| Year |
Citation |
Score |
| 2024 |
Oh YH, Becker ML, Mendola KM, Choe LH, Min L, Lee KH, Yigzaw Y, Seay A, Bill J, Li X, Roush DJ, Cramer SM, Menegatti S, Lenhoff AM. Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing. Biotechnology and Bioengineering. PMID 38240126 DOI: 10.1002/bit.28658 |
0.339 |
|
| 2023 |
Dhingra K, Sinha I, Snyder M, Roush D, Cramer SM. Exploring preferred binding domains of IgG1 mAbs to multimodal adsorbents using a combined biophysics and simulation approach. Biotechnology Progress. e3415. PMID 38043031 DOI: 10.1002/btpr.3415 |
0.318 |
|
| 2023 |
Altern SH, Welsh JP, Lyall JY, Kocot AJ, Burgess S, Kumar V, Williams C, Lenhoff AM, Cramer SM. Isotherm model discrimination for multimodal chromatography using mechanistic models derived from high-throughput batch isotherm data. Journal of Chromatography. A. 1693: 463878. PMID 36827799 DOI: 10.1016/j.chroma.2023.463878 |
0.819 |
|
| 2023 |
Dhingra K, Gudhka RB, Cramer SM. Evaluation of preferred binding regions on ubiquitin and IgG1 F for interacting with multimodal cation exchange resins using DEPC labeling/mass spectrometry. Biotechnology and Bioengineering. PMID 36814367 DOI: 10.1002/bit.28361 |
0.813 |
|
| 2022 |
Sinha I, Cramer SM, Ashbaugh HS, Garde S. Connecting Non-Gaussian Water Density Fluctuations to the Lengthscale Dependent Crossover in Hydrophobic Hydration. The Journal of Physical Chemistry. B. PMID 36154059 DOI: 10.1021/acs.jpcb.2c04990 |
0.762 |
|
| 2022 |
Ghosh R, Koley S, Gopal S, Rodrigues AL, Dordick JS, Cramer SM. Evaluation of Lentiviral Vector Stability and Development of Ion Exchange Purification Processes. Biotechnology Progress. e3286. PMID 35808852 DOI: 10.1002/btpr.3286 |
0.808 |
|
| 2022 |
Han X, Shih J, Lin Y, Chai Q, Cramer SM. Development of QSAR models for screening of antibody solubility. Mabs. 14: 2062807. PMID 35442164 DOI: 10.1080/19420862.2022.2062807 |
0.625 |
|
| 2022 |
Sripada SA, Chu W, Williams TI, Teten MA, Mosley BJ, Carbonell RG, Lenhoff AM, Cramer SM, Bill J, Yigzaw Y, Roush DJ, Menegatti S. Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via "flow-through affinity chromatography" using peptide-based adsorbents. Biotechnology and Bioengineering. PMID 35377460 DOI: 10.1002/bit.28096 |
0.427 |
|
| 2022 |
Keller WR, Evans ST, Ferreira G, Robbins D, Cramer SM. Understanding the effects of system differences for parameter estimation and scale-up of high throughput chromatographic data. Journal of Chromatography. A. 1661: 462696. PMID 34875516 DOI: 10.1016/j.chroma.2021.462696 |
0.744 |
|
| 2021 |
Vecchiarello N, Timmick SM, Cramer S. A framework for calculating orthogonal selectivities in multimodal systems directly from cell culture fluid. Biotechnology and Bioengineering. 119: 299-314. PMID 34713893 DOI: 10.1002/bit.27977 |
0.821 |
|
| 2021 |
Parasnavis SS, Niu B, Aspelund M, Chung WK, Snyder M, Cramer SM. Systematic Workflow for Studying Domain Contributions of Bispecific Antibodies to Selectivity in Multimodal Chromatography. Biotechnology and Bioengineering. PMID 34687215 DOI: 10.1002/bit.27967 |
0.798 |
|
| 2021 |
Gudhka RB, Vats M, Bilodeau CL, McCallum SA, McCoy MA, Roush DJ, Snyder MA, Cramer SM. Probing IgG1 F-Multimodal Nanoparticle Interactions: A Combined Nuclear Magnetic Resonance and Molecular Dynamics Simulations Approach. Langmuir : the Acs Journal of Surfaces and Colloids. 37: 12188-12203. PMID 34633195 DOI: 10.1021/acs.langmuir.1c02114 |
0.795 |
|
| 2021 |
Koley S, Altern SH, Vats M, Han X, Jang D, Snyder MA, Belisle C, Cramer SM. Evaluation of guanidine-based multimodal anion exchangers for protein selectivity and orthogonality. Journal of Chromatography. A. 1653: 462398. PMID 34280791 DOI: 10.1016/j.chroma.2021.462398 |
0.825 |
|
| 2021 |
Gopal S, Osborne AE, Hock L, Zemianek J, Fang K, Gee G, Ghosh R, McNally D, Cramer SM, Dordick JS. Advancing a rapid, high throughput screening platform for optimization of lentivirus production. Biotechnology Journal. e2000621. PMID 34260824 DOI: 10.1002/biot.202000621 |
