Lawrence Stanley Weiler, Ph.D. - Related publications

Affiliations: 
Chemistry University of British Columbia, Vancouver, Vancouver, BC, Canada 
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Silva DR, Silla JM, Santos LA, da Cunha EFF, Freitas MP. The Role of Intramolecular Interactions on the Bioactive Conformation of Epinephrine. Molecular Informatics. PMID 30945816 DOI: 10.1002/minf.201800167   
2019 Gibbons D, Flanagan KJ, Pounot L, Senge MO. Structure and conformation of photosynthetic pigments and related compounds. 15. Conformational analysis of chlorophyll derivatives - implications for hydroporphyrins in vivo. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. PMID 30964476 DOI: 10.1039/c8pp00500a   
2019 Taechalertpaisarn J, Lyu RL, Arancillo M, Lin CM, Perez LM, Ioerger TR, Burgess K. Correlations between secondary structure- and protein-protein interface-mimicry: the interface mimicry hypothesis. Organic & Biomolecular Chemistry. PMID 30847453 DOI: 10.1039/c9ob00204a   
2019 Brodie NI, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH. Conformational ensemble of native α-synuclein in solution as determined by short-distance crosslinking constraint-guided discrete molecular dynamics simulations. Plos Computational Biology. 15: e1006859. PMID 30917118 DOI: 10.1371/journal.pcbi.1006859   
2019 Gole B, Kauffmann B, Maurizot V, Huc I, Ferrand Y. Light-Controlled Conformational Switch of an Aromatic Oligoamide Foldamer. Angewandte Chemie (International Ed. in English). PMID 30957386 DOI: 10.1002/anie.201902378   
2019 Bayse CA, Pollard DB. Conformation dynamics of cyclic disulfides and selenosulfides in CXXC(U) (X = Gly, Ala) tetrapeptide redox motifs. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3160. PMID 30873692 DOI: 10.1002/psc.3160   
2019 Schröder DC, Kracker O, Fröhr T, Góra J, Jewginski M, Nieß A, Antes I, Latajka R, Marion A, Sewald N. 1,4-Disubstituted 1-1,2,3-Triazole Containing Peptidotriazolamers: A New Class of Peptidomimetics With Interesting Foldamer Properties. Frontiers in Chemistry. 7: 155. PMID 30972322 DOI: 10.3389/fchem.2019.00155   
2019 Modi V, Dunbrack RL. Defining a new nomenclature for the structures of active and inactive kinases. Proceedings of the National Academy of Sciences of the United States of America. PMID 30867294 DOI: 10.1073/pnas.1814279116   
2019 Arrata I, Grison CM, Coubrough HM, Prabhakaran P, Little MA, Tomlinson DC, Webb ME, Wilson AJ. Control of conformation in α-helix mimicking aromatic oligoamide foldamers through interactions between adjacent side-chains. Organic & Biomolecular Chemistry. PMID 30938392 DOI: 10.1039/c9ob00123a   
2019 Zhu XL, Z'hang R, Wu QY, Song YJ, Wang YX, Yang JF, Yang GF. Natural Product Neopeltolide as A Cytochrome bc1 Complex Inhibitor: Mechanism of Action and Structural Modification. Journal of Agricultural and Food Chemistry. PMID 30794394 DOI: 10.1021/acs.jafc.8b06195   
2019 Bansal A, Karanth NM, Demeler B, Schindelin H, Sarma SP. Crystallographic structures of IlvN●Val / Ile complexes: Conformational selectivity for feedback inhibition of AHASs. Biochemistry. PMID 30887800 DOI: 10.1021/acs.biochem.9b00050   
