: Freeze-Induced Activation of the Glucose-Responsive ChREBP Transcriptional Network in Wood Frogs. Physiological and Biochemical Zoology : Pbz. 93: 49-61. PMID 31742477 DOI: 10.1086/706463  0.795
2019 Chopra A, Adhikary H, Willmore WG, Biggar KK. Insights into The Function and Regulation of Jumonji C Lysine Demethylases as Hypoxic Responsive Enzymes. Current Protein & Peptide Science. PMID 31889485 DOI: 10.2174/1389203721666191231104225  0.57
2019 Biggar KK, Zhang J, Storey KB. Navigating oxygen deprivation: liver transcriptomic responses of the red eared slider turtle to environmental anoxia. Peerj. 7: e8144. PMID 31788367 DOI: 10.7717/peerj.8144  0.604
2019 Chopra A, Willmore WG, Biggar KK. Protein quantification and visualization via ultraviolet-dependent labeling with 2,2,2-trichloroethanol. Scientific Reports. 9: 13923. PMID 31558752 DOI: 10.1038/S41598-019-50385-9  0.544
2019 Le Tri D, Childers CL, Adam MK, Ben RN, Storey KB, Biggar KK. Characterization of ice recrystallization inhibition activity in the novel freeze-responsive protein Fr10 from freeze-tolerant wood frogs, Rana sylvatica. Journal of Thermal Biology. 84: 426-430. PMID 31466782 DOI: 10.1016/J.Jtherbio.2019.07.030  0.764
2018 Biggar KK, Luu BE, Wu CW, Pifferi F, Perret M, Storey KB. Identification of novel and conserved microRNA and their expression in the gray mouse lemur, Microcebus murinus, a primate capable of daily torpor. Gene. PMID 30103007 DOI: 10.1016/j.gene.2018.08.014  0.737
2018 Perry BW, Card DC, McGlothlin JW, Pasquesi GIM, Adams RH, Schield DR, Hales NR, Corbin AB, Demuth JP, Hoffmann FG, Vandewege MW, Schott RK, Bhattacharyya N, Chang BSW, Casewell NR, ... ... Biggar KK, et al. Molecular adaptations for sensing and securing prey and insight into amniote genome diversity from the garter snake genome. Genome Biology and Evolution. PMID 30060036 DOI: 10.1093/Gbe/Evy157  0.308
2018 Biggar KK, Storey KB. The evaluation of anoxia responsive E2F DNA binding activity in the red eared slider turtle, . Peerj. 6: e4755. PMID 29770276 DOI: 10.7717/peerj.4755  0.355
2017 Biggar KK, Storey KB. Functional impact of microRNA regulation in models of extreme stress adaptation. Journal of Molecular Cell Biology. PMID 29206937 DOI: 10.1093/jmcb/mjx053  0.436
2017 Biggar KK, Storey KB. Exploration of low temperature microRNA function in an anoxia tolerant vertebrate ectotherm, the red eared slider turtle (Trachemys scripta elegans). Journal of Thermal Biology. 68: 139-146. PMID 28689715 DOI: 10.1016/j.jtherbio.2016.09.008  0.446
2017 Moggridge J, Biggar K, Dawson N, Storey KB. Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics. Technology in Cancer Research & Treatment. 1533034617714149. PMID 28602127 DOI: 10.1177/1533034617714149  0.691
2017 Adema CM, Hillier LW, Jones CS, Loker ES, Knight M, Minx P, Oliveira G, Raghavan N, Shedlock A, do Amaral LR, Arican-Goktas HD, Assis JG, Baba EH, Baron OL, Bayne CJ, ... ... Biggar KK, et al. Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature Communications. 8: 15451. PMID 28508897 DOI: 10.1038/Ncomms15451  0.364
2017 Biggar KK, Dawson NJ, Storey KB. Native protein denaturation using urea Biotechniques. 62. DOI: 10.2144/000114501  0.696