0.773 |
|
| 2021 |
Bhat M, Mullerpatan A, Chen J, Holstein M, Ghose S, Li ZJ, Cramer S. Affinity Precipitation of Monoclonal Antibodies using ELP-Z in the Elution without Resolubilization Mode. Journal of Biotechnology. PMID 34197822 DOI: 10.1016/j.jbiotec.2021.06.020 |
0.803 |
|
| 2021 |
Bilodeau CL, Lau EY, Roush DJ, Snyder MA, Cramer SM. Behavior of Water Near Multimodal Chromatography Ligands and Its Consequences for Modulating Protein-Ligand Interactions. The Journal of Physical Chemistry. B. PMID 34097423 DOI: 10.1021/acs.jpcb.1c01549 |
0.827 |
|
| 2021 |
Crowell LE, Goodwine C, Holt CS, Rocha L, Vega C, Rodriguez SA, Dalvie NC, Tracey MK, Puntel M, Wigdorovitz A, Parreño V, Love KR, Cramer SM, Christopher Love J. Development of a platform process for the production and purification of single-domain antibodies. Biotechnology and Bioengineering. PMID 33624832 DOI: 10.1002/bit.27724 |
0.799 |
|
| 2020 |
Gudhka RB, Bilodeau CL, McCallum SA, McCoy MA, Roush DJ, Snyder MA, Cramer SM. Identification of Preferred Multimodal Ligand Binding Regions on IgG1 F using Nuclear Magnetic Resonance and Molecular Dynamics Simulations. Biotechnology and Bioengineering. PMID 33107976 DOI: 10.1002/bit.27611 |
0.805 |
|
| 2020 |
Gudhka RB, Roush DJ, Cramer SM. A thermodynamic evaluation of antibody-surface interactions in multimodal cation exchange chromatography. Journal of Chromatography. A. 1628: 461479. PMID 32822997 DOI: 10.1016/j.chroma.2020.461479 |
0.799 |
|
| 2020 |
Bilodeau CL, Vecchiarello NA, Altern S, Cramer SM. Quantifying orthogonality and separability: A method for optimizing resin selection and design. Journal of Chromatography. A. 1628: 461429. PMID 32822971 DOI: 10.1016/j.chroma.2020.461429 |
0.812 |
|
| 2020 |
Mullerpatan A, Kane E, Ghosh R, Nascimento A, Andersen H, Cramer S, Karande P. Single Step Purification of a Small Non-mAb Biologic by Peptide-ELP based Affinity Precipitation. Biotechnology and Bioengineering. PMID 32813285 DOI: 10.1002/Bit.27539 |
0.797 |
|
| 2020 |
Bilodeau CL, Lau EY, Cramer SM, Garde S. The Role of Ligand-Ligand Interactions in Multimodal Ligand Conformational Equilibria and Surface Pattern Formation. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 32589849 DOI: 10.1021/Acs.Langmuir.0C00707 |
0.804 |
|
| 2020 |
Coffman J, Marques B, Orozco R, Aswath M, Mohammad H, Zimmerman E, Khouri J, Jan G, Izadi S, Williams A, Sankar K, Walters B, Lin J, Hepbildikler S, Schiel J, ... ... Cramer S, et al. Highland Games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences. Biotechnology and Bioengineering. PMID 32255523 DOI: 10.1002/Bit.27349 |
0.795 |
|
| 2020 |
Robinson J, Roush D, Cramer SM. The effect of pH on antibody retention in multimodal cation exchange chromatographic systems. Journal of Chromatography. A. 460838. PMID 31932086 DOI: 10.1016/j.chroma.2019.460838 |
0.742 |
|
| 2019 |
Mullerpatan A, Chandra D, Kane E, Karande P, Cramer S. Purification of Proteins using Peptide-ELP Based Affinity Precipitation. Journal of Biotechnology. PMID 31874207 DOI: 10.1016/J.Jbiotec.2019.12.012 |
0.816 |
|
| 2019 |
Bilodeau CL, Lau EY, Roush D, Garde S, Cramer SM. Formation of Ligand Clusters on Multimodal Chromatographic Surfaces. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 31603330 DOI: 10.1021/Acs.Langmuir.9B01925 |
0.801 |
|
| 2019 |
Nascimento A, Mullerpatan A, Azevedo AM, Karande P, Cramer S. Development of phage biopanning strategies to identify affinity peptide ligands for kappa light chain Fab fragments. Biotechnology Progress. e2884. PMID 31301216 DOI: 10.1002/Btpr.2884 |
0.804 |
|
| 2019 |
Zhang L, Parasnavis S, Li Z, Chen J, Cramer S. Mechanistic modeling based process development for monoclonal antibody monomer-aggregate separations in multimodal cation exchange chromatography. Journal of Chromatography. A. PMID 31248584 DOI: 10.1016/j.chroma.2019.05.056 |
