| Year |
Citation |
Score |
| 2024 |
Dutta D, Lorenzo-Martín LF, Rivest F, Broguiere N, Tillard L, Ragusa S, Brandenberg N, Höhnel S, Saugy D, Rusakiewicz S, Homicsko K, Coukos G, Lutolf MP. Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed colorectal cancer tumoroids. Npj Precision Oncology. 8: 179. PMID 39143103 DOI: 10.1038/s41698-024-00661-3 |
0.662 |
|
| 2024 |
Lorenzo-Martín LF, Broguiere N, Langer J, Tillard L, Nikolaev M, Coukos G, Homicsko K, Lutolf MP. Patient-derived mini-colons enable long-term modeling of tumor-microenvironment complexity. Nature Biotechnology. PMID 38956326 DOI: 10.1038/s41587-024-02301-4 |
0.694 |
|
| 2024 |
Liu YC, Ansaryan S, Tan J, Broguiere N, Lorenzo-Martín LF, Homicsko K, Coukos G, Lütolf MP, Altug H. Nanoplasmonic Single-Tumoroid Microarray for Real-Time Secretion Analysis. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2401539. PMID 38924371 DOI: 10.1002/advs.202401539 |
0.686 |
|
| 2024 |
Mitrofanova O, Nikolaev M, Xu Q, Broguiere N, Cubela I, Camp JG, Bscheider M, Lutolf MP. Bioengineered human colon organoids with in vivo-like cellular complexity and function. Cell Stem Cell. PMID 38876106 DOI: 10.1016/j.stem.2024.05.007 |
0.707 |
|
| 2024 |
Lorenzo-Martín LF, Hübscher T, Bowler AD, Broguiere N, Langer J, Tillard L, Nikolaev M, Radtke F, Lutolf MP. Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo. Nature. 629: 450-457. PMID 38658753 DOI: 10.1038/s41586-024-07330-2 |
0.717 |
|
| 2023 |
Girgin M, Broguiere N, Mattolini L, Lutolf M. A New Approach to Generate Gastruloids to Develop Anterior Neural Tissues. Bio-Protocol. 13: e4722. PMID 37497450 DOI: 10.21769/BioProtoc.4722 |
0.719 |
|
| 2022 |
Tischler J, Swank Z, Hsiung HA, Vianello S, Lutolf MP, Maerkl SJ. An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates. Cell Reports Methods. 2: 100244. PMID 35880022 DOI: 10.1016/j.crmeth.2022.100244 |
0.315 |
|
| 2022 |
Gonzalez DM, Schrode N, Ebrahim TAM, Broguiere N, Rossi G, Drakhlis L, Zweigerdt R, Lutolf MP, Beaumont KG, Sebra R, Dubois NC. Dissecting mechanisms of chamber-specific cardiac differentiation and its perturbation following retinoic acid exposure. Development (Cambridge, England). PMID 35686629 DOI: 10.1242/dev.200557 |
0.666 |
|
| 2021 |
Chrisnandy A, Blondel D, Rezakhani S, Broguiere N, Lutolf MP. Synthetic dynamic hydrogels promote degradation-independent in vitro organogenesis. Nature Materials. PMID 34782747 DOI: 10.1038/s41563-021-01136-7 |
0.712 |
|
| 2021 |
Girgin MU, Broguiere N, Hoehnel S, Brandenberg N, Mercier B, Arias AM, Lutolf MP. Bioengineered embryoids mimic post-implantation development in vitro. Nature Communications. 12: 5140. PMID 34446708 DOI: 10.1038/s41467-021-25237-8 |
0.708 |
|
| 2021 |
LeSavage BL, Suhar RA, Broguiere N, Lutolf MP, Heilshorn SC. Next-generation cancer organoids. Nature Materials. PMID 34385685 DOI: 10.1038/s41563-021-01057-5 |
0.671 |
|
| 2021 |
Rezakhani S, Gjorevski N, Lutolf MP. Extracellular matrix requirements for gastrointestinal organoid cultures. Biomaterials. 276: 121020. PMID 34280822 DOI: 10.1016/j.biomaterials.2021.121020 |
0.311 |
|
| 2021 |
Girgin MU, Broguiere N, Mattolini L, Lutolf MP. Gastruloids generated without exogenous Wnt activation develop anterior neural tissues. Stem Cell Reports. 16: 1143-1155. PMID 33891872 DOI: 10.1016/j.stemcr.2021.03.017 |
