| Year |
Citation |
Score |
| 2023 |
Lander VE, DeNardo DG. Pancreatic Cancer's PD1-roadblock: When T-cell reinvigoration is not enough. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 38038687 DOI: 10.1158/1078-0432.CCR-23-2991 |
0.365 |
|
| 2023 |
Storrs EP, Chati P, Usmani A, Sloan I, Krasnick BA, Babbra R, Harris PK, Sachs CM, Qaium F, Chatterjee D, Wetzel C, Goedegebuure SP, Hollander T, Anthony H, Ponce J, ... ... Denardo DG, et al. High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival. Npj Precision Oncology. 7: 105. PMID 37857854 DOI: 10.1038/s41698-023-00455-z |
0.385 |
|
| 2023 |
Baer JM, Zuo C, Kang LI, de la Lastra AA, Borcherding NC, Knolhoff BL, Bogner SJ, Zhu Y, Yang L, Laurent J, Lewis MA, Zhang N, Kim KW, Fields RC, Yokoyama WM, ... ... DeNardo DG, et al. Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC. Nature Immunology. PMID 37563309 DOI: 10.1038/s41590-023-01579-x |
0.363 |
|
| 2023 |
Herzog BH, Baer JM, Borcherding N, Kingston NL, Belle JI, Knolhoff BL, Hogg GD, Ahmad F, Kang LI, Petrone J, Lin CY, Govindan R, DeNardo DG. Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non-small cell lung cancer. Science Translational Medicine. 15: eadh8005. PMID 37285399 DOI: 10.1126/scitranslmed.adh8005 |
0.484 |
|
| 2023 |
Liu X, Hogg GD, Zuo C, Borcherding NC, Baer JM, Lander VE, Kang LI, Knolhoff BL, Ahmad F, Osterhout RE, Galkin AV, Bruey JM, Carter LL, Mpoy C, Vij KR, ... ... DeNardo DG, et al. Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity. Cancer Cell. PMID 37236195 DOI: 10.1016/j.ccell.2023.04.018 |
0.46 |
|
| 2023 |
James CA, Baer JM, Zuo C, Panni UY, Knolhoff BL, Hogg GD, Kingston NL, Kang LI, Lander VE, Luo J, Tao Y, Watson MA, Aft R, Fields RC, Hawkins WG, ... DeNardo DG, et al. Systemic Alterations in Type-2 Conventional Dendritic Cells Leads to Impaired Tumor Immunity in Pancreatic Cancer. Cancer Immunology Research. PMID 37229629 DOI: 10.1158/2326-6066.CIR-21-0946 |
0.436 |
|
| 2023 |
Panni UY, Chen MY, Zhang F, Cullinan DR, Li L, James CA, Zhang X, Rogers S, Alarcon A, Baer JM, Zhang D, Gao F, Miller CA, Gong Q, Lim KH, ... DeNardo DG, et al. Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology. Cancer Immunology, Immunotherapy : Cii. PMID 37179276 DOI: 10.1007/s00262-023-03463-x |
0.44 |
|
| 2023 |
Selli ME, Landmann J, Terekhova M, Lattin J, Heard A, Hsu YS, Chang TC, Chang JF, Warrington JM, Ha H, Kingston NL, Hogg G, Slade M, Berrien-Elliott MM, Foster M, ... ... DeNardo D, et al. Costimulatory domains direct distinct fates of CAR-driven T cell dysfunction. Blood. PMID 37130030 DOI: 10.1182/blood.2023020100 |
0.315 |
|
| 2023 |
Zuo C, Baer JM, Knolhoff BL, Belle JI, Liu X, Alarcon De La Lastra A, Fu C, Hogg GD, Kingston NL, Breden MA, Dodhiawala PB, Zhou DC, Lander VE, James CA, Ding L, ... ... DeNardo DG, et al. Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy. The Journal of Experimental Medicine. 220. PMID 36951731 DOI: 10.1084/jem.20212062 |
0.465 |
|
| 2023 |
Faget DV, Luo X, Inkman MJ, Ren Q, Su X, Ding K, Waters MR, Raut GK, Pandey G, Dodhiawala PB, Ramalho-Oliveira R, Ye J, Cole T, Murali B, Zheleznyak A, ... ... DeNardo DG, et al. p38MAPKa stromal reprogramming sensitizes metastatic breast cancer to immunotherapy. Cancer Discovery. PMID 36883955 DOI: 10.1158/2159-8290.CD-22-0907 |