2019 Chaudhary M, Kumar N, Baldi A, Chandra R, Babu MA, Madan J. 4-Bromo 4'-chloro pyrazoline analog of curcumin augmented anticancer activity against Human cervical cancer, HeLa cells: In-silico guided analysis, synthesis and in-vitro cytotoxicity. Journal of Biomolecular Structure & Dynamics. 1-40. PMID 30957694 DOI: 10.1080/07391102.2019.1604266   
2019 Bari KJ, Sharma S, Chary KVR. Conformational dynamics study on human γS-crystallin as an efficient route to childhood blindness. Biochemical and Biophysical Research Communications. PMID 30827504 DOI: 10.1016/j.bbrc.2019.02.124   
2019 Fischer T, Koulas SM, Tsagkarakou AS, Kyriakis E, Stravodimos GA, Skamnaki VT, Liggri PGV, Zographos SE, Riedl R, Leonidas DD. High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl--acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors. Molecules (Basel, Switzerland). 24. PMID 30987252 DOI: 10.3390/molecules24071322   
2019 Wang W, Zhang Y, Wang L, Jing Q, Wang X, Xi X, Zhao X, Wang H. Molecular structure of thermostable and zinc-ion-binding γ-class carbonic anhydrases. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 30895492 DOI: 10.1007/s10534-019-00190-8   
2019 Li Z, Wu D, Zhan B, Hu X, Gan J, Ji C, Li J. Structural insights into the complex of trigger factor chaperone and ribosomal protein S7 from Mycobacterium tuberculosis. Biochemical and Biophysical Research Communications. PMID 30928093 DOI: 10.1016/j.bbrc.2019.03.166   
2019 Blinov N, Wishart DS, Kovalenko A. Solvent Composition Effects on Structural Properties of the A β42 Monomer From the 3D-RISM-KH Molecular Theory of Solvation. The Journal of Physical Chemistry. B. PMID 30811210 DOI: 10.1021/acs.jpcb.9b00480   
2019 Peng Z, Guo X, Xu W, Li J, Deng P, Xiao X, Feng W, Yuan L. Strong positive allosteric cooperativity in ternary complexes based on hydrogen-bonded aromatic amide macrocycles. Chemical Communications (Cambridge, England). PMID 30951049 DOI: 10.1039/c9cc00925f   
2019 Dickerhoff J, Onel B, Chen L, Chen Y, Yang D. Solution Structure of a Promoter G-Quadruplex with 1:6:1 Loop Length. Acs Omega. 4: 2533-2539. PMID 30842981 DOI: 10.1021/acsomega.8b03580   
2019 Pandey P, Meena NK, Prakash A, Kumar V, Lynn AM, Ahmad F. Characterization of Heterogeneous Intermediate Ensembles on the Guanidinium Chloride-induced Unfolding Pathway of β-lactoglobulin. Journal of Biomolecular Structure & Dynamics. 1-17. PMID 30880641 DOI: 10.1080/07391102.2019.1593245   
2019 Samuels ER, Sevrioukova I. Structure-activity relationships of rationally designed ritonavir analogs: Impact of side-group stereochemistry, head-group spacing, and backbone composition on the interaction with CYP3A4. Biochemistry. PMID 30912932 DOI: 10.1021/acs.biochem.9b00156   
2019 Spencer RK, Butterfoss GL, Edison JR, Eastwood JR, Whitelam S, Kirshenbaum K, Zuckermann RN. Stereochemistry of polypeptoid chain configurations. Biopolymers. e23266. PMID 30835823 DOI: 10.1002/bip.23266   
2019 Roe LT, Pelton JG, Edison JR, Butterfoss GL, Tresca BW, LaFaye BA, Whitelam S, Wemmer DE, Zuckermann RN. Unconstrained peptoid tetramer exhibits a predominant conformation in aqueous solution. Biopolymers. e23267. PMID 30835821 DOI: 10.1002/bip.23267   
2019 Fan S, Wang R, Li C, Bai L, Zhao YL, Shi T. Insight into Structural Characteristics of Protein-Substrate Interaction in Pimaricin Thioesterase. International Journal of Molecular Sciences. 20. PMID 30781619 DOI: 10.3390/ijms20040877   