0.82 |
|
| 2019 |
Bilodeau CL, Lau EY, Cramer SM, Garde S. Conformational Equilibria of Multimodal Chromatography Ligands in Water and Bound to Protein Surfaces. The Journal of Physical Chemistry. B. PMID 31117605 DOI: 10.1021/Acs.Jpcb.9B01218 |
0.816 |
|
| 2019 |
Vecchiarello N, Timmick SM, Goodwine C, Crowell LE, Love KR, Love JC, Cramer SM. A Combined Screening and In Silico Strategy for the Rapid Design of Integrated Downstream Processes for Process and Product-Related Impurity Removal. Biotechnology and Bioengineering. PMID 31081177 DOI: 10.1002/bit.27018 |
0.802 |
|
| 2019 |
Ranjan S, Chung WK, Zhu M, Robbins D, Cramer SM. Implementation of an Experimental and Computational Tool Set to Study Protein-mAb Interactions. Biotechnology Progress. e2825. PMID 31017347 DOI: 10.1002/btpr.2825 |
0.828 |
|
| 2019 |
Ranjan S, Chung WK, Hofele R, Thompson JH, Bee J, Zhang L, Robbins D, Cramer SM. Investigation of cathepsin D-mAb interactions using a combined experimental and computational tool set. Biotechnology and Bioengineering. PMID 30882893 DOI: 10.1002/Bit.26968 |
0.823 |
|
| 2018 |
Crowell LE, Lu AE, Love KR, Stockdale A, Timmick SM, Wu D, Wang YA, Doherty W, Bonnyman A, Vecchiarello N, Goodwine C, Bradbury L, Brady JR, Clark JJ, Colant NA, ... ... Cramer SM, et al. On-demand manufacturing of clinical-quality biopharmaceuticals. Nature Biotechnology. PMID 30272677 DOI: 10.1038/Nbt.4262 |
0.78 |
|
| 2018 |
Robinson J, Snyder MA, Belisle C, Liao JL, Chen H, He X, Xu Y, Cramer SM. Investigating the impact of aromatic ring substitutions on selectivity for a multimodal anion exchange prototype library. Journal of Chromatography. A. PMID 30041873 DOI: 10.1016/j.chroma.2018.07.049 |
0.785 |
|
| 2018 |
Trasatti JP, Woo J, Ladiwala A, Cramer S, Karande P. Rational Design of Peptide Affinity Ligands for the Purification of Therapeutic Enzymes. Biotechnology Progress. PMID 29694733 DOI: 10.1002/Btpr.2637 |
0.807 |
|
| 2018 |
Timmick SM, Vecchiarello N, Goodwine C, Crowell LE, Love KR, Love JC, Cramer SM. An impurity characterization based approach for the rapid development of integrated downstream purification processes. Biotechnology and Bioengineering. PMID 29679482 DOI: 10.1002/bit.26718 |
0.77 |
|
| 2017 |
Srinivasan K, Sorci M, Sejergaard L, Ranjan S, Belfort G, Cramer SM. Protein Binding Kinetics in Multimodal Systems: Implications for Protein Separations. Analytical Chemistry. PMID 29212318 DOI: 10.1021/Acs.Analchem.7B04158 |
0.819 |
|
| 2017 |
Srinivasan K, Banerjee S, Parimal S, Sejergaard L, Berkovich R, Barquera B, Garde S, Cramer SM. Single molecule force spectroscopy and molecular dynamics simulations as a combined platform for probing protein face specific binding. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 28949551 DOI: 10.1021/Acs.Langmuir.7B03011 |
0.815 |
|
| 2017 |
Keller WR, Evans ST, Ferreira G, Robbins D, Cramer SM. Understanding operational system differences for transfer of miniaturized chromatography column data using simulations. Journal of Chromatography. A. PMID 28811099 DOI: 10.1016/j.chroma.2017.07.091 |
0.758 |
|
| 2017 |
Banerjee S, Parimal S, Cramer SM. A molecular modeling based method to predict elution behavior and binding patches of proteins in multimodal chromatography. Journal of Chromatography. A. PMID 28689580 DOI: 10.1016/J.Chroma.2017.06.059 |
0.833 |
|
| 2016 |
Parimal S, Garde S, Cramer SM. Effect of guanidine and arginine on protein-ligand interactions in multimodal cation-exchange chromatography. Biotechnology Progress. PMID 27997085 DOI: 10.1002/Btpr.2419 |
0.385 |
|
| 2016 |
Robinson JR, Karkov HS, Woo JA, Krogh BO, Cramer SM. QSAR models for prediction of chromatographic behavior of homologous Fab variants. Biotechnology and Bioengineering. PMID 27943241 DOI: 10.1002/bit.26236 |