0.432 |
|
| 2022 |
Peng H, Li L, Zuo C, Chen MY, Zhang X, Myers NB, Hogg GD, DeNardo DG, Goedegebuure SP, Hawkins WG, Gillanders WE. Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer. Frontiers in Immunology. 13: 1039226. PMID 36569934 DOI: 10.3389/fimmu.2022.1039226 |
0.301 |
|
| 2022 |
Lander VE, Belle JI, Kingston NL, Herndon JM, Hogg GD, Liu X, Kang LI, Knolhoff BL, Bogner SJ, Baer JM, Zuo C, Borcherding NC, Lander DP, Mpoy C, Scott J, ... ... DeNardo DG, et al. Stromal reprogramming by FAK inhibition overcomes radiation resistance to allow for immune priming and response to checkpoint blockade. Cancer Discovery. PMID 36165893 DOI: 10.1158/2159-8290.CD-22-0192 |
0.482 |
|
| 2022 |
Cui Zhou D, Jayasinghe RG, Chen S, Herndon JM, Iglesia MD, Navale P, Wendl MC, Caravan W, Sato K, Storrs E, Mo CK, Liu J, Southard-Smith AN, Wu Y, Naser Al Deen N, ... ... DeNardo DG, et al. Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer. Nature Genetics. PMID 35995947 DOI: 10.1038/s41588-022-01157-1 |
0.452 |
|
| 2022 |
Messex JK, Adams KLA, Hawkins WG, DeNardo D, Bardeesy N, Billadeau DD, Liou GY. Oncogenic Kras-Mediated Cytokine CCL15 Regulates Pancreatic Cancer Cell Migration and Invasion through ROS. Cancers. 14. PMID 35565279 DOI: 10.3390/cancers14092153 |
0.357 |
|
| 2022 |
Somani V, Zhang D, Dodhiawala PB, Lander VE, Liu X, Kang LI, Chen HP, Knolhoff BL, Li L, Grierson PM, Ruzinova MB, DeNardo DG, Lim KH. IRAK4 signaling drives resistance to checkpoint immunotherapy in pancreatic ductal adenocarcinoma. Gastroenterology. PMID 35271824 DOI: 10.1053/j.gastro.2022.02.035 |
0.469 |
|
| 2021 |
Ray A, Callaway MK, Rodríguez-Merced NJ, Crampton AL, Carlson M, Emme KB, Ensminger EA, Kinne AA, Schrope JH, Rasmussen HR, Jiang H, DeNardo DG, Wood DK, Provenzano PP. Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma. Jci Insight. PMID 34914633 DOI: 10.1172/jci.insight.150330 |
0.32 |
|
| 2021 |
Su X, Xu Y, Fox GC, Xiang J, Kwakwa KA, Davis JL, Belle JI, Lee WC, Wong WH, Fontana F, Hernandez-Aya L, Kobayashi T, Tomasson HM, Su J, Bakewell SJ, ... ... DeNardo DG, et al. Breast cancer derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment. The Journal of Clinical Investigation. PMID 34520398 DOI: 10.1172/JCI145296 |
0.539 |
|
| 2021 |
DeNardo DG, Galkin A, Dupont J, Zhou L, Bendell J. GB1275, a first-in-class CD11b modulator: rationale for immunotherapeutic combinations in solid tumors. Journal For Immunotherapy of Cancer. 9. PMID 34452928 DOI: 10.1136/jitc-2021-003005 |
0.554 |
|
| 2021 |
Uzhachenko RV, Bharti V, Ouyang Z, Blevins A, Mont S, Saleh N, Lawrence HA, Shen C, Chen SC, Ayers GD, DeNardo DG, Arteaga C, Richmond A, Vilgelm AE. Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors. Cell Reports. 35: 109271. PMID 34161761 DOI: 10.1016/j.celrep.2021.109271 |
0.409 |
|
| 2021 |
Uzhachenko RV, Bharti V, Ouyang Z, Blevins A, Mont S, Saleh N, Lawrence HA, Shen C, Chen SC, Ayers GD, DeNardo DG, Arteaga C, Richmond A, Vilgelm AE. Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors. Cell Reports. 35: 108944. PMID 33826903 DOI: 10.1016/j.celrep.2021.108944 |