2016 Luu BE, Biggar KK, Wu CW, Storey KB. Torpor-responsive expression of novel microRNAs regulating metabolism and other cellular pathways in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus. Febs Letters. PMID 27670641 DOI: 10.1002/1873-3468.12435  0.807
2016 Bansal S, Biggar KK, Krivoruchko A, Storey KB. Response of the JAK-STAT signaling pathway to oxygen deprivation in the red eared slider turtle, Trachemys scripta elegans. Gene. PMID 27502419 DOI: 10.1016/j.gene.2016.08.010  0.763
2016 Wu CW, Biggar KK, Luu BE, Szereszewski KE, Storey KB. Analysis of microRNA expression during the torpor-arousal cycle of a mammalian hibernator, the 13-lined ground squirrel. Physiological Genomics. physiolgenomics.0000. PMID 27084747 DOI: 10.1152/physiolgenomics.00005.2016  0.778
2016 Luu B, Biggar K, Wu C, Storey K. Hibr-miRs: Cold-sensitive novel microRNA in the hibernating 13-lined ground squirrel Cryobiology. 73: 430. DOI: 10.1016/J.Cryobiol.2016.09.121  0.772
2015 Schaap P, Barrantes I, Minx P, Sasaki N, Anderson RW, Bénard M, Biggar KK, Buchler NE, Bundschuh R, Chen X, Fronick C, Fulton L, Golderer G, Jahn N, Knoop V, et al. The Physarum polycephalum Genome Reveals Extensive Use of Prokaryotic Two-component and Metazoan-type Tyrosine Kinase Signaling. Genome Biology and Evolution. PMID 26615215 DOI: 10.1093/Gbe/Evv237  0.361
2015 Biggar KK, Storey KB. Low-temperature microRNA expression in the painted turtle, Chrysemys picta during freezing stress. Febs Letters. 589: 3665-70. PMID 26519560 DOI: 10.1016/j.febslet.2015.10.026  0.471
2015 Peace RJ, Biggar KK, Storey KB, Green JR. A framework for improving microRNA prediction in non-human genomes. Nucleic Acids Research. PMID 26163062 DOI: 10.1093/Nar/Gkv698  0.354
2015 Sullivan KJ, Biggar KK, Storey KB. Expression and Characterization of the Novel Gene fr47 during Freezing in the Wood Frog, Rana sylvatica. Biochemistry Research International. 2015: 363912. PMID 26101667 DOI: 10.1155/2015/363912  0.774
2015 Biggar KK, Wu CW, Tessier SN, Zhang J, Pifferi F, Perret M, Storey KB. Primate Torpor: Regulation of Stress-activated Protein Kinases During Daily Torpor in the Gray Mouse Lemur, Microcebus murinus. Genomics, Proteomics & Bioinformatics. 13: 81-90. PMID 26093282 DOI: 10.1016/J.Gpb.2015.03.002  0.796
2015 Biggar KK, Wu CW, Tessier SN, Zhang J, Pifferi F, Perret M, Storey KB. Modulation of Gene Expression in Key Survival Pathways During Daily Torpor in the Gray Mouse Lemur, Microcebus murinus. Genomics, Proteomics & Bioinformatics. 13: 111-8. PMID 26093281 DOI: 10.1016/J.Gpb.2015.03.001  0.795
2015 Zhang J, Tessier SN, Biggar KK, Wu CW, Pifferi F, Perret M, Storey KB. Regulation of Torpor in the Gray Mouse Lemur: Transcriptional and Translational Controls and Role of AMPK Signaling. Genomics, Proteomics & Bioinformatics. 13: 103-10. PMID 26092186 DOI: 10.1016/J.Gpb.2015.03.003  0.794
2015 Tessier SN, Zhang J, Biggar KK, Wu CW, Pifferi F, Perret M, Storey KB. Regulation of the PI3K/AKT Pathway and Fuel Utilization During Primate Torpor in the Gray Mouse Lemur, Microcebus murinus. Genomics, Proteomics & Bioinformatics. 13: 91-102. PMID 26092184 DOI: 10.1016/J.Gpb.2015.03.006  0.792
