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278 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pannkuk EL, Dorville NAS, Dzal YA, Fletcher QE, Norquay KJO, Willis CKR, Fornace AJ, Laiakis EC. Hepatic lipid signatures of little brown bats (Myotis lucifugus) and big brown bats (Eptesicus fuscus) at early stages of white-nose syndrome. Scientific Reports. 11: 11581. PMID 34078939 DOI: 10.1038/s41598-021-90828-w  0.6
2021 Laiakis EC, Canadell MP, Grilj V, Harken AD, Garty GY, Brenner DJ, Smilenov L, Fornace AJ. Small Molecule Responses to Sequential Irradiation with Neutrons and Photons for Biodosimetry Applications: An Initial Assessment. Radiation Research. PMID 33857313 DOI: 10.1667/RADE-20-00032.1  0.6
2021 Laiakis EC, Shuryak I, Deziel A, Wang YW, Barnette BL, Yu Y, Ullrich RL, Fornace AJ, Emmett MR. Effects of Low Dose Space Radiation Exposures on the Splenic Metabolome. International Journal of Molecular Sciences. 22. PMID 33802822 DOI: 10.3390/ijms22063070  0.6
2020 Garty G, Xu Y, Johnson GW, Smilenov LB, Joseph SK, Pujol-Canadell M, Turner HC, Ghandhi SA, Wang Q, Shih R, Morton RC, Cuniberti DE, Morton SR, Bueno-Beti C, Morgan TL, ... ... Fornace AJ, et al. VADER: a variable dose-rate external Cs irradiator for internal emitter and low dose rate studies. Scientific Reports. 10: 19899. PMID 33199728 DOI: 10.1038/s41598-020-76941-2  0.6
2020 Li HH, Lin YT, Laiakis EC, Goudarzi M, Weber W, Fornace AJ. Serum Metabolomic Alterations Associated with Cesium-137 Internal Emitter Delivered in Various Dose Rates. Metabolites. 10. PMID 32629836 DOI: 10.3390/Metabo10070270  0.6
2020 Pannkuk EL, Laiakis EC, Ake P, Strawn SJ, Wang YW, Fornace AJ. Effects of Genetic Variation on Urinary Small Molecule Signatures of Mice after Exposure to Ionizing Radiation: A Study of p53 Deficiency. Metabolites. 10. PMID 32521675 DOI: 10.3390/Metabo10060234  0.6
2020 Laiakis EC, McCart EA, Deziel A, Rittase WB, Bouten RM, Jha J, Wilkins WL, Day RM, Fornace AJ. Effect of 3,3'-diindolylmethane on Pulmonary Injury Following Thoracic Irradiation in CBA mice. Health Physics. PMID 32384373 DOI: 10.1097/Hp.0000000000001257  0.6
2020 Suman S, Shuryak I, Kallakury B, Brenner DJ, Fornace AJ, Johnson MD, Datta K. Protons show greater relative biological effectiveness for mammary tumorigenesis with higher ERα and HER2 positive tumors relative to γ-rays in APC mice. International Journal of Radiation Oncology, Biology, Physics. PMID 32036005 DOI: 10.1016/J.Ijrobp.2020.01.031  0.32
2020 Vera NB, Coy SL, Laiakis EC, Fornace AJ, Clasquin M, Barker CA, Pfefferkorn JA, Vouros P. Quantitation of Urinary Acylcarnitines by DMS-MS/MS Uncovers the Effects of Total Body Irradiation in Cancer Patients. Journal of the American Society For Mass Spectrometry. PMID 32013416 DOI: 10.1021/Jasms.9B00076  0.6
2019 Laiakis EC, Nishita D, Bujold K, Jayatilake MM, Bakke J, Gahagen J, Authier S, Chang P, Fornace AJ. Salivary metabolomics of total body irradiated non-human primates reveals long term normal tissue responses to radiation. International Journal of Radiation Oncology, Biology, Physics. PMID 31352081 DOI: 10.1016/J.Ijrobp.2019.07.017  0.6
2019 Pannkuk EL, Laiakis EC, Girgis M, Dowd SE, Dhungana S, Nishita D, Bujold K, Bakke J, Gahagen J, Authier S, Chang PY, Fornace AJ. Temporal Effects on Radiation Responses in Nonhuman Primates: Identification of Biofluid Small Molecule Signatures by Gas Chromatography⁻Mass Spectrometry Metabolomics. Metabolites. 9. PMID 31096611 DOI: 10.3390/Metabo9050098  0.6
2019 Taraboletti A, Goudarzi M, Kabir A, Moon BH, Laiakis EC, Lacombe J, Ake P, Shoishiro S, Brenner D, Fornace AJ, Zenhausern F. Fabric Phase Sorptive Extraction - A metabolomic pre-processing approach for ionizing radiation exposure assessment. Journal of Proteome Research. PMID 31090424 DOI: 10.1021/Acs.Jproteome.9B00142  0.6
2019 Pannkuk EL, Laiakis EC, Singh VK, Fornace AJ. Author Correction: Lipidomic Signatures of Nonhuman Primates with Radiation-Induced Hematopoietic Syndrome. Scientific Reports. 9: 6878. PMID 31053740 DOI: 10.1038/S41598-019-42491-5  0.6
2019 Mukherjee S, Laiakis EC, Fornace AJ, Amundson SA. Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease. Bmc Genomics. 20: 329. PMID 31046668 DOI: 10.1186/S12864-019-5689-Y  0.6
2019 Laiakis EC, Canadell MP, Grilj V, Harken AD, Garty GY, Astarita G, Brenner DJ, Smilenov L, Fornace AJ. Serum lipidomic analysis from mixed neutron/X-ray radiation fields reveals a hyperlipidemic and pro-inflammatory phenotype. Scientific Reports. 9: 4539. PMID 30872747 DOI: 10.1038/S41598-019-41083-7  0.6
2019 Pannkuk EL, Laiakis EC, Gill K, Jain SK, Mehta KY, Nishita D, Bujold K, Bakke J, Gahagen J, Authier S, Chang P, Fornace AJ. Liquid Chromatography - Mass Spectrometry based Metabolomics of Nonhuman Primates after 4 Gy Total Body Radiation Exposure: Global Effects and Targeted Panels. Journal of Proteome Research. PMID 30843397 DOI: 10.1021/Acs.Jproteome.9B00101  0.6
2018 Pannkuk EL, Laiakis EC, Garcia M, Fornace AJ, Singh VK. Nonhuman Primates with Acute Radiation Syndrome: Results from a Global Serum Metabolomics Study after 7.2 Gy Total-Body Irradiation. Radiation Research. PMID 30183511 DOI: 10.1667/Rr15167.1  0.6
2018 Laiakis EC, Mak TD, Strawn SJ, Wang YW, Moon BH, Ake P, Fornace AJ. Global metabolomic responses in urine from atm deficient mice in response to LD gamma irradiation doses. Environmental and Molecular Mutagenesis. PMID 30095186 DOI: 10.1002/Em.22202  0.6
2018 Pannkuk EL, Laiakis EC, Fornace AJ, Fatanmi OO, Singh VK. A Metabolomic Serum Signature from Nonhuman Primates Treated with a Radiation Countermeasure, Gamma-tocotrienol, and Exposed to Ionizing Radiation. Health Physics. 115: 3-11. PMID 29787425 DOI: 10.1097/Hp.0000000000000776  0.6
2018 Kumar MAS, Laiakis EC, Ghandhi SA, Morton SR, Fornace AJ, Amundson SA. Gene Expression in Parp1 Deficient Mice Exposed to a Median Lethal Dose of Gamma Rays. Radiation Research. PMID 29746213 DOI: 10.1667/Rr14990.1  0.6
2018 Chen Z, Coy SL, Pannkuk EL, Laiakis EC, Fornace AJ, Vouros P. Differential Mobility Spectrometry-Mass Spectrometry (DMS-MS) in Radiation Biodosimetry: Rapid and High-Throughput Quantitation of Multiple Radiation Biomarkers in Nonhuman Primate Urine. Journal of the American Society For Mass Spectrometry. PMID 29736597 DOI: 10.1007/S13361-018-1977-Z  0.6
2018 Vera NB, Chen Z, Pannkuk E, Laiakis EC, Fornace AJ, Erion DM, Coy SL, Pfefferkorn JA, Vouros P. Differential Mobility Spectrometry (DMS) Reveals the Elevation of Urinary Acetylcarnitine in Non-Human Primates (NHPs) Exposed to Radiation. Journal of Mass Spectrometry : Jms. PMID 29596720 DOI: 10.1002/Jms.4085  0.6
2018 Rudqvist N, Laiakis EC, Ghandhi SA, Kumar S, Knotts JD, Chowdhury M, Fornace AJ, Amundson SA. Global Gene Expression Response in Mouse Models of DNA Repair Deficiency after Gamma Irradiation. Radiation Research. PMID 29351057 DOI: 10.1667/Rr14862.1  0.6
2017 Li D, Chen R, Wang YW, Fornace AJ, Li HH. Prior Irradiation Results in Elevated Programmed Cell Death Protein 1 (PD-1) in T Cells. International Journal of Radiation Biology. 1-18. PMID 29108460 DOI: 10.1080/09553002.2017.1400192  0.4
2017 Pannkuk EL, Laiakis EC, Singh VK, Fornace AJ. Lipidomic Signatures of Nonhuman Primates with Radiation-Induced Hematopoietic Syndrome. Scientific Reports. 7: 9777. PMID 28852188 DOI: 10.1038/S41598-017-10299-W  0.6
2017 Laiakis EC, Pannkuk EL, Chauthe SK, Wang YW, Lian M, Mak TD, Barker CA, Astarita G, Fornace AJ. A serum small molecule biosignature of radiation exposure from total body irradiated patients. Journal of Proteome Research. PMID 28825479 DOI: 10.1021/Acs.Jproteome.7B00468  0.6
2017 Suman S, Kumar S, Moon BH, Fornace AJ, Kallakury BVS, Datta K. Increased Transgenerational Intestinal Tumorigenesis in Offspring of Ionizing Radiation Exposed Parent APC(1638N/+) Mice. Journal of Cancer. 8: 1769-1773. PMID 28819373 DOI: 10.7150/Jca.17803  0.4
2017 Suman S, Kumar S, Moon BH, Fornace AJ, Datta K. Low and high dose rate heavy ion radiation-induced intestinal and colonic tumorigenesis in APC(1638N/+) mice. Life Sciences in Space Research. 13: 45-50. PMID 28554509 DOI: 10.1016/J.Lssr.2017.04.003  0.4
2017 Laiakis EC, Wang YW, Young EF, Harken AD, Xu Y, Smilenov L, Garty GY, Brenner DJ, Fornace AJ. Metabolic Dysregulation after Neutron Exposures Expected from an Improvised Nuclear Device. Radiation Research. PMID 28475424 DOI: 10.1667/Rr14656.1  0.6
2017 Pannkuk EL, Laiakis EC, Authier S, Wong K, Fornace AJ. Gas chromatography/mass spectrometry metabolomics of urine and serum from nonhuman primates exposed to ionizing radiation: Impacts on the tricarboxylic acid cycle and protein metabolism. Journal of Proteome Research. PMID 28351153 DOI: 10.1021/Acs.Jproteome.7B00064  0.6
2017 Shuryak I, Fornace AJ, Datta K, Suman S, Kumar S, Sachs RK, Brenner DJ. Scaling Human Cancer Risks from Low LET to High LET when Dose-Effect Relationships are Complex. Radiation Research. PMID 28218889 DOI: 10.1667/Rr009Cc.1  0.32
