| Year |
Citation |
Score |
| 2023 |
Polák P, Garland W, Rathore O, Schmid M, Salerno-Kochan A, Jakobsen L, Gockert M, Gerlach P, Silla T, Andersen JS, Conti E, Jensen TH. Dual agonistic and antagonistic roles of ZC3H18 provide for co-activation of distinct nuclear RNA decay pathways. Cell Reports. 42: 113325. PMID 37889751 DOI: 10.1016/j.celrep.2023.113325 |
0.452 |
|
| 2023 |
Keidel A, Kögel A, Reichelt P, Kowalinski E, Schäfer IB, Conti E. Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Molecular Cell. 83: 4093-4105.e7. PMID 37879335 DOI: 10.1016/j.molcel.2023.09.037 |
0.856 |
|
| 2023 |
Bonneau F, Basquin J, Steigenberger B, Schäfer T, Schäfer IB, Conti E. Nuclear mRNPs are compact particles packaged with a network of proteins promoting RNA-RNA interactions. Genes & Development. PMID 37399331 DOI: 10.1101/gad.350630.123 |
0.744 |
|
| 2023 |
Rouvière JO, Salerno-Kochan A, Lykke-Andersen S, Garland W, Dou Y, Rathore O, Molska EŠ, Wu G, Schmid M, Bugai A, Jakobsen L, Žumer K, Cramer P, Andersen JS, Conti E, et al. ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts. Molecular Cell. 83: 2240-2257.e6. PMID 37329882 DOI: 10.1016/j.molcel.2023.05.028 |
0.478 |
|
| 2022 |
Mauxion F, Basquin J, Ozgur S, Rame M, Albrecht J, Schäfer I, Séraphin B, Conti E. The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions. Cell Reports. 111902. PMID 36586408 DOI: 10.1016/j.celrep.2022.111902 |
0.686 |
|
| 2022 |
Gerlach P, Garland W, Lingaraju M, Salerno-Kochan A, Bonneau F, Basquin J, Jensen TH, Conti E. Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome. Molecular Cell. PMID 35688157 DOI: 10.1016/j.molcel.2022.04.011 |
0.545 |
|
| 2022 |
Schmidt M, Kluge F, Sandmeir F, Kühn U, Schäfer P, Tüting C, Ihling C, Conti E, Wahle E. Reconstitution of 3' end processing of mammalian pre-mRNA reveals a central role of RBBP6. Genes & Development. 36: 195-209. PMID 35177537 DOI: 10.1101/gad.349217.121 |
0.457 |
|
| 2022 |
Kögel A, Keidel A, Bonneau F, Schäfer IB, Conti E. The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Molecular Cell. 82: 756-769.e8. PMID 35120588 DOI: 10.1016/j.molcel.2022.01.009 |
0.759 |
|
| 2021 |
Langer LM, Bonneau F, Gat Y, Conti E. Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife. 10. PMID 34698635 DOI: 10.7554/eLife.72353 |
0.307 |
|
| 2020 |
Schuller SK, Schuller JM, Prabu JR, Baumgärtner M, Bonneau F, Basquin J, Conti E. Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife. 9. PMID 33191913 DOI: 10.7554/eLife.61467 |
0.435 |
|
| 2020 |
Lingaraju M, Schuller JM, Falk S, Gerlach P, Bonneau F, Basquin J, Benda C, Conti E. To Process or to Decay: A Mechanistic View of the Nuclear RNA Exosome. Cold Spring Harbor Symposia On Quantitative Biology. PMID 32493762 DOI: 10.1101/Sqb.2019.84.040295 |
0.808 |
|
| 2020 |
Langer LM, Gat Y, Bonneau F, Conti E. Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. Elife. 9. PMID 32469312 DOI: 10.7554/Elife.57127 |
0.389 |
|
| 2020 |
Busetto V, Barbosa I, Basquin J, Marquenet É, Hocq R, Hennion M, Paternina JA, Namane A, Conti E, Bensaude O, Le Hir H. Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes. Nucleic Acids Research. PMID 32329775 DOI: 10.1093/Nar/Gkaa267 |
0.433 |
|
| 2020 |
Keidel A, Conti E, Falk S. Purification and Reconstitution of the S. cerevisiae TRAMP and Ski Complexes for Biochemical and Structural Studies. Methods in Molecular Biology (Clifton, N.J.). 2062: 491-513. PMID 31768992 DOI: 10.1007/978-1-4939-9822-7_24 |
0.812 |
|
| 2020 |
Langer LM, Gat Y, Bonneau F, Conti E. Author response: Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity Elife. DOI: 10.7554/Elife.57127.Sa2 |
0.336 |
|
| 2019 |
Gat Y, Schuller JM, Lingaraju M, Weyher E, Bonneau F, Strauss M, Murray PJ, Conti E. InsP binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. Nature Structural & Molecular Biology. PMID 31792449 DOI: 10.1038/S41594-019-0342-7 |
