J.G.C. van Hasselt - Publications

Affiliations: 
Leiden University, Leiden, Netherlands 
Area:
pharmacology, oncology, pediatrics, antibiotics, infectious diseases, modelling
Website:
http://pharmacology.leidenuniv.nl/people/vanhasselt

27/127 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yu H, Janssen JM, Sawicki E, van Hasselt JGC, de Weger VA, Nuijen B, Schellens JHM, Beijnen JH, Huitema ADR. A Population Pharmacokinetic Model of Oral Docetaxel Coadministered With Ritonavir to Support Early Clinical Development. Journal of Clinical Pharmacology. PMID 31595980 DOI: 10.1002/Jcph.1532  0.503
2017 Krekels EHJ, van Hasselt JGC, van den Anker JN, Allegaert K, Tibboel D, Knibbe CAJ. Evidence-based drug treatment for special patient populations through model-based approaches. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. S22-S26. PMID 28502674 DOI: 10.1016/j.ejps.2017.05.022  0.318
2016 Jacobs BA, Deenen MJ, Pluim D, van Hasselt JG, Krähenbühl MD, van Geel RM, de Vries N, Rosing H, Meulendijks D, Burylo AM, Cats A, Beijnen JH, Huitema AD, Schellens JH. Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers. British Journal of Clinical Pharmacology. PMID 27161955 DOI: 10.1111/Bcp.13007  0.684
2016 Meulendijks D, van Hasselt JG, Huitema AD, van Tinteren H, Deenen MJ, Beijnen JH, Cats A, Schellens JH. Renal function, body surface area, and age are associated with risk of early-onset fluoropyrimidine-associated toxicity in patients treated with capecitabine-based anticancer regimens in daily clinical care. European Journal of Cancer (Oxford, England : 1990). 54: 120-130. PMID 26761784 DOI: 10.1016/J.Ejca.2015.10.013  0.707
2015 van Hasselt J, Gupta A, Hussein Z, Beijnen JH, Schellens J, Huitema A. Disease Progression/Clinical Outcome Model for Castration-Resistant Prostate Cancer in Patients Treated With Eribulin. Cpt: Pharmacometrics & Systems Pharmacology. 4: 386-95. PMID 26312162 DOI: 10.1002/psp4.49  0.577
2015 van Hasselt J, Gupta A, Hussein Z, Beijnen JH, Schellens J, Huitema A. Integrated Simulation Framework for Toxicity, Dose Intensity, Disease Progression, and Cost Effectiveness for Castration-Resistant Prostate Cancer Treatment With Eribulin. Cpt: Pharmacometrics & Systems Pharmacology. 4: 374-85. PMID 26312161 DOI: 10.1002/psp4.48  0.607
2015 van Hasselt JG, Allegaert K, van Calsteren K, Beijnen JH, Schellens JH, Huitema AD. Corrigendum to "Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy". Biomed Research International. 2015: 124035. PMID 25922829 DOI: 10.1155/2015/124035  0.705
2015 Frederix GW, Severens JL, Hövels AM, van Hasselt JG, Hooiveld MJ, Neven P, Raaijmakers JA, Schellens JH. Real world cost of human epidermal receptor 2-positive metastatic breast cancer patients: a longitudinal incidence-based observational costing study in the Netherlands and Belgium. European Journal of Cancer Care. 24: 340-54. PMID 25413216 DOI: 10.1111/Ecc.12266  0.391
2015 Yu H, Steeghs N, Kloth JS, de Wit D, van Hasselt JG, van Erp NP, Beijnen JH, Schellens JH, Mathijssen RH, Huitema AD. Integrated semi-physiological pharmacokinetic model for both sunitinib and its active metabolite SU12662. British Journal of Clinical Pharmacology. 79: 809-19. PMID 25393890 DOI: 10.1111/Bcp.12550  0.724
2015 Van Hasselt JGC, Gupta A, Hussein Z, Beijnen JH, Schellens JHM, Huitema ADR. Disease Progression/Clinical Outcome Model for Castration-Resistant Prostate Cancer in Patients Treated with Eribulin Cpt: Pharmacometrics and Systems Pharmacology. 4: 386-395. DOI: 10.1002/psp4.49  0.448
2015 Van Hasselt JGC, Gupta A, Hussein Z, Beijnen JH, Schellens JHM, Huitema ADR. Integrated Simulation Framework for Toxicity, Dose Intensity, Disease Progression, and Cost Effectiveness for Castration-Resistant Prostate Cancer Treatment with Eribulin Cpt: Pharmacometrics and Systems Pharmacology. 4: 374-385. DOI: 10.1002/psp4.48  0.434
2014 van Hasselt JG, van Eijkelenburg NK, Beijnen JH, Schellens JH, Huitema AD. Design of a drug-drug interaction study of vincristine with azole antifungals in pediatric cancer patients using clinical trial simulation. Pediatric Blood & Cancer. 61: 2223-9. PMID 25175364 DOI: 10.1002/Pbc.25198  0.705
2014 van Hasselt JG, Schellens JH, Beijnen JH, Huitema AD. Design of informative renal impairment studies: evaluation of the impact of design stratification on bias, precision and dose adjustment error. Investigational New Drugs. 32: 913-27. PMID 24788562 DOI: 10.1007/S10637-014-0103-8  0.71