0.827 |
|
| 2015 |
Karkov HS, Woo J, Krogh BO, Ahmadian H, Cramer SM. Evaluation of selectivity in homologous multimodal chromatographic systems using in silico designed antibody fragment libraries. Journal of Chromatography. A. PMID 26654254 DOI: 10.1016/j.chroma.2015.11.047 |
0.776 |
|
| 2015 |
Keller WR, Evans ST, Ferreira G, Robbins D, Cramer SM. Use of MiniColumns for linear isotherm parameter estimation and prediction of benchtop column performance. Journal of Chromatography. A. 1418: 94-102. PMID 26422303 DOI: 10.1016/j.chroma.2015.09.038 |
0.748 |
|
| 2015 |
Woo J, Parimal S, Brown MR, Heden R, Cramer SM. The effect of geometrical presentation of multimodal cation-exchange ligands on selective recognition of hydrophobic regions on protein surfaces. Journal of Chromatography. A. 1412: 33-42. PMID 26292626 DOI: 10.1016/J.Chroma.2015.07.072 |
0.79 |
|
| 2015 |
Woo JA, Chen H, Snyder MA, Chai Y, Frost RG, Cramer SM. Defining the property space for chromatographic ligands from a homologous series of mixed-mode ligands. Journal of Chromatography. A. 1407: 58-68. PMID 26162668 DOI: 10.1016/j.chroma.2015.06.017 |
0.788 |
|
| 2015 |
Parimal S, Garde S, Cramer SM. Interactions of Multimodal Ligands with Proteins: Insights into Selectivity Using Molecular Dynamics Simulations. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 7512-23. PMID 26030224 DOI: 10.1021/Acs.Langmuir.5B00236 |
0.335 |
|
| 2015 |
Karkov HS, Krogh BO, Woo J, Parimal S, Ahmadian H, Cramer SM. Investigation of protein selectivity in multimodal chromatography using in silico designed Fab fragment variants. Biotechnology and Bioengineering. 112: 2305-15. PMID 25950863 DOI: 10.1002/Bit.25642 |
0.804 |
|
| 2014 |
Srinivasan K, Parimal S, Lopez MM, McCallum SA, Cramer SM. Investigation into the molecular and thermodynamic basis of protein interactions in multimodal chromatography using functionalized nanoparticles. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 13205-16. PMID 25310519 DOI: 10.1021/La502141Q |
0.69 |
|
| 2014 |
Sheth RD, Bhut BV, Jin M, Li Z, Chen W, Cramer SM. Development of an ELP-Z based mAb affinity precipitation process using scaled-down filtration techniques. Journal of Biotechnology. 192: 11-9. PMID 25285370 DOI: 10.1016/J.Jbiotec.2014.09.020 |
0.723 |
|
| 2014 |
Parimal S, Cramer SM, Garde S. Application of a spherical harmonics expansion approach for calculating ligand density distributions around proteins. The Journal of Physical Chemistry. B. 118: 13066-76. PMID 25198149 DOI: 10.1021/Jp506849K |
0.319 |
|
| 2014 |
Carvalho RJ, Woo J, Aires-Barros MR, Cramer SM, Azevedo AM. Phenylboronate chromatography selectively separates glycoproteins through the manipulation of electrostatic, charge transfer, and cis-diol interactions. Biotechnology Journal. 9: 1250-8. PMID 25130283 DOI: 10.1002/biot.201400170 |
0.726 |
|
| 2014 |
Sheth RD, Jin M, Bhut BV, Li Z, Chen W, Cramer SM. Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP-Z stimuli responsive biopolymer. Biotechnology and Bioengineering. 111: 1595-603. PMID 24595842 DOI: 10.1002/Bit.25230 |
0.747 |
|
| 2013 |
Levy MH, Goswami S, Plawsky J, Cramer SM. Parameters Governing the Formation of Photopolymerized Silica Sol-Gel Monoliths in PDMS Microfluidic Chips. Chromatographia. 76: 993-1002. PMID 28450752 DOI: 10.1007/S10337-013-2493-8 |
0.771 |
|
| 2013 |
Levy MH, Plawsky J, Cramer SM. Photopolymerized sol-gel monoliths for separations of glycosylated proteins and peptides in microfluidic chips. Journal of Separation Science. 36: 2358-65. PMID 23703808 DOI: 10.1002/Jssc.201200990 |
0.698 |
|
| 2013 |
Sheth RD, Madan B, Chen W, Cramer SM. High-throughput screening for the development of a monoclonal antibody affinity precipitation step using ELP-z stimuli responsive biopolymers. Biotechnology and Bioengineering. 110: 2664-76. PMID 23616271 DOI: 10.1002/Bit.24945 |
0.726 |
|
| 2013 |