0.424 |
|
| 2019 |
Lingaraju M, Johnsen D, Schlundt A, Langer LM, Basquin J, Sattler M, Heick Jensen T, Falk S, Conti E. The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs. Nature Communications. 10: 3393. PMID 31358741 DOI: 10.1038/S41467-019-11339-X |
0.814 |
|
| 2019 |
Schäfer IB, Yamashita M, Schuller JM, Schüssler S, Reichelt P, Strauss M, Conti E. Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase. Cell. PMID 31104843 DOI: 10.1016/J.Cell.2019.04.013 |
0.749 |
|
| 2018 |
Gerlach P, Schuller JM, Bonneau F, Basquin J, Reichelt P, Falk S, Conti E. Distinct and evolutionary conserved structural features of the human nuclear exosome complex. Elife. 7. PMID 30047866 DOI: 10.7554/Elife.38686 |
0.827 |
|
| 2018 |
Schuller JM, Falk S, Fromm L, Hurt E, Conti E. Structure of the nuclear exosome captured on a maturing preribosome. Science (New York, N.Y.). PMID 29519915 DOI: 10.1126/Science.Aar5428 |
0.814 |
|
| 2018 |
Gerlach P, Schuller JM, Bonneau F, Basquin J, Reichelt P, Falk S, Conti E. Author response: Distinct and evolutionary conserved structural features of the human nuclear exosome complex Elife. DOI: 10.7554/Elife.38686.026 |
0.734 |
|
| 2018 |
Falk S, Conti E. Das RNA-Exosom – eine molekulare Maschine für den RNA-Abbau Biospektrum. 24: 134-137. DOI: 10.1007/S12268-018-0896-7 |
0.797 |
|
| 2017 |
Fromm L, Falk S, Flemming D, Schuller JM, Thoms M, Conti E, Hurt E. Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome. Nature Communications. 8: 1787. PMID 29176610 DOI: 10.1038/S41467-017-01786-9 |
0.773 |
|
| 2017 |
Falk S, Tants JN, Basquin J, Thoms M, Hurt E, Sattler M, Conti E. Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the pre-ribosomal protein Nop53. Rna (New York, N.Y.). PMID 28883156 DOI: 10.1261/Rna.062901.117 |
0.792 |
|
| 2017 |
Falk S, Bonneau F, Ebert J, Kögel A, Conti E. Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase. Cell Reports. 20: 2279-2286. PMID 28877463 DOI: 10.1016/J.Celrep.2017.08.033 |
0.831 |
|
| 2017 |
Leonaitė B, Han Z, Basquin J, Bonneau F, Libri D, Porrua O, Conti E. Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase family. The Embo Journal. PMID 28408439 DOI: 10.15252/Embj.201696174 |
0.552 |
|
| 2017 |
Li L, Lingaraju M, Basquin C, Basquin J, Conti E. Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins. Rna (New York, N.Y.). PMID 28389433 DOI: 10.1261/Rna.061200.117 |
0.483 |
|
| 2016 |
Schmidt C, Kowalinski E, Shanmuganathan V, Defenouillère Q, Braunger K, Heuer A, Pech M, Namane A, Berninghausen O, Fromont-Racine M, Jacquier A, Conti E, Becker T, Beckmann R. The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex. Science (New York, N.Y.). 354: 1431-1433. PMID 27980209 DOI: 10.1126/Science.Aaf7520 |
0.827 |
|
| 2016 |
Falk S, Finogenova K, Melko M, Benda C, Lykke-Andersen S, Jensen TH, Conti E. Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors. Nature Communications. 7: 13573. PMID 27905398 DOI: 10.1038/Ncomms13573 |
0.82 |
|
| 2016 |
Kowalinski E, Kögel A, Ebert J, Reichelt P, Stegmann E, Habermann B, Conti E. Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex. Molecular Cell. PMID 27345150 DOI: 10.1016/J.Molcel.2016.05.028 |
0.835 |
|
| 2016 |
Nakel K, Bonneau F, Basquin C, Habermann B, Eckmann CR, Conti E. Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity. Rna (New York, N.Y.). PMID 27288313 DOI: 10.1261/Rna.056598.116 |
0.521 |
|
| 2016 |
Vukovic L, Chipot C, Makino DL, Conti E, Schulten K. Molecular mechanism of processive 3' to 5' RNA translocation in the active subunit of the RNA exosome complex. Journal of the American Chemical Society. PMID 26928279 DOI: 10.1021/Jacs.5B12065 |
0.546 |