0.692 |
|
| 2020 |
Luisier R, Girgin M, Lutolf MP, Ranga A. Mammary epithelial morphogenesis in 3D combinatorial microenvironments. Scientific Reports. 10: 21635. PMID 33303789 DOI: 10.1038/s41598-020-78432-w |
0.307 |
|
| 2020 |
Rossi G, Broguiere N, Miyamoto M, Boni A, Guiet R, Girgin M, Kelly RG, Kwon C, Lutolf MP. Capturing Cardiogenesis in Gastruloids. Cell Stem Cell. PMID 33176168 DOI: 10.1016/j.stem.2020.10.013 |
0.701 |
|
| 2020 |
Nikolaev M, Mitrofanova O, Broguiere N, Geraldo S, Dutta D, Tabata Y, Elci B, Brandenberg N, Kolotuev I, Gjorevski N, Clevers H, Lutolf MP. Homeostatic mini-intestines through scaffold-guided organoid morphogenesis. Nature. 585: 574-578. PMID 32939089 DOI: 10.1038/S41586-020-2724-8 |
0.72 |
|
| 2020 |
Brandenberg N, Hoehnel S, Kuttler F, Homicsko K, Ceroni C, Ringel T, Gjorevski N, Schwank G, Coukos G, Turcatti G, Lutolf MP. High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays. Nature Biomedical Engineering. PMID 32514094 DOI: 10.1038/s41551-020-0565-2 |
0.301 |
|
| 2020 |
Broguiere N, Lüchtefeld I, Trachsel L, Mazunin D, Rizzo R, Bode JW, Lutolf MP, Zenobi-Wong M. Morphogenesis Guided by 3D Patterning of Growth Factors in Biological Matrices. Advanced Materials (Deerfield Beach, Fla.). e1908299. PMID 32390195 DOI: 10.1002/Adma.201908299 |
0.708 |
|
| 2020 |
Broguiere N, Lüchtefeld I, Trachsel L, Mazunin D, Rizzo R, Bode JW, Lutolf MP, Zenobi‐Wong M. Tissue Engineering: Morphogenesis Guided by 3D Patterning of Growth Factors in Biological Matrices (Adv. Mater. 25/2020) Advanced Materials. 32: 2070193. DOI: 10.1002/Adma.202070193 |
0.682 |
|
| 2019 |
Licht C, Rose J, Omidinia Anarkoli A, Blondel D, Roccio M, Haraszti T, Gehlen DB, Hubbell JA, Lutolf MP, De Laporte L. Synthetic 3D PEG-Anisogels tailored with fibronectin fragments induce aligned nerve extension. Biomacromolecules. PMID 31614080 DOI: 10.1021/Acs.Biomac.9B00891 |
0.463 |
|
| 2019 |
Ishihara J, Ishihara A, Starke RD, Peghaire CR, Smith KE, McKinnon TA, Tabata Y, Sasaki K, White MJ, Fukunaga K, Laffan MA, Lutolf MP, Randi AM, Hubbell JA. The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing. Blood. PMID 30975637 DOI: 10.1182/Blood.2019000510 |
0.417 |
|
| 2019 |
Vardar E, Vythilingam G, Pinnagoda K, Engelhardt EM, Zambelli PY, Hubbell JA, Lutolf MP, Frey P, Larsson HM. A bioactive injectable bulking material; a potential therapeutic approach for stress urinary incontinence. Biomaterials. 206: 41-48. PMID 30925287 DOI: 10.1016/J.Biomaterials.2019.03.030 |
0.416 |
|
| 2017 |
Vardar E, Larsson HM, Allazetta S, Engelhardt EM, Pinnagoda K, Vythilingam G, Hubbell JA, Lutolf MP, Frey P. Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment. Acta Biomaterialia. 67: 156-166. PMID 29197579 DOI: 10.1016/J.Actbio.2017.11.034 |
0.492 |
|
| 2017 |
Gjorevski N, Lutolf MP. Synthesis and characterization of well-defined hydrogel matrices and their application to intestinal stem cell and organoid culture. Nature Protocols. 12: 2263-2274. PMID 28981121 DOI: 10.1038/Nprot.2017.095 |
0.359 |
|
| 2017 |
Ishihara K, Ranga A, Lutolf MP, Tanaka EM, Meinhardt A. Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1597: 43-55. PMID 28361309 DOI: 10.1007/978-1-4939-6949-4_4 |