Chandra D, Morrison CJ, Woo J, Cramer S, Karande P. Design of peptide affinity ligands for S-protein: a comparison of combinatorial and de novo design strategies. Molecular Diversity. 17: 357-69. PMID 23532725 DOI: 10.1007/S11030-013-9436-Z |
0.793 |
|
| 2013 |
Holstein MA, Parimal S, McCallum SA, Cramer SM. Effects of urea on selectivity and protein-ligand interactions in multimodal cation exchange chromatography. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 158-67. PMID 23199297 DOI: 10.1021/La302360B |
0.798 |
|
| 2013 |
Madan B, Chaudhary G, Cramer SM, Chen W. ELP-z and ELP-zz capturing scaffolds for the purification of immunoglobulins by affinity precipitation. Journal of Biotechnology. 163: 10-6. PMID 23089730 DOI: 10.1016/J.Jbiotec.2012.10.007 |
0.301 |
|
| 2012 |
Holstein MA, Nikfetrat AAM, Gage M, Hirsh AG, Cramer SM. Improving selectivity in multimodal chromatography using controlled pH gradient elution Journal of Chromatography A. 1233: 152-155. PMID 22406513 DOI: 10.1016/j.chroma.2012.01.074 |
0.763 |
|
| 2012 |
Holstein MA, Chung WK, Parimal S, Freed AS, Barquera B, McCallum SA, Cramer SM. Probing multimodal ligand binding regions on ubiquitin using nuclear magnetic resonance, chromatography, and molecular dynamics simulations. Journal of Chromatography. A. 1229: 113-20. PMID 22281506 DOI: 10.1016/J.Chroma.2011.12.101 |
0.817 |
|
| 2012 |
Holstein MA, Parimal S, McCallum SA, Cramer SM. Mobile phase modifier effects in multimodal cation exchange chromatography. Biotechnology and Bioengineering. 109: 176-86. PMID 21898370 DOI: 10.1002/Bit.23318 |
0.799 |
|
| 2011 |
Sheth RD, Morrison CJ, Cramer SM. Selective displacement chromatography in multimodal cation exchange systems. Journal of Chromatography. A. 1218: 9250-9. PMID 22098931 DOI: 10.1016/j.chroma.2011.10.088 |
0.764 |
|
| 2011 |
Freed AS, Garde S, Cramer SM. Molecular simulations of multimodal ligand-protein binding: elucidation of binding sites and correlation with experiments. The Journal of Physical Chemistry. B. 115: 13320-7. PMID 21942536 DOI: 10.1021/Jp2038015 |
0.835 |
|
| 2011 |
Hou Y, Cramer SM. Evaluation of selectivity in multimodal anion exchange systems: a priori prediction of protein retention and examination of mobile phase modifier effects. Journal of Chromatography. A. 1218: 7813-20. PMID 21937048 DOI: 10.1016/j.chroma.2011.08.080 |
0.595 |
|
| 2011 |
Evans ST, Holstein M, Cramer SM. Detection of trace proteins in multicomponent mixtures using displacement chromatography. Analytical Chemistry. 83: 4184-92. PMID 21524131 DOI: 10.1021/ac200486e |
0.794 |
|
| 2011 |
Hou Y, Morrison CJ, Cramer SM. Classification of protein binding in hydroxyapatite chromatography: synergistic interactions on the molecular scale. Analytical Chemistry. 83: 3709-16. PMID 21495696 DOI: 10.1021/ac103336h |
0.737 |
|
| 2011 |
Freed AS, Cramer SM. Protein-surface interaction maps for ion-exchange chromatography. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 3561-8. PMID 21375221 DOI: 10.1021/la104641z |
0.815 |
|
| 2011 |
Nagrath D, Xia F, Cramer SM. Characterization and modeling of nonlinear hydrophobic interaction chromatographic systems. Journal of Chromatography. A. 1218: 1219-26. PMID 21255785 DOI: 10.1016/J.Chroma.2010.12.111 |
0.742 |
|
| 2011 |
Hou Y, Jiang C, Shukla AA, Cramer SM. Improved process analytical technology for protein a chromatography using predictive principal component analysis tools. Biotechnology and Bioengineering. 108: 59-68. PMID 20672251 DOI: 10.1002/Bit.22886 |
0.81 |
|
| 2010 |
Morrison CJ, Gagnon P, Cramer SM. Purification of monomeric mAb from associated aggregates using selective desorption chromatography in hydroxyapatite systems. Biotechnology and Bioengineering. 108: 813-21. PMID 20967751 DOI: 10.1002/bit.22971 |
0.576 |
|
| 2010 |