|
| 2015 |
Prabu JR, Müller M, Thomae AW, Schüssler S, Bonneau F, Becker PB, Conti E. Structure of the RNA Helicase MLE Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling. Molecular Cell. 60: 487-99. PMID 26545078 DOI: 10.1016/J.Molcel.2015.10.011 |
0.608 |
|
| 2015 |
Ozgur S, Basquin J, Kamenska A, Filipowicz W, Standart N, Conti E. Structure of a Human 4E-T/DDX6/CNOT1 Complex Reveals the Different Interplay of DDX6-Binding Proteins with the CCR4-NOT Complex. Cell Reports. 13: 703-11. PMID 26489469 DOI: 10.1016/J.Celrep.2015.09.033 |
0.411 |
|
| 2015 |
Makino DL, Schuch B, Stegmann E, Baumgärtner M, Basquin C, Conti E. RNA degradation paths in a 12-subunit nuclear exosome complex. Nature. 524: 54-8. PMID 26222026 DOI: 10.1038/Nature14865 |
0.614 |
|
| 2015 |
Nakel K, Bonneau F, Eckmann CR, Conti E. Structural basis for the activation of the C. elegans noncanonical cytoplasmic poly(A)-polymerase GLD-2 by GLD-3. Proceedings of the National Academy of Sciences of the United States of America. 112: 8614-9. PMID 26124149 DOI: 10.1073/Pnas.1504648112 |
0.583 |
|
| 2015 |
Sharma K, Hrle A, Kramer K, Sachsenberg T, Staals RH, Randau L, Marchfelder A, van der Oost J, Kohlbacher O, Conti E, Urlaub H. Analysis of protein-RNA interactions in CRISPR proteins and effector complexes by UV-induced cross-linking and mass spectrometry. Methods (San Diego, Calif.). PMID 26071038 DOI: 10.1016/J.Ymeth.2015.06.005 |
0.564 |
|
| 2015 |
Kowalinski E, Schuller A, Green R, Conti E. Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases. Structure (London, England : 1993). PMID 26051716 DOI: 10.1016/J.Str.2015.04.018 |
0.783 |
|
| 2015 |
Bhaskar V, Basquin J, Conti E. Architecture of the ubiquitylation module of the yeast Ccr4-Not complex. Structure (London, England : 1993). 23: 921-8. PMID 25914052 DOI: 10.1016/J.Str.2015.03.011 |
0.443 |
|
| 2015 |
Ozgur S, Buchwald G, Falk S, Chakrabarti S, Prabu JR, Conti E. The conformational plasticity of eukaryotic RNA-dependent ATPases. The Febs Journal. 282: 850-63. PMID 25645110 DOI: 10.1111/Febs.13198 |
0.844 |
|
| 2015 |
Ozgur S, Buchwald G, Falk S, Chakrabarti S, Prabu JR, Conti E. The conformational plasticity of eukaryotic RNA-dependent ATPases Febs Journal. DOI: 10.1111/febs.13198 |
0.806 |
|
| 2015 |
Vukovic L, Makino DL, Chipot C, Conti E, Schulten K. Molecular Mechanism of Processive 3’ to 5’ RNA Translocation in the RNA Exosome Complex Biophysical Journal. 108: 400a. DOI: 10.1016/J.Bpj.2014.11.2192 |
0.543 |
|
| 2014 |
Hrle A, Maier LK, Sharma K, Ebert J, Basquin C, Urlaub H, Marchfelder A, Conti E. Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. Rna Biology. 11: 1072-82. PMID 25483036 DOI: 10.4161/Rna.29893 |
0.484 |
|
| 2014 |
Schuch B, Feigenbutz M, Makino DL, Falk S, Basquin C, Mitchell P, Conti E. The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase. The Embo Journal. 33: 2829-46. PMID 25319414 DOI: 10.15252/Embj.201488757 |
0.799 |
|
| 2014 |
Benda C, Ebert J, Scheltema RA, Schiller HB, Baumgärtner M, Bonneau F, Mann M, Conti E. Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4. Molecular Cell. 56: 43-54. PMID 25280103 DOI: 10.1016/J.Molcel.2014.09.002 |
0.567 |
|
| 2014 |
Falk S, Weir JR, Hentschel J, Reichelt P, Bonneau F, Conti E. The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities. Molecular Cell. 55: 856-67. PMID 25175027 DOI: 10.1016/J.Molcel.2014.07.020 |
0.803 |
|
| 2014 |
van de Waterbeemd M, Lössl P, Gautier V, Marino F, Yamashita M, Conti E, Scholten A, Heck AJ. Simultaneous assessment of kinetic, site-specific, and structural aspects of enzymatic protein phosphorylation. Angewandte Chemie (International Ed. in English). 53: 9660-4. PMID 25044833 DOI: 10.1002/Anie.201404637 |
0.359 |
|
| 2014 |