2019 Dolenc J, van Gunsteren WF, Prota AE, Steinmetz MO, Missimer JH. Conformational Properties of the Chemotherapeutic Drug Analogue Epothilone A: How to Model a Flexible Protein Ligand Using Scarcely Available Experimental Data. Journal of Chemical Information and Modeling. PMID 30855963 DOI: 10.1021/acs.jcim.9b00171   
2019 Mohan R, Venugopal S. Molecular Binding and Simulation Studies of Staphylococcus aureus Superantigens with Flavonoid Compounds. Infectious Disorders Drug Targets. PMID 30727923 DOI: 10.2174/1871526519666190207092307   
2019 Wang Y, He Y, Yu Z, Gao J, Ten Brinck S, Slebodnick C, Fahs GB, Zanelotti CJ, Hegde M, Moore RB, Ensing B, Dingemans TJ, Qiao R, Madsen LA. Double helical conformation and extreme rigidity in a rodlike polyelectrolyte. Nature Communications. 10: 801. PMID 30778067 DOI: 10.1038/s41467-019-08756-3   
2019 Sawada T, Saito A, Tamiya K, Shimokawa K, Hisada Y, Fujita M. Metal-peptide rings form highly entangled topologically inequivalent frameworks with the same ring- and crossing-numbers. Nature Communications. 10: 921. PMID 30796223 DOI: 10.1038/s41467-019-08879-7   
2019 Sun L, Xie X, Weng W, Jin H. Structural and mechanistic insights into modified G-quadruplex thrombin-binding DNA aptamers. Biochemical and Biophysical Research Communications. PMID 30992128 DOI: 10.1016/j.bbrc.2019.04.025   
2019 Hu Y, Jia X, Lu Z, Han L. Characterization of crystal structure and key residues of Aspergillus fumigatus nucleoside diphosphate kinase. Biochemical and Biophysical Research Communications. PMID 30773256 DOI: 10.1016/j.bbrc.2019.01.126   
2019 Basciu A, Malloci G, Pietrucci F, Bonvin AMJJ, Vargiu AV. Holo-like and Druggable Protein Conformations from Enhanced Sampling of Binding Pocket Volume and Shape. Journal of Chemical Information and Modeling. PMID 30883122 DOI: 10.1021/acs.jcim.8b00730   
2019 Kaur A, Gourav, Kumar S, Jaiswal N, Vashisht A, Kumar D, Gahlay GK, Mithu VS. NMR Characterization of Conformational Fluctuations and Non-covalent Interactions of SUMO protein from Drosophila melanogaster (dSmt3). Proteins. PMID 30958586 DOI: 10.1002/prot.25690   
2019 Mohanty P, Bhatnagar S. In Silico Screening to Identify Inhibitors of Growth Factor Receptor 2-Focal Adhesion Kinase Interaction for Therapeutic Treatment of Pathological Cardiac Hypertrophy. Assay and Drug Development Technologies. 17: 58-67. PMID 30869527 DOI: 10.1089/adt.2018.887   
2019 Codina N, Hilton D, Zhang C, Chakroun N, Ahmad SS, Perkins SJ, Dalby PA. An Expanded Conformation of an Antibody Fab Region by X-Ray Scattering, Molecular Dynamics and smFRET Identifies an Aggregation Mechanism. Journal of Molecular Biology. PMID 30776431 DOI: 10.1016/j.jmb.2019.02.009   
2019 Aletti AB, Miljkovic A, Toma L, Bruno R, Armentano D, Gunnlaugsson T, Bergamaschi G, Amendola V. Halide-Controlled Extending-Shrinking Motion of a Covalent Cage. The Journal of Organic Chemistry. PMID 30880393 DOI: 10.1021/acs.joc.9b00219   
2019 Shakirov T, Paul W. Folded alkane chains and the emergence of the lamellar crystal. The Journal of Chemical Physics. 150: 084903. PMID 30823774 DOI: 10.1063/1.5087640   
2019 Orellana L, Gustavsson J, Bergh C, Yoluk O, Lindahl E. eBDIMS server: protein transition pathways with ensemble analysis in 2D-motion spaces. Bioinformatics (Oxford, England). PMID 30838394 DOI: 10.1093/bioinformatics/btz104   