2015 Wu CW, Biggar KK, Zhang J, Tessier SN, Pifferi F, Perret M, Storey KB. Induction of Antioxidant and Heat Shock Protein Responses During Torpor in the Gray Mouse Lemur, Microcebus murinus. Genomics, Proteomics & Bioinformatics. 13: 119-26. PMID 26092183 DOI: 10.1016/J.Gpb.2015.03.004  0.794
2015 Biggar KK, Storey KB. Insight into post-transcriptional gene regulation: stress-responsive microRNAs and their role in the environmental stress survival of tolerant animals. The Journal of Experimental Biology. 218: 1281-9. PMID 25954040 DOI: 10.1242/jeb.104828  0.459
2015 Biggar KK, Biggar Y, Storey KB. Identification of a novel dehydration responsive gene, drp10, from the African clawed frog, Xenopus laevis. Journal of Experimental Zoology. Part a, Ecological Genetics and Physiology. 323: 375-81. PMID 25866033 DOI: 10.1002/jez.1930  0.444
2015 Sullivan KJ, Biggar KK, Storey KB. Transcript expression of the freeze responsive gene fr10 in Rana sylvatica during freezing, anoxia, dehydration, and development. Molecular and Cellular Biochemistry. 399: 17-25. PMID 25280399 DOI: 10.1007/s11010-014-2226-9  0.77
2014 Biggar KK, Storey KB. Insight into temperature-dependent microRNA function in mammalian hibernators: Perspectives on cold-influenced microRNA/target interaction. Temperature (Austin, Tex.). 1: 84-6. PMID 27582076 DOI: 10.4161/temp.29656  0.381
2014 Wu CW, Biggar KK, Storey KB. Expression profiling and structural characterization of microRNAs in adipose tissues of hibernating ground squirrels. Genomics, Proteomics & Bioinformatics. 12: 284-91. PMID 25526980 DOI: 10.1016/j.gpb.2014.08.003  0.721
2014 Biggar KK, Storey KB. New Approaches to Comparative and Animal Stress Biology Research in the Post-genomic Era: A Contextual Overview. Computational and Structural Biotechnology Journal. 11: 138-46. PMID 25408848 DOI: 10.1016/j.csbj.2014.09.006  0.399
2014 Biggar KK, Wu CW, Storey KB. High-throughput amplification of mature microRNAs in uncharacterized animal models using polyadenylated RNA and stem-loop reverse transcription polymerase chain reaction. Analytical Biochemistry. 462: 32-4. PMID 24929089 DOI: 10.1016/j.ab.2014.05.032  0.69
2014 Biggar KK, Storey KB. Identification and expression of microRNA in the brain of hibernating bats, Myotis lucifugus. Gene. 544: 67-74. PMID 24768722 DOI: 10.1016/j.gene.2014.04.048  0.473
2014 Rouble AN, Biggar KK, Storey KB. A high-throughput protocol for message RNA quantification using RNA dot-blots. Analytical Biochemistry. 452: 31-3. PMID 24560727 DOI: 10.1016/j.ab.2014.02.014  0.754
2014 Biggar KK, Dawson NJ, Storey KB. P07 Cryobiology. 69: 197. DOI: 10.1016/j.cryobiol.2014.06.059  0.67
2013 Wu CW, Biggar KK, Storey KB. Dehydration mediated microRNA response in the African clawed frog Xenopus laevis. Gene. 529: 269-75. PMID 23958654 DOI: 10.1016/j.gene.2013.07.064  0.719
2013 Dawson NJ, Biggar KK, Storey KB. Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure. Plos One. 8: e68830. PMID 23874782 DOI: 10.1371/journal.pone.0068830  0.748
2013 Biggar KK, Kotani E, Furusawa T, Storey KB. Expression of freeze-responsive proteins, Fr10 and Li16, from freeze-tolerant frogs enhances freezing survival of BmN insect cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3376-83. PMID 23657819 DOI: 10.1096/fj.13-230573  0.416