Chakrabarti S, Bonneau F, Schüssler S, Eppinger E, Conti E. Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6 Nucleic Acids Research. 42: 9447-9460. PMID 25013172 DOI: 10.1093/Nar/Gku578 |
0.629 |
|
| 2014 |
Schäfer IB, Rode M, Bonneau F, Schüssler S, Conti E. The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase Nature Structural and Molecular Biology. 21: 591-598. PMID 24880344 DOI: 10.1038/Nsmb.2834 |
0.764 |
|
| 2014 |
Mathys H, Basquin J, Ozgur S, Czarnocki-Cieciura M, Bonneau F, Aartse A, Dziembowski A, Nowotny M, Conti E, Filipowicz W. Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression. Molecular Cell. 54: 751-65. PMID 24768538 DOI: 10.1016/J.Molcel.2014.03.036 |
0.405 |
|
| 2014 |
Plagens A, Tripp V, Daume M, Sharma K, Klingl A, Hrle A, Conti E, Urlaub H, Randau L. In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex. Nucleic Acids Research. 42: 5125-38. PMID 24500198 DOI: 10.1093/Nar/Gku120 |
0.398 |
|
| 2014 |
Schuch B, Feigenbutz M, Makino DL, Falk S, Basquin C, Mitchell P, Conti E. The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase Embo Journal. 33: 2829-2846. DOI: 10.15252/embj.201488757 |
0.689 |
|
| 2014 |
Falk S, Weir J, Hentschel J, Reichelt P, Bonneau F, Conti E. The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities Molecular Cell. DOI: 10.1016/j.molcel.2014.07.020 |
0.691 |
|
| 2014 |
van de Waterbeemd M, Lössl P, Gautier V, Marino F, Yamashita M, Conti E, Scholten A, Heck AJR. Back Cover: Simultaneous Assessment of Kinetic, Site-Specific, and Structural Aspects of Enzymatic Protein Phosphorylation (Angew. Chem. Int. Ed. 36/2014) Angewandte Chemie International Edition. 53: 9676-9676. DOI: 10.1002/Anie.201406162 |
0.335 |
|
| 2013 |
Buchwald G, Schüssler S, Basquin C, Le Hir H, Conti E. Crystal structure of the human eIF4AIII-CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domain Proceedings of the National Academy of Sciences of the United States of America. 110: E4611-E4618. PMID 24218557 DOI: 10.1073/Pnas.1314684110 |
0.543 |
|
| 2013 |
Makino DL, Conti E. Structure determination of an 11-subunit exosome in complex with RNA by molecular replacement Acta Crystallographica Section D: Biological Crystallography. 69: 2226-2235. PMID 24189234 DOI: 10.1107/S0907444913011438 |
0.613 |
|
| 2013 |
Hrle A, Su AA, Ebert J, Benda C, Randau L, Conti E. Structure and RNA-binding properties of the type III-A CRISPR-associated protein Csm3. Rna Biology. 10: 1670-8. PMID 24157656 DOI: 10.4161/Rna.26500 |
0.475 |
|
| 2013 |
Sharif H, Conti E. Architecture of the Lsm1-7-Pat1 complex: a conserved assembly in eukaryotic mRNA turnover. Cell Reports. 5: 283-91. PMID 24139796 DOI: 10.1016/J.Celrep.2013.10.004 |
0.701 |
|
| 2013 |
Bhaskar V, Roudko V, Basquin J, Sharma K, Urlaub H, Séraphin B, Conti E. Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex. Nature Structural & Molecular Biology. 20: 1281-8. PMID 24121231 DOI: 10.1038/Nsmb.2686 |
0.568 |
|
| 2013 |
Makino DL, Halbach F, Conti E. The RNA exosome and proteasome: Common principles of degradation control Nature Reviews Molecular Cell Biology. 14: 654-660. PMID 23989960 DOI: 10.1038/Nrm3657 |
0.837 |
|
| 2013 |
Halbach F, Reichelt P, Rode M, Conti E. The yeast ski complex: Crystal structure and rna channeling to the exosome complex Cell. 154: 814-826. PMID 23953113 DOI: 10.1016/J.Cell.2013.07.017 |
0.853 |
|
| 2013 |
Sharif H, Ozgur S, Sharma K, Basquin C, Urlaub H, Conti E. Structural analysis of the yeast Dhh1-Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions. Nucleic Acids Research. 41: 8377-90. PMID 23851565 DOI: 10.1093/Nar/Gkt600 |
0.716 |
|
| 2013 |
von Moeller H, Lerner R, Ricciardi A, Basquin C, Marzluff WF, Conti E. Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins. Nucleic Acids Research. 41: 7960-71. PMID 23804756 DOI: 10.1093/Nar/Gkt558 |