0.513 |
|
| 2021 |
Liu X, Hogg GD, DeNardo DG. Rethinking immune checkpoint blockade: 'Beyond the T cell'. Journal For Immunotherapy of Cancer. 9. PMID 33468555 DOI: 10.1136/jitc-2020-001460 |
0.404 |
|
| 2020 |
Krisnawan VE, Stanley JA, Schwarz JK, DeNardo DG. Tumor Microenvironment as a Regulator of Radiation Therapy: New Insights into Stromal-Mediated Radioresistance. Cancers. 12. PMID 33050580 DOI: 10.3390/cancers12102916 |
0.314 |
|
| 2020 |
Wang S, Raybuck A, Shiuan E, Cho SH, Wang Q, Brantley-Sieders DM, Edwards D, Allaman MM, Nathan J, Wilson KT, DeNardo D, Zhang S, Cook R, Boothby M, Chen J. Selective inhibition of mTORC1 in tumor vessels increases antitumor immunity. Jci Insight. 5. PMID 32759497 DOI: 10.1172/Jci.Insight.139237 |
0.563 |
|
| 2020 |
Geraghty T, Rajagopalan A, Aslam R, Pohlman A, Venkatesh I, Zloza A, Cimbaluk D, DeNardo DG, Gupta V. Positive Allosteric Modulation of CD11b as a Novel Therapeutic Strategy Against Lung Cancer. Frontiers in Oncology. 10: 748. PMID 32528880 DOI: 10.3389/Fonc.2020.00748 |
0.538 |
|
| 2020 |
Hegde S, Krisnawan VE, Herzog BH, Zuo C, Breden MA, Knolhoff BL, Hogg GD, Tang JP, Baer JM, Mpoy C, Lee KB, Alexander KA, Rogers BE, Murphy KM, Hawkins WG, ... ... DeNardo DG, et al. Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer. Cancer Cell. 37: 289-307.e9. PMID 32183949 DOI: 10.1016/J.Ccell.2020.02.008 |
0.78 |
|
| 2020 |
González IA, Kang LI, Williams GA, Liu J, DeNardo DG, Hawkins WG, Chatterjee D. Tumor-Insular Complex in Neoadjuvant Treated Pancreatic Ductal Adenocarcinoma Is Associated With Higher Residual Tumor. The American Journal of Surgical Pathology. PMID 32091434 DOI: 10.1097/PAS.0000000000001454 |
0.38 |
|
| 2020 |
Mirlekar B, Michaud D, Lee SJ, Kren NP, Harris C, Greene K, Goldman EC, Gupta GP, Fields RC, Hawkins WG, DeNardo DG, Rashid NU, Yeh JJ, McRee AJ, Vincent BG, et al. B cell-Derived IL35 Drives STAT3-Dependent CD8 T-cell Exclusion in Pancreatic Cancer. Cancer Immunology Research. PMID 32024640 DOI: 10.1158/2326-6066.CIR-19-0349 |
0.31 |
|
| 2020 |
Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, et al. A framework for advancing our understanding of cancer-associated fibroblasts. Nature Reviews. Cancer. PMID 31980749 DOI: 10.1038/S41568-019-0238-1 |
0.545 |
|
| 2019 |
Li Q, Chen Y, Zhang D, Grossman J, Li L, Khurana N, Jiang H, Grierson P, Herndon J, DeNardo DG, Challen GA, Liu J, Ruzinova MB, Fields RC, Lim KH. IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colon cancer. Jci Insight. PMID 31527315 DOI: 10.1172/Jci.Insight.130867 |
0.403 |
|
| 2019 |
Volk-Draper L, Patel R, Bhattarai N, Yang J, Wilber A, DeNardo D, Ran S. Myeloid-Derived Lymphatic Endothelial Cell Progenitors Significantly Contribute to Lymphatic Metastasis in Clinical Breast Cancer. The American Journal of Pathology. PMID 31421071 DOI: 10.1016/J.Ajpath.2019.07.006 |
0.389 |
|
| 2019 |
Strand MS, Krasnick BA, Pan H, Zhang X, Bi Y, Brooks C, Wetzel C, Sankpal N, Fleming T, Goedegebuure SP, DeNardo DG, Gillanders WE, Hawkins WG, Wickline SA, Fields RC. Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles. Oncotarget. 10: 4761-4775. PMID 31413817 DOI: 10.18632/Oncotarget.27109 |