2019 Ball KA, Chan LM, Stanley DJ, Tierney E, Thapa S, Ta HM, Burton L, Binning JM, Jacobson MP, Gross JD. Conformational Dynamics of the HIV-Vif Protein Complex. Biophysical Journal. PMID 30961890 DOI: 10.1016/j.bpj.2019.03.014   
2019 Schneider HJ. Strain effects determine the performance of artificial allosteric systems: calixarenes as models. Chemical Communications (Cambridge, England). 55: 3433-3444. PMID 30843901 DOI: 10.1039/c9cc00573k   
2019 Cho HJ, Lee HJ, Cho HY, Park JW, Lee DS, Lee HS, Kwon OS, Kang BS. Structural basis for substrate binding to human pyridoxal 5'-phosphate phosphatase/chronophin by a conformational change. International Journal of Biological Macromolecules. PMID 30914363 DOI: 10.1016/j.ijbiomac.2019.03.097   
2019 Kwon S, Park HH. Crystal structure of the apo form of a β-transaminase from Mesorhizobium sp. strain LUK. Protein Science : a Publication of the Protein Society. PMID 30805955 DOI: 10.1002/pro.3594   
2019 Ali S, Khan FI, Mohammad T, Lan D, Hassan MI, Wang Y. Identification and Evaluation of Inhibitors of Lipase from using Virtual High-Throughput Screening and Molecular Dynamics Studies. International Journal of Molecular Sciences. 20. PMID 30781686 DOI: 10.3390/ijms20040884   
2019 Wei D, Yang J, Jiang MQ, Dai LH, Wang YJ, Dyre JC, Douglass I, Harrowell P. Assessing the utility of structure in amorphous materials. The Journal of Chemical Physics. 150: 114502. PMID 30902013 DOI: 10.1063/1.5064531   
2019 Bari KJ, Sharma S, Chary KVR. Structure of G57W mutant of human γS-crystallin and its involvement in cataract formation. Journal of Structural Biology. PMID 30769148 DOI: 10.1016/j.jsb.2019.02.003   
2019 Schwartz M, Perrot T, Morel-Rouhier M, Mulliert G, Gelhaye E, Didierjean C, Favier F. The structure of Trametes versicolor Glutathione Transferase Omega 3S bound to its conjugation product GS-PEITC reveals plasticity of its active site. Protein Science : a Publication of the Protein Society. PMID 30972861 DOI: 10.1002/pro.3620   
2019 Mezzetti A, Alexandre MTA, Thurotte A, Wilson A, Gwizdala M, Kirilovsky D. Two-Step Structural Changes in Orange Carotenoid Protein Photoactivation Revealed by Time Resolved FTIR Spectroscopy. The Journal of Physical Chemistry. B. PMID 30895789 DOI: 10.1021/acs.jpcb.9b01242   
2019 Gulati S, Palczewski K, Engel A, Stahlberg H, Kovacik L. Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases. Science Advances. 5: eaav4322. PMID 30820458 DOI: 10.1126/sciadv.aav4322   
2019 Inaba S, Shiota A, Yoshida T, Oda M. Protein structure and analysis site-specific observation of the conformational change of a protein with N-labeled Tyr residues using NMR. Analytical Biochemistry. PMID 30910701 DOI: 10.1016/j.ab.2019.03.009   
2019 Li J, Feng H, Liu R, Ding G, Si H, He W, Sun Z. The computational and experimental studies on a 1, 2, 3-triazole compound and its special binding to three kinds of blood proteins. Journal of Biomolecular Structure & Dynamics. 1-17. PMID 30909827 DOI: 10.1080/07391102.2019.1598498   
2019 Mirdha L, Chakraborty H. Characterization of structural conformers of κ-casein utilizing fluorescence spectroscopy. International Journal of Biological Macromolecules. 131: 89-96. PMID 30851321 DOI: 10.1016/j.ijbiomac.2019.03.040