Hou Y, Hansen TB, Staby A, Cramer SM. Effects of urea induced protein conformational changes on ion exchange chromatographic behavior. Journal of Chromatography. A. 1217: 7393-400. PMID 20956007 DOI: 10.1016/j.chroma.2010.09.052 |
0.503 |
|
| 2010 |
Chung WK, Freed AS, Holstein MA, McCallum SA, Cramer SM. Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR Proceedings of the National Academy of Sciences of the United States of America. 107: 16811-16816. PMID 20837551 DOI: 10.1073/pnas.1002347107 |
0.835 |
|
| 2010 |
Morrison CJ, Gagnon P, Cramer SM. Unique selectivity windows using selective displacers/eluents and mobile phase modifiers on hydroxyapatite. Journal of Chromatography. A. 1217: 6484-95. PMID 20832806 DOI: 10.1016/j.chroma.2010.08.038 |
0.576 |
|
| 2010 |
Zhang S, Xia K, Chung WK, Cramer SM, Colón W. Identifying kinetically stable proteins with capillary electrophoresis. Protein Science : a Publication of the Protein Society. 19: 888-92. PMID 20091769 DOI: 10.1002/Pro.336 |
0.788 |
|
| 2010 |
Evans ST, Morrison CJ, Freed A, Cramer SM. The effect of feed composition on the behavior of chemically selective displacement systems. Journal of Chromatography. A. 1217: 1249-54. PMID 20045521 DOI: 10.1016/j.chroma.2009.12.020 |
0.771 |
|
| 2010 |
Chung WK, Hou Y, Holstein M, Freed A, Makhatadze GI, Cramer SM. Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein library. Journal of Chromatography. A. 1217: 191-8. PMID 19732898 DOI: 10.1016/J.Chroma.2009.08.005 |
0.834 |
|
| 2010 |
Chung WK, Evans ST, Freed AS, Keba JJ, Baer ZC, Rege K, Cramer SM. Utilization of lysozyme charge ladders to examine the effects of protein surface charge distribution on binding affinity in ion exchange systems. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 759-68. PMID 19678624 DOI: 10.1021/La902135T |
0.814 |
|
| 2009 |
Morrison CJ, Breneman CM, Moore JA, Cramer SM. Evaluation of chemically selective displacer analogues for protein purification. Analytical Chemistry. 81: 6186-94. PMID 20337395 DOI: 10.1021/Ac900710F |
0.602 |
|
| 2009 |
Morrison CJ, Cramer SM. Characterization and design of chemically selective cationic displacers using a robotic high-throughput screen. Biotechnology Progress. 25: 825-33. PMID 19496161 DOI: 10.1002/btpr.159 |
0.615 |
|
| 2009 |
Barua S, Joshi A, Banerjee A, Matthews D, Sharfstein ST, Cramer SM, Kane RS, Rege K. Parallel synthesis and screening of polymers for nonviral gene delivery. Molecular Pharmaceutics. 6: 86-97. PMID 19102694 DOI: 10.1021/Mp800151J |
0.564 |
|
| 2009 |
Evans ST, Freed A, Cramer SM. Displacer concentration effects in displacement chromatography. Implications for trace solute detection. Journal of Chromatography. A. 1216: 79-85. PMID 19062027 DOI: 10.1016/j.chroma.2008.11.040 |
0.762 |
|
| 2009 |
Morrison CJ, Godawat R, McCallum SA, Garde S, Cramer SM. Mechanistic studies of displacer-protein binding in chemically selective displacement systems using NMR and MD simulations. Biotechnology and Bioengineering. 102: 1428-37. PMID 19030191 DOI: 10.1002/Bit.22170 |
0.616 |
|
| 2009 |
Chung WK, Hou Y, Freed A, Holstein M, Makhatadze GI, Cramer SM. Investigation of protein binding affinity and preferred orientations in ion exchange systems using a homologous protein library. Biotechnology and Bioengineering. 102: 869-81. PMID 18821632 DOI: 10.1002/Bit.22100 |
0.827 |
|
| 2008 |
Morrison CJ, Park SK, Simocko C, McCallum SA, Cramer SM, Moore JA. Synthesis and characterization of fluorescent displacers for online monitoring of displacement chromatography. Journal of the American Chemical Society. 130: 17029-37. PMID 19053488 DOI: 10.1021/Ja806279X |
0.584 |
|
| 2008 |
Vutukuru S, Kate SD, McCallum SA, Morrison CJ, Cramer SM, Kane RS. An affinity-based strategy for the design of selective displacers for the chromatographic separation of proteins Langmuir. 24: 6768-6773. PMID 18512879 DOI: 10.1021/la800581b |
0.615 |
|
| 2008 |