2017 Pannkuk EL, Fornace AJ, Laiakis EC. Metabolomic applications in radiation biodosimetry: exploring radiation effects through small molecules. International Journal of Radiation Biology. 1-26. PMID 28067089 DOI: 10.1080/09553002.2016.1269218  0.6
2017 Laiakis EC, Pannkuk EL, Chauthe S, Wang Y, Lian M, Mak TD, Barker CA, Astarita G, Fornace AJ. Abstract 2506: Untargeted and targeted multiplatform metabolomic and lipidomic approaches for monitoring biological effects in serum from total body irradiated humans Cancer Research. 77: 2506-2506. DOI: 10.1158/1538-7445.Am2017-2506  0.6
2016 Pannkuk EL, Laiakis EC, Authier S, Wong K, Fornace AJ. Targeted Metabolomics of Nonhuman Primate Serum after Exposure to Ionizing Radiation: Potential Tools for High-throughput Biodosimetry. Rsc Advances. 6: 51192-51202. PMID 28367319 DOI: 10.1039/C6Ra07757A  0.6
2016 Pannkuk EL, Laiakis EC, Mak TD, Astarita G, Authier S, Wong K, Fornace AJ. A Lipidomic and Metabolomic Serum Signature from Nonhuman Primates Exposed to Ionizing Radiation. Metabolomics : Official Journal of the Metabolomic Society. 12. PMID 28220056 DOI: 10.1007/S11306-016-1010-0  0.6
2016 Jacobs JP, Goudarzi M, Singh N, Tong M, McHardy IH, Ruegger P, Asadourian M, Moon BH, Ayson A, Borneman J, McGovern DP, Fornace AJ, Braun J, Dubinsky M. A Disease-Associated Microbial and Metabolomics State in Relatives of Pediatric Inflammatory Bowel Disease Patients. Cellular and Molecular Gastroenterology and Hepatology. 2: 750-766. PMID 28174747 DOI: 10.1016/J.Jcmgh.2016.06.004  0.6
2016 Jacobs JP, Lin L, Goudarzi M, Ruegger P, McGovern DP, Fornace AJ, Borneman J, Xia L, Braun J. Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency. Gut Microbes. 0. PMID 27874308 DOI: 10.1080/19490976.2016.1257469  0.6
2016 Chen R, Wang YW, Fornace AJ, Li HH. Impairment of the Intrinsic Capability of Th1 Polarization in Irradiated Mice: A Close Look at the Imbalanced Th1/Th2 Response after Irradiation. Radiation Research. PMID 27849436 DOI: 10.1667/Rr14401.1  0.4
2016 Koga T, Yao PL, Goudarzi M, Murray IA, Balandaram G, Gonzalez FJ, Perdew GH, Fornace AJ, Peters JM. Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-Activated Receptor-β/δ Modulation of SP1 Promoter Occupancy. The Journal of Biological Chemistry. PMID 27765815 DOI: 10.1074/Jbc.M116.755447  0.6
2016 Goudarzi M, Mak TD, Jacobs JP, Moon BH, Strawn SJ, Braun J, Brenner DJ, Fornace AJ, Li HH. An Integrated Multi-Omic Approach to Assess Radiation Injury on the Host-Microbiome Axis. Radiation Research. PMID 27512828 DOI: 10.1667/Rr14306.1  0.6
2016 Chen Z, Coy SL, Pannkuk EL, Laiakis EC, Hall AB, Fornace AJ, Vouros P. Rapid and High-Throughput Detection and Quantitation of Radiation Biomarkers in Human and Nonhuman Primates by Differential Mobility Spectrometry-Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 27392730 DOI: 10.1007/S13361-016-1438-5  0.6
2016 Laiakis EC, Strawn SJ, Brenner DJ, Fornace AJ. Assessment of Saliva as a Potential Biofluid for Biodosimetry: A Pilot Metabolomics Study in Mice. Radiation Research. PMID 27332953 DOI: 10.1667/Rr14433.1  0.6
2016 Goudarzi M, Chauthe S, Strawn SJ, Weber WM, Brenner DJ, Fornace AJ. Quantitative Metabolomic Analysis of Urinary Citrulline and Calcitroic Acid in Mice after Exposure to Various Types of Ionizing Radiation. International Journal of Molecular Sciences. 17. PMID 27213362 DOI: 10.3390/Ijms17050782  0.6
2016 Kwon OS, Kim KT, Lee E, Kim M, Choi SH, Li H, Fornace AJ, Cho JH, Lee YS, Lee JS, Lee YJ, Cha HJ. Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response. Plos One. 11: e0154942. PMID 27171163 DOI: 10.1371/Journal.Pone.0154942  0.48
2016 Cheema AK, Maier I, Dowdy T, Wang Y, Singh R, Ruegger PM, Borneman J, Fornace AJ, Schiestl RH. Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis. Plos One. 11: e0151190. PMID 27073845 DOI: 10.1371/Journal.Pone.0151190  0.48
2016 Laiakis EC, Pannkuk EL, Diaz-Rubio ME, Wang YW, Mak TD, Simbulan-Rosenthal CM, Brenner DJ, Fornace AJ. Implications of genotypic differences in the generation of a urinary metabolomics radiation signature. Mutation Research. PMID 27040378 DOI: 10.1016/J.Mrfmmm.2016.03.003  0.48
2016 Yauk CL, Buick JK, Williams A, Swartz CD, Recio L, Li HH, Fornace AJ, Thomson EM, Aubrecht J. Application of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9. Environmental and Molecular Mutagenesis. PMID 26946220 DOI: 10.1002/Em.22004  0.48
2016 Datta K, Suman S, Kumar S, Fornace AJ. Colorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome Pathway. Journal of Cancer. 7: 174-83. PMID 26819641 DOI: 10.7150/Jca.13387  0.48
2016 Pannkuk EL, Laiakis EC, Mak TD, Astarita G, Authier S, Wong K, Fornace AJ. A lipidomic and metabolomic serum signature from nonhuman primates exposed to ionizing radiation Metabolomics. 12. DOI: 10.1007/s11306-016-1010-0  0.48
2015 Suman S, Kumar S, Moon BH, Strawn SJ, Thakor H, Fan Z, Shay JW, Fornace AJ, Datta K. Relative Biological Effectiveness of Energetic Heavy Ions for Intestinal Tumorigenesis Shows Male Preponderance and Radiation Type and Energy Dependence in APC(1638N/+) Mice. International Journal of Radiation Oncology, Biology, Physics. PMID 26725728 DOI: 10.1016/J.Ijrobp.2015.10.057  0.48
2015 Mak TD, Tyburski JB, Krausz KW, Kalinich JF, Gonzalez FJ, Fornace AJ. Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat. Metabolomics : Official Journal of the Metabolomic Society. 11: 1082-1094. PMID 26557048 DOI: 10.1007/S11306-014-0765-4  0.6
2015 Suman S, Kumar S, Fornace AJ, Datta K. Decreased RXRα is Associated with Increased β-Catenin/TCF4 in (56)Fe-Induced Intestinal Tumors. Frontiers in Oncology. 5: 218. PMID 26500891 DOI: 10.3389/Fonc.2015.00218  0.48
2015 Goudarzi M, Weber WM, Chung J, Doyle-Eisele M, Melo DR, Mak TD, Strawn SJ, Brenner DJ, Guilmette R, Fornace AJ. Serum Dyslipidemia Is Induced by Internal Exposure to Strontium-90 in Mice, Lipidomic Profiling Using a Data-Independent Liquid Chromatography-Mass Spectrometry Approach. Journal of Proteome Research. 14: 4039-49. PMID 26262552 DOI: 10.1021/Acs.Jproteome.5B00576  0.48
2015 Barcellos-Hoff MH, Blakely EA, Burma S, Fornace AJ, Gerson S, Hlatky L, Kirsch DG, Luderer U, Shay J, Wang Y, Weil MM. Concepts and challenges in cancer risk prediction for the space radiation environment. Life Sciences in Space Research. 6: 92-103. PMID 26256633 DOI: 10.1016/J.Lssr.2015.07.006  0.48
2015 Pannkuk EL, Laiakis EC, Authier S, Wong K, Fornace AJ. Global Metabolomic Identification of Long-Term Dose-Dependent Urinary Biomarkers in Nonhuman Primates Exposed to Ionizing Radiation. Radiation Research. 184: 121-33. PMID 26230079 DOI: 10.1667/Rr14091.1  0.48
2015 Li HH, Wang YW, Chen R, Zhou B, Ashwell JD, Fornace AJ. Ionizing Radiation Impairs T Cell Activation by Affecting Metabolic Reprogramming. International Journal of Biological Sciences. 11: 726-36. PMID 26078715 DOI: 10.7150/Ijbs.12009  0.48
2015 Goudarzi M, Weber WM, Mak TD, Chung J, Doyle-Eisele M, Melo DR, Strawn SJ, Brenner DJ, Guilmette RA, Fornace AJ. A Comprehensive Metabolomic Investigation in Urine of Mice Exposed to Strontium-90. Radiation Research. 183: 665-74. PMID 26010713 DOI: 10.1667/Rr14011.1  0.48
2015 LaConti JJ, Laiakis EC, Mays AD, Peran I, Kim SE, Shay JW, Riegel AT, Fornace AJ, Wellstein A. Distinct serum metabolomics profiles associated with malignant progression in the KrasG12D mouse model of pancreatic ductal adenocarcinoma. Bmc Genomics. 16: S1. PMID 25923219 DOI: 10.1186/1471-2164-16-S1-S1  0.48
2015 Zhang L, Kim S, Jia G, Buhmeida A, Dallol A, Wright WE, Fornace AJ, Al-Qahtani M, Shay JW. Exome Sequencing of Normal and Isogenic Transformed Human Colonic Epithelial Cells (HCECs) Reveals Novel Genes Potentially Involved in the Early Stages of Colorectal Tumorigenesis. Bmc Genomics. 16: S8. PMID 25923178 DOI: 10.1186/1471-2164-16-S1-S8  0.48
2015 Laiakis EC, Trani D, Moon BH, Strawn SJ, Fornace AJ. Metabolomic profiling of urine samples from mice exposed to protons reveals radiation quality and dose specific differences Radiation Research. 183: 382-390. PMID 25768838 DOI: 10.1667/Rr3967.1  0.48
2015 Bouhifd M, Andersen ME, Baghdikian C, Boekelheide K, Crofton KM, Fornace AJ, Kleensang A, Li H, Livi C, Maertens A, McMullen PD, Rosenberg M, Thomas R, Vantangoli M, Yager JD, et al. The human toxome project. Altex. 32: 112-24. PMID 25742299 DOI: 10.14573/Altex.1502091  0.48
2015 Li HH, Hyduke DR, Chen R, Heard P, Yauk CL, Aubrecht J, Fornace AJ. Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells. Environmental and Molecular Mutagenesis. 56: 505-19. PMID 25733355 DOI: 10.1002/Em.21941  0.48
2015 Buick JK, Moffat I, Williams A, Swartz CD, Recio L, Hyduke DR, Li HH, Fornace AJ, Aubrecht J, Yauk CL. Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells. Environmental and Molecular Mutagenesis. 56: 520-34. PMID 25733247 DOI: 10.1002/Em.21940  0.48
