Juan Pablo Maianti - Publications

Chemistry Harvard University, Cambridge, MA, United States 

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Usanov DL, Chan AI, Maianti JP, Liu DR. Author Correction: Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules. Nature Chemistry. PMID 31576016 DOI: 10.1038/S41557-019-0360-4  0.628
2019 Maianti JP, Tan GA, Vetere A, Welsh AJ, Wagner BK, Seeliger MA, Liu DR. Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme. Nature Chemical Biology. PMID 31086331 DOI: 10.1038/S41589-019-0271-0  0.463
2018 Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR. Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction. Nature Biotechnology. PMID 29813047 DOI: 10.1038/Nbt.4172  0.333
2018 Kanazawa H, Saavedra OM, Maianti JP, Young SA, Izquierdo L, Smith TK, Hanessian S, Kondo J. Structure-Based Design of a Eukaryote-Selective Antiprotozoal Fluorinated Aminoglycoside. Chemmedchem. PMID 29766661 DOI: 10.1002/Cmdc.201800166  0.614
2018 Usanov DL, Chan AI, Maianti JP, Liu DR. Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules. Nature Chemistry. PMID 29610462 DOI: 10.1038/S41557-018-0033-8  0.66
2016 Maianti JP, Hanessian S. Structural hybridization of three aminoglycoside antibiotics yields a potent broad-spectrum bactericide that eludes bacterial resistance enzymes Medchemcomm. 7: 170-176. DOI: 10.1039/C5Md00429B  0.606
2014 Maianti JP, Kanazawa H, Dozzo P, Matias RD, Feeney LA, Armstrong ES, Hildebrandt DJ, Kane TR, Gliedt MJ, Goldblum AA, Linsell MS, Aggen JB, Kondo J, Hanessian S. Toxicity modulation, resistance enzyme evasion, and A-site X-ray structure of broad-spectrum antibacterial neomycin analogs. Acs Chemical Biology. 9: 2067-73. PMID 25019242 DOI: 10.1021/Cb5003416  0.592
2014 Maianti JP, McFedries A, Foda ZH, Kleiner RE, Du XQ, Leissring MA, Tang WJ, Charron MJ, Seeliger MA, Saghatelian A, Liu DR. Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. Nature. 511: 94-8. PMID 24847884 DOI: 10.1038/Nature13297  0.656
2014 Hanessian S, Saavedra OM, Vilchis-Reyes MA, Maianti JP, Kanazawa H, Dozzo P, Matias RD, Serio A, Kondo J. Synthesis, broad spectrum antibacterial activity, and X-ray co-crystal structure of the decoding bacterial ribosomal A-site with 4′-deoxy-4′-fluoro neomycin analogs Chemical Science. 5: 4621-4632. DOI: 10.1039/C4Sc01626B  0.618
2013 Kondo J, Koganei M, Maianti JP, Ly VL, Hanessian S. Crystal structures of a bioactive 6'-hydroxy variant of sisomicin bound to the bacterial and protozoal ribosomal decoding sites. Chemmedchem. 8: 733-9. PMID 23436717 DOI: 10.1002/Cmdc.201200579  0.664
2013 Kondo J, Koganei M, Maianti JP, Ly VL, Hanessian S. Back Cover: Crystal Structures of a Bioactive 6′-Hydroxy Variant of Sisomicin Bound to the Bacterial and Protozoal Ribosomal Decoding Sites (ChemMedChem 5/2013) Chemmedchem. 8: 864-864. DOI: 10.1002/Cmdc.201390019  0.653
2012 Hanessian S, Maianti JP, Ly VL, Deschênes-Simard B. Structural and kinetic study of self-assembling macrocyclic dimer natural product aminoglycoside 66-40C and unnatural variants Chemical Science. 3: 249-256. DOI: 10.1039/C1Sc00538C  0.636
2011 Hanessian S, Giguère A, Grzyb J, Maianti JP, Saavedra OM, Aggen JB, Linsell MS, Goldblum AA, Hildebrandt DJ, Kane TR, Dozzo P, Gliedt MJ, Matias RD, Feeney LA, Armstrong ES. Toward Overcoming Staphylococcus aureus Aminoglycoside Resistance Mechanisms with a Functionally Designed Neomycin Analogue. Acs Medicinal Chemistry Letters. 2: 924-8. PMID 24900282 DOI: 10.1021/Ml200202Y  0.529
2011 Hanessian S, Maianti JP, Matias RD, Feeney LA, Armstrong ES. Hybrid aminoglycoside antibiotics via Tsuji palladium-catalyzed allylic deoxygenation. Organic Letters. 13: 6476-9. PMID 22085292 DOI: 10.1021/Ol2027703  0.524
2010 Hanessian S, Maianti JP. Biomimetic synthesis and structural refinement of the macrocyclic dimer aminoglycoside 66-40C--the remarkably selective self-condensation of a putative aldehyde intermediate in the submerged culture medium producing sisomicin. Chemical Communications (Cambridge, England). 46: 2013-5. PMID 20221476 DOI: 10.1039/B925668G  0.592
2009 Hanessian S, Szychowski J, Maianti JP. Synthesis and comparative antibacterial activity of verdamicin C2 and C2a. A new oxidation of primary allylic azides in dihydro[2H]pyrans. Organic Letters. 11: 429-32. PMID 19072132 DOI: 10.1021/Ol802421D  0.486
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