Liu J, Hilton ZA, Cramer SM. Chemically selective displacers for high-resolution protein separations in ion-exchange systems: effect of displacer-protein interactions. Analytical Chemistry. 80: 3357-64. PMID 18348543 DOI: 10.1021/ac702565p |
0.468 |
|
| 2007 |
Chen J, Yang T, Cramer SM. Prediction of protein retention times in gradient hydrophobic interaction chromatographic systems. Journal of Chromatography. A. 1177: 207-14. PMID 18048048 DOI: 10.1016/J.CHROMA.2007.11.003 |
0.495 |
|
| 2007 |
Yang T, Breneman CM, Cramer SM. Investigation of multi-modal high-salt binding ion-exchange chromatography using quantitative structure-property relationship modeling. Journal of Chromatography. A. 1175: 96-105. PMID 17991474 DOI: 10.1016/J.Chroma.2007.10.037 |
0.519 |
|
| 2007 |
Yang T, Sundling MC, Freed AS, Breneman CM, Cramer SM. Prediction of pH-dependent chromatographic behavior in ion-exchange systems. Analytical Chemistry. 79: 8927-39. PMID 17979253 DOI: 10.1021/ac071101j |
0.817 |
|
| 2007 |
Chen J, Cramer SM. Protein adsorption isotherm behavior in hydrophobic interaction chromatography. Journal of Chromatography. A. 1165: 67-77. PMID 17698076 DOI: 10.1016/j.chroma.2007.07.038 |
0.378 |
|
| 2007 |
Yang T, Malmquist G, Johansson BL, Maloisel JL, Cramer S. Evaluation of multi-modal high salt binding ion exchange materials. Journal of Chromatography. A. 1157: 171-7. PMID 17537448 DOI: 10.1016/j.chroma.2007.04.070 |
0.494 |
|
| 2007 |
Chen J, Luo Q, Breneman CM, Cramer SM. Classification of protein adsorption and recovery at low salt conditions in hydrophobic interaction chromatographic systems. Journal of Chromatography. A. 1139: 236-46. PMID 17126350 DOI: 10.1016/J.Chroma.2006.11.026 |
0.41 |
|
| 2007 |
Ghose S, Hubbard B, Cramer SM. Binding capacity differences for antibodies and Fc-fusion proteins on protein A chromatographic materials. Biotechnology and Bioengineering. 96: 768-79. PMID 16817242 DOI: 10.1002/bit.21044 |
0.709 |
|
| 2006 |
Teske CA, von Lieres E, Schröder M, Ladiwala A, Cramer SM, Hubbuch JJ. Competitive adsorption of labeled and native protein in confocal laser scanning microscopy. Biotechnology and Bioengineering. 95: 58-66. PMID 16752371 DOI: 10.1002/Bit.20940 |
0.809 |
|
| 2006 |
Ghose S, Hubbard B, Cramer SM. Evaluation and comparison of alternatives to Protein A chromatography Mimetic and hydrophobic charge induction chromatographic stationary phases. Journal of Chromatography. A. 1122: 144-52. PMID 16750212 DOI: 10.1016/j.chroma.2006.04.083 |
0.711 |
|
| 2006 |
Ladiwala A, Xia F, Luo Q, Breneman CM, Cramer SM. Investigation of protein retention and selectivity in HIC systems using quantitative structure retention relationship models. Biotechnology and Bioengineering. 93: 836-50. PMID 16276531 DOI: 10.1002/Bit.20771 |
0.845 |
|
| 2006 |
Ghose S, Allen M, Hubbard B, Brooks C, Cramer SM. Antibody variable region interactions with Protein A: implications for the development of generic purification processes. Biotechnology and Bioengineering. 92: 665-73. PMID 16206278 DOI: 10.1002/bit.20729 |
0.816 |
|
| 2005 |
Rege K, Ladiwala A, Hu S, Breneman CM, Dordick JS, Cramer SM. Investigation of DNA-binding properties of an aminoglycoside-polyamine library using quantitative structure-activity relationship (QSAR) models. Journal of Chemical Information and Modeling. 45: 1854-63. PMID 16309293 DOI: 10.1021/Ci050082G |
0.797 |
|
| 2005 |
Rege K, Ladiwala A, Cramer SM. Multidimensional high-throughput screening of displacers. Analytical Chemistry. 77: 6818-27. PMID 16255578 DOI: 10.1021/Ac050314A |
0.808 |
|
| 2005 |
Ladiwala A, Rege K, Breneman CM, Cramer SM. A priori prediction of adsorption isotherm parameters and chromatographic behavior in ion-exchange systems. Proceedings of the National Academy of Sciences of the United States of America. 102: 11710-5. PMID 16081542 DOI: 10.1073/Pnas.0408769102 |
0.82 |
|
| 2005 |