2014 van Hasselt JG, van Calsteren K, Heyns L, Han S, Mhallem Gziri M, Schellens JH, Beijnen JH, Huitema AD, Amant F. Optimizing anticancer drug treatment in pregnant cancer patients: pharmacokinetic analysis of gestation-induced changes for doxorubicin, epirubicin, docetaxel and paclitaxel. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 25: 2059-65. PMID 24713311 DOI: 10.1093/Annonc/Mdu140  0.58
2014 van Hasselt JG, Allegaert K, van Calsteren K, Beijnen JH, Schellens JH, Huitema AD. Semiphysiological versus empirical modelling of the population pharmacokinetics of free and total cefazolin during pregnancy. Biomed Research International. 2014: 897216. PMID 24672799 DOI: 10.1155/2014/897216  0.73
2014 Frederix GW, van Hasselt JG, Schellens JH, Hövels AM, Raaijmakers JA, Huitema AD, Severens JL. The impact of structural uncertainty on cost-effectiveness models for adjuvant endocrine breast cancer treatments: the need for disease-specific model standardization and improved guidance. Pharmacoeconomics. 32: 47-61. PMID 24263964 DOI: 10.1007/S40273-013-0106-X  0.692
2013 Frederix GW, Severens JL, Hövels AM, van Hasselt JG, Raaijmakers JA, Schellens JH. Time-dependent resource use and costs associated with different states of disease in patients diagnosed with HER-2-positive metastatic breast cancer. Breast Cancer Research and Treatment. 139: 489-95. PMID 23645005 DOI: 10.1007/S10549-013-2532-Z  0.384
2013 van Hasselt JG, Gupta A, Hussein Z, Beijnen JH, Schellens JH, Huitema AD. Population pharmacokinetic-pharmacodynamic analysis for eribulin mesilate-associated neutropenia. British Journal of Clinical Pharmacology. 76: 412-24. PMID 23601153 DOI: 10.1111/Bcp.12143  0.744
2013 van Hasselt JG, van Eijkelenburg NK, Huitema AD, Schellens JH, Schouten-van Meeteren AY. Severe skin toxicity in pediatric oncology patients treated with voriconazole and concomitant methotrexate. Antimicrobial Agents and Chemotherapy. 57: 2878-81. PMID 23571545 DOI: 10.1128/Aac.00068-13  0.671
2013 Frederix GW, van Hasselt JG, Severens JL, Hövels AM, Huitema AD, Raaijmakers JA, Schellens JH. Development of a framework for cohort simulation in cost-effectiveness analyses using a multistep ordinary differential equation solver algorithm in R. Medical Decision Making : An International Journal of the Society For Medical Decision Making. 33: 780-92. PMID 23515213 DOI: 10.1177/0272989X13476763  0.657
2013 Van Hasselt JGC, van Eijkelenburg NKA, Beijnen JH, Schellens JHM, Huitema ADR. Optimizing drug development of anti-cancer drugs in children using modelling and simulation British Journal of Clinical Pharmacology. 76: 30-47. PMID 23216601 DOI: 10.1111/Bcp.12062  0.476
2013 Mallaysamy S, Johnson MG, Rao PGM, Rajakannan T, Bathala L, Arumugam K, Van Hasselt JGC, Ramakrishna D. Population pharmacokinetics of lamotrigine in Indian epileptic patients European Journal of Clinical Pharmacology. 69: 43-52. PMID 22660444 DOI: 10.1007/s00228-012-1311-9  0.315
2012 Van Hasselt JGC, Schellens JHM, Mac Gillavry MR, Beijnen JH, Huitema ADR. Model-based evaluation and optimization of cardiac monitoring protocols for adjuvant treatment of breast cancer with trastuzumab Pharmaceutical Research. 29: 3499-3511. PMID 22907417 DOI: 10.1007/S11095-012-0845-Y  0.473
2012 van Hasselt JG, van den Heuvel MM, Schellens JH, Beijnen JH, Brandsma D, Huitema AD. Severe cannabinoid intoxication in a patient with non-small-cell lung cancer. Journal of Palliative Care. 28: 60-1. PMID 22582474  0.689
2012 van Hasselt JC, van den Heuvel MM, Schellens JH, Beijnen JH, Brandsma D, Huitema A. Severe Cannabinoid Intoxication in A Patient with Non-Small-Cell Lung Cancer Journal of Palliative Care. 28: 60-61. DOI: 10.1177/082585971202800110  0.53
2011 van den Broek MP, Huitema AD, van Hasselt JG, Groenendaal F, Toet MC, Egberts TC, de Vries LS, Rademaker CM. Lidocaine (lignocaine) dosing regimen based upon a population pharmacokinetic model for preterm and term neonates with seizures. Clinical Pharmacokinetics. 50: 461-9. PMID 21651313 DOI: 10.2165/11589160-000000000-00000  0.669
2011 Van Hasselt JGC, Boekhout AH, Beijnen JH, Schellens JHM, Huitema ADR. Population pharmacokinetic-pharmacodynamic analysis of trastuzumab- associated cardiotoxicity Clinical Pharmacology and Therapeutics. 90: 126-132. PMID 21633346 DOI: 10.1038/Clpt.2011.74  0.511
Low-probability matches (unlikely to be authored by this person)
2023 Janssen JM, Damoiseaux D, van Hasselt JGC, Amant FCH, van Calsteren K, Beijnen JH, Huitema ADR, Dorlo TPC. Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs. Clinical Pharmacokinetics. PMID 37351792 DOI: 10.1007/s40262-023-01263-1  0.292