0.458 |
|
| 2013 |
Makino DL, Baumgärtner M, Conti E. Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex Nature. 494: 70-75. PMID 23376952 DOI: 10.1038/Nature11870 |
0.622 |
|
| 2013 |
Makino DL, Baumgärtner M, Conti E. Structure of the RNA-bound eukaryotic exosome complex Acta Crystallographica Section a Foundations of Crystallography. 69: s53-s53. DOI: 10.1107/S0108767313099546 |
0.583 |
|
| 2012 |
Lorentzen E, Conti E. Crystal structure of a 9-subunit archaeal exosome in pre-catalytic states of the phosphorolytic reaction. Archaea (Vancouver, B.C.). 2012: 721869. PMID 23319881 DOI: 10.1155/2012/721869 |
0.775 |
|
| 2012 |
Basquin J, Roudko VV, Rode M, Basquin C, Séraphin B, Conti E. Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction. Molecular Cell. 48: 207-18. PMID 22959269 DOI: 10.1016/J.Molcel.2012.08.014 |
0.48 |
|
| 2012 |
Melero R, Buchwald G, Castaño R, Raabe M, Gil D, Lázaro M, Urlaub H, Conti E, Llorca O. The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end. Nature Structural & Molecular Biology. 19: 498-505, S1-2. PMID 22522823 DOI: 10.1038/Nsmb.2287 |
0.516 |
|
| 2012 |
Jeyaprakash AA, Santamaria A, Jayachandran U, Chan YW, Benda C, Nigg EA, Conti E. Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface Molecular Cell. 46: 274-286. PMID 22483620 DOI: 10.1016/J.Molcel.2012.03.005 |
0.433 |
|
| 2012 |
Murachelli AG, Ebert J, Basquin C, Le Hir H, Conti E. The structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complex. Nature Structural & Molecular Biology. 19: 378-86. PMID 22388736 DOI: 10.1038/Nsmb.2242 |
0.582 |
|
| 2012 |
Halbach F, Rode M, Conti E. The crystal structure of S. cerevisiae Ski2, a DExH helicase associated with the cytoplasmic functions of the exosome. Rna (New York, N.Y.). 18: 124-34. PMID 22114319 DOI: 10.1261/Rna.029553.111 |
0.851 |
|
| 2011 |
Jeyaprakash AA, Basquin C, Jayachandran U, Conti E. Structural basis for the recognition of phosphorylated histone h3 by the survivin subunit of the chromosomal passenger complex. Structure (London, England : 1993). 19: 1625-34. PMID 22032967 DOI: 10.1016/J.Str.2011.09.002 |
0.379 |
|
| 2011 |
Chakrabarti S, Jayachandran U, Bonneau F, Fiorini F, Basquin C, Domcke S, Le Hir H, Conti E. Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2. Molecular Cell. 41: 693-703. PMID 21419344 DOI: 10.1016/J.Molcel.2011.02.010 |
0.724 |
|
| 2010 |
Malet H, Topf M, Clare DK, Ebert J, Bonneau F, Basquin J, Drazkowska K, Tomecki R, Dziembowski A, Conti E, Saibil HR, Lorentzen E. RNA channelling by the eukaryotic exosome. Embo Reports. 11: 936-42. PMID 21072061 DOI: 10.1038/Embor.2010.164 |
0.755 |
|
| 2010 |
Kashima I, Jonas S, Jayachandran U, Buchwald G, Conti E, Lupas AN, Izaurralde E. SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes & Development. 24: 2440-50. PMID 20930030 DOI: 10.1101/Gad.604610 |
0.445 |
|
| 2010 |
Nakel K, Hartung SA, Bonneau F, Eckmann CR, Conti E. Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform. Rna (New York, N.Y.). 16: 2058-67. PMID 20823118 DOI: 10.1261/Rna.2315010 |
0.498 |
|
| 2010 |
Weir JR, Bonneau F, Hentschel J, Conti E. Structural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance. Proceedings of the National Academy of Sciences of the United States of America. 107: 12139-44. PMID 20566885 DOI: 10.1073/Pnas.1004953107 |
0.638 |
|
| 2010 |
Buchwald G, Ebert J, Basquin C, Sauliere J, Jayachandran U, Bono F, Le Hir H, Conti E. Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex. Proceedings of the National Academy of Sciences of the United States of America. 107: 10050-5. PMID 20479275 DOI: 10.1073/Pnas.1000993107 |
0.497 |
|
| 2010 |
Cook AG, Conti E. Nuclear export complexes in the frame. Current Opinion in Structural Biology. 20: 247-52. PMID 20171875 DOI: 10.1016/J.Sbi.2010.01.012 |