0.407 |
|
| 2019 |
Belle JI, DeNardo DG. A Single-Cell Window into Pancreas Cancer Fibroblast Heterogeneity. Cancer Discovery. 9: 1001-1002. PMID 31371323 DOI: 10.1158/2159-8290.CD-19-0576 |
0.454 |
|
| 2019 |
Bedognetti D, Ceccarelli M, Galluzzi L, Lu R, Palucka K, Samayoa J, Spranger S, Warren S, Wong KK, Ziv E, Chowell D, Coussens LM, De Carvalho DD, DeNardo DG, Galon J, et al. Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop. Journal For Immunotherapy of Cancer. 7: 167. PMID 31272507 DOI: 10.1186/S40425-019-0640-Y |
0.55 |
|
| 2019 |
Panni RZ, Herndon JM, Zuo C, Hegde S, Hogg GD, Knolhoff BL, Breden MA, Li X, Krisnawan VE, Khan SQ, Schwarz JK, Rogers BE, Fields RC, Hawkins WG, Gupta V, ... DeNardo DG, et al. Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies. Science Translational Medicine. 11. PMID 31270275 DOI: 10.1126/Scitranslmed.Aau9240 |
0.786 |
|
| 2019 |
Bedognetti D, Ceccarelli M, Galluzzi L, Lu R, Palucka K, Samayoa J, Spranger S, Warren S, Wong KK, Ziv E, Chowell D, Coussens LM, De Carvalho DD, DeNardo DG, Galon J, et al. Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop. Journal For Immunotherapy of Cancer. 7: 131. PMID 31113486 DOI: 10.1186/S40425-019-0602-4 |
0.639 |
|
| 2019 |
Jiang H, Liu X, Knolhoff BL, Hegde S, Lee KB, Jiang H, Fields RC, Pachter JA, Lim KH, DeNardo DG. Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion. Gut. PMID 31076405 DOI: 10.1136/gutjnl-2018-317424 |
0.704 |
|
| 2019 |
DeNardo DG, Ruffell B. Macrophages as regulators of tumour immunity and immunotherapy. Nature Reviews. Immunology. PMID 30718830 DOI: 10.1038/s41577-019-0127-6 |
0.404 |
|
| 2018 |
Grossman JG, Nywening TM, Belt BA, Panni RZ, Krasnick BA, DeNardo DG, Hawkins WG, Goedegebuure SP, Linehan DC, Fields RC. Recruitment of CCR2 tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer. Oncoimmunology. 7: e1470729. PMID 30228938 DOI: 10.1080/2162402X.2018.1470729 |
0.525 |
|
| 2018 |
Meyer MA, DeNardo DG. Better Together: B7S1 Checkpoint Blockade Synergizes with anti-PD1. Immunity. 48: 621-623. PMID 29669244 DOI: 10.1016/j.immuni.2018.03.029 |
0.391 |
|
| 2018 |
Meyer MA, Baer JM, Knolhoff BL, Nywening TM, Panni RZ, Su X, Weilbaecher KN, Hawkins WG, Ma C, Fields RC, Linehan DC, Challen GA, Faccio R, Aft RL, DeNardo DG. Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance. Nature Communications. 9: 1250. PMID 29593283 DOI: 10.1038/s41467-018-03600-6 |
0.588 |
|
| 2018 |
Brenot A, Knolhoff BL, DeNardo DG, Longmore GD. SNAIL1 action in tumor cells influences macrophage polarization and metastasis in breast cancer through altered GM-CSF secretion. Oncogenesis. 7: 32. PMID 29593211 DOI: 10.1038/s41389-018-0042-x |
0.49 |
|
| 2017 |
Nywening TM, Belt BA, Cullinan DR, Panni RZ, Han BJ, Sanford DE, Jacobs RC, Ye J, Patel AA, Gillanders WE, Fields RC, DeNardo DG, Hawkins WG, Goedegebuure P, Linehan DC. Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma. Gut. PMID 29196437 DOI: 10.1136/gutjnl-2017-313738 |
0.361 |
|
| 2017 |