2015 Mak TD, Laiakis EC, Goudarzi M, Fornace AJ. Selective paired ion contrast analysis: a novel algorithm for analyzing postprocessed LC-MS metabolomics data possessing high experimental noise. Analytical Chemistry. 87: 3177-86. PMID 25683158 DOI: 10.1021/Ac504012A  0.6
2015 Moffat I, Chepelev NL, Labib S, Bourdon-Lacombe J, Kuo B, Buick JK, Lemieux F, Williams A, Halappanavar S, Malik AI, Luijten M, Aubrecht J, Hyduke DR, Fornace AJ, Swartz CD, et al. Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water. Critical Reviews in Toxicology. 45: 1-43. PMID 25605026 DOI: 10.3109/10408444.2014.973934  0.48
2015 Goudarzi M, Weber WM, Mak TD, Chung J, Doyle-Eisele M, Melo DR, Brenner DJ, Guilmette RA, Fornace AJ. Metabolomic and lipidomic analysis of serum from mice exposed to an internal emitter, cesium-137, using a shotgun LC-MS(E) approach. Journal of Proteome Research. 14: 374-84. PMID 25333951 DOI: 10.1021/Pr500913N  0.48
2015 Suman S, Kallakury BVS, Fornace AJ, Datta K. Protracted upregulation of leptin and IGF1 is associated with activation of PI3K/Akt and JAK2 pathway in mouse intestine after ionizing radiation exposure International Journal of Biological Sciences. 11: 274-283. DOI: 10.7150/ijbs.10684  0.48
2015 Mak TD, Laiakis EC, Goudarzi M, Fornace AJ. Selective Paired Ion Contrast Analysis: A Novel Algorithm for Analyzing Postprocessed LC-MS Metabolomics Data Possessing High Experimental Noise Analytical Chemistry. 87: 3177-3186. DOI: 10.1021/ac504012a  0.48
2015 Williams A, Buick JK, Moffat I, Swartz CD, Recio L, Hyduke DR, Li HH, Fornace AJ, Aubrecht J, Yauk CL. A predictive toxicogenomics signature to classify genotoxic versus non-genotoxic chemicals in human TK6 cells Data in Brief. 5: 77-83. DOI: 10.1016/j.dib.2015.08.013  0.48
2014 Datta K, Suman S, Fornace AJ. Radiation persistently promoted oxidative stress, activated mTOR via PI3K/Akt, and downregulated autophagy pathway in mouse intestine. The International Journal of Biochemistry & Cell Biology. 57: 167-76. PMID 25449263 DOI: 10.1016/J.Biocel.2014.10.022  0.48
2014 Laiakis EC, Strassburg K, Bogumil R, Lai S, Vreeken RJ, Hankemeier T, Langridge J, Plumb RS, Fornace AJ, Astarita G. Metabolic phenotyping reveals a lipid mediator response to ionizing radiation. Journal of Proteome Research. 13: 4143-54. PMID 25126707 DOI: 10.1021/Pr5005295  0.48
2014 Suman S, Moon BH, Thakor H, Fornace AJ, Datta K. Wip1 abrogation decreases intestinal tumor frequency in APCMin/+ mice irrespective of radiation quality Radiation Research. 182: 345-349. PMID 25117622 DOI: 10.1667/Rr13770.1  0.48
2014 Goudarzi M, Mak TD, Chen C, Smilenov LB, Brenner DJ, Fornace AJ. The effect of low dose rate on metabolomic response to radiation in mice. Radiation and Environmental Biophysics. 53: 645-57. PMID 25047638 DOI: 10.1007/S00411-014-0558-1  0.6
2014 Tong M, McHardy I, Ruegger P, Goudarzi M, Kashyap PC, Haritunians T, Li X, Graeber TG, Schwager E, Huttenhower C, Fornace AJ, Sonnenburg JL, McGovern DP, Borneman J, Braun J. Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism. The Isme Journal. 8: 2193-206. PMID 24781901 DOI: 10.1038/Ismej.2014.64  0.48
2014 Li HH, Tyburski JB, Wang YW, Strawn S, Moon BH, Kallakury BV, Gonzalez FJ, Fornace AJ. Modulation of fatty acid and bile acid metabolism by peroxisome proliferator-activated receptor α protects against alcoholic liver disease. Alcoholism, Clinical and Experimental Research. 38: 1520-31. PMID 24773203 DOI: 10.1111/Acer.12424  0.48
2014 Laiakis EC, Mak TD, Anizan S, Amundson SA, Barker CA, Wolden SL, Brenner DJ, Fornace AJ. Development of a metabolomic radiation signature in urine from patients undergoing total body irradiation. Radiation Research. 181: 350-61. PMID 24673254 DOI: 10.1667/Rr13567.1  0.48
2014 Trani D, Nelson SA, Moon BH, Swedlow JJ, Williams EM, Strawn SJ, Appleton PL, Kallakury B, Näthke I, Fornace AJ. High-energy particle-induced tumorigenesis throughout the gastrointestinal tract. Radiation Research. 181: 162-71. PMID 24512616 DOI: 10.1667/Rr13502.1  0.48
2014 Cheema AK, Suman S, Kaur P, Singh R, Fornace AJ, Datta K. Long-term differential changes in mouse intestinal metabolomics after γ and heavy ion radiation exposure. Plos One. 9: e87079. PMID 24475228 DOI: 10.1371/Journal.Pone.0087079  0.48
2014 Kafle A, Coy SL, Wong BM, Fornace AJ, Glick JJ, Vouros P. Understanding gas phase modifier interactions in rapid analysis by differential mobility-tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 25: 1098-113. PMID 24452298 DOI: 10.1007/S13361-013-0808-5  0.48
2014 Goudarzi M, Weber W, Mak TD, Chung J, Doyle-Eisele M, Melo D, Brenner DJ, Guilmette RA, Fornace AJ. Development of urinary biomarkers for internal exposure by cesium-137 using a metabolomics approach in mice Radiation Research. 181: 54-64. PMID 24377719 DOI: 10.1667/Rr13479.1  0.48
2014 Mak TD, Laiakis EC, Goudarzi M, Fornace AJ. MetaboLyzer: A novel statistical workflow for analyzing postprocessed LC-MS metabolomics data Analytical Chemistry. 86: 506-513. PMID 24266674 DOI: 10.1021/Ac402477Z  0.48
2014 Kleensang A, Maertens A, Rosenberg M, Fitzpatrick S, Lamb J, Auerbach S, Brennan R, Crofton KM, Gordon B, Fornace AJ, Gaido K, Gerhold D, Haw R, Henney A, Ma'ayan A, et al. t4 workshop report: Pathways of Toxicity. Altex. 31: 53-61. PMID 24127042 DOI: 10.14573/Altex.1309261  0.48
2014 Lee JS, Park JR, Kwon OS, Kim H, Fornace AJ, Cha HJ. Off-target response of a Wip1 chemical inhibitor in skin keratinocytes. Journal of Dermatological Science. 73: 125-34. PMID 24126074 DOI: 10.1016/J.Jdermsci.2013.09.003  0.48
2014 Moon B, Suman S, Li H, Yang Q, Strawn SJ, LoBello J, Mazur SJ, Appella E, Chen S, Fornace AJ. Abstract 1998: Deficient expression of oncogenic Wip1 (PPM1D) negatively regulates melanoma progression and metastasis Cancer Research. 74: 1998-1998. DOI: 10.1158/1538-7445.Am2014-1998  0.4
2014 Mak TD, Tyburski JB, Krausz KW, Kalinich JF, Gonzalez FJ, Fornace AJ. Exposure to ionizing radiation reveals global dose- and time-dependent changes in the urinary metabolome of rat Metabolomics. DOI: 10.1007/s11306-014-0765-4  0.48
2014 Goudarzi M, Mak TD, Chen C, Smilenov LB, Brenner DJ, Fornace AJ. The effect of low dose rate on metabolomic response to radiation in mice Radiation and Environmental Biophysics. 53: 645-657. DOI: 10.1007/s00411-014-0558-1  0.48
2013 McHardy IH, Goudarzi M, Tong M, Ruegger PM, Schwager E, Weger JR, Graeber TG, Sonnenburg JL, Horvath S, Huttenhower C, McGovern DP, Fornace AJ, Borneman J, Braun J. Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships. Microbiome. 1: 17. PMID 24450808 DOI: 10.1186/2049-2618-1-17  0.48
2013 Li HH, Doiron K, Patterson AD, Gonzalez FJ, Fornace AJ. Identification of serum insulin-like growth factor binding protein 1 as diagnostic biomarker for early-stage alcohol-induced liver disease. Journal of Translational Medicine. 11: 266. PMID 24152801 DOI: 10.1186/1479-5876-11-266  0.48
2013 Salvador JM, Brown-Clay JD, Fornace AJ. Gadd45 in stress signaling, cell cycle control, and apoptosis Advances in Experimental Medicine and Biology. 793: 1-19. PMID 24104470 DOI: 10.1007/978-1-4614-8289-5_1  0.48
2013 Suman S, Datta K, Chakraborty K, Kulkarni SS, Doiron K, Fornace AJ, Sree Kumar K, Hauer-Jensen M, Ghosh SP. Gamma tocotrienol, a potent radioprotector, preferentially upregulates expression of anti-apoptotic genes to promote intestinal cell survival Food and Chemical Toxicology. 60: 488-496. PMID 23941772 DOI: 10.1016/J.Fct.2013.08.011  0.48
2013 Suman S, Rodriguez OC, Winters TA, Fornace AJ, Albanese C, Datta K. Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production. Aging. 5: 607-22. PMID 23928451  0.48
2013 Goudarzi M, Koga T, Khozoie C, Mac TD, Kang BH, Fornace AJ, Peters JM. PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity Toxicology. 311: 87-98. PMID 23851158 DOI: 10.1016/J.Tox.2013.07.002  0.48
2013 Hyduke DR, Laiakis EC, Li HH, Fornace AJ. Identifying radiation exposure biomarkers from mouse blood transcriptome International Journal of Bioinformatics Research and Applications. 9: 365-385. PMID 23797995 DOI: 10.1504/Ijbra.2013.054701  0.48
2013 Datta K, Suman S, Kallakury BVS, Fornace AJ. Heavy Ion Radiation Exposure Triggered Higher Intestinal Tumor Frequency and Greater β-Catenin Activation than γ Radiation in APCMin/+ Mice Plos One. 8. PMID 23555653 DOI: 10.1371/Journal.Pone.0059295  0.48
2013 Trani D, Moon BH, Kallakury B, Hartmann DP, Datta K, Fornace AJ. Sex-dependent differences in intestinal tumorigenesis induced in Apc1638N/+ mice by exposure to γ rays International Journal of Radiation Oncology Biology Physics. 85: 223-229. PMID 22503525 DOI: 10.1016/J.Ijrobp.2012.02.053  0.48
2013 Laiakis EC, Mak TD, Anizan S, Amundson SA, Barker CA, Wolden SL, Brenner DJ, Fornace AJ. Abstract 423: Metabolomic analysis of urine from patients undergoing total body irradiation. Cancer Research. 73: 423-423. DOI: 10.1158/1538-7445.Am2013-423  0.6