0.775 |
|
| 2010 |
Bono F, Cook AG, Grünwald M, Ebert J, Conti E. Nuclear import mechanism of the EJC component Mago-Y14 revealed by structural studies of importin 13. Molecular Cell. 37: 211-22. PMID 20122403 DOI: 10.1016/J.Molcel.2010.01.007 |
0.767 |
|
| 2009 |
Bonneau F, Basquin J, Ebert J, Lorentzen E, Conti E. The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation. Cell. 139: 547-59. PMID 19879841 DOI: 10.1016/J.Cell.2009.08.042 |
0.783 |
|
| 2009 |
Cook AG, Fukuhara N, Jinek M, Conti E. Structures of the tRNA export factor in the nuclear and cytosolic states. Nature. 461: 60-5. PMID 19680239 DOI: 10.1038/Nature08394 |
0.838 |
|
| 2009 |
Gaitanos TN, Santamaria A, Jeyaprakash AA, Wang B, Conti E, Nigg EA. Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. The Embo Journal. 28: 1442-52. PMID 19360002 DOI: 10.1038/Emboj.2009.96 |
0.368 |
|
| 2009 |
von Moeller H, Basquin C, Conti E. The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner. Nature Structural & Molecular Biology. 16: 247-54. PMID 19219046 DOI: 10.1038/Nsmb.1561 |
0.592 |
|
| 2008 |
Lorentzen E, Conti E. Expression, reconstitution, and structure of an archaeal RNA degrading exosome. Methods in Enzymology. 447: 417-35. PMID 19161854 DOI: 10.1016/S0076-6879(08)02220-9 |
0.783 |
|
| 2008 |
Lorentzen E, Basquin J, Conti E. Structural organization of the RNA-degrading exosome. Current Opinion in Structural Biology. 18: 709-13. PMID 18955140 DOI: 10.1016/J.Sbi.2008.10.004 |
0.782 |
|
| 2008 |
Jinek M, Eulalio A, Lingel A, Helms S, Conti E, Izaurralde E. The C-terminal region of Ge-1 presents conserved structural features required for P-body localization. Rna (New York, N.Y.). 14: 1991-8. PMID 18755833 DOI: 10.1261/Rna.1222908 |
0.681 |
|
| 2008 |
Lorentzen E, Basquin J, Tomecki R, Dziembowski A, Conti E. Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family. Molecular Cell. 29: 717-28. PMID 18374646 DOI: 10.1016/J.Molcel.2008.02.018 |
0.79 |
|
| 2007 |
Jeyaprakash AA, Klein UR, Lindner D, Ebert J, Nigg EA, Conti E. Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell. 131: 271-85. PMID 17956729 DOI: 10.1016/J.Cell.2007.07.045 |
0.428 |
|
| 2007 |
Cook A, Bono F, Jinek M, Conti E. Structural biology of nucleocytoplasmic transport. Annual Review of Biochemistry. 76: 647-71. PMID 17506639 DOI: 10.1146/Annurev.Biochem.76.052705.161529 |
0.811 |
|
| 2007 |
Lorentzen E, Dziembowski A, Lindner D, Seraphin B, Conti E. RNA channelling by the archaeal exosome. Embo Reports. 8: 470-6. PMID 17380186 DOI: 10.1038/Sj.Embor.7400945 |
0.786 |
|
| 2007 |
Dziembowski A, Lorentzen E, Conti E, Séraphin B. A single subunit, Dis3, is essentially responsible for yeast exosome core activity. Nature Structural & Molecular Biology. 14: 15-22. PMID 17173052 DOI: 10.1038/Nsmb1184 |
0.712 |
|
| 2007 |
Oddone A, Lorentzen E, Basquin J, Gasch A, Rybin V, Conti E, Sattler M. Structural and biochemical characterization of the yeast exosome component Rrp40. Embo Reports. 8: 63-9. PMID 17159918 DOI: 10.1038/Sj.Embor.7400856 |
0.786 |
|
| 2007 |
Conti E. Molecular mechanisms of RNA degradation Acta Crystallographica Section A. 63: 6-6. DOI: 10.1107/S0108767307099874 |
0.488 |
|
| 2007 |
Jeyaprakash AA, Klein UR, Nigg EA, Conti E. Structure and function of Survivin-Borealin-INCENP core complex in mitosis Acta Crystallographica Section A. 63: 127-128. DOI: 10.1107/S010876730709719X |
0.392 |
|
| 2006 |
Glavan F, Behm-Ansmant I, Izaurralde E, Conti E. Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. The Embo Journal. 25: 5117-25. PMID 17053788 DOI: 10.1038/Sj.Emboj.7601377 |
0.48 |
|
| 2006 |