0.322 |
|
| 2016 |
Gjorevski N, Sachs N, Manfrin A, Giger S, Bragina ME, Ordóñez-Morán P, Clevers H, Lutolf MP. Designer matrices for intestinal stem cell and organoid culture. Nature. PMID 27851739 DOI: 10.1038/Nature20168 |
0.338 |
|
| 2016 |
Ranga A, Girgin M, Meinhardt A, Eberle D, Caiazzo M, Tanaka EM, Lutolf MP. Neural tube morphogenesis in synthetic 3D microenvironments. Proceedings of the National Academy of Sciences of the United States of America. PMID 27742791 DOI: 10.1073/pnas.1603529113 |
0.306 |
|
| 2016 |
Ranga A, Lutolf MP, Hilborn J, Ossipov DA. Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction. Biomacromolecules. 17: 1553-60. PMID 27014785 DOI: 10.1021/acs.biomac.5b01587 |
0.333 |
|
| 2015 |
Allazetta S, Kolb L, Zerbib S, Bardy J, Lutolf MP. Cell-Instructive Microgels with Tailor-Made Physicochemical Properties. Small (Weinheim An Der Bergstrasse, Germany). 11: 5647-56. PMID 26349486 DOI: 10.1002/smll.201501001 |
0.309 |
|
| 2015 |
Lienemann PS, Devaud YR, Reuten R, Simona BR, Karlsson M, Weber W, Koch M, Lutolf MP, Milleret V, Ehrbar M. Locally controlling mesenchymal stem cell morphogenesis by 3D PDGF-BB gradients towards the establishment of an in vitro perivascular niche. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 101-11. PMID 25385042 DOI: 10.1039/c4ib00152d |
0.331 |
|
| 2014 |
Mosiewicz KA, Kolb L, van der Vlies AJ, Lutolf MP. Microscale patterning of hydrogel stiffness through light-triggered uncaging of thiols. Biomaterials Science. 2: 1640-1651. PMID 32481945 DOI: 10.1039/c4bm00262h |
0.306 |
|
| 2014 |
Tabata Y, Horiguchi I, Lutolf MP, Sakai Y. Development of bioactive hydrogel capsules for the 3D expansion of pluripotent stem cells in bioreactors. Biomaterials Science. 2: 176-183. PMID 32481877 DOI: 10.1039/c3bm60183h |
0.312 |
|
| 2014 |
Ranga A, Gobaa S, Okawa Y, Mosiewicz K, Negro A, Lutolf MP. 3D niche microarrays for systems-level analyses of cell fate. Nature Communications. 5: 4324. PMID 25027775 DOI: 10.1038/ncomms5324 |
0.307 |
|
| 2014 |
Gjorevski N, Ranga A, Lutolf MP. Bioengineering approaches to guide stem cell-based organogenesis. Development (Cambridge, England). 141: 1794-804. PMID 24757002 DOI: 10.1242/Dev.101048 |
0.382 |
|
| 2014 |
Cosson S, Lutolf MP. Hydrogel microfluidics for the patterning of pluripotent stem cells. Scientific Reports. 4: 4462. PMID 24662945 DOI: 10.1038/srep04462 |
0.302 |
|
| 2013 |
Mosiewicz KA, Kolb L, Van Der Vlies AJ, Martino MM, Lienemann PS, Hubbell JA, Ehrbar M, Lutolf MP. In situ cell manipulation through enzymatic hydrogel photopatterning Nature Materials. 12: 1072-1078. PMID 24121990 DOI: 10.1038/Nmat3766 |
0.519 |
|
| 2013 |
Cosson S, Allazetta S, Lutolf MP. Patterning of cell-instructive hydrogels by hydrodynamic flow focusing. Lab On a Chip. 13: 2099-105. PMID 23598796 DOI: 10.1039/c3lc50219h |
0.327 |
|
| 2013 |
Martino MM, Briquez PS, Ranga A, Lutolf MP, Hubbell JA. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix Proceedings of the National Academy of Sciences of the United States of America. 110: 4563-4568. PMID 23487783 DOI: 10.1073/Pnas.1221602110 |
0.425 |
|
| 2012 |