2019 Illamola SM, Sherwin CM, van Hasselt JGC. Clinical Pharmacokinetics of Amikacin in Pediatric Patients: A Comprehensive Review of Population Pharmacokinetic Analyses. Clinical Pharmacokinetics. 57: 1217-1228. PMID 29572662 DOI: 10.1007/s40262-018-0641-x  0.284
2018 de Vries Schultink AHM, Boekhout AH, Gietema JA, Burylo AM, Dorlo TPC, van Hasselt JGC, Schellens JHM, Huitema ADR. Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens. Journal of Pharmacokinetics and Pharmacodynamics. PMID 29429038 DOI: 10.1007/S10928-018-9579-8  0.272
2012 van den Broek MP, Groenendaal F, Toet MC, van Straaten HL, van Hasselt JG, Huitema AD, de Vries LS, Egberts AC, Rademaker CM. Pharmacokinetics and clinical efficacy of phenobarbital in asphyxiated newborns treated with hypothermia: a thermopharmacological approach. Clinical Pharmacokinetics. 51: 671-9. PMID 23018530 DOI: 10.1007/S40262-012-0004-Y  0.262
2023 Zwep LB, Guo T, Nagler T, Knibbe CAJ, Meulman JJ, van Hasselt JGC. Virtual Patient Simulation Using Copula Modeling. Clinical Pharmacology and Therapeutics. PMID 37946529 DOI: 10.1002/cpt.3099  0.258
2020 Guo T, van Hest RM, Zwep LB, Roggeveen LF, Fleuren LM, Bosman RJ, van der Voort PHJ, Girbes ARJ, Mathot RAA, Elbers PWG, van Hasselt JGC. Optimizing Predictive Performance of Bayesian Forecasting for Vancomycin Concentration in Intensive Care Patients. Pharmaceutical Research. 37: 171. PMID 32830297 DOI: 10.1007/S11095-020-02908-7  0.257
2023 Fu Y, Snelder N, Guo T, van der Graaf PH, van Hasselt JGC. Evaluation of a Cardiovascular Systems Model for Design and Analysis of Hemodynamic Safety Studies. Pharmaceutics. 15. PMID 37111660 DOI: 10.3390/pharmaceutics15041175  0.249
2020 Aulin LBS, De Paepe P, Dhont E, de Jaeger A, Vande Walle J, Vandenberghe W, McWhinney BC, Ungerer JPJ, van Hasselt JGC, De Cock PAJG. Population Pharmacokinetics of Unbound and Total Teicoplanin in Critically Ill Pediatric Patients. Clinical Pharmacokinetics. 60: 353-363. PMID 33030704 DOI: 10.1007/s40262-020-00945-4  0.24
2016 Illamola SM, Colom H, van Hasselt JG. Evaluating renal function and age as predictors of amikacin clearance in neonates: model-based analysis and optimal dosing strategies. British Journal of Clinical Pharmacology. 82: 793-805. PMID 27198625 DOI: 10.1111/bcp.13016  0.234
2022 Fu Y, Taghvafard H, Said MM, Rossman EI, Collins TA, Billiald-Desquand S, Leishman D, van der Graaf PH, van Hasselt JGC, Snelder N. A novel cardiovascular systems model to quantify drugs effects on the inter-relationship between contractility and other hemodynamic variables. Cpt: Pharmacometrics & Systems Pharmacology. PMID 35213797 DOI: 10.1002/psp4.12774  0.233
2022 Guo T, Abdulla A, Koch BCP, van Hasselt JGC, Endeman H, Schouten JA, Elbers PWG, Brüggemann RJM, van Hest RM. Pooled Population Pharmacokinetic Analysis for Exploring Ciprofloxacin Pharmacokinetic Variability in Intensive Care Patients. Clinical Pharmacokinetics. 61: 869-879. PMID 35262847 DOI: 10.1007/s40262-022-01114-5  0.231
2017 Ramamoorthy A, Sadler BM, van Hasselt JGC, Elassaiss-Schaap J, Kasichayanula S, Edwards AY, van der Graaf PH, Zhang L, Wagner JA. Crowdsourced Asparagus Urinary Odor Population Kinetics. Cpt: Pharmacometrics & Systems Pharmacology. PMID 29239147 DOI: 10.1002/psp4.12264  0.23
2023 Mehta K, Guo T, van der Graaf PH, van Hasselt JGC. Model-based dose optimization framework for bedaquiline, pretomanid and linezolid for the treatment of drug-resistant tuberculosis. British Journal of Clinical Pharmacology. 90: 463-474. PMID 37817504 DOI: 10.1111/bcp.15925  0.228
2020 Guo T, van Hest RM, Fleuren LM, Roggeveen LF, Bosman RJ, van der Voort PHJ, Girbes ARJ, Mathot RAA, van Hasselt JGC, Elbers PWG. Why we should sample sparsely and aim for a higher target: lessons from model-based therapeutic drug monitoring (TDM) of vancomycin in intensive care patients. British Journal of Clinical Pharmacology. PMID 32715505 DOI: 10.1111/Bcp.14498  0.224
2021 Zwep LB, Duisters KLW, Jansen M, Guo T, Meulman JJ, Upadhyay PJ, van Hasselt JGC. Identification of high-dimensional omics-derived predictors for tumor growth dynamics using machine learning and pharmacometric modeling. Cpt: Pharmacometrics & Systems Pharmacology. PMID 33792207 DOI: 10.1002/psp4.12603  0.222
2017 Yamamoto Y, Välitalo PA, Wong YC, Huntjens DR, Proost JH, Vermeulen A, Krauwinkel W, Beukers MW, Kokki H, Kokki M, Danhof M, van Hasselt JGC, de Lange ECM. Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 29133240 DOI: 10.1016/j.ejps.2017.11.011  0.221
2021 Aulin LBS, de Lange DW, Saleh MAA, van der Graaf PH, Völler S, van Hasselt JGC. Biomarker-Guided Individualization of Antibiotic Therapy. Clinical Pharmacology and Therapeutics. PMID 33559152 DOI: 10.1002/cpt.2194  0.221