Jinek M, Chen YW, Clausen H, Cohen SM, Conti E. Structural insights into the Notch-modifying glycosyltransferase Fringe. Nature Structural & Molecular Biology. 13: 945-6. PMID 16964258 DOI: 10.1038/Nsmb1144 |
0.668 |
|
| 2006 |
Bono F, Ebert J, Lorentzen E, Conti E. The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA. Cell. 126: 713-25. PMID 16923391 DOI: 10.1016/J.Cell.2006.08.006 |
0.721 |
|
| 2006 |
Jinek M, Conti E. Eukaryotic expression, purification, crystallization and preliminary X-ray analysis of murine Manic Fringe. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 774-7. PMID 16880554 DOI: 10.1107/S174430910602611X |
0.627 |
|
| 2006 |
Lorentzen E, Conti E. The exosome and the proteasome: nano-compartments for degradation. Cell. 125: 651-4. PMID 16713559 DOI: 10.1016/J.Cell.2006.05.002 |
0.688 |
|
| 2006 |
Pimienta G, Gabel F, Zanier K, Conti E, Sattler M. Chemical shift backbone assignments of TAP-N, the 31 kDa cargo-binding region of the protein TAP. Journal of Biomolecular Nmr. 36: 23. PMID 16596343 DOI: 10.1007/S10858-006-0002-1 |
0.312 |
|
| 2006 |
Conti E, Müller CW, Stewart M. Karyopherin flexibility in nucleocytoplasmic transport Current Opinion in Structural Biology. 16: 237-244. PMID 16567089 DOI: 10.1016/J.Sbi.2006.03.010 |
0.368 |
|
| 2006 |
Cook A, Conti E. Dicer measures up Nature Structural and Molecular Biology. 13: 190-192. PMID 16518387 DOI: 10.1038/Nsmb0306-190 |
0.783 |
|
| 2005 |
Lorentzen E, Conti E. Structural basis of 3′ end RNA recognition and exoribonucleolytic cleavage by an exosome RNase PH core Molecular Cell. 20: 473-481. PMID 16285928 DOI: 10.1016/J.Molcel.2005.10.020 |
0.783 |
|
| 2005 |
Lorentzen E, Walter P, Fribourg S, Evguenieva-Hackenberg E, Klug G, Conti E. The archaeal exosome core is a hexameric ring structure with three catalytic subunits Nature Structural and Molecular Biology. 12: 575-581. PMID 15951817 DOI: 10.1038/Nsmb952 |
0.769 |
|
| 2005 |
Conti E, Izaurralde E. Nonsense-mediated mRNA decay: Molecular insights and mechanistic variations across species Current Opinion in Cell Biology. 17: 316-325. PMID 15901503 DOI: 10.1016/J.Ceb.2005.04.005 |
0.375 |
|
| 2005 |
Cook A, Fernandez E, Lindner D, Ebert J, Schlenstedt G, Conti E. The structure of the nuclear export receptor Cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding. Molecular Cell. 18: 355-67. PMID 15866177 DOI: 10.1016/J.Molcel.2005.03.021 |
0.749 |
|
| 2005 |
Fukuhara N, Ebert J, Unterholzner L, Lindner D, Izaurralde E, Conti E. SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. Molecular Cell. 17: 537-47. PMID 15721257 DOI: 10.1016/J.Molcel.2005.01.010 |
0.428 |
|
| 2005 |
Conti E, Bono F, Cook A, Glavan F, Lorentzen E, Jinek M, Ebert J. Transport out of the nucleus and beyond: molecular mechanisms Acta Crystallographica Section A. 61: 51-51. DOI: 10.1107/S0108767305097862 |
0.696 |
|
| 2005 |
Cook A, Fernandez E, Lindner D, Ebert J, Schlenstedt G, Conti E. Cse1: the structure of an exportin in its closed, cytosolic state Acta Crystallographica Section A. 61: 51-51. DOI: 10.1107/S0108767305097850 |
0.714 |
|
| 2004 |
Jínek M, Rehwinkel J, Lazarus BD, Izaurralde E, Hanover JA, Conti E. The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha. Nature Structural & Molecular Biology. 11: 1001-7. PMID 15361863 DOI: 10.1038/Nsmb833 |
0.701 |
|
| 2004 |
Bono F, Ebert J, Unterholzner L, Güttler T, Izaurralde E, Conti E. Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex Embo Reports. 5: 304-310. PMID 14968132 DOI: 10.1038/Sj.Embor.7400091 |
0.525 |
|
| 2004 |
Bayliss R, Sardon T, Ebert J, Lindner D, Vernos I, Conti E. Determinants for Aurora-A activation and Aurora-B discrimination by TPX2 Cell Cycle. 3: 404-407. PMID 14752279 DOI: 10.4161/Cc.3.4.777 |
0.338 |
|
| 2004 |