2013 Coy SL, Krylov EV, Nazarov EG, Fornace AJ, Kidd RD. Differential mobility spectrometry with nanospray ion source as a compact detector for small organics and inorganics International Journal For Ion Mobility Spectrometry. 16: 217-227. DOI: 10.1007/s12127-013-0135-3  0.48
2012 Datta K, Hyduke DR, Suman S, Moon BH, Johnson MD, Fornace AJ. Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland. Radiation Oncology (London, England). 7: 205. PMID 23216862 DOI: 10.1186/1748-717X-7-205  0.48
2012 Datta K, Suman S, Kallakury BVS, Fornace AJ. Exposure to heavy ion radiation induces persistent oxidative stress in mouse intestine Plos One. 7. PMID 22936983 DOI: 10.1371/Journal.Pone.0042224  0.48
2012 Suman S, Datta K, Doiron K, Ren C, Kumar R, Taft DR, Fornace AJ, Maniar M. Radioprotective effects of on upon oral administration Journal of Radiation Research. 53: 368-376. PMID 22739006 DOI: 10.1269/Jrr.11191  0.48
2012 Suman S, Datta K, Trani D, Laiakis EC, Strawn SJ, Fornace AJ. Relative biological effectiveness of 12C and 28Si radiation in C57BL/6J mice Radiation and Environmental Biophysics. 51: 303-309. PMID 22562428 DOI: 10.1007/S00411-012-0418-9  0.48
2012 Suman S, Johnson MD, Fornace AJ, Datta K. Exposure to ionizing radiation causes long-term increase in serum estradiol and activation of PI3K-Akt signaling pathway in mouse mammary gland. International Journal of Radiation Oncology, Biology, Physics. 84: 500-7. PMID 22381906 DOI: 10.1016/J.Ijrobp.2011.12.033  0.48
2012 Suman S, Maniar M, Fornace AJ, Datta K. Administration of ON 01210.Na after exposure to ionizing radiation protects bone marrow cells by attenuating DNA damage response Radiation Oncology. 7. PMID 22264334 DOI: 10.1186/1748-717X-7-6  0.48
2012 Lowe J, Cha H, Lee MO, Mazur SJ, Appella E, Fornace AJ. Regulation of the Wip1 phosphatase and its effects on the stress response. Frontiers in Bioscience (Landmark Edition). 17: 1480-98. PMID 22201816 DOI: 10.2741/3999  0.48
2012 Laiakis EC, Hyduke DR, Fornace AJ. Comparison of mouse urinary metabolic profiles after exposure to the inflammatory stressors γ radiation and lipopolysaccharide Radiation Research. 177: 187-199. PMID 22128784 DOI: 10.1667/Rr2771.1  0.48
2012 Datta K, Suman S, Trani D, Doiron K, Rotolo JA, Kallakury BV, Kolesnick R, Cole MF, Fornace AJ. Accelerated hematopoietic toxicity by high energy (56)Fe radiation. International Journal of Radiation Biology. 88: 213-22. PMID 22077279 DOI: 10.3109/09553002.2012.639434  0.48
2012 Lee JS, Lee HJ, Moon BH, Song SH, Lee MO, Shim SH, Kim HS, Lee MC, Kwon JT, Fornace AJ, Kim SU, Cha HJ. Generation of cancerous neural stem cells forming glial tumor by oncogenic stimulation. Stem Cell Reviews. 8: 532-45. PMID 21755312 DOI: 10.1007/S12015-011-9280-4  0.48
2011 Manna SK, Patterson AD, Yang Q, Krausz KW, Idle JR, Fornace AJ, Gonzalez FJ. UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model Journal of Proteome Research. 10: 4120-4133. PMID 21749142 DOI: 10.1021/Pr200310S  0.48
2011 Coy SL, Cheema AK, Tyburski JB, Laiakis EC, Collins SP, Fornace A. Radiation metabolomics and its potential in biodosimetry. International Journal of Radiation Biology. 87: 802-23. PMID 21692691 DOI: 10.3109/09553002.2011.556177  0.48
2011 Lee MO, Lee HJ, Kim MA, Kim EK, Lee JH, Heo JH, Lee SH, Cho SH, Fornace AJ, Jeong HC, Cha HJ. P16Ink4a suppression of lung adenocarcinoma by Bmi-1 in the presence of p38 activation Journal of Thoracic Oncology. 6: 423-431. PMID 21164364 DOI: 10.1097/Jto.0B013E3182018Ace  0.48
2011 Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A, Honma M, et al. New and emerging technologies for genetic toxicity testing. Environmental and Molecular Mutagenesis. 52: 205-23. PMID 20740635 DOI: 10.1002/Em.20614  0.48
2011 Fornace AJ. Correction: Gadd45a functions as a promoter or suppressor of breast cancer dependent on the oncogenic stress (Cancer Research (2010) 70, (9671-9681)) Cancer Research. 71: 1506. DOI: 10.1158/0008-5472.CAN-10-4479  0.48
2011 Sheikh KD, Khanna S, Byers SW, Fornace A, Cheema AK. Small molecule metabolite extraction strategy for improving LC/MS detection of cancer cell metabolome Journal of Biomolecular Techniques. 22: 1-4.  0.48
2010 Romanov VS, Abramova MV, Svetlikova SB, Bykova TV, Zubova SG, Aksenov ND, Fornace AJ, Pospelova TV, Pospelov VA. p21Waf1 is required for cellular senescence but not for cell cycle arrest induced by the HDAC inhibitor sodium butyrate Cell Cycle. 9: 3945-3955. PMID 20935470 DOI: 10.4161/Cc.9.19.13160  0.48
2010 Laiakis EC, Morris GA, Fornace AJ, Howie SR. Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot study. Plos One. 5. PMID 20844590 DOI: 10.1371/Journal.Pone.0012655  0.48
2010 Kim JJ, Lee JS, Moon BH, Lee MO, Song SH, Li H, Fornace AJ, Cha HJ. Wip1-expressing feeder cells retain pluripotency of co-cultured mouse embryonic stem cells under leukemia inhibitory factor-deprivated condition Archives of Pharmacal Research. 33: 1253-1260. PMID 20803129 DOI: 10.1007/S12272-010-0816-Y  0.48
2010 Cha Y, Moon BH, Lee MO, Ahn HJ, Lee HJ, Lee KA, Fornace AJ, Kim KS, Cha HJ, Park KS. Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling Stem Cells. 28: 1476-1486. PMID 20641039 DOI: 10.1002/Stem.470  0.48
2010 Manna SK, Patterson AD, Yang Q, Krausz KW, Li H, Idle JR, Fornace AJ, Gonzalez FJ. Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the ppara -null mouse Journal of Proteome Research. 9: 4176-4188. PMID 20540569 DOI: 10.1021/Pr100452B  0.48
2010 Goodsaid FM, Amur S, Aubrecht J, Burczynski ME, Carl K, Catalano J, Charlab R, Close S, Cornu-Artis C, Essioux L, Fornace AJ, Hinman L, Hong H, Hunt I, Jacobson-Kram D, et al. Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact. Nature Reviews. Drug Discovery. 9: 435-45. PMID 20514070 DOI: 10.1038/Nrd3116  0.48
2010 Cha H, Lowe JM, Li H, Lee JS, Belova GI, Bulavin DV, Fornace AJ. Wip1 directly dephosphorylates γ-H2AX and attenuates the DNA damage response Cancer Research. 70: 4112-4122. PMID 20460517 DOI: 10.1158/0008-5472.Can-09-4244  0.48
2010 Coy SL, Krylov EV, Schneider BB, Covey TR, Brenner DJ, Tyburski JB, Patterson AD, Krausz KW, Fornace AJ, Nazarov EG. Detection of Radiation-Exposure Biomarkers by Differential Mobility Prefiltered Mass Spectrometry (DMS-MS). International Journal of Mass Spectrometry. 291: 108-117. PMID 20305793 DOI: 10.1016/J.Ijms.2010.01.013  0.4
2010 Lowe JM, Cha H, Yang Q, Fornace AJ. Nuclear factor-κB (NF-κB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase Journal of Biological Chemistry. 285: 5249-5257. PMID 20007970 DOI: 10.1074/Jbc.M109.034579  0.48
2010 Mak T, Tyburski JB, Kalinich JF, Fornace AJ. Abstract 116: A novel methodology for analyzing post-processed LC/MS metabolomics data Cancer Research. 70: 116-116. DOI: 10.1158/1538-7445.Am10-116  0.4
2010 Coy SL, Krylov EV, Schneider BB, Covey TR, Brenner DJ, Tyburski JB, Patterson AD, Krausz KW, Fornace AJ, Nazarov EG. Detection of radiation-exposure biomarkers by differential mobility prefiltered mass spectrometry (DMS-MS) International Journal of Mass Spectrometry. 291: 108-117. DOI: 10.1016/j.ijms.2010.01.013  0.48
2010 Hyduke DR, Amundson SA, Fornace AJ. Complexity of stress signaling Handbook of Cell Signaling, 2/E. 3: 2107-2125. DOI: 10.1016/B978-0-12-374145-5.00257-6  0.48
2010 Trani D, Datta K, Doiron K, Kallakury B, Fornace AJ. Enhanced intestinal tumor multiplicity and grade in vivo after HZE exposure: Mouse models for space radiation risk estimates Radiation and Environmental Biophysics. 49: 389-396. DOI: 10.1007/s00411-010-0292-2  0.48
2009 Tyburski JB, Patterson AD, Krausz KW, Slavk J, Fornace AJ, Gonzalez FJ, Idle JR. Radiation metabolomics. 2. dose- and time-dependent urinary excretion of deaminated purines and pyrimidines after sublethal gamma-radiation exposure in mice Radiation Research. 172: 42-57. PMID 19580506 DOI: 10.1667/Rr1703.1  0.48
2009 Lee JS, Lee MO, Moon BH, Shim SH, Fornace AJ, Cha HJ. Senescent growth arrest in mesenchymal stem cells is bypassed by Wip1-mediated downregulation of intrinsic stress signaling pathways Stem Cells. 27: 1963-1975. PMID 19544416 DOI: 10.1002/Stem.121  0.48
2009 Ellinger-Ziegelbauer H, Fostel JM, Aruga C, Bauer D, Boitier E, Deng S, Dickinson D, Le Fevre AC, Fornace AJ, Grenet O, Gu Y, Hoflack JC, Shiiyama M, Smith R, Snyder RD, et al. Characterization and interlaboratory comparison of a gene expression signature for differentiating genotoxic mechanisms. Toxicological Sciences : An Official Journal of the Society of Toxicology. 110: 341-52. PMID 19465456 DOI: 10.1093/Toxsci/Kfp103  0.48
2009 Park HU, Suy S, Danner M, Dailey V, Zhang Y, Li H, Hyduke DR, Collins BT, Gagnon G, Kallakury B, Kumar D, Brown ML, Fornace A, Dritschilo A, Collins SP. AMP-activated protein kinase promotes human prostate cancer cell growth and survival. Molecular Cancer Therapeutics. 8: 733-41. PMID 19372545 DOI: 10.1158/1535-7163.Mct-08-0631  0.48