2022 Yin A, van Hasselt JGC, Guchelaar HJ, Friberg LE, Moes DJAR. Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance. Scientific Reports. 12: 4206. PMID 35273301 DOI: 10.1038/s41598-022-08012-7  0.218
2011 Krekels EHJ, Van Hasselt JGC, Tibboel D, Danhof M, Knibbe CAJ. Systematic evaluation of the descriptive and predictive performance of Paediatric morphine population models Pharmaceutical Research. 28: 797-811. PMID 21153913 DOI: 10.1007/s11095-010-0333-1  0.218
2024 Yin A, Veerman GDM, van Hasselt JGC, Steendam CMJ, Dubbink HJ, Guchelaar HJ, Friberg LE, Dingemans AC, Mathijssen RHJ, Moes DJAR. Quantitative modeling of tumor dynamics and development of drug resistance in non-small cell lung cancer patients treated with erlotinib. Cpt: Pharmacometrics & Systems Pharmacology. PMID 38375997 DOI: 10.1002/psp4.13105  0.217
2010 Lo YL, Van Hasselt JGC, Heng SC, Lim CT, Lee TC, Charles BG. Population pharmacokinetics of vancomycin in premature malaysian neonates: Identification of predictors for dosing determination Antimicrobial Agents and Chemotherapy. 54: 2626-2632. PMID 20385872 DOI: 10.1128/AAC.01370-09  0.213
2020 Centanni M, Moes DJAR, Trocóniz IF, Ciccolini J, van Hasselt JGC. Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors. Clinical Pharmacokinetics. 58: 835-857. PMID 30815848 DOI: 10.1007/s40262-019-00748-2  0.211
2017 Kohler I, Hankemeier T, van der Graaf PH, Knibbe CAJ, van Hasselt JGC. Integrating clinical metabolomics-based biomarker discovery and clinical pharmacology to enable precision medicine. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28502671 DOI: 10.1016/j.ejps.2017.05.018  0.207
2017 Yamamoto Y, Välitalo PA, Huntjens DR, Proost JH, Vermeulen A, Krauwinkel W, Beukers MW, van den Berg DJ, Hartman R, Cheong Wong Y, Danhof M, van Hasselt JGC, de Lange ECM. Predicting drug concentration-time profiles in multiple CNS compartments using a comprehensive physiologically-based pharmacokinetic model. Cpt: Pharmacometrics & Systems Pharmacology. PMID 28891201 DOI: 10.1002/psp4.12250  0.207
2012 Klumpers LE, Beumer TL, van Hasselt JGC, Lipplaa A, Karger LB, Kleinloog HD, Freijer JI, de Kam ML, van Gerven JMA. Novel Δ9-tetrahydrocannabinol formulation Namisol® has beneficial pharmacokinetics and promising pharmacodynamic effects British Journal of Clinical Pharmacology. 74: 42-53. PMID 22680341 DOI: 10.1111/j.1365-2125.2012.04164.x  0.201
2012 Van Hasselt JGC, Green B, Morrish GA. Leveraging physiological data from literature into a pharmacokinetic model to support informative clinical study design in pregnant women Pharmaceutical Research. 29: 1609-1617. PMID 22246291 DOI: 10.1007/s11095-012-0671-2  0.199
2017 de Jesus Antunes N, van Dijkman SC, Lanchote VL, Wichert-Ana L, Coelho EB, Junior VA, Takayanagui OM, Tozatto E, van Hasselt JGC, Pasqua OD. Population pharmacokinetics of oxcarbazepine and its metabolite 10-hydroxycarbazepine in healthy subjects. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28528287 DOI: 10.1016/j.ejps.2017.05.034  0.196
2017 Shim JV, Chun B, van Hasselt JGC, Birtwistle MR, Saucerman JJ, Sobie EA. Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics. Frontiers in Physiology. 8: 651. PMID 28951721 DOI: 10.3389/Fphys.2017.00651  0.192
2012 van Hasselt JGC, Andrew MA, Hebert MF, Tarning J, Vicini P, Mattison DR. The status of pharmacometrics in pregnancy: Highlights from the 3rd American conference on pharmacometrics British Journal of Clinical Pharmacology. 74: 932-939. PMID 22452385 DOI: 10.1111/J.1365-2125.2012.04280.X  0.191
2018 van Hasselt JGC, Iyengar R. Systems Pharmacology: Defining the Interactions of Drug Combinations. Annual Review of Pharmacology and Toxicology. PMID 30260737 DOI: 10.1146/annurev-pharmtox-010818-021511  0.187
2016 Nguyen TH, Mouksassi MS, Holford N, Al-Huniti N, Freedman I, Hooker AC, John J, Karlsson MO, Mould DR, Pérez Ruixo JJ, Plan EL, Savic R, van Hasselt JG, Weber B, Zhou C, et al. Model evaluation of continuous data pharmacometric models: Metrics and graphics. Cpt: Pharmacometrics & Systems Pharmacology. PMID 27884052 DOI: 10.1002/psp4.12161  0.179
2022 Mehta K, Guo T, Wallis RS, van der Graaf PH, van Hasselt JGC. Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy. Antimicrobial Agents and Chemotherapy. 66: e0036622. PMID 35862740 DOI: 10.1128/aac.00366-22  0.177
2015 van Hasselt JG, van der Graaf PH. Towards integrative systems pharmacology models in oncology drug development. Drug Discovery Today. Technologies. 15: 1-8. PMID 26464083 DOI: 10.1016/j.ddtec.2015.06.004  0.174