Larsson HM, Lee ST, Roccio M, Velluto D, Lutolf MP, Frey P, Hubbell JA. Sorting live stem cells based on Sox2 mRNA expression. Plos One. 7: e49874. PMID 23209609 DOI: 10.1371/Journal.Pone.0049874 |
0.467 |
|
| 2011 |
Sala A, Hänseler P, Ranga A, Lutolf MP, Vörös J, Ehrbar M, Weber FE. Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 1102-11. PMID 21986771 DOI: 10.1039/c1ib00045d |
0.385 |
|
| 2010 |
Bott K, Upton Z, Schrobback K, Ehrbar M, Hubbell JA, Lutolf MP, Rizzi SC. The effect of matrix characteristics on fibroblast proliferation in 3D gels. Biomaterials. 31: 8454-64. PMID 20684983 DOI: 10.1016/J.Biomaterials.2010.07.046 |
0.508 |
|
| 2010 |
Mosiewicz KA, Johnsson K, Lutolf MP. Phosphopantetheinyl transferase-catalyzed formation of bioactive hydrogels for tissue engineering. Journal of the American Chemical Society. 132: 5972-4. PMID 20373804 DOI: 10.1021/Ja9098164 |
0.336 |
|
| 2010 |
Jo YS, Rizzi SC, Ehrbar M, Weber FE, Hubbell JA, Lutolf MP. Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides. Journal of Biomedical Materials Research. Part A. 93: 870-7. PMID 19701911 DOI: 10.1002/Jbm.A.32580 |
0.435 |
|
| 2009 |
Lutolf MP. Integration column: artificial ECM: expanding the cell biology toolbox in 3D. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 235-41. PMID 20023734 DOI: 10.1039/b902243k |
0.326 |
|
| 2009 |
Lutolf MP, Gilbert PM, Blau HM. Designing materials to direct stem-cell fate. Nature. 462: 433-41. PMID 19940913 DOI: 10.1038/Nature08602 |
0.316 |
|
| 2009 |
Jo YS, Gantz J, Hubbell JA, Lutolf MP. Tailoring hydrogel degradation and drug release via neighboring amino acid controlled ester hydrolysis Soft Matter. 5: 440-446. DOI: 10.1039/B814584A |
0.418 |
|
| 2008 |
Cordey M, Limacher M, Kobel S, Taylor V, Lutolf MP. Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays. Stem Cells (Dayton, Ohio). 26: 2586-94. PMID 18669905 DOI: 10.1634/stemcells.2008-0498 |
0.306 |
|
| 2008 |
Kraehenbuehl TP, Zammaretti P, Van der Vlies AJ, Schoenmakers RG, Lutolf MP, Jaconi ME, Hubbell JA. Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel Biomaterials. 29: 2757-2766. PMID 18396331 DOI: 10.1016/J.Biomaterials.2008.03.016 |
0.496 |
|
| 2008 |
Raeber GP, Lutolf MP, Hubbell JA. Part II: Fibroblasts preferentially migrate in the direction of principal strain Biomechanics and Modeling in Mechanobiology. 7: 215-225. PMID 17619206 DOI: 10.1007/S10237-007-0090-1 |
0.403 |
|
| 2008 |
Ehrbar M, Lütolf MP, Rizzi SC, Hubbell JA, Weber FE. Artificial extracellular matrices for bone tissue engineering Bone. 42: S72. DOI: 10.1016/J.Bone.2007.12.131 |
0.396 |
|
| 2007 |
Ehrbar M, Rizzi SC, Schoenmakers RG, Miguel BS, Hubbell JA, Weber FE, Lutolf MP. Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. Biomacromolecules. 8: 3000-7. PMID 17883273 DOI: 10.1021/Bm070228F |
0.496 |
|
| 2007 |
Raeber GP, Lutolf MP, Hubbell JA. Mechanisms of 3-D migration and matrix remodeling of fibroblasts within artificial ECMs Acta Biomaterialia. 3: 615-629. PMID 17572164 DOI: 10.1016/J.Actbio.2007.03.013 |
0.517 |
|
| 2007 |
Ehrbar M, Rizzi SC, Hlushchuk R, Djonov V, Zisch AH, Hubbell JA, Weber FE, Lutolf MP. Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering Biomaterials. 28: 3856-3866. PMID 17568666 DOI: 10.1016/J.Biomaterials.2007.03.027 |