2009 Demidov ON, Cha H, Bulavin DV, Fornace AJ. Wip1, an oncogene targeting tumor suppressors expressed in intestinal stem cells Current Colorectal Cancer Reports. 5: 197-202. DOI: 10.1007/S11888-009-0027-4  0.48
2008 Tyburski JB, Patterson AD, Krausz KW, Slavík J, Fornace AJ, Gonzalez FJ, Idle JR. Radiation metabolomics. 1. Identification of minimally invasive urine biomarkers for gamma-radiation exposure in mice Radiation Research. 170: 1-14. PMID 18582157 DOI: 10.1667/Rr1265.1  0.48
2008 Lu X, Yang C, Hill R, Yin C, Hollander MC, Fornace AJ, Van Dyke T. Inactivation of gadd45a sensitizes epithelial cancer cells to ionizing radiation in vivo resulting in prolonged survival Cancer Research. 68: 3579-3583. PMID 18483238 DOI: 10.1158/0008-5472.Can-07-5533  0.48
2008 Amundson SA, Do KT, Vinikoor LC, Lee RA, Koch-Paiz CA, Ahn J, Reimers M, Chen Y, Scudiero DA, Weinstein JN, Trent JM, Bittner ML, Meltzer PS, Fornace AJ. Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen. Cancer Research. 68: 415-24. PMID 18199535 DOI: 10.1158/0008-5472.Can-07-2120  0.48
2008 Patterson AD, Li H, Eichler GS, Krausz KW, Weinstein JN, Fornace AJ, Gonzalez FJ, Idle JR. UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation Analytical Chemistry. 80: 665-674. PMID 18173289 DOI: 10.1021/Ac701807V  0.48
2008 Amundson SA, Do KT, Vinikoor LC, Lee RA, Koch-Paiz CA, Ahn J, Reimers M, Chen Y, Scudiero DA, Weinstein JN, Trent JM, Bittner ML, Meltzer PS, Fornace AJ. Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen (Cancer Research (January 15, 2008) 68 (415-424)) Cancer Research. 68: 1245. DOI: 10.1158/0008-5472.Can-68-4-Cor4  0.48
2008 Hyduke DR, Li HH, Park HU, Collins SP, Suy S, Aubrecht J, Fornace AJ. A network based approach for the identification of stress responses in lead compound transcriptome profiles Aiche Annual Meeting, Conference Proceedings 0.48
2007 Ku WW, Aubrecht J, Mauthe RJ, Schiestl RH, Fornace AJ. Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 20-5. PMID 17548889 DOI: 10.1093/Toxsci/Kfm147  0.48
2007 Cha H, Wang X, Li H, Fornace AJ. A functional role for p38 MAPK in modulating mitotic transit in the absence of stress Journal of Biological Chemistry. 282: 22984-22992. PMID 17548358 DOI: 10.1074/Jbc.M700735200  0.48
2007 Li HH, Aubrecht J, Fornace AJ. Toxicogenomics: Overview and potential applications for the study of non-covalent DNA interacting chemicals Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 623: 98-108. PMID 17548094 DOI: 10.1016/J.Mrfmmm.2007.03.013  0.48
2007 Jirmanova L, Janković D, Fornace AJ, Ashwell JD. Gadd45α regulates p38-dependent dendritic cell cytokine production and Th1 differentiation Journal of Immunology. 178: 4153-4158. PMID 17371971 DOI: 10.4049/Jimmunol.178.7.4153  0.48
2007 Demidov ON, Kek C, Shreeram S, Timofeev O, Fornace AJ, Appella E, Bulavin DV. The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis Oncogene. 26: 2502-2506. PMID 17016428 DOI: 10.1038/Sj.Onc.1210032  0.48
2006 Shreeram S, Weng KH, Demidov ON, Kek C, Yamaguchi H, Fornace AJ, Anderson CW, Appella E, Bulavin DV. Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase Journal of Experimental Medicine. 203: 2793-2799. PMID 17158963 DOI: 10.1084/Jem.20061563  0.48
2006 Liebe B, Petukhova G, Barchi M, Bellani M, Braselmann H, Nakano T, Pandita TK, Jasin M, Fornace A, Meistrich ML, Baarends WM, Schimenti J, de Lange T, Keeney S, Camerini-Otero RD, et al. Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages. Experimental Cell Research. 312: 3768-81. PMID 17010969 DOI: 10.1016/J.Yexcr.2006.07.019  0.48
2006 Shreeram S, Demidov ON, Hee WK, Yamaguchi H, Onishi N, Kek C, Timofeev ON, Dudgeon C, Fornace AJ, Anderson CW, Minami Y, Appella E, Bulavin DV. Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways Molecular Cell. 23: 757-764. PMID 16949371 DOI: 10.1016/J.Molcel.2006.07.010  0.48
2006 Abramova MV, Pospelova TV, Nikulenkov FP, Hollander CM, Fornace AJ, Pospelov VA. G1/S arrest induced by histone deacetylase inhibitor sodium butyrate in E1A + Ras-transformed cells is mediated through down-regulation of E2F activity and stabilization of β-catenin Journal of Biological Chemistry. 281: 21040-21051. PMID 16717102 DOI: 10.1074/Jbc.M511059200  0.48
2006 Cai Q, Dmitrieva NI, Ferraris JD, Michea LF, Salvador JM, Hollander MC, Fornace AJ, Fenton RA, Burg MB. Effects of expression of p53 and Gadd45 on osmotic tolerance of renal inner medullary cells American Journal of Physiology - Renal Physiology. 291: F341-F349. PMID 16597604 DOI: 10.1152/Ajprenal.00518.2005  0.48
2006 Dudgeon C, Kek C, Demidov ON, Saito SI, Fernandes K, Diot A, Bourdon JC, Lane DP, Appella E, Fornace AJ, Bulavin DV. Tumor susceptibility and apoptosis defect in a mouse strain expressing a human p53 transgene Cancer Research. 66: 2928-2936. PMID 16540640 DOI: 10.1158/0008-5472.Can-05-2063  0.48
2006 Patterson AD, Hollander MC, Miller GF, Fornace AJ. Gadd34 requirement for normal hemoglobin synthesis. Molecular and Cellular Biology. 26: 1644-53. PMID 16478986 DOI: 10.1128/Mcb.26.5.1644-1653.2006  0.48
2006 Patterson AD, Hildesheim J, Fornace AJ, Hollander MC. Neural tube development requires the cooperation of p53- and Gadd45a-associated pathways Birth Defects Research Part a - Clinical and Molecular Teratology. 76: 129-132. PMID 16470852 DOI: 10.1002/Bdra.20217  0.48
2006 Bishop AJ, Kosaras B, Hollander MC, Fornace A, Sidman RL, Schiestl RH. p21 controls patterning but not homologous recombination in RPE development. Dna Repair. 5: 111-20. PMID 16202662 DOI: 10.1016/J.Dnarep.2005.08.015  0.48
2005 Belova GI, Demidov ON, Fornace AJ, Bulavin DV. Chemical inhibition of Wip1 phosphatase contributes to suppression of tumorigenesis Cancer Biology and Therapy. 4: 1154-1158. PMID 16258255 DOI: 10.4161/Cbt.4.10.2204  0.48
2005 Gupta M, Gupta SK, Balliet AG, Hollander MC, Fornace AJ, Hoffman B, Liebermann DA. Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis Oncogene. 24: 7170-7179. PMID 16170381 DOI: 10.1038/Sj.Onc.1208847  0.48
2005 Hollander MC, Philburn RT, Patterson AD, Velasco-Miguel S, Friedberg EC, Linnoila RI, Fornace AJ. Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis Proceedings of the National Academy of Sciences of the United States of America. 102: 13200-13205. PMID 16141330 DOI: 10.1073/Pnas.0503133102  0.48
2005 Jirmanova L, Bulavin DV, Fornace AJ. Inhibition of the ATR/Chk1 pathway induces a p38-dependent S-phase delay in mouse embryonic stem cells Cell Cycle. 4: 1428-1434. PMID 16138010 DOI: 10.4161/Cc.4.10.2055  0.48
2005 Mittelstadt PR, Salvador JM, Fornace AJ, Ashwell JD. Activating p38 MAPK: New tricks for an old kinase Cell Cycle. 4: 1189-1192. PMID 16103752 DOI: 10.4161/Cc.4.9.2043  0.48
2005 Khaled AR, Bulavin DV, Kittipatarin C, Li WQ, Alvarez M, Kim K, Young HA, Fornace AJ, Durum SK. Cytokine-driven cell cycling is mediated through Cdc25A Journal of Cell Biology. 169: 755-763. PMID 15928203 DOI: 10.1083/Jcb.200409099  0.48
2005 Hollander MC, Philburn RT, Patterson AD, Wyatt MA, Fornace AJ. Genomic instability in Gadd45a-/- cells is coupled with S-phase checkpoint defects Cell Cycle. 4: 704-709. PMID 15846075 DOI: 10.4161/Cc.4.5.1675  0.48
2005 Amundson SA, Do KT, Vinikoor L, Koch-Paiz CA, Bittner ML, Trent JM, Meltzer P, Fornace AJ. Stress-specific signatures: Expression profiling of p53 wild-type and -null human cells Oncogene. 24: 4572-4579. PMID 15824734 DOI: 10.1038/Sj.Onc.1208653  0.48
2005 Hollander MC, Patterson AD, Salvador JM, Anver MR, Hunger SP, Fornace AJ. Gadd45a acts as a modifier locus for lymphoblastic lymphoma Leukemia. 19: 847-850. PMID 15744335 DOI: 10.1038/Sj.Leu.2403711  0.48
2005 Salvador JM, Mittelstadt PR, Belova GI, Fornace AJ, Ashwell JD. The autoimmune suppressor Gadd45α inhibits the T cell alternative p38 activation pathway Nature Immunology. 6: 396-402. PMID 15735649 DOI: 10.1038/Ni1176  0.48
2005 Salvador JM, Mittelstadt PR, Guszczynski T, Copeland TD, Yamaguchi H, Appella E, Fornace AJ, Ashwell JD. Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases Nature Immunology. 6: 390-395. PMID 15735648 DOI: 10.1038/Ni1177  0.48
2005 Roper JM, Gehen SC, Staversky RJ, Hollander MC, Fornace AJ, O'Reilly MA. Loss of Gadd45a does not modify the pulmonary response to oxidative stress American Journal of Physiology - Lung Cellular and Molecular Physiology. 288: L663-L671. PMID 15653712 DOI: 10.1152/Ajplung.00355.2004  0.48
2005 Hildesheim J, Salvador JM, Hollander MC, Fornace AJ. Casein kinase 2- and protein kinase A-regulated adenomatous polyposis coli and β-catenin cellular localization is dependent on p38 MAPK Journal of Biological Chemistry. 280: 17221-17226. PMID 15649893 DOI: 10.1074/Jbc.M410440200  0.48