2013 Shaffer HB, Minx P, Warren DE, Shedlock AM, Thomson RC, Valenzuela N, Abramyan J, Amemiya CT, Badenhorst D, Biggar KK, Borchert GM, Botka CW, Bowden RM, Braun EL, Bronikowski AM, et al. The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biology. 14: R28. PMID 23537068 DOI: 10.1186/Gb-2013-14-3-R28  0.36
2013 Zhang J, Biggar KK, Storey KB. Regulation of p53 by reversible post-transcriptional and post-translational mechanisms in liver and skeletal muscle of an anoxia tolerant turtle, Trachemys scripta elegans. Gene. 513: 147-55. PMID 23124036 DOI: 10.1016/j.gene.2012.10.049  0.674
2012 Biggar KK, Kornfeld SF, Maistrovski Y, Storey KB. MicroRNA regulation in extreme environments: differential expression of microRNAs in the intertidal snail Littorina littorea during extended periods of freezing and anoxia. Genomics, Proteomics & Bioinformatics. 10: 302-9. PMID 23200140 DOI: 10.1016/j.gpb.2012.09.002  0.751
2012 Kornfeld SF, Biggar KK, Storey KB. Differential expression of mature microRNAs involved in muscle maintenance of hibernating little brown bats, Myotis lucifugus: a model of muscle atrophy resistance. Genomics, Proteomics & Bioinformatics. 10: 295-301. PMID 23200139 DOI: 10.1016/j.gpb.2012.09.001  0.495
2012 Biggar KK, Dawson NJ, Storey KB. Real-time protein unfolding: a method for determining the kinetics of native protein denaturation using a quantitative real-time thermocycler. Biotechniques. 53: 231-8. PMID 23046506 DOI: 10.2144/0000113922  0.706
2012 Maistrovski Y, Biggar KK, Storey KB. HIF-1α regulation in mammalian hibernators: role of non-coding RNA in HIF-1α control during torpor in ground squirrels and bats. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. 182: 849-59. PMID 22526261 DOI: 10.1007/s00360-012-0662-y  0.752
2012 Biggar KK, Storey KB. Evidence for cell cycle suppression and microRNA regulation of cyclin D1 during anoxia exposure in turtles. Cell Cycle (Georgetown, Tex.). 11: 1705-13. PMID 22510561 DOI: 10.4161/cc.19790  0.462
2011 Roufayel R, Biggar KK, Storey KB. Regulation of cell cycle components during exposure to anoxia or dehydration stress in the wood frog, Rana sylvatica. Journal of Experimental Zoology. Part a, Ecological Genetics and Physiology. 315: 487-94. PMID 21796797 DOI: 10.1002/jez.696  0.791
2011 Biggar KK, Kornfeld SF, Storey KB. Amplification and sequencing of mature microRNAs in uncharacterized animal models using stem-loop reverse transcription-polymerase chain reaction. Analytical Biochemistry. 416: 231-3. PMID 21651887 DOI: 10.1016/j.ab.2011.05.015  0.386
2011 Biggar KK, Storey KB. Perspectives in cell cycle regulation: lessons from an anoxic vertebrate. Current Genomics. 10: 573-84. PMID 20514219 DOI: 10.2174/138920209789503905  0.409
2010 Biggar KK, Storey KB. The emerging roles of microRNAs in the molecular responses of metabolic rate depression. Journal of Molecular Cell Biology. 3: 167-75. PMID 21177365 DOI: 10.1093/jmcb/mjq045  0.489
2009 Biggar KK, Dubuc A, Storey K. MicroRNA regulation below zero: differential expression of miRNA-21 and miRNA-16 during freezing in wood frogs. Cryobiology. 59: 317-21. PMID 19735650 DOI: 10.1016/J.Cryobiol.2009.08.009  0.543
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