Zhu Y, Herndon JM, Sojka DK, Kim KW, Knolhoff BL, Zuo C, Cullinan DR, Luo J, Bearden AR, Lavine KJ, Yokoyama WM, Hawkins WG, Fields RC, Randolph GJ, DeNardo DG. Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression. Immunity. 47: 597. PMID 28930665 DOI: 10.1016/j.immuni.2017.08.018 |
0.421 |
|
| 2017 |
Zhu Y, Herndon JM, Sojka DK, Kim KW, Knolhoff BL, Zuo C, Cullinan DR, Luo J, Bearden AR, Lavine KJ, Yokoyama WM, Hawkins WG, Fields RC, Randolph GJ, DeNardo DG. Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression. Immunity. 47: 323-338.e6. PMID 28813661 DOI: 10.1016/J.Immuni.2017.07.014 |
0.484 |
|
| 2017 |
Jiang H, Hegde S, DeNardo DG. Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy. Cancer Immunology, Immunotherapy : Cii. PMID 28451791 DOI: 10.1007/s00262-017-2003-1 |
0.78 |
|
| 2016 |
Jiang H, Hegde S, Knolhoff BL, Zhu Y, Herndon JM, Meyer MA, Nywening TM, Hawkins WG, Shapiro IM, Weaver DT, Pachter JA, Wang-Gillam A, DeNardo DG. Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy. Nature Medicine. PMID 27376576 DOI: 10.1038/Nm.4123 |
0.783 |
|
| 2016 |
Ruhland MK, Loza AJ, Capietto AH, Luo X, Knolhoff BL, Flanagan KC, Belt BA, Alspach E, Leahy K, Luo J, Schaffer A, Edwards JR, Longmore G, Faccio R, DeNardo DG, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nature Communications. 7: 11762. PMID 27272654 DOI: 10.1038/Ncomms11762 |
0.404 |
|
| 2016 |
Corsa CA, Brenot A, Grither WR, Van Hove S, Loza AJ, Zhang K, Ponik SM, Liu Y, DeNardo DG, Eliceiri KW, Keely PJ, Longmore GD. The Action of Discoidin Domain Receptor 2 in Basal Tumor Cells and Stromal Cancer-Associated Fibroblasts Is Critical for Breast Cancer Metastasis. Cell Reports. PMID 27264173 DOI: 10.1016/J.Celrep.2016.05.033 |
0.519 |
|
| 2016 |
Ohman KA, Hashim YM, Vangveravong S, Nywening TM, Cullinan DR, Goedegebuure SP, Liu J, Van Tine BA, Tiriac H, Tuveson DA, DeNardo DG, Spitzer D, Mach RH, Hawkins WG. Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic. Oncotarget. PMID 27244881 DOI: 10.18632/Oncotarget.9551 |
0.367 |
|
| 2016 |
Su X, Esser AK, Amend SR, Xiang J, Xu Y, Ross MH, Fox GC, Kobayashi T, Steri V, Roomp K, Francesca F, Hurchla MA, Knolhoff BL, Meyer MA, Morgan EA, ... ... DeNardo D, et al. Antagonizing integrin beta3 increases immune suppression in cancer. Cancer Research. PMID 27216180 DOI: 10.1158/0008-5472.Can-15-2663 |
0.383 |
|
| 2016 |
Nywening TM, Wang-Gillam A, Sanford DE, Belt BA, Panni RZ, Cusworth BM, Toriola AT, Nieman RK, Worley LA, Yano M, Fowler KJ, Lockhart AC, Suresh R, Tan BR, Lim KH, ... ... DeNardo DG, et al. Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial. The Lancet. Oncology. PMID 27055731 DOI: 10.1016/S1470-2045(16)00078-4 |
0.304 |
|
| 2016 |
D'Amico L, Mahajan S, Capietto AH, Yang Z, Zamani A, Ricci B, Bumpass DB, Meyer M, Su X, Wang-Gillam A, Weilbaecher K, Stewart SA, DeNardo DG, Faccio R. Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer. The Journal of Experimental Medicine. PMID 27045006 DOI: 10.1084/Jem.20150950 |
0.504 |
|
| 2016 |
Demehri S, Cunningham TJ, Manivasagam S, Ngo KH, Moradi Tuchayi S, Reddy R, Meyers MA, DeNardo DG, Yokoyama WM. Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis. The Journal of Clinical Investigation. PMID 26927668 DOI: 10.1172/Jci83724 |
0.472 |
|
| 2015 |