2005 Denko NC, Fornace AJ. Editorial comment: Mutation Research Special Issue on stress responses Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 569: 1-2. PMID 15603748 DOI: 10.1016/J.Mrfmmm.2004.09.005  0.48
2005 Pal R, Datta A, Fornace AJ, Bittner ML, Dougherty ER. Boolean relationships among genes responsive to ionizing radiation in the NCI 60 ACDS Bioinformatics. 21: 1542-1549. PMID 15598836 DOI: 10.1093/Bioinformatics/Bti214  0.48
2004 Bulavin DV, Fornace AJ. p38 MAP kinase's emerging role as a tumor suppressor Advances in Cancer Research. 92: 95-118. PMID 15530558 DOI: 10.1016/S0065-230X(04)92005-2  0.48
2004 Amundson SA, Grace MB, McLeland CB, Epperly MW, Yeager A, Zhan Q, Greenberger JS, Fornace AJ. Human in vivo radiation-induced biomarkers: Gene expression changes in radiotherapy patients Cancer Research. 64: 6368-6371. PMID 15374940 DOI: 10.1158/0008-5472.Can-04-1883  0.48
2004 Hildesheim J, Fornace AJ. The dark side of light: the damaging effects of UV rays and the protective efforts of MAP kinase signaling in the epidermis. Dna Repair. 3: 567-80. PMID 15135725 DOI: 10.1016/J.Dnarep.2004.02.012  0.48
2004 Wang X, Wang RH, Li W, Xu X, Hollander MC, Fornace AJ, Deng CX. Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure. The Journal of Biological Chemistry. 279: 29606-14. PMID 15123655 DOI: 10.1074/Jbc.M312279200  0.48
2004 Koch-Paiz CA, Amundson SA, Bittner ML, Meltzer PS, Fornace AJ. Functional genomics of UV radiation responses in human cells. Mutation Research. 549: 65-78. PMID 15120963 DOI: 10.1016/J.Mrfmmm.2004.01.010  0.48
2004 Hildesheim J, Awwad RT, Fornace AJ. p38 Mitogen-activated protein kinase inhibitor protects the epidermis against the acute damaging effects of ultraviolet irradiation by blocking apoptosis and inflammatory responses. The Journal of Investigative Dermatology. 122: 497-502. PMID 15009736 DOI: 10.1111/J.1523-1747.2004.22229.X  0.48
2004 Bulavin DV, Phillips C, Nannenga B, Timofeev O, Donehower LA, Anderson CW, Appella E, Fornace AJ. Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway. Nature Genetics. 36: 343-50. PMID 14991053 DOI: 10.1038/Ng1317  0.48
2004 Amundson SA, Fornace AJ. Microarray approaches for analysis of cell cycle regulatory genes. Methods in Molecular Biology (Clifton, N.J.). 241: 125-41. PMID 14970650 DOI: 10.1385/1-59259-646-0:125  0.48
2004 Rockett JC, Burczynski ME, Fornace AJ, Herrmann PC, Krawetz SA, Dix DJ. Surrogate tissue analysis: monitoring toxicant exposure and health status of inaccessible tissues through the analysis of accessible tissues and cells. Toxicology and Applied Pharmacology. 194: 189-99. PMID 14736499 DOI: 10.1016/J.Taap.2003.09.005  0.48
2004 Hildesheim J, Belova GI, Tyner SD, Zhou X, Vardanian L, Fornace AJ. Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation. Oncogene. 23: 1829-37. PMID 14647429 DOI: 10.1038/Sj.Onc.1207301  0.48
2003 Jiang F, Li P, Fornace AJ, Nicosia SV, Bai W. G2/M arrest by 1,25-dihydroxyvitamin D3 in ovarian cancer cells mediated through the induction of GADD45 via an exonic enhancer. The Journal of Biological Chemistry. 278: 48030-40. PMID 14506229 DOI: 10.1074/Jbc.M308430200  0.48
2003 Bishop AJ, Hollander MC, Kosaras B, Sidman RL, Fornace AJ, Schiestl RH. Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Research. 63: 5335-43. PMID 14500365  0.48
2003 Goloudina A, Yamaguchi H, Chervyakova DB, Appella E, Fornace AJ, Bulavin DV. Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint. Cell Cycle (Georgetown, Tex.). 2: 473-8. PMID 12963847 DOI: 10.4161/Cc.2.5.482  0.48
2003 Amundson SA, Bittner M, Fornace AJ. Functional genomics as a window on radiation stress signaling. Oncogene. 22: 5828-33. PMID 12947389 DOI: 10.1038/Sj.Onc.1206681  0.48
2003 Yoo J, Ghiassi M, Jirmanova L, Balliet AG, Hoffman B, Fornace AJ, Liebermann DA, Bottinger EP, Roberts AB. Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation. The Journal of Biological Chemistry. 278: 43001-7. PMID 12933797 DOI: 10.1074/Jbc.M307869200  0.48
2003 Balliet AG, Hollander MC, Fornace AJ, Hoffman B, Liebermann DA. Comparative analysis of the genetic structure and chromosomal mapping of the murine Gadd45g/CR6 gene. Dna and Cell Biology. 22: 457-68. PMID 12932304 DOI: 10.1089/104454903322247334  0.48
2003 Saito S, Yamaguchi H, Higashimoto Y, Chao C, Xu Y, Fornace AJ, Appella E, Anderson CW. Phosphorylation site interdependence of human p53 post-translational modifications in response to stress. The Journal of Biological Chemistry. 278: 37536-44. PMID 12860987 DOI: 10.1074/Jbc.M305135200  0.48
2003 Amundson SA, Fornace AJ. Monitoring human radiation exposure by gene expression profiling: Possibilities and pitfalls Health Physics. 85: 36-42. PMID 12852469 DOI: 10.1097/00004032-200307000-00009  0.48
2003 Hollander MC, Poola-Kella S, Fornace AJ. Gadd34 functional domains involved in growth suppression and apoptosis Oncogene. 22: 3827-3832. PMID 12813455 DOI: 10.1038/Sj.Onc.1206567  0.48
2003 Bulavin DV, Demidenko ZN, Phillips C, Moody SA, Fornace AJ. Phosphorylation of Xenopus Cdc25C at Ser285 interferes with ability to activate a DNA damage replication checkpoint in pre-midblastula embryos. Cell Cycle (Georgetown, Tex.). 2: 263-6. PMID 12775939 DOI: 10.4161/Cc.2.3.396  0.48
2003 Bulavin DV, Higashimoto Y, Demidenko ZN, Meek S, Graves P, Phillips C, Zhao H, Moody SA, Appella E, Piwnica-Worms H, Fornace AJ. Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nature Cell Biology. 5: 545-51. PMID 12766774 DOI: 10.1038/Ncb994  0.48
2003 Bulavin DV, Kovalsky O, Hollander MC, Fornace AJ. Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a Molecular and Cellular Biology. 23: 3859-3871. PMID 12748288 DOI: 10.1128/Mcb.23.11.3859-3871.2003  0.48
2003 Amundson SA, Lee RA, Koch-Paiz CA, Bittner ML, Meltzer P, Trent JM, Fornace AJ. Differential responses of stress genes to low dose-rate γ irradiation Molecular Cancer Research. 1: 445-452. PMID 12692264  0.48
2003 Amundson SA, Fornace AJ. Complexity of Stress Signaling and Responses Handbook of Cell Signaling. 3: 179-184. DOI: 10.1016/B978-012124546-7/50660-4  0.48
2002 Hildesheim J, Bulavin DV, Anver MR, Alvord WG, Hollander MC, Vardanian L, Fornace AJ. Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53 Cancer Research. 62: 7305-7315. PMID 12499274  0.48
2002 Fan F, Jin S, Amundson SA, Tong T, Fan W, Zhao H, Zhu X, Mazzacurati L, Li X, Petrik KL, Fornace AJ, Rajasekaran B, Zhan Q. ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth. Oncogene. 21: 7488-96. PMID 12386811 DOI: 10.1038/Sj.Onc.1205896  0.48
2002 Morinobu A, Gadina M, Strober W, Visconti R, Fornace A, Montagna C, Feldman GM, Nishikomori R, O'Shea JJ. STAT4 serine phosphorylation is critical for IL-12-induced IFN-γ production but not for cell proliferation Proceedings of the National Academy of Sciences of the United States of America. 99: 12281-12286. PMID 12213961 DOI: 10.1073/Pnas.182618999  0.48
2002 Hildesheim J, Fornace AJ. Gadd45a: An elusive yet attractive candidate gene in pancreatic cancer Clinical Cancer Research. 8: 2475-2479. PMID 12171872  0.48
2002 Amundson SA, Patterson A, Do KT, Fornace AJ. A nucleotide excision repair master-switch: p53 regulated coordinate induction of global genomic repair genes Cancer Biology and Therapy. 1: 145-149. PMID 12170774 DOI: 10.4161/Cbt.59  0.48
2002 Bulavin DV, Demidov ON, Saito S, Kauraniemi P, Phillips C, Amundson SA, Ambrosino C, Sauter G, Nebreda AR, Anderson CW, Kallioniemi A, Fornace AJ, Appella E. Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity Nature Genetics. 31: 210-215. PMID 12021785 DOI: 10.1038/Ng894  0.48
2002 Salvador JM, Hollander MC, Nguyen AT, Kopp JB, Barisoni L, Moore JK, Ashwell JD, Fornace AJ. Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome Immunity. 16: 499-508. PMID 11970874 DOI: 10.1016/S1074-7613(02)00302-3  0.48
2002 Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ, DiStefano PS, Chiang LW, Greenberg ME. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science (New York, N.Y.). 296: 530-4. PMID 11964479 DOI: 10.1126/Science.1068712  0.48
2002 Fornace AJ, Amundson SA, Do KT, Meltzer P, Trent J, Bittner M. Stress-gene induction by low-dose gamma irradiation Military Medicine. 167: 13-15. PMID 11873496 DOI: 10.1093/Milmed/167.Suppl_1.13  0.48
2002 Bulavin DV, Amundson SA, Fornace AJ. p38 and Chk1 kinases: Different conductors for the G2/M checkpoint symphony Current Opinion in Genetics and Development. 12: 92-97. PMID 11790561 DOI: 10.1016/S0959-437X(01)00270-2  0.48
2002 Dmitrieva NI, Bulavin DV, Fornace AJ, Burg MB. Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase Proceedings of the National Academy of Sciences of the United States of America. 99: 184-189. PMID 11756692 DOI: 10.1073/Pnas.231623498  0.48
2002 Smith ML, Fornace AJ. Chemotherapeutic targeting of p53 Cancer Biology and Therapy. 1: 56-57. DOI: 10.4161/Cbt.1.1.42  0.48
2002 Hollander MC, Fornace AJ. Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a Oncogene. 21: 6228-6233. DOI: 10.1038/Sj.Onc.1205774  0.48