2015 van Hasselt JG, van der Graaf PH. Towards integrative systems pharmacology models in oncology drug development. Drug Discovery Today. Technologies. 15: 1-8. PMID 26464083 DOI: 10.1016/j.ddtec.2015.06.004  0.174
2022 Yin A, van Hasselt JGC, Guchelaar HJ, Friberg LE, Moes DJAR. Publisher Correction: Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance. Scientific Reports. 12: 4879. PMID 35318415 DOI: 10.1038/s41598-022-09014-1  0.173
2020 van Hasselt JGC, Rahman R, Hansen J, Stern A, Shim JV, Xiong Y, Pickard A, Jayaraman G, Hu B, Mahajan M, Gallo JM, Goldfarb J, Sobie EA, Birtwistle MR, Schlessinger A, et al. Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity. Nature Communications. 11: 4809. PMID 32968055 DOI: 10.1038/s41467-020-18396-7  0.172
2016 van Hasselt JG, Rizk ML, Lala M, Chavez-Eng C, Visser SA, Kerbusch T, Danhof M, Rao G, van der Graaf PH. Pooled population pharmacokinetic model of imipenem in plasma and the lung epithelial lining fluid. British Journal of Clinical Pharmacology. PMID 26852277 DOI: 10.1111/bcp.12901  0.171
2019 Yin A, Moes DJAR, van Hasselt JGC, Swen JJ, Guchelaar HJ. A review of mathematical models for tumor dynamics and treatment resistance evolution of solid tumors. Cpt: Pharmacometrics & Systems Pharmacology. PMID 31250989 DOI: 10.1002/psp4.12450  0.17
2023 Mehta K, Guo T, van der Graaf PH, van Hasselt JGC. Predictions of Bedaquiline and Pretomanid Target Attainment in Lung Lesions of Tuberculosis Patients using Translational Minimal Physiologically Based Pharmacokinetic Modeling. Clinical Pharmacokinetics. 62: 519-532. PMID 36802057 DOI: 10.1007/s40262-023-01217-7  0.17
2021 Aulin LBS, Liakopoulos A, van der Graaf PH, Rozen DE, van Hasselt JGC. Design principles of collateral sensitivity-based dosing strategies. Nature Communications. 12: 5691. PMID 34584086 DOI: 10.1038/s41467-021-25927-3  0.166
2018 Yin A, Yamada A, Stam WB, van Hasselt JGC, van der Graaf PH. Quantitative systems pharmacology analysis of drug combination and scaling to humans: the interaction between noradrenaline and vasopressin on vasoconstriction. British Journal of Pharmacology. PMID 29859008 DOI: 10.1111/bph.14385  0.166
2015 Välitalo PA, Griffioen K, Rizk ML, Visser SA, Danhof M, Rao G, van der Graaf PH, van Hasselt JG. Structure-Based Prediction of Anti-infective Drug Concentrations in the Human Lung Epithelial Lining Fluid. Pharmaceutical Research. PMID 26626793 DOI: 10.1007/s11095-015-1832-x  0.166
2009 Wirtz PW, Verschuuren JJ, Van Dijk JG, De Kam ML, Schoemaker RC, Van Hasselt JGC, Titulaer MJ, Tjaden UR, Den Hartigh J, Van Gerven JMA. Efficacy of 3,4-diaminopyridine and pyridostigmine in the treatment of lambert-eaton myasthenic syndrome: A randomized, double-blind, placebo-controlled, crossover study Clinical Pharmacology and Therapeutics. 86: 44-48. PMID 19357643 DOI: 10.1038/clpt.2009.35  0.162
2022 Aulin LBS, Tandar ST, van Zijp T, van Ballegooie E, van der Graaf PH, Saleh MAA, Välitalo P, van Hasselt JGC. Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations. Clinical Pharmacokinetics. 1-14. PMID 36401151 DOI: 10.1007/s40262-022-01186-3  0.154
2016 Yamamoto Y, Välitalo PA, van den Berg DJ, Hartman R, van den Brink W, Wong YC, Huntjens DR, Proost JH, Vermeulen A, Krauwinkel W, Bakshi S, Aranzana-Climent V, Marchand S, Dahyot-Fizelier C, Couet W, ... ... van Hasselt JG, et al. A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations. Pharmaceutical Research. PMID 27864744 DOI: 10.1007/s11095-016-2065-3  0.154
2020 Guo T, van Hest RM, Zwep LB, Roggeveen LF, Fleuren LM, Bosman RJ, van der Voort PHJ, Girbes ARJ, Mathot RAA, Elbers PWG, van Hasselt JGC. Correction to: Optimizing Predictive Performance of Bayesian Forecasting for Vancomycin Concentration in Intensive Care Patients. Pharmaceutical Research. 37: 223. PMID 37452467 DOI: 10.1007/s11095-020-02934-5  0.153
2011 Dumont GJH, Van Hasselt JGC, De Kam M, Van Gerven JMA, Touw DJ, Buitelaar JK, Verkes RJ. Acute psychomotor, memory and subjective effects of MDMA and THC co-administration over time in healthy volunteers Journal of Psychopharmacology. 25: 478-489. PMID 20817749 DOI: 10.1016/S0924-977X(10)70288-1  0.148
2016 De Cock PA, Mulla H, Desmet S, De Somer F, McWhinney BC, Ungerer JP, Moerman A, Commeyne S, Vande Walle J, Francois K, Van Hasselt JG, De Paepe P. Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass to optimize dosing regimens for children undergoing cardiac surgery. The Journal of Antimicrobial Chemotherapy. PMID 27999040 DOI: 10.1093/jac/dkw496  0.146
