Dario Melgari - Publications

Affiliations: 
University of Bristol, Bristol, England, United Kingdom 

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Frosio A, Micaglio E, Polsinelli I, Calamaio S, Melgari D, Prevostini R, Ghiroldi A, Binda A, Carrera P, Villa M, Mastrocinque F, Presi S, Salerno R, Boccellino A, Anastasia L, et al. Unravelling Novel Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights. International Journal of Molecular Sciences. 24. PMID 37894777 DOI: 10.3390/ijms242015089  0.336
2023 DiFrancesco JC, Ragona F, Murano C, Frosio A, Melgari D, Binda A, Calamaio S, Prevostini R, Mauri M, Canafoglia L, Castellotti B, Messina G, Gellera C, Previtali R, Veggiotti P, et al. A novel de novo HCN2 loss-of-function variant causing developmental and epileptic encephalopathy treated with a ketogenic diet. Epilepsia. 64: e222-e228. PMID 37746765 DOI: 10.1111/epi.17777  0.336
2022 Ghiroldi A, Ciconte G, Creo P, Tarantino A, Melgari D, D'Imperio S, Piccoli M, Cirillo F, Micaglio E, Monasky MM, Frosio A, Locati ET, Vicedomini G, Rivolta I, Pappone C, et al. Alterations of the Sialylation Machinery in Brugada Syndrome. International Journal of Molecular Sciences. 23. PMID 36361941 DOI: 10.3390/ijms232113154  0.303
2022 Melgari D, Frosio A, Calamaio S, Marzi GA, Pappone C, Rivolta I. T-Type Calcium Channels: A Mixed Blessing. International Journal of Molecular Sciences. 23. PMID 36077291 DOI: 10.3390/ijms23179894  0.335
2020 Melgari D, Barbier C, Dilanian G, Rücker-Martin C, Doisne N, Coulombe A, Hatem SN, Balse E. Microtubule polymerization state and clathrin-dependent internalization regulate dynamics of cardiac potassium channel: Microtubule and clathrin control of KV1.5 channel. Journal of Molecular and Cellular Cardiology. PMID 32445844 DOI: 10.1016/j.yjmcc.2020.05.004  0.412
2020 Beuriot A, Eichel CA, Dilanian G, Louault F, Melgari D, Doisne N, Coulombe A, Hatem SN, Balse E. Distinct Calcium/CAlmodulin-dependent Serine protein Kinase domains control cardiac sodium channel membrane expression and focal adhesion anchoring. Heart Rhythm. PMID 31904424 DOI: 10.1016/j.hrthm.2019.12.019  0.337
2019 Lei CL, Clerx M, Beattie KA, Melgari D, Hancox JC, Gavaghan DJ, Polonchuk L, Wang K, Mirams GR. Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence. Biophysical Journal. PMID 31451180 DOI: 10.1016/J.Bpj.2019.07.030  0.547
2018 Hancox J, El Harchi A, Melgari D, Zhang H. Investigation of hERG1b influence on hERG channel pharmacology at physiological temperature Journal of Pharmacology and Pharmacotherapeutics. 9: 92. DOI: 10.4103/Jpp.Jpp_158_17  0.59
2016 Melgari D, Ng GA, Hancox JC. Letter by Melgari et al Regarding Article, "Ivabradine: Role in the Chronic Heart Failure Armamentarium". Circulation. 134: e296-7. PMID 27672201 DOI: 10.1161/Circulationaha.116.023752  0.441
2016 Beattie K, Melgari D, Hancox J, Mirams G. Exploring temperature-dependence of hERG channel kinetics using sine wave voltage protocols Journal of Pharmacological and Toxicological Methods. 81: 339-340. DOI: 10.1016/J.Vascn.2016.02.017  0.587
2015 Hancox JC, Melgari D, Dempsey CE, Brack KE, Mitcheson J, Ng GA. hERG potassium channel inhibition by ivabradine may contribute to QT prolongation and risk of torsades de pointes. Therapeutic Advances in Drug Safety. 6: 177-9. PMID 26301071 DOI: 10.1177/2042098615595546  0.553
2015 Melgari D, Brack KE, Zhang Y, El Harchi A, Mitcheson JS, Dempsey CE, Ng GA, Hancox JC. hERG potassium channel inhibition by ivabradine requires channel gating. Journal of Molecular and Cellular Cardiology. 87: 126-8. PMID 26275355 DOI: 10.1016/J.Yjmcc.2015.08.002  0.646
2015 Melgari D, Zhang Y, El Harchi A, Dempsey CE, Hancox JC. Molecular basis of hERG potassium channel blockade by the class Ic antiarrhythmic flecainide. Journal of Molecular and Cellular Cardiology. PMID 26159617 DOI: 10.1016/J.Yjmcc.2015.06.021  0.629
2015 Melgari D, Brack KE, Zhang C, Zhang Y, El Harchi A, Mitcheson JS, Dempsey CE, Ng GA, Hancox JC. hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine. Journal of the American Heart Association. 4. PMID 25911606 DOI: 10.1161/Jaha.115.001813  0.661
2015 Hancox JC, Melgari D, Dempsey CE, Brack KE, Mitcheson J, Ng GA. hERG potassium channel inhibition by ivabradine may contribute to QT prolongation and risk of torsades de pointes Therapeutic Advances in Drug Safety. 6: 177-179. DOI: 10.1177/2042098615595546  0.592
2015 Melgari D, Brack KE, Zhang Y, El Harchi A, Mitcheson JS, Dempsey CE, Ng GA, Hancox JC. HERG potassium channel inhibition by ivabradine requires channel gating Journal of Molecular and Cellular Cardiology. 87: 126-128. DOI: 10.1016/j.yjmcc.2015.08.002  0.629
2014 Melgari D, Du C, El Harchi A, Zhang Y, Hancox JC. Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration. Physiological Reports. 2. PMID 25318749 DOI: 10.14814/Phy2.12165  0.572
2014 Melgari D, El Harchi A, Dempsey CE, Hancox JC. Sensitivity of Flecainide Inhibition of hERG Channels to Channel Inactivation Biophysical Journal. 106: 138a. DOI: 10.1016/J.Bpj.2013.11.807  0.604
2013 El Harchi A, Melgari D, Hancox JC. Investigation of the Influence of hERG 1b on hERG Channel Pharmacology Biophysical Journal. 104: 297a. DOI: 10.1016/J.Bpj.2012.11.1655  0.588
2012 El Harchi A, Melgari D, Zhang YH, Zhang H, Hancox JC. Action Potential Clamp and Pharmacology of the Variant 1 Short QT Syndrome T618I hERG K+ Channel Plos One. 7. PMID 23300672 DOI: 10.1371/Journal.Pone.0052451  0.605
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