0.538 |
|
| 2005 |
Raeber GP, Lutolf MP, Hubbell JA. Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration. Biophysical Journal. 89: 1374-88. PMID 15923238 DOI: 10.1529/Biophysj.104.050682 |
0.463 |
|
| 2005 |
Lutolf MP, Hubbell JA. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nature Biotechnology. 23: 47-55. PMID 15637621 DOI: 10.1038/Nbt1055 |
0.55 |
|
| 2005 |
Fittkau MH, Zilla P, Bezuidenhout D, Lutolf MP, Human P, Hubbell JA, Davies N. The selective modulation of endothelial cell mobility on RGD peptide containing surfaces by YIGSR peptides Biomaterials. 26: 167-174. PMID 15207463 DOI: 10.1016/J.Biomaterials.2004.02.012 |
0.439 |
|
| 2004 |
Park Y, Lutolf MP, Hubbell JA, Hunziker EB, Wong M. Bovine primary chondrocyte culture in synthetic matrix metalloproteinase-sensitive poly(ethylene glycol)-based hydrogels as a scaffold for cartilage repair. Tissue Engineering. 10: 515-22. PMID 15165468 DOI: 10.1089/107632704323061870 |
0.456 |
|
| 2004 |
Zisch AH, Lutolf MP, Hubbell JA. Biopolymeric delivery matrices for angiogenic growth factors. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 12: 295-310. PMID 14630296 DOI: 10.1016/S1054-8807(03)00089-9 |
0.471 |
|
| 2004 |
Lutolf MP, Hubbell JA. Synthesis and physicochemical characterization of end-linked poly(ethylene glycol)-co-peptide hydrogels formed by Michael-type addition. Biomacromolecules. 4: 713-22. PMID 12741789 DOI: 10.1021/Bm025744E |
0.404 |
|
| 2003 |
Zisch AH, Lutolf MP, Ehrbar M, Raeber GP, Rizzi SC, Davies N, Schmökel H, Bezuidenhout D, Djonov V, Zilla P, Hubbell JA. Cell-demanded release of VEGF from synthetic, biointeractive cell ingrowth matrices for vascularized tissue growth Faseb Journal. 17: 2260-2262. PMID 14563693 DOI: 10.1096/Fj.02-1041Fje |
0.486 |
|
| 2003 |
Lutolf MP, Weber FE, Schmoekel HG, Schense JC, Kohler T, Müller R, Hubbell JA. Repair of bone defects using synthetic mimetics of collagenous extracellular matrices. Nature Biotechnology. 21: 513-8. PMID 12704396 DOI: 10.1038/Nbt818 |
0.459 |
|
| 2003 |
Lutolf MP, Lauer-Fields JL, Schmoekel HG, Metters AT, Weber FE, Fields GB, Hubbell JA. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proceedings of the National Academy of Sciences of the United States of America. 100: 5413-8. PMID 12686696 DOI: 10.1073/Pnas.0737381100 |
0.492 |
|
| 2003 |
Lutolf M, Raeber G, Zisch A, Tirelli N, Hubbell J. Cell-Responsive Synthetic Hydrogels Advanced Materials. 15: 888-892. DOI: 10.1002/Adma.200304621 |
0.49 |
|
| 2002 |
Tirelli N, Lutolf MP, Napoli A, Hubbell JA. Poly(ethylene glycol) block copolymers. Journal of Biotechnology. 90: 3-15. PMID 12069046 DOI: 10.1016/S1389-0352(01)00057-5 |
0.405 |
|
| 2001 |
Lutolf MP, Tirelli N, Cerritelli S, Cavalli L, Hubbell JA. Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. Bioconjugate Chemistry. 12: 1051-6. PMID 11716699 DOI: 10.1021/Bc015519E |
0.367 |
|
| 2001 |
Elbert DL, Pratt AB, Lutolf MP, Halstenberg S, Hubbell JA. Protein delivery from materials formed by self-selective conjugate addition reactions. Journal of Controlled Release : Official Journal of the Controlled Release Society. 76: 11-25. PMID 11532309 DOI: 10.1016/S0168-3659(01)00398-4 |
0.646 |
|
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