2011 Liem-Moolenaar M, de Boer P, Timmers M, Schoemaker RC, van Hasselt JGC, Schmidt S, van Gerven JMA. Pharmacokinetic-pharmacodynamic relationships of central nervous system effects of scopolamine in healthy subjects British Journal of Clinical Pharmacology. 71: 886-898. PMID 21306419 DOI: 10.1111/j.1365-2125.2011.03936.x  0.143
2023 Tandar ST, Aulin LBS, Leemkuil EMJ, Liakopoulos A, van Hasselt JGC. Semi-mechanistic modeling of resistance development to β-lactam and β-lactamase-inhibitor combinations. Journal of Pharmacokinetics and Pharmacodynamics. PMID 38008877 DOI: 10.1007/s10928-023-09895-3  0.141
2023 Liu F, Aulin LBS, Manson ML, Krekels EHJ, van Hasselt JGC. Unraveling the Effects of Acute Inflammation on Pharmacokinetics: A Model-Based Analysis Focusing on Renal Glomerular Filtration Rate and Cytochrome P450 3A4-Mediated Metabolism. European Journal of Drug Metabolism and Pharmacokinetics. 48: 623-631. PMID 37715056 DOI: 10.1007/s13318-023-00852-6  0.138
2015 Klumpers LE, Beumer TL, Van Hasselt JGC, Lipplaa A, Karger LB, Kleinloog HD, De Kam ML, Van Gerven JMA. Novel Δ9-tetrahydrocannabinol formulation Namisol has beneficial pharmacokinetics and promising pharmacodynamic effects | Namisol: Een nieuwe formulering van Δ9-tetrahydrocannabinol met gunstige farmacokinetiek en veelbelovende farmacodynamische effecten Pharmaceutisch Weekblad. 150: 122-131.  0.137
2021 Keij FM, Koch BEV, Lozano Vigario F, Simons SHP, van Hasselt JGC, Taal HR, Knibbe CAJ, Spaink HP, Reiss IKM, Krekels EHJ. Zebrafish larvae as experimental model to expedite the search for new biomarkers and treatments for neonatal sepsis. Journal of Clinical and Translational Science. 5: e140. PMID 34422320 DOI: 10.1017/cts.2021.803  0.137
2003 van Hasselt JD. What doctors should look for in patients presenting with erectile dysfunction South African Psychiatry Review. 6: 29-30.  0.134
2023 Gülave B, Budda D, Saleh MA, van Hasselt JC, de Lange EC. Does nonlinear blood-brain barrier transport matter for (lower) morphine dosing strategies? European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 187: 106482. PMID 37247795 DOI: 10.1016/j.ejps.2023.106482  0.13
2024 den Hartog I, Zwep LB, Meulman JJ, Hankemeier T, van de Garde EMW, van Hasselt JGC. Longitudinal metabolite profiling of Streptococcus pneumoniae-associated community-acquired pneumonia. Metabolomics : Official Journal of the Metabolomic Society. 20: 35. PMID 38441696 DOI: 10.1007/s11306-024-02091-5  0.129
2021 Mehta K, Spaink HP, Ottenhoff THM, van der Graaf PH, van Hasselt JGC. Host-directed therapies for tuberculosis: quantitative systems pharmacology approaches. Trends in Pharmacological Sciences. PMID 34916092 DOI: 10.1016/j.tips.2021.11.016  0.125
2021 den Hartog I, Zwep LB, Vestjens SMT, Harms AC, Voorn GP, de Lange DW, Bos WJW, Hankemeier T, van de Garde EMW, van Hasselt JGC. Metabolomic profiling of microbial disease etiology in community-acquired pneumonia. Plos One. 16: e0252378. PMID 34086721 DOI: 10.1371/journal.pone.0252378  0.124
2018 Aulin LBS, Valitalo PA, Rizk ML, Visser SAG, Rao G, van der Graaf PH, van Hasselt JGC. Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans. Pharmaceutical Research. 35: 26. PMID 29368211 DOI: 10.1007/s11095-017-2336-7  0.123
2023 Bock M, Theut AM, van Hasselt JGC, Wang H, Fuursted K, Høiby N, Lerche CJ, Ihlemann N, Gill S, Christiansen U, Nielsen HL, Lemming L, Elming H, Povlsen JA, Bruun NE, et al. Attainment of target antibiotic levels by oral treatment of left-sided infective endocarditis: a POET substudy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 36947131 DOI: 10.1093/cid/ciad168  0.123
2021 Poppe M, Clodi C, Schriefl C, Mueller M, Sunder-Plaßmann R, Reiter B, Rechenmacher M, van Os W, van Hasselt JGC, Holzer M, Herkner H, Schwameis M, Jilma B, Schoergenhofer C, Weiser C. Targeted temperature management after cardiac arrest is associated with reduced metabolism of pantoprazole - A probe drug of CYP2C19 metabolism. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 146: 112573. PMID 34959115 DOI: 10.1016/j.biopha.2021.112573  0.123
2024 Mehta K, Balazki P, van der Graaf PH, Guo T, van Hasselt JGC. Predictions of Bedaquiline Central Nervous System Exposure in Patients with Tuberculosis Meningitis Using Physiologically based Pharmacokinetic Modeling. Clinical Pharmacokinetics. PMID 38530588 DOI: 10.1007/s40262-024-01363-6  0.12
2024 van Os W, Pham AD, Eberl S, Minichmayr IK, van Hasselt JGC, Zeitlinger M. Integrative model-based comparison of target site-specific antimicrobial effects: a case study with ceftaroline and lefamulin. International Journal of Antimicrobial Agents. 107148. PMID 38508535 DOI: 10.1016/j.ijantimicag.2024.107148  0.12