2001 Kovalsky O, Lung FDT, Roller PP, Fornace AJ. Oligomerization of Human Gadd45a Protein Journal of Biological Chemistry. 276: 39330-39339. PMID 11498536 DOI: 10.1074/Jbc.M105115200  0.48
2001 Bulavin DV, Higashimoto Y, Popoff IJ, Gaarde WA, Basrur V, Potapova O, Appella E, Fornace AJ. Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase Nature. 411: 102-107. PMID 11333986 DOI: 10.1038/35075107  0.48
2001 Christine Hollander M, Saeed Sheikh M, Yu K, Zhan Q, Iglesias M, Woodworth C, Fornace AJ. Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors International Journal of Cancer. 96: 22-31. PMID 11241327 DOI: 10.1002/1097-0215(20010220)96:1<22::AID-IJC3>3.0.CO;2-K  0.48
2000 Jin S, Zhao H, Fan F, Blanck P, Fan W, Colchagie AB, Fornace AJ, Zhan Q. BRCA1 activation of the GADD45 promoter Oncogene. 19: 4050-4057. PMID 10962562 DOI: 10.1038/Sj.Onc.1203759  0.48
2000 Sheikh MS, Fornace AJ. Death and decoy receptors and p53-mediated apoptosis Leukemia. 14: 1509-1513. PMID 10942251  0.48
2000 Meng RD, McDonald ER, Sheikh MS, Fornace AJ, El-Deiry WS. The TRAIL Decoy Receptor TRUNDD (DcR2, TRAIL-R4) Is Induced by Adenovirus-p53 Overexpression and Can Delay TRAIL-, p53-, and KILLER/DR5-Dependent Colon Cancer Apoptosis Molecular Therapy. 1: 130-144. PMID 10933923 DOI: 10.1006/Mthe.2000.0025  0.48
2000 Zhao H, Jin S, Antinore MJ, Lung FDT, Fan F, Blanck P, Roller P, Fornace AJ, Zhan Q. The central region of Gadd45 is required for its interaction with p21/WAF1 Experimental Cell Research. 258: 92-100. PMID 10912791 DOI: 10.1006/Excr.2000.4906  0.48
2000 Elizondo G, Fernandez-Salguero P, Sheikh MS, Kim GY, Fornace AJ, Lee KS, Gonzalez FJ. Altered cell cycle control at the G2/M phases in aryl hydrocarbon receptor-null embryo fibroblast Molecular Pharmacology. 57: 1056-1063. PMID 10779392  0.48
2000 Smith ML, Ford JM, Hollander MC, Bortnick RA, Amundson SA, Seo YR, Deng CX, Hanawalt PC, Fornace AJ. p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes. Molecular and Cellular Biology. 20: 3705-14. PMID 10779360 DOI: 10.1128/Mcb.20.10.3705-3714.2000  0.48
2000 Jin S, Antinore MJ, Lung FDT, Dong X, Zhao H, Fan F, Colchagie AB, Blanck P, Roller PP, Fornace AJ, Zhan Q. The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression Journal of Biological Chemistry. 275: 16602-16608. PMID 10747892 DOI: 10.1074/Jbc.M000284200  0.48
2000 Sheikh MS, Fornace AJ. Role of p53 family members in apoptosis Journal of Cellular Physiology. 182: 171-181. PMID 10623880 DOI: 10.1002/(Sici)1097-4652(200002)182:2<171::Aid-Jcp5>3.0.Co;2-3  0.48
2000 Sheikh MS, Hollander MC, Fornace AJ. Role of Gadd45 in apoptosis Biochemical Pharmacology. 59: 43-45. PMID 10605933 DOI: 10.1016/S0006-2952(99)00291-9  0.48
1999 Goldwasser F, Bae I, Pommier Y, Fornace AJ. Evidence of a reduced DNA topoisomerase II mRNA expression after ionizing radiation Anticancer Research. 19: 3167-3171. PMID 10652607  0.48
1999 Bulavin DV, Saito S, Hollander MC, Sakaguchi K, Anderson CW, Appella E, Fornace AJ. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation Embo Journal. 18: 6845-6854. PMID 10581258 DOI: 10.1093/Emboj/18.23.6845  0.48
1999 Sheikh MS, Fornace AJ. Regulation of translation initiation following stress Oncogene. 18: 6121-6128. PMID 10557103 DOI: 10.1038/Sj.Onc.1203131  0.48
1999 Hollander MC, Sheikh MS, Bulavin DV, Lundgren K, Augeri-Henmueller L, Shehee R, Molinaro TA, Kim KE, Tolosa E, Ashwell JD, Rosenberg MP, Zhan Q, Fernández-Salguero PM, Morgan WF, Deng CX, ... Fornace AJ, et al. Genomic instability in Gadd45a-deficient mice Nature Genetics. 23: 176-184. PMID 10508513 DOI: 10.1038/13802  0.48
1999 Adler HT, Chinery R, Wu DY, Kussick SJ, Payne JM, Fornace AJ, Tkachuk DC. Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins Molecular and Cellular Biology. 19: 7050-7060. PMID 10490642 DOI: 10.1128/Mcb.19.10.7050  0.48
1999 Graunke DM, Fornace AJ, Pieper RO. Presetting of chromatin structure and transcription factor binding poise the human GADD45 gene for rapid transcriptional up-regulation Nucleic Acids Research. 27: 3881-3890. PMID 10481028 DOI: 10.1093/Nar/27.19.3881  0.48
1999 Rishi AK, Sun RJ, Gao Y, Hsu CKA, Gerald TM, Sheikh MS, Dawson MI, Reichert U, Shroot B, Fornace AJ, Brewer G, Fontana JA. Post-transcriptional regulation of the DNA damage-inducible gadd45 gene in human breast carcinoma cells exposed to a novel retinoid CD437 Nucleic Acids Research. 27: 3111-3119. PMID 10454607 DOI: 10.1093/Nar/27.15.3111  0.48
1999 Amundson SA, Do KT, Fornace AJ. Induction of stress genes by low doses of gamma rays Radiation Research. 152: 225-231. PMID 10453082 DOI: 10.2307/3580321  0.48
1999 Fornace AJ, Amundson SA, Bittner M, Myers TG, Meltzer P, Weinsten JN, Trent J. The complexity of radiation stress responses: Analysis by informatics and functional genomics approaches Gene Expression. 7: 387-400. PMID 10440239  0.48
1999 Sheikh MS, Huang Y, Fernandez-Salas EA, El-Deiry WS, Friess H, Amundson S, Yin J, Meltzer SJ, Holbrook NJ, Fornace AJ. The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract. Oncogene. 18: 4153-9. PMID 10435597 DOI: 10.1038/Sj.Onc.1202763  0.48
1999 Amundson SA, Bittner M, Chen Y, Trent J, Meltzer P, Fornace AJ. Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses Oncogene. 18: 3666-3672. PMID 10380890 DOI: 10.1038/Sj.Onc.1202676  0.48
1999 Huang Y, Sheikh MS, Fornace AJ, Holbrook NJ. Serine protease inhibitor TPCK prevents Taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells Oncogene. 18: 3431-3439. PMID 10376521 DOI: 10.1038/Sj.Onc.1202685  0.48
1999 Zhan Q, Antinore MJ, Wang XW, Carrier F, Smith ML, Harris CC, Fornace AJ. Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45 Oncogene. 18: 2892-2900. PMID 10362260 DOI: 10.1038/Sj.Onc.1202667  0.48
1999 Sheikh MS, Fernandez-Salas E, Yu M, Hussain A, Dinman JD, Peltz SW, Huang Y, Fornace AJ. Cloning and characterization of a human genotoxic and endoplasmic reticulum stress-inducible cDNA that encodes translation initiation factor 1(eIF1(A121/SUI1)) Journal of Biological Chemistry. 274: 16487-16493. PMID 10347211 DOI: 10.1074/Jbc.274.23.16487  0.48
1999 Wang XW, Zhan Q, Coursen JD, Khan MA, Kontny HU, Yu L, Hollander MC, O'Connor PM, Fornace AJ, Harris CC. GADD45 induction of a G2/M cell cycle checkpoint Proceedings of the National Academy of Sciences of the United States of America. 96: 3706-3711. PMID 10097101 DOI: 10.1073/Pnas.96.7.3706  0.48
1999 Carrier F, Georgel PT, Pourquier P, Blake M, Kontny HU, Antinore MJ, Gariboldi M, Myers TG, Weinstein JN, Pommier Y, Fornace AJ. Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin Molecular and Cellular Biology. 19: 1673-1685. PMID 10022855 DOI: 10.1128/Mcb.19.3.1673  0.48
1999 Zhan Q, Kontny U, Iglesias M, Alamo I, Yu K, Hollander MC, Woodworth CD, Fornace AJ. Inhibitory effect of Bcl-2 on p53-mediated transactivation following genotoxic stress Oncogene. 18: 297-304. PMID 9927186 DOI: 10.1038/Sj.Onc.1202310  0.48
1998 Amundson SA, Myers TG, Fornace AJ. Roles for p53 in growth arrest and apoptosis: Putting on the brakes after genotoxic stress Oncogene. 17: 3287-3299. PMID 9916991 DOI: 10.1038/Sj.Onc.1202576  0.48
1998 Sheikh MS, Antinore MJ, Huang Y, Fornace AJ. Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1 Oncogene. 17: 2555-2563. PMID 9840918 DOI: 10.1038/Sj.Onc.1202292  0.48
1998 Amundson SA, Zhan Q, Penn LZ, Fornace AJ. Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents Oncogene. 17: 2149-2154. PMID 9811446  0.48
1998 Zaher H, Fernandez-Salguero PM, Letterio J, Sheikh MS, Fornace AJ, Roberts AB, Gonzalez FJ. The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-β and apoptosis Molecular Pharmacology. 54: 313-321. PMID 9687573 DOI: 10.1124/Mol.54.2.313  0.48
1998 Smith ML, Bortnick RA, Sheikh MS, Fornace AJ. Chromatin relaxation by overexpression of mutant p53, HPV16-E6, or cyclin G transgenes. Experimental Cell Research. 242: 235-43. PMID 9665821 DOI: 10.1006/Excr.1998.4078  0.48
1998 Carrier F, Zhan Q, Alamo I, Hanaoka F, Fornace AJ. Evidence for distinct kinase-mediated pathways in gadd gene responses Biochemical Pharmacology. 55: 853-861. PMID 9586958 DOI: 10.1016/S0006-2952(97)00592-3  0.48
1998 Zhan Q, Chen IT, Antinore MJ, Fornace AJ. Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA binding Molecular and Cellular Biology. 18: 2768-2778. PMID 9566896 DOI: 10.1128/Mcb.18.5.2768  0.48
1998 Sheikh MS, Burns TF, Huang Y, Wu GS, Amundson S, Brooks KS, Fornace AJ, El-Deiry WS. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor Cancer Research. 58: 1593-1598. PMID 9563466  0.48
1997 Sheikh MS, Carrier F, Papathanasiou MA, Hollander MC, Zhan Q, Yu K, Fornace AJ. Identification of several human homologs of hamster DNA damage-inducible transcripts. Cloning and characterization of a novel UV-inducible cDNA that codes for a putative RNA-binding protein Journal of Biological Chemistry. 272: 26720-26726. PMID 9334257 DOI: 10.1074/Jbc.272.42.26720  0.48