Zhu Y, Hawkins WG, DeNardo DG. Regramming myeloid responses to improve cancer immunotherapy. Oncoimmunology. 4: e974399. PMID 26155432 DOI: 10.4161/2162402X.2014.974399 |
0.495 |
|
| 2015 |
Shiao SL, Ruffell B, DeNardo DG, Faddegon BA, Park CC, Coussens LM. TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy. Cancer Immunology Research. 3: 518-25. PMID 25716473 DOI: 10.1158/2326-6066.CIR-14-0232 |
0.658 |
|
| 2014 |
Volk-Draper L, Hall K, Griggs C, Rajput S, Kohio P, DeNardo D, Ran S. Paclitaxel therapy promotes breast cancer metastasis in a TLR4-dependent manner. Cancer Research. 74: 5421-34. PMID 25274031 DOI: 10.1158/0008-5472.Can-14-0067 |
0.51 |
|
| 2014 |
Zhu Y, Knolhoff BL, Meyer MA, Nywening TM, West BL, Luo J, Wang-Gillam A, Goedegebuure SP, Linehan DC, DeNardo DG. CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Research. 74: 5057-69. PMID 25082815 DOI: 10.1158/0008-5472.CAN-13-3723 |
0.609 |
|
| 2014 |
Panni RZ, Sanford DE, Belt BA, Mitchem JB, Worley LA, Goetz BD, Mukherjee P, Wang-Gillam A, Link DC, Denardo DG, Goedegebuure SP, Linehan DC. Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer. Cancer Immunology, Immunotherapy : Cii. 63: 513-28. PMID 24652403 DOI: 10.1007/S00262-014-1527-X |
0.479 |
|
| 2013 |
Zhong H, Sanchez C, Spitrzer D, Plambeck-Suess S, Gibbs J, Hawkins WG, Denardo D, Gao F, Pufahl RA, Lockhart AC, Xu M, Linehan D, Weber J, Wang-Gillam A. Synergistic effects of concurrent blockade of PI3K and MEK pathways in pancreatic cancer preclinical models. Plos One. 8: e77243. PMID 24130864 DOI: 10.1371/Journal.Pone.0077243 |
0.353 |
|
| 2013 |
Panni RZ, Linehan DC, Denardo DG. Targeting tumor-infiltrating macrophages to combat cancer Immunotherapy. 5: 1075-1087. PMID 24088077 DOI: 10.2217/imt.13.102 |
0.506 |
|
| 2013 |
Ruffell B, Affara NI, Cottone L, Junankar S, Johansson M, DeNardo DG, Korets L, Reinheckel T, Sloane BF, Bogyo M, Coussens LM. Cathepsin C is a tissue-specific regulator of squamous carcinogenesis. Genes & Development. 27: 2086-98. PMID 24065739 DOI: 10.1101/Gad.224899.113 |
0.617 |
|
| 2013 |
Mitchem JB, Brennan DJ, Knolhoff BL, Belt BA, Zhu Y, Sanford DE, Belaygorod L, Carpenter D, Collins L, Piwnica-Worms D, Hewitt S, Udupi GM, Gallagher WM, Wegner C, West BL, ... ... DeNardo DG, et al. Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses. Cancer Research. 73: 1128-41. PMID 23221383 DOI: 10.1158/0008-5472.Can-12-2731 |
0.592 |
|
| 2012 |
Panni RZ, Linehan DC, DeNardo DG. Tumor-infiltrating macrophages, cancer stem cells and therapeutic responses Oncotarget. 3: 1497-1498. PMID 23455077 |
0.512 |
|
| 2012 |
Mitchem JB, DeNardo DG. Battle over CCL2 for control of the metastatic niche: neutrophils versus monocytes. Breast Cancer Research : Bcr. 14: 315. PMID 22809105 DOI: 10.1186/bcr3149 |
0.528 |
|
| 2011 |
DeNardo DG, Brennan DJ, Rexhepaj E, Ruffell B, Shiao SL, Madden SF, Gallagher WM, Wadhwani N, Keil SD, Junaid SA, Rugo HS, Hwang ES, Jirström K, West BL, Coussens LM. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discovery. 1: 54-67. PMID 22039576 DOI: 10.1158/2159-8274.CD-10-0028 |
0.689 |
|
| 2011 |
