Charles Huang Chen - Publications

Affiliations: 
King's College London, London, UK 
Area:
Peptide therapeutics and membrane biology

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ghimire J, Hart RJ, Soldano A, Chen CH, Guha S, Hoffmann JP, Hall KM, Sun L, Nelson BJ, Lu TK, Kolls JK, Rivera M, Morici LA, Wimley WC. Optimization of Host Cell-Compatible, Antimicrobial Peptides Effective against Biofilms and Clinical Isolates of Drug-Resistant Bacteria. Acs Infectious Diseases. PMID 36961222 DOI: 10.1021/acsinfecdis.2c00640  0.603
2023 Chen CH, Zan B, Ulmschneider JP, Wimley WC, Lu TK, Ulmschneider MB, Zhou L. Development of membrane-active peptide therapeutics in oncology. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3482. PMID 36739581 DOI: 10.1002/psc.3482  0.781
2022 Chen CH, Bepler T, Pepper K, Fu D, Lu TK. Synthetic molecular evolution of antimicrobial peptides. Current Opinion in Biotechnology. 75: 102718. PMID 35395425 DOI: 10.1016/j.copbio.2022.102718  0.707
2022 Chen CH, Pepper K, Ulmschneider JP, Ulmschneider MB, Lu TK. Predicting Membrane-Active Peptide Dynamics in Fluidic Lipid Membranes. Methods in Molecular Biology (Clifton, N.J.). 2405: 115-136. PMID 35298811 DOI: 10.1007/978-1-0716-1855-4_6  0.801
2022 Chen CH, Liu YH, Eskandari A, Ghimire J, Lin LC, Fang ZS, Wimley WC, Ulmschneider JP, Suntharalingam K, Hu CJ, Ulmschneider MB. Integrated Design of a Membrane-Lytic Peptide-Based Intravenous Nanotherapeutic Suppresses Triple-Negative Breast Cancer. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2105506. PMID 35246961 DOI: 10.1002/advs.202105506  0.73
2021 Chen CH, Starr CG, Guha S, Wimley WC, Ulmschneider MB, Ulmschneider JP. Tuning of a Membrane-Perforating Antimicrobial Peptide to Selectively Target Membranes of Different Lipid Composition. The Journal of Membrane Biology. PMID 33564914 DOI: 10.1007/s00232-021-00174-1  0.785
2020 Chen CH, Melo MC, Berglund N, Khan A, de la Fuente C, Ulmschneider JP, Ulmschneider MB. Understanding and modelling the interactions of peptides with membranes: from partitioning to self-assembly. Current Opinion in Structural Biology. 61: 160-166. PMID 32006812 DOI: 10.1016/J.Sbi.2019.12.021  0.745
2020 Chen CH, Lu TK. Development and Challenges of Antimicrobial Peptides for Therapeutic Applications. Antibiotics (Basel, Switzerland). 9. PMID 31941022 DOI: 10.3390/Antibiotics9010024  0.647
2019 Chen C, Starr CG, Troendle EP, Wiedman G, Wimley WC, Ulmschneider JP, Ulmschneider MB. Simulation-guided rational de novo design of a small pore-forming antimicrobial peptide. Journal of the American Chemical Society. PMID 30839209 DOI: 10.1021/Jacs.8B11939  0.555
2017 Wang Q, Chen CH, Chung CY, Priola J, Chu JH, Tang J, Ulmschneider MB, Betenbaugh MJ. Proline-rich chaperones are compared computationally and experimentally for their abilities to facilitate recombinant butyrylcholinesterase tetramerization in CHO cells. Biotechnology Journal. PMID 29024569 DOI: 10.1002/Biot.201700479  0.639
2016 Wang Y, Chen CH, Hu D, Ulmschneider MB, Ulmschneider JP. Spontaneous formation of structurally diverse membrane channel architectures from a single antimicrobial peptide. Nature Communications. 7: 13535. PMID 27874004 DOI: 10.1038/Ncomms13535  0.73
2016 Chen CH, Khan A, Huang JT, Ulmschneider MB. Mechanisms of membrane-pore formation by amyloidogenic peptides in ALS. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27224887 DOI: 10.1002/chem.201601765  0.719
2015 Li Z, Bansal N, Azarpira A, Bhalla A, Chen CH, Ralph J, Hegg EL, Hodge DB. Chemical and structural changes associated with Cu-catalyzed alkaline-oxidative delignification of hybrid poplar. Biotechnology For Biofuels. 8: 123. PMID 26300970 DOI: 10.1186/S13068-015-0300-5  0.353
2014 Chen CH, Wiedman G, Khan A, Ulmschneider MB. Absorption and folding of melittin onto lipid bilayer membranes via unbiased atomic detail microsecond molecular dynamics simulation. Biochimica Et Biophysica Acta. 1838: 2243-9. PMID 24769159 DOI: 10.1016/j.bbamem.2014.04.012  0.749
2013 Li Z, Chen CH, Hegg EL, Hodge DB. Rapid and effective oxidative pretreatment of woody biomass at mild reaction conditions and low oxidant loadings. Biotechnology For Biofuels. 6: 119. PMID 23971902 DOI: 10.1186/1754-6834-6-119  0.315
2013 Li Z, Chen CH, Liu T, Mathrubootham V, Hegg EL, Hodge DB. Catalysis with Cu(II) (bpy) improves alkaline hydrogen peroxide pretreatment. Biotechnology and Bioengineering. 110: 1078-86. PMID 23192283 DOI: 10.1002/Bit.24793  0.307
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