Xia F, Nagrath D, Cramer SM. Effect of pH changes on water release values in hydrophobic interaction chromatographic systems. Journal of Chromatography. A. 1079: 229-35. PMID 16038309 DOI: 10.1016/J.Chroma.2005.04.005 |
0.729 |
|
| 2005 |
Jindal R, Plawsky JL, Cramer SM. Selective filling for patterning in microfluidic channels. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 4458-63. PMID 16032860 DOI: 10.1021/la047463t |
0.707 |
|
| 2005 |
Ghose S, Hubbard B, Cramer SM. Protein interactions in hydrophobic charge induction chromatography (HCIC). Biotechnology Progress. 21: 498-508. PMID 15801790 DOI: 10.1021/bp049712+ |
0.698 |
|
| 2005 |
Jindal R, Cramer SM. On-chip electrochromatography using sol-gel immobilized stationary phase with UV absorbance detection. Journal of Chromatography. A. 1044: 277-85. PMID 15354449 DOI: 10.1016/j.chroma.2004.05.065 |
0.64 |
|
| 2004 |
Rege K, Hu S, Moore JA, Dordick JS, Cramer SM. Chemoenzymatic synthesis and high-throughput screening of an aminoglycoside-polyamine library: identification of high-affinity displacers and DNA-binding ligands. Journal of the American Chemical Society. 126: 12306-15. PMID 15453764 DOI: 10.1021/Ja049437N |
0.645 |
|
| 2004 |
Xia F, Nagrath D, Garde S, Cramer SM. Evaluation of selectivity changes in HIC systems using a preferential interaction based analysis. Biotechnology and Bioengineering. 87: 354-63. PMID 15281110 DOI: 10.1002/Bit.20120 |
0.744 |
|
| 2004 |
Ghose S, Nagrath D, Hubbard B, Brooks C, Cramer SM. Use and optimization of a dual-flowrate loading strategy to maximize throughput in protein-a affinity chromatography. Biotechnology Progress. 20: 830-40. PMID 15176889 DOI: 10.1021/Bp0342654 |
0.783 |
|
| 2004 |
Rege K, Ladiwala A, Tugcu N, Breneman CM, Cramer SM. Parallel screening of selective and high-affinity displacers for proteins in ion-exchange systems. Journal of Chromatography. A. 1033: 19-28. PMID 15072287 DOI: 10.1016/J.Chroma.2003.12.071 |
0.821 |
|
| 2003 |
Tugcu N, Ladiwala A, Breneman CM, Cramer SM. Identification of chemically selective displacers using parallel batch screening experiments and quantitative structure efficacy relationship models. Analytical Chemistry. 75: 5806-16. PMID 14588021 DOI: 10.1021/Ac0341564 |
0.818 |
|
| 2003 |
Tugcu N, Song M, Breneman CM, Sukumar N, Bennett KP, Cramer SM. Prediction of the effect of mobile-phase salt type on protein retention and selectivity in anion exchange systems. Analytical Chemistry. 75: 3563-72. PMID 14570211 DOI: 10.1021/Ac0263519 |
0.787 |
|
| 2003 |
Xia F, Nagrath D, Cramer SM. Modeling of adsorption in hydrophobic interaction chromatography systems using a preferential interaction quadratic isotherm. Journal of Chromatography. A. 989: 47-54. PMID 12641281 DOI: 10.1016/S0021-9673(02)02047-2 |
0.716 |
|
| 2003 |
Sunasara KM, Xia F, Gronke RS, Cramer SM. Application of hydrophobic interaction displacement chromatography for an industrial protein purification. Biotechnology and Bioengineering. 82: 330-9. PMID 12599260 DOI: 10.1002/bit.10582 |
0.804 |
|
| 2002 |
Song M, Breneman CM, Bi J, Sukumar N, Bennett KP, Cramer S, Tugcu N. Prediction of protein retention times in anion-exchange chromatography systems using support vector regression. Journal of Chemical Information and Computer Sciences. 42: 1347-57. PMID 12444731 DOI: 10.1021/Ci025580T |
0.773 |
|
| 2002 |
Mazza CB, Rege K, Breneman CM, Sukumar N, Dordick JS, Cramer SM. High-throughput screening and quantitative structure-efficacy relationship models of potential displacer molecules for ion-exchange systems. Biotechnology and Bioengineering. 80: 60-72. PMID 12209787 DOI: 10.1002/Bit.10343 |
0.808 |
|
| 2002 |
Tugcu N, Bae SS, Moore JA, Cramer SM. Stationary phase effects on the dynamic affinity of low-molecular-mass displacers. Journal of Chromatography. A. 954: 127-35. PMID 12058897 DOI: 10.1016/S0021-9673(02)00164-4 |
0.768 |
|
| Show low-probability matches. |