Daldrup-Link HE, Golovko D, Ruffell B, Denardo DG, Castaneda R, Ansari C, Rao J, Tikhomirov GA, Wendland MF, Corot C, Coussens LM. MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5695-704. PMID 21791632 DOI: 10.1158/1078-0432.Ccr-10-3420 |
0.557 |
|
| 2010 |
Ursini-Siegel J, Cory S, Zuo D, Hardy WR, Rexhepaj E, Lam S, Schade B, Jirstrom K, Bjur E, Piccirillo CA, Denardo D, Coussens LM, Brennan DJ, Gallagher WM, Park M, et al. Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response. Cancer Research. 70: 7776-87. PMID 20924104 DOI: 10.1158/0008-5472.Can-10-2229 |
0.719 |
|
| 2010 |
Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS. Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Research. 70: 7465-75. PMID 20841473 DOI: 10.1158/0008-5472.Can-10-1439 |
0.696 |
|
| 2010 |
DeNardo DG, Andreu P, Coussens LM. Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity. Cancer Metastasis Reviews. 29: 309-16. PMID 20405169 DOI: 10.1007/s10555-010-9223-6 |
0.734 |
|
| 2010 |
Andreu P, Johansson M, Affara NI, Pucci F, Tan T, Junankar S, Korets L, Lam J, Tawfik D, DeNardo DG, Naldini L, de Visser KE, De Palma M, Coussens LM. FcRgamma activation regulates inflammation-associated squamous carcinogenesis. Cancer Cell. 17: 121-34. PMID 20138013 DOI: 10.1016/J.Ccr.2009.12.019 |
0.633 |
|
| 2010 |
Ruffell B, DeNardo DG, Affara NI, Coussens LM. Lymphocytes in cancer development: polarization towards pro-tumor immunity. Cytokine & Growth Factor Reviews. 21: 3-10. PMID 20005150 DOI: 10.1016/j.cytogfr.2009.11.002 |
0.739 |
|
| 2009 |
Sista AK, Knebel RJ, Tavri S, Johansson M, DeNardo DG, Boddington SE, Kishore SA, Ansari C, Reinhart V, Coakley FV, Coussens LM, Daldrup-Link HE. Optical imaging of the peri-tumoral inflammatory response in breast cancer. Journal of Translational Medicine. 7: 94. PMID 19906309 DOI: 10.1186/1479-5876-7-94 |
0.646 |
|
| 2009 |
DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, Coussens LM. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell. 16: 91-102. PMID 19647220 DOI: 10.1016/j.ccr.2009.06.018 |
0.67 |
|
| 2008 |
DeNardo DG, Johansson M, Coussens LM. Inflaming gastrointestinal oncogenic programming. Cancer Cell. 14: 7-9. PMID 18598939 DOI: 10.1016/j.ccr.2008.06.010 |
0.582 |
|
| 2008 |
Johansson M, Denardo DG, Coussens LM. Polarized immune responses differentially regulate cancer development. Immunological Reviews. 222: 145-54. PMID 18363999 DOI: 10.1111/j.1600-065X.2008.00600.x |
0.708 |
|
| 2008 |
DeNardo DG, Johansson M, Coussens LM. Immune cells as mediators of solid tumor metastasis. Cancer Metastasis Reviews. 27: 11-8. PMID 18066650 DOI: 10.1007/s10555-007-9100-0 |
0.728 |
|
| 2007 |
DeNardo DG, Coussens LM. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Research : Bcr. 9: 212. PMID 17705880 DOI: 10.1186/bcr1746 |
0.703 |
|
| 2005 |
Kong G, Kim HT, Wu K, DeNardo D, Hilsenbeck SG, Xu XC, Lamph WW, Bissonnette R, Dannenberg AJ, Brown PH. The retinoid X receptor-selective retinoid, LGD1069, down-regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: implications for molecular-based chemoprevention. Cancer Research. 65: 3462-9. PMID 15833882 DOI: 10.1158/0008-5472.CAN-03-2912 |
0.304 |
|
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