1951 van HASSELT JA. Glioblastosis. | Glioblastose. Nederlands Tijdschrift Voor Geneeskunde. 95: 79-81. PMID 14806670  0.12
2022 Liu F, Aulin LBS, Guo T, Krekels EHJ, Moerland M, van der Graaf PH, van Hasselt JGC. Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations. British Journal of Clinical Pharmacology. 88: 5420-5427. PMID 35921300 DOI: 10.1111/bcp.15476  0.114
2022 Liu F, Aulin LBS, Kossen SSA, Cathalina J, Bremmer M, Foks AC, van der Graaf PH, Moerland M, van Hasselt JGC. A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis. Journal of Pharmacokinetics and Pharmacodynamics. 49: 645-655. PMID 36261775 DOI: 10.1007/s10928-022-09828-6  0.112
2021 Thomson KM, Dyer C, Liu F, Sands K, Portal E, Carvalho MJ, Barrell M, Boostrom I, Dunachie S, Farzana R, Ferreira A, Frayne F, Hassan B, Jones E, Jones L, ... ... van Hasselt JGC, et al. Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an international microbiology and drug evaluation prospective substudy (BARNARDS). The Lancet. Infectious Diseases. PMID 34384533 DOI: 10.1016/S1473-3099(21)00050-5  0.106
2022 Vinkenoog M, Steenhuis M, Brinke AT, van Hasselt JGC, Janssen MP, van Leeuwen M, Swaneveld FH, Vrielink H, van de Watering L, Quee F, van den Hurk K, Rispens T, Hogema B, van der Schoot CE. Associations Between Symptoms, Donor Characteristics and IgG Antibody Response in 2082 COVID-19 Convalescent Plasma Donors. Frontiers in Immunology. 13: 821721. PMID 35296077 DOI: 10.3389/fimmu.2022.821721  0.106
2022 Kok M, Maton L, van der Peet M, Hankemeier T, van Hasselt JGC. Unraveling antimicrobial resistance using metabolomics. Drug Discovery Today. 27: 1774-1783. PMID 35341988 DOI: 10.1016/j.drudis.2022.03.015  0.099
2017 Goulooze SC, Krekels EHJ, van Dijk M, Tibboel D, van der Graaf PH, Hankemeier T, Knibbe CAJ, van Hasselt JGC. Towards personalized treatment of pain using a quantitative systems pharmacology approach. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. S32-S38. PMID 28506867 DOI: 10.1016/j.ejps.2017.05.027  0.096
2023 Bock M, Van Hasselt JGC, Schwartz F, Wang H, Høiby N, Fuursted K, Ihlemann N, Gill S, Christiansen U, Bruun NE, Elming H, Povlsen JA, Køber L, Høfsten DE, Fosbøl EL, et al. Rifampicin reduces plasma concentration of linezolid in patients with infective endocarditis. The Journal of Antimicrobial Chemotherapy. 78: 2840-2848. PMID 37823408 DOI: 10.1093/jac/dkad316  0.093
2009 Dumont GJ, Kramers C, Sweep FC, Touw DJ, Van Hasselt JG, De Kam M, Van Gerven JM, Buitelaar JK, Verkes RJ. Cannabis coadministration potentiates the effects of ecstasy on heart rate and temperature in humans Clinical Pharmacology and Therapeutics. 86: 160-166. PMID 19440186 DOI: 10.1038/Clpt.2009.62  0.09
2020 Aulin LBS, Koumans CIM, Haakman Y, van Os W, Kraakman MEM, Gooskens J, Smits WK, Liakopoulos A, van Hasselt JGC. Distinct evolution of colistin resistance associated with experimental resistance evolution models in Klebsiella pneumoniae. The Journal of Antimicrobial Chemotherapy. PMID 33150358 DOI: 10.1093/jac/dkaa450  0.087
2019 Calizo RC, Bhattacharya S, van Hasselt JGC, Wei C, Wong JS, Wiener RJ, Ge X, Wong NJ, Lee JJ, Cuttitta CM, Jayaraman G, Au VH, Janssen W, Liu T, Li H, et al. Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity. Nature Communications. 10: 2061. PMID 31053734 DOI: 10.1038/S41467-019-09936-X  0.087
2022 Aulin LBS, Kleijburg A, Moerland M, van Hasselt JGC. Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 71: 999-1001. PMID 35861876 DOI: 10.1007/s00011-022-01610-1  0.084
2017 Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, Jayaraman G, Lim R, Bouhaddou M, Ornelas L, Bochicchio J, Lenaeus L, Stocksdale J, Shim J, Gomez E, et al. A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries. Scientific Reports. 7: 14626. PMID 29116112 DOI: 10.1038/S41598-017-14892-X  0.082
2021 Zwep LB, Haakman Y, Duisters KLW, Meulman JJ, Liakopoulos A, van Hasselt JGC. Identification of antibiotic collateral sensitivity and resistance interactions in population surveillance data. Jac-Antimicrobial Resistance. 3: dlab175. PMID 34859221 DOI: 10.1093/jacamr/dlab175  0.081
2022 Liakopoulos A, Aulin LBS, Buffoni M, Fragkiskou E, van Hasselt JGC, Rozen DE. Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121768119. PMID 35476512 DOI: 10.1073/pnas.2121768119  0.076
2021 Rahman R, Zatorski N, Hansen J, Xiong Y, van Hasselt JGC, Sobie EA, Birtwistle MR, Azeloglu EU, Iyengar R, Schlessinger A. Protein structure-based gene expression signatures. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33941686 DOI: 10.1073/pnas.2014866118  0.069