Fukuhara N, Fernandez E, Ebert J, Conti E, Svergun D. Conformational Variability of Nucleo-cytoplasmic Transport Factors Journal of Biological Chemistry. 279: 2176-2181. PMID 14561738 DOI: 10.1074/Jbc.M309112200 |
0.375 |
|
| 2003 |
Bayliss R, Sardon T, Vernos I, Conti E. Structural basis of Aurora-A activation by TPX2 at the mitotic spindle Molecular Cell. 12: 851-862. PMID 14580337 DOI: 10.1016/S1097-2765(03)00392-7 |
0.329 |
|
| 2003 |
Fribourg S, Conti E. Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15 Embo Reports. 4: 699-703. PMID 12835756 DOI: 10.1038/Sj.Embor.Embor883 |
0.537 |
|
| 2003 |
Fribourg S, Gatfield D, Izaurralde E, Conti E. A novel mode of RBD-protein recognition in the Y14-Mago complex Nature Structural Biology. 10: 433-439. PMID 12730685 DOI: 10.1038/Nsb926 |
0.558 |
|
| 2003 |
Conti E. The hitchhiker's guide to the nucleus Nature Structural Biology. 10: 8-9. PMID 12490886 DOI: 10.1038/Nsb0103-8 |
0.372 |
|
| 2002 |
Conti E. Structures of importins Results and Problems in Cell Differentiation. 35: 93-113. PMID 11791410 DOI: 10.1007/978-3-540-44603-3_5 |
0.38 |
|
| 2001 |
Fribourg S, Braun IC, Izaurralde E, Conti E. Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor Molecular Cell. 8: 645-656. PMID 11583626 DOI: 10.1016/S1097-2765(01)00348-3 |
0.457 |
|
| 2001 |
Conti E, Izaurralde E. Nucleocytoplasmic transport enters the atomic age Current Opinion in Cell Biology. 13: 310-319. PMID 11343901 DOI: 10.1016/S0955-0674(00)00213-1 |
0.425 |
|
| 2001 |
Braun IC, Herold A, Rode M, Conti E, Izaurralde E. Overexpression of TAP/p15 heterodimers bypasses nuclear retention and stimulates nuclear mRNA export. The Journal of Biological Chemistry. 276: 20536-43. PMID 11259411 DOI: 10.1074/Jbc.M100400200 |
0.461 |
|
| 2000 |
Liker E, Fernandez E, Izaurralde E, Conti E. The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain Embo Journal. 19: 5587-5598. PMID 11060011 DOI: 10.1093/Emboj/19.21.5587 |
0.55 |
|
| 2000 |
Conti E, Kuriyan J. Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha. Structure (London, England : 1993). 8: 329-38. PMID 10745017 DOI: 10.1016/S0969-2126(00)00107-6 |
0.515 |
|
| 1999 |
Chook YM, Cingolani G, Conti E, Stewart M, Vetter I, Wittinghofer A. Pictures in cell biology. Structures of nuclear-transport components. Trends in Cell Biology. 9: 310-1. PMID 10490335 DOI: 10.1016/S0962-8924(99)01610-4 |
0.421 |
|
| 1999 |
Mattaj IW, Conti E. Snail mail to the nucleus Nature. 399: 208-210. PMID 10353239 DOI: 10.1038/20322 |
0.449 |
|
| 1998 |
Franks NP, Jenkins A, Conti E, Lieb WR, Brick P. Structural basis for the inhibition of firefly luciferase by a general anesthetic. Biophysical Journal. 75: 2205-11. PMID 9788915 DOI: 10.1016/S0006-3495(98)77664-7 |
0.609 |
|
| 1998 |
Conti E, Uy M, Leighton L, Blobel G, Kuriyan J. Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell. 94: 193-204. PMID 9695948 DOI: 10.1016/S0092-8674(00)81419-1 |
0.577 |
|
| 1998 |
Conti E, Rivetti C, Wonacott A, Brick P. X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin. Febs Letters. 425: 229-33. PMID 9559654 DOI: 10.1016/S0014-5793(98)00235-X |
0.599 |
|
| 1997 |
Conti E, Stachelhaus T, Marahiel MA, Brick P. Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S. The Embo Journal. 16: 4174-83. PMID 9250661 DOI: 10.1093/Emboj/16.14.4174 |
0.66 |
|
| 1996 |
Conti E, Lloyd LF, Akins J, Franks NP, Brick P. Crystallization and preliminary diffraction studies of firefly luciferase from Photinus pyralis. Acta Crystallographica. Section D, Biological Crystallography. 52: 876-8. PMID 15299657 DOI: 10.1107/S0907444996002405 |
0.555 |
|
| 1996 |
Conti E, Franks NP, Brick P. Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes. Structure (London, England : 1993). 4: 287-98. PMID 8805533 DOI: 10.1016/S0969-2126(96)00033-0 |
0.642 |
|
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