1997 O'Connor PM, Jackman J, Bae I, Myers TG, Fan S, Mutoh M, Scudiero DA, Monks A, Sausville EA, Weinstein JN, Friend S, Fornace AJ, Kohn KW. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents Cancer Research. 57: 4285-4300. PMID 9331090  0.48
1997 Sheikh MS, Carrier F, Johnson AC, Ogdon SE, Fornace AJ. Identification of an additional p53-responsive site in the human epidermal growth factor receptor gene promotor Oncogene. 15: 1095-1101. PMID 9285564 DOI: 10.1038/Sj.Onc.1201264  0.48
1997 Marhin WW, Chen S, Facchini LM, Fornace AJ, Penn LZ. Myc represses the growth arrest gene gadd45 Oncogene. 14: 2825-2834. PMID 9190899 DOI: 10.1038/Sj.Onc.1201138  0.48
1997 Fan S, Chang JK, Smith ML, Duba D, Fornace AJ, O'Connor PM. Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard Oncogene. 14: 2127-2136. PMID 9174048 DOI: 10.1038/Sj.Onc.1201052  0.48
1997 Hollander MC, Zhan Q, Bae I, Fornace AJ. Mammalian GADD34, an apoptosis- and DNA damage-inducible gene Journal of Biological Chemistry. 272: 13731-13737. PMID 9153226 DOI: 10.1074/Jbc.272.21.13731  0.48
1997 Sheikh MS, Chen YQ, Smith ML, Fornace AJ. Role of p21(Waf1/Cip1/Sdi1) in cell death and DNA repair as studied using a tetracycline-inducible system in p53-deficient cells Oncogene. 14: 1875-1882. PMID 9150394 DOI: 10.1038/Sj.Onc.1201004  0.48
1997 Zhan Q, Bieszczad CK, Bae I, Fornace AJ, Craig RW. Induction of BCL2 family member MCL1 as an early response to DNA damage Oncogene. 14: 1031-1039. PMID 9070651 DOI: 10.1038/Sj.Onc.1200927  0.48
1997 Smith ML, Kontny HU, Bortnick R, Fornace AJ. The p53-regulated cyclin G gene promotes cell growth: P53 downstream effectors cyclin G and Gadd45 exert different effects on cisplatin chemosensitivity Experimental Cell Research. 230: 61-68. PMID 9013707 DOI: 10.1006/Excr.1996.3402  0.48
1997 Weinstein JN, Myers TG, O'Connor PM, Friend SH, Fornace AJ, Kohn KW, Fojo T, Bates SE, Rubinstein LV, Anderson NL, Buolamwini JK, Van Osdol WW, Monks AP, Scudiero DA, Sausville EA, et al. An information-intensive approach to the molecular pharmacology of cancer Science. 275: 343-349. PMID 8994024 DOI: 10.1126/Science.275.5298.343  0.48
1996 Saeed Sheikh M, Garcia M, Zhan Q, Liu Y, Fornace AJ. Cell cycle-independent regulation of p21(Waf1)/(Cip1) and retinoblastoma protein during okadaic acid-induced apoptosis is coupled with induction of bax protein in human breast carcinoma cells Cell Growth and Differentiation. 7: 1599-1607. PMID 8959327  0.48
1996 Zhan Q, Alamo I, Yu K, Boise LH, Cherney B, Tosato G, O'Connor PM, Fornace AJ. The apoptosis-associated γ-ray response of BCL-X(L) depends on normal p53 function Oncogene. 13: 2287-2293. PMID 8950997  0.48
1996 Smith ML, Kontny HU, Zhan Q, Sreenath A, O'Connor PM, Fornace AJ. Antisense GADD45 expression results in decreased DNA repair and sensitizes cells to u.v.-irradiation or cisplatin Oncogene. 13: 2255-2263. PMID 8950993  0.48
1996 Holbrook NJ, Liu Y, Fornace AJ. Signaling events controlling the molecular response to genotoxic stress Exs. 77: 273-288. PMID 8856980  0.48
1996 Vairapandi M, Balliet AG, Fornace AJ, Hoffman B, Liebermann DA. The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21(WAF1/CIP1) Oncogene. 12: 2579-2594. PMID 8700517  0.48
1996 Smith ML, Fornace AJ. Mammalian DNA damage-inducible genes associated with growth arrest and apoptosis Mutation Research - Reviews in Genetic Toxicology. 340: 109-124. PMID 8692176 DOI: 10.1016/S0165-1110(96)90043-3  0.48
1996 Carrier F, Bae I, Smith ML, Ayers DM, Fornace AJ. Characterization of the GADD45 response to ionizing radiation in WI-L2-NS cells, a p53 mutant cell line Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 352: 79-86. PMID 8676920 DOI: 10.1016/0027-5107(95)00255-3  0.48
1996 Liebermann DA, Myers A, Weinhouse S, Nowell PC, Fornace AJ, Kastan MB, White E, Tisty TD, Ihle JN, Waxman S, Reddy P. Molecular biology of normal development, malignancy and its suppression Oncogene. 12: 2247-2250. PMID 8668352  0.48
1996 Chen IT, Akamatsu M, Smith ML, Lung FDT, Duba D, Roller PP, Fornace AJ, O'Connor PM. Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction Oncogene. 12: 595-607. PMID 8637717  0.48
1994 Zhan Q, Lord KA, Alamo I, Hollander MC, Carrier F, Ron D, Kohn KW, Hoffman B, Liebermann DA, Fornace AJ. The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Molecular and Cellular Biology. 14: 2361-71. PMID 8139541 DOI: 10.1128/Mcb.14.4.2361  0.48
1994 Graeber TG, Peterson JF, Tsai M, Monica K, Fornace AJ, Giaccia AJ. Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Molecular and Cellular Biology. 14: 6264-77. PMID 8065358 DOI: 10.1128/Mcb.14.9.6264  0.48
1992 Fornace AJ, Jackman J, Hollander MC, Hoffman-Liebermann B, Liebermann DA. Genotoxic-stress-response genes and growth-arrest genes gadd, MyD, and other genes induced by treatments eliciting growth arrest Annals of the New York Academy of Sciences. 663: 139-153. PMID 1482047 DOI: 10.1111/J.1749-6632.1992.Tb38657.X  0.48
1990 Schilder RJ, Hall L, Monks A, Handel LM, Fornace AJ, Ozols RF, Fojo AT, Hamilton TC. Metallothionein gene expression and resistance to cisplatin in human ovarian cancer International Journal of Cancer. 45: 416-422. PMID 2307530 DOI: 10.1002/Ijc.2910450306  0.48
1990 Bhatia K, Pommier Y, Giri C, Fornace AJ, Imaizumi M, Breitman TR, Cherney BW, Smulson ME. Expression of the poly(ADP-ribose) polymerase gene following natural and induced DNA strand breakage and effect of hyperexpression on DNA repair. Carcinogenesis. 11: 123-8. PMID 2104780 DOI: 10.1093/Carcin/11.1.123  0.48
1988 Nagasawa H, Fornace AJ, Little JB. Recovery of mitomycin C-treated mouse 10T1/2 cells during confluent holding. Mutation Research. 198: 153-60. PMID 3127697 DOI: 10.1016/0027-5107(88)90050-4  0.4
1985 Crabtree GR, Comeau CM, Fowlkes DM, Fornace AJ, Malley JD, Kant JA. Evolution and structure of the fibrinogen genes. Random insertion of introns or selective loss? Journal of Molecular Biology. 185: 1-19. PMID 4046033 DOI: 10.1016/0022-2836(85)90179-2  0.48
1985 Yarosh DB, Fornace AJ, Day RS. Human O6-alkylguanine-DNA alkyltransferase fails to repair O4-methylthymine and methyl phosphotriesters in DNA as efficiently as does the alkyltransferase from Escherichia coli. Carcinogenesis. 6: 949-53. PMID 3893783 DOI: 10.1093/Carcin/6.7.949  0.48
1985 Kant JA, Fornace AJ, Saxe D, Simon MI, McBride OW, Crabtree GR. Evolution and organization of the fibrinogen locus on chromosome 4: Gene duplication accompanied by transposition and inversion Proceedings of the National Academy of Sciences of the United States of America. 82: 2344-2348. PMID 2986113 DOI: 10.1073/Pnas.82.8.2344  0.48
1984 Holbrook NJ, Smith KA, Fornace AJ, Comeau CM, Wiskocil RL, Crabtree GR. T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 1634-8. PMID 6608729 DOI: 10.1073/Pnas.81.6.1634  0.48
1984 Fornace AJ, Cummings DE, Comeau CM, Kant JA, Crabtree GR. Single-copy inverted repeats associated with regional genetic duplications in gamma fibrinogen and immunoglobulin genes. Science (New York, N.Y.). 224: 161-4. PMID 6322310 DOI: 10.1126/Science.6322310  0.48
1983 Henson P, Fornace AJ, Little JB. Normal repair of ultraviolet-induced DNA damage in a hypersensitive strain of fibroblasts from a patient with Gardner's syndrome. Mutation Research. 112: 383-95. PMID 6656799 DOI: 10.1016/0167-8817(83)90031-7  0.48
1980 Fornace AJ, Little JB. Malignant transformation by the DNA-protein crosslinking agent trans-Pt(II) diamminedichloride. Carcinogenesis. 1: 989-94. PMID 11272115 DOI: 10.1093/Carcin/1.12.989  0.92
1980 Fornace AJ, Nagasawa H, Little JB. Relationship of DNA repair to chromosome aberrations, sister-chromatid exchanges and survival during liquid-holding recovery in X-irradiated mammalian cells. Mutation Research. 70: 323-36. PMID 7383039 DOI: 10.1016/0027-5107(80)90022-6  0.32
1980 Fornace AJ, Nagasawa H, Little JB. Relationship of DNA repair and chromosome aberrations to potentially lethal damage repair in X-irradiated mammalian cells. Basic Life Sciences. 15: 267-83. PMID 7213316 DOI: 10.1007/978-1-4684-3842-0_18  0.4
1980 Fornace AJ, Little JB. Normal repair of DNA single-strand breaks in patients with ataxia telangiectasia. Biochimica Et Biophysica Acta. 607: 432-7. PMID 6156701 DOI: 10.1016/0005-2787(80)90153-7  0.96
1979 Fornace AJ, Little JB, Weichselbaum RR. DNA repair in a Fanconi's anemia fibroblast cell strain. Biochimica Et Biophysica Acta. 561: 99-109. PMID 420857 DOI: 10.1016/0005-2787(79)90494-5  0.56
1979 Fornace AJ, Little JB. DNA-protein cross-linking by chemical carcinogens in mammalian cells. Cancer Research. 39: 704-10. PMID 106958  0.96
1977 Fornace AJ, Little JB. DNA crosslinking induced by x-rays and chemical agents. Biochimica Et Biophysica Acta. 477: 343-55. PMID 889829 DOI: 10.1016/0005-2787(77)90253-2  0.92
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