2013 Klumpers LE, Roy C, Ferron G, Turpault S, Poitiers F, Pinquier JL, van Hasselt JGC, Zuurman L, Erwich FAS, van Gerven JMA. Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ9-tetrahydrocannabinol-induced central nervous system and heart rate effects in humans British Journal of Clinical Pharmacology. 76: 65-77. PMID 23278647 DOI: 10.1111/bcp.12071  0.064
2023 den Hartog I, Karu N, Zwep LB, Voorn GP, van de Garde EMW, Hankemeier T, van Hasselt JGC. Differential metabolic host response to pathogens associated with community-acquired pneumonia. Metabolism Open. 18: 100239. PMID 37025095 DOI: 10.1016/j.metop.2023.100239  0.06
2014 Bloch EM, Shah A, Kaidarova Z, Laperche S, Lefrere JJ, van Hasselt J, Zacharias P, Murphy EL, Kayembe MK, Chinorumba A, Gonnetsweng GG, Mphele J, Verde C, Rocha J, Okyere M, et al. A pilot external quality assurance study of transfusion screening for HIV, HCV and HBsAG in 12 African countries Vox Sanguinis. 107: 333-342. PMID 25052195 DOI: 10.1111/vox.12182  0.054
1949 VAN HASSELT JA. Not available | Sarcoid van Besnier-Boeck in een spier. Nederlands Tijdschrift Voor Geneeskunde. 93: 1280. PMID 18150390  0.052
2012 Van Den Berg K, Van Hasselt J, Bloch E, Crookes R, Kelley J, Berger J, Ingram C, Dippenaar A, Thejpal R, Littleton N, Elliz T, Reubenson G, Cotton M, Hull JC, Moodley P, et al. A review of the use of blood and blood products in HIV-infected patients Southern African Journal of Hiv Medicine. 13: 87-103.  0.05
1948 VAN HASSELT JA. Not available | Rheumatische aandoeningen van het zenuwstelsel. Nederlands Tijdschrift Voor Geneeskunde. 92: 67-69. PMID 18902973  0.05
1949 VAN HASSELT JA. [Not Available] | Spongioblastosis multiformis gangliodes Nederlands Tijdschrift Voor Geneeskunde. 93: 1278-1280. PMID 18145118  0.048
1948 VAN HASSELT JA. Not Available | Rheumatische hersenaandoeningen Nederlands Tijdschrift Voor Geneeskunde. 92: 3356. PMID 18099274  0.048
2018 Krzyzanski W, van Hasselt JGC. Special issue: mathematical pharmacology. Journal of Pharmacokinetics and Pharmacodynamics. 45: 1. PMID 29299711 DOI: 10.1007/s10928-017-9566-5  0.042
2018 Krzyzanski W, van Hasselt JGC. Special issue: mathematical pharmacology. Journal of Pharmacokinetics and Pharmacodynamics. 45: 1. PMID 29299711 DOI: 10.1007/s10928-017-9566-5  0.042
1983 van Hasselt JL. Report GZ'83 is misleading! Farewell address by J. L. van Hasselt, president of the Section Mental Health Care of the NZR (National Hospital Council) | Rapport GZ'83 is misleidend! Afscheidsrede van J. L. van Hasselt, voorzitter van de Sectie geestelijke gezondheidszorg van de NZR. Tijdschrift Voor Ziekenverpleging. 36: 789-790. PMID 6560927  0.037
1885 van Hasselt J, de Koning J. Een rijst-polder - Proeve eener berekening van het rentegevend vermogen van gronden op Java, door middel van landbouw-werktuigen en stoom in cultuur gebracht en met padie beplant De Economist. 34: 577-616. DOI: 10.1007/BF02184847  0.026
2018 Saleh MAA, van de Garde EMW, van Hasselt JGC. Host-response biomarkers for the diagnosis of bacterial respiratory tract infections. Clinical Chemistry and Laboratory Medicine. PMID 30183665 DOI: 10.1515/cclm-2018-0682  0.025
1992 Van Hasselt JP. Reservoir compaction and surface subsidence resulting from oil and gas production. A review of theoretical and experimental research approaches Geologie En Mijnbouw. 71: 107-118.  0.025
2003 Van Riel CBM, Van Hasselt JJ. Conversion of organizational identity research findings into actions Corporate and Organizational Identities: Integrating Strategy, Marketing, Communication and Organizational Perspectives. 156-174. DOI: 10.4324/9780203361726  0.017
1987 van Hasselt JC, Kaper HP. NEW LINES: THE NEW FLEVO LINE, AN ENVIRONMENT-FRIENDLY PROJECT. Rail International. 13: 38-44.  0.014
1952 VAN HASSELT JA. Medulloblastoma. | Medullo-blastomen. Nederlands Tijdschrift Voor Geneeskunde. 96: 1181-1182. PMID 14957135  0.014
1976 Huijben MJ, van Hasselt JP, van der Weg K, van der Lugt W. Density of liquid sodium-potassium and potassium-rubidium alloys Scripta Metallurgica. 10: 571-574. DOI: 10.1016/0036-9748(76)90265-9  0.01
1951 van HASSELT JA. Traumatic pontile hemorrhage. | Traumatische ponsbloedingen. Nederlands Tijdschrift Voor Geneeskunde. 95: 77-79. PMID 14806669  0.01
1934 van der Horst L, van Hasselt JA. Syringomyelie oder Tumor medullae? Deutsche Zeitschrift FüR Nervenheilkunde. 133: 129-135. DOI: 10.1007/BF01760232  0.01
1910 van Hasselt JFB. Notiz zur Pepsin-Chymosinfrage Hoppe-Seyler's Zeitschrift Fur Physiologische Chemie. 70: 171-185. DOI: 10.1515/bchm2.1910.70.2-